Human IL-8/CXCL8 DuoSet ELISA Summary
* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.
This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human CXCL8/IL-8. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.
Product Features
- Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
- Development protocols are provided to guide further assay optimization
- Assay can be customized to your specific needs
- Economical alternative to complete kits
Kit Content
- Capture Antibody
- Detection Antibody
- Recombinant Standard
- Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)
Other Reagents Required
DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.
The components listed above may be purchased separately:
PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered
Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4
Block Buffer: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered
Reagent Diluent: 0.1% BSA, 0.05% Tween 20 in Tris-buffered Saline (20 mM Trizma base, 150 mM NaCI) pH 7.2-7.4, 0.2 μm filtered
Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)
Stop Solution: 2 N H2SO4 (Catalog # DY994)
Microplates: R&D Systems (Catalog # DY990)
Plate Sealers: ELISA Plate Sealers (Catalog # DY992)
Scientific Data
Product Datasheets
Preparation and Storage
Background: IL-8/CXCL8
Interleukin-8 (IL-8), also known as IL-8, GCP-1, and NAP-1, is a heparin-binding 8-9 kDa member of the alpha, or CXC family of chemokines. There are at least 15 human CXC family members that all adopt a three beta -sheet/one alpha -helix structure. Most CXC chemokines show an N-terminal Glu-Leu-Arg (ELR) tripeptide motif. IL-8 circulates as a monomer, homodimer, and heterodimer with CXCL4/PF4. The monomer is considered the most bio-active, while the heterodimer can potentiate PF4 activity. IL-8 oligomerization is modulated by its interactions with matrix and cell surface glycosaminoglycans (GAGs). Mature human IL-8 shares 65-69% amino acid (aa) identity with canine, feline, and porcine IL-8. There is no IL-8 gene counterpart in rodent.
Assay Procedure
GENERAL ELISA PROTOCOL
Plate Preparation
- Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
- Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
- Block plates by adding 300 μL of Block Buffer to each well. Incubate at room temperature for a minimum of 1 hour.
- Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.
Assay Procedure
- Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
- Repeat the aspiration/wash as in step 2 of Plate Preparation.
- Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Repeat the aspiration/wash as in step 2.
- Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
- Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
- Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.
Citations for Human IL-8/CXCL8 DuoSet ELISA
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Dimethyl Fumarate-Loaded Gellan Gum Hydrogels Can Reduce In Vitro Chemokine Expression in Oral Cells
Authors: Wang, L;Dos Santos Sanches, N;Panahipour, L;Imani, A;Yao, Y;Zhang, Y;Li, L;Gruber, R;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa isolates from cystic fibrosis patients
Authors: Pedersen, BH;Simões, FB;Pogrebnyakov, I;Welch, M;Johansen, HK;Molin, S;La Rosa, R;
PLoS biology
Species: Human
Sample Types: Cell Culture Supernates
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Exploring the potency of polyphenol-rich blend from Lonicera caerulea var. Kamtschatica sevast., Aronia melanocarpa, and Echinacea purpurea: Promising anti-inflammatory, antioxidant, and antiviral properties
Authors: Zima, K;Khaidakov, B;Sochocka, M;Ochnik, M;Lemke, K;Kowalczyk, P;
Heliyon
Species: Human
Sample Types: Cell Culture Supernates
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Endoplasmic Reticulum Stress Differently Modulates the Release of IL-6 and IL-8 Cytokines in Human Glial Cells
Authors: Soko?owska, P;Wiktorowska-Owczarek, A;Tambor, J;Gawlak-Socka, S;Kowalczyk, E;Jó?wiak-B?benista, M;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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The assembly of neutrophil inflammasomes during COVID-19 is mediated by type I interferons
Authors: Cabrera, LE;Jokiranta, ST;Mäki, S;Miettinen, S;Kant, R;Kareinen, L;Sironen, T;Pietilä, JP;Kantele, A;Kekäläinen, E;Lindgren, H;Mattila, P;Kipar, A;Vapalahti, O;Strandin, T;
PLoS pathogens
Species: Human
Sample Types: Cell Culture Supernates
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Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein
Authors: Caohuy, H;Eidelman, O;Chen, T;Mungunsukh, O;Yang, Q;Walton, NI;Pollard, BS;Khanal, S;Hentschel, S;Florez, C;Herbert, AS;Pollard, HB;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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Effect of progestin-based contraceptives on HIV-associated vaginal immune biomarkers and microbiome in adolescent girls
Authors: Nasr, MA;Aldous, A;Daniels, J;Joy, C;Capozzi, E;Yang, M;Moriarty, P;Emmanuel-Baker, V;Malcolm, S;Green, SJ;Gomez-Lobo, V;Ghosh, M;
PloS one
Species: Human
Sample Types: Vaginal Swab
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Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing
Authors: Reedy, JL;Jensen, KN;Crossen, AJ;Basham, KJ;Ward, RA;Reardon, CM;Brown Harding, H;Hepworth, OW;Simaku, P;Kwaku, GN;Tone, K;Willment, JA;Reid, DM;Stappers, MHT;Brown, GD;Rajagopal, J;Vyas, JM;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
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Neutrophil extracellular traps promote immunopathogenesis of virus-induced COPD exacerbations
Authors: Katsoulis, O;Toussaint, M;Jackson, MM;Mallia, P;Footitt, J;Mincham, KT;Meyer, GFM;Kebadze, T;Gilmour, A;Long, M;Aswani, AD;Snelgrove, RJ;Johnston, SL;Chalmers, JD;Singanayagam, A;
Nature communications
Species: Human
Sample Types: Sputum
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Intestinal Epithelial Co-Culture Sensitivity to Pro-Inflammatory Stimuli and Polyphenols Is Medium-Independent
Authors: Haddad, MJ;Zuluaga-Arango, J;Mathieu, H;Barbezier, N;Anton, PM;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Taxonomic and phenotypic analysis of bifidobacteria isolated from IBD patients as potential probiotic strains
Authors: Bosselaar, S;Dhelin, L;Dautel, E;Titecat, M;Duthoy, S;Stelmaszczyk, M;Delory, N;De Sousa Violante, M;Machuron, F;Ait-Abderrahim, H;Desreumaux, P;Foligné, B;Monnet, C;
BMC microbiology
Species: Human
Sample Types: Cell Culture Supernates
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Effect of Isoscopoletin on Cytokine Expression in HaCaT Keratinocytes and RBL-2H3 Basophils: Preliminary Study
Authors: Seo, DY;Park, JW;Kim, SH;Oh, SR;Han, SB;Kwon, OK;Ahn, KS;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling
Authors: Halasz, H;Malekos, E;Covarrubias, S;Yitiz, S;Montano, C;Sudek, L;Katzman, S;Liu, SJ;Horlbeck, MA;Namvar, L;Weissman, JS;Carpenter, S;
Proceedings of the National Academy of Sciences of the United States of America
Species: Human
Sample Types: Cell Culture Supernates
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Lipoarabinomannan modification as a source of phenotypic heterogeneity in host-adapted Mycobacterium abscessus isolates
Authors: De, K;Belardinelli, JM;Pandurangan, AP;Ehianeta, T;Lian, E;Pal?eková, Z;Lam, H;Gonzalez-Juarrero, M;Bryant, JM;Blundell, TL;Parkhill, J;Floto, RA;Lowary, TL;Wheat, WH;Jackson, M;
Proceedings of the National Academy of Sciences of the United States of America
Species: Human
Sample Types: Cell Culture Supernates
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Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes
Authors: Roos, J;Zinngrebe, J;Huber-Lang, M;Lupu, L;Schmidt, MA;Strobel, H;Westhoff, MA;Stifel, U;Gebhard, F;Wabitsch, M;Mollnes, TE;Debatin, KM;Halbgebauer, R;Fischer-Posovszky, P;
Cell death & disease
Species: Human
Sample Types: Cell Culture Supernates
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Empowering Naringin's Anti-Inflammatory Effects through Nanoencapsulation
Authors: Marinho, A;Seabra, CL;Lima, SAC;Lobo-da-Cunha, A;Reis, S;Nunes, C;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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The proteome of bacterial membrane vesicles in Escherichia coli-a time course comparison study in two different media
Authors: Yu, MSC;Chiang, DM;Reithmair, M;Meidert, A;Brandes, F;Schelling, G;Ludwig, C;Meng, C;Kirchner, B;Zenner, C;Muller, L;Pfaffl, MW;
Frontiers in microbiology
Species: Human
Sample Types: Cell Culture Supernates
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Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes
Authors: Zhang, Y;Bharathi, V;Dokoshi, T;de Anda, J;Ursery, LT;Kulkarni, NN;Nakamura, Y;Chen, J;Luo, EWC;Wang, L;Xu, H;Coady, A;Zurich, R;Lee, MW;Matsui, T;Lee, H;Chan, LC;Schepmoes, AA;Lipton, MS;Zhao, R;Adkins, JN;Clair, GC;Thurlow, LR;Schisler, JC;Wolfgang, MC;Hagan, RS;Yeaman, MR;Weiss, TM;Chen, X;Li, MMH;Nizet, V;Antoniak, S;Mackman, N;Gallo, RL;Wong, GCL;
Proceedings of the National Academy of Sciences of the United States of America
Species: Human
Sample Types: Cell Culture Supernates
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P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis
Authors: Li, Z;Barnaby, R;Nymon, A;Roche, C;Koeppen, K;Ashare, A;Hogan, DA;Gerber, SA;Taatjes, DJ;Hampton, TH;Stanton, BA;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: BALF
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Efficacy of Lactiplantibacillus plantarum PBS067, Bifidobacterium animalis subsp. lactis BL050, and Lacticaseibacillus rhamnosus LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial
Authors: Vicariotto, F;Malfa, P;Viciani, E;Dell'Atti, F;Squarzanti, DF;Marcante, A;Castagnetti, A;Ponchia, R;Governini, L;De Leo, V;
Nutrients
Species: Human
Sample Types: Vaginal Swab
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The clarithromycin-binding proteins NIPSNAP1 and 2 regulate cytokine production through mitochondrial quality control
Authors: Yamamoto, S;Ogasawara, N;Mitsuhashi, Y;Takano, K;Yokota, SI;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air-liquid interface
Authors: Upadhyay, S;Rahman, M;Rinaldi, S;Koelmel, J;Lin, EZ;Mahesh, PA;Beckers, J;Johanson, G;Pollitt, KJG;Palmberg, L;Irmler, M;Ganguly, K;
Respiratory research
Species: Human
Sample Types: Cell Culture Supernates
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ADS024, a single-strain live biotherapeutic product of Bacillus velezensis alleviates dextran sulfate-mediated colitis in mice, protects human colonic epithelial cells against apoptosis, and maintains epithelial barrier function
Authors: Irwin, S;Chupina Estrada, A;Nelson, B;Bullock, A;Limketkai, B;Ho, W;Acton, S;Chesnel, L;Koon, HW;
Frontiers in microbiology
Species: Human
Sample Types: Cell Culture Supernates
