Zolantidine dimaleate

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Zolantidine (SK&F 95282) is a potent selective brain penetrating histamine H₂-receptor antagonist.
   Calcutt et al.
   Br.J.Pharmacol., 1988;93:69
3. Activity of the new histamine H₂-receptor antagonist zolantidine at cardiac and gastric H₂ receptors.
   Coruzzi et al.
   Pharmacology, 1994;48:69
4. Cardiac and gastric effects of histamine H₂ receptor antagonists: no evidence for a correlation between lipophilicity and receptor affinity.
   Coruzzi et al.
   Br.J.Pharmacol., 1996;118:1813

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