Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein
Please see our Next Generation Human Recombinant FGF basic (BT-FGFB). It combines R&D Systems quality with scalability that allows for lower price points and a solid supply chain.
Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein Summary
Product Specifications
Pro143-Ser288, with an N-terminal Ala
Analysis
Product Datasheets
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
233-FB
Formulation | Lyophilized from a 0.2 μm filtered solution in Tris-HCl and NaCl with BSA as a carrier protein. |
Reconstitution | Reconstitute at 100-250 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
233-FB/CF
Formulation | Lyophilized from a 0.2 μm filtered solution in Tris-HCl and NaCl. |
Reconstitution | Reconstitute at 100-250 μg/mL in sterile PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Stability & Storage: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Reconstitution Calculator
Background: FGF basic/FGF2/bFGF
FGF basic (also known as FGF-2 and HBGF-2) is a member of the FGF superfamily of mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic are unique from other members of the family in that they lack classical secretory signal peptides. However, they are both readily secreted from cells by an alternative secretory pathway involving direct translocation and aided by several chaperones. FGF acidic (FGF-1) and FGF basic (FGF-2) were the first two identified FGFs, and the designations acidic and basic refer to their relative isoelectric points. The full length human FGF basic protein is 288 amino acids, but there are multiple start sites which produce various shorter forms. Further adding to the complexity, a variety of forms of FGF basic are produced as a result of N-terminal extensions. These extensions affect localization of FGF basic in cellular compartments but do not affect biological activity. FGF basic has been isolated from a number of sources, including neural tissue, adrenal cortex, pituitary gland, corpus luteum, and placenta. Binding of FGF to heparin or cell surface heparan sulfate proteoglycans is required for FGF binding with high affinity to FGF receptors. FGF basic stimulates proliferation of all cells of mesodermal origin as well as many cells of neuroectodermal, ectodermal, and endodermal origin. FGF basic also induces neuronal differentiation, survival, and regeneration, and modulates embryonic development and differentiation. These observed in vitro functions suggest FGF basic may play a role in vivo in the modulation of such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, and neuronal function and neural degeneration. Additionally, FGF basic may also participate in the development of several pathological conditions resulting from excessive cell proliferation and/or angiogenesis.
- Coulier, F. et al. (1997) J. Mol. Evol. 44:43.
- Chen, C.H. et al. (2004) Curr. Vasc. Pharmacol. 2:33.
- Mohammadi, M. et al. (2005) Curr. Opin. Struct. Biol. 15:506.
- Fernig, D. et al. (1994) Prog. Growth Factor Res. 5:353.
Citations for Recombinant Human FGF basic/FGF2/bFGF (146 aa) Protein
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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A Human Brain-Chip for Modeling Brain Pathologies and Screening Blood-Brain Barrier Crossing Therapeutic Strategies
Authors: Chim, SM;Howell, K;Kokkosis, A;Zambrowicz, B;Karalis, K;Pavlopoulos, E;
Pharmaceutics
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain
Authors: Silenzi, V;D'Ambra, E;Santini, T;D'Uva, S;Setti, A;Salvi, N;Nicoletti, C;Scarfò, R;Cordella, F;Mongiardi, B;Cavezza, D;Liessi, N;Ferrucci, L;Ragozzino, D;Armirotti, A;Di Angelantonio, S;De Leonibus, E;Bozzoni, I;Morlando, M;
Cell reports
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Valproic acid-induced teratogenicity is driven by senescence and prevented by Rapamycin in human spinal cord and animal models
Authors: Pietrogrande, G;Shaker, MR;Stednitz, SJ;Soheilmoghaddam, F;Aguado, J;Morrison, SD;Zambrano, S;Tabassum, T;Javed, I;Cooper-White, J;Davis, TP;O'Brien, TJ;Scott, EK;Wolvetang, EJ;
Molecular psychiatry
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Developmental DNA demethylation is a determinant of neural stem cell identity and gliogenic competence
Authors: MacArthur, IC;Ma, L;Huang, CY;Bhavsar, H;Suzuki, M;Dawlaty, MM;
Science advances
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Discovery of NRG1-VII: the myeloid-derived class of NRG1
Authors: Berrocal-Rubio, MA;Pawer, YDJ;Dinevska, M;De Paoli-Iseppi, R;Widodo, SS;Gleeson, J;Rajab, N;De Nardo, W;Hallab, J;Li, A;Mantamadiotis, T;Clark, MB;Wells, CA;
BMC genomics
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human liver sinusoidal endothelial cells support the development of functional human pluripotent stem cell-derived Kupffer cells
Authors: Kent, GM;Atkins, MH;Lung, B;Nikitina, A;Fernandes, IM;Kwan, JJ;Andrews, TS;MacParland, SA;Keller, GM;Gage, BK;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The novel ECM protein SNED1 mediates cell adhesion via ?5?1 integrin
Authors: Pally, D;Kapoor, N;Naba, A;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Effects of FGF2 Priming and Nrf2 Activation on the Antioxidant Activity of Several Human Dental Pulp Cell Clones Derived From Distinct Donors, and Therapeutic Effects of Transplantation on Rodents With Spinal Cord Injury
Authors: Fukumitsu, H;Soumiya, H;Nakamura, K;Nagashima, K;Yamada, M;Kobayashi, H;Miwa, T;Tsunoda, A;Takeda-Kawaguchi, T;Tezuka, KI;Furukawa, S;
Cell transplantation
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis
Authors: Bisson, JA;Gordillo, M;Kumar, R;de Silva, N;Yang, E;Banks, KM;Shi, ZD;Lee, K;Yang, D;Chung, WK;Huangfu, D;Evans, T;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Primitive macrophages enable long-term vascularization of human heart-on-a-chip platforms
Authors: Landau, S;Zhao, Y;Hamidzada, H;Kent, GM;Okhovatian, S;Lu, RXZ;Liu, C;Wagner, KT;Cheung, K;Shawky, SA;Vosoughi, D;Beroncal, EL;Fernandes, I;Cummins, CL;Andreazza, AC;Keller, GM;Epelman, S;Radisic, M;
Cell stem cell
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor
Authors: Majlessipour, F;Zhu, G;Baca, N;Kumbaji, M;Hwa, V;Danielpour, M;
Heliyon
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries
Authors: Abello, J;Yin, Y;Zhao, Y;Maurer, J;Lee, J;Bodell, C;Clevenger, AJ;Burton, Z;Goeckel, ME;Lin, M;Grainger, S;Halabi, CM;Raghavan, SA;Sah, R;Stratman, AN;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Resistance to Spindle Inhibitors in Glioblastoma Depends on STAT3 and Therapy Induced Senescence
Authors: Zarco, N;Dovas, A;de Araujo Farias, V;Nagaiah, NK;Haddock, A;Sims, PA;Hambardzumyan, D;Meyer, CT;Canoll, P;Rosenfeld, SS;Kenchappa, RS;
bioRxiv : the preprint server for biology
Species: Human, Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2
Authors: Shaker, MR;Slonchak, A;Al-Mhanawi, B;Morrison, SD;Sng, JDJ;Cooper-White, J;Khromykh, AA;Wolvetang, EJ;
Science advances
Species: Human
Sample Types: Spheroid
Applications: Cell Culture -
Antisense oligonucleotide therapeutic approach for Timothy syndrome
Authors: Chen, X;Birey, F;Li, MY;Revah, O;Levy, R;Thete, MV;Reis, N;Kaganovsky, K;Onesto, M;Sakai, N;Hudacova, Z;Hao, J;Meng, X;Nishino, S;Huguenard, J;Pa?ca, SP;
Nature
Species: Human
Sample Types: Organoid
Applications: Bioassay -
Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays
Authors: Shrestha, S;Acharya, P;Kang, SY;Vanga, MG;Lekkala, VKR;Liu, J;Yang, Y;Joshi, P;Lee, MY;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: cell culture
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Human assembloid model of the ascending neural sensory pathway
Authors: Kim, JI;Imaizumi, K;Thete, MV;Hudacova, Z;Jurju?, O;Amin, ND;Scherrer, G;Pa?ca, SP;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Organoid
Applications: Bioassay -
YTHDF2 governs muscle size through a targeted modulation of proteostasis
Authors: Gilbert, CJ;Rabolli, CP;Golubeva, VA;Sattler, KM;Wang, M;Ketabforoush, A;Arnold, WD;Lepper, C;Accornero, F;
Nature communications
Species: Mouse, Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Regulation of Corneal Stromal Cell Behavior by Modulating Curvature Using a Hydraulically Controlled Organ Chip Array
Authors: Kim, M;Choi, K;Krizaj, D;Kim, J;
Research square
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Perlecan (HSPG2) promotes structural, contractile, and metabolic development of human cardiomyocytes
Authors: Johnson, BB;Cosson, MV;Tsansizi, LI;Holmes, TL;Gilmore, T;Hampton, K;Song, OR;Vo, NTN;Nasir, A;Chabronova, A;Denning, C;Peffers, MJ;Merry, CLR;Whitelock, J;Troeberg, L;Rushworth, SA;Bernardo, AS;Smith, JGW;
Cell reports
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fibroblast growth factor 8b (FGF-8b) enhances myogenesis and inhibits adipogenesis in rotator cuff muscle cell populations in vitro
Authors: Otsuka, T;Kan, HM;Mengsteab, PY;Tyson, B;Laurencin, CT;
Proceedings of the National Academy of Sciences of the United States of America
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma
Authors: Liu, S;Qin, Z;Mao, Y;Wang, N;Zhang, W;Wang, Y;Chen, Y;Jia, L;Peng, X;
Theranostics
Species: Mouse
Sample Types:
Applications: Cell Culture -
Dystrophin deficiency impairs cell junction formation during embryonic myogenesis
Authors: Mozin, E;Massouridès, E;Mournetas, V;Lièvre, C;Bourdon, A;Jackson, DL;Packer, JS;Trapnell, C;Guiner, CL;Adjali, O;Pinset, C;Mack, DL;Dupont, JB;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Novel Methionine Aminopeptidase 2 Inhibitor M8891 Synergizes with VEGF Receptor Inhibitors to Inhibit Tumor Growth of Renal Cell Carcinoma Models
Authors: Friese-Hamim, M;Ortiz-Ruiz, MJ;Bogatyrova, O;Keil, M;Rohdich, F;Blume, B;Leuthner, B;Czauderna, F;Hahn, D;Jabs, J;Jaehrling, F;Heinrich, T;Kellner, R;Chan, K;Tong, AHY;Wienke, D;Moffat, J;Blaukat, A;Zenke, FT;
Molecular cancer therapeutics
Species: Transgenic Mouse
Sample Types: In Vivo
Applications: In vivo assay -
Precise Therapeutic Targeting of Distinct NRXN1+/- Mutations
Authors: Fernando, MB;Fan, Y;Zhang, Y;Kammourh, S;Murphy, AN;Ghorbani, S;Onatzevitch, R;Pero, A;Padilla, C;Cao, L;Williams, S;Fang, G;Slesinger, PA;Brennand, KJ;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Embryoid Bodies
Applications: Bioassay -
Single-cell long-read sequencing in human cerebral organoids uncovers cell-type-specific and autism-associated exons
Authors: Yang, Y;Yang, R;Kang, B;Qian, S;He, X;Zhang, X;
Cell reports
Species: Human
Sample Types: Organoid
Applications: Bioassay -
Cell-based screen identifies porphyrins as FGFR3 activity inhibitors with therapeutic potential for achondroplasia and cancer
Authors: Lin, YW;Kao, HJ;Chen, WT;Kao, CF;Wu, JY;Chen, YT;Lee, YC;
JCI insight
Species: Mouse, Transgenic Mouse, Human
Sample Types: Transfected Whole Cells, Whole Cells, Whole Tissue
Applications: Bioassay -
Kirigami electronics for long-term electrophysiological recording of human neural organoids and assembloids
Authors: Yang, X;Forró, C;Li, TL;Miura, Y;Zaluska, TJ;Tsai, CT;Kanton, S;McQueen, JP;Chen, X;Mollo, V;Santoro, F;Pa?ca, SP;Cui, B;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Organoids
Applications: Bioassay -
Altered Mitochondrial Function and Accelerated Aging Phenotype in Neural Stem Cells Derived from Dnm1l Knockout Embryonic Stem Cells
Authors: Na, SB;Seo, BJ;Hong, TK;Oh, SY;Hong, YJ;Song, JH;Uhm, SJ;Hong, K;Do, JT;
International journal of molecular sciences
Species: Mouse
Sample Types: Embryoid Bodies, Transfected Whole Cells
Applications: Bioassay -
Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
Authors: Gutierrez-Ruiz, OL;Johnson, KM;Krueger, EW;Nooren, RE;Cruz-Reyes, N;Heppelmann, CJ;Hogenson, TL;Fernandez-Zapico, ME;McNiven, MA;Razidlo, GL;
Cell reports
Species: Human
Sample Types: Whole Cells
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Efficient high-precision homology-directed repair-dependent genome editing by HDRobust
Authors: Riesenberg, S;Kanis, P;Macak, D;Wollny, D;Düsterhöft, D;Kowalewski, J;Helmbrecht, N;Maricic, T;Pääbo, S;
Nature methods
Species: Human
Sample Types: Organoids
Applications: Bioassay -
Identification of ligand-receptor pairs that drive human astrocyte development
Authors: Voss, AJ;Lanjewar, SN;Sampson, MM;King, A;Hill, EJ;Sing, A;Sojka, C;Bhatia, TN;Spangle, JM;Sloan, SA;
Nature neuroscience
Species: Human
Sample Types: Organoid
Applications: Bioassay -
Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
Authors: Alber, AB;Marquez, HA;Ma, L;Kwong, G;Thapa, BR;Villacorta-Martin, C;Lindstrom-Vautrin, J;Bawa, P;Wang, F;Luo, Y;Ikonomou, L;Shi, W;Kotton, DN;
Nature communications
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay -
SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity
Authors: Martínez-Mármol, R;Giordano-Santini, R;Kaulich, E;Cho, AN;Przybyla, M;Riyadh, MA;Robinson, E;Chew, KY;Amor, R;Meunier, FA;Balistreri, G;Short, KR;Ke, YD;Ittner, LM;Hilliard, MA;
Science advances
Species: Human
Sample Types: Organoid
Applications: Bioassay -
Lipid droplet-associated lncRNA LIPTER preserves cardiac lipid metabolism
Authors: Han, L;Huang, D;Wu, S;Liu, S;Wang, C;Sheng, Y;Lu, X;Broxmeyer, HE;Wan, J;Yang, L;
Nature cell biology
Species: Human
Sample Types: Whole Cells, Embryoid Bodies
Applications: Bioassay -
A distal lung organoid model to study interstitial lung disease, viral infection and human lung development
Authors: Matkovic Leko, I;Schneider, RT;Thimraj, TA;Schrode, N;Beitler, D;Liu, HY;Beaumont, K;Chen, YW;Snoeck, HW;
Nature protocols
Species: Human
Sample Types: Organoid
Applications: Bioassay -
Deriving Schwann cells from hPSCs enables disease modeling and drug discovery for diabetic peripheral neuropathy
Authors: Majd, H;Amin, S;Ghazizadeh, Z;Cesiulis, A;Arroyo, E;Lankford, K;Majd, A;Farahvashi, S;Chemel, AK;Okoye, M;Scantlen, MD;Tchieu, J;Calder, EL;Le Rouzic, V;Shibata, B;Arab, A;Goodarzi, H;Pasternak, G;Kocsis, JD;Chen, S;Studer, L;Fattahi, F;
Cell stem cell
Species: Human
Sample Types: Whole Cells, Spheroid
Applications: Bioassay -
Engineering Adenoviral Vectors with Improved GBM Selectivity
Authors: Bates, EA;Lovatt, C;Plein, AR;Davies, JA;Siebzehnrubl, FA;Parker, AL;
Viruses
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays
Authors: Hartmann, J;Henschel, N;Bartmann, K;D�nmez, A;Brockerhoff, G;Koch, K;Fritsche, E;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Lovastatin promotes the self-renewal of murine and primate spermatogonial stem cells
Authors: C Li, Z Yao, L Ma, X Song, W Wang, C Wan, S Ren, D Chen, Y Zheng, YT Zhu, G Chang, S Wu, K Miao, F Luo, XY Zhao
Stem Cell Reports, 2023-04-11;18(4):969-984.
Species: Human
Sample Types: Whole Cell
Applications: Bioassay -
Generation of three induced Pluripotent Stem Cell lines from individuals with Hypomyelination with Atrophy of Basal Ganglia and Cerebellum caused by a c.745G>A (p.D249N) autosomal dominant mutation in TUBB4A
Authors: AA Almad, L Garcia, A Takanohash, A Gagne, W Yang, J Ann McGuir, D French, A Vanderver
Stem Cell Research, 2023-03-26;69(0):103083.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Sorting-nexin-10 sustains platelet-derived growth factor receptor signaling in glioblastoma stem cells via endosomal protein sorting
Authors: RC Gimple, G Zhang, S Wang, T Huang, J Lee, S Taori, D Lv, D Dixit, ME Halbert, AR Morton, RL Kidwell, Z Dong, BC Prager, L Kim, Z Qiu, L Zhao, Q Xie, Q Wu, S Agnihotri, JN Rich
JCI Insight, 2023-03-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease
Authors: Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer
Cell Stem Cell, 2023-03-02;30(3):264-282.e9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes
Authors: AR Dicks, GI Maksaev, Z Harissa, A Savadipour, R Tang, N Steward, W Liedtke, CG Nichols, CL Wu, F Guilak
Elife, 2023-02-22;12(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development
Authors: JM Gonzalez-M, S Ivins, CL Andoniadou, P Le Tissier, P Scambler, JP Martinez-B
PLoS ONE, 2023-02-17;18(2):e0280001.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay -
Circadian regulator CLOCK promotes tumor angiogenesis in glioblastoma
Authors: L Pang, M Dunterman, W Xuan, A Gonzalez, Y Lin, WH Hsu, F Khan, RS Hagan, WA Muller, AB Heimberger, P Chen
Cell Reports, 2023-02-14;42(2):112127.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pervasive environmental chemicals impair oligodendrocyte development
Authors: EF Cohn, BLL Clayton, M Madhavan, S Yacoub, Y Federov, K Paul-Fried, TJ Shafer, PJ Tesar
bioRxiv : the preprint server for biology, 2023-02-12;0(0):.
Species: Human, Mouse
Sample Types: Organoid, Whole Cells
Applications: Bioassay -
Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome
Authors: NB Campbell, Y Patel, TL Moore, M Medalla, E Zeldich
International Journal of Molecular Sciences, 2023-02-09;24(4):.
