Valukine ELISA试剂盒 References

References

VAL101
Number	Title	Journal	Species	Sample Types
1	Understanding the molecular pathway of triclosan-induced ADHD-like behavior: Involvement of the hnRNPA1-PKM2-STAT3 feedback loop	Environ Int. 2024 Sep:191:108966	Human	Cell culture supernatant
2	Hypermethylation of the glutathione peroxidase 4 promoter predicts poor prognosis in patients with hepatitis B virus-associated acute-on-chronic liver failure	Front Mol Biosci. 2024 Jul 25:11:1421597	Human	serum
3	DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease	Signal Transduct Target Ther. 2024 Jun 17;9(1):163	Human	Cell culture supernatant
4	Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B	Virol J. 2024 Mar 21;21(1):72	Human	serum
5	Upregulation of CD39 During Gout Attacks Promotes Spontaneous Remission of Acute Gouty Inflammation	Inflammation.2024 Apr;47(2):664-677	Human	Cell culture supernatant
6	Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer	EMBO Mol Med. 2022 Jan 11;14(1):e14502	Human	Cell culture supernatants
7	Two new 7, 20-epoxy- ent-kauranes from the aerial parts of Isodon eriocalyx	Nat Prod Res. 2021 Nov;35(21):3859-3864	Human	cell supernatant
8	SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation	Front Immunol. 2021 Feb 23;12:595140	Human	cell supernatant
9	IL-1/IL-1R signaling induced by all-trans-retinal contributes to complement alternative pathway activation in retinal pigment epithelium	J Cell Physiol. 2021 May;236(5):3660-3674	Human	Cell culture supernatants
10	Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor	Autophagy. 2021 Oct;17(10):3011-3029	Human	serum, cell culture supernatants
11	The Role of Caspase-4 and NLRP1 in MCF7 Cell Pyroptosis Induced by hUCMSC-Secreted Factors	Stem Cells Int. 2020 Jul 9;2020:8867115	Human	Cell culture supernatants
12	Fine Particulate Matter (PM2.5) upregulates expression of Inflammasome NLRP1 via ROS/NF-κB signaling in HaCaT Cells	Int J Med Sci. 2020 Sep1;17(14):2200-2206	Human	Cell culture supernatants
13	Circulatory CD4-Positive T-Lymphocyte Imbalance Mediated by Homocysteine-Induced AIM2 and NLRP1 Inflammasome Upregulation and Activation Is Associated with Human Abdominal Aortic Aneurysm	J Vasc Res. 2020;57(5):276-290	Human	cell supernatant
14	MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8	Int Immunopharmacol. 2020 Mar;80:106197	Human	Cell culture supernatants
15	microRNA-21 Aggravates Lipopolysaccharide-Induced Inflammation in MH7A Cells Through Targeting SNF5	Inflammation. 2020 Apr;43(2):441-454	Human	Cell culture supernatants
16	Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China	Environ Int. 2020 Jun;139:105703	Human	Cell culture supernatants
16	7-Ketocholesterol disturbs RPE cells phagocytosis of the outer segment of photoreceptor and induces inflammation through ERK signaling pathway	Exp Eye Res. 2019 Dec;189:107849	Human	cell media
17	Retinal Pigment Epithelium Cell Death Is Associated With NLRP3 Inflammasome Activation by All-trans Retinal	Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):3034-3045	Human	cell culture supernatants
18	Profiling and functional characterization of circulation LncRNAs that are associated with coronary atherosclerotic plaque stability	Am J Transl Res. 2019 Jun 15;11(6):3801-3815	Human	cell culture supernatants
19	NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester	Cell Biochem Funct. 2019 Oct;37(7):464-473	Human	cell culture supernatants
20	Downregulation of GSDMD attenuates tumor proliferation via the intrinsic mitochondrial apoptotic pathway and inhibition of EGFR/Akt signaling and predicts a good prognosis in non‑small cell lung cancer	Oncol Rep. 2018 Oct;40(4):1971-1984	Human	cell culture supernatants
21	Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis	Front Immunol. 2018 Jun 4;9:1197	Human	cell supernatant
22	Pyroptosis of MCF7 Cells Induced by the Secreted Factors of hUCMSCs	Stem Cells Int. 2018 Nov 11;2018:5912194	Human	cell culture supernatants
23	Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation	J Biol Chem. 2015 Jul 17;290(29):18018-18028	Human	cell culture supernatants
24	Inhibition of STAT5a by Naa10p contributes to decreased breast cancer metastasis	Carcinogenesis. 2014 Oct;35(10):2244-53	Human	cell culture supernatants
25	Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced inflammasome activation in human gingival epithelial cells	Int J Mol Med. 2014 Oct;34(4):1039-44	Human	cell culture medium
26	Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy	PLoS One. 2014 Jun 16;9(6):e99612	Human	cell culture supernatants
27	Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells	APMIS.2014 Nov;122(11):1059-69	Human	cell culture supernatants
28	Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation	Int J Biochem Cell Biol. 2014 Dec;57:7-19	Human	cell culture supernatants

VAL102C
Number	Title	Journal	Species	Sample Types
1	Association analysis of MTHFR (rs1801133 and rs1801131) gene polymorphism towards the development of type 2 diabetes mellitus in Dali area population from Yunnan Province, China	PeerJ. 2024 Oct 24:12:e18334	Human	serum
2	Understanding the molecular pathway of triclosan-induced ADHD-like behaviour: Involvement of the hnRNPA1-PKM2-STAT3 feedback loop	Environ Int. 2024 Sep:191:108966	Human	Cell culture supernatants
3	Hypermethylation of the glutathione peroxidase 4 promoter predicts poor prognosis in patients with hepatitis B virus-associated acute-on-chronic liver failure	Front Mol Biosci. 2024 Jul 25:11:1421597	Human	serum
4	Metochalcone induces senescence-associated secretory phenotype via JAK2/STAT3 pathway in breast cancer	Oncol Res. 2024 Apr 23;32(5):943-953	Human	Cell culture supernatants
5	Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B	Virol J. 2024 Mar 21;21(1):72	Human	serum
6	Upregulation of CD39 During Gout Attacks Promotes Spontaneous Remission of Acute Gouty Inflammation	Inflammation. 2024 Apr;47(2):664-677	Human	Cell culture supernatant
7	BR109, a Novel Fully Humanized T-Cell-Engaging Bispecific Antibody with GPRC5D Binding, Has Potent Antitumor Activities in Multiple Myeloma	Cancers (Basel). 2023 Dec 9;15(24):5774	Human	Cell culture supernatants
8	Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis.	Cell Rep. 2023 Aug 29;42(8):112944.	Human	Cell culture supernatants
9	Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy	BMC Nephrol. 2022 Jan 11;23(1):25	Human	cell culture supernatants
10	RNA circles with minimized immunogenicity as potent PKR inhibitors	Mol Cell. 2022 Jan 20;82(2):420-434.e6	Human	cell culture supernatants
11	Reveals of quercetin's therapeutic effects on oral lichen planus based on network pharmacology approach and experimental validation	Sci Rep. 2022 Jan 21;12(1):1162	Human	cell culture supernatants
12	Phenformin Down-Regulates c-Myc Expression to Suppress the Expression of Pro-Inflammatory Cytokines in Keratinocytes	Cells. 2022 Aug 5;11(15):2429	Human	cell culture supernatants
13	SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation	Front Immunol. 2021 Feb 23;12:595140	Human	cell supernatant
14	Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway	Front Oncol. 2020 Apr 21;10:624	Human	cell culture medium
15	1α,25-dihydroxyvitamin D3 promotes early osteogenic differentiation of PDLSCs and a 12-year follow-up case of early-onset vitamin D deficiency periodontitis	J Steroid Biochem Mol Biol. 2021 Apr;208:105805	Human	cell culture supernatants
16	CagA orchestrates eEF1A1 and PKCδ to induce interleukin-6 expression in Helicobacter pylori-infected gastric epithelial cells	Gut Pathog. 2020 Jul 3;12:31	Human	cell culture supernatants
17	Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China	Environ Int. 2020 Jun;139:105703	Human	cell culture supernatants
18	MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8	Int Immunopharmacol. 2020 Mar;80:106197	Human	cell culture supernatants
19	microRNA-21 Aggravates Lipopolysaccharide-Induced Inflammation in MH7A Cells Through Targeting SNF5	Inflammation. 2020 Apr;43(2):441-454	Human	cell culture supernatants
20	Implication of inflammatory cytokines in the aqueous humour for management of macular diseases	Acta Ophthalmol. 2020 May;98(3):e309-e315	Human	aqueous humour
21	Immunomodulation‐Based Strategy for Improving Soft Tissue and Metal Implant Integration and Its Implications in the Development of Metal Soft Tissue Materials	Adv Funct Mater. 2020 March 20	Human	cell culture supernatants
22	Circulating soluble receptor for advanced glycation end products and other factors in type 2 diabetes patients with colorectal cancer	BMC Endocr Disord.2020 Nov 13;20(1):170	Human	serum
23	Inflammatory cytokines in highly myopic eyes	Sci Rep. 2019 Mar 5;9(1):3517	Human	aqueous humor
24	A novel tumor-promoting mechanism of IL6 and the therapeutic efficacy of tocilizumab: Hypoxia-induced IL6 is a potent autophagy initiator in glioblastoma via the p-STAT3-MIR155-3p-CREBRF pathway	Autophagy. 2016 Jul 2;12(7):1129-52	Human	serum, cell culture supernatants
25	Methylation of suppressor of cytokine signalling 1 gene promoter is associated with acute-on-chronic hepatitis B liver failure	J Viral Hepat. 2015 Mar;22(3):307-17	Human	plasma
26	Histone acetylation regulates orphan nuclear receptor NR4A1 expression in hypercholesterolaemia	Clin Sci (Lond). 2015 Dec;129(12):1151-61	Human	plasma,cell culture supernatants
27	Prognoses of patients with acute-on-chronic hepatitis B liver failure are closely associated with altered SOCS1 mRNA expression and cytokine production following glucocorticoid treatment	Cell Mol Immunol. 2014 Jul;11(4):396-404	Human	Plasma
28	Soluble interleukin-6 receptor-mediated innate immune response to DNA and RNA viruses	J Virol. 2013 Oct;87(20):11244-54	Human	cell culture supernatants

