"cd30" has 17 results in Resources.

Several TNF superfamily members play key roles in early B cell maturation, homeostasis, differentiation, and activation. While BAFF R is required for normal B cell maturation, interactions between BAFF-BAFF R, BAFF-TACI, APRIL-BCMA, and CD40 Ligand-CD40 promote B cell differentiation and homeostasis. The interaction between CD40 Ligand and CD40 is necessary for germinal center B cell...

Is your array being completely honest with you? Eliminate false positives using Proteome Profiler™ Antibody Arrays. Antibody specificity is a keystone of any array. Make sure your array is delivering accurate results. As indicated in the table below, there are several spots in the competitor's array that aren't exactly what they say they are. When confirmed by Quantikine® ELISA, the industry...

Analyte DuoSet® and DuoSet IC ELISA Development Systems Quantikine® ELISA...

Activate Co-stimulatory Molecules Immune checkpoint blockade strategies are starting to be complemented by the addition of co-stimulatory molecule agonism with the goal of generating a more robust anti-tumor response. This approach warrants further investigation in order to find optimal combinations of targets and better inform future therapeutic options. Find the agonistic antibodies and small...

T cell activation requires two signals from antigen-presenting cells (APCs). The antigen-specific major histocompatibility complex (MHC) signal is mediated via the interaction between the antigen-MHC complex localized on the surface of APCs and the T cell receptor localized on the surface of T cells. The non-antigen specific, co-stimulatory signal occurs via the interactions between stimulatory...

Upon activation, natural killer (NK) cells secrete cytotoxic and inflammatory cytokines that cause apoptosis or lysis of targeted cells. While some pathogens can directly activate NK cells, NK cells are indirectly activated in response to most pathogens by accessory cells. Several TNF superfamily members have been implicated in mediating NK cell activation and regulation by accessory cells. These...

Lymphomas are a class of hematologic cancers that arise from a lymphocyte progenitor and develop in lymphatic tissues rather than in the bone marrow. Lymphomas often present as solid tumors composed of a variety of immune cells including lymphocytes, eosinophils, neutrophils, and histiocytes. Historically, lymphomas have been classified as Hodgkin's lymphoma or non-Hodgkin's lymphoma (NHL)....

Human sReceptor Array Kit Hematopoietic Panel Ordering Information Introduction R&D Systems Human Soluble Receptor Array Kit Hematopoietic Panel (Catalog # ARY011) is a rapid, sensitive, and economical tool used to simultaneously detect the relative levels of 105 different soluble receptors expressed and released by hematopoietic cells in a single sample. No specialized equipment is...

First printed in R&D Systems' 1998 Catalog. Figure 1: TNF Superfamily involving Fas/FasL and CD40/CD40L. Overview The first suggestion that a tumor necrotizing molecule existed was made when it was observed that cancer patients occasionally showed spontaneous regression of their tumors following bacterial infections.1 Subsequent studies in the 1960s indicated that...

Analyte Quantikine® ELISA Kit DuoSet® ELISA Development System Adiponectin/Acrp30 DRP300,...