Species: Human
Sample Types: Spheroid
Applications: Bioassay -
Transplanted human iPSC-derived vascular endothelial cells promote functional recovery by recruitment of regulatory T cells to ischemic white matter in the brain
Authors: B Xu, H Shimauchi-, Y Yoshimoto, T Sadakata, Y Ishizaki
Journal of Neuroinflammation, 2023-01-17;20(1):11.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8
Authors: N Wang, J He, X Feng, S Liao, Y Zhao, F Tang, K Kee
Elife, 2023-01-05;12(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Reconstruction of distinct vertebrate gastrulation modes via modulation of key cell behaviors in the chick embryo
Authors: M Chuai, G Serrano Ná, M Serra, L Mahadevan, CJ Weijer
Science Advances, 2023-01-04;9(1):eabn5429.
Species: Chick
Sample Types: Embryos
Applications: Bioassay -
hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease
Authors: Y Fan, J Hackland, A Baggiolini, LY Hung, H Zhao, P Zumbo, P Oberst, AP Minotti, E Hergenrede, S Najjar, Z Huang, NM Cruz, A Zhong, M Sidharta, T Zhou, E de Stanchi, D Betel, RM White, M Gershon, KG Margolis, L Studer
Cell Stem Cell, 2023;30(3):264-282.e9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses
Authors: L Feige, T Kozaki, G Dias de Me, V Guillemot, F Larrous, F Ginhoux, H Bourhy
Viruses, 2022-12-29;15(1):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Periostin promotes ovarian cancer metastasis by enhancing M2 macrophages and cancer-associated fibroblasts via integrin-mediated NF-kappaB and TGF-beta2 signaling
Authors: SC Lin, YC Liao, PM Chen, YY Yang, YH Wang, SL Tung, CM Chuang, YW Sung, TH Jang, SE Chuang, LH Wang
Journal of Biomedical Science, 2022-12-22;29(1):109.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Glioblastoma cells have increased capacity to repair radiation-induced DNA damage after migration to the olfactory bulb
Authors: C Degorre, IC Sutton, SL Lehman, UT Shankavara, K Camphausen, PJ Tofilon
Cancer Cell International, 2022-12-08;22(1):389.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity
Authors: JE Kaserman, RB Werder, F Wang, T Matte, MI Higgins, M Dodge, J Lindstrom-, P Bawa, A Hinds, E Bullitt, IS Caballero, X Shi, RE Gerszten, N Brunetti-P, M Liesa, C Villacorta, AN Hollenberg, DN Kotton, AA Wilson
Cell Reports, 2022-12-06;41(10):111775.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
Authors: AA Widjaja, S Viswanatha, SG Shekeran, E Adami, WW Lim, S Chothani, J Tan, JWT Goh, HM Chen, SY Lim, CM Boustany-K, J Hawkins, E Petretto, N Hübner, S Schafer, TM Coffman, SA Cook
Nature Communications, 2022-12-05;13(1):7497.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models
Authors: HF Wu, W Yu, K Saito-Diaz, CW Huang, J Carey, F Lefcort, GW Hart, HX Liu, N Zeltner
Nature Communications, 2022-11-17;13(1):7032.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Proteo-genomic characterization of virus-associated liver cancers reveals potential subtypes and therapeutic targets
Authors: M Fujita, MM Chen, DR Siwak, S Sasagawa, A Oosawa-Tat, K Arihiro, A Ono, R Miura, K Maejima, H Aikata, M Ueno, S Hayami, H Yamaue, K Chayama, JS Lee, Y Lu, GB Mills, H Liang, SS Nishizuka, H Nakagawa
Nature Communications, 2022-10-29;13(1):6481.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Developmental Potency and Metabolic Traits of Extended Pluripotency Are Faithfully Transferred to Somatic Cells via Cell Fusion-Induced Reprogramming
Authors: JH Song, J Choi, YJ Hong, H La, TK Hong, K Hong, JT Do
Cells, 2022-10-17;11(20):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Efficient Gene Expression in Human Stem Cell Derived-Cortical Organoids Using Adeno Associated Virus
Authors: AN Cho, F Bright, N Morey, C Au, LM Ittner, YD Ke
Cells, 2022-10-11;11(20):.
Species: Human
Sample Types: Organoid
Applications: Bioassay -
Cross-lineage potential of Ascl1 uncovered by comparing diverse reprogramming regulatomes
Authors: H Wang, B Keepers, Y Qian, Y Xie, M Colon, J Liu, L Qian
Cell Stem Cell, 2022-10-06;29(10):1491-1504.e9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Endostatin in 3D Fibrin Hydrogel Scaffolds Promotes Chondrogenic Differentiation in Swine Neonatal Meniscal Cells
Authors: VR Herrera Mi, B Canciani, L Mangiavini, JFS Filipe, L Aidos, M Pallaoro, GM Peretti, P Pocar, SC Modina, A Di Giancam
Biomedicines, 2022-09-27;10(10):.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay -
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
Authors: P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, B Zeng, JM Vicari, W Zhang, K Girdhar, KG Townsley, R Misir, CommonMind, KJ Brennand, V Haroutunia, G Voloudakis, JF Fullard, P Roussos
Nature Genetics, 2022-09-26;54(10):1493-1503.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Modeling human multi-lineage heart field development with pluripotent stem cells
Authors: D Yang, J Gomez-Garc, S Funakoshi, T Tran, I Fernandes, GD Bader, MA Laflamme, GM Keller
Cell Stem Cell, 2022-09-01;29(9):1382-1401.e8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment
Authors: Y Tang, DJ Kwiatkowsk, EP Henske
Nature Communications, 2022-08-26;13(1):5018.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay
Authors: S Martin, KC Allan, O Pinkard, T Sweet, PJ Tesar, J Coller
Nature Communications, 2022-08-25;13(1):5003.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems
Authors: K Kishimoto, K Iwasawa, A Sorel, C Ferran-Her, L Han, M Morimoto, JM Wells, T Takebe, AM Zorn
Nature Protocols, 2022-08-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair
Authors: D Hao, L Lu, H Song, Y Duan, J Chen, R Carney, JJ Li, P Zhou, J Nolta, KS Lam, JK Leach, DL Farmer, A Panitch, A Wang
Theranostics, 2022-08-08;12(13):6021-6037.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
ZnT8 loss-of-function accelerates functional maturation of hESC-derived beta cells and resists metabolic stress in diabetes
Authors: Q Ma, Y Xiao, W Xu, M Wang, S Li, Z Yang, M Xu, T Zhang, ZN Zhang, R Hu, Q Su, F Yuan, T Xiao, X Wang, Q He, J Zhao, ZJ Chen, Z Sheng, M Chai, H Wang, W Shi, Q Deng, X Cheng, W Li
Nature Communications, 2022-07-16;13(1):4142.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1
Authors: MK Eltahir, M Nakamori, S Hattori, T Kimura, H Mochizuki, S Nagano
PLoS ONE, 2022-07-01;17(7):e0269683.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
NR2F1 is a barrier to dissemination of early stage breast cancer cells
Authors: C Rodriguez-, N Kale, MJ Carlini, N Shrivastav, AA Rodrigues, B Khalil, JJ Bravo-Cord, M Alexander, J Ji, Y Hong, F Behbod, MS Sosa
Cancer Research, 2022-06-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting
Authors: Y Tsujisaka, T Hatani, C Okubo, R Ito, A Kimura, M Narita, K Chonabayas, S Funakoshi, A Lucena-Cac, T Toyoda, K Osafune, T Kimura, H Saito, Y Yoshida
Stem Cell Reports, 2022-06-09;0(0):.
Species: Human
Sample Types: Embryoid Bodies
Applications: Bioassay -
Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
Authors: MK Samanta, S Gayen, C Harris, E Maclary, Y Murata-Nak, RM Malcore, RS Porter, PM Garay, CN Vallianato, PB Samollow, S Iwase, S Kalantry
Nature Communications, 2022-05-11;13(1):2602.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cnot8 eliminates na�ve regulation networks and is essential for na�ve-to-formative pluripotency transition
Authors: Y Quan, M Wang, C Xu, X Wang, Y Wu, D Qin, Y Lin, X Lu, F Lu, L Li
Nucleic Acids Research, 2022-05-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Preventing erosion of X-chromosome inactivation in human embryonic stem cells
Authors: M Cloutier, S Kumar, E Buttigieg, L Keller, B Lee, A Williams, S Mojica-Per, I Erliandri, AMD Rocha, K Cadigan, GD Smith, S Kalantry
Nature Communications, 2022-05-06;13(1):2516.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Integrative molecular roadmap for direct conversion of fibroblasts into myocytes and myogenic progenitor cells
Authors: I Kim, A Ghosh, N Bundschuh, L Hinte, E Petrosyan, F von Meyenn, O Bar-Nur
Science Advances, 2022-04-06;8(14):eabj4928.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors
Authors: BK Gage, S Merlin, C Olgasi, A Follenzi, GM Keller
Cell Reports, 2022-04-05;39(1):110621.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Localized astrogenesis regulates gyrification of the cerebral cortex
Authors: Y Shinmyo, K Saito, T Hamabe-Hor, N Kameya, A Ando, K Kawasaki, TAD Duong, M Sakashita, J Roboon, T Hattori, T Kannon, K Hosomichi, M Slezak, MG Holt, A Tajima, O Hori, H Kawasaki
Science Advances, 2022-03-11;8(10):eabi5209.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3
Authors: Z Pan, R Zhao, B Li, Y Qi, W Qiu, Q Guo, S Zhang, S Zhao, H Xu, M Li, Z Gao, Y Fan, J Xu, H Wang, S Wang, J Qiu, Q Wang, X Guo, L Deng, P Zhang, H Xue, G Li
Molecular Cancer, 2022-01-14;21(1):16.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
VRK2 activates TNFalpha/NF-kappaB signaling by phosphorylating IKKbeta in pancreatic cancer
Authors: J Chen, K Qiao, C Zhang, X Zhou, Q Du, Y Deng, L Cao
International journal of biological sciences, 2022-01-09;18(3):1288-1302.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Engineering brain assembloids to interrogate human neural circuits
Authors: Y Miura, MY Li, O Revah, SJ Yoon, G Narazaki, SP Pa?ca
Nature Protocols, 2022-01-06;17(1):15-35.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Intracameral Microimaging of Maturation of Human iPSC Derivatives into Islet Endocrine Cells
Authors: K Zhao, Y Shi, J Yu, L Yu, A Mael, Y Li, A Kolton, T Joyce, J Odorico, PO Berggren, SN Yang
Cell Transplantation, 2022-01-01;31(0):9636897211066.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL
Authors: G Iannello, A Patel, D Sirabella, B Corneo, VV Thaker
Stem Cell Research, 2021-12-23;59(0):102635.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Programmed genomic instability regulates neural transdifferentiation of human brain microvascular pericytes
Authors: S Rezaei-Lot, F Vujovic, M Simonian, N Hunter, RM Farahani
Genome Biology, 2021-12-09;22(1):334.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells
Authors: AK Eicher, DO Kechele, N Sundaram, HM Berns, HM Poling, LE Haines, JG Sanchez, K Kishimoto, M Krishnamur, L Han, AM Zorn, MA Helmrath, JM Wells
Cell Stem Cell, 2021-12-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Protein kinase C? and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
Authors: RS Kenchappa, Y Liu, MG Argenziano, MA Banu, AC Mladek, R West, A Luu, A Quiñones-H, D Hambardzum, V Justilien, M Leitges, JN Sarkaria, PA Sims, P Canoll, NR Murray, AP Fields, SS Rosenfeld
Cell Reports, 2021-11-23;37(8):110054.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells
Authors: CW Lee, YF Chen, AW Hsiao, AY Wang, OY Shen, BY Wang, LWC Ho, WT Lin, CHJ Choi, OK Lee
Journal of advanced research, 2021-11-19;39(0):73-88.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
ABHD5 inhibits YAP-induced c-Met overexpression and colon cancer cell stemness via suppressing YAP methylation
Authors: Y Gu, Y Chen, L Wei, S Wu, K Shen, C Liu, Y Dong, Y Zhao, Y Zhang, C Zhang, W Zheng, J He, Y Wang, Y Li, X Zhao, H Wang, J Tan, L Wang, Q Zhou, G Xie, H Liang, J Ou
Nature Communications, 2021-11-18;12(1):6711.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of Primordial Germ Cell-like Cells from iPSCs Derived from Turner Syndrome Patients
Authors: AF de Souza, FF Bressan, NCG Pieri, RC Botigelli, T Revay, SK Haddad, DT Covas, ES Ramos, WA King, FV Meirelles
Cells, 2021-11-10;10(11):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neonatal Porcine Germ Cells Dedifferentiate and Display Osteogenic and Pluripotency Properties
Authors: MA Fayaz, GDS Rosa, A Honaramooz
Cells, 2021-10-20;10(11):.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay -
The fate of notch-1 transcript is linked to cell cycle dynamics by activity of a natural antisense transcript
Authors: F Vujovic, S Rezaei-Lot, N Hunter, RM Farahani
Nucleic Acids Research, 2021-10-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD200 -dependent and -independent immune-modulatory functions of neural stem cells
Authors: T Arad, N Fainstein, S Goldfarb, M Lachish, T Ganz, T Ben-Hur
Stem Cell Research, 2021-10-07;56(0):102559.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
BRD4 orchestrates genome folding to promote neural crest differentiation
Authors: R Linares-Sa, W Kim, NA Bolar, H Zhang, BA Koch-Bojal, S Yoon, PP Shah, A Karnay, DS Park, JM Luppino, SC Nguyen, A Padmanabha, CL Smith, A Poleshko, Q Wang, L Li, D Srivastava, G Vahedi, GH Eom, GA Blobel, EF Joyce, R Jain
Nature Genetics, 2021-10-05;53(10):1480-1492.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease.
Authors: de Rus Jacquet A, Tancredi J, Lemire A, DeSantis M, Li W, O'Shea E
Elife, 2021-09-30;10(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence
Authors: Q Heydt, C Xintaropou, A Clear, M Austin, I Pislariu, F Miraki-Mou, P Cutillas, K Korfi, M Calaminici, W Cawthorn, K Suchacki, A Nagano, JG Gribben, M Smith, JD Cavenagh, H Oakervee, A Castleton, D Taussig, B Peck, A Wilczynska, L McNaughton, D Bonnet, F Mardakheh, B Patel
Nature Communications, 2021-09-17;12(1):5507.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models
Authors: Y Aghazadeh, F Poon, F Sarangi, FTM Wong, ST Khan, X Sun, R Hatkar, BJ Cox, SS Nunes, MC Nostro
Cell Stem Cell, 2021-09-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells
Authors: T Jia, T Jacquet, F Dalonneau, P Coudert, E Vaganay, C Exbrayat-H, J Vollaire, V Josserand, F Ruggiero, JL Coll, B Eymin
Bmc Biology, 2021-08-25;19(1):173.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
3D Bioprinting Mesenchymal Stem Cell-Derived Neural Tissues Using a Fibrin-Based Bioink
Authors: M Restan Per, R Sharma, NZ Masri, SM Willerth
Biomolecules, 2021-08-21;11(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
Authors: AV Parent, G Faleo, J Chavez, M Saxton, DI Berrios, NR Kerper, Q Tang, M Hebrok
Cell Reports, 2021-08-17;36(7):109538.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Detection and quantification of human-specific mRNA from hepatocyte-like cells derived from dental pulp using real-time polymerase chain reaction
Authors: N Shimamura, K Fujii, S Ohkoshi
Journal of oral biosciences, 2021-07-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
Authors: SM Dieter, C Siegl, PL Codó, M Huerta, AL Ostermann-, E Schulz, MK Zowada, S Martin, K Laaber, A Nowrouzi, M Blatter, S Kreth, F Westermann, A Benner, U Uhrig, K Putzker, J Lewis, A Haegebarth, D Mumberg, SJ Holton, J Weiske, LM Toepper, U Scheib, G Siemeister, CR Ball, B Kuster, G Stoehr, H Hahne, S Johannes, M Lange, F Herbst, H Glimm
Cell Reports, 2021-07-20;36(3):109394.
Species: Human
Sample Types: Organoid
Applications: Bioassay -
Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma
Authors: J Dong, J Li, Y Li, Z Ma, Y Yu, CY Wang
Nature Communications, 2021-06-25;12(1):3974.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Porcine Decellularized Diaphragm Hydrogel: A New Option for Skeletal Muscle Malformations
Authors: D Boso, E Carraro, E Maghin, S Todros, A Dedja, M Giomo, N Elvassore, P De Coppi, PG Pavan, M Piccoli
Biomedicines, 2021-06-22;9(7):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Uncovering the RNA-binding protein landscape in the pluripotency network of human embryonic stem cells
Authors: S Dvir, A Argoetti, C Lesnik, M Roytblat, K Shriki, M Amit, T Hashimshon, Y Mandel-Gut
Cell Reports, 2021-06-01;35(9):109198.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Axonal generation of amyloid-&beta from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes
Authors: R Bhattachar, SE Black, MS Lotlikar, RH Fenn, M Jorfi, DM Kovacs, RE Tanzi
Cell Reports, 2021-05-18;35(7):109134.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance
Authors: C Wang, Y Li, L Jia, JK Kim, J Li, P Deng, W Zhang, PH Krebsbach, CY Wang
Cell Stem Cell, 2021-05-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling
Authors: A Abdullah, C Herdenberg, H Hedman
Scientific Reports, 2021-04-21;11(1):8585.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Primate cell fusion disentangles gene regulatory divergence in neurodevelopment
Authors: RM Agoglia, D Sun, F Birey, SJ Yoon, Y Miura, K Sabatini, SP Pa?ca, HB Fraser
Nature, 2021-03-17;0(0):.
Species: Human, Primate
Sample Types: Organoid, Whole Cells
Applications: Bioassay -
Engineered glycomaterial implants orchestrate large-scale functional repair of brain tissue chronically after severe traumatic brain injury
Authors: CV Latchouman, MI Betancur, GA Simchick, MK Sun, R Forghani, CE Lenear, A Ahmed, R Mohankumar, N Balaji, HD Mason, SA Archer-Har, P Azadi, PV Holmes, Q Zhao, RV Bellamkond, L Karumbaiah
Science Advances, 2021-03-05;7(10):.
Species: Rat
Sample Types: In Vivo
Applications: Bioassay -
Neuronal Differentiation from Induced Pluripotent Stem Cell-Derived Neurospheres by the Application of Oxidized Alginate-Gelatin-Laminin Hydrogels
Authors: T Distler, I Lauria, R Detsch, CM Sauter, F Bendt, J Kapr, S Rütten, AR Boccaccini, E Fritsche
Biomedicines, 2021-03-05;9(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment
Authors: X Dong, L Yang, K Liu, X Ji, C Tang, W Li, L Ma, Y Mei, T Peng, B Feng, Z Wu, Q Tang, Y Gao, K Yan, W Zhou, M Xiong
Cell Reports, 2021-03-02;34(9):108802.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The in vitro multilineage differentiation and maturation of lung and airway cells from human pluripotent stem cell-derived lung progenitors in 3D
Authors: AL Rodrigues, HY Liu, YW Chen, M Porotto, A Moscona, HW Snoeck
Nature Protocols, 2021-03-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Long-term maturation of human cortical organoids matches key early postnatal transitions
Authors: A Gordon, SJ Yoon, SS Tran, CD Makinson, JY Park, J Andersen, AM Valencia, S Horvath, X Xiao, JR Huguenard, SP Pa?ca, DH Geschwind
Nature Neuroscience, 2021-02-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Formative pluripotent stem cells show features of epiblast cells poised for gastrulation
Authors: X Wang, Y Xiang, Y Yu, R Wang, Y Zhang, Q Xu, H Sun, ZA Zhao, X Jiang, X Wang, X Lu, D Qin, Y Quan, J Zhang, N Shyh-Chang, H Wang, N Jing, W Xie, L Li
Cell Research, 2021-02-19;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Chronic intermittent hypoxia promoted lung cancer stem cell-like properties via enhancing Bach1 expression
Authors: S Hao, X Zhu, Z Liu, X Wu, S Li, P Jiang, L Jiang
Respiratory Research, 2021-02-17;22(1):58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A digital single-molecule nanopillar SERS platform for predicting and monitoring immune toxicities in immunotherapy
Authors: J Li, A Wuethrich, AAI Sina, HH Cheng, Y Wang, A Behren, PN Mainwaring, M Trau
Nature Communications, 2021-02-17;12(1):1087.
Species: Human
Sample Types: Reference Standard
-
Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets
Authors: T Wang, AR Pine, AG Kotini, H Yuan, L Zamparo, DT Starczynow, C Leslie, EP Papapetrou
Cell Stem Cell, 2021-02-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
Authors: PP Shah, W Lv, JH Rhoades, A Poleshko, D Abbey, MA Caporizzo, R Linares-Sa, JG Heffler, N Sayed, D Thomas, Q Wang, LJ Stanton, K Bedi, MP Morley, TP Cappola, AT Owens, KB Margulies, DB Frank, JC Wu, DJ Rader, W Yang, BL Prosser, K Musunuru, R Jain
Cell Stem Cell, 2021-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis
Authors: CL Wu, A Dicks, N Steward, R Tang, DB Katz, YR Choi, F Guilak
Nature Communications, 2021-01-13;12(1):362.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Control of mesenchymal cell fate via application of FGF-8b in vitro
Authors: T Otsuka, PY Mengsteab, CT Laurencin
Stem Cell Research, 2021-01-07;51(0):102155.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
Authors: JP Russell, X Lim, A Santambrog, V Yianni, Y Kemkem, B Wang, M Fish, S Haston, A Grabek, S Hallang, EJ Lodge, AL Patist, A Schedl, P Mollard, R Nusse, CL Andoniadou
Elife, 2021-01-05;10(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The histone demethylase KDM2B regulates human primordial germ cell-like cells specification
Authors: W Yuan, Z Yao, V Veerapandi, X Yang, X Wang, D Chen, L Ma, C Li, Y Zheng, F Luo, XY Zhao
International journal of biological sciences, 2021-01-01;17(2):527-538.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
Authors: C Zhong, P Li, S Argade, L Liu, A Chilla', W Liang, H Xin, B Eliceiri, B Choudhury, N Ferrara
Nature Communications, 2020-12-10;11(1):6330.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
MicroRNA-155 contributes to plexiform neurofibroma growth downstream of MEK
Authors: Y Na, A Hall, K Choi, L Hu, J Rose, RA Coover, A Miller, RF Hennigan, E Dombi, MO Kim, S Subramania, N Ratner, J Wu
Oncogene, 2020-12-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology
Authors: N Zhang, J Mendieta-E, A Magli, KC Lilja, RCR Perlingeir, MA Marti-Reno, A Tsirigos, BD Dynlacht
Nature Communications, 2020-12-04;11(1):6222.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification
Authors: J Qiu, S Nordling, HH Vasavada, EC Butcher, KK Hirschi
Cell Rep, 2020-12-01;33(9):108465.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Female human primordial germ cells display X-chromosome dosage compensation despite the absence of X-inactivation
Authors: T Chitiashvi, I Dror, R Kim, FM Hsu, R Chaudhari, E Pandolfi, D Chen, S Liebscher, K Schenke-La, K Plath, A Clark
Nature Cell Biology, 2020-11-30;22(12):1436-1446.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
TGF-&beta-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness
Authors: T Matsumura, T Fujimoto, A Futakuchi, Y Takihara, F Watanabe-K, E Takahashi, M Inoue-Moch, H Tanihara, T Inoue
PLoS ONE, 2020-11-18;15(11):e0242626.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells
Authors: F Rajabi, WY Liu-Bordes, M Pinskaya, F Dominika, G Kratassiou, G Pinna, S Nanni, A Farsetti, C Gespach, A Londoño-Va, I Groisman
Oncotarget, 2020-11-10;11(45):4155-4168.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Preliminary evaluations of 3-dimensional human skin models for their ability to facilitate in vitro the long-term development of the debilitating obligatory human parasite Onchocerca volvulus
Authors: C Malkmus, S Jawahar, N Tricoche, S Lustigman, J Hansmann
PLoS Negl Trop Dis, 2020-11-05;14(11):e0008503.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells
Authors: FJ Hawkins, S Suzuki, ML Beermann, C Barillà, R Wang, C Villacorta, A Berical, JC Jean, J Le Suer, T Matte, C Simone-Roa, Y Tang, TM Schlaeger, AM Crane, N Matthias, SXL Huang, SH Randell, J Wu, JR Spence, G Carraro, BR Stripp, A Rab, EJ Sorsher, A Horani, SL Brody, BR Davis, DN Kotton
Cell Stem Cell, 2020-10-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
Authors: KC Allan, LR Hu, MA Scavuzzo, AR Morton, AS Gevorgyan, EF Cohn, BLL Clayton, IR Bederman, S Hung, CF Bartels, M Madhavan, PJ Tesar
Cell Stem Cell, 2020-10-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks
Authors: KH Elliott, X Chen, J Salomone, P Chaturvedi, PA Schultz, SK Balchand, JD Servetas, A Zuniga, R Zeller, B Gebelein, MT Weirauch, KA Peterson, SA Brugmann
Elife, 2020-10-02;9(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Mesenchymal stem/stromal cell quality control: validation of mixed lymphocyte reaction assay using flow cytometry according to ICH Q2(R1)
Authors: T Nicotra, A Desnos, J Halimi, H Antonot, L Reppel, T Belmas, A Freton, F Stranieri, M Mebarki, J Larghero, A Cras, L Faivre
Stem Cell Res Ther, 2020-10-01;11(1):426.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Efficient Propagation of Circulating Tumor Cells: A First Step for Probing Tumor Metastasis
Authors: J Xiao, JR McGill, K Stanton, JD Kassner, S Choudhury, R Schlegel, ZE Sauna, PR Pohlmann, S Agarwal
Cancers (Basel), 2020-09-28;12(10):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration
Authors: D Garbett, A Bisaria, C Yang, DG McCarthy, A Hayer, WE Moerner, TM Svitkina, T Meyer
Nat Commun, 2020-09-23;11(1):4818.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
Authors: F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen
Res Sq, 2020-09-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hydrogel Network Dynamics Regulate Vascular Morphogenesis
Authors: Z Wei, R Schnellman, HC Pruitt, S Gerecht
Cell Stem Cell, 2020-09-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration
Authors: S Zhou, W Zhang, G Cai, Y Ding, C Wei, S Li, Y Yang, J Qin, D Liu, H Zhang, X Shao, J Wang, H Wang, W Yang, H Wang, S Chen, P Hu, L Sun
Cell Res., 2020-08-24;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Enhancement of cell proliferation and motility of mammalian cells grown in co-culture with Pichia pastoris expressing recombinant human FGF-2
Authors: HHM Le, D Vang, N Amer, T Vue, C Yee, H Kaou, JS Harrison, N Xiao, J Lin-Ceregh, GP Lin-Ceregh, Thor
Protein Expr. Purif., 2020-08-23;176(0):105724.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
A bioenergetic shift is required for spermatogonial differentiation
Authors: W Chen, Z Zhang, C Chang, Z Yang, P Wang, H Fu, X Wei, E Chen, S Tan, W Huang, L Sun, T Ni, Y Yang, Y Wang
Cell Discov, 2020-08-18;6(0):56.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
CHIR99021 and rpIL6 promote porcine parthenogenetic embryo development and blastocyst quality
Authors: SY Yin, BM Sun, T Xu, X Liu, LJ Huo, X Zhang, J Zhou, YL Miao
Theriogenology, 2020-08-17;158(0):470-476.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay -
Atherosclerotic Pre-Conditioning Affects the Paracrine Role of Circulating Angiogenic Cells Ex-Vivo
Authors: S Eslava-Alc, MJ Extremera-, I Sanchez-Go, L Beltrán-Ca, A Rosal-Vela, J Muñoz, N Ibarz, JA Alonso-Piñ, M Rojas-Torr, M Jiménez-Pa, A González-R, R Conejero, E Doiz, M Rodriguez-, R Moreno-Lun, MC Durán-Ruiz
Int J Mol Sci, 2020-07-24;21(15):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Sufficiency for inducible Caspase-9 safety switch in human pluripotent stem cells and disease cells
Authors: T Nishimura, H Xu, M Iwasaki, D Karigane, B Saavedra, Y Takahashi, FP Suchy, S Monobe, RM Martin, M Ohtaka, M Nakanishi, SR Burrows, ML Cleary, R Majeti, A Shibuya, H Nakauchi
Gene Ther., 2020-07-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Antimicrobial activity of mesenchymal stem cells against Staphylococcus aureus
Authors: H Yagi, AF Chen, D Hirsch, AC Rothenberg, J Tan, PG Alexander, RS Tuan
Stem Cell Res Ther, 2020-07-17;11(1):293.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance
Authors: CE Eyler, H Matsunaga, V Hovestadt, SJ Vantine, P van Galen, BE Bernstein
Genome Biol., 2020-07-15;21(1):174.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Astrocytes influence medulloblastoma phenotypes and CD133 surface expression
Authors: E Gronseth, A Gupta, C Koceja, S Kumar, RG Kutty, K Rarick, L Wang, R Ramchandra
PLoS ONE, 2020-07-06;15(7):e0235852.
Species: Zebrafish
Sample Types: Whole Cells
Applications: Cell Culture -
Indonesian Ginger (Bangle) Extract Promotes Neurogenesis of Human Neural Stem Cells through WNT Pathway Activation
Authors: K Hirano, M Kubo, Y Fukuyama, M Namihira
Int J Mol Sci, 2020-07-05;21(13):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
NRF2 Knockdown Resensitizes 5-Fluorouracil-Resistant Pancreatic Cancer Cells by Suppressing HO-1 and ABCG2 Expression
Authors: EJ Kim, YJ Kim, HI Lee, SH Jeong, HJ Nam, JH Cho
Int J Mol Sci, 2020-06-30;21(13):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
Authors: LTP Khoa, YC Tsan, F Mao, DM Kremer, P Sajjakulnu, L Zhang, B Zhou, X Tong, NV Bhanu, C Choudhary, BA Garcia, L Yin, GD Smith, TL Saunders, SL Bielas, CA Lyssiotis, Y Dou
Cell Stem Cell, 2020-06-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020-06-19;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis
Authors: J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang, C Feng, T Gao, Y Chen, Y Li, Z Wang, J Wen, S Yang, P Liu, L Wang, Y Wang, L Peng, GN Stacey, Z Hu, G Feng, W Li, Y Huo, R Jin, N Shyh-Chang, Q Zhou, L Wang, B Hu, H Dai, J Hao
Cell Res., 2020-06-16;0(0):.
Species: Human
Sample Types: Embryoid Bodies
Applications: Bioassay -
Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature
Authors: BN Sheikh, S Guhathakur, TH Tsang, M Schwabenla, G Renschler, B Herquel, V Bhardwaj, H Holz, T Stehle, O Bondareva, N Aizarani, O Mossad, O Kretz, W Reichardt, A Chatterjee, LJ Braun, J Thevenon, H Sartelet, T Blank, D Grün, D von Elverf, TB Huber, D Vestweber, S Avilov, M Prinz, JM Buescher, A Akhtar
Nat. Cell Biol., 2020-06-15;0(0):.
Species: Mouse
Sample Types: Organoid
Applications: Bioassay -
Galectin-3 diminishes Wnt signaling in the postnatal subventricular zone
Authors: O Al-Dalahma, J Nicholson, S Draijer, LC Soares, FG Szele
Stem Cells, 2020-06-08;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models
Authors: JA Gregory, E Hoelzli, R Abdelaal, C Braine, M Cuevas, M Halpern, N Barretto, N Schrode, G Akbalik, K Kang, E Cheng, K Bowles, S Lotz, S Goderie, CM Karch, S Temple, A Goate, KJ Brennand, H Phatnani
Cells, 2020-06-05;9(6):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
Authors: J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomano, A Zviran, AG Deslaurier, N Dusaj, SD Nimer, C Leslie, DA Landau, MG Kharas, EP Papapetrou
Cell Rep, 2020-06-02;31(9):107688.
Species: Human
Sample Types:
Applications: Cell Culture -
Efficient Cardiac Differentiation of Human Amniotic Fluid-Derived Stem Cells into Induced Pluripotent Stem Cells and Their Potential Immune Privilege
Authors: YH Fang, SPH Wang, ZH Gao, SN Wu, HY Chang, PJ Yang, PY Liu, YW Liu
Int J Mol Sci, 2020-03-29;21(7):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection
Authors: SK Ryan, MV Gonzalez, JP Garifallou, FC Bennett, KS Williams, NP Sotuyo, E Mironets, K Cook, H Hakonarson, SA Anderson, KL Jordan-Sci
Stem Cell Reports, 2020-03-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation
Authors: L Nimtz, J Hartmann, J Tigges, S Masjosthus, M Schmuck, E Ke beta el, S Theiss, K Köhrer, P Petzsch, J Adjaye, C Wigmann, D Wieczorek, B Hildebrand, F Bendt, U Hübenthal, G Brockerhof, E Fritsche
Stem Cell Res, 2020-03-10;45(0):101761.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives
Authors: HY Jo, HW Han, I Jung, JH Ju, SJ Park, S Moon, D Geum, H Kim, HJ Park, S Kim, GN Stacey, SK Koo, MH Park, JH Kim
Sci Rep, 2020-03-03;10(1):3939.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter
Authors: A Dicks, CL Wu, N Steward, SS Adkar, CA Gersbach, F Guilak
Stem Cell Res Ther, 2020-02-18;11(1):66.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
ER stress reliever enhances functionalities of in vitro cultured hepatocytes
Authors: JS Kim, SI Hwang, JL Ryu, HS Hong, JM Lee, SM Lee, X Jin, C Han, JH Kim, J Han, MR Lee, DH Woo
Stem Cell Res, 2020-02-12;43(0):101732.
Species: Human
Sample Types: cell culture
-
Antagonizing binding of cell cycle and apoptosis regulatory protein 1 (CARP-1) to the NEMO/IKKgamma protein enhances the anticancer effect of chemotherapy
Authors: J Venkatesh, SC Sekhar, VT Cheriyan, M Muthu, P Meister, E Levi, S Dzinic, JW Gauld, LA Polin, AK Rishi
J. Biol. Chem., 2020-02-04;295(11):3532-3552.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CLEC14A deficiency exacerbates neuronal loss by increasing blood-brain barrier permeability and inflammation
Authors: Y Kim, S Lee, H Zhang, S Lee, H Kim, Y Kim, MH Won, YM Kim, YG Kwon
J Neuroinflammation, 2020-02-04;17(1):48.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition
Authors: M Oatley, ÖV Bölükbas?, V Svensson, M Shvartsman, K Ganter, K Zirngibl, PV Pavlovich, V Milchevska, V Foteva, KN Natarajan, B Baying, V Benes, KR Patil, SA Teichmann, C Lancrin
Nat Commun, 2020-01-29;11(1):586.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells
Authors: AR Nickolls, MM Lee, DF Espinoza, M Szczot, RM Lam, Q Wang, J Beers, J Zou, MQ Nguyen, HJ Solinski, AA AlJanahi, KR Johnson, ME Ward, AT Chesler, CG Bönnemann
Cell Rep, 2020-01-21;30(3):932-946.e7.
Species: Human
Sample Types: Whole Cells
Applications: Dififerentiation -
NeuroCore formation during differentiation of neurospheres of mouse embryonic neural stem cells
Authors: JH Lee, MR Shaker, E Lee, B Lee, W Sun
Stem Cell Res, 2020-01-18;43(0):101691.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Silencing of AURKA augments the antitumor efficacy of the AURKA inhibitor MLN8237 on neuroblastoma cells
Authors: Y Yang, L Ding, Q Zhou, L Fen, Y Cao, J Sun, X Zhou, A Liu
Cancer Cell Int., 2020-01-07;20(0):9.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition
Authors: Z Chen, J Zhang, H Xue, M Qian, X Guo, X Gao, J Xu, Y Qi, X Sun, G Li
Integr Cancer Ther, 2020-01-01;19(0):1534735419900.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Authors: L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen
Cell Stem Cell, 2020;27(1):125-136.e7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity
Authors: D Suzuki, C Flahou, N Yoshikawa, I Stirblyte, Y Hayashi, A Sawaguchi, M Akasaka, S Nakamura, N Higashi, H Xu, T Matsumoto, K Fujio, MG Manz, A Hotta, H Takizawa, K Eto, N Sugimoto
Stem Cell Reports, 2019-12-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors
Authors: D Chen, N Sun, L Hou, R Kim, J Faith, M Aslanyan, Y Tao, Y Zheng, J Fu, W Liu, M Kellis, A Clark
Cell Rep, 2019-12-24;29(13):4568-4582.e5.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
GDNF and GFRalpha1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons
Authors: A Bonafina, MF Trinchero, AS Ríos, P Bekinschte, AF Schinder, G Paratcha, F Ledda
Cell Rep, 2019-12-24;29(13):4308-4319.e4.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture -
The oncogenic and druggable hPG80 (Progastrin) is overexpressed in multiple cancers and detected in the blood of patients
Authors: B You, F Mercier, E Assenat, C Langlois-J, O Glehen, J Soulé, L Payen, V Kepenekian, M Dupuy, F Belouin, E Morency, V Saywell, M Flacelière, P Elies, P Liaud, T Mazard, D Maucort-Bo, W Tan, B Vire, L Villeneuve, M Ychou, M Kohli, D Joubert, A Prieur
EBioMedicine, 2019-12-24;51(0):102574.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma
Authors: C Fisher, G Obaid, C Niu, W Foltz, A Goldstein, T Hasan, L Lilge
J Clin Med, 2019-12-14;8(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neurospheres induced from human adipose-derived stem cells as a new source of neural progenitor cells
Authors: C Peng, L Lu, Y Li, J Hu
Cell Transplant, 2019-12-08;0(0):9636897198886.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies
Authors: M Ali, F Kabir, JJ Thomson, Y Ma, C Qiu, M Delannoy, SY Khan, SA Riazuddin
Sci Rep, 2019-12-06;9(1):18552.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo
Authors: S Weber, SE Koschade, CM Hoffmann, TD Dubash, KM Giessler, SM Dieter, F Herbst, H Glimm, CR Ball
BMC Cancer, 2019-12-03;19(1):1181.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering
Authors: D Hao, C He, B Ma, L Lankford, L Reynaga, DL Farmer, F Guo, A Wang
Stem Cells Int, 2019-11-12;2019(0):9695239.