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Highly secreted tryptophanyl tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis
Authors: Kim, YT;Huh, JW;Choi, YH;Yoon, HK;Nguyen, TT;Chun, E;Jeong, G;Park, S;Ahn, S;Lee, WK;Noh, YW;Lee, KS;Ahn, HS;Lee, C;Lee, SM;Kim, KS;Suh, GJ;Jeon, K;Kim, S;Jin, M;
EMBO molecular medicine
Species: Mouse
Sample Types: Plasma, Peritoneal Lavage Fluid
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High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification
Authors: Macrì, F;Vigorito, I;Castiglione, S;Faggiano, S;Casaburo, M;Fanotti, N;Piacentini, L;Vigetti, D;Vinci, MC;Raucci, A;
Biomolecules
Species: Human
Sample Types: Cell Culture Supernates
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Evaluation of high dose N- Acetylcysteine on airway inflammation and quality of life outcomes in adults with bronchiectasis: A randomised placebo-controlled pilot study
Authors: Jayaram, L;King, PT;Hunt, J;Lim, M;Park, C;Hu, E;Dousha, L;Ha, P;Bartlett, JB;Southcott, AM;Muruganandan, S;Vogrin, S;Rees, MA;Dean, OM;Wong, CA;
Pulmonary pharmacology & therapeutics
Species: Human
Sample Types: Sputum
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The Protective Role of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Protein Sigma-1 Receptor in Regulating Endothelial Inflammation and Permeability Associated with Acute Lung Injury
Authors: Mahamed, Z;Shadab, M;Najar, RA;Millar, MW;Bal, J;Pressley, T;Fazal, F;
Cells
Species: Human
Sample Types: Cell Culture Supernates
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?-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling
Authors: Kim, HS;Kim, HJ;Hong, YD;Son, ED;Cho, SY;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-?-Induced Inflammatory Phenotypes in Human Skin
Authors: Lee, KS;Kim, Y;Lee, JH;Shon, S;Kim, A;Pham, AVQ;Kim, C;Kim, DH;Kim, YK;Cho, EG;
Cells
Species: Human
Sample Types: Cell Culture Supernates
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Macrophages derived from LPS-stimulated monocytes from individuals with subclinical atherosclerosis were characterized by increased pro-inflammatory activity
Authors: Nikiforov, NG;Kirichenko, TV;Kubekina, MV;Chegodaev, YS;Zhuravlev, AD;Ilchuk, LA;Nikolaeva, MA;Arefieva, AS;Popov, MA;Verkhova, SS;Bagheri Ekta, M;Orekhov, AN;
Cytokine
Species: Human
Sample Types: Cell Culture Supernates
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Design and Fabrication of a 3D-Printed Microfluidic Immunoarray for Ultrasensitive Multiplexed Protein Detection
Authors: Hiniduma, K;Bhalerao, KS;De Silva, PIT;Chen, T;Rusling, JF;
Micromachines
Species: Human
Sample Types: Protein, Serum
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The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi
Authors: Obolski, U;Swarthout, TD;Kalizang'oma, A;Mwalukomo, TS;Chan, JM;Weight, CM;Brown, C;Cave, R;Cornick, J;Kamng'ona, AW;Msefula, J;Ercoli, G;Brown, JS;Lourenço, J;Maiden, MC;French, N;Gupta, S;Heyderman, RS;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
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A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection
Authors: Cholon, DM;Greenwald, MA;Higgs, MG;Quinney, NL;Boyles, SE;Meinig, SL;Minges, JT;Chaubal, A;Tarran, R;Ribeiro, CMP;Wolfgang, MC;Gentzsch, M;
Cells
Species: Human
Sample Types: Cell Culture Supernates
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Formoterol Exerts Anti-Cancer Effects Modulating Oxidative Stress and Epithelial-Mesenchymal Transition Processes in Cigarette Smoke Extract Exposed Lung Adenocarcinoma Cells
Authors: Ferraro, M;Di Vincenzo, S;Lazzara, V;Pinto, P;Patella, B;Inguanta, R;Bruno, A;Pace, E;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Mesenchymal stem cell-derived secretomes-enriched alginate/ extracellular matrix hydrogel patch accelerates skin wound healing
Authors: Kwon, JW;Savitri, C;An, B;Yang, SW;Park, K;
Biomaterials research
Species: Human
Sample Types: Cell Culture Supernates
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Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression
Authors: Zobel, CM;Wenzel, W;Krüger, JP;Baumgarten, U;Wagelöhner, T;Neumann, N;Foroutan, B;Müller, R;Müller, A;Rauschning, D;Schü beta ler, M;Scheit, L;Weinreich, F;Oltmanns, K;Keidel, F;Koch, M;Spethmann, S;Schreiner, M;
Frontiers in microbiology
Species: Human
Sample Types: Serum
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Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma
Authors: Dumitru, CA;Schröder, H;Schäfer, FTA;Aust, JF;Kre beta e, N;Siebert, CLR;Stein, KP;Haghikia, A;Wilkens, L;Mawrin, C;Sandalcioglu, IE;
Cells
Species: Human
Sample Types: Cell Culture Supernates
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Parkin Promotes Airway Inflammatory Response to Interferon Gamma
Authors: Dimasuay, KG;Schaunaman, N;Berg, B;Nichols, T;Chu, HW;
Biomedicines
Species: Human
Sample Types: Cell Culture Supernates
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Stratification of Amniotic Fluid Cells and Amniotic Fluid by Sex Opens Up New Perspectives on Fetal Health
Authors: Campesi, I;Capobianco, G;Cano, A;Lodde, V;Cruciani, S;Maioli, M;Sotgiu, G;Idda, ML;Puci, MV;Ruoppolo, M;Costanzo, M;Caterino, M;Cambosu, F;Montella, A;Franconi, F;
Biomedicines
Species: Human
Sample Types: Amniotic Fluid
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Genomic, transcriptomic, and phenotypic differences among archetype Shigella flexneri strains of serotypes 2a, 3a, and 6
Authors: Gabor, CE;Hazen, TH;Delaine-Elias, BC;Rasko, DA;Barry, EM;
mSphere
Species: Human
Sample Types: Cell Culture Supernates
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Skin microbiota secretomes modulate cutaneous innate immunity against Borrelia burgdorferi s.s
Authors: Baquer, F;Jaulhac, B;Barthel, C;Paz, M;Wolfgramm, J;Müller, A;Boulanger, N;Grillon, A;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties
Authors: Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T;
International immunopharmacology
Species: Human
Sample Types: Cell Culture Supernates
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Enamel Matrix Derivative Suppresses Chemokine Expression in Oral Epithelial Cells
Authors: Panahipour, L;Botta, S;Abbasabadi, AO;Afradi, Z;Gruber, R;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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TNF-? and Poly(I:C) induction of A20 and activation of NF-?B signaling are independent of ABCF1 in human airway epithelial cells
Authors: Cao, QT;Ishak, M;Shpilman, I;Hirota, JA;
Scientific reports
Species: Human
Sample Types: Cell Culture Supernates
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Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins
Authors: Williams, MR;Bagood, MD;Enroth, TJ;Bunch, ZL;Jiang, N;Liu, E;Almoughrabie, S;Khalil, S;Li, F;Brinton, S;Cech, NB;Horswill, AR;Gallo, RL;
Cell reports
Species: Human
Sample Types: Cell Culture Supernates
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Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation
Authors: Shen, CJ;Chan, RH;Lin, BW;Li, NC;Huang, YH;Chang, WC;Chen, BK;
Theranostics
Species: Human
Sample Types: Cell Culture Supernates
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Helicobacter pylori Infection in Infant Rhesus Macaque Monkeys is Associated with an Altered Lung and Oral Microbiome
Authors: Siegel, NA;Jimenez, MT;Rocha, CS;Rolston, M;Dandekar, S;Solnick, JV;Miller, LA;
Research square
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: BALF, Plasma
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Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions
Authors: Faria, J;Ahmed, S;Stamatialis, D;Verhaar, MC;Masereeuw, R;Gerritsen, KGF;Mih?il?, SM;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin
Authors: Leignadier, J;Drago, M;Lesouhaitier, O;Barreau, M;Dashi, A;Worsley, O;Attia-Vigneau, J;
Pharmaceutics
Species: Human
Sample Types: Cell Culture Supernates
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Synergy and oxygen adaptation for development of next-generation probiotics
Authors: Khan, MT;Dwibedi, C;Sundh, D;Pradhan, M;Kraft, JD;Caesar, R;Tremaroli, V;Lorentzon, M;Bäckhed, F;
Nature
Species: Human
Sample Types: Cell Culture Supernates
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Supersulphides provide airway protection in viral and chronic lung diseases
Authors: Matsunaga, T;Sano, H;Takita, K;Morita, M;Yamanaka, S;Ichikawa, T;Numakura, T;Ida, T;Jung, M;Ogata, S;Yoon, S;Fujino, N;Kyogoku, Y;Sasaki, Y;Koarai, A;Tamada, T;Toyama, A;Nakabayashi, T;Kageyama, L;Kyuwa, S;Inaba, K;Watanabe, S;Nagy, P;Sawa, T;Oshiumi, H;Ichinose, M;Yamada, M;Sugiura, H;Wei, FY;Motohashi, H;Akaike, T;
Nature communications
Species: Human
Sample Types: Cell Culture Supernates
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Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells
Authors: Zhou, L;Fang, L;Tamm, M;Stolz, D;Roth, M;
International journal of molecular sciences
Species: Human
Sample Types: Cell Culture Supernates
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Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells
Authors: Kalsi, KK;Jackson, S;Baines, DL;
PloS one
Species: Human
Sample Types: Cell Culture Supernates
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Mild Cognitive Impairment Is Associated with Enhanced Activation of Th17 Lymphocytes in Non-Alcoholic Fatty Liver Disease
Authors: Fiorillo, A;Gallego, JJ;Casanova-Ferrer, F;Giménez-Garzó, C;Urios, A;Ballester, MP;Durbán, L;Rios, MP;Megías, J;San Miguel, T;Kosenko, E;Escudero-García, D;Benlloch, S;Felipo, V;Montoliu, C;
International journal of molecular sciences
Species: Human
Sample Types: Plasma
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Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype
Authors: Warren, KJ;Beck, EM;Callahan, SJ;Helms, MN;Middleton, E;Maddock, S;Carr, JR;Harris, D;Blagev, DP;Lanspa, MJ;Brown, SM;Paine, R;
Respiratory research
Species: Human
Sample Types: BALF
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Unsaturated oxidated fatty acid 12(S)-HETE attenuates TNF-? expression in TNF-?/IFN-?-stimulated human keratinocytes
Authors: Jeon, KB;Kim, J;Lim, CM;Park, JY;Kim, NY;Lee, J;Oh, DK;Yoon, DY;
International immunopharmacology
Species: Human
Sample Types: Cell Culture Supernates
-
Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts
Authors: A Di Nardo, YL Chang, S Alimohamma, K Masuda-Kur, Z Wang, K Sriram, PA Insel
Cell Reports, 2023-04-28;42(5):112453.
Species: Human
Sample Types:
-
Parkin promotes airway inflammatory response to interferon gamma
Authors: Dimasuay, KG;Berg, B;Schaunaman, N;Nichols, T;Chu, HW;
Research square
Species: Human
Sample Types: Cell Culture Supernates
-
Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation
Authors: M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi
Scientific Reports, 2023-03-21;13(1):4656.
