Is ACE-1 the same as ACE?

Name: Human ACE/CD143 Antibody
Brand: R&D Systems
SKU: MAB9291
Price: 549 USD

Yes. ACE-1 is used as an alternative name, but not as commonly as ACE and CD143.

Human ACE/CD143 Antibody

Catalog #: MAB9291 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB9291
MAB9291-SP

All ACE/CD143 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human ACE/CD143 Antibody Summary

Species Reactivity

Human

Specificity

Detects recombinant human (rh)ACE in direct ELISAs and Western blots. Does not cross-react with rhACE-2 or rhNeprilysin.

Source

Monoclonal Mouse IgG₁ Clone # 171409

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Mouse myeloma cell line NS0-derived recombinant human ACE
Leu30-Leu1261
Accession # P12821.1

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human ACE/CD143 Somatic Form (Catalog # 929-ZN)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ACE/CD143

ACE, also known as kininase II and CD143 antigen, is a dipeptidyl carboxyl peptidase that contains zinc. It plays an important role in blood pressure regulation and electrolyte balance by hydrolyzing angiotensin I into angiotensin II, a potent vasopressor and aldosterone-stimulating peptide.

Long Name

Angiotensin I Converting Enzyme

Entrez Gene IDs

1636 (Human); 11421 (Mouse)

Alternate Names

ACE; ACE1angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; carboxycathepsin; CD143 antigen; CD143; DCP; DCP1; DCP1angiotensin-converting enzyme; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase I; EC 3.2.1.-; EC 3.4.15.1; Kininase II; MGC26566; MVCD3; peptidase P; testicular ECA