Species: Human
Sample Types: Whole Tissue
Applications: Tissue Culture -
Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix
Authors: M Vermeulen, F Del Vento, M Kanbar, S Pyr Dit Ru, D Vertommen, J Poels, C Wyns
Int J Mol Sci, 2019-11-03;20(21):.
Species: Porcine
Sample Types: Organoid
Applications: Bioassay -
Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination
Authors: A Tripathi, C Volsko, JP Garcia, E Agirre, KC Allan, PJ Tesar, BD Trapp, G Castelo-Br, FJ Sim, R Dutta
Cell Rep, 2019-10-22;29(4):904-919.e9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion
Authors: J Chen, B Ananthanar, KS Springer, KJ Wolf, SM Sheyman, VD Tran, S Kumar
Cancer Res., 2019-10-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus
Authors: Y Koutmani, IA Gampieraki, A Polissidis, M Ximerakis, PN Koutsoudak, A Polyzos, G Agrogianni, S Karaliota, D Thomaidou, LL Rubin, PK Politis, KP Karalis
Cell Rep, 2019-10-22;29(4):932-945.e7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction
Authors: F Inoue, A Kreimer, T Ashuach, N Ahituv, N Yosef
Cell Stem Cell, 2019-10-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals
Authors: T Yung, F Poon, M Liang, S Coquenlorg, EC McGaugh, CC Hui, MD Wilson, MC Nostro, TH Kim
Nat Commun, 2019-10-11;10(1):4647.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human amniotic mesenchymal stem cells improve the follicular microenvironment to recover ovarian function in premature ovarian failure mice
Authors: R Liu, X Zhang, Z Fan, Y Wang, G Yao, X Wan, Z Liu, B Yang, L Yu
Stem Cell Res Ther, 2019-10-02;10(1):299.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas
Authors: T Tabata, M Petitt, J Fang-Hoove, DC Freed, F Li, Z An, D Wang, TM Fu, L Pereira
Vaccines (Basel), 2019-09-29;7(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Manipulating energy migration within single lanthanide activator for switchable upconversion emissions towards bidirectional photoactivation
Authors: Q Mei, A Bansal, MKG Jayakumar, Z Zhang, J Zhang, H Huang, D Yu, CJA Ramachandr, DJ Hausenloy, TW Soong, Y Zhang
Nat Commun, 2019-09-27;10(1):4416.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure
Authors: V Lungova, X Chen, Z Wang, C Kendziorsk, SL Thibeault
Nat Commun, 2019-09-24;10(1):4161.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
HIV-1 Tat protein inhibits the hematopoietic support function of human bone marrow mesenchymal stem cells
Authors: Y Yuan, C Zhou, Q Yang, S Ma, X Wang, X Guo, Y Ding, J Tang, Y Zeng, D Li
Virus Res., 2019-09-12;273(0):197756.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison
Authors: KM Walter, K Dach, K Hayakawa, S Giersiefer, H Heuer, PJ Lein, E Fritsche
PLoS ONE, 2019-09-12;14(9):e0221230.
Species: Human, Rat
Sample Types: Whole Cells
Applications: Bioassay -
Differentially Expressed microRNAs in MIA PaCa-2 and PANC-1 Pancreas Ductal Adenocarcinoma Cell Lines are Involved in Cancer Stem Cell Regulation
Authors: Y Shen, K Pu, K Zheng, X Ma, J Qin, L Jiang, J Li
Int J Mol Sci, 2019-09-10;20(18):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms
Authors: V Ravi, AB Madhankuma, T Abraham, B Slagle-Web, JR Connor
PLoS ONE, 2019-09-06;14(9):e0221952.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of Best disease-derived induced pluripotent stem cell line (FRIMOi006-A) carrying a novel dominant mutation in BEST1 gene
Authors: J Domingo-Pr, M Riera, V Abad-Moral, S Ruiz-Nogal, B Corcostegu, E Pomares
Stem Cell Res, 2019-09-04;40(0):101570.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Generation of an induced pluripotent stem cell line (FRIMOi007-A) derived from an incomplete achromatopsia patient carrying a novel homozygous mutation in PDE6C gene
Authors: J Domingo-Pr, V Abad-Moral, M Riera, R Navarro, B Corcostegu, E Pomares
Stem Cell Res, 2019-09-04;40(0):101569.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy
Authors: SP Hong, TE Chan, Y Lombardo, G Corleone, N Rotmensz, S Bravaccini, A Rocca, G Pruneri, KR McEwen, RC Coombes, I Barozzi, L Magnani
Nat Commun, 2019-09-02;10(1):3840.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Neurobiological roots of psychopathy
Authors: J Tiihonen, M Koskuvi, M Lähteenvuo, PLJ Virtanen, I Ojansuu, O Vaurio, Y Gao, I Hyötyläine, KA Puttonen, E Repo-Tiiho, T Paunio, MR Rautiainen, S Tyni, J Koistinaho, Š Lehtonen
Mol. Psychiatry, 2019-08-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
High Expression of Acid-Sensing Ion Channel 2 (ASIC2) in Bone Cells in Osteoporotic Vertebral Fractures
Authors: CY Lee, TJ Huang, MH Wu, YY Li, KD Lee
Biomed Res Int, 2019-08-19;2019(0):4714279.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Real-time PCR quantification of spliced X-box binding protein 1 (XBP1) using a universal primer method
Authors: SB Yoon, YH Park, SA Choi, HJ Yang, PS Jeong, JJ Cha, S Lee, SH Lee, JH Lee, BW Sim, BS Koo, SJ Park, Y Lee, YH Kim, JJ Hong, JS Kim, YB Jin, JW Huh, SR Lee, BS Song, SU Kim
PLoS ONE, 2019-07-22;14(7):e0219978.
Species: Bovine, Macaca fascicularis (cynomolgus monkey), Mouse, Porcine
Sample Types: Whole Cells
Applications: Cell Culture -
Nanomedicine-based Curcumin Approach Improved ROS Damage in Best Dystrophy-specific Induced Pluripotent Stem Cells
Authors: TC Lin, YY Lin, CC Hsu, YP Yang, CH Yang, DK Hwang, CY Wang, YY Liu, WL Lo, SH Chiou, CH Peng, SJ Chen, YL Chang
Cell Transplant, 2019-07-17;0(0):9636897198601.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human iPS cell-derived engineered heart tissue does not affect ventricular arrhythmias in a guinea pig cryo-injury model
Authors: S Pecha, K Yorgan, M Röhl, B Geertz, A Hansen, F Weinberger, S Sehner, H Ehmke, H Reichenspu, T Eschenhage, AP Schwoerer
Sci Rep, 2019-07-08;9(1):9831.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation
Authors: L Messerschm, S Fischer, P Wiedemann, A Bringmann, M Hollborn
Mol. Vis., 2019-06-30;25(0):329-344.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of two human iPSC lines (MDCUi001-A and MDCUi001-B) from dermal fibroblasts of a Thai patient with X-linked osteogenesis imperfecta using integration-free Sendai virus
Authors: S Tongkobpet, R Rungsiwiwu, K Pruksanano, K Suphapeeti, V Shotelersu
Stem Cell Res, 2019-06-29;39(0):101493.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
ZIC3 Controls the Transition from Naive to Primed Pluripotency
Authors: SH Yang, M Andrabi, R Biss, S Murtuza Ba, M Iqbal, AD Sharrocks
Cell Rep, 2019-06-11;27(11):3215-3227.e6.
Species: Mouse
Sample Types: Transfected Whole Cells
Applications: Bioassay -
Establishment of an induced pluripotent stem cell line (FRIMOi005-A) derived from a retinitis pigmentosa patient carrying a dominant mutation in RHO gene
Authors: J Domingo-Pr, M Riera, A Burés-Jels, B Corcostegu, E Pomares
Stem Cell Res, 2019-05-22;38(0):101468.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons
Authors: M Meijer, K Rehbach, JW Brunner, JA Classen, HCA Lammertse, LA van Linge, D Schut, T Krutenko, M Hebisch, LN Cornelisse, PF Sullivan, M Peitz, RF Toonen, O Brüstle, M Verhage
Cell Rep, 2019-05-14;27(7):2199-2211.e6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD
Authors: N Kawai, Y Hirohashi, Y Ebihara, T Saito, A Murai, T Saito, T Shirosaki, T Kubo, M Nakatsugaw, T Kanaseki, T Tsukahara, T Shichinohe, L Li, S Hirano, T Torigoe
PLoS ONE, 2019-05-13;14(5):e0216503.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Immunomodulation with Human Umbilical Cord Blood Stem Cells Ameliorates Ischemic Brain Injury - A Brain Transcriptome Profiling Analysis
Authors: ML Shiao, C Yuan, AT Crane, JP Voth, M Juliano, LLH Stone, Z Nan, Y Zhang, N Kuzmin-Nic, PR Sanberg, AW Grande, WC Low
Cell Transplant, 2019-05-08;0(0):9636897198367.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
RUNX represses Pmp22 to drive neurofibromagenesis
Authors: A Hall, K Choi, W Liu, J Rose, C Zhao, Y Yu, Y Na, Y Cai, RA Coover, Y Lin, E Dombi, M Kim, D Levanon, Y Groner, E Boscolo, D Pan, PP Liu, QR Lu, N Ratner, G Huang, J Wu
Sci Adv, 2019-04-24;5(4):eaau8389.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Development of a Cx46 Targeting Strategy for Cancer Stem Cells
Authors: EE Mulkearns-, LA Torre-Heal, DJ Silver, JT Eurich, D Bayik, E Serbinowsk, M Hitomi, J Zhou, B Przychodze, R Zhang, SA Sprowls, JS Hale, TJ Alban, A Berezovsky, BA Bell, PR Lockman, BK Jha, JD Lathia
Cell Rep, 2019-04-23;27(4):1062-1072.e5.
Species: Xenograft
Sample Types: Whole Cells
Applications: Bioassay -
Co-Transplantation of Human Umbilical Cord Mesenchymal Stem Cells and Human Neural Stem Cells Improves the Outcome in Rats with Spinal Cord Injury
Authors: L Sun, F Wang, H Chen, D Liu, T Qu, X Li, D Xu, F Liu, Z Yin, Y Chen
Cell Transplant, 2019-04-23;0(0):9636897198445.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
PTPRK suppresses progression and chemo-resistance of colon cancer cells via direct inhibition of pro-oncogenic CD133
Authors: M Matsushita, Y Mori, K Uchiumi, T Ogata, M Nakamura, H Yoda, H Soda, N Takiguchi, Y Nabeya, O Shimozato, T Ozaki
FEBS Open Bio, 2019-04-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Organoid culture media formulated with growth factors of defined cellular activity
Authors: M Urbischek, H Rannikmae, T Foets, K Ravn, M Hyvönen, M de la Roch
Sci Rep, 2019-04-17;9(1):6193.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells
Authors: G MacLeod, DA Bozek, N Rajakulend, V Monteiro, M Ahmadi, Z Steinhart, MM Kushida, H Yu, FJ Coutinho, FMG Cavalli, I Restall, X Hao, T Hart, HA Luchman, S Weiss, PB Dirks, S Angers
Cell Rep, 2019-04-16;27(3):971-986.e9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness
Authors: SFB Fadhlullah, NBA Halim, JYT Yeo, RLY Ho, P Um, BT Ang, C Tang, WH Ng, DM Virshup, IAW Ho
Oncogene, 2019-04-09;38(27):5367-5380.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
Cell Rep, 2019-04-09;27(2):599-615.e12.
Species: Human
Sample Types: cell culture
Applications: Differentiation, Differentiation -
Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation
Authors: S Varum, A Baggiolini, L Zurkirchen, ZK Atak, C Cantù, E Marzorati, R Bossart, J Wouters, J Häusel, E Tuncer, D Zingg, D Veen, N John, M Balz, MP Levesque, K Basler, S Aerts, N Zamboni, R Dummer, L Sommer
Cell Stem Cell, 2019-04-04;24(4):637-653.e9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PTH decreases in vitro human cartilage regeneration without affecting hypertrophic differentiation
Authors: M Rutgers, F Bach, L Vonk, M van Rijen, V Akrum, A van Boxtel, W Dhert, L Creemers
PLoS ONE, 2019-04-04;14(4):e0213483.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Derivation of enteric neuron lineages from human pluripotent stem cells
Authors: K Barber, L Studer, F Fattahi
Nat Protoc, 2019-03-25;14(4):1261-1279.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Microelectrode Array With Transparent ALD TiN Electrodes
Authors: T Ryynänen, A Pelkonen, K Grigoras, OME Ylivaara, T Hyvärinen, J Ahopelto, M Prunnila, S Narkilahti, J Lekkala
Front Neurosci, 2019-03-22;13(0):226.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularisation
Authors: S Ashraf, S Bell, C O'Leary, P Canning, I Micu, JA Fernandez, M O'Hare, P Barabas, H McCauley, DP Brazil, AW Stitt, JG McGeown, TM Curtis
JCI Insight, 2019-03-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
AKT drives SOX2 overexpression and cancer cell stemness in esophageal cancer by protecting SOX2 from UBR5-mediated degradation
Authors: Z Wang, L Kang, H Zhang, Y Huang, L Fang, M Li, PJ Brown, CH Arrowsmith, J Li, J Wong
Oncogene, 2019-03-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
MKP-4 suppresses hepatocarcinogenesis by targeting ERK1/2 pathway
Authors: Z Shen, C Zhang, L Qu, C Lu, M Xiao, R Ni, J Liu
Cancer Cell Int., 2019-03-18;19(0):61.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death
Authors: MA Ajmone-Cat, A Onori, C Toselli, E Stronati, M Morlando, I Bozzoni, E Monni, Z Kokaia, G Lupo, L Minghetti, S Biagioni, E Cacci
Sci Rep, 2019-03-14;9(1):4572.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4
Authors: N Funk, M Munz, T Ott, K Brockmann, A Wenninger-, R Kühn, D Vogt-Weise, F Giesert, W Wurst, T Gasser, S Biskup
Sci Rep, 2019-03-14;9(1):4515.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
Cell Stem Cell, 2019-03-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Isolation and characterization of myogenic precursor cells from human cremaster muscle
Authors: N Naldaiz-Ga, M Goicoechea, IM Aragón, V Pérez-Lópe, S Fuertes-Al, B Herrera-Im, A López de M, R de Luna-Di, PM Baptista, MA Fernández, MF Lara, A Izeta
Sci Rep, 2019-03-05;9(1):3454.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
c-Myc maintains the self-renewal and chemoresistance properties of colon cancer stem cells
Authors: HL Zhang, P Wang, MZ Lu, SD Zhang, L Zheng
Oncol Lett, 2019-02-28;17(5):4487-4493.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids
Authors: YP Xu, Y Qiu, B Zhang, G Chen, Q Chen, M Wang, F Mo, J Xu, J Wu, RR Zhang, ML Cheng, NN Zhang, B Lyu, WL Zhu, MH Wu, Q Ye, D Zhang, JH Man, XF Li, J Cui, Z Xu, B Hu, X Zhou, CF Qin
Cell Res., 2019-02-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects
Authors: J Ooi, SR Langley, X Xu, KH Utami, B Sim, Y Huang, NP Harmston, YL Tay, A Ziaei, R Zeng, D Low, F Aminkeng, RM Sobota, F Ginhoux, E Petretto, MA Pouladi
Cell Rep, 2019-02-26;26(9):2494-2508.e7.
-
Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming
Authors: N Muraoka, K Nara, F Tamura, H Kojima, H Yamakawa, T Sadahiro, K Miyamoto, M Isomi, S Haginiwa, H Tani, S Kurotsu, R Osakabe, S Torii, S Shimizu, H Okano, Y Sugimoto, K Fukuda, M Ieda
Nat Commun, 2019-02-20;10(1):674.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase
Authors: M Kunova Bos, A Nita, T Gregor, M Varecha, I Gudernova, B Fafilek, T Barta, N Basheer, SP Abraham, L Balek, M Tomanova, J Fialova Ku, J Bosak, D Potesil, J Zieba, J Song, P Konik, S Park, I Duran, Z Zdrahal, D Smajs, G Jansen, Z Fu, HW Ko, A Hampl, L Trantirek, D Krakow, P Krejci
Proc. Natl. Acad. Sci. U.S.A., 2019-02-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of two iPS cell lines (FRIMOi003-A and FRIMOi004-A) derived from Stargardt patients carrying ABCA4 compound heterozygous mutations
Authors: M Riera, A Patel, A Burés-Jels, B Corcostegu, S Chang, E Pomares, B Corneo, JR Sparrow
Stem Cell Res, 2019-02-13;36(0):101389.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
Authors: E Ito, S Miyagawa, M Takeda, A Kawamura, A Harada, H Iseoka, S Yajima, N Sougawa, N Mochizuki-, S Yasuda, Y Sato, Y Sawa
Sci Rep, 2019-02-13;9(1):1881.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Combined prognostic value of the cancer stem cell markers CD47 and CD133 in esophageal squamous cell carcinoma
Authors: JH Wang, ST Huang, L Zhang, ZG Liu, RX Liang, SW Jiang, YN Jiang, XJ Yu, YC Jiang, XZ Li, PF Zhang, ZS Wen, M Zheng
Cancer Med, 2019-02-11;0(0):.
Species: Human
Sample Types:
Applications: Bioassay -
CIC protein instability contributes to tumorigenesis in glioblastoma
Authors: S Bunda, P Heir, J Metcalf, ASC Li, S Agnihotri, S Pusch, M Yasin, M Li, K Burrell, S Mansouri, O Singh, M Wilson, A Alamsahebp, R Nejad, B Choi, D Kim, A von Deimli, G Zadeh, K Aldape
Nat Commun, 2019-02-08;10(1):661.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Novel Gastric Cancer Stem Cell-Related Marker LINGO2 Is Associated with Cancer Cell Phenotype and Patient Outcome
Authors: JH Jo, SB Park, S Park, HS Lee, C Kim, DE Jung, SY Song
Int J Mol Sci, 2019-01-28;20(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells
Authors: A Montel-Hag, CS Seet, S Li, B Chick, Y Zhu, P Chang, S Tsai, V Sun, S Lopez, HC Chen, C He, CJ Chin, D Casero, GM Crooks
Cell Stem Cell, 2019-01-17;0(0):.