Species: Human
Sample Types: Cell Culture Supernates
-
Multi-Species Probiotic Strain Mixture Enhances Intestinal Barrier Function by Regulating Inflammation and Tight Junctions in Lipopolysaccharides Stimulated Caco-2 Cells
Authors: H Han, Y You, S Cha, TR Kim, M Sohn, J Park
Microorganisms, 2023-03-03;11(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Glycolipid-enriched fraction of Osmanthus fragrans inhibits LPS-induced expression of inflammatory genes, COX-2, E-selectin, and Interleukin-8
Authors: T Pirker, EM Pferschy-W, E Bampali, V Bochkov, R Bauer
Journal of ethnopharmacology, 2023-03-02;0(0):116328.
Species: Human
Sample Types: Cell Culture Supenates
-
Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA
Authors: AJ Heires, D Samuelson, D Villageliu, TM Nordgren, DJ Romberger
Scientific Reports, 2023-02-16;13(1):2767.
Species: Human
Sample Types: Cell Culture Supernates
-
Assessment of the mixed origin of the gastric epithelial extracellular vesicles in acellular transfer of Helicobacter pylori toxins and a systematic review
Authors: S Saberi, M Esmaeili, R Saghiri, F Shekari, M Mohammadi
Microbial pathogenesis, 2023-02-08;0(0):106024.
Species: Human
Sample Types: Cell Culture Supernates
-
SCCA1/SERPINB3 promotes suppressive immune environment via STAT-dependent chemokine production, blunting the therapy-induced T cell responses
Authors: L Chen, V Shi, S Wang, R Freeman, F Ruiz, K Jayachandr, J Zhang, P Cosper, L Sun, CJ Luke, C Spina, PW Grigsby, JK Schwarz, S Markovina
bioRxiv : the preprint server for biology, 2023-02-03;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway
Authors: D Tortolani, C Di Meo, S Standoli, F Ciaramella, S Kadhim, E Hsu, C Rapino, M Maccarrone
International Journal of Molecular Sciences, 2023-02-01;24(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Induction of psoriasis- and atopic dermatitis-like phenotypes in 3D skin equivalents with a fibroblast-derived matrix
Authors: B Morgner, J Tittelbach, C Wiegand
Scientific Reports, 2023-01-31;13(1):1807.
Species: Human
Sample Types: Cell Culture Supernates
-
The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure
Authors: D Hinata, R Fukuda, T Okiyoneda
International Journal of Molecular Sciences, 2023-01-24;24(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis
Authors: M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi
PLoS ONE, 2023-01-20;18(1):e0280385.
Species: Human
Sample Types: Cell Culture Supernates
-
Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model
Authors: DT Spiegelbur, M Mannes, A Schultze, F Scheibenbe, F Müller, A Klitzing, DAC Messerer, K Nilsson Ek, B Nilsson, M Huber-Lang, CK Braun
PLoS ONE, 2023-01-12;18(1):e0280069.
Species: Human
Sample Types: Plasma
-
Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release
Authors: G Bredeck, M Busch, A Rossi, B Stahlmecke, KW Fomba, H Herrmann, RPF Schins
Environment international, 2023-01-11;172(0):107732.
Species: Human
Sample Types: Cell Culture Supernates
-
Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses
Authors: TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin
Cell Reports, 2022-12-30;42(1):111905.
Species: Human
Sample Types: Cell Culture Supernates
-
Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway
Authors: K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou
International Journal of Molecular Sciences, 2022-12-23;24(1):.
Species: Human
Sample Types: Cell Culture Supernates
-
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium
Authors: Q Huang, M Peng, Y Gu, J Wu, Y Zhan, Z Deng, S Chen, R Yang, J Chen, J Xie
Oxidative Medicine and Cellular Longevity, 2022-12-19;2022(0):7067623.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study
Authors: LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts
Cytokine, 2022-12-05;162(0):156102.
Species: Human
Sample Types: Cell Culture Supernates
-
Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study
Authors: LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues
Journal of Clinical Medicine, 2022-12-02;11(23):.
Species: Human
Sample Types: Plasma
-
Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFbeta inhibition
Authors: T Luong, E Cukierman
BMC Cancer, 2022-12-02;22(1):1255.
Species: Human
Sample Types: Cell Culture Supernates
-
KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer
Authors: J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi
Cancer Research, 2022-11-15;0(0):OF1-OF14.
Species: Human
Sample Types: Cell Culture Supernates
-
Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model
Authors: E Fournier, J Ratel, S Denis, M Leveque, P Ruiz, C Mazal, F Amiard, M Edely, V Bezirard, E Gaultier, B Lamas, E Houdeau, E Engel, F Lagarde, L Etienne-Me, M Mercier-Bo, S Blanquet-D
Journal of Hazardous Materials, 2022-11-11;443(0):130383.
Species: Human
Sample Types: Cell Culture Supernates
-
Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts
Authors: KEC Blokland, M Nizamoglu, H Habibie, T Borghuis, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess
Frontiers in Pharmacology, 2022-11-03;13(0):989169.
Species: Human
Sample Types: Cell Culture Supernates
-
In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells
Authors: B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang
Cells, 2022-10-28;11(21):.
Species: Human
Sample Types: Cell Culture Supernates
-
GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation
Authors: TY Chu, C Zheng-Géra, KY Huang, YC Chang, YW Chen, KY I, YL Lo, NY Chiang, HY Chen, M Stacey, S Gordon, WY Tseng, CY Sun, YM Wu, YS Pan, CH Huang, CY Lin, TC Chen, K El Omari, M Antonelou, SR Henderson, A Salama, E Seiradake, HH Lin
Nature Communications, 2022-10-27;13(1):6385.
Species: Human
Sample Types: Cell Culture Supernates
-
Negative Magnetic Sorting Preserves the Functionality of Ex Vivo Cultivated Non-Adherent Human Monocytes
Authors: M Hornschuh, V Haas, PP Winkel, MY Gökyildiri, CS Mullins, IM Wrobel, C Manteuffel, E Wirthgen
Biology, 2022-10-27;11(11):.
Species: Human
Sample Types: Cell Culture Supernates
-
Evasion of cGAS and TRIM5 defines pandemic HIV
Authors: L Zuliani-Al, ML Govasli, J Rasaiyaah, C Monit, SO Perry, RP Sumner, S McAlpine-S, C Dickson, KM Rifat Fays, L Hilditch, RJ Miles, F Bibollet-R, BH Hahn, T Boecking, N Pinotsis, LC James, DA Jacques, GJ Towers
Nature Microbiology, 2022-10-26;7(11):1762-1776.
Species: Human
Sample Types: Cell Culture Supernates
-
Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation
Authors: P Marona, J Górka, O Kwapisz, J Jura, J Rys, RM Hoffman, K Miekus
Cell Death & Disease, 2022-09-22;13(9):814.
Species: Human, Mouse
Sample Types: Cell Culture Supernates, Plasma
-
Simultaneous Detection of RIG-1, MDA5, and IFIT-1 Expression Is a Convenient Tool for Evaluation of the Interferon-Mediated Response
Authors: AA Lozhkov, MA Plotnikova, MA Egorova, IL Baranovska, EA Elpaeva, SA Klotchenko, AV Vasin
Viruses, 2022-09-21;14(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
Microplastics: What happens in the human digestive tract? First evidences in adults using in vitro gut models
Authors: E Fournier, M Leveque, P Ruiz, J Ratel, C Durif, S Chalancon, F Amiard, M Edely, V Bezirard, E Gaultier, B Lamas, E Houdeau, F Lagarde, E Engel, L Etienne-Me, S Blanquet-D, M Mercier-Bo
Journal of Hazardous Materials, 2022-09-21;442(0):130010.
Species: Human
Sample Types: Cell Culture Supernates
-
Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts
Authors: M Patankar, M Li, A Khalatbari, JD Castle, L Hu, C Zhang, A Shaker
International Journal of Molecular Sciences, 2022-09-08;23(18):.
Species: Human
Sample Types: Cell Culture Supernatants
-
Airway epithelial immunoproteasome subunit LMP7 protects against rhinovirus infection
Authors: KG Dimasuay, N Schaunaman, B Berg, D Cervantes, E Kruger, FL Heppner, DA Ferrington, HW Chu
Scientific Reports, 2022-08-25;12(1):14507.
Species: Human
Sample Types: Cell Lysates
-
Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity
Authors: L Sansone, A de Iure, M Cristina, M Belli, L Vitiello, F Marcolongo, A Rosellini, L Macera, PG Spezia, C Tomino, S Bonassi, MA Russo, F Maggi, P Russo
International Journal of Molecular Sciences, 2022-08-22;23(16):.
Species: Human
Sample Types: Cell Culture Supernates
-
Gentle Touch Therapy, Pain Relief and Neuroplasticity at Baseline in Fibromyalgia Syndrome: A Randomized, Multicenter Trial with Six-Month Follow-Up
Authors: ASI Salgado, MH Takemoto, CFTC de Souza, DC Salm, D da Rosa, GC Cardoso, DD Ludtke, SFC Soares, JK Ferreira, AR Dutra, YC Szeremeta, G Mazzardo, J Mayra, DDL Sheffer, W Caumo, EB Bittencour, R Schleip, A Latini, F Bobinski, DF Martins
Journal of Clinical Medicine, 2022-08-20;11(16):.
Species: Human
Sample Types: Serum
-
SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity
Authors: C Amormino, V Tedeschi, G Paldino, S Arcieri, MT Fiorillo, A Paiardini, L Tuosto, M Kunkl
Cells, 2022-08-15;11(16):.
Species: Human
Sample Types: Cell Culture Supernates
-
Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells
Authors: M Busch, G Bredeck, F Waag, K Rahimi, H Ramachandr, T Bessel, S Barcikowsk, A Herrmann, A Rossi, RPF Schins
Biomolecules, 2022-08-09;12(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation
Authors: DC Humphries, R Mills, C Boz, BJ McHugh, N Hirani, AG Rossi, A Pedersen, HT Schambye, RJ Slack, H Leffler, UJ Nilsson, W Wang, T Sethi, AC Mackinnon
Frontiers in Pharmacology, 2022-08-08;13(0):949264.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells
Authors: JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer
Scientific Reports, 2022-08-01;12(1):13202.
Species: Human
Sample Types: Cell Culture Supernates
-
Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis
Authors: S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek
Journal of ovarian research, 2022-07-26;15(1):87.
Species: Human
Sample Types: Cell Culture Supernates
-
The role of CFA/I in adherence and toxin delivery by ETEC expressing multiple colonization factors in the human enteroid model
Authors: EM Smith, CL Grassel, A Papadimas, J Foulke-Abe, EM Barry
PloS Neglected Tropical Diseases, 2022-07-26;16(7):e0010638.
Species: Human
Sample Types: Cell Culture Supernates
-
Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems
Authors: LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt
Scientific Reports, 2022-07-20;12(1):12448.
Species: Human
Sample Types: Cell Culture Supernates
-
Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1
Authors: H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd
Mucosal Immunology, 2022-07-15;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells
Authors: K Ueno-Shuto, S Kamei, M Hayashi, A Fukuyama, Y Uchida, N Tokutomi, MA Suico, H Kai, T Shuto
International Journal of Molecular Sciences, 2022-07-13;23(14):.
Species: Human
Sample Types: Cell Culture Supernates
-
Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression
Authors: M Anselmi, F Fontana, M Marzagalli, N Gagliano, M Sommariva, P Limonta
Cancers, 2022-07-13;14(14):.
