Is your array being completely honest with you? Eliminate false positives using Proteome Profiler™ Antibody Arrays.
Antibody specificity is a keystone of any array. Make sure your array is delivering accurate results. As indicated in the table below, there are several spots in the competitor's array that aren't exactly what they say they are. When confirmed by Quantikine® ELISA, the industry gold standard, these targets were shown to be either false positives or false negatives. Count on R&D Systems for consistent data every time.
| Analyte | Proteome Profiler™ Array |
Competitor Array |
| HGF | + | false negative |
| IGFBP-5 | + | + |
| IL-1 alpha/IL-1F1 | - | false positive |
| IL-3 | - | false positive |
| IL-11 | - | false positive |
| IL12-P40 | - | false positive |
| MMP-2 | + | + |
| Osteopontin | + | + |
| All samples confirmed by R&D Systems Quantikine ELISA | ||
| Analyte | Proteome Profiler™ Array |
Competitor Array |
| CCL19/MIP-3 beta | - | false positive |
| CCL20/MIP-3 alpha | - | false positive |
| CCL21/6 Chemokine | + | false negative |
| CXCL2/MIP-2 | - | false positive |
| CXCL13/BLC/BCA-1 | + | false negative |
| DKK-1 | + | false negative |
| EGF | + | + |
| All samples confirmed by R&D Systems Quantikine ELISA | ||
Have you done a background check on your array?
Proteome Profiler™ Antibody Arrays have cleaner backgrounds than the competition.
Proteome Profiler Arrays have noticeably lower background than the competition. By using the highest quality antibodies, highly specialized buffers, as well as a more reliable chemiluminescent detection system, Proteome Profiler Arrays make it easier to run a clean array and recover useable data. Don’t lose valuble data because of high background.
Don't let your results disappear on you! Avoid post-exposure signal loss!
The stability of your detection system is critical when the results are being recorded onto film. Our competitor's arrays can lose signal very rapidly, giving you a limited window of time to achieve the best result. Proteome Profiler™ Arrays always deliver a robust and stable signal that can be used to make multiple consecutive exposures, giving you increased flexibility to record your results.
Is your array conflicted? End array cross-reactivity issues by using
Proteome Profiler™ Antibody Arrays.
Uninterpretable data can occur when the selected array targets are not well thought out. Some competitors include both receptors and their ligands, which increases the likelihood of cross-reactivity. Proteome Profiler™ Arrays are painstakingly curated to eliminate cross-reactivity. It's not just about giving you more results, it's about giving you better results.
| Analyte | Cross-reactive analyte |
| IL-2 | IL-2R alpha |
| IL-12p40 | IL-12p70 |
| Leptin | Leptin Receptor |
| TNF-alpha | TNFR1, TNFRII, TRANCE |
| VEGF | VEGFR1, VEGFR3,VEGF-D |
| CD27 Ligand | CD27 |
| CD30 Ligand | CD30 |
| GITR Ligand | GITR |