Applications: Bioassay -
Establishment and characterization of an iPSC line (FRIMOi001-A) derived from a retinitis pigmentosa patient carrying PDE6A mutations
Authors: M Riera, A Patel, B Corcostegu, S Chang, JR Sparrow, E Pomares, B Corneo
Stem Cell Res, 2019-01-17;35(0):101385.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of an induced pluripotent stem cell line (FRIMOi002-A) from a retinitis pigmentosa patient carrying compound heterozygous mutations in USH2A gene
Authors: M Riera, A Patel, B Corcostegu, S Chang, B Corneo, JR Sparrow, E Pomares
Stem Cell Res, 2019-01-17;35(0):101386.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Serum-Free Manufacturing of Mesenchymal Stem Cell Tissue Rings Using Human-Induced Pluripotent Stem Cells
Authors: TS Winston, K Suddhapas, C Wang, R Ramos, P Soman, Z Ma
Stem Cells Int, 2019-01-15;2019(0):5654324.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Metformin Results in Diametrically Opposed Effects by Targeting Non-Stem Cancer Cells but Protecting Cancer Stem Cells in Head and Neck Squamous Cell Carcinoma
Authors: SZ Kuo, CO Honda, WT Li, TK Honda, E Kim, X Altuna, E Abhold, J Wang-Rodri, WM Ongkeko
Int J Mol Sci, 2019-01-07;20(1):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dosage time affects alkylating agents induced micronuclei in mouse peripheral blood reticulocytes through the function of erythropoietin
Authors: K Itoh, S Masumori, D Mukai, H Sakakibara, M Yasuda, K Shimoi
J Toxicol Sci, 2019-01-01;44(4):273-282.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation
Authors: D Chen, W Liu, J Zimmerman, WA Pastor, R Kim, L Hosohama, J Ho, M Aslanyan, JJ Gell, SE Jacobsen, AT Clark
Cell Rep, 2018-12-26;25(13):3591-3602.e5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Reliability of human cortical organoid generation
Authors: SJ Yoon, LS Elahi, AM Pa?ca, RM Marton, A Gordon, O Revah, Y Miura, EM Walczak, GM Holdgate, HC Fan, JR Huguenard, DH Geschwind, SP Pa?ca
Nat. Methods, 2018-12-20;16(1):75-78.
Species: Human
Sample Types: Organoids
Applications: Bioassay -
Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene
Authors: JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French
Stem Cell Res, 2018-12-10;34(0):101361.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Antibody-mediated delivery of VEGF-C potently reduces chronic skin inflammation
Authors: S Schwager, S Renner, T Hemmerle, S Karaman, ST Proulx, R Fetz, AM Golding-Oc, P Probst, C Halin, D Neri, M Detmar
JCI Insight, 2018-12-06;3(23):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Additive effect of bFGF and selenium on expansion and paracrine action of human amniotic fluid-derived mesenchymal stem cells
Authors: J Park, JH Lee, BS Yoon, EK Jun, G Lee, IY Kim, S You
Stem Cell Res Ther, 2018-11-08;9(1):293.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
BMI1 enables interspecies chimerism with human pluripotent stem cells
Authors: K Huang, Y Zhu, Y Ma, B Zhao, N Fan, Y Li, H Song, S Chu, Z Ouyang, Q Zhang, Q Xing, C Lai, N Li, T Zhang, J Gu, B Kang, Y Shan, K Lai, W Huang, Y Mai, Q Wang, J Li, A Lin, Y Zhang, X Zhong, B Liao, L Lai, J Chen, D Pei, G Pan
Nat Commun, 2018-11-07;9(1):4649.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Involvement of the capsular GalXM-induced IL-17 cytokine in the control of Cryptococcus neoformans infection
Authors: IF LaRocque-d, JDB Rocha, MP Nunes, PAV Oliveira, DO Nascimento, L Freire-de-, CM Takiya, A Morrot, D Decote-Ric, JO Previato, GA DosReis, L Mendonça-P, CG Freire-de-
Sci Rep, 2018-11-06;8(1):16378.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
VGF nerve growth factor inducible is involved in retinal ganglion cells death induced by optic nerve crush
Authors: H Takeuchi, S Inagaki, W Morozumi, Y Nakano, Y Inoue, Y Kuse, T Mizoguchi, S Nakamura, M Funato, H Kaneko, H Hara, M Shimazawa
Sci Rep, 2018-11-06;8(1):16443.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing
Authors: SS Adkar, CL Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, F Guilak
Stem Cells, 2018-10-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Optimized Clump Culture Methods for Adult Human Multipotent Neural Cells
Authors: JY Yeon, JY Hwang, HW Lee, HJ Pyeon, JS Won, YJ Noh, H Nam, KM Joo
Int J Mol Sci, 2018-10-29;19(11):.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay -
Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
Authors: B Readhead, BJ Hartley, BJ Eastwood, DA Collier, D Evans, R Farias, C He, G Hoffman, P Sklar, JT Dudley, EE Schadt, R Savi?, KJ Brennand
Nat Commun, 2018-10-24;9(1):4412.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype
Authors: A Omer Javed, Y Li, J Muffat, KC Su, MA Cohen, T Lungjangwa, P Aubourg, IM Cheeseman, R Jaenisch
Cell Rep, 2018-10-09;25(2):368-382.e5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling
Authors: Y Zhang, Y Yang, M Jiang, SX Huang, W Zhang, D Al Alam, S Danopoulos, M Mori, YW Chen, R Balasubram, SM Chuva de S, C Serra, M Bialecka, E Kim, S Lin, ALR Toste de C, PN Riccio, WV Cardoso, X Zhang, HW Snoeck, J Que
Cell Stem Cell, 2018-09-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation and assembly of human brain region-specific three-dimensional cultures
Authors: SA Sloan, J Andersen, AM Pa?ca, F Birey, SP Pa?ca
Nat Protoc, 2018-09-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
High NRF2 level mediates cancer stem cell-like properties of aldehyde dehydrogenase�(ALDH)-high ovarian cancer cells: inhibitory role of all-trans retinoic acid in ALDH/NRF2 signaling
Authors: D Kim, BH Choi, IG Ryoo, MK Kwak
Cell Death Dis, 2018-08-30;9(9):896.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer
Authors: LS Pane, FG Fulcoli, A Cirino, A Altomonte, R Ferrentino, M Bilio, A Baldini
Dis Model Mech, 2018-08-30;11(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Noncoding RNA Transcripts during Differentiation of Induced Pluripotent Stem Cells into Hepatocytes
Authors: A Skrzypczyk, S Kehr, I Krystel, SH Bernhart, S Giri, A Bader, PF Stadler
Stem Cells Int, 2018-08-19;2018(0):5692840.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ
Authors: Z Liu, Y Wei, L Zhang, PP Yee, M Johnson, X Zhang, M Gulley, JM Atkinson, M Trebak, HG Wang, W Li
Oncogene, 2018-08-06;38(1):120-139.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Streptozotocin-induced ?-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain
Authors: P Nikolakopo, A Chatzigeor, I Kourtzelis, L Toutouna, J Masjkur, C Arps-Forke, SW Poser, J Rozman, B Rathkolb, JA Aguilar-Pi, E Wolf, M Klingenspo, M Ollert, C Schmidt-We, H Fuchs, V Gailus-Dur, M Hrabe de A, V Tsata, LS Monasor, M Troullinak, A Witt, V Anastasiou, G Chrousos, CX Yi, C García-Các, MH Tschöp, SR Bornstein, A Androutsel
Sci Rep, 2018-07-27;8(1):11335.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
Authors: Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, HE Shick, E Garrison, M T Karl, DC Factor, ZS Nevin, JL Sax, MA Thompson, Y Fedorov, J Jin, WK Wilson, M Giera, F Bracher, RH Miller, PJ Tesar, DJ Adams
Nature, 2018-07-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury
Authors: KH Lee, HJ Pyeon, H Nam, JS Won, JY Hwang, KA Lee, JY Yeon, SC Hong, DH Nam, K Lee, SH Lee, KM Joo
Stem Cell Res, 2018-07-19;31(0):71-78.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Segmental Additive Tissue Engineering
Authors: M Sladkova, R Alawadhi, R Jaragh Alh, A Esmael, S Alansari, M Saad, J Mulla Yous, L Alqaoud, GM de Peppo
Sci Rep, 2018-07-18;8(1):10895.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Skeletal Muscle Stem Cells from PSC-Derived Teratomas Have Functional Regenerative Capacity
Authors: SS Chan, RW Arpke, A Filareto, N Xie, MP Pappas, JS Penaloza, RCR Perlingeir, M Kyba
Cell Stem Cell, 2018-07-05;23(1):74-85.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Acoustic waves improves retroviral transduction in human retinal stem cells
Authors: CH Peng, LC Woung, KH Lu, CY Tsai, SD Lee, CS Huang, TC Lin, KH Chien, DK Hwang
J Chin Med Assoc, 2018-06-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages
Authors: J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao
Cell Transplant, 2018-06-13;0(0):9636897187803.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function
Authors: K Skrzypek, A Kusienicka, E Trzyna, B Szewczyk, A Ulman, P Konieczny, T Adamus, B Badyra, M Kortylewsk, M Majka
Cell Death Dis, 2018-05-29;9(6):643.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Oxidation Prevents HMGB1 Inhibition on PDGF-Induced Differentiation of Multipotent Vascular Stem Cells to Smooth Muscle Cells: A Possible Mechanism Linking Oxidative Stress to Atherosclerosis
Authors: X Meng, W Su, X Tao, M Sun, R Ying, W Wei, B Wang
Biomed Res Int, 2018-05-23;2018(0):4019814.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
Authors: X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang
Cell Stem Cell, 2018-05-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis
Authors: LR Penke, JM Speth, VL Dommeti, ES White, IL Bergin, M Peters-Gol
J. Clin. Invest., 2018-05-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors
Authors: B Roy, S Venkatacha, P Ratna, Y Wang, DS Jokhun, M Nagarajan, GV Shivashank
Proc. Natl. Acad. Sci. U.S.A., 2018-05-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction
Authors: M Li, D Khong, LY Chin, A Singleton, B Parekkadan
Sci Rep, 2018-05-01;8(1):6816.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance
Authors: IG Ryoo, BH Choi, SK Ku, MK Kwak
Redox Biol, 2018-04-26;17(0):246-258.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
DNA topoisomerase II? stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression
Authors: M Zaim, S Isik
Stem Cell Res Ther, 2018-04-25;9(1):114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Brain and spinal cord injury repair by implantation of human neural progenitor cells seeded onto polymer scaffolds
Authors: JE Shin, K Jung, M Kim, K Hwang, H Lee, IS Kim, BH Lee, IS Lee, KI Park
Exp. Mol. Med., 2018-04-20;50(4):39.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage
Authors: V Pursani, D Bhartiya, V Tanavde, M Bashir, P Sampath
Stem Cell Res Ther, 2018-04-10;9(1):97.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TNF-? induces human neural progenitor cell survival after oxygen-glucose deprivation by activating the NF-?B pathway
Authors: M Kim, K Jung, IS Kim, IS Lee, Y Ko, JE Shin, KI Park
Exp. Mol. Med., 2018-04-06;50(4):14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
Authors: N Guzzi, M Cie?la, PCT Ngoc, S Lang, S Arora, M Dimitriou, K Pimková, MNE Sommarin, R Munita, M Lubas, Y Lim, K Okuyama, S Soneji, G Karlsson, J Hansson, G Jönsson, AH Lund, M Sigvardsso, E Hellström-, AC Hsieh, C Bellodi
Cell, 2018-04-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neural Stem Cell-Conditioned Medium Ameliorated Cerebral Ischemia-Reperfusion Injury in Rats
Authors: H Yang, C Wang, H Chen, L Li, S Ma, H Wang, Y Fu, T Qu
Stem Cells Int, 2018-04-03;2018(0):4659159.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity
Authors: D Poppe, J Doerr, M Schneider, R Wilkens, JA Steinbeck, J Ladewig, A Tam, DE Paschon, PD Gregory, A Reik, CE Müller, P Koch, O Brüstle
Stem Cells Transl Med, 2018-03-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis
Authors: SM Planchon, KT Lingas, J Reese Koç, BM Hooper, B Maitra, RM Fox, PB Imrey, KM Drake, MA Aldred, HM Lazarus, JA Cohen
Mult Scler J Exp Transl Clin, 2018-03-26;4(1):2055217318765.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
iPSCs from a Hibernator Provide a Platform for Studying Cold Adaptation and Its Potential Medical Applications
Authors: J Ou, JM Ball, Y Luan, T Zhao, KJ Miyagishim, Y Xu, H Zhou, J Chen, DK Merriman, Z Xie, BS Mallon, W Li
Cell, 2018-03-22;0(0):.
Species: Squirrel
Sample Types: Whole Cells
Applications: Bioassay -
Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood
Authors: FN Vögtle, B Brändl, A Larson, M Pendziwiat, MW Friederich, SM White, A Basinger, C Kücükköse, H Muhle, JA Jähn, O Keminer, KL Helbig, CF Delto, L Myketin, D Mossmann, N Burger, N Miyake, A Burnett, A van Baalen, MA Lovell, N Matsumoto, M Walsh, HC Yu, DN Shinde, U Stephani, JLK Van Hove, FJ Müller, I Helbig
Am. J. Hum. Genet., 2018-03-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells
Authors: M Zhang, J Ngo, F Pirozzi, YP Sun, A Wynshaw-Bo
Stem Cell Res Ther, 2018-03-15;9(1):67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Subcellular localisation modulates ubiquitylation and degradation of Ascl1
Authors: S Gillotin, JD Davies, A Philpott
Sci Rep, 2018-03-15;8(1):4625.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells
Authors: R Tang, L Jing, VP Willard, CL Wu, F Guilak, J Chen, LA Setton
Stem Cell Res Ther, 2018-03-09;9(1):61.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Beta-Catenin maintains lung epithelial progenitors after lung specification
Authors: EJ Ostrin, DR Little, KN Gerner-Mau, EA Sumner, R Ríos-Corzo, E Ambrosio, SE Holt, NR Forcioli-C, H Akiyama, SM Hanash, S Kimura, SXL Huang, J Chen
Development, 2018-03-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Antisense Therapy for a Common Corneal Dystrophy Ameliorates TCF4 Repeat Expansion-Mediated Toxicity
Authors: C Zarouchlio, B Sanchez-Pi, NJ Hafford Te, P Klein, P Liskova, K Dulla, M Semo, AA Vugler, K Muthusamy, L Dudakova, HJ Levis, P Skalicka, P Hysi, ME Cheetham, SJ Tuft, P Adamson, AJ Hardcastle, AE Davidson
Am. J. Hum. Genet., 2018-03-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma
Authors: F Ihler, R Gratz, HA Wolff, BG Weiss, M Bertlich, J Kitz, G Salinas, M Rave-Fränk, M Canis
Biomed Res Int, 2018-03-06;2018(0):7929104.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A novel ex vivo Huntington's disease model for studying GABAergic neurons and cell grafts by laser microdissection
Authors: EM André, N Daviaud, L Sindji, J Cayon, R Perrot, CN Montero-Me
PLoS ONE, 2018-03-05;13(3):e0193409.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of a novel OTX2-driven stem cell program in Group 3 and Group 4 medulloblastoma
Authors: M Stromecki, N Tatari, LC Morrison, R Kaur, J Zagozewski, G Palidwor, V Ramaswamy, P Skowron, M Wölfl, T Milde, MR Del Bigio, MD Taylor, TE Werbowetsk
Mol Oncol, 2018-03-01;12(4):495-513.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Negative regulation of lens fiber cell differentiation by RTK antagonists Spry and Spred
Authors: G Zhao, CG Bailey, Y Feng, J Rasko, FJ Lovicu
Exp. Eye Res., 2018-03-01;170(0):148-159.
Species: Rat
Sample Types: Whole Tissue
Applications: Bioassay -
SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition
Authors: W Wang, D Chen, K Zhu
J. Exp. Clin. Cancer Res., 2018-02-23;37(1):37.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Functional brain-specific microvessels from iPSC-derived human brain microvascular endothelial cells: the role of matrix composition on monolayer formation
Authors: ME Katt, RM Linville, LN Mayo, ZS Xu, PC Searson
Fluids Barriers CNS, 2018-02-20;15(1):7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeted BiTE expression by an oncolytic vector augments therapeutic efficacy against solid tumors
Authors: T Speck, JP Heidbueche, R Veinalde, D Jaeger, C von Kalle, CR Ball, G Ungerechts, CE Engeland
Clin. Cancer Res., 2018-02-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors
Authors: C Laterza, N Uoshima, D Tornero, U Wilhelmsso, A Stokowska, R Ge, M Pekny, O Lindvall, Z Kokaia
PLoS ONE, 2018-02-05;13(2):e0192118.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Establishment of a three-dimensional model to study human uterine angiogenesis
Authors: CL Duran, CA Abbey, KJ Bayless
Mol. Hum. Reprod., 2018-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Topical vancomycin and its effect on survival and migration of osteoblasts, fibroblasts, and myoblasts: An in vitro study
Authors: JX Liu, D Bravo, J Buza, T Kirsch, O Kennedy, A Rokito, JD Zuckerman, MS Virk
J Orthop, 2018-01-30;15(1):53-58.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney
Authors: SD Muthukrish, S Ryzhov, M Karolak, L Oxburgh
Dis Model Mech, 2018-01-29;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Donor variability in growth kinetics of healthy hMSCs using manual processing: considerations for manufacture of cell therapies
Authors: G Detela, OW Bain, HW Kim, DJ Williams, C Mason, A Mathur, IB Wall
Biotechnol J, 2018-01-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The antigen ASB4 on cancer stem cells serves as a target for CTL immunotherapy of colorectal cancer
Authors: S Miyamoto, V Kochin, T Kanaseki, A Hongo, S Tokita, Y Kikuchi, A Takaya, Y Hirohashi, T Tsukahara, T Terui, K Ishitani, F Hata, I Takemasa, A Miyazaki, H Hiratsuka, N Sato, T Torigoe
Cancer Immunol Res, 2018-01-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells
Authors: N Dreyer-And, AS Almeida, P Jensen, M Kamand, J Okarmus, T Rosenberg, SD Friis, A Martínez S, M Blaabjerg, BW Kristensen, T Skrydstrup, JB Gramsberge, HLA Vieira, M Meyer
PLoS ONE, 2018-01-16;13(1):e0191207.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fast neurogenesis from carotid body quiescent neuroblasts accelerates adaptation to hypoxia
Authors: V Sobrino, P González-R, V Annese, J López-Barn, R Pardal
EMBO Rep., 2018-01-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction
Authors: G Zhou, H Jiang, Z Yin, Y Liu, Q Zhang, C Zhang, B Pan, J Zhou, X Zhou, H Sun, D Li, A He, Z Zhang, W Zhang, W Liu, Y Cao
EBioMedicine, 2018-01-13;28(0):287-302.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors
Authors: CJ Drummond, JA Hanna, MR Garcia, DJ Devine, AJ Heyrana, D Finkelstei, JE Rehg, ME Hatley
Cancer Cell, 2018-01-08;33(1):108-124.e5.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation
Authors: JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark
Stem Cell Res, 2018-01-04;27(0):46-56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Breast cancer stem cells in HER2-negative breast cancer cells contribute to HER2-mediated radioresistance and molecular subtype conversion: clinical implications for serum HER2 in recurrent HER2-negative breast cancer
Authors: YG Kim, YN Yoon, HS Choi, JH Kim, H Seol, JK Lee, MK Seong, IC Park, KI Kim, HA Kim, JS Kim, WC Noh
Oncotarget, 2017-12-20;9(5):5811-5822.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cografting astrocytes improves cell therapeutic outcomes in a Parkinson's disease model
Authors: JJ Song, SM Oh, OC Kwon, N Wulnansari, HS Lee, MY Chang, E Lee, W Sun, SE Lee, S Chang, H An, CJ Lee, SH Lee
J. Clin. Invest., 2017-12-11;0(0):.
Species: Mouse, Rat
Sample Types: Whole Cells
Applications: Bioassay -
Bone marrow drives central nervous system regeneration after radiation injury
Authors: J Dietrich, N Baryawno, N Nayyar, YK Valtis, B Yang, I Ly, A Besnard, N Severe, KU Gustafsson, OC Andronesi, TT Batchelor, A Sahay, DT Scadden
J. Clin. Invest., 2017-12-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Circumferential Esophageal Replacement by a Tissue-engineered Substitute Using Mesenchymal Stem Cells: An Experimental Study in Mini Pigs
Authors: J Catry, M Luong-Nguy, L Arakelian, T Poghosyan, P Bruneval, T Domet, L Michaud, R Sfeir, F Gottrand, J Larghero, V Vanneaux, P Cattan
Cell Transplant, 2017-12-01;26(12):1831-1839.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay -
Retinoic Acid-Signaling Regulates the Proliferative and Neurogenic Capacity of M�ller Glia-Derived Progenitor Cells in the Avian Retina
Authors: L Todd, L Suarez, C Quinn, AJ Fischer
Stem Cells, 2017-11-27;0(0):.
