7 results for "Thrombopoietin/Tpo ELISA Kits" in Products
Thrombopoietin/Tpo ELISA Kits
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
| Reactivity: | Human |
| Sensitivity: | 18.5 pg/mL |
| Assay Range: | 31.2-2000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Sensitivity: | 20 pg/mL |
| Assay Range: | 62.5-4000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Citrate Plasma) |
| Applications: | ELISA |
For use with catalog number DTP00B
| Reactivity: | Human |
| Applications: | ELISA, Ctrl |
| Reactivity: | Mouse |
| Assay Range: | 62.5-4000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Assay Range: | 93.8-6000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Monkey |
| Sensitivity: | 46.88 pg/mL |
| Assay Range: | 78.13 - 5000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Canine |
| Sensitivity: | 6.1 pg/mL (example only; lot dependent) |
| Assay Range: | 15.6 - 1000 pg/mL (example only; lot dependent) |
| Applications: | ELISA |
