Home / CRACC/SLAMF7 / Human CRACC/SLAMF7 APC-conjugated Antibody

Human CRACC/SLAMF7 APC-conjugated Antibody

Catalog #: FAB1906A
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB1906A
Detection of CRACC/SLAMF7 in Human PBMCs by Flow Cytometry.
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Human CRACC/SLAMF7 APC-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human CRACC/SLAMF7 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human NTB-AR is observed.
Source
Monoclonal Mouse IgG2A Clone # 235614
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CRACC/SLAMF7
Lys27-Ser225
Accession # Q9NQ25
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Allophycocyanin (Excitation= 620-650 nm, Emission= 660-670 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of CRACC/SLAMF7 antibody in Human PBMCs antibody by Flow Cytometry. View Larger

Detection of CRACC/SLAMF7 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) gated on CD3-cells were stained with Mouse Anti-Human NCAM-1/CD56 PE-conjugated Monoclonal Antibody (Catalog # FAB2408P) and either (A) Mouse Anti-Human CRACC/SLAMF7 APC-conjugated Monoclonal Antibody (Catalog # FAB1906A) or (B) Mouse IgG2AAllophycocyanin Isotype Control (Catalog # IC003A). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: CRACC/SLAMF7

CRACC, also known as CSI (CD2 subset I), is a type I transmembrane protein belonging to the CD2 subset of the Ig superfamily. CRACC is expressed on most NK cells and subsets of CD8+ cells, CD4+ cells and B cells. CRACC may play a role in the activation and effector function of T cells and NK cells.

Entrez Gene IDs
57823 (Human); 75345 (Mouse); 102133710 (Cynomolgus Monkey)
Alternate Names
19A; CD2 subset 1; CD2-like receptor activating cytotoxic cells; CD319 antigen; CD319; CRACC; CRACCCD2-like receptor-activating cytotoxic cells; CS119A24 protein; Membrane protein FOAP-12; novel LY9 (lymphocyte antigen 9) like protein; Novel Ly9; Protein 19A; SLAM family member 7; SLAMF7

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Citation for Human CRACC/SLAMF7 APC-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Flow cytometry-based characterization of underlying clonal B and plasma cells in patients with light chain amyloidosis
    Authors: K Lisenko, SO Schönland, A Jauch, M Andrulis, C Röcken, AD Ho, H Goldschmid, U Hegenbart, M Hundemer
    Cancer Med, 2016-04-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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