Species: Chicken
Sample Types: In Vivo
Applications: In Vivo -
Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
Authors: A Taguchi, R Nishinakam
Cell Stem Cell, 2017-11-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Differentiation, Differentiation -
Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells
Authors: T Johansen, C Krabbe, SI Schmidt, AM Serrano, M Meyer
Stem Cells Int, 2017-10-22;2017(0):9605432.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas
Authors: HM Lee, JW Joh, SR Seo, WT Kim, MK Kim, HS Choi, SY Kim, YJ Jang, DH Sinn, GS Choi, JM Kim, CHD Kwon, HJ Chang, DS Kim, CJ Ryu
Sci Rep, 2017-10-16;7(1):13201.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA
Authors: A Wahba, MC Ryan, UT Shankavara, K Camphausen, PJ Tofilon
Oncotarget, 2017-10-09;9(1):691-705.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Real-time assessment of corneal endothelial cell damage following graft preparation and donor insertion for DMEK
Authors: M Bhogal, CN Lwin, XY Seah, E Murugan, K Adnan, SJ Lin, G Peh, JS Mehta
PLoS ONE, 2017-10-04;12(10):e0184824.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways
Authors: F Wang, AY Wang, C Chesnelong, Y Yang, A Nabbi, S Thalappill, V Alekseev, K Riabowol
Oncogene, 2017-09-18;37(3):286-301.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma
Authors: VT Cheriyan, HO Alsaab, S Sekhar, C Stieber, P Kesharwani, S Sau, M Muthu, LA Polin, E Levi, AK Iyer, AK Rishi
Oncotarget, 2017-09-05;8(62):104928-104945.
Applications: Bioassay -
In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
Sci Rep, 2017-08-17;7(1):8491.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
Cell Stem Cell, 2017-08-03;21(2):179-194.e4.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
TMPRSS4 promotes cancer stem cell traits by regulating CLDN1 in hepatocellular carcinoma
Authors: S Mahati, D Bolati, Y Yang, R Mao, H Zhang, Y Bao
Biochem. Biophys. Res. Commun., 2017-06-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes
Authors: J Kuusela, K Larsson, D Shah, C Prajapati, K Aalto-Setä
Biol Open, 2017-06-15;6(6):777-784.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction
Authors: A De Pauw, E Andre, B Sekkali, C Bouzin, H Esfahani, N Barbier, A Loriot, C De Smet, L Vanhoutte, S Moniotte, B Gerber, V di Mauro, D Catalucci, O Feron, D Hilfiker-K, JL Balligand
JCI Insight, 2017-06-15;2(12):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance
Authors: RO Pereira, SM Tadinada, FM Zasadny, KJ Oliveira, KMP Pires, A Olvera, J Jeffers, R Souvenir, R Mcglauflin, A Seei, T Funari, H Sesaki, MJ Potthoff, CM Adams, EJ Anderson, ED Abel
EMBO J., 2017-06-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeting the Wnt pathway and cancer stem cells with anti-progastrin humanized antibodies: a major breakthrough for K-RAS mutated colorectal cancer treatment
Authors: A Prieur, M Cappellini, G Habif, MP Lefranc, T Mazard, E Morency, JM Pascussi, M Flaceliere, N Cahuzac, B Vire, B Dubuc, A Durochat, P Liaud, J Ollier, C Pfeiffer, S Poupeau, V Saywell, C Planque, E Assenat, F Bibeau, JF Bourgaux, P Pujol, A Sézeur, M Ychou, D Joubert
Clin. Cancer Res., 2017-06-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells
Authors: KG Wong, SD Ryan, K Ramnarine, SA Rosen, SE Mann, A Kulick, E De Stanchi, FJ Müller, TJ Kacmarczyk, C Zhang, D Betel, MJ Tomishima
Stem Cell Reports, 2017-06-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Ureteral reconstruction with reinforced collagen scaffolds in a porcine model
Authors: Wout Feitz
J Tissue Eng Regen Med, 2017-06-07;0(0):.
Applications: Bioassay -
Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
Nat Commun, 2017-05-25;8(0):15380.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate
Authors: JR Chao, DA Lamba, TR Klesert, A Torre, A Hoshino, RJ Taylor, A Jayabalu, AL Engel, TH Khuu, RK Wang, M Neitz, J Neitz, TA Reh
Transl Vis Sci Technol, 2017-05-16;6(3):4.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival
Authors: Y Pan, LJ Smithson, Y Ma, D Hambardzum, DH Gutmann
Oncotarget, 2017-05-16;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
Authors: JK Hu, W Du, SJ Shelton, MC Oldham, CM DiPersio, OD Klein
Cell Stem Cell, 2017-04-27;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells
Authors: DJ Tischfield, J Kim, SA Anderson
Stem Cell Reports, 2017-04-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia
Authors: R Allison, JR Edgar, G Pearson, T Rizo, T Newton, S Günther, F Berner, J Hague, JW Connell, J Winkler, J Lippincott, C Beetz, B Winner, E Reid
J. Cell Biol., 2017-04-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci
Authors: EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, J Arbelaez, M Hernandez, N Kuperwasse, W Li, Z Lian, Y Liu, W Lv, SL Lytle-Gabb, DH Marchadier, P Rogov, J Shi, KJ Slovik, IM Stylianou, L Wang, R Yan, X Zhang, S Kathiresan, SA Duncan, TS Mikkelsen, EE Morrisey, DJ Rader, CD Brown, K Musunuru
Cell Stem Cell, 2017-04-06;20(4):558-570.e10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Gelatin device for the delivery of growth factors involved in endochondral ossification
Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
PLoS ONE, 2017-04-05;12(4):e0175095.
Species: Chicken, Human
Sample Types: Whole Cells, Whole Embryo
Applications: Bioassay -
Combining Injectable Plasma Scaffold with Mesenchymal Stem/Stromal Cells for Repairing Infarct Cavity after Ischemic Stroke
Authors: H Zhang, F Sun, J Wang, L Xie, C Yang, M Pan, B Shao, GY Yang, SH Yang, Q ZhuGe, K Jin
Aging Dis, 2017-04-01;8(2):203-214.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
Authors: KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton
Cell Stem Cell, 2017-03-30;0(0):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB
Authors: NA Guadagno, C Moriconi, V Licursi, E D'Acunto, PS Nisi, N Carucci, A De Jaco, E Cacci, R Negri, G Lupo, E Miranda
Neurobiol. Dis., 2017-03-28;103(0):32-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity
Authors: DC Thomas, S Clare, JM Sowerby, M Pardo, JK Juss, DA Goulding, L van der We, D Storistean, A Prakash, M Espéli, S Flint, JC Lee, K Hoenderdos, L Kane, K Harcourt, S Mukhopadhy, Y Umrania, R Antrobus, JA Nathan, DJ Adams, A Bateman, JS Choudhary, PA Lyons, AM Condliffe, ER Chilvers, G Dougan, KG Smith
J. Exp. Med, 2017-03-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expression of Pluripotency Markers in Non-pluripotent Human Neural Stem and Progenitor Cells
Authors: PH Vincent, E Benedikz, P Uhlen, O Hovatta, E Sundström
Stem Cells Dev., 2017-03-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
Nat Protoc, 2017-03-23;12(4):814-827.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Biomimetic Calcium Phosphate/Polyelectrolyte Multilayer Coatings for Sequential Delivery of Multiple Biological Factors
Authors: E Jacobs
J Biomed Mater Res A, 2017-03-20;0(0):.
-
A cell-autonomous positive-signaling circuit associated with the PDGF-NO-ID4-regulatory axis in glioblastoma cells
Authors: K Eun, HM Jeon, SO Kim, SH Choi, SY Lee, X Jin, SC Kim, H Kim
Biochem. Biophys. Res. Commun, 2017-03-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeting BMI1(+) Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma
Authors: D Chen, M Wu, Y Li, I Chang, Q Yuan, M Ekimyan-Sa, P Deng, B Yu, Y Yu, J Dong, JM Szymanski, S Ramadoss, J Li, CY Wang
Cell Stem Cell, 2017-03-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform
Authors: I Rudnik-Jan, S Colen, J Berard, S Plomp, I Que, M van Rijen, N Woike, A Egas, G van Osch, E van Maarse, K Messier, A Chan, J Thies, L Creemers
J Control Release, 2017-03-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fast transdifferentiation of human Wharton's jelly mesenchymal stem cells into neurospheres and nerve-like cells
Authors: AR Bonilla-Po, C Velez-Pard, M Jimenez-De
J. Neurosci. Methods, 2017-03-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3
Authors: H He, AE Kuriyan, CW Su, M Mahabole, Y Zhang, YT Zhu, HW Flynn, JM Parel, SC Tseng
Sci Rep, 2017-03-02;7(0):43736.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy
Authors: R Horibe, Y Hirohashi, T Asano, T Mariya, T Suzuki, A Takaya, H Saijo, Y Shionoya, T Kubo, M Nakatsugaw, T Kanaseki, T Tsukahara, K Watanabe, E Atsuyama, S Toji, H Hirano, T Hasegawa, H Takahashi, N Sato, T Torigoe
PLoS ONE, 2017-03-01;12(3):e0171460.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells
Authors: L Wang, Y Hirohashi, T Ogawa, M Shen, R Takeda, A Murai, E Yamamoto, T Kubo, M Nakatsugaw, T Kanaseki, T Tsukahara, T Nishidate, K Okita, G Kutomi, N Sato, I Takemasa, T Torigoe
Biochem. Biophys. Res. Commun, 2017-02-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Nutritional modulation of mouse and human liver bud growth through a branched-amino acid metabolism
Authors: H Koike, RR Zhang, Y Ueno, K Sekine, YW Zheng, T Takebe, H Taniguchi
Development, 2017-02-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering
Authors: F Chen, Y Ni, B Liu, T Zhou, C Yu, Y Su, X Zhu, X Yu, Y Zhou
Carbohydr Polym, 2017-02-20;166(0):31-44.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay -
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
Authors: AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou
Cell Stem Cell, 2017-02-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived From Human Induced Pluripotent Stem Cells After Intracerebral Transplantation
Authors: JC Niclis, C Turner, J Durnall, S McDougal, JA Kauhausen, B Leaw, M Dottori, CL Parish, LH Thompson
Stem Cells Transl Med, 2017-02-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex
Authors: E Ercan, JM Han, A Di Nardo, K Winden, MJ Han, L Hoyo, A Saffari, A Leask, DH Geschwind, M Sahin
J. Exp. Med, 2017-02-09;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Development of a human cardiac organoid injury model reveals innate regenerative potential
Authors: HK Voges, RJ Mills, DA Elliott, RG Parton, ER Porrello, JE Hudson
Development, 2017-02-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
Authors: JS Saini, B Corneo, JD Miller, TR Kiehl, Q Wang, NC Boles, TA Blenkinsop, JH Stern, S Temple
Cell Stem Cell, 2017-01-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Skeletal muscle atrophy is induced by Fbxw7? via atrogene upregulation
Authors: Kyungshin Shin
Cell Biol. Int, 2017-01-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats
Authors: Xiu Li Ju
Yonsei Med. J., 2017-01-01;58(1):206-216.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay -
Increased susceptibility to a? toxicity in neuronal cultures derived from familial Azheimer's disease (PSEN1-A246E) induced pluripotent stem cells
Authors: Enrique Armijo
Neurosci. Lett, 2016-12-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
Authors: Ivan Carcamo-Or
Cell Stem Cell, 2016-12-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition
Authors: Young Dong Yoo
EMBO Rep, 2016-12-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination
Authors: Xiaoguang Fang
J. Exp. Med, 2016-12-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Derivation of chicken induced pluripotent stem cells tolerant to Newcastle disease virus-induced lysis through multiple rounds of infection
Authors: Leonardo Susta
Virol. J, 2016-12-05;13(1):205.
Species: Chicken
Sample Types: Whole Cells
Applications: Bioassay -
Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta
Authors: Amber N Stratman
Development, 2016-12-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Intra-laboratory validated human cell-based in vitro vasculogenesis/angiogenesis test with serum-free medium
Authors: T Toimela
Reprod. Toxicol, 2016-11-30;0(0):.
Species: Human
Sample Types:
-
iPS-derived neural progenitor cells from PPMS patients reveal defect in myelin injury response
Authors: Stephen J Crocker
Exp. Neurol., 2016-11-16;288(0):114-121.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial�cells
Nat. Cell Biol., 2016-11-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
Nat. Med., 2016-11-14;22(12):1421-1427.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination with Cell Polarization During Ameloblast Differentiation
J Bone Miner Res, 2016-10-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages
Authors: L Zhu, A Gomez-Dura, G Saretzki, S Jin, K Tilgner, D Melguizo-S, G Anyfantis, J Al-Aama, L Vallier, P Chinnery, M Lako, L Armstrong
J. Cell Biol., 2016-10-17;215(2):187-202.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation
Sci Rep, 2016-09-16;6(0):33407.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain.
Authors: Deverman B, Pravdo P, Simpson B, Kumar S, Chan K, Banerjee A, Wu W, Yang B, Huber N, Pasca S, Gradinaru V
Nat Biotechnol, 2016-02-01;34(2):204-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation
Authors: Robert Thomas
Biotechnol. Prog., 2015-11-28;32(1):215-23.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The schizophrenia risk gene product miR-137 alters presynaptic plasticity.
Authors: Siegert S, Seo J, Kwon E, Rudenko A, Cho S, Wang W, Flood Z, Martorell A, Ericsson M, Mungenast A, Tsai L
Nat Neurosci, 2015-05-25;18(7):1008-16.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Prolonged and tunable residence time using reversible covalent kinase inhibitors.
Authors: Bradshaw J, McFarland J, Paavilainen V, Bisconte A, Tam D, Phan V, Romanov S, Finkle D, Shu J, Patel V, Ton T, Li X, Loughhead D, Nunn P, Karr D, Gerritsen M, Funk J, Owens T, Verner E, Brameld K, Hill R, Goldstein D, Taunton J
Nat Chem Biol, 2015-05-25;11(7):525-31.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cellular Responses Modulated by FGF-2 Adsorbed on Albumin/Heparin Layer-by-Layer Assemblies.
Authors: Kumorek M, Kubies D, Filova E, Houska M, Kasoju N, Mazl Chanova E, Matejka R, Kryslova M, Bacakova L, Rypacek F
PLoS ONE, 2015-05-06;10(5):e0125484.
Species: Bovine, Human
Sample Types: Protein, Whole Cells
Applications: Bioassay -
Improved neurological outcome by intramuscular injection of human amniotic fluid derived stem cells in a muscle denervation model.
Authors: Chen C, Cheng F, Su H, Sheu M, Lu Z, Chiang C, Yang D, Sheehan J, Pan H
PLoS ONE, 2015-05-06;10(5):e0124624.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Enhanced SMAD1 Signaling Contributes to Impairments of Early Development in CFC-iPSCs.
Authors: Han K, Kim S, Kim D, Choi J, Im I, Hwang K, Kim C, Lee B, Yoo H, Han Y
Stem Cells, 2015-05-01;33(5):1447-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
Authors: Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings V, Boileau M, Bellamy D, Bastin D, de Souza C, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne S, Paramanthan P, Chatterjee A, Strieter R, Burdick M, Addison C, Stojdl D, Atkins H, Auer R, Diallo J, Lichty B, Bell J
Nat Med, 2015-04-20;21(5):530-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1.
Authors: Majumder A, Syed K, Joseph S, Scambler P, Dutta D
J Biol Chem, 2015-04-06;290(21):13053-63.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.
Authors: Iyer D, Gambardella L, Bernard W, Serrano F, Mascetti V, Pedersen R, Talasila A, Sinha S
Development, 2015-03-26;142(8):1528-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
Authors: Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G
Nat Commun, 2015-03-26;6(0):6576.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
In vitro generation of human pluripotent stem cell derived lung organoids.
Authors: Dye, Briana R, Hill, David R, Ferguson, Michael, Tsai, Yu-Hwai, Nagy, Melinda, Dyal, Rachel, Wells, James M, Mayhew, Christop, Nattiv, Roy, Klein, Ophir D, White, Eric S, Deutsch, Gail H, Spence, Jason R
Elife, 2015-03-24;4(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors.
Authors: Edri, Reuven, Yaffe, Yakey, Ziller, Michael, Mutukula, Naresh, Volkman, Rotem, David, Eyal, Jacob-Hirsch, Jasmine, Malcov, Hagar, Levy, Carmit, Rechavi, Gideon, Gat-Viks, Irit, Meissner, Alexande, Elkabetz, Yechiel
Nat Commun, 2015-03-23;6(0):6500.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Resveratrol ameliorates the maturation process of beta-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
Authors: Pezzolla D, Lopez-Beas J, Lachaud C, Dominguez-Rodriguez A, Smani T, Hmadcha A, Soria B
PLoS ONE, 2015-03-16;10(3):e0119904.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
V-myc immortalizes human neural stem cells in the absence of pluripotency-associated traits.