VAL103
Number	Title	Journal	Species	Sample Types
1	DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease	Signal Transduct Target Ther. 2024 Jun 17;9(1):163	Human	Cell culture supernatant
2	Changes in Serum Interleukin-8 Levels Predict Response to Immune Checkpoint Inhibitors Immunotherapy in Unresectable Hepatocellular Carcinoma Patients	J Inflamm Res. 2024 May 25:17:3397-3406	Human	serum
3	Metochalcone induces senescence-associated secretory phenotype via JAK2/STAT3 pathway in breast cancer	Oncol Res. 2024 Apr 23;32(5):943-953	Human	Cell culture supernatants
4	Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis.	Cell Rep. 2023 Aug 29;42(8):112944	Human	Cell culture supernatants
5	Phenformin Down-Regulates c-Myc Expression to Suppress the Expression of Pro-Inflammatory Cytokines in Keratinocytes	Cells. 2022 Aug 5;11(15):2429	Human	cell culture supernatants
6	Reversal of NADPH Oxidase-Dependent Early Oxidative and Inflammatory Responses in Chronic Obstructive Pulmonary Disease by Puerarin	Oxid Med Cell Longev. 2022 Apr 25;2022:5595781	Human	cell culture supernatants
7	Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway	Front Oncol. 2020 Apr 21;10:624	Human	cell culture medium
8	Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells	Exp Ther Med. 2019 Sep;18(3):1551-1562	Human	cell culture supernatants
9	Screening probiotics from Lactobacillus strains according to their abilities to inhibit pathogen adhesion and induction of pro-inflammatory cytokine IL-8	J Dairy Sci. 2018 Jun;101(6):4822-4829	Human	Cell culture supernatants
10	PKC/NADPH oxidase are involved in the protective effect of pioglitazone in high homocysteine-induced paracrine dyfunction in endothelial progenitor cells	Am J Transl Res. 2017 Mar 15;9(3):1037-1048	Human	Cell culture supernatants
11	Membrane cholesterol plays an important role in enteropathogen adhesion and the activation of innate immunity via flagellin-TLR5 signaling	Arch Microbiol. 2015 Aug;197(6):797-803	Human	Cell culture supernatants
12	Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells	APMIS.2014 Nov;122(11):1059-69	Human	Cell culture supernatants

VAL104C
Number	Title	Journal	Species	Sample Types
1	BR109, a Novel Fully Humanized T-Cell-Engaging Bispecific Antibody with GPRC5D Binding, Has Potent Antitumor Activities in Multiple Myeloma	Cancers (Basel). 2023 Dec 9;15(24):5774	Human	Cell culture supernatants
2	Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment	Cell Metab.2023 Jun 6;35(6):961-978.e10.	Human	Cell culture supernatants
3	Reveals of quercetin's therapeutic effects on oral lichen planus based on network pharmacology approach and experimental validation	Sci Rep. 2022 Jan 21;12(1):1162	Human	Cell culture supernatants
4	TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss	Cancer Cell Int. 2021 Apr 17;21(1):223	Human	Cell culture supernatants
5	High-throughput functional screening for next-generation cancer immunotherapy using droplet-based microfluidics	Sci Adv. 2021 Jun 11;7(24):eabe3839	Human	cell supernatant
6	NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester	Cell Biochem Funct. 2019 Oct;37(7):464-473	Human	Cell culture supernatants
7	Optimized DNA electroporation for primary human T cell engineering	BMC Biotechnol. 2018 Jan 30;18(1):4	Human	Cell culture supernatants
8	Abrasive Endoprosthetic Wear Particles Inhibit IFN-γ Secretion in Human Monocytes Via Upregulating TNF-α-Induced miR-29b	Inflammation. 2017 Feb;40(1):166-173	Human	Cell culture supernatants
9	Characterization of the subsets of human NKT-like cells and the expression of Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion	J Reprod Immunol. 2015 Aug;110:81-8	Human	Cell culture medium
10	Methylation of suppressor of cytokine signaling 1 gene promoter is associated with acute-on-chronic hepatitis B liver failure	J Viral Hepat. 2015 Mar;22(3):307-17	Human	plasma
11	Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy	PLoS One. 2014 Jun 16;9(6):e99612	Human	Cell culture supernatants