Species: Human
Sample Types: Cell Culture Supernates
-
Digested Human Colostrum Reduces Interleukin-8 Production in Induced Human Intestinal Epithelial Cells
Authors: Y Lyu, Y Chen
Nutrients, 2022-07-06;14(14):.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds
Authors: A Moniot, J Braux, R Siboni, C Guillaume, S Audonnet, I Allart-Sim, J Sapi, R Tirouvanzi, S Gérard, SC Gangloff, F Velard
International Journal of Molecular Sciences, 2022-06-29;23(13):.
Species: Human
Sample Types: Cell Culture Supernates
-
Establishment of Repeated In Vitro Exposure System for Evaluating Pulmonary Toxicity of Representative Criteria Air Pollutants Using Advanced Bronchial Mucosa Models
Authors: S Upadhyay, A Chakrabort, TA Thimraj, M Baldi, A Steneholm, K Ganguly, P Gerde, L Ernstgård, L Palmberg
Oncogene, 2022-05-24;10(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus
Authors: JT de Kay, J Carver, B Shevenell, AM Kosta, S Tsibulniko, E Certo, DB Sawyer, S Ryzhov, MP Robich
Cellular Signalling, 2022-05-21;96(0):110360.
Species: Human
Sample Types: Plasma
-
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease
Authors: Y Zhan, J Chen, J Wu, Y Gu, Q Huang, Z Deng, S Chen, X Wu, Y Lv, Z Zeng, J Xie
Respiratory Research, 2022-05-12;23(1):120.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of Spleen Tyrosine Kinase Restores Glucocorticoid Sensitivity to Improve Steroid-Resistant Asthma
Authors: Q Liu, L Hua, C Bao, L Kong, J Hu, C Liu, Z Li, S Xu, X Liu
Frontiers in Pharmacology, 2022-05-05;13(0):885053.
Species: Human
Sample Types: Cell Culture Supernates
-
IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
Authors: L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder
Cells, 2022-04-30;11(9):.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells
Authors: E Filidou, L Kandilogia, G Tarapatzi, M Spathakis, P Steiropoul, D Mikroulis, K Arvanitidi, V Paspaliari, G Kolios
International Journal of Molecular Sciences, 2022-04-20;23(9):.
Species: Human
Sample Types: Cell Culture Supernates
-
Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation
Authors: K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi
Scientific Reports, 2022-04-11;12(1):5181.
Species: Human
Sample Types: Cell Culture Supernates
-
Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability
Authors: H Janbazacya, J van Bergen, S Varasteh, J Garssen, G Folkerts, S Braber
Cytokine, 2022-04-08;154(0):155878.
Species: Human
Sample Types: Cell Culture Supernates
-
In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release
Authors: M Dolci, L Signorini, S D'Alessand, F Perego, S Parapini, M Sommariva, D Taramelli, P Ferrante, N Basilico, S Delbue
International Journal of Molecular Sciences, 2022-04-06;23(7):.
Species: Human
Sample Types: Cell Culture Supernates
-
Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts
Authors: S Novello, S Tricot-Dol, A Novella, P Pellen-Mus, S Jeanne
Pharmaceutics, 2022-03-28;14(4):.
Species: Human
Sample Types: Cell Culture Supernates
-
Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8
Authors: T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen, F Tran, P Griebel, D Albrecht, A Ahmed, M Suarez-Car, A Jiménez-Sá, T Beikert, A Tietz-Dahl, AN Menevse, G Schmidt, M Brom, JHW Pahl, W Antonopoul, M Miller, RL Perez, F Bestvater, NA Giese, P Beckhove, P Rosenstiel, D Jäger, O Strobel, D Pe'er, N Halama, J Debus, A Cerwenka, PE Huber
Science Advances, 2022-03-23;8(12):eabh4050.
Species: Human
Sample Types: Serum
-
Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence
Authors: E Lieschke, Z Wang, C Chang, CE Weeden, GL Kelly, A Strasser
Cell Death and Differentiation, 2022-03-09;0(0):.
Species: Human
Sample Types: Serum
-
A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site
Authors: G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown
Scientific Reports, 2022-03-07;12(1):3990.
Species: Human
Sample Types: Blister Fluid
-
Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women
Authors: A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith
Cells, 2022-03-01;11(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing
Authors: AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl
Cells, 2022-02-23;11(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications
Authors: OF McElvaney, T Asakura, SL Meinig, JL Torres-Cas, RS Hagan, C Gabillard, MP Murphy, LB Thorne, A Borczuk, EP Reeves, RE Zumwalt, Y Mikami, TP Carroll, K Okuda, G Hogan, OJ McElvaney, J Clarke, NL McEvoy, PW Mallon, C McCarthy, G Curley, MC Wolfgang, RC Boucher, NG McElvaney
EBioMedicine, 2022-02-22;77(0):103894.
Species: Human
Sample Types: Plasma
-
Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models
Authors: J Queen, JC Domingue, JR White, C Stevens, B Udayasurya, TTD Nguyen, S Wu, H Ding, H Fan, M McMann, A Corona, TC Larman, SS Verbridge, F Housseau, DJ Slade, JL Drewes, CL Sears
MBio, 2022-02-08;0(0):e0299121.
Species: Human
Sample Types: Cell Culture Supernates
-
Antibody microarray analysis of amniotic fluid proteomes in women with cervical insufficiency and short cervix, and their association with pregnancy latency length
Authors: S Hong, KH Park, YE Lee, JE Lee, YM Kim, E Joo, I Cho
PLoS ONE, 2022-02-07;17(2):e0263586.
Species: Human
Sample Types: Amniotic Fluid
-
Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment
Authors: V Schimek, K Strasser, A Beer, S Göber, N Walterskir, C Brostjan, C Müller, T Bachleitne, M Bergmann, H Dolznig, R Oehler
Cell Death & Disease, 2022-02-04;13(2):113.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air-Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs)
Authors: S Offer, E Hartner, S Di Bucchia, C Bisig, S Bauer, J Pantzke, EJ Zimmermann, X Cao, S Binder, E Kuhn, A Huber, S Jeong, U Käfer, P Martens, A Mesceriako, J Bendl, R Brejcha, A Buchholz, D Gat, T Hohaus, N Rastak, G Jakobi, M Kalberer, T Kanashova, Y Hu, C Ogris, A Marsico, F Theis, M Pardo, T Gröger, S Oeder, J Orasche, A Paul, T Ziehm, ZH Zhang, T Adam, O Sippula, M Sklorz, J Schnelle-K, H Czech, A Kiendler-S, Y Rudich, R Zimmermann
Environmental health perspectives, 2022-02-03;130(2):27003.
Species: Human
Sample Types: Cell Culture Supernates
-
Echinococcus multilocularis specific antibody, systemic cytokine, and chemokine levels, as well as antigen-specific cellular responses in patients with progressive, stable, and cured alveolar echinococcosis: A 10-year follow-up
Authors: B Grüner, L Peters, A Hillenbran, P Vo beta berg, J Schweiker, EG Rollmann, LH Rodriguez, J Blumhardt, S Burkert, P Kern, C Köhler, PT Soboslay
PloS Neglected Tropical Diseases, 2022-02-02;16(2):e0010099.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement
Authors: C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert
International Journal of Molecular Sciences, 2022-01-28;23(3):.
Species: Human
Sample Types: Cell Culture Supernates
-
Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma
Authors: S Saxena, C Molczyk, A Purohit, E Ehrhorn, P Goel, DR Prajapati, P Atri, S Kaur, PM Grandgenet, MA Hollingswo, SK Batra, RK Singh
American journal of cancer research, 2022-01-15;12(1):68-90.
Species: Human
Sample Types: Serum
-
MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema
Authors: Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie
Oxidative Medicine and Cellular Longevity, 2022-01-07;2022(0):9300269.
Species: Human
Sample Types: Cell Culture Supernates
-
Slow degrading Mg-based materials induce tumor cell dormancy on an osteosarcoma-fibroblast coculture model
Authors: P Globig, R Willumeit-, F Martini, E Mazzoni, BJC Luthringer
Bioactive materials, 2021-12-30;16(0):320-333.
Species: Human
Sample Types: Cell Culture Supernates
-
Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells
Authors: AA Giese, A Babendreye, P Krappen, A Gross, P Strnad, S Düsterhöft, A Ludwig
Scientific Reports, 2021-12-20;11(1):24230.
Species: Human
Sample Types: Cell Culture Supernates
-
Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity
Authors: M Rahman, M Irmler, S Keshavan, M Introna, J Beckers, L Palmberg, G Johanson, K Ganguly, S Upadhyay
Viruses, 2021-12-17;13(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma
Authors: A Tosi, L Nardinocch, ML Carbone, L Capriotti, E Pagani, S Mastroeni, C Fortes, F Scopelliti, C Cattani, F Passarelli, A Rosato, S D'Atri, CM Failla, A Cavani
Biomedicines, 2021-12-16;9(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins
Authors: R Roca-Pinil, R Holani, A López-Cano, C Saubi, R Baltà-Foix, ER Cobo, E Garcia-Fru, A Arís
Scientific Reports, 2021-12-10;11(1):23798.
Species: Human
Sample Types: Cell Culture Supernates
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Infection with a hypervirulent strain of Helicobacter pylori primes gastric cells toward intestinal transdifferentiation
Authors: S Saberi, M Esmaeili, M Tashakorip, M Eshagh Hos, H Baharvand, M Mohammadi
Microbial pathogenesis, 2021-12-08;162(0):105353.
Species: Human
Sample Types: Cell Culture Supernates
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Toxicological transcriptome of human airway constructs after exposure to indoor air particulate matter: In search of relevant pathways of moisture damage-associated health effects
Authors: ME Nordberg, M Täubel, S Heikkinen, K Jalkanen, A Köliö, M Stranger, H Leppänen, A Hyvärinen, K Huttunen
Environment international, 2021-11-26;158(0):106997.
Species: Human
Sample Types: Cell Culture Supernates
-
miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes
Authors: K Dull, F Fazekas, D Deák, D Kovács, S Póliska, A Szegedi, CC Zouboulis, D Tör?csik
Scientific Reports, 2021-11-02;11(1):21510.
Species: Human
Sample Types: Cell Culture Supernates
-
DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen
Authors: SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy
International Journal of Molecular Sciences, 2021-10-15;22(20):.
Species: Human
Sample Types: Cell Culture Supernates
-
A highly efficient method for the production and purification of recombinant human CXCL8
Authors: S McKenna, SP Giblin, RA Bunn, Y Xu, SJ Matthews, JE Pease
PLoS ONE, 2021-10-15;16(10):e0258270.
Species: Human
Sample Types: Recombinant Protein
-
Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis
Authors: X Zhu, Y Zhan, Y Gu, Q Huang, T Wang, Z Deng, J Xie
Frontiers in Physiology, 2021-10-08;12(0):733650.
Species: Human
Sample Types: Cell Culture Supernates
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Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors
Authors: L Liu, E Bankell, C Rippe, B Morén, KG Stenkula, BO Nilsson, K Swärd
Frontiers in Physiology, 2021-10-04;12(0):732564.
Species: Human
Sample Types: Cell Lysates
-
Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
Authors: P Jiang, Y Zhang, B Ru, Y Yang, T Vu, R Paul, A Mirza, G Altan-Bonn, L Liu, E Ruppin, L Wakefield, KW Wucherpfen
Nature methods, 2021-09-30;18(10):1181-1191.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming
Authors: N Niu, J Yao, RC Bast, AK Sood, J Liu
Oncogenesis, 2021-09-29;10(9):65.
Species: Human
Sample Types: Cell Culture Supernates
-
Multi-level inhibition of coronavirus replication by chemical ER stress
Authors: MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht
Nature Communications, 2021-09-20;12(1):5536.
Species: Human
Sample Types: Cell Culture Supernates
-
Pulmonary function changes in older adults with and without metabolic syndrome
Authors: MAR Brandao-Ra, R Moraes-Fer, MC Oliveira-J, A Santos-Dia, ALL Bachi, G Gabriela-P, S de Oliveir, AC Araújo-Ros, LVF Oliveira, CR Frison, WL do Prado, RP Raju, PB Balagopal, RP Vieira
Scientific Reports, 2021-08-30;11(1):17337.
Species: Human
Sample Types: Exhaled Breath Condensate (EBC)
-
Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1alpha kinase inhibitor KIRA6 through HSP60 targeting
Authors: N Rufo, D Korovesis, S Van Eygen, R Derua, AD Garg, F Finotello, M Vara-Perez, J Rožanc, M Dewaele, PA de Witte, LG Alexopoulo, S Janssens, L Sinkkonen, T Sauter, SHL Verhelst, P Agostinis
Cell Death and Differentiation, 2021-08-27;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass
Authors: M Lesouhaiti, M Gregoire, A Gacouin, V Coirier, A Frerou, C Piau, V Cattoir, E Dumontet, M Revest, P Tattevin, A Roisne, JP Verhoye, E Flecher, Y Le Tulzo, K Tarte, JM Tadié
Journal of leukocyte biology, 2021-08-23;0(0):.
Species: Human
Sample Types: Plasma
-
Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection
Authors: G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi
PloS Biology, 2021-08-19;19(8):e3001387.
Species: Human
Sample Types: Plasma
-
The toxicity of Aspidosperma subincanum to MCF7 cells is related to modulation of oxidative status and proinflammatory pathways
Authors: AF Santos, NSR Santos Mot, EM Schiefer, RS da Cunha, AM Junkert, AEM Stinghen, R Pontarolo, AR Crisma, AM Weffort-Sa, RC Pedrosa, WM de Souza, KB Felipe
Journal of ethnopharmacology, 2021-08-09;0(0):114512.
Species: Human
Sample Types: Cell Culture Supernates
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Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction
Authors: Z Cui, H Dabas, BC Leonard, JV Shiah, JR Grandis, DE Johnson
Cell Death & Disease, 2021-08-06;12(8):775.
Species: Human
Sample Types: Cell Culture Supernates
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Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes
Authors: E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz
Biology, 2021-08-04;10(8):.
Species: Human
Sample Types: Cell Culture Supernates
-
The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells
Authors: J Cui, C Duizer, LI Bouwman, KS van Rooije, CGP Voogdt, JPM van Putten, MR de Zoete
PloS Pathogens, 2021-08-02;17(8):e1009787.
Species: Human
Sample Types: Cell Culture Supernates
-
Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis
Authors: L Kandilogia, E Filidou, I Drygiannak, G Tarapatzi, S Didaskalou, M Koffa, K Arvanitidi, G Bamias, V Valatas, V Paspaliari, G Kolios
Stem Cells International, 2021-07-27;2021(0):9929461.
Species: Human
Sample Types: Cell Culture Supernates
-
LYSMD3: A mammalian pattern recognition receptor for chitin
Authors: X He, BA Howard, Y Liu, AK Neumann, L Li, N Menon, T Roach, SD Kale, DC Samuels, H Li, T Kite, H Kita, TY Hu, M Luo, CN Jones, UJ Okaa, DL Squillace, BS Klein, CB Lawrence
Cell Reports, 2021-07-20;36(3):109392.
Species: Human
Sample Types: Cell Culture Supernates
-
Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells
Authors: B Falcones, H Sanz-Frail, E Marhuenda, I Mendizábal, I Cabrera-Ag, N Malandain, JJ Uriarte, I Almendros, D Navajas, DJ Weiss, R Farré, J Otero
Polymers, 2021-07-18;13(14):.
Species: Human
Sample Types: Cell Culture Supernates
-
Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells
Authors: Y Hosokawa, I Hosokawa, K Ozaki
Mediators of Inflammation, 2021-07-10;2021(0):5535844.
Species: Human
Sample Types: Cell Culture Supernates
-
ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice
Authors: JS Bourgeois, L Wang, AF Rabino, J Everitt, MI Alvarez, S Awadia, ES Wittchen, R Garcia-Mat, DC Ko
PloS Pathogens, 2021-07-09;17(7):e1009713.
Species: Human
Sample Types: Cell Culture Supernates
-
Characterization of low-density granulocytes in COVID-19
Authors: LE Cabrera, PT Pekkarinen, M Alander, KHA Nowlan, NA Nguyen, S Jokiranta, S Kuivanen, A Patjas, S Mero, SH Pakkanen, S Heinonen, A Kantele, O Vapalahti, E Kekäläinen, T Strandin
PloS Pathogens, 2021-07-06;17(7):e1009721.
Species: Human
Sample Types: Serum
-
Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
Authors: KEC Blokland, H Habibie, T Borghuis, GJ Teitsma, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess
Cells, 2021-06-29;10(7):.
Species: Human
Sample Types: Cell Culture Supernates
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An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles
Authors: M Busch, AAM Kämpfer, RPF Schins
Chemosphere, 2021-06-28;284(0):131345.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production
Authors: YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang
Arthritis Research & Therapy, 2021-06-16;23(1):171.
Species: Human
Sample Types: Cell Culture Supernates
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Food Contaminants Effects on an In Vitro Model of Human Intestinal Epithelium
Authors: M Guibourden, J Haug, N Chevalier, M Spatz, N Barbezier, J Gay-Quéhei, PM Anton
Toxics, 2021-06-09;9(6):.
Species: Human
Sample Types: Cell Culture Supernates
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Bacterial genotoxins induce T�cell senescence
Authors: SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard
Cell Reports, 2021-06-08;35(10):109220.
Species: Human
Sample Types: Cell Culture Supernates
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Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response
Authors: M Sueiro-Oli, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, Y Yu, M Strobel, C Cunha, D Thomson, R Fortune-Gr, S Thusek, P Bowyer, A Beilhack, A Carvalho, E Bignell, MR Filipovic, J Amich
PloS Biology, 2021-06-01;19(6):e3001247.
Species: Human
Sample Types: Cell Culture Supernates
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HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
Authors: L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang
Autophagy, 2021-05-24;0(0):1-20.
Species: Rat
Sample Types: Serum
-
Synergistic cycles of protease activity and inflammation via PPAR&gamma degradation in chronic obstructive pulmonary disease
Authors: N Kwak, KH Lee, J Woo, J Kim, CH Lee, CG Yoo
Experimental & Molecular Medicine, 2021-05-21;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Inflammatory responses to metal oxide ceramic nanopowders
Authors: S Jamieson, A Mawdesley, D Deehan, J Kirby, J Holland, A Tyson-Capp
Scientific Reports, 2021-05-18;11(1):10531.
Species: Human
Sample Types: Cell Culture Supernates
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Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration
Authors: HK Skovdahl, S Gopalakris, TD Svendsen, AVB Granlund, I Bakke, ZG Ginbot, S Thorsvik, A Flatberg, B Sporsheim, J Ostrop, TE Mollnes, AK Sandvik, T Bruland
Frontiers in Pharmacology, 2021-05-13;12(0):679741.
Species: Human
Sample Types: Cell Culture Supernates
-
Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients
Authors: W Johnston, BT Rosier, A Artacho, M Paterson, K Piela, C Delaney, JL Brown, G Ramage, A Mira, S Culshaw
Scientific Reports, 2021-05-07;11(1):9796.
Species: Human
Sample Types: Saliva
-
Plasma markers in pulmonary hypertension subgroups correlate with patient survival
Authors: T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars
Respiratory Research, 2021-05-04;22(1):137.
Species: Human
Sample Types: Plasma
-
Higher CD4/CD8 ratio of pleural effusion predicts better survival for lung cancer patients receiving immune checkpoint inhibitors
Authors: PH Lee, TY Yang, KC Chen, YH Huang, JS Tseng, KH Hsu, YC Wu, KJ Liu, GC Chang
Scientific Reports, 2021-04-30;11(1):9381.
Species: Human
Sample Types: Pleural Effusion
-
Activation of NF-&kapppaB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion
Authors: X Zhou, LJ Backman, P Danielson
Scientific Reports, 2021-04-01;11(1):7360.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin-8 genetic diversity, haplotype structure and production differ in two ethnically distinct South African populations
Authors: M Paximadis, ACP Picton, D Sengupta, M Ramsay, A Puren, CT Tiemessen
Cytokine, 2021-04-01;0(0):155489.
Species: Human
Sample Types: Cell Culture Supernates
-
Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
Authors: L Wang, D Aschenbren, Z Zeng, X Cao, D Mayr, M Mehta, M Capitani, N Warner, J Pan, L Wang, Q Li, T Zuo, S Cohen-Keda, J Lu, RC Ardy, DJ Mulder, D Dissanayak, K Peng, Z Huang, X Li, Y Wang, X Wang, S Li, S Bullers, AN Gammage, K Warnatz, AI Schiefer, G Krivan, V Goda, WHA Kahr, M Lemaire, Genomics E, CY Lu, I Siddiqui, MG Surette, D Kotlarz, KR Engelhardt, HR Griffin, R Rottapel, H Decaluwe, RM Laxer, M Proietti, S Hambleton, S Elcombe, CH Guo, B Grimbacher, I Dotan, SC Ng, SA Freeman, SB Snapper, C Klein, K Boztug, Y Huang, D Li, HH Uhlig, AM Muise
Nature Genetics, 2021-03-29;53(4):500-510.
Species: Human
Sample Types: Cell Culture Supernates
-
Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets
Authors: SH Kim, SH Hong, JH Lee, DH Lee, K Jung, JY Yang, HS Shin, J Lee, J Jeong, JH Oh
Toxics, 2021-03-17;9(3):.
Species: Human
Sample Types: cell culture supernatant
-
Production of IL-1&beta, IL-6 and CXCL8 by endometrium of crossbred heifers stimulated with various pathogen-associated molecular patterns
Authors: PP Nunes, TDM Martins, AC Leite, EBM Silva, TA da Paixão, RL Santos, ÁM Borges
Animal reproduction science, 2021-03-17;228(0):106736.
Species: Bovine
Sample Types: Cell Culture Supernates
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Polymicrobial stimulation of human fetal membranes induce neutrophil activation and neutrophil extracellular trap release
Authors: M Tong, SE Hanna, VM Abrahams
Journal of reproductive immunology, 2021-03-09;145(0):103306.
Species: Human
Sample Types: Cell Culture Supernates
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Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response
Authors: MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad
Cell Death & Disease, 2021-03-04;12(3):241.
Species: Human
Sample Types: Cell Culture Supernates
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Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
Authors: N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton
Nature Communications, 2021-02-22;12(1):1209.
Species: Human
Sample Types: Cell Culture Supernates
-
Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation
Authors: GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio
Biomolecules, 2021-02-21;11(2):.