Authors: Pino-Barrio M, Garcia-Garcia E, Menendez P, Martinez-Serrano A
PLoS ONE, 2015-03-12;10(3):e0118499.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta.
Authors: Tabata T, Petitt M, Zydek M, Fang-Hoover J, Larocque N, Tsuge M, Gormley M, Kauvar L, Pereira L
J Virol, 2015-03-04;89(9):5134-47.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mitochondrial control by DRP1 in brain tumor initiating cells.
Authors: Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, Dombrowski S, Huang Z, Fang X, Shi Y, Ferguson A, Kashatus D, Bao S, Rich J
Nat Neurosci, 2015-03-02;18(4):501-10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Temporal and embryonic lineage-dependent regulation of human vascular SMC development by NOTCH3.
Authors: Granata A, Bernard W, Zhao N, McCafferty J, Lilly B, Sinha S
Stem Cells Dev, 2015-02-25;24(7):846-56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
mTOR inhibition improves fibroblast growth factor receptor targeting in hepatocellular carcinoma.
Authors: Scheller, T, Hellerbrand, C, Moser, C, Schmidt, K, Kroemer, A, Brunner, S M, Schlitt, H J, Geissler, E K, Lang, S A
Br J Cancer, 2015-02-17;112(5):841-50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
Nat Protoc, 2015-02-05;10(3):413-25.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Nerve growth factor and proNGF simultaneously promote symmetric self-renewal, quiescence, and epithelial to mesenchymal transition to enlarge the breast cancer stem cell compartment.
Authors: Tomellini E, Touil Y, Lagadec C, Julien S, Ostyn P, Ziental-Gelus N, Meignan S, Lengrand J, Adriaenssens E, Polakowska R, Le Bourhis X
Stem Cells, 2015-02-01;33(2):342-53.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors.
Authors: All A, Gharibani P, Gupta S, Bazley F, Pashai N, Chou B, Shah S, Resar L, Cheng L, Gearhart J, Kerr C
PLoS ONE, 2015-01-30;10(1):e0116933.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer.
Authors: Wu, Bo, Cao, Xiaoming, Liang, Xuezhi, Zhang, Xuhui, Zhang, Wei, Sun, Guang, Wang, Dongwen
PLoS ONE, 2015-01-28;10(1):e0117510.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The evidence of glioblastoma heterogeneity.
Authors: Soeda, Akio, Hara, Akira, Kunisada, Takahiro, Yoshimura, Shin-ich, Iwama, Toru, Park, Deric M
Sci Rep, 2015-01-27;5(0):7979.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia.
Authors: Chen X, Wales P, Quinti L, Zuo F, Moniot S, Herisson F, Rauf N, Wang H, Silverman R, Ayata C, Maxwell M, Steegborn C, Schwarzschild M, Outeiro T, Kazantsev A
PLoS ONE, 2015-01-21;10(1):e0116919.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
PLoS ONE, 2014-12-26;9(12):e116114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Selective calcium sensitivity in immature glioma cancer stem cells.
Authors: Wee S, Niklasson M, Marinescu V, Segerman A, Schmidt L, Hermansson A, Dirks P, Forsberg-Nilsson K, Westermark B, Uhrbom L, Linnarsson S, Nelander S, Andang M
PLoS ONE, 2014-12-22;9(12):e115698.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Endophilin marks and controls a clathrin-independent endocytic pathway.
Authors: Boucrot E, Ferreira A, Almeida-Souza L, Debard S, Vallis Y, Howard G, Bertot L, Sauvonnet N, McMahon H
Nature, 2014-12-17;517(7535):460-5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Transcriptional profiling of adult neural stem-like cells from the human brain.
Authors: Sandberg C, Vik-Mo E, Behnan J, Helseth E, Langmoen I
PLoS ONE, 2014-12-16;9(12):e114739.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Ecto-5'-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature.
Authors: Yegutkin G, Auvinen K, Rantakari P, Hollmen M, Karikoski M, Grenman R, Elima K, Jalkanen S, Salmi M
Eur J Immunol, 2014-12-15;45(2):562-73.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.
Authors: Shen K, Luk S, Hicks D, Elman J, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush M, Toner M, Sgroi D, Parekkadan B
Nat Commun, 2014-12-09;5(0):5662.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.
Authors: Flierl A, Oliveira L, Falomir-Lockhart L, Mak S, Hesley J, Soldner F, Arndt-Jovin D, Jaenisch R, Langston J, Jovin T, Schule B
PLoS ONE, 2014-11-12;9(11):e112413.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Tissue-engineered vascular grafts created from human induced pluripotent stem cells.
Authors: Sundaram S, One J, Siewert J, Teodosescu S, Zhao L, Dimitrievska S, Qian H, Huang A, Niklason L
Stem Cells Transl Med, 2014-11-05;3(12):1535-43.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Histone hyperacetylation up-regulates protein kinase Cdelta in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease.
Authors: Jin H, Kanthasamy A, Harischandra D, Kondru N, Ghosh A, Panicker N, Anantharam V, Rana A, Kanthasamy A
J Biol Chem, 2014-10-23;289(50):34743-67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation.
Authors: Hirata, Naoya, Yamada, Shigeru, Shoda, Takuji, Kurihara, Masaaki, Sekino, Yuko, Kanda, Yasunari
Nat Commun, 2014-09-25;5(0):4806.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.
Authors: Falcon B, Swearingen M, Gough W, Lee L, Foreman R, Uhlik M, Hanson J, Lee J, McClure D, Chintharlapalli S
PLoS ONE, 2014-09-11;9(9):e106901.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells.
Authors: Lee, Rimi, Kim, Il-Sun, Han, Nalae, Yun, Seokhwan, Park, Kook In, Yoo, Kyung-Hw
Sci Rep, 2014-09-10;4(0):6319.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expansion of murine periosteal progenitor cells with fibroblast growth factor 2 reveals an intrinsic endochondral ossification program mediated by bone morphogenetic protein 2.
Authors: van Gastel N, Stegen S, Stockmans I, Moermans K, Schrooten J, Graf D, Luyten F, Carmeliet G
Stem Cells, 2014-09-01;32(9):2407-18.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Cis-acting DNA sequence at a replication origin promotes repeat expansion to fragile X full mutation.
Authors: Gerhardt J, Zaninovic N, Zhan Q, Madireddy A, Nolin S, Ersalesi N, Yan Z, Rosenwaks Z, Schildkraut C
J Cell Biol, 2014-09-01;206(5):599-607.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Long non-coding RNAs as surrogate indicators for chemical stress responses in human-induced pluripotent stem cells.
Authors: Tani, Hidenori, Onuma, Yasuko, Ito, Yuzuru, Torimura, Masaki
PLoS ONE, 2014-08-29;9(8):e106282.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
Authors: Mathur, Anjili, Ware, Christop, Davis, Lenora, Gazdar, Adi, Pan, Bo-Sheng, Lutterbach, Bart
PLoS ONE, 2014-06-26;9(6):e98515.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
High efficient differentiation of functional hepatocytes from porcine induced pluripotent stem cells.
Authors: Ao, Ying, Mich-Basso, Jocelyn, Lin, Bo, Yang, Lei
PLoS ONE, 2014-06-20;9(6):e100417.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay -
CoCl2, a mimic of hypoxia, induces formation of polyploid giant cells with stem characteristics in colon cancer.
Authors: Lopez-Sanchez L, Jimenez C, Valverde A, Hernandez V, Penarando J, Martinez A, Lopez-Pedrera C, Munoz-Castaneda J, De la Haba-Rodriguez J, Aranda E, Rodriguez-Ariza A
PLoS ONE, 2014-06-16;9(6):e99143.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Chondrogenesis of infrapatellar fat pad derived adipose stem cells in 3D printed chitosan scaffold.
Authors: Ye K, Felimban R, Traianedes K, Moulton S, Wallace G, Chung J, Quigley A, Choong P, Myers D
PLoS ONE, 2014-06-11;9(6):e99410.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1.
Authors: Zhao C, Pavicic P, Datta S, Sun D, Novotny M, Hamilton T
J Immunol, 2014-06-11;193(2):879-88.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs.
Authors: Park, Chul-Yon, Kim, Jungeun, Kweon, Jiyeon, Son, Jeong Sa, Lee, Jae Souk, Yoo, Jeong-Eu, Cho, Sung-Rae, Kim, Jong-Hoo, Kim, Jin-Soo, Kim, Dong-Woo
Proc Natl Acad Sci U S A, 2014-06-09;111(25):9253-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Genetic background drives transcriptional variation in human induced pluripotent stem cells.
Authors: Rouhani, Foad, Kumasaka, Natsuhik, de Brito, Miguel C, Bradley, Allan, Vallier, Ludovic, Gaffney, Daniel
PLoS Genet, 2014-06-05;10(6):e1004432.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10.
Authors: Kanehira M, Kikuchi T, Santoso A, Tode N, Hirano T, Ohkouchi S, Tamada T, Sugiura H, Harigae H, Ichinose M
Mol Cell Biol, 2014-05-27;34(15):2848-56.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Polycomb group protein expression during differentiation of human embryonic stem cells into pancreatic lineage in vitro.
Authors: Pethe, Prasad, Nagvenkar, Punam, Bhartiya, Deepa
BMC Cell Biol, 2014-05-24;15(0):18.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mesenchymal stromal cells support the viability and differentiation of follicular lymphoma-infiltrating follicular helper T-cells.
Authors: Brady M, Hilchey S, Hyrien O, Spence S, Bernstein S
PLoS ONE, 2014-05-16;9(5):e97597.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging.
Authors: Stein L, Imai S
EMBO J, 2014-05-08;33(12):1321-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells.
Authors: Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S
Stem Cells, 2014-05-01;32(5):1337-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.
Authors: Yan K, Wu Q, Yan D, Lee C, Rahim N, Tritschler I, DeVecchio J, Kalady M, Hjelmeland A, Rich J
Genes Dev, 2014-05-01;28(10):1085-100.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of bladder urothelium from human pluripotent stem cells under chemically defined serum- and feeder-free system.
Authors: Kang, Minyong, Kim, Hyeon Ho, Han, Yong-Mah
Int J Mol Sci, 2014-04-25;15(5):7139-57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling.
Authors: Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, Moser C, Shaleh H, Thornburgh S, Walters I, Roberts L
PLoS ONE, 2014-04-07;9(4):e92273.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study.
Authors: Zheng G, Huang L, Tong H, Shu Q, Hu Y, Ge M, Deng K, Zhang L, Zou B, Cheng B, Xu J
Respir Res, 2014-04-04;15(0):39.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Inner ear hair cell-like cells from human embryonic stem cells.
Authors: Ronaghi, Mohammad, Nasr, Marjan, Ealy, Megan, Durruthy-Durruthy, Robert, Waldhaus, Joerg, Diaz, Giovanni, Joubert, Lydia-Ma, Oshima, Kazuo, Heller, Stefan
Stem Cells Dev, 2014-03-10;23(11):1275-84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The multifunctional growth factor midkine promotes proliferation and migration in pancreatic cancer.
Authors: Rawnaq T, Dietrich L, Wolters-Eisfeld G, Uzunoglu F, Vashist Y, Bachmann K, Simon R, Izbicki J, Bockhorn M, Gungor C
Mol Cancer Res, 2014-02-24;12(5):670-80.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Angiogenic sprouting is regulated by endothelial cell expression of Slug.
Authors: Welch-Reardon K, Ehsan S, Wang K, Wu N, Newman A, Romero-Lopez M, Fong A, George S, Edwards R, Hughes C
J Cell Sci, 2014-02-19;127(0):2017-28.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.
Authors: Takebe, Takanori, Zhang, Ran-Ran, Koike, Hiroyuki, Kimura, Masaki, Yoshizawa, Emi, Enomura, Masahiro, Koike, Naoto, Sekine, Keisuke, Taniguchi, Hideki
Nat Protoc, 2014-01-23;9(2):396-409.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury.
Authors: Gericota B, Anderson J, Mitchell G, Borjesson D, Sturges B, Nolta J, Sieber-Blum M
Stem Cells Transl Med, 2014-01-17;3(3):334-45.
Species: Canine
Sample Types: Whole Tissue
Applications: Bioassay -
Hypoxic conditioned medium from human amniotic fluid-derived mesenchymal stem cells accelerates skin wound healing through TGF-beta/SMAD2 and PI3K/Akt pathways.
Authors: Jun E, Zhang Q, Yoon B, Moon J, Lee G, Park G, Kang P, Lee J, Kim A, You S
Int J Mol Sci, 2014-01-06;15(1):605-28.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Autophagy modulates SNCA/alpha-synuclein release, thereby generating a hostile microenvironment.
Authors: Poehler A, Xiang W, Spitzer P, May V, Meixner H, Rockenstein E, Chutna O, Outeiro T, Winkler J, Masliah E, Klucken J
Autophagy, 2014-01-01;10(12):2171-92.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment.
Authors: Rodin S, Antonsson L, Niaudet C, Simonson O, Salmela E, Hansson E, Domogatskaya A, Xiao Z, Damdimopoulou P, Sheikhi M, Inzunza J, Nilsson A, Baker D, Kuiper R, Sun Y, Blennow E, Nordenskjold M, Grinnemo K, Kere J, Betsholtz C, Hovatta O, Tryggvason K
Nat Commun, 2014-01-01;5(0):3195.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosis.
Authors: Roach K, Duffy S, Coward W, Feghali-Bostwick C, Wulff H, Bradding P
PLoS ONE, 2013-12-31;8(12):e85244.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
Authors: Smith A, Bowers S, Stratman A, Davis G
PLoS ONE, 2013-12-31;8(12):e85147.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
Authors: Adini, Irit, Ghosh, Kaustabh, Adini, Avner, Chi, Zai-Long, Yoshimura, Takeru, Benny, Ofra, Connor, Kip M, Rogers, Michael, Bazinet, Lauren, Birsner, Amy E, Bielenberg, Diane R, D'Amato, Robert J
J Clin Invest, 2013-12-20;124(1):425-36.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
Authors: Taguchi A, Kaku Y, Ohmori T, Sharmin S, Ogawa M, Sasaki H, Nishinakamura R
Cell Stem Cell, 2013-12-12;14(1):53-67.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.
Authors: Lotti, Fiorenza, Jarrar, Awad M, Pai, Rish K, Hitomi, Masahiro, Lathia, Justin, Mace, Adam, Gantt, Gerald A, Sukhdeo, Kumar, DeVecchio, Jennifer, Vasanji, Amit, Leahy, Patrick, Hjelmeland, Anita B, Kalady, Matthew, Rich, Jeremy N
J Exp Med, 2013-12-09;210(13):2851-72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa.
Authors: Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J
J Invest Dermatol, 2013-12-06;134(5):1246-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Adult human nasal mesenchymal-like stem cells restore cochlear spiral ganglion neurons after experimental lesion.
Authors: Bas E, Van De Water T, Lumbreras V, Rajguru S, Goss G, Hare J, Goldstein B
Stem Cells Dev, 2013-12-04;23(5):502-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells.
Authors: Lee J, Sugiyama T, Liu Y, Wang J, Gu X, Lei J, Markmann J, Miyazaki S, Miyazaki J, Szot G, Bottino R, Kim S
Elife, 2013-11-19;2(0):e00940.
-
Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model.
Authors: Chen Y, Huang W, Chang S, Chang K, Kao S, Lo J, Su P
Oncol Rep, 2013-10-01;30(6):2829-37.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer.
Authors: Palla, A R, Piazzolla, D, Abad, M, Li, H, Dominguez, O, Schonthaler, H B, Wagner, E F, Serrano, M
Oncogene, 2013-06-10;33(19):2513-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
alpha-Synuclein oligomers impair neuronal microtubule-kinesin interplay.
Authors: Prots I, Veber V, Brey S, Campioni S, Buder K, Riek R, Bohm K, Winner B
J Biol Chem, 2013-06-06;288(30):21742-54.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins.
Authors: Frohlich C, Klitgaard M, Noer J, Kotzsch A, Nehammer C, Kronqvist P, Berthelsen J, Blobel C, Kveiborg M, Albrechtsen R, Wewer U
Biochem J, 2013-05-15;452(1):97-109.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons.
Authors: Hong, Weimin C, Amara, Susan G
FASEB J, 2013-04-23;27(8):2995-3007.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
P38/NF-kappaB/snail pathway is involved in caffeic acid-induced inhibition of cancer stem cells-like properties and migratory capacity in malignant human keratinocyte.
Authors: Yang Y, Li Y, Wang K, Wang Y, Yin W, Li L
PLoS ONE, 2013-03-13;8(3):e58915.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Vaccination for invasive canine meningioma induces in situ production of antibodies capable of antibody-dependent cell-mediated cytotoxicity.
Authors: Andersen B, Pluhar G, Seiler C, Goulart M, SantaCruz K, Schutten M, Meints J, O'Sullivan M, Bentley R, Packer R, Thomovsky S, Chen A, Faissler D, Chen W, Hunt M, Olin M, Ohlfest J
Cancer Res, 2013-03-07;73(10):2987-97.
Species: Canine
Sample Types: Whole Cells
Applications: Bioassay -
BMP and TGF-beta pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells.
Authors: Cai J, Schleidt S, Pelta-Heller J, Hutchings D, Cannarsa G, Iacovitti L
Dev Biol, 2013-01-23;376(1):62-73.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Enrichment and characterization of human dermal stem/progenitor cells by intracellular granularity.
Authors: Shim, Joong Hy, Lee, Tae Ryon, Shin, Dong Woo
Stem Cells Dev, 2013-01-22;22(8):1264-74.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Distinct effects of ligand-induced PDGFRalpha and PDGFRbeta signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.
Authors: Ehnman M, Missiaglia E, Folestad E, Selfe J, Strell C, Thway K, Brodin B, Pietras K, Shipley J, Ostman A, Eriksson U
Cancer Res, 2013-01-21;73(7):2139-49.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Production of hepatocyte-like cells from human pluripotent stem cells.
Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
Nat Protoc, 2013-01-01;8(2):430-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation.
Authors: Tucker B, Anfinson K, Mullins R, Stone E, Young M
Stem Cells Transl Med, 2012-12-27;2(1):16-24.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Non-canonical TAF complexes regulate active promoters in human embryonic stem cells.
Authors: Maston G, Zhu L, Chamberlain L, Lin L, Fang M, Green M
Elife, 2012-11-13;1(0):e00068.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.
Authors: Segarra, Marta, Ohnuki, Hidetaka, Maric, Dragan, Salvucci, Ombretta, Hou, Xu, Kumar, Anil, Li, Xuri, Tosato, Giovanna
Blood, 2012-09-24;120(19):4104-15.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Endothelial heparan sulfate 6-o-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor.
Authors: Ferreras, Cristina, Rushton, Graham, Cole, Claire L, Babur, Muhammad, Telfer, Brian A, van Kuppevelt, Toin H, Gardiner, John M, Williams, Kaye J, Jayson, Gordon C, Avizienyte, Egle
J Biol Chem, 2012-08-27;287(43):36132-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c.
Authors: Di Maggio N, Mehrkens A, Papadimitropoulos A, Schaeren S, Heberer M, Banfi A, Martin I
Stem Cells, 2012-07-01;30(7):1455-64.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
PLoS ONE, 2012-04-18;7(4):e34965.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
Stem Cells Dev, 2012-02-21;21(12):2312-21.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.
Authors: Cheung C, Bernardo AS, Trotter MW
Nat. Biotechnol., 2012-01-15;30(2):165-73.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Specification of transplantable astroglial subtypes from human pluripotent stem cells.
Authors: Krencik R, Weick JP, Liu Y, Zhang ZJ, Zhang SC
Nat. Biotechnol., 2011-05-22;29(6):528-34.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres.
Authors: Walter D, Satheesha S, Albrecht P, Bornhauser BC, D'Alessandro V, Oesch SM, Rehrauer H, Leuschner I, Koscielniak E, Gengler C, Moch H, Bernasconi M, Niggli FK, Schafer BW
PLoS ONE, 2011-05-13;6(5):e19506.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Differentiation potential of human postnatal mesenchymal stem cells, mesoangioblasts, and multipotent adult progenitor cells reflected in their transcriptome and partially influenced by the culture conditions.
Authors: Roobrouck VD, Clavel C, Jacobs SA, Ulloa-Montoya F, Crippa S, Sohni A, Roberts SJ, Luyten FP, Van Gool SW, Sampaolesi M, Delforge M, Luttun A, Verfaillie CM
Stem Cells, 2011-05-01;29(5):871-82.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay -
Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation.
Authors: Pirotte S, Lamour V, Lambert V, Alvarez Gonzalez ML, Ormenese S, Noel A, Mottet D, Castronovo V, Bellahcene A
Blood, 2010-12-29;117(8):2515-26.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Endogenous expression of matriptase in neural progenitor cells promotes cell migration and neuron differentiation.
Authors: Fang JD, Chou HC, Tung HH
J. Biol. Chem., 2010-12-13;286(7):5667-79.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition.
Authors: Yang MH, Hsu DS, Wang HW
Nat. Cell Biol., 2010-09-05;12(10):982-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
PLoS ONE, 2010-08-11;5(8):e12101.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity.
Authors: Jones JL, Anderson JM, Phuah CL, Fox EJ, Selmaj K, Margolin D, Lake SL, Palmer J, Thompson SJ, Wilkins A, Webber DJ, Compston DA, Coles AJ
Brain, 2010-07-21;133(0):2232-47.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.
Authors: Carvajal-Vergara X, Sevilla A, D'Souza SL
Nature, 2010-06-10;465(7299):808-12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Selection and characterization of a human neutralizing antibody to human fibroblast growth factor-2.
Authors: Tao J, Xiang JJ, Li D, Deng N, Wang H, Gong YP
Biochem. Biophys. Res. Commun., 2010-03-17;394(3):767-73.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
Authors: Chng Z, Teo A, Pedersen RA, Vallier L
Cell Stem Cell, 2010-01-08;6(1):59-70.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Enoxaparin improves the course of dextran sodium sulfate-induced colitis in syndecan-1-deficient mice.
Authors: Floer M, Gotte M, Wild MK, Heidemann J, Gassar ES, Domschke W, Kiesel L, Luegering A, Kucharzik T
Am. J. Pathol., 2009-12-11;176(1):146-57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is downregulated in aggressive clinical disease.
Authors: Darby S, Murphy T, Thomas H, Robson CN, Leung HY, Mathers ME, Gnanapragasam VJ
Br. J. Cancer, 2009-11-03;101(11):1891-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Mitogen-activated protein kinase-signaling regulates the ability of Muller glia to proliferate and protect retinal neurons against excitotoxicity.
Authors: Fischer AJ, Scott MA, Ritchey ER, Sherwood P
Glia, 2009-11-01;57(14):1538-52.
Species: Chicken
Sample Types: In Vivo
Applications: In Vivo -
Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma.
Authors: Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D
Int. J. Cancer, 2009-09-01;125(5):1092-101.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Characterization of human skin-derived mesenchymal stem cell proliferation rate in different growth conditions.
Authors: Riekstina U, Muceniece R, Cakstina I, Muiznieks I, Ancans J
Cytotechnology, 2009-02-14;58(3):153-62.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
Stem Cells, 2009-02-01;27(2):341-51.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Growth factor regulation of growth factors in articular chondrocytes.
Authors: Shi S, Mercer S, Eckert GJ, Trippel SB
J. Biol. Chem., 2009-01-09;284(11):6697-704.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Efficient Serum-Free Derivation of Oligodendrocyte Precursors from Neural Stem Cell-Enriched Cultures.
Authors: Rao RC, Boyd J, Padmanabhan R, Chenoweth JG, McKay RD
Stem Cells, 2009-01-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Establishment of a transitory dorsal-biased window of localized Ca2+ signaling in the superficial epithelium following the mid-blastula transition in zebrafish embryos.
Authors: Ma LH, Webb SE, Chan CM, Zhang J, Miller AL
Dev. Biol., 2008-12-24;327(1):143-57.
Species: Zebrafish
Sample Types: Whole Cells
Applications: Bioassay -
Distinctions between fetal and adult human platelet-derived growth factor-responsive neural precursors.
Authors: Chojnacki A, Kelly JJ, Hader W, Weiss S
Ann. Neurol., 2008-08-01;64(2):127-42.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
Cell Stem Cell, 2008-06-05;2(6):602-12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A CXCL5- and bFGF-dependent effect of PDGF-B-activated fibroblasts in promoting trafficking and differentiation of bone marrow-derived mesenchymal stem cells.
Authors: Nedeau AE, Bauer RJ, Gallagher K, Chen H, Liu ZJ, Velazquez OC
Exp. Cell Res., 2008-04-25;314(11):2176-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
Nature, 2008-04-23;453(7194):524-8.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons.
Authors: Ladewig J, Koch P, Endl E, Meiners B, Opitz T, Couillard-Despres S, Aigner L, Brustle O
Stem Cells, 2008-04-17;26(7):1705-12.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery.
Authors: Kiprilov EN, Awan A, Desprat R, Velho M, Clement CA, Byskov AG, Andersen CY, Satir P, Bouhassira EE, Christensen ST, Hirsch RE
J. Cell Biol., 2008-03-10;180(5):897-904.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
MDR1 expression identifies human melanoma stem cells.
Authors: Keshet GI, Goldstein I, Itzhaki O, Cesarkas K, Shenhav L, Yakirevitch A, Treves AJ, Schachter J, Amariglio N, Rechavi G
Biochem. Biophys. Res. Commun., 2008-02-13;368(4):930-6.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival.
Authors: Dobson NR, Zhou YX, Flint NC, Armstrong RC
Glia, 2008-02-01;56(3):318-30.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation.
Authors: Patel VN, Likar KM, Zisman-Rozen S, Cowherd SN, Lassiter KS, Sher I, Yates EA, Turnbull JE, Ron D, Hoffman MP
J. Biol. Chem., 2008-01-28;283(14):9308-17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
Authors: Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L
Genes Dev., 2008-01-15;22(2):152-65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
A large-scale proteomic analysis of human embryonic stem cells.
Authors: Schulz TC, Swistowska AM, Liu Y
BMC Genomics, 2007-12-27;8(0):478.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
Nature, 2007-12-06;450(7171):825-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
Blood, 2007-11-27;111(4):1933-41.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Fractalkine, a CX3C chemokine, as a mediator of ocular angiogenesis.
Authors: You JJ, Yang CH, Huang JS, Chen MS, Yang CM
Invest. Ophthalmol. Vis. Sci., 2007-11-01;48(11):5290-8.
Species: Bovine, Human
Sample Types: Whole Cells
Applications: Bioassay -
Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis.
Authors: Patel VN, Knox SM, Likar KM, Lathrop CA, Hossain R, Eftekhari S, Whitelock JM, Elkin M, Vlodavsky I, Hoffman MP
Development, 2007-10-24;134(23):4177-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation.
Authors: Lu J, Jiang W, Yang JH, Chang PY, Walterscheid JP, Chen HH, Marcelli M, Tang D, Lee YT, Liao WS, Yang CY, Chen CH
Diabetes, 2007-10-24;57(1):158-66.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay -
Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling.
Authors: Wang L, Schulz TC, Sherrer ES, Dauphin DS, Shin S, Nelson AM, Ware CB, Zhan M, Song CZ, Chen X, Brimble SN, McLean A, Galeano MJ, Uhl EW, D'Amour KA, Chesnut JD, Rao MS, Blau CA, Robins AJ
Blood, 2007-08-29;110(12):4111-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
Authors: Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS
J. Biol. Chem., 2007-08-24;282(43):31643-55.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture conditions.
Authors: Inagaki A, Soeda A, Oka N, Kitajima H, Nakagawa J, Motohashi T, Kunisada T, Iwama T
Biochem. Biophys. Res. Commun., 2007-07-18;361(3):586-92.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
New cell lines from mouse epiblast share defining features with human embryonic stem cells.
Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
Nature, 2007-06-27;448(7150):196-9.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Conditional gene expression in human embryonic stem cells.
Authors: Vallier L, Alexander M, Pedersen R
Stem Cells, 2007-02-22;25(6):1490-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Differentiation of ES cells into cerebellar neurons.
Authors: Salero E, Hatten ME
Proc. Natl. Acad. Sci. U.S.A., 2007-02-09;104(8):2997-3002.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research.
Authors: Josephson R, Ording CJ, Liu Y, Shin S, Lakshmipathy U, Toumadje A, Love B, Chesnut JD, Andrews PW, Rao MS, Auerbach JM
Stem Cells, 2007-02-01;25(2):437-46.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
Authors: Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
Stem Cells, 2007-02-01;25(2):490-9.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Role for amplification and expression of glypican-5 in rhabdomyosarcoma.
Authors: Williamson D, Selfe J, Lu YJ, Pritchard-Jones K, Murai K, Jones P, Workman P, Shipley J
Cancer Res., 2007-01-01;67(1):57-65.
Species: Human, Xenopus
Sample Types: Whole Cells, Whole Tissue
Applications: Bioassay -
Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.
Authors: McLean AB, D&apos;Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, Sheppard AM, Liu H, Xu Y, Baetge EE, Dalton S
Stem Cells, 2007-01-01;25(1):29-38.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
Authors: Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
Br. J. Haematol., 2006-12-01;135(5):703-14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Neural conversion of human embryonic stem cell colonies in the presence of fibroblast growth factor-2.
Authors: Benzing C, Segschneider M, Leinhaas A, Itskovitz-Eldor J, Brustle O
Neuroreport, 2006-11-06;17(16):1675-81.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.
Authors: Nakayama T, Mutsuga N, Tosato G
Blood, 2006-10-31;109(4):1363-72.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium.
Authors: Bartunek J, Croissant JD, Wijns W, Gofflot S, de Lavareille A, Vanderheyden M, Kaluzhny Y, Mazouz N, Willemsen P, Penicka M, Mathieu M, Homsy C, De Bruyne B, McEntee K, Lee IW, Heyndrickx GR
Am. J. Physiol. Heart Circ. Physiol., 2006-10-20;292(2):H1095-104.
Species: Canine, Human
Sample Types: Whole Cells
Applications: Bioassay -
Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
Authors: Greber B, Lehrach H, Adjaye J
Stem Cells, 2006-10-12;25(2):455-64.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1.
Authors: Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D
J. Biol. Chem., 2006-10-06;281(49):37844-52.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Expression of leukemia inhibitory factor and its receptors is increased during differentiation of human embryonic stem cells.
Authors: Aghajanova L, Skottman H, Stromberg AM, Inzunza J, Lahesmaa R, Hovatta O
Fertil. Steril., 2006-09-01;86(4):1193-209.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.
Authors: Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM
Development, 2006-08-30;133(19):3787-96.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Multipotent adult progenitor cells from swine bone marrow.
Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
Stem Cells, 2006-08-24;24(11):2355-66.
Species: Porcine
Sample Types: Whole Cells
Applications: Bioassay -
Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats.
Authors: Kobayashi T, Ahlenius H, Thored P, Kobayashi R, Kokaia Z, Lindvall O
Stroke, 2006-07-27;37(9):2361-7.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay -
Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death.
Authors: Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M
J. Neurochem., 2006-07-01;98(1):45-56.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of murine adrenal chromaffin cell line tsAM5D.
Authors: Murata T, Tsuboi M, Hikita K, Kaneda N
J. Biol. Chem., 2006-06-13;281(32):22503-16.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Isolation of a novel population of multipotent adult stem cells from human hair follicles.
Authors: Yu H, Fang D, Kumar SM, Li L, Nguyen TK, Acs G, Herlyn M, Xu X
Am. J. Pathol., 2006-06-01;168(6):1879-88.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells.
Authors: Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB
Glia, 2006-06-01;53(8):845-57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
Stem Cells, 2006-05-25;24(9):2014-22.
Species: Primate - Callitrix jacchus (Common Marmoset)
Sample Types: Whole Cells
Applications: Bioassay -
Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration.
Authors: Li Y, Fan J, Chen M, Li W, Woodley DT
J. Invest. Dermatol., 2006-05-11;126(9):2096-105.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles.
Authors: Anghelina M, Krishnan P, Moldovan L, Moldovan NI
Am. J. Pathol., 2006-02-01;168(2):529-41.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Re-growth of catecholaminergic fibers and protection of cholinergic spinal cord neurons in spinal repaired rats.
Authors: Lee YS, Lin CY, Robertson RT, Yu J, Deng X, Hsiao I, Lin VW
Eur. J. Neurosci., 2006-02-01;23(3):693-702.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo -
Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.
Authors: Narazaki M, Tosato G
Blood, 2006-01-19;107(10):3892-901.
Applications: ELISA (Standard) -
Heterodimerization of FGF-receptor 1 and PDGF-receptor-alpha: a novel mechanism underlying the inhibitory effect of PDGF-BB on FGF-2 in human cells.
Authors: Faraone D, Aguzzi MS, Ragone G, Russo K, Capogrossi MC, Facchiano A
Blood, 2005-12-01;107(5):1896-902.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells.
Authors: Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL, Chang YJ
Biol. Reprod., 2005-11-23;74(3):545-51.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis.
Authors: Shin JW, Min M, Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L, Henderson JE, Bikfalvi A, Detmar M, Hong YK
Mol. Biol. Cell, 2005-11-16;17(2):576-84.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Pericytes and endothelial precursor cells: cellular interactions and contributions to malignancy.
Authors: Bagley RG, Weber W, Rouleau C, Teicher BA
Cancer Res., 2005-11-01;65(21):9741-50.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Application of plasmid DNA encoding IL-18 diminishes development of herpetic stromal keratitis by antiangiogenic effects.
Authors: Kim B, Lee S, Suvas S, Rouse BT
J. Immunol., 2005-07-01;175(1):509-16.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Novel regulators of kidney development from the tips of the ureteric bud.
Authors: Schmidt-Ott KM, Yang J, Chen X, Wang H, Paragas N, Mori K, Li JY, Lu B, Costantini F, Schiffer M, Bottinger E, Barasch J
J. Am. Soc. Nephrol., 2005-05-25;16(7):1993-2002.
Species: Rat
Sample Types: Whole Tissue
Applications: Bioassay -
Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta.
Authors: Nagineni CN, Kutty V, Detrick B, Hooks JJ
J. Cell. Physiol., 2005-04-01;203(1):35-43.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Transitin, a nestin-related intermediate filament, is expressed by neural progenitors and can be induced in Muller glia in the chicken retina.
Authors: Fischer AJ, Omar G
J. Comp. Neurol., 2005-03-28;484(1):1-14.
Species: Chicken
Sample Types: In Vivo
Applications: In Vivo -
FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis.
Authors: Steinberg Z, Myers C, Heim VM, Lathrop CA, Rebustini IT, Stewart JS, Larsen M, Hoffman MP
Development, 2005-02-16;132(6):1223-34.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
Different aspects of gliosis in retinal Muller glia can be induced by CNTF, insulin, and FGF2 in the absence of damage.
Authors: Fischer AJ, Omar G, Eubanks J, McGuire CR, Dierks BD, Reh TA
Mol. Vis., 2004-12-22;10(0):973-86.
Species: Chicken
Sample Types: In Vivo
Applications: In Vivo -
High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells.
Authors: Ni HT, Hu S, Sheng WS, Olson JM, Cheeran MC, Chan AS, Lokensgard JR, Peterson PK
Brain Res. Dev. Brain Res., 2004-09-17;152(2):159-69.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
Authors: Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J
Arthritis Rheum., 2004-08-01;50(8):2521-30.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
Blood, 2004-03-25;104(2):314-20.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Angiostatin-induced inhibition of endothelial cell proliferation/apoptosis is associated with the down-regulation of cell cycle regulatory protein cdk5.
Authors: Sharma MR, Tuszynski GP, Sharma MC
J. Cell. Biochem., 2004-02-01;91(2):398-409.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay -
Growth differentiation factor-9 and stem cell factor promote primordial follicle formation in the hamster: modulation by follicle-stimulating hormone.
Authors: Wang J, Roy SK
Biol. Reprod., 2003-10-29;70(3):577-85.
Species: Hamster
Sample Types: Whole Cells
Applications: Bioassay -
Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity.
Authors: Yi M, Sakai T, Fassler R, Ruoslahti E
Proc. Natl. Acad. Sci. U.S.A., 2003-09-17;100(20):11435-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
Authors: Kovalenko D, Yang X, Nadeau RJ, Harkins LK, Friesel R
J. Biol. Chem., 2003-02-24;278(16):14087-91.
Species: Human, Mouse, Primate - Chlorocebus pygerythrus (Vervet Monkey)
Sample Types: Whole Cells
Applications: Bioassay -
Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3.
Authors: Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC
Cancer Res., 2003-02-15;63(4):887-92.
Species: Human
Sample Types: Whole Cells
Applications: Binding Assay -
Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells.
Authors: Bandyopadhyay A, 2019, Zhu Y, Malik SN, Kreisberg J, Brattain MG, Sprague EA, Luo J, Lopez-Casillas F, Sun LZ
101205, 2002-05-16;21(22):3541-51.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo
FAQs
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What receptors does FGF basic bind?
FGF receptor specificity has been reviewed in multiple citations. Please find more information at: //www.rndsystems.com/resources/articles/fibroblast-growth-factors-and-their-receptors
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Does human FGF basic show activity on mouse cells?
Yes, it does. The bioassay uses NR-6 mouse fibroblast cells. There is 95% homology between the human and mouse protein and 98% homology between the human and mouse receptor.
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