VAL105G
Number	Title	Journal	Species	Sample Types
1	Association analysis of MTHFR (rs1801133 and rs1801131) gene polymorphism towards the development of type 2 diabetes mellitus in Dali area population from Yunnan Province, China	PeerJ. 2024 Oct 24:12:e18334	Human	serum
2	Hypermethylation of the glutathione peroxidase 4 promoter predicts poor prognosis in patients with hepatitis B virus-associated acute-on-chronic liver failure	Front Mol Biosci. 2024 Jul 25:11:1421597	Human	serum
3	BR109, a Novel Fully Humanized T-Cell-Engaging Bispecific Antibody with GPRC5D Binding, Has Potent Antitumor Activities in Multiple Myeloma	Cancers (Basel). 2023 Dec 9;15(24):5774	Human	Cell culture supernatants
4	Upregulation of CD39 During Gout Attacks Promotes Spontaneous Remission of Acute Gouty Inflammation	Inflammation. 2024 Apr;47(2):664-677	Human	Cell culture supernatant
5	Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation	Front Pharmacol. 2022 Aug 16;13:979939	Human	Cell culture supernatants
6	Withaphysalins from Medicinal and Edible Physalis minima and Their Anti-inflammatory Activities	J Agric Food Chem. 2022 May 11;70(18):5595-5609	Human	Cell culture supernatants
7	Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy	BMC Nephrol. 2022 Jan 11;23(1):25	Human	Cell culture supernatants
8	Phenformin Down-Regulates c-Myc Expression to Suppress the Expression of Pro-Inflammatory Cytokines in Keratinocytes	Cells. 2022 Aug 5;11(15):2429	Human	Cell culture supernatants
9	Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer	EMBO Mol Med. 2022 Jan 11;14(1):e14502	Human	Cell culture supernatants
10	SFTSV Infection Induced Interleukin-1β Secretion Through NLRP3 Inflammasome Activation	Front Immunol. 2021 Feb 23;12:595140	Human	cell supernatant
11	MiR-24-3p attenuates IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting BCL2L12	J Orthop Surg Res. 2021 Jun 11;16(1):371	Human	Cell culture supernatants
12	Immunomodulation‐Based Strategy for Improving Soft Tissue and Metal Implant Integration and Its Implications in the Development of Metal Soft Tissue Materials	Adv Funct Mater. 2020 March 20	Human	Cell culture supernatants
13	Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway	Front Oncol. 2020 Apr 21;10:624	Human	Cell culture medium
14	Tuning the surface immunomodulatory functions of polyetheretherketone for enhanced osseointegration	Biomaterials. 2020 Feb;230:119642	Human	Cell culture supernatants
15	MiR-297 alleviates LPS-induced A549 cell and mice lung injury via targeting cyclin dependent kinase 8	Int Immunopharmacol. 2020 Mar;80:106197	Human	Cell culture supernatants
16	Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China	Environ Int. 2020 Jun;139:105703	Human	Cell culture supernatants
17	Profiling and functional characterization of circulation LncRNAs that are associated with coronary atherosclerotic plaque stability	Am J Transl Res. 2019 Jun 15;11(6):3801-3815. eCollection 2019	Human	Cell culture supernatants
18	NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester	Cell Biochem Funct. 2019 Oct;37(7):464-473	Human	Cell culture supernatants
19	Optimized DNA electroporation for primary human T cell engineering	BMC Biotechnol. 2018 Jan 30;18(1):4	Human	Cell culture supernatants
20	Radiosensitization by CpG ODN7909 in an epidermoid laryngeal carcinoma Hep-2 cell line	J Int Med Res. 2017 Dec;45(6):2009-2022	Human	Cell culture supernatants
21	Abrasive Endoprosthetic Wear Particles Inhibit IFN-γ Secretion in Human Monocytes Via Upregulating TNF-α-Induced miR-29b	Inflammation. 2017 Feb;40(1):166-173	Human	Cell culture supernatants
twenty two	Linker-free covalent immobilization of heparin, SDF-1α, and CD47 on PTFE surface for antithrombogenicity, endothelialization and anti-inflammation	Biomaterials. 2017 Sep;140:201-211	Human	Cell culture supernatants
twenty three	Knockdown of p54nrb inhibits migration, invasion and TNF-α release of human acute monocytic leukemia THP1 cells	Oncol Rep. 2016 Jun;35(6):3742-8	Human	cell culture supernatants
24	Methylation of suppressor of cytokine signalling 1 gene promoter is associated with acute-on-chronic hepatitis B liver failure	J Viral Hepat. 2015 Mar;22(3):307-17	Human	plasma
25	Membrane cholesterol plays an important role in enteropathogen adhesion and the activation of innate immunity via flagellin-TLR5 signaling	Arch Microbiol. 2015 Aug;197(6):797-803	Human	cell culture supernatants
26	Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy	PLoS One. 2014 Jun 16;9(6):e99612	Human	cell culture supernatants
27	Prognoses of patients with acute-on-chronic hepatitis B liver failure are closely associated with altered SOCS1 mRNA expression and cytokine production following glucocorticoid treatment	Cell Mol Immunol. 2014 Jul;11(4):396-404	Human	plasma

VAL106
Number	Title	Journal	Species	Sample Types
1	Identifying cancer cell-secreted proteins that activate cancer-associated fibroblasts as prognostic factors for patients with pancreatic cancer	J Cell Mol Med.2022 Nov;26(22):5657-5669.	Human	Cell culture supernatants
2	Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells	Nucleic Acids Res. 2022 Jul 8;50(12):6601-6617	Human	cell culture supernatants
3	Hydrogel from acellular porcine adipose tissue promotes survival of adipose tissue transplantation	Biomed Mater. 2021 Apr 30;16(4)	Human	cell culture medium
4	Cyclic tensile forces enhance the angiogenic properties of HUVECs by promoting the activities of human periodontal ligament cells	J Periodontol. 2021 Jan;92(1):159-169	Human	cell culture supernatants
5	Implication of inflammatory cytokines in the aqueous humour for management of macular diseases	Acta Ophthalmol. 2020 May;98(3):e309-e315	Human	aqueous humour
6	Growth differentiation factor 9 inhibits vascular endothelial growth factor expression in human granulosa cells	Gynecol Endocrinol. 2020 Oct;36(10):907-911	Human	cell culture supernatants
7	The Caspase-3/PKCδ/Akt/VEGF-A Signaling Pathway Mediates Tumor Repopulation during Radiotherapy	Clin Cancer Res. 2019 Jun 15;25(12):3732-3743	Human	cell culture supernatants
8	Inflammatory cytokines in highly myopic eyes	Sci Rep. 2019 Mar 5;9(1):3517	Human	aqueous humor
9	PKC/NADPH oxidase are involved in the protective effect of pioglitazone in high homocysteine-induced paracrine dyfunction in endothelial progenitor cells	Am J Transl Res. 2017 Mar 15;9(3):1037-1048	Human	cell culture supernatants
10	Dying glioma cells establish a proangiogenic microenvironment through a caspase 3 dependent mechanism	Cancer Lett. 2017 Jan 28;385:12-20	Human	cell culture supernatants
11	Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis	Oncotarget. 2015 Oct 20;6(32):32353-67	Human	cell culture supernatants
12	12-Deoxyphorbol 13-palmitate inhibits the expression of VEGF and HIF-1α in MCF-7 cells by blocking the PI3K/Akt/mTOR signaling pathway	Oncol Rep. 2015 Oct;34(4):1755-60	Human	cell culture medium

VAL110
Number	Title	Journal	Species	Sample Types
1	Low level of ARID1A contributes to adaptive immune resistance and sensitizes triple-negative breast cancer to immune checkpoint inhibitors	Cancer Commun (Lond).2023 Sep;43(9):1003-1026.	Human	Cell culture supernatants
2	Histone Methyltransferase SETDB1 Promotes Immune Evasion in Colorectal Cancer via FOSB-Mediated Downregulation of MicroRNA-22 through BATF3/PD-L1 Pathway	J Immunol Res. 2022 Apr 20;2022:4012920	Human	cell culture supernatants
3	TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss	Cancer Cell Int. 2021 Apr 17;21(1):223	Human	cell culture supernatants
4	NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer	Nat Commun. 2020 Apr 3;11(1):1669	Human	cell culture supernatants
5	Caspase 3 in dying tumor cells mediates post-irradiation angiogenesis	J Exp Clin Cancer Res. 2018 Oct 29;37(1):261	Human	cell culture supernatants
6	Orai1 downregulation impairs lymphocyte function in type 2 diabetes mellitus	Biochem Biophys Res Commun. 2018 Jun 2;500(2):384-390	Human	cell culture supernatants
7	Optimized DNA electroporation for primary human T cell engineering	BMC Biotechnol. 2018 Jan 30;18(1):4	Human	cell culture supernatants

VAL112
Number	Title	Journal	Species	Sample Types
1	Creatine Kinase-MM/Proto-oncogene Tyrosine-Protein Kinase Receptor as a Sensitive Indicator for Duchenne Muscular Dystrophy Carriers	Mol Neurobiol. 2024 May 20.	Human	serum
2	NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester	Cell Biochem Funct. 2019 Oct;37(7):464-473	Human	cell culture supernatants
3	Characterization of the subsets of human NKT-like cells and the expression of Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion	J Reprod Immunol. 2015 Aug;110:81-8	Human	cell culture medium
4	Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy	PLoS One. 2014 Jun 16;9(6):e99612	Human	cell culture supernatants

VAL113
Number	Title	Journal	Species	Sample Types
1	Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy	Mol Ther Nucleic Acids.2022 Dec 12:31:88-104.	Human	cell culture supernatants
2	Profiling and functional characterization of circulation LncRNAs that are associated with coronary atherosclerotic plaque stability - PubMed (nih.gov)	Am J Transl Res. 2019 Jun 15;11(6):3801-3815.	Human	cell culture supernatants

VAL114
Number	Title	Journal	Species	Sample Types
1	Postmortem biochemical analysis of soluble ST2 in the pericardial fluid of patients with sudden cardiac death caused by ischemic heart disease: a pilot study	Forensic Sci Med Pathol.2023 Jul 14.	Human	pericardial fluid
2	IL-33 promotes the progression of nonrheumatic aortic valve stenosis via inducing differential phenotypic transition in valvular interstitial cells - PubMed (nih.gov)	J Cardiol. 2020 Feb;75(2):124-133	Human	plasma