Species: Human
Sample Types: Plasma
-
Genetic variation in Toll-like receptor-5 and colonization with flagellated bacterial vaginosis-associated bacteria
Authors: EJ Dela Cruz, TL Fiedler, C Liu, MM Munch, CM Kohler, AR Oot, JM Wallis, J Wang, A Frishman, K Garcia, A Wiser, JE Balkus, S Srinivasan, JL Golob, LK Sycuro, JM Marrazzo, TR Hawn, DN Fredricks
Infect Immun, 2021-02-16;0(0):.
Species: Human
Sample Types: Vaginal Swab
-
Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma
Authors: JI Alexander, DB Vendramini, R Francescon, T Luong, J Franco-Bar, N Shah, JC Gardiner, E Nicolas, KS Raghavan, E Cukierman
Scientific Reports, 2021-02-15;11(1):3802.
Species: Human
Sample Types: Cell Culture Supernates
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Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy?
Authors: P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski
Arthritis Research & Therapy, 2021-02-15;23(1):56.
Species: Human
Sample Types: Cell Culture Supernates
-
PHAIR: a biosensor for pH measurement in air-liquid interface cell culture
Authors: M Dabaghi, N Saraei, G Xu, A Chandiramo, J Yeung, JP Nguyen, M Vukmirovic, PR Selvaganap, JA Hirota
Scientific Reports, 2021-02-10;11(1):3477.
Species: Human
Sample Types: Cell Culture Supernates
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Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway
Authors: MS Coates, EWFW Alton, GW Rapeport, JC Davies, K Ito
PLoS ONE, 2021-02-01;16(2):e0246050.
Species: Human
Sample Types: Cell Culture Supernates
-
Early bilirubinemia after allogeneic stem cell transplantation-an endothelial complication
Authors: H Dai, O Penack, A Radujkovic, D Schult, J Majer-Laut, IW Blau, L Bullinger, S Jiang, C Müller-Tid, P Dreger, T Luft
Bone marrow transplantation, 2021-01-30;0(0):.
Species: Human
Sample Types: Serum
-
The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells
Authors: Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo
BioMed Research International, 2021-01-28;2021(0):8826586.
Species: Human
Sample Types: Cell Culture Supernates
-
Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity
Authors: M Heydarian, M Schweinlin, T Schwarz, R Rawal, H Walles, M Metzger, T Rudel, V Kozjak-Pav
Journal of tissue engineering, 2021-01-28;12(0):2041731420988.
Species: Human
Sample Types: Cell Culture Supernates
-
Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages
Authors: SM Anil, N Shalev, AC Vinayaka, S Nadarajan, D Namdar, E Belausov, I Shoval, KA Mani, G Mechrez, H Koltai
Scientific Reports, 2021-01-14;11(1):1462.
Species: Human
Sample Types: Cell Culture Supernates
-
A protein microarray analysis of amniotic fluid proteins for the prediction of spontaneous preterm delivery in women with preterm premature rupture of membranes at 23 to 30 weeks of gestation
Authors: HJ Kim, KH Park, YM Kim, E Joo, K Ahn, S Shin
PLoS ONE, 2020-12-31;15(12):e0244720.
Species: Human
Sample Types: Amniotic Fluid
-
Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages
Authors: LJ Williams, SG Tristram, GR Zosky
International Journal of Environmental Research and Public Health, 2020-12-28;18(1):.
Species: Human
Sample Types: Cell Culture Supernates
-
Resveratrol treatment reduces expression of MCP-1, IL-6, IL-8 and RANTES in endometriotic stromal cells
Authors: R Kolahdouz-, F Shidfar, S Khodaverdi, T Arablou, S Heidari, N Rashidi, AA Delbandi
Journal of Cellular and Molecular Medicine, 2020-12-15;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
SARS-CoV-2-specific IgA and limited inflammatory cytokines are present in the stool of select patients with acute COVID-19
Authors: GJ Britton, A Chen-Liaw, F Cossarini, AE Livanos, MP Spindler, T Plitt, J Eggers, I Mogno, A Gonzalez-R, S Siu, M Tankelevic, L Grinspan, RE Dixon, D Jha, G Martinez-D, F Amanat, DA Hoagland, B tenOever, MC Dubinsky, M Merad, H van Bakel, F Krammer, G Bongers, S Mehandru, JJ Faith
medRxiv : the preprint server for health sciences, 2020-12-09;0(0):.
Species: Human
Sample Types: Fecal Supernates
-
Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist
Authors: H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier
Frontiers in Pharmacology, 2020-12-08;11(0):598702.
Species: Human
Sample Types: Cell Culture Supernates
-
ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes
Authors: S Niklander, D Bandaru, DW Lambert, KD Hunter
FEBS Open Bio, 2020-11-06;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features
Authors: M Kameda, M Otsuka, H Chiba, K Kuronuma, T Hasegawa, H Takahashi, H Takahashi
PLoS ONE, 2020-11-02;15(11):e0241719.
Species: Human
Sample Types: Serum
-
Salivary IL-8 and IL-1RA changes induced by exercise in cold-dry and normal conditions
Authors: I Patlan, MP Jeffrey, D Lewis, J Green-John, S Dogra
Cytokine, 2020-10-28;137(0):155347.
Species: Human
Sample Types: Saliva
-
An observational study of innate immune responses in patients with acute appendicitis
Authors: T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens
Sci Rep, 2020-10-15;10(1):17352.
Species: Human
Sample Types: Cell Culture Supernates
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Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy
Authors: M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg
Mol Ther, 2020-10-15;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM
Authors: G Kaufman, D Skrtic
Int J Mol Sci, 2020-10-03;21(19):.
Species: Human
Sample Types: Cell Culture Supernates
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Perfluorooctanoic acid in indoor particulate matter triggers oxidative stress and inflammation in corneal and retinal cells
Authors: PT Tien, HJ Lin, YY Tsai, YP Lim, CS Chen, CY Chang, CJ Lin, JJ Chen, SM Wu, YJ Huang, L Wan
Scientific Reports, 2020-09-24;10(1):15702.
Species: Human
Sample Types: Whole Cells
-
Neutrophils produce proinflammatory or anti-inflammatory extracellular vesicles depending on the environmental conditions
Authors: F Kolonics, E Kajdácsi, VJ Farkas, DS Veres, D Khamari, Á Kittel, ML Merchant, KR McLeish, ÁM L?rincz, E Ligeti
J. Leukoc. Biol., 2020-09-18;0(0):.
Species: Human
Sample Types: Cell Supernates
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Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding
Authors: A Iannucci, V Caneparo, S Raviola, I Debernardi, D Colangelo, R Miggiano, G Griffante, S Landolfo, M Gariglio, M De Andrea
PLoS Pathog., 2020-09-09;16(9):e1008811.
Species: Human
Sample Types: Cell Culture Supernates
-
Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells
Authors: YD Jung, SK Park, D Kang, S Hwang, MH Kang, SW Hong, JH Moon, JS Shin, DH Jin, D You, JY Lee, YY Park, JJ Hwang, CS Kim, N Suh
Redox Biol, 2020-09-09;37(0):101716.
Species: Human
Sample Types: Cell Culture Supernates
-
Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi�strains unveil a role for fibroblasts in neutrophil recruitment and activation
Authors: AER Oliveira, MCA Pereira, AT Belew, LRP Ferreira, LMN Pereira, EGA Neves, MDCP Nunes, BA Burleigh, WO Dutra, NM El-Sayed, RT Gazzinelli, SMR Teixeira
PLoS Pathog., 2020-08-18;16(8):e1008781.
Species: Human
Sample Types: Cell Culture Supernates
-
Identification and toxicological evaluation of cyclic sulfonium ion degradation products of sulphur mustard
Authors: P Hemström, KH Holmgren, BE Hammarströ, A Larsson, A Östin
Mar. Environ. Res., 2020-08-07;162(0):105047.
Species: Human
Sample Types: Cell Culture Supernates
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Translational research into the effects of cigarette smoke on inflammatory mediators and epithelial TRPV1 in Crohn's disease
Authors: L Allais, S Verschuere, T Maes, R De Smet, S Devriese, GB Gonzales, H Peeters, K Van Crombr, C Bachert, M De Vos, GG Brusselle, KR Bracke, CA Cuvelier, D Laukens
PLoS ONE, 2020-08-06;15(8):e0236657.
Species: Human
Sample Types: Cell Culture Supernates
-
SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells
Authors: AE Wyman, TTT Nguyen, P Karki, ME Tulapurkar, CO Zhang, J Kim, TG Feng, AJ Dabo, NW Todd, IG Luzina, P Geraghty, RF Foronjy, JD Hasday, AA Birukova, SP Atamas, KG Birukov
Sci Rep, 2020-07-27;10(1):12497.
Species: Human
Sample Types: Cell Culture Supernates
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Extracellular Vesicles Produced by the Probiotic Propionibacterium freudenreichii CIRM-BIA 129 Mitigate Inflammation by Modulating the NF-&kappaB Pathway
Authors: VR Rodovalho, BSR da Luz, H Rabah, FLR do Carmo, EL Folador, A Nicolas, J Jardin, V Briard-Bio, H Blottière, N Lapaque, G Jan, Y Le Loir, VA de Carvalh, E Guédon
Front Microbiol, 2020-07-07;11(0):1544.
Species: Human
Sample Types: Cell Culture Supernates
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The Delivery of &alpha1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore
Authors: S Tumpara, B Martinez-D, G Gomez-Mari, B Liu, DS DeLuca, E Korenbaum, D Jonigk, F Jugert, FM Wurm, MJ Wurm, T Welte, S Janciauski
Front Pharmacol, 2020-07-03;11(0):983.
Species: Human
Sample Types: Cell Culture Supernates
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Altered iron metabolism in cystic fibrosis macrophages: the impact of CFTR modulators and implications for Pseudomonas aeruginosa survival
Authors: HF Hazlett, TH Hampton, DS Aridgides, DA Armstrong, JA Dessaint, DL Mellinger, AB Nymon, A Ashare
Sci Rep, 2020-07-02;10(1):10935.
Species: Human
Sample Types: Whole Cells
-
The microRNA-34a-Induced Senescence-Associated Secretory Phenotype (SASP) Favors Vascular Smooth Muscle Cells Calcification
Authors: E Zuccolo, I Badi, F Scavello, I Gambuzza, L Mancinelli, F Macrì, CC Tedesco, F Veglia, AR Bonfigli, F Olivieri, A Raucci
Int J Mol Sci, 2020-06-23;21(12):.
Species: Human
Sample Types: Cell Culture Supernates
-
TLR3 expression by maternal and fetal cells at the maternal-fetal interface in normal and preeclamptic pregnancies
Authors: LM Gierman, GB Silva, Z Pervaiz, JJ Rakner, SB Mundal, AJ Thaning, I Nervik, M Elschot, S Mathew, LCV Thomsen, L Bjørge, AC Iversen
J. Leukoc. Biol., 2020-06-23;0(0):.
Species: Human
Sample Types: Placental Supernates
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Data describing expression of formyl peptide receptor 2 in human articular chondrocytes
Authors: A Strid Holm, CA Jonsson, M Mohaddes, C Lundqvist, H Forsman, I Gjertsson, K Önnheim
Data Brief, 2020-06-16;31(0):105866.
