MCAM/CD146: Products
MCAM, also known as MUC18, is an Ig-superfamily glycoprotein that shows significant homology to several cell adhesion molecules, notably N-CAM. It was identified as an antigen on metastatic melanoma cells and is also expressed on a variety of normal and transformed cell types. MCAM expression is associated with tumor progression and metastasis, and may be involved in embryonic neuronal development.
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