Human SLITRK2 Antibody

Catalog # Availability Size / Price Qty
AF2657
AF2657-SP
Product Details
Citations (1)
FAQs
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Human SLITRK2 Antibody Summary

Species Reactivity
Human
Specificity
Detects human SLITRK2 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross‑reactivity with recombinant human (rh) SLITRK4 is observed and less than 2% cross-reactivity with rhSLITRK1 and rhSLITRK5 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human SLITRK2
Thr19-Pro617
Accession # Q9H156
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human SLITRK2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SLITRK2

SLITRK2 is a type I membrane protein belonging to the SLITRK family of neuronal proteins that modulate neurite outgrowth. The 600 amino acid residue extracellular domain of SLITRK2 has two conserved leucine-rich repeat domains with homology to SLIT. The 200 aa cytoplasmic domain also shares similarity to TRK neurotrophin receptor proteins. The extracellular domain of human SLITRK shares 98% amino acid sequence identity with the extracellular domains of rat, mouse and canine SLITRK2.

Long Name
SLIT and NTRK-like Family, Member 2
Entrez Gene IDs
84631 (Human); 245450 (Mouse)
Alternate Names
CXorf2; SLITL1; SLITRK2 SLIT and NTRK-like family, member 2; SLITRK2

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Citation for Human SLITRK2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Slitrk2 deficiency causes hyperactivity with altered vestibular function and serotonergic dysregulation
    Authors: Kei-ichi Katayama, Naoko Morimura, Katsunori Kobayashi, Danielle Corbett, Takehito Okamoto, Veravej G. Ornthanalai et al.
    iScience

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