Species: Human
Sample Types: Cell Culture Supernates
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OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion
Authors: T O'Loughlin, AJ Kruppa, ALR Ribeiro, JR Edgar, A Ghannam, AM Smith, F Buss
J. Cell. Sci., 2020-06-15;0(0):.
Species: Human
Sample Types: Tissue Culture Supernates
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Root Extracts From Ononis spinosa Inhibit IL-8 Release via Interactions With Toll-Like Receptor 4 and Lipopolysaccharide
Authors: V Spiegler, B Gierlikows, T Saenger, JN Addotey, J Sendker, J Jose, AK Kiss, A Hensel
Front Pharmacol, 2020-06-12;11(0):889.
Species: Human
Sample Types: Cell Culture Supernates
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Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells
Authors: R Nallathamb, A Poulev, JB Zuk, I Raskin
Nutrients, 2020-06-01;12(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs of Elaeagnusrhamnoides (L.) A. Nelson-The Implications for Human Barrier Cells
Authors: B Sadowska, J Rywaniak, A Cichocka, K Cichocka, J ?uchowski, U Wójcik-Boj, M Wi?ckowska, B Ró?alska
Molecules, 2020-05-09;25(9):.
Species: Human
Sample Types: Cell Culture Supernates
-
N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
Nat Commun, 2020-05-05;11(1):2212.
Species: Human
Sample Types: Cell Culture Supernates
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Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses
Authors: L Mercurio, CM Failla, L Capriotti, C Scarponi, F Facchiano, M Morelli, S Rossi, G Pagnanelli, C Albanesi, A Cavani, S Madonna
PLoS ONE, 2020-04-30;15(4):e0222969.
Species: Human
Sample Types: Cell Culture Supernates
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Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
Authors: FJ Ryan, AM Ahern, RS Fitzgerald, EJ Laserna-Me, EM Power, AG Clooney, KW O'Donoghue, PJ McMurdie, S Iwai, A Crits-Chri, D Sheehan, C Moran, B Flemer, AL Zomer, A Fanning, J O'Callagha, J Walton, A Temko, W Stack, L Jackson, SA Joyce, S Melgar, TZ DeSantis, JT Bell, F Shanahan, MJ Claesson
Nat Commun, 2020-03-23;11(1):1512.
Species: Human
Sample Types: Cell Culture Supernates
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Diet influences the functions of the human intestinal microbiome
Authors: M De Angelis, I Ferrocino, FM Calabrese, F De Filippi, N Cavallo, S Siragusa, S Rampelli, R Di Cagno, K Rantsiou, L Vannini, N Pellegrini, C Lazzi, S Turroni, N Lorusso, M Ventura, M Chieppa, E Neviani, P Brigidi, PW O'Toole, D Ercolini, M Gobbetti, L Cocolin
Sci Rep, 2020-03-06;10(1):4247.
Species: Human
Sample Types: Cell Culture Supernates
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Ibrutinib induces multiple functional defects in the neutrophil response against Aspergillus fumigatus
Authors: D Blez, M Blaize, C Soussain, A Boissonnas, A Meghraoui-, N Menezes, A Portalier, C Combadière, V Leblond, D Ghez, A Fekkar
Haematologica, 2020-01-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Anti-CD3 Antibody Treatment Reduces Scar Formation in a Rat Model of Myocardial Infarction
Authors: B Wernly, V Paar, A Aigner, PM Pilz, BK Podesser, M Förster, C Jung, JP Hofbauer, B Tockner, M Wimmer, T Kraus, LJ Motloch, M Hackl, UC Hoppe, A Kiss, M Lichtenaue
Cells, 2020-01-25;9(2):.
Species: Human
Sample Types: Cell Culture Supernates
-
The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
Authors: T Furukawa, N van Rhijn, M Fraczek, F Gsaller, E Davies, P Carr, S Gago, R Fortune-Gr, S Rahman, JM Gilsenan, E Houlder, CH Kowalski, S Raj, S Paul, P Cook, JE Parker, S Kelly, RA Cramer, JP Latgé, S Moye-Rowle, E Bignell, P Bowyer, MJ Bromley
Nat Commun, 2020-01-22;11(1):427.
Species: Human
Sample Types: Cell Culture Supernates
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Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
Authors: I Gomez, B Ward, C Souilhol, C Recarti, M Ariaans, J Johnston, A Burnett, M Mahmoud, LA Luong, L West, M Long, S Parry, R Woods, C Hulston, B Benedikter, C Niespolo, R Bazaz, S Francis, E Kiss-Toth, M van Zandvo, A Schober, P Hellewell, PC Evans, V Ridger
Nat Commun, 2020-01-10;11(1):214.
Species: Human
Sample Types: Cell Culture Supernates
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Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes
Authors: R Riise, L Odqvist, J Mattsson, S Monkley, SM Abdillahi, C Tyrchan, D Muthas, LF Yrlid
Sci Rep, 2019-12-31;9(1):20407.
Species: Human
Sample Types: Cell Culture Supernates
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FOXO3a regulates rhinovirus-induced innate immune responses in airway epithelial cells
Authors: J Gimenes-Ju, N Owuar, HR Vari, W Li, N Xander, S Kotnala, US Sajjan
Sci Rep, 2019-12-03;9(1):18180.
Species: Human
Sample Types: Cell Culture Supernates
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C13 Megastigmane Derivatives From Epipremnum pinnatum: beta-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-kappaB Signaling
Authors: SP Pan, T Pirker, O Kunert, N Kretschmer, S Hummelbrun, SL Latkolik, J Rappai, VM Dirsch, V Bochkov, R Bauer
Front Pharmacol, 2019-11-28;10(0):1351.
Species: Human
Sample Types: Cell Culture Supernates
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LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD
Authors: J Knobloch, D Jungck, J Kronsbein, E Stoelben, K Ito, A Koch
J Clin Med, 2019-11-22;8(12):.
Species: Human
Sample Types: Cell Culture Supernates
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Replication of Genome-Wide Association Analysis Identifies New Susceptibility Loci at Long Noncoding RNA Regions for Vogt-Koyanagi-Harada Disease
Authors: J Qi, L Du, J Deng, Y Qin, G Su, S Hou, M Lv, Q Zhang, A Kijlstra, P Yang
Invest. Ophthalmol. Vis. Sci., 2019-11-01;60(14):4820-4829.
Species: Human
Sample Types: Cell Culture Supernates
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Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium
Authors: RF Hoffmann, MR Jonker, SM Brandenbur, HG de Bruin, NHT Ten Hacken, AJM van Ooster, IH Heijink
Sci Rep, 2019-10-21;9(1):15047.
Species: Human
Sample Types: Cell Culture Supernates
-
Disrupting prolonged sitting reduces IL-8 and lower leg swell in active young adults
Authors: S Dogra, M Wolf, MP Jeffrey, RCA Foley, H Logan-Spre, H Jones-Tagg, JM Green-John
BMC Sports Sci Med Rehabil, 2019-10-18;11(0):23.
Species: Human
Sample Types: Saliva
-
ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12
Authors: L Kloss, C Dollt, K Schledzews, A Krewer, S Melchers, C Manta, C Sticht, C Torre, J Utikal, V Umansky, A Schmieder
Cell Death Dis, 2019-10-07;10(10):760.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin
Authors: I Tsilioni, AB Patel, H Pantazopou, S Berretta, P Conti, SE Leeman, TC Theoharide
Proc. Natl. Acad. Sci. U.S.A., 2019-10-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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6-Shogaol Suppresses 2-Amino-1-Methyl-6-Phenylimidazo [4,5-b] Pyridine (PhIP)-Induced Human 786-O Renal Cell Carcinoma Osteoclastogenic Activity and Metastatic Potential
Authors: IJ Yeh, SC Chen, MC Yen, YH Wu, CH Hung, PL Kuo
Nutrients, 2019-09-28;11(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
Ouabain signaling in oral squamous cell carcinoma cells
Authors: S Saito, M Ohtsu, M Asano, T Ishigami
J Oral Sci, 2019-09-20;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression
Authors: Q Xu, Q Long, D Zhu, D Fu, B Zhang, L Han, M Qian, J Guo, J Xu, L Cao, YE Chin, JP Coppé, EW Lam, J Campisi, Y Sun
Aging Cell, 2019-09-07;0(0):e13027.
Species: Human
Sample Types: Serum
-
Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma
Authors: J Qiao, EJ Rellinger, KW Kim, CM Powers, S Lee, H Correa, DH Chung
Oncotarget, 2019-08-20;10(49):5028-5040.
Species: Human
Sample Types: Cell Culture Supernates
-
Microinvasion by Streptococcus pneumoniae induces epithelial innate immunity during colonisation at the human mucosal surface
Authors: CM Weight, C Venturini, S Pojar, SP Jochems, J Reiné, E Nikolaou, C Solórzano, M Noursadegh, JS Brown, DM Ferreira, RS Heyderman
Nat Commun, 2019-07-16;10(1):3060.
Species: Human
Sample Types: Cell Culture Supernates
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Interleukin 1 Receptor-Like 1 (IL1RL1) Promotes Airway Bacterial and Viral Infection and Inflammation
Authors: N Schaunaman, A Sanchez, KG Dimasuay, N Pavelka, M Numata, R Alam, RJ Martin, HW Chu
Infect. Immun., 2019-06-20;87(7):.
Species: Human
Sample Types: Cell Culture Supernates
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Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence
Authors: H Fleury, N Malaquin, V Tu, S Gilbert, A Martinez, MA Olivier, A Sauriol, L Communal, K Leclerc-De, E Carmona, D Provencher, AM Mes-Masson, F Rodier
Nat Commun, 2019-06-11;10(1):2556.
Species: Human
Sample Types: Cell Culture Supernates
-
The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis
Authors: P Dimou, RD Wright, KL Budge, A Midgley, SC Satchell, M Peak, MW Beresford
Sci Rep, 2019-06-06;9(1):8348.
Species: Human
Sample Types: Cell Culture Supernates
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A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer
Authors: M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek
Cancers (Basel), 2019-05-13;11(5):.
Species: Human
Sample Types: Cell Culture Supernates
-
Flagellin-independent effects of a Toll-like receptor 5 polymorphism in the inflammatory response to Burkholderia pseudomallei
Authors: AK Dickey, N Chantratit, S Tandhavana, D Ducken, L Lovelace-M, S Seal, J Robertson, ND Myers, S Schwarz, MM Wurfel, S Kosamo, TE West
PLoS Negl Trop Dis, 2019-05-08;13(5):e0007354.
Species: Human
Sample Types: Cell Culture Supernates
-
Intrapulmonary Autoantibodies to HSP72 Are Associated with Improved Outcomes in IPF
Authors: R Mills, A Mathur, LM Nicol, JJ Walker, AA Przybylski, AC Mackinnon, SEM Howie, WAH Wallace, I Dransfield, N Hirani
J Immunol Res, 2019-04-11;2019(0):1845128.
Species: Human
Sample Types: Cell Culture Supernates
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Activation of a TLR9 mediated innate immune response in preeclampsia
Authors: RD Williamson, FP McCarthy, LC Kenny, CM McCarthy
Sci Rep, 2019-04-11;9(1):5920.
Species: Human
Sample Types: Plasma
-
Evaluating S. flexneri pathogenesis in the human enteroid model
Authors: S Ranganatha, M Doucet, CL Grassel, B Delaine-El, NC Zachos, EM Barry
Infect. Immun., 2019-03-25;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation
Authors: C Harris, SD Thorpe, S Rushwan, W Wang, CL Thompson, JL Peacock, MM Knight, B Gooptu, A Greenough
J Biomech, 2019-03-22;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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The contraceptive medroxyprogesterone acetate, unlike norethisterone, directly increases R5 HIV-1 infection in human cervical explant tissue at physiologically relevant concentrations
Authors: RM Ray, MF Maritz, C Avenant, M Tomasicchi, S Dlamini, Z van der Sp, JP Hapgood
Sci Rep, 2019-03-13;9(1):4334.