VAL117
Number	Title	Journal	Species	Sample Types
1	Circulating PD-L1 is associated with T cell infiltration and predicts prognosis in patients with CRLM following hepatic resection - PubMed (nih.gov)	Cancer Immunol Immunother. 2022 Mar;71(3):661-674	Human	plasma, circulating exosomes

VAL121
Number	Title	Journal	Species	Sample Types
1	NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester	Cell Biochem Funct. 2019 Oct;37(7):464-473	Human	cell culture supernatants
2	Radiosensitization by CpG ODN7909 in an epidermoid laryngeal carcinoma Hep-2 cell line	J Int Med Res. 2017 Dec;45(6):2009-2022	Human	cell culture supernatants
3	Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy	PLoS One. 2014 Jun 16;9(6):e99612	Human	cell culture supernatants

VAL122
Number	Title	Journal	Species	Sample Types
1	Competitive binding of transcription factors underlies flexibility of T peripheral helper cells and T follicular helper cells in SLE	Rheumatology (Oxford). 2022 Nov 2;61(11):4547-4557	Human	serum

VAL123
Number	Title	Journal	Species	Sample Types
1	A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions	Bioact Mater. 2022 Feb 1;14:364-376	Mouse	cell culture supernatants
2	NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester	Cell Biochem Funct. 2019 Oct;37(7):464-473	Human	cell culture supernatants
3	Characterization of the subsets of human NKT-like cells and the expression of Th1/Th2 cytokines in patients with unexplained recurrent spontaneous abortion	J Reprod Immunol. 2015 Aug;110:81-8	Human	cell culture medium
4	Expression and functional characterization of NOD2 in decidual stromal cells isolated during the first trimester of pregnancy	PLoS One. 2014 Jun 16;9(6):e99612	Human	cell culture supernatants

VAL127
Number	Title	Journal	Species	Sample Types
1	Enhancement of the function of mesenchymal stem cells by using a GMP-grade three-dimensional hypoxic large-scale production system	Heliyon. 2024 May 18;10(10):e30968	Human	Cell culture supernatant
2	Metochalcone induces senescence-associated secretory phenotype via JAK2/STAT3 pathway in breast cancer	Oncol Res. 2024 Apr 23;32(5):943-953	Human	Cell culture supernatants
3	Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy - PubMed (nih.gov)	BMC Nephrol. 2022 Jan 11;23(1):25	Human	cell culture supernatants

VAL130
Number	Title	Journal	Species	Sample Types
1	Bispecific CS1-BCMA CAR-T cells are clinically active in relapsed or refractory multiple myeloma	Leukemia.2023 Oct 17.	Human	Bone marrow、Peripheral blood

VAL131
Number	Title	Journal	Species	Sample Types
1	Clinical Value of Serum Interleukin-18 in Neonatal Sepsis Diagnosis and Mortality Prediction	J Inflamm Res. 2022 Dec 30:15:6923-6930	Human	serum
2	MiR-24-3p attenuates IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting BCL2L12	J Orthop Surg Res. 2021 Jun 11;16(1):371	Human	cell culture supernatants
3	Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation	J Biol Chem. 2015 Jul 17;290(29):18018-18028	Human	cell culture supernatants
4	Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation	Int J Biochem Cell Biol. 2014 Dec;57:7-19	Human	cell culture supernatants

VAL134
Number	Title	Journal	Species	Sample Types
1	FSTL3 is highly expressed in adipose tissue of individuals with overweight or obesity and is associated with inflammation	Obesity (Silver Spring).2023 Jan;31(1):171-183.	Human	cell culture supernatants
2	NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester	Cell Biochem Funct. 2019 Oct;37(7):464-473	Human	cell culture supernatants

VAL137
Number	Title	Journal	Species	Sample Types
1	DNA of neutrophil extracellular traps promote NF-κB-dependent autoimmunity via cGAS/TLR9 in chronic obstructive pulmonary disease	Signal Transduct Target Ther. 2024 Jun 17;9(1):163	Human	Cell culture supernatant
2	Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis B	Virol J. 2024 Mar 21;21(1):72	Human	serum
3	Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis.	Cell Rep. 2023 Aug 29;42(8):112944	Human	Cell culture supernatants

VAL145
Number	Title	Journal	Species	Sample Types
1	KLF7 promotes colon adenocarcinoma progression through the PDGFB signaling pathway	Int J Biol Sci. 2024 Jan 1;20(1):387-402	Human	Cell culture supernatant

VAL146
Number	Title	Journal	Species	Sample Types
1	MiR-155-5p improves the insulin sensitivity of trophoblasts by targeting CEBPB in gestational diabetes mellitus	Placenta. 2024 Mar 25:148:1-11	Human	plasma

VAL601
Number	Title	Journal	Species	Sample Types
1	Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex	Research (Wash D C). 2024 Oct 8:7:0493	Mouse	cell and tissue homogenates
2	Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways	J Ethnopharmacol. 2025 Jan 10:336:118726.	Mouse	serum
3	Tryptanthrin suppresses multiple inflammasome activation to regulate NASH progression by targeting ASC protein	Phytomedicine. 2024 Aug:131:155758	Mouse	serum
4	Compact bone mesenchymal stem cells-derived paracrine mediators for cell-free therapy in sepsis	Biochem Biophys Res Commun. 2024 Oct 1:727:150313	Mouse	cell culture supernatants, tissue homogenates, serum
5	Tamarixetin ameliorates cerebral ischemia–reperfusion injury via suppressing nicotinamide adenine dinucleotide phosphate oxidase 2/nucleotide-binding oligomerization domain like receptor family pyrin domain-containing 3 inflammasome activation	Phytother Res. 2024 Aug;38(8):4286-4306.	Mouse	BV-2 cell
6	Unveiling the potent effect of vitamin D: harnessing Nrf2/HO-1 signaling pathways as molecular targets to alleviate urban particulate matter-induced asthma inflammation	BMC Pulm Med. 2024 Jan 25;24(1):55	Mouse	BALF，serum
7	SLC25A3 negatively regulates NLRP3 inflammasome activation by restricting the function of NLRP3	J Biol Chem. 2024 May;300(5):107233	Mouse	Cell culture supernatant
8	Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects.	iScience. 2024 Mar 20;27(4):109544.	Mouse	Cell culture supernatant，tissue homogenates
9	Macrophage ferroportin serves as a therapeutic target against bacteria-induced acute lung injury by promoting barrier restoration	iScience. 2022 Dec 1;25(12):105698	Mouse	BALF
10	Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase	Phytother Res.2023 Oct;37(10):4587-4606.	Mouse	serum
11	A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases	Eur J Pharmacol.2023 Sep 5:954:175840.	Mouse	serum
12	A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study	Acta Pharm Sin B.2023 Aug;13(8):3414-3424.	Mouse	plasma
13	Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice	J Sci Food Agric.2023 Aug 30;103(11):5529-5538.	Mouse	serum
14	The nano-windmill exerts superior anti-inflammatory effects via reducing choline uptake to inhibit macrophage activation	Cell Prolif.2023 Oct;56(10):e13470.	Mouse	cell culture supernatants
15	Neutralizing peripheral circulating IL1β slows the progression of ALS in a lentivirus-infected OPTNE478G mouse model	Animal Model Exp Med.2023 Feb;6(1):18-25.	Mouse	tissue homogenates
16	Enhanced activity of NLRP3 inflammasome and its proinflammatory effect in influenza A viral pneumonia		Mouse	serum, cell culture supernatants
17	Ozanimod-Dependent Activation of SIRT3/NF-κB/AIM2 Pathway Attenuates Secondary Injury After Intracerebral Hemorrhage	Mol Neurobiol.2023 Mar;60(3):1117-1131.	Mouse	cell culture supernatants
18	S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression	Cells.2022 Nov 12;11(22):3579.	Mouse	serum
19	Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages	Int Immunopharmacol.2022 Dec;113(Pt A):109404.	Mouse	serum
20	Translational selenium nanotherapeutics counter-acts multiple risk factors to improve surgery-induced cognitive impairment	Chemical Engineering Journal.Volume 441, 1 August 2022, 135984	Mouse	serum
21	Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice	J Agric Food Chem. 2022 May 11;70(18):5738-5747	Mouse	serum
22	High glutamate concentration reverses the inhibitory effect of microglial adenosine 2A receptor on NLRP3 inflammasome assembly and activation	Neurosci Lett. 2022 Jan 19;769:136431	Mouse	cell culture supernatants
23	FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis	Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101	Mouse	serum
24	Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein	Int Immunopharmacol. 2022 Oct;111:109148	Mouse	serum
25	Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer	EMBO Mol Med. 2022 Jan 11;14(1):e14502	Mouse	cell culture supernatants
26	Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β	Front Pharmacol. 2022 Jun 14;13:911157	Mouse	serum
27	Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice	Phytomedicine. 2022 Jul;101:154104	Mouse	plasma
28	Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice	Front Endocrinol (Lausanne). 2022 May 30;13:887238	Mouse	serum
29	Intelligent lesion blood-brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection	Acta Pharm Sin B. 2022 Apr;12(4):1987-1999	Mouse	serum, brain
30	Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury	Front Cell Neurosci. 2022 May 20;16:915969	Mouse	Tissue Lysates
31	Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction	J Ethnopharmacol. 2021 Nov 15;280:114474	Mouse	serum
32	SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	Cell Res. 2021 Aug;31(8):847-860	Mouse	serum,cell culture supernatantss
33	Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution	Adv Sci (Weinh). 2021 Feb 8;8(8):2003941	Mouse	cell culture supernatants
34	Caspase-11-Gasdermin D-Mediated Pyroptosis Is Involved in the Pathogenesis of Atherosclerosis	Front Pharmacol. 2021 Apr 26;12:657486	Mouse	cell culture supernatants
35	Adiponectin protects obesity-related glomerulopathy by inhibiting ROS/NF-κB/NLRP3 inflammation pathway	BMC Nephrol. 2021 Jun 10;22(1):218	Mouse	cell culture supernatants
36	Aggravated MRSA pneumonia secondary to influenza A virus infection is derived from decreased expression of IL-1β	J Med Virol. 2020 Jul 22;92(12):3047-3056	Mouse	cell culture supernatants,serum
37	Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1	Pathog Dis. 2020 Mar 1;78(2):ftaa016	Mouse	serum
38	Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation	Front Pharmacol. 2020 Oct 2;11:577319	Mouse	cell culture supernatants
39	4-Octyl itaconate inhibits aerobic glycolysis by targeting GAPDH to exert anti-inflammatory effects	Nat Commun. 2019 Nov 8;10(1):5091	Mouse	cell culture supernatants
40	MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway	Int J Mol Med. 2019 Feb;43(2):779-790	Mouse	cell culture supernatants
41	PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury	Mediators Inflamm. 2018 Oct 3;2018:6757368	Mouse	BALF
42	microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway	Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958	Mouse	cell culture supernatants
43	Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation	Neuron. 2018 Nov 7;100(3):551-563.e7	Mouse	cell culture supernatants
44	Clemastine Alleviates Depressive-Like Behavior Through Reversing the Imbalance of Microglia-Related Pro-inflammatory State in Mouse Hippocampus	Front Cell Neurosci. 2018 Nov 13;12:412	Mouse	serum
45	ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death	Front Immunol. 2018 Nov 14;9:2647	Mouse	cell culture supernatants,Tissue
46	Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages	Carbon.Volume 113, March 2017, Pages 176-191	Mouse	cell culture supernatants

