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GSK J5

Catalog #: 4689
2 Citations Datasheet / COA / SDS
Newer Version Available: 6935
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Discontinued Product

4689 has been discontinued and is replaced by 6935.

GSK J5 | CAS No. 1394854-51-3 | Histone Demethylase Inhibitors
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Description: Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable

Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester

Purity: ≥98%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Inactive isomer of GSK J4; also cell permeable ester derivative of the inactive control, GSK J2.

Active Analog also available.

Technical Data

M.Wt:
417.5
Formula:
C24H27N5O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
1394854-51-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details of GSK J5, a cell permeable inactive isomer of GSK J1, please visit the GSK J1 probe summary on the SGC website.
Other Product-Specific Information:

Product Datasheets

Reconstitution Calculator
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Reconstitution Calculator

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Citations for GSK J5

The citations listed below are publications that use Tocris products. Selected citations for GSK J5 include:

2 Citations: Showing 1 - 2

  1. Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks.
    Authors: Bayo Et al.
    Cell Rep  2018;25:1040
  2. Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.
    Authors: Carey Et al.
    Int J Nanomedicine  2015;518:413

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