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Human CTRP1/C1qTNF1 Antibody

Catalog #: AF3145
3 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF3145
AF3145-SP
Product Details
Citations (3)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human CTRP1/C1qTNF1 Antibody Summary

Species Reactivity
Human
Specificity
Detects human CTRP1/C1qTNF1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) CTRP4 and rhCTRP5 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CTRP1/C1qTNF1
Arg26-Pro281
Accession # Q9BXJ1
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human CTRP1/C1qTNF1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CTRP1/C1qTNF1

C1qTNF1, also known as CTRP1, is a secreted protein that belongs to the highly conserved family of Acrp30/Adiponectin paralogs known as C1q and TNF-related protein family. All family members share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a
C‑terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. Human and mouse C1qTNF1 share 78% amino acid sequence identity.

Long Name
C1q And Tumor Necrosis Factor Related Protein 1
Entrez Gene IDs
114897 (Human); 56745 (Mouse); 303701 (Rat)
Alternate Names
C1q and tumor necrosis factor related protein 1; C1qTNF1; CTRP1; CTRP1G protein-coupled receptor-interacting protein; FLJ90694; G protein coupled receptor interacting protein; GIPcomplement C1q tumor necrosis factor-related protein 1; ZSIG37

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Citations for Human CTRP1/C1qTNF1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. A novel adipokine C1q/TNF-related protein 1 (CTRP1) regulates chondrocyte proliferation and maturation through the ERK1/2 signaling pathway.
    Authors: Akiyama H, Otani M, Sato S, Toyosawa S, Furukawa S, Wakisaka S, Maeda T
    Mol Cell Endocrinol, 2013-01-21;369(1):63-71.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  2. Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions.
    Authors: Wong GW, Krawczyk SA, Kitidis-Mitrokostas C, Revett T, Gimeno R, Lodish HF
    Biochem. J., 2008-12-01;416(2):161-77.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Western Blot
  3. A novel adipokine CTRP1 stimulates aldosterone production.
    Authors: Jeon JH, Kim KY, Kim JH, Baek A, Cho H, Lee YH, Kim JW, Kim D, Han SH, Lim JS, Kim KI, Yoon do Y, Kim SH, Oh GT, Kim E, Yang Y
    FASEB J., 2008-01-02;22(5):1502-11.
    Species: Human
    Sample Types: Serum
    Applications: Western Blot

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