VAL602
Number	Title	Journal	Species	Sample Types
1	Mycobacterium tuberculosis produces d-serine under hypoxia to limit CD8+ T cell-dependent immunity in mice	Nat Microbiol. 2024 Jul;9(7):1856-1872	Mouse	serum
2	Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model	Front Immunol. 2022 Apr 13;13:878832	Mouse	cell culture supernatants

VAL603
Number	Title	Journal	Species	Sample Types
1	Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation	J Ethnopharmacol.2024 Jan 30;319(Pt 2):117288.	Mouse	serum
2	A programmed surface on polyetheretherketone for sequentially dictating osteoimmunomodulation and bone regeneration to achieve ameliorative osseointegration under osteoporotic conditions	Bioact Mater. 2022 Feb 1;14:364-376	Mouse	cell culture supernatants

VAL604
Number	Title	Journal	Species	Sample Types
1	Nanomedicine-based co-delivery of a calcium channel inhibitor and a small molecule targeting CD47 for lung cancer immunotherapy	Nat Commun.2023 Nov 11;14(1):7306.	Mouse	cell culture supernatants
2	Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation	J Ethnopharmacol.2024 Jan 30;319(Pt 2):117288.	Mouse	serum
3	A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages	Int Immunopharmacol.2023 Nov;124(Pt B):110965.	Mouse	serum
4	Autologous olfactory mucosa mesenchymal stem cells treatment improves the neural network in chronic refractory epilepsy	Stem Cell Res Ther.2023 Sep 7;14(1):237.	Mouse	serum
5	Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase	Phytother Res.2023 Oct;37(10):4587-4606.	Mouse	serum
6	A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases	Eur J Pharmacol.2023 Sep 5:954:175840.	Mouse	serum
7	Parthenolide targets NLRP3 to treat inflammasome-related diseases	Int Immunopharmacol.2023 Jun:119:110229.	Mouse	serum, cell culture supernatants
8	Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice	J Sci Food Agric.2023 Aug 30;103(11):5529-5538.	Mouse	serum
9	Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease	Int J Mol Sci.2023 Mar 14;24(6):5549.	Mouse	serum
10	Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages	Int Immunopharmacol.2022 Dec;113(Pt A):109404.	Mouse	serum
11	Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice	J Agric Food Chem. 2022 May 11;70(18):5738-5747	Mouse	serum
12	Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation	Acta Pharm Sin B. 2022 Feb;12(2):907-923	Mouse	plasma
13	Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model	Front Immunol. 2022 Apr 13;13:878832	Mouse	cell culture supernatants
14	FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis	Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101	Mouse	serum
15	Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein	Int Immunopharmacol. 2022 Oct;111:109148	Mouse	serum
16	Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer	EMBO Mol Med. 2022 Jan 11;14(1):e14502	Mouse	cell culture supernatants
17	Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β	Front Pharmacol. 2022 Jun 14;13:911157	Mouse	serum
18	Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice	Phytomedicine. 2022 Jul;101:154104	Mouse	plasma
19	4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway	J Cell Mol Med. 2022 Mar;26(5):1515-1529	Mouse	cell culture supernatants
20	Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice	Front Endocrinol (Lausanne). 2022 May 30;13:887238	Mouse	serum
21	The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signalling pathway	Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211035251	Mouse	Tissue Homogenates
22	Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study	Phytomedicine. 2021 May;85:153390	Mouse	Tissue Homogenates
23	SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	Cell Res. 2021 Aug;31(8):847-860	Mouse	serum,cell culture supernatantss
24	Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution	Adv Sci (Weinh). 2021 Feb 8;8(8):2003941	Mouse	cell culture supernatants
25	Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction	J Ethnopharmacol. 2021 Nov 15;280:114474	Mouse	serum
26	A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge	Cell Rep. 2021 Dec 14;37(11):110112	Mouse	cell culture supernatants
27	Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation	Front Pharmacol. 2020 Oct 2;11:577319	Mouse	cell culture supernatants
28	Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor	Dev Cell. 2020 Apr 20;53(2):240-252.e7	Mouse	cell culture supernatants
29	Evaluation of His6-Metal Assemblies as a Drug Delivery Vehicle in the Treatment of Anterior Segment Disease Using a Corneal Inflammation Model	ACS Biomater Sci Eng. 2020 Jul 13;6(7):4012-4023	Mouse	cell culture supernatants
30	Dehydrocorydaline Accounts the Majority of Anti-Inflammatory Property of Corydalis Rhizoma in Cultured Macrophage	Evid Based Complement Alternat Med. 2020 Nov 17;2020:4181696	Mouse	cell culture supernatants
31	Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1	Pathog Dis. 2020 Mar 1;78(2):ftaa016	Mouse	serum
32	MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway	Int J Mol Med. 2019 Feb;43(2):779-790	Mouse	cell culture supernatants
33	Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury	J Neurotrauma. 2019 Mar 19;36(6):903-918	Mouse	cell culture supernatants
34	A thermo-sensitive, injectable and biodegradable in situ hydrogel as a potential formulation for uveitis treatment	J Mater Chem B.Issue 28, 2019	Mouse	cell culture supernatants
35	miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice	Transplant Proc. 2018 Dec;50(10):3831-3839	Mouse	serum, cell culture supernatants
36	microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway	Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958	Mouse	cell culture supernatants
37	Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice	Int J Biol Macromol. 2018 Oct 15;118(Pt A):365-374	Mouse	aorta and liver tissues
38	Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response	Cell. 2018 May 3;173(4):906-919.e13	Mouse	serum, cell culture supernatants
39	ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death	Front Immunol. 2018 Nov 14;9:2647	Mouse	cell culture supernatants,Tissue
40	Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages	Carbon.Volume 113, March 2017, Pages 176-191	Mouse	cell culture supernatants
41	Mir-24 regulates hepatocyte apoptosis via BIM during acute liver failure	Am J Transl Res. 2017 Nov 15;9(11):4925-4935	Mouse	serum
42	MicroRNA-182-5p Ameliorates Liver Ischemia-Reperfusion Injury by Suppressing Toll-Like Receptor 4	Transplant Proc. 2016 Oct;48(8):2809-2814	Mouse	serum, cell culture supernatants
43	mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency	Oncotarget. 2016 May 10;7(19):28435-47	Mouse	cell culture supernatants
44	miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6	PLoS One. 2014 Jul 2;9(7):e101530	Mouse	cell culture supernatants
45	Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells	J Ethnopharmacol. 2013 Jun 21;148(1):271-6	Mouse	cell culture supernatants