Species: Human
Sample Types: Tissue Culture Supernates
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R. nukuhivensis acts by reinforcing skin barrier function, boosting skin immunity and by inhibiting IL-22 induced keratinocyte hyperproliferation
Authors: F Abdallah, G Lecellier, P Raharivelo, C Pichon
Sci Rep, 2019-03-11;9(1):4132.
Species: Human
Sample Types: Cell Culture Supernates
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?-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY
Authors: JC Sierra, G Suarez, MB Piazuelo, PB Luis, DR Baker, J Romero-Gal, DP Barry, C Schneider, DR Morgan, RM Peek, AP Gobert, KT Wilson
Proc. Natl. Acad. Sci. U.S.A., 2019-02-25;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes
Authors: CR Ojha, M Rodriguez, MKM Karuppan, J Lapierre, F Kashanchi, N El-Hage
PLoS ONE, 2019-02-08;14(2):e0208543.
Species: Human
Sample Types: Cell Culture Supernates
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Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5
Authors: S Giuliano, M Dufies, PD Ndiaye, J Viotti, D Borchielli, J Parola, V Vial, Y Cormerais, M Ohanna, V Imbert, E Chamorey, N Rioux-Lecl, A Savina, JM Ferrero, B Mograbi, G Pagès
Theranostics, 2019-01-30;9(4):1181-1199.
Species: Human
Sample Types: Cell Culture Supernates
-
Budesonide, Aclidinium and Formoterol in combination limit inflammaging processes in bronchial epithelial cells exposed to cigarette smoke
Authors: M Ferraro, S Di Vincenz, P Dino, S Bucchieri, C Cipollina, M Gjomarkaj, E Pace
Exp. Gerontol., 2019-01-16;118(0):78-87.
Species: Human
Sample Types: Cell Culture Supernates
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Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection
Authors: D Emal, E Rampanelli, N Claessen, FJ Bemelman, JC Leemans, S Florquin, MC Dessing
Sci Rep, 2019-01-14;9(1):106.
Species: Human
Sample Types: Cell Culture Supernates
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Neutrophil recruitment to inflamed joints can occur without cellular priming
Authors: L Björkman, K Christenso, L Davidsson, J Mårtensson, F Amirbeagi, A Welin, H Forsman, A Karlsson, C Dahlgren, J Bylund
J. Leukoc. Biol., 2018-12-20;0(0):.
Species: Human
Sample Types: Cell Lysates
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Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection
Authors: V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini
PLoS Pathog., 2018-12-07;14(12):e1007469.
Species: Human
Sample Types: Cell Culture Supernates
-
Copy number variations and founder effect underlying complete IL-10R? deficiency in Portuguese kindreds
Authors: F Charbit-He, B Bègue, A Sierra, S Hanein, MC Stolzenber, Z Li, S Pellegrini, N Garcelon, M Jeanpierre, B Neven, I Loge, C Picard, J Rosain, J Bustamante, M Le Lorc'h, B Pigneur, A Fernandes, F Rieux-Lauc, J Amil Dias, FM Ruemmele, N Cerf-Bensu
PLoS ONE, 2018-10-26;13(10):e0205826.
Species: Human
Sample Types: Cell Culture Supernates
-
Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance
Authors: F Chen, Q Long, D Fu, D Zhu, Y Ji, L Han, B Zhang, Q Xu, B Liu, Y Li, S Wu, C Yang, M Qian, J Xu, S Liu, L Cao, YE Chin, EW Lam, JP Coppé, Y Sun
Nat Commun, 2018-10-17;9(1):4315.
Species: Human
Sample Types: Serum
-
Human Mesenchymal Stem Cell Secretome from Bone Marrow or Adipose-Derived Tissue Sources for Treatment of Hypoxia-Induced Pulmonary Epithelial Injury
Authors: N Shologu, M Scully, JG Laffey, D O'Toole
Int J Mol Sci, 2018-09-30;19(10):.
Species: Human
Sample Types: Cell Culture Supernates
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Differential bronchial epithelial response regulated by ?Np63: a functional understanding of the epithelial shedding found in asthma
Authors: T Kubo, M Tsujiwaki, Y Hirohashi, T Tsukahara, T Kanaseki, M Nakatsugaw, T Hasegawa, T Torigoe
Lab. Invest., 2018-09-25;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
Biol. Reprod., 2018-09-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Serum from patients with chronic obstructive pulmonary disease induces senescence-related phenotype in bronchial epithelial cells
Authors: B Ku?nar-Kam, J Miku?a-Pie, A Witucka, A Romaniuk, N Konieczna, B Rubi?, K Ksi??ek, A Tykarski, H Batura-Gab
Sci Rep, 2018-08-28;8(1):12940.
Species: Human
Sample Types: Cell Culture Supernates
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IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
Authors: AC Gross, H Cam, DA Phelps, AJ Saraf, HK Bid, M Cam, CA London, SA Winget, MA Arnold, L Brandolini, X Mo, JM Hinckley, PJ Houghton, RD Roberts
JCI Insight, 2018-08-23;3(16):.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
Authors: SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali
Nat Commun, 2018-08-15;9(1):3267.
Species: Human
Sample Types: Cell Culture Supernates
-
Anti-inflammatory activity of CKC-containing cationic emulsion eye drop vehicles
Authors: P Daull, S Guenin, V Hamon de A, JS Garrigue
Mol. Vis., 2018-07-20;24(0):459-470.
Species: Human
Sample Types: Cell Culture Supernates
-
PGL I expression in live bacteria allows activation of a CD206/PPAR? cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral nerves
Authors: CC Díaz Acost, AA Dias, TLSA Rosa, LR Batista-Si, PS Rosa, TG Toledo-Pin, FDMR Costa, FA Lara, LS Rodrigues, KA Mattos, EN Sarno, PT Bozza, C Guilhot, M de Berrêdo, MCV Pessolani
PLoS Pathog., 2018-07-06;14(7):e1007151.
Species: Human
Sample Types: Cell Culture Supernates
-
Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages
Authors: RA Mubarak, N Roberts, RJ Mason, S Alper, HW Chu
Respir. Res., 2018-06-25;19(1):126.
Species: Human
Sample Types: Cell Culture Supernates
-
Genome wide analysis of TLR1/2- and TLR4-activated SZ95 sebocytes reveals a complex immune-competence and identifies serum amyloid A as a marker for activated sebaceous glands
Authors: D Tör?csik, D Kovács, S Póliska, Z Szentkeres, M Lovászi, K Hegyi, A Szegedi, CC Zouboulis, M Ståhle
PLoS ONE, 2018-06-21;13(6):e0198323.
Species: Human
Sample Types: Cell Culture Supernates
-
iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE
Authors: I Oikonomidi, E Burbridge, M Cavadas, G Sullivan, B Collis, H Naegele, D Clancy, J Brezinova, T Hu, A Bileck, C Gerner, A Bolado, A von Kriegs, SJ Martin, F Steinberg, K Strisovsky, C Adrain
Elife, 2018-06-13;7(0):.
Species: Human
Sample Types: Cell Culture Supernates
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Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations
Authors: JA Fraser, S Kemp, L Young, M Ross, M Prach, GR Hutchison, E Malone
Sci Rep, 2018-05-14;8(1):7506.
Species: Human
Sample Types: Cell Culture Supernates
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CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma
Authors: X Ye, X Wang, R Lu, J Zhang, X Chen, G Zhou
Oncol Lett, 2018-04-17;15(6):9075-9080.
Species: Human
Sample Types: Cell Culture Supernates
-
Age-Related Changes to Human Tear Composition
Authors: A Micera, A Di Zazzo, G Esposito, R Longo, W Foulsham, R Sacco, R Sgrulletta, S Bonini
Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2024-2031.
Species: Human
Sample Types: Tears
-
Effects of agricultural organic dusts on human lung-resident mesenchymal stem (stromal) cell function
Authors: TM Nordgren, KL Bailey, AJ Heires, D Katafiasz, DJ Romberger
Toxicol. Sci., 2018-04-01;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Variable localization of Toll-like receptors in human fallopian tube epithelial cells
Authors: F Amjadi, Z Zandieh, E Salehi, R Jafari, N Ghasemi, A Aflatoonia, A Fazeli, R Aflatoonia
Clin Exp Reprod Med, 2018-03-30;45(1):1-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Analysis of the association between Fc receptor family gene polymorphisms and ocular Beh�et's disease in Han Chinese
Authors: D Zhang, J Qin, L Li, G Su, G Huang, Q Cao, A Kijlstra, P Yang
Sci Rep, 2018-03-19;8(1):4850.
Species: Human
Sample Types: Cell Culture Supernates
-
Rhododendron album Blume extract inhibits TNF-?/IFN-?-induced chemokine production via blockade of NF-?B and JAK/STAT activation in human epidermal keratinocytes
Authors: JW Park, HS Lee, Y Lim, JH Paik, OK Kwon, JH Kim, I Paryanto, P Yunianto, S Choi, SR Oh, KS Ahn
Int. J. Mol. Med., 2018-03-09;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages
Authors: SR Lea, SL Reynolds, M Kaur, KD Simpson, SR Hall, EM Hessel, D Singh
Int J Chron Obstruct Pulmon Dis, 2018-03-02;13(0):771-780.
Species: Human
Sample Types: Cell Culture Supernates
-
Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD
Authors: Z Zeng, M Li, J Chen, Q Li, Q Ning, J Zhao, Y Xu, J Xie, J Yu
Int J Chron Obstruct Pulmon Dis, 2018-02-28;13(0):703-715.
Species: Human
Sample Types: Cell Culture Supernates
-
Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface
Authors: I Tomašek, CJ Horwell, C Bisig, DE Damby, P Comte, J Czerwinski, A Petri-Fink, MJD Clift, B Drasler, B Rothen-Rut
Environ. Pollut., 2018-02-16;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells
Authors: S Di Vincenz, IH Heijink, JA Noordhoek, C Cipollina, L Siena, A Bruno, M Ferraro, DS Postma, M Gjomarkaj, E Pace
J. Cell. Mol. Med., 2018-02-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Association of Long Noncoding RNAs Polymorphisms With Ankylosing Spondylitis, Vogt-Koyanagi-Harada Disease, and Behcet's Disease
Authors: Y Yue, J Zhang, L Yang, S Liu, J Qi, Q Cao, C Zhou, Y Wang, A Kijlstra, P Yang, S Hou
Invest. Ophthalmol. Vis. Sci., 2018-02-01;59(2):1158-1166.
Species: Human
Sample Types: Cell Culture Supernates
-
Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression
Authors: CC Wei, YJ Kung, CS Chen, CY Chang, CJ Lin, PT Tien, HY Chang, HJ Chen, YS Huang, HJ Lin, L Wan
EBioMedicine, 2018-01-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
Sci Rep, 2018-01-24;8(1):1561.
Species: Human
Sample Types: Cell Culture Supernates
-
Complement C5a Receptor 1 Exacerbates the Pathophysiology of N.�meningitidis Sepsis and Is a Potential Target for