DC-SIGN/CD209: Products
DC-SIGN/CD209 (Dendritic Cell-specific ICAM-3 Grabbing Non-integrin) is a C-type lectin that is expressed as transmembrane and secreted forms. DC-SIGN binds mannose oligosaccharides on pathogens including HIV as well as self glycoproteins including ICAMs. DC-SIGN is expressed on dendritic cells and inflammatory macrophages and contributes to antigen presentation.
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