VAL604G
Number	Title	Journal	Species	Sample Types
1	Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex	Research (Wash D C). 2024 Oct 8:7:0493	Mouse	cell and tissue homogenates
2	Composition Characterization of Crossostephium chinense Leaf Essential Oil and Its Anti-Inflammatory Activity Mechanisms	Plants (Basel). 2024 Sep 6;13(17):2506	Mouse	cell culture supernatants
3	Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways.	Exp Biol Med (Maywood). 2024 Apr 22:249:10141	Mouse	serum
4	Polygonum perfoliatum L. ethanol extract ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin inflammation	J Ethnopharmacol.2024 Jan 30;319(Pt 2):117288.	Mouse	serum
5	Unveiling the potent effect of vitamin D: harnessing Nrf2/HO-1 signaling pathways as molecular targets to alleviate urban particulate matter-induced asthma inflammation	BMC Pulm Med. 2024 Jan 25;24(1):55	Mouse	BALF，serum
6	Nanomedicine-based co-delivery of a calcium channel inhibitor and a small molecule targeting CD47 for lung cancer immunotherapy	Nat Commun.2023 Nov 11;14(1):7306.	Mouse	cell culture supernatants
7	A natural sesquiterpene lactone isolinderalactone attenuates lipopolysaccharide-induced inflammatory response and acute lung injury through inhibition of NF-κB pathway and activation Nrf2 pathway in macrophages	Int Immunopharmacol.2023 Nov;124(Pt B):110965.	Mouse	serum
8	Scutellarein alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis by chelating iron and interacting with arachidonate 15-lipoxygenase	Phytother Res.2023 Oct;37(10):4587-4606.	Mouse	serum
9	Autologous olfactory mucosa mesenchymal stem cells treatment improves the neural network in chronic refractory epilepsy	Stem Cell Res Ther.2023 Sep 7;14(1):237.	Mouse	serum
10	A natural chalcone cardamonin inhibits necroptosis and ameliorates dextran sulfate sodium (DSS)-induced colitis by targeting RIPK1/3 kinases	Eur J Pharmacol.2023 Sep 5:954:175840.	Mouse	serum
11	Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice	J Sci Food Agric.2023 Aug 30;103(11):5529-5538.	Mouse	serum
12	Parthenolide targets NLRP3 to treat inflammasome-related diseases	Int Immunopharmacol.2023 Jun:119:110229.	Mouse	serum, cell culture supernatants
13	Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease	Int J Mol Sci.2023 Mar 14;24(6):5549.	Mouse	serum
14	MicroRNA-378 inhibits hepatocyte apoptosis during acute liver failure by targeting caspase-9 in mice	Gastroenterol Hepatol. 2023 Feb;46(2):124-134	Mouse	Serum
15	Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages	Int Immunopharmacol.2022 Dec;113(Pt A):109404.	Mouse	serum
16	Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein	Int Immunopharmacol. 2022 Oct;111:109148	Mouse	serum
17	FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis	Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101	Mouse	serum
18	Fragments of bombinakinin M exist in lipopolysaccharide-stimulated skin secretions of Bombina maxima and show lipopolysaccharide-neutralizing activity	J Immunol Methods. 2022 Oct:509:113343	Mouse	Cell culture supernatant
19	Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice	Phytomedicine. 2022 Jul;101:154104	Mouse	plasma
20	Anti-Inflammatory Effect of Acetone Extracts from Microalgae Chlorella sp. WZ13 on RAW264.7 Cells and TPA-induced Ear Edema in Mice	Front. Mar. Sci., 05 July 2022	Mouse	cells supernatant
21	Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β	Front Pharmacol. 2022 Jun 14;13:911157	Mouse	serum
22	Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice	J Agric Food Chem. 2022 May 11;70(18):5738-5747	Mouse	serum
23	Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice	Front Endocrinol (Lausanne). 2022 May 30;13:887238	Mouse	serum
24	Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model	Front Immunol. 2022 Apr 13;13:878832	Mouse	cell culture supernatants
25	4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway	J Cell Mol Med. 2022 Mar;26(5):1515-1529	Mouse	cell culture supernatants
26	Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation	Acta Pharm Sin B. 2022 Feb;12(2):907-923	Mouse	plasma
27	Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer	EMBO Mol Med. 2022 Jan 11;14(1):e14502	Mouse	cell culture supernatants
28	The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signalling pathway	Int J Immunopathol Pharmacol. 2021 Jan Dec;35:20587384211035251	Mouse	Tissue Homogenates
29	A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge	Cell Rep. 2021 Dec 14;37(11):110112	Mouse	cell culture supernatants
30	Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction	J Ethnopharmacol. 2021 Nov 15;280:114474	Mouse	serum
31	SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	Cell Res. 2021 Aug;31(8):847-860	Mouse	serum,cell culture supernatantss
32	Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study	Phytomedicine. 2021 May;85:153390	Mouse	Tissue Homogenates
33	Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution	Adv Sci (Weinh). 2021 Feb 8;8(8):2003941	Mouse	cell culture supernatants
34	Dehydrocorydaline Accounts the Majority of Anti-Inflammatory Property of Corydalis Rhizoma in Cultured Macrophage	Evid Based Complement Alternat Med. 2020 Nov 17;2020:4181696	Mouse	cell culture supernatants
35	Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation	Front Pharmacol. 2020 Oct 2;11:577319	Mouse	cell culture supernatants
36	Evaluation of His6-Metal Assemblies as a Drug Delivery Vehicle in the Treatment of Anterior Segment Disease Using a Corneal Inflammation Model	ACS Biomater Sci Eng. 2020 Jul 13;6(7):4012-4023	Mouse	cell culture supernatants
37	Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor	Dev Cell. 2020 Apr 20;53(2):240-252.e7	Mouse	cell culture supernatants
38	Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1	Pathog Dis. 2020 Mar 1;78(2):ftaa016	Mouse	serum
39	MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway	Int J Mol Med. 2019 Feb;43(2):779-790	Mouse	cell culture supernatants
40	Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury	J Neurotrauma. 2019 Mar 19;36(6):903-918	Mouse	cell culture supernatants
41	A thermo-sensitive, injectable and biodegradable in situ hydrogel as a potential formulation for uveitis treatment	J Mater Chem B.Issue 28, 2019	Mouse	cell culture supernatants
42	miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice	Transplant Proc. 2018 Dec;50(10):3831-3839	Mouse	serum, cell culture supernatants
43	microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway	Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958	Mouse	cell culture supernatants
44	Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice	Int J Biol Macromol. 2018 Oct 15;118(Pt A):365-374	Mouse	aorta and liver tissues
45	Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response	Cell. 2018 May 3;173(4):906-919.e13	Mouse	serum, cell culture supernatants
46	ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death	Front Immunol. 2018 Nov 14;9:2647	Mouse	cell culture supernatants,Tissue
47	Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages	Carbon.Volume 113, March 2017, Pages 176-191	Mouse	cell culture supernatants
48	Mir-24 regulates hepatocyte apoptosis via BIM during acute liver failure	Am J Transl Res. 2017 Nov 15;9(11):4925-4935	Mouse	serum
49	MicroRNA-182-5p Ameliorates Liver Ischemia-Reperfusion Injury by Suppressing Toll-Like Receptor 4	Transplant Proc. 2016 Oct;48(8):2809-2814	Mouse	serum, cell culture supernatants
50	mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency	Oncotarget. 2016 May 10;7(19):28435-47	Mouse	cell culture supernatants
51	miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6	PLoS One. 2014 Jul 2;9(7):e101530	Mouse	cell culture supernatants
52	Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells	J Ethnopharmacol. 2013 Jun 21;148(1):271-6	Mouse	cell culture supernatants

