Human Active MMP-13 Fluorokine E Kit
Human Active MMP-13 Fluorokine E Kit Summary
Specifications
Product Datasheets
Background: MMP-13
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
Citations for Human Active MMP-13 Fluorokine E Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
3
Citations: Showing 1 - 3
Filter your results:
Filter by:
-
Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease
Authors: J Fu, S Li, R Feng, H Ma, F Sabeh, GD Roodman, J Wang, S Robinson, XE Guo, T Lund, D Normolle, MY Mapara, SJ Weiss, S Lentzsch
J Clin Invest, 2016-04-04;0(0):. 2016-04-04
-
Effects of high mobility group box protein-1, interleukin-1beta, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures.
Authors: Ley C, Svala E, Nilton A, Lindahl A, Eloranta ML, Ekman S, Skioldebrand E
Connect. Tissue Res., 2010-11-30;52(4):290-300. 2010-11-30
-
CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion.
Authors: Singh S, Singh UP, Grizzle WE, Lillard JW
Lab. Invest., 2004-12-01;84(12):1666-76. 2004-12-01
FAQs
No product specific FAQs exist for this product, however you may
View all Activity Assay FAQsReviews for Human Active MMP-13 Fluorokine E Kit
Average Rating: 5 (Based on 1 Review)
Have you used Human Active MMP-13 Fluorokine E Kit?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by:
