VEGF-C: Products
Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.
Products:
- Proteins & Enzymes
- Primary Antibodies
- Simple Plex Assays
- ELISAs
- Luminex Assays
- Proteome Profiler Antibody Arrays
Show More
"VEGF-C" has 12 results in Products.
Sort by:
Simple Plex Human VEGF-C Cartridge
Simple Plex Human VEGF-C assay kit for use on Ella instrument. Contains cartridge, sample diluent SD10, and wash buffer.
Proteome Profiler Human Angiogenesis Array Kit
Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies
Custom Simple Plex™ Assay Panels
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
page
of
1