VAL605
Number	Title	Journal	Species	Sample Types
1	Human umbilical mesenchymal stem cell-derived exosomes alleviate bone destruction and regulate bone immunity via the aryl hydrocarbon receptor to treat rheumatoid arthritis	Int Immunopharmacol. 2024 Dec 25;143(Pt 2):113340	Mouse	serum
2	Fragments of bombinakinin M exist in lipopolysaccharide-stimulated skin secretions of Bombina maxima and show lipopolysaccharide-neutralizing activity	J Immunol Methods. 2022 Oct:509:113343	Mouse	Cell culture supernatant
3	4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway	J Cell Mol Med. 2022 Mar;26(5):1515-1529	Mouse	cell culture supernatants
4	Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study	Phytomedicine. 2021 May;85:153390	Mouse	Tissue Homogenates
5	SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	Cell Res. 2021 Aug;31(8):847-860	Mouse	serum,cell culture supernatants
6	Anti-inflammatory effect of low molecular weight fucoidan from Saccharina japonica on atherosclerosis in apoE-knockout mice	Int J Biol Macromol. 2018 Oct 15;118(Pt A):365-374	Mouse	aorta and liver tissues
7	ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death	Front Immunol. 2018 Nov 14;9:2647	Mouse	cell culture supernatants,Tissue
8	Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages	Carbon.Volume 113, March 2017, Pages 176-191	Mouse	cell culture supernatants

VAL606
Number	Title	Journal	Species	Sample Types
1	CLN-617 retains IL-2 and IL-12 in injected tumors to drive robust and systemic immune-mediated antitumor activity	Cancer Immunol Res. 2024 Aug 1;12(8):1022-1038	Mouse	serum,Tissue lysis

VAL607
Number	Title	Journal	Species	Sample Types
1	Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex	Research (Wash D C). 2024 Oct 8:7:0493	Mouse	cell and tissue homogenates
2	An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ	Mol Ther. 2022 Dec 7;30(12):3658-3676	Mouse	cell culture supernatants
3	Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model	Front Immunol. 2022 Apr 13;13:878832	Mouse	cell culture supernatants
4	The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signalling pathway	Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211035251	Mouse	Tissue Homogenates
5	Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study	Phytomedicine. 2021 May;85:153390	Mouse	Tissue Homogenates
6	SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	Cell Res. 2021 Aug;31(8):847-860	Mouse	serum,cell culture supernatants
7	Irgm1 knockout indirectly inhibits regeneration after skeletal muscle injury in mice	Int Immunopharmacol. 2020 Jul;84:106515	Mouse	serum,Tissue Homogenates
8	Evaluation of the protective immunity of a novel subunit fusion vaccine in a murine model of systemic MRSA infection	PLoS One. 2013 Dec 4;8(12):e81212	Mouse	cell culture supernatants

VAL608
Number	Title	Journal	Species	Sample Types
1	A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice	PLoS Genet. 2014 Oct 23;10(10):e1004589	Mouse	cell culture supernatants

VAL609
Number	Title	Journal	Species	Sample Types
1	Composition Characterization of Crossostephium chinense Leaf Essential Oil and Its Anti-Inflammatory Activity Mechanisms	Plants (Basel). 2024 Sep 6;13(17):2506	Mouse	cell culture supernatants
2	Melatonin Induces Analgesic Effects through MT2 Receptor-Mediated Neuroimmune Modulation in the Mice Anterior Cingulate Cortex	Research (Wash D C). 2024 Oct 8:7:0493	Mouse	cell and tissue homogenates
3	The zinc transporter Slc30a1 (ZnT1) in macrophages plays a protective role against attenuated Salmonella	Elife. 2024 Oct 30:13:e89509	Mouse	serum
4	Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways.	Exp Biol Med (Maywood). 2024 Apr 22:249:10141	Mouse	serum
5	MicroRNA-378 inhibits hepatocyte apoptosis during acute liver failure by targeting caspase-9 in mice	Gastroenterol Hepatol. 2023 Feb;46(2):124-134	Mouse	Serum
6	Macrophage ferroportin serves as a therapeutic target against bacteria-induced acute lung injury by promoting barrier restoration	iScience. 2022 Dec 1;25(12):105698	Mouse	BALF
7	Open-Ring Butenolides from a Marine-Derived Anti-Neuroinflammatory Fungus Aspergillus terreus Y10	Mar Drugs. 2018 Nov 2;16(11):428	Mouse	Cell culture supernatant
8	Fragments of bombinakinin M exist in lipopolysaccharide-stimulated skin secretions of Bombina maxima and show lipopolysaccharide-neutralizing activity	J Immunol Methods. 2022 Oct:509:113343	Mouse	Cell culture supernatant
9	Anti-Inflammatory Effect of Acetone Extracts from Microalgae Chlorella sp. WZ13 on RAW264.7 Cells and TPA-induced Ear Edema in Mice	Front. Mar. Sci., 05 July 2022	Mouse	cells supernatant
10	Programmed surface on poly(aryl-ether-ether-ketone) initiating immune mediation and fulfilling bone regeneration sequentially	Innovation (Camb). 2021 Aug 5;2(3):100148	Mouse	Cell culture supernatant
11	Parthenolide targets NLRP3 to treat inflammasome-related diseases	Int Immunopharmacol.2023 Jun:119:110229.	Mouse	serum, cell culture supernatants
12	Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice	J Sci Food Agric.2023 Aug 30;103(11):5529-5538.	Mouse	serum
13	Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease	Int J Mol Sci.2023 Mar 14;24(6):5549.	Mouse	serum
14	Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair	Reprod Sci.2023 Jun;30(6):1979-1993.	Mouse	plasma
15	Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages	Int Immunopharmacol.2022 Dec;113(Pt A):109404.	Mouse	serum
16	Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood–brain barrier disruption in murine ischemic stroke models	Acta Biomater.2022 Dec:154:424-442.	Mouse	cell culture supernatants
17	Combined delivery of small molecule and protein drugs as synergistic therapeutics for treating corneal neovascularization by a one-pot coassembly strategy	Mater Today Bio.2022 Oct 8:17:100456.	Mouse	Cell culture supernatants
18	Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice	J Agric Food Chem. 2022 May 11;70(18):5738-5747	Mouse	serum
19	Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation	Acta Pharm Sin B. 2022 Feb;12(2):907-923	Mouse	plasma
20	Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model	Front Immunol. 2022 Apr 13;13:878832	Mouse	cell culture supernatants
21	FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis	Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101	Mouse	serum
22	Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein	Int Immunopharmacol. 2022 Oct;111:109148	Mouse	serum
23	Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation	J. Med. Chem. 2022, 65, 1, 103–119	Mouse	serum
24	Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer	EMBO Mol Med. 2022 Jan 11;14(1):e14502	Mouse	cell culture supernatants
25	Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β	Front Pharmacol. 2022 Jun 14;13:911157	Mouse	serum
26	Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice	Phytomedicine. 2022 Jul;101:154104	Mouse	plasma
27	Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice	Front Endocrinol (Lausanne). 2022 May 30;13:887238	Mouse	serum
28	Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury	Front Cell Neurosci. 2022 May 20;16:915969	Mouse	Tissue Lysates
29	4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway	J Cell Mol Med. 2022 Mar;26(5):1515-1529	Mouse	cell culture supernatants
30	The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signalling pathway	Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211035251	Mouse	Tissue Homogenates
31	Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study	Phytomedicine. 2021 May;85:153390	Mouse	Tissue Homogenates
32	SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target	Cell Res. 2021 Aug;31(8):847-860	Mouse	serum,cell culture supernatants
33	Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution	Adv Sci (Weinh). 2021 Feb 8;8(8):2003941	Mouse	cell culture supernatants
34	Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction	J Ethnopharmacol. 2021 Nov 15;280:114474	Mouse	serum
35	A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge	Cell Rep. 2021 Dec 14;37(11):110112	Mouse	cell culture supernatants
36	A more defective substrate leads to a less defective passive layer: Enhancing the mechanical strength, corrosion resistance and anti-inflammatory response of the low-modulus Ti-45Nb alloy by grain refinement	Acta Biomater. 2021 May;126:524-536	Mouse	cell culture supernatants
37	Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes	J Neuroinflammation. 2020 Feb 5;17(1):50	Mouse	cell culture medium
38	Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation	Front Pharmacol. 2020 Oct 2;11:577319	Mouse	cell culture supernatants
39	Evaluation of His6-Metal Assemblies as a Drug Delivery Vehicle in the Treatment of Anterior Segment Disease Using a Corneal Inflammation Model	ACS Biomater Sci Eng. 2020 Jul 13;6(7):4012-4023	Mouse	cell culture supernatants
40	Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1	Pathog Dis. 2020 Mar 1;78(2):ftaa016	Mouse	serum
41	Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury	J Neurotrauma. 2019 Mar 19;36(6):903-918	Mouse	cell culture supernatants
42	MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway	Int J Mol Med. 2019 Feb;43(2):779-790	Mouse	cell culture supernatants
43	ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death	Front Immunol. 2018 Nov 14;9:2647	Mouse	cell culture supernatants,Tissue
44	Resolvin D1 attenuates imiquimod-induced mice psoriasiform dermatitis through MAPKs and NF-κB pathways	J Dermatol Sci. 2018 Feb;89(2):127-135	Mouse	serum
45	miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice	Transplant Proc. 2018 Dec;50(10):3831-3839	Mouse	serum, cell culture supernatants
46	PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury	Mediators Inflamm. 2018 Oct 3;2018:6757368	Mouse	BALF
47	microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway	Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958	Mouse	cell culture supernatants
48	Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages	Carbon.Volume 113, March 2017, Pages 176-191	Mouse	cell culture supernatants
49	Mir-24 regulates hepatocyte apoptosis via BIM during acute liver failure	Am J Transl Res. 2017 Nov 15;9(11):4925-4935	Mouse	serum
50	MicroRNA-182-5p Ameliorates Liver Ischemia-Reperfusion Injury by Suppressing Toll-Like Receptor 4	Transplant Proc. 2016 Oct;48(8):2809-2814	Mouse	serum, cell culture supernatants
51	CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment	Sci Rep. 2015 Nov 3;5:15948	Mouse	Serum
52	miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6	PLoS One. 2014 Jul 2;9(7):e101530	Mouse	cell culture supernatants
53	Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells	J Ethnopharmacol. 2013 Jun 21;148(1):271-6	Mouse	cell culture supernatants

