Home / MALT1 / Z-VRPR-FMK trifluoroacetate salt

Z-VRPR-FMK trifluoroacetate salt

Catalog #: 4645
1 Citation Datasheet / COA / SDS

Discontinued Product

4645 has been discontinued.
View all MALT1 products.
Z-VRPR-FMK trifluoroacetate salt
1 Image
Description: Irreversible MALT1 inhibitor

Purity: ≥95%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Z-VRPR-FMK trifluoroacetate salt is an irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable.

This peptide is supplied in gross weight.

Important Information

This product is sold as a TFA salt. The stoichiometry of the salt and hydration levels vary from batch to batch. This product is sold in gross weight with the batch specific Net Product Content (free base) available on the Certificate of Analysis.

Technical Data

M. Wt
676.79 (Free Base)
Formula:
C31H49FN10O6.xCF3CO2H
Sequence:
VRPR

(Modifications: Val-1 = Z-Val, Arg-4 = DL-Arg-fluoromethylketone)

Solubility:
Soluble to 1 mg/ml in water with gentle warming
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence from UNIL under the licenced patents

Background References

  1. The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
    Rebeaud et al.
    Nat.Immunol., 2008;9:272

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Citation for Z-VRPR-FMK trifluoroacetate salt

The citations listed below are publications that use Tocris products. Selected citations for Z-VRPR-FMK trifluoroacetate salt include:

1 Citation: Showing 1 - 1

  1. Human macrophages utilize a wide range of pathogen recognition receptors to recognize Legionella pneumophila, including Toll-Like Receptor 4 engaging Legionella lipopolysaccharide and the Toll-like Receptor 3 nucleic-acid sensor
    Authors: Grigoryeva Et al.
    PLos Pathog  2021;17:e1009781

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for Z-VRPR-FMK trifluoroacetate salt

There are currently no reviews for this product. Be the first to review Z-VRPR-FMK trifluoroacetate salt and earn rewards!

Have you used Z-VRPR-FMK trifluoroacetate salt?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.