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"IL-8" has 23 results in Resources.

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IL-8 and Metastasis

Article

Tumor cell metastasis is a complex, multi-step process. In order to metastasize, a tumor cell must be able to invade surrounding tissue, disseminate via the lymphatic system or bloodstream, extravasate and subsequently proliferate at a secondary location. Cytokines/growth factors play an important role in tumor cell metastasis by promoting, for example, tumor cell proliferation, adhesion,...

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TNF Superfamily Proteins

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We offer the widest selection high quality, bioactive TNF Superfamily proteins in the life sciences industry. These include an array of ligands and receptors, many of which are exclusive to R&D Systems. Click the buttons below to learn about our new and improved TNF Superfamily proteins. New Proteins Biotinylated Human TNF-alpha Human GMP-grade TNF-alpha Mouse DcTRAIL...

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Sample Data: Human Cytokine Array, Panel A

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Location Analyte Location Analyte A1 PC C6 IL-17 A2 C5a C7 IL-17E A3 CD40...

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Chemokines I

Article

First printed in R&D Systems' 1997 Catalog. Figure 1. M-trophic HIV-1 & chemokine receptors. 1. gp120 and gp41 are formed intracellularly by the cleavage of a 160 kDa precursor; The two subunits heterodimerize non-covalently. 2. CD4 binds to gp120 binding sites distributed along the C-terminal region of gp120. 3. Following binding to CD4, plus a change in gp120 conformation, V3...

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Chemokines I

Article

First printed in R&D Systems' 1997 Catalog. Figure 1. M-trophic HIV-1 & chemokine receptors. 1. gp120 and gp41 are formed intracellularly by the cleavage of a 160 kDa precursor; The two subunits heterodimerize non-covalently. 2. CD4 binds to gp120 binding sites distributed along the C-terminal region of gp120. 3. Following binding to CD4, plus a change in gp120 conformation, V3...

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LI-COR Data Examples for Human XL Cytokine Array Kit

Technical Resource

Data Examples Profiling Proteins in Cell Culture Supernates Figure 1. The Human XL Cytokine Array detects multiple analytes in cell culture supernates. HUVEC human umbilical vein endothelial cells were untreated or treated with 100 μg/mL recombinant human TNF-alpha (R&D Systems, Catalog # 210-TA) for 24 hours In each array shown, 500 µL of cell supernate was used. Array images were...

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Human Cytokine Array Kit

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Human Cytokine Array Kit, Panel A Ordering Information Introduction R&D Systems Human Cytokine Array, Panel A (Catalog # ARY005B) is a rapid, sensitive, and economical tool used to simultaneously detect the relative levels of 36 different cytokines, chemokines, and acute-phase proteins in a single sample. No specialized equipment is necessary. Proteome Profiler Antibody Arrays Use of...

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Technical Notes: Assay Precision Impact of Salivary Cytokine Contamination

Article

Mask Worn No Mask Worn Figure 1. The plate on the left was run by an operator wearing a mask, while the plate on the right was run by an operator without a mask and talking while running the assay (note: both plates were run with the same mid-level standard). A number of studies have documented the presence of endogenous levels of cytokines and related...

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IL-17 is Produced by T-cells

Article

Its Receptor is Widespread The name IL-17 has been assigned to a T-cell-produced protein that acts on receptors expressed by a wide variety of cells.1,2 The sequence first was identified as CTLA8 from a murine cDNA sequence obtained by subtractive hybridization of activated T-cells.3 CTLA8 was 57% homologous with open reading frame 13 of Herpesvirus saimiri (HVS13),4 a lymphotropic virus....

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Regakine-1: An Abundant Serum Chemokine

Article

Regakine-1, a novel CC chemokine recently identified in bovine serum, shares less than 50% identity with any known human chemokine.1 Amino acid (aa) sequence alignment of Regakine-1 demonstrates that it is most homologous to human eotaxin. It lacks common eotaxin residues, however, shared among other species. The 7.5 kDa, 70 aa protein has weak chemotactic activity for neutrophils and lymphocytes...

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