VAL610
Number	Title	Journal	Species	Sample Types
1	Composition Characterization of Crossostephium chinense Leaf Essential Oil and Its Anti-Inflammatory Activity Mechanisms	Plants (Basel). 2024 Sep 6;13(17):2506	Mouse	cell culture supernatants
2	Evaluation of the protective immunity of a novel subunit fusion vaccine in a murine model of systemic MRSA infection	PLoS One. 2013 Dec 4;8(12):e81212	Mouse	cell culture supernatants

VAL611
Number	Title	Journal	Species	Sample Types
1	Human umbilical mesenchymal stem cell-derived exosomes alleviate bone destruction and regulate bone immunity via the aryl hydrocarbon receptor to treat rheumatoid arthritis	Int Immunopharmacol. 2024 Dec 25;143(Pt 2):113340	Mouse	serum
2	Programmed surface on poly(aryl-ether-ether-ketone) initiating immune mediation and fulfilling bone regeneration sequentially	Innovation (Camb). 2021 Aug 5;2(3):100148	Mouse	Cell culture supernatant
3	Bidirectional regulation between tumor cell-intrinsic PD-L1 and TGF-β1 in epithelial-to-mesenchymal transition in melanoma	Transl Cancer Res.2022 Oct;11(10):3698-3710.	Mouse	Cell culture supernatants;Tissue Homogenates
4	Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression	Cell Death Dis. 2022 Jul 19;13(7):624.	Mouse	serum
5	Immune dysfunction induced by 2,6-dichloro-1,4-benzoquinone, an emerging water disinfection byproduct, due to the defects of host-microbiome interactions	Chemosphere. 2022 May;294:133777	Mouse	serum
6	Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury	Front Cell Neurosci. 2022 May 20;16:915969	Mouse	Tissue Lysates
7	Targeted exosomes for co-delivery of siFGL1 and siTGF-β1 trigger combined cancer immunotherapy by remodeling immunosuppressive tumor microenvironment	Chemical Engineering Journal.Volume 421, Part 1, 1 October 2021, 129774	Mouse	cell culture supernatants
8	A more defective substrate leads to a less defective passive layer: Enhancing the mechanical strength, corrosion resistance and anti-inflammatory response of the low-modulus Ti-45Nb alloy by grain refinement	Acta Biomater. 2021 May;126:524-536	Mouse	Cell culture supernatants

VAL612
Number	Title	Journal	Species	Sample Types
1	Npc1 deficiency impairs microglia function via TREM2-mTOR signaling in Niemann-Pick disease type C	Biochim Biophys Acta Mol Basis Dis. 2024 Dec;1870(8):167478	Mouse	Serum
2	TIPE1 limits virus replication by disrupting PKM2/ HIF-1α/ glycolysis feedback loop	Free Radic Biol Med. 2024 Aug 20:221:52-63	Mouse	Cell culture supernatants, serum
3	Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages	Cell Rep. 2022 Nov 29;41(9):111738	Mouse	Tissue Homogenates,Cell culture supernatants,Serum
4	A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge	Cell Rep. 2021 Dec 14;37(11):110112	Mouse	Cell culture supernatants

VAL619
Number	Title	Journal	Species	Sample Types
1	Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways	J Ethnopharmacol. 2025 Jan 10:336:118726.	Mouse	serum
2	Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury	J Neurotrauma. 2019 Mar 19;36(6):903-918	Mouse	Cell culture supernatants

VAL626
Number	Title	Journal	Species	Sample Types
1	Evaluation of the protective immunity of a novel subunit fusion vaccine in a murine model of systemic MRSA infection	PLoS One. 2013 Dec 4;8(12):e81212	Mouse	Cell culture supernatants

VAL901
Number	Title	Journal	Species	Sample Types
1	mTORC1-mediated downregulation of COX2 restrains tumor growth caused by TSC2 deficiency	Oncotarget. 2016 May 10;7(19):28435-47	Mouse	Cell culture supernatants
2	Triptolide attenuates acute small-for-size liver graft injury in rats by inhibition of Toll-like receptor 4	Transplant Proc. 2014 Dec;46(10):3303-8	Rat	serum

VAL902
Number	Title	Journal	Species	Sample Types
1	Low bone turnover is associated with advanced glycation end-products, oxidative stress, and inflammation induced by type 2 diabetes mellitus	FASEB J. 2024 Aug 15;38(15):e23871	Rat	serum, cell supernatant
2	Probiotic strains improve high-fat diet-induced hypercholesterolemia through modulating gut microbiota in ways different from atorvastatin	Food Funct. 2019 Sep 18;10(9):6098-6109	Rat	Serum
3	Triptolide attenuates acute small-for-size liver graft injury in rats by inhibition of Toll-like receptor 4	Transplant Proc. 2014 Dec;46(10):3303-8	Rat	serum

VAL903
Number	Title	Journal	Species	Sample Types
1	Probiotic strains improve high-fat diet-induced hypercholesterolemia through modulating gut microbiota in ways different from atorvastatin	Food Funct. 2019 Sep 18;10(9):6098-6109	Rat	Serum