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Basement Membrane Extract (also referred to as BME, extracellular matrix (ECM), or basement membrane hydrogel) is used globally for culture applications including organoid generation and pluripotent stem cell expansion. While BME is universally utilized as a scaffolding matrix for 2D and 3D cell culture, researchers spend tremendous amounts of effort testing and identifying specific lots of matrix that work for their cells. It can be frustrating and very time consuming.

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We recognize the vital impact of quality fetal bovine serum for today’s evolving cell culture needs. With over 40 years of rigorous research, development, and manufacturing at our ISO 9001:2105 certified facility, R&D Systems has produced an industry-leading portfolio of fetal bovine serum (FBS). Following R&D Systems reputation for product quality, our FBS portfolio emphasizes excellence in cell culture performance, serum traceability, lot-to-lot consistency, and product availability.

With dedicated raw serum suppliers of United States origin and USDA-approved, Central American FBS, R&D Systems has direct access to a secure supply of FBS to...

Flow cytometry is a powerful technique that allows researchers to examine multiple proteins on cell populations using fluorescently labeled antibodies. Multi-parameter, fluidic-based flow cytometry has been applied to multiple fields of study ranging from basic to clinical immunology, cancer biology, neuroscience, stem cell research, and drug discovery. In order to maximize the quality of results obtained using this technology, researchers should be familiar with the basics of flow cytometry when setting up an experiment. In this series of seminars, we will discuss the necessary tools to design, run, and analyze a multi-parameter flow cytometric experiment.

Webinar 2 - Turning Flow Cytometry Upside Down and Inside Out: Cellular Function Revealed

In this webinar, you will learn how to apply basic concepts of flow cytometry to...

https://origin-rndsystemsstg.corpenttech.com/blog/stem-cells-news-february-2019

We have captured this month’s most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.

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Bio-Techne’s Go Everywhere Travel Grant Program awards $1000 USD (or equivalent) to one researcher each month to attend the meeting of their choice. This grant program allows the researcher to attend more targeted meetings in their field and provides funding to support both small and large scientific associations that promote discovery and collaboration.

The recipient of the March 2019 grant is Jorieke Weiden, a Postdoctoral Researcher in the Tumor Immunology department at Radboud University Medical Center in Nijmegen, Netherlands.

Bio-Techne’s ...

Featured speakers:

J. Joseph Melenhorst, Ph.D., University of Pennsylvania

Laurence J. N. Cooper, M.D., Ph.D., Ziopharm Oncology

Moderated by:

Sean Sanders, Ph.D., Science/AAAS

The field of immuno-oncology has exploded in the clinic, in the press, and on Wall Street, particularly regarding the use of genetically modified immune cells to fight cancer. This “explosion” is largely due to the success of chimeric antigen receptor (CAR) T-cell therapy. The fields of immunology and gene therapy have converged to harness recombinant viruses to deliver “living drugs” with remarkable clinical efficacy, especially for patients with blood cancers. Multiple approaches to engineer immune cells—mostly T cells but also other immune cell types—make use of CARs, while tumor-specific T-cell receptors continue to gain a foothold...

The monoclonal antibody therapy market is rapidly expanding with all major pharmaceutical companies seeking approval of more antibody drug modalities each year. In addition, many of the blockbuster monoclonal therapeutics are nearing the end of their patents and the opportunity for biosimilars looms in the marketplace.

Researchers look to anti-idiotype antibodies to study new monoclonal therapeutic candidates, to better understand the efficacy of existing monoclonal therapeutics and to evaluate the development of biosimilars. An anti-idiotype (anti-ID) antibody is specific to the unique antigen binding (variable) region of another antibody. In this case, the anti-idiotype is specific to the monoclonal therapeutic or its biosimilar.

R...

https://origin-rndsystemsstg.corpenttech.com/blog/stem-cells-news-february-2019

We have captured this month’s most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.

Bio-Techne’s Go Everywhere Travel Grant Program awards $1000 USD (or equivalent) to one researcher each month to attend the meeting of their choice. This grant program allows the researcher to attend more targeted meetings in their field and provides funding to support both small and large scientific associations that promote discovery and collaboration.

The recipient of the December 2018 'Go Everywhere Travel Grant' is Samantha Jones, a PhD Candidate in Medical Genetics at the University of British Columbia, in Vancouver, British Columbia, Canada. Samantha has chosen to apply the grant to attend the 25th Biennial Congress of the European Association for Cancer Research in Amsterdam, the Netherlands on...

We have captured this month’s most interesting, innovative, and maybe some of the strangest examples of stem cells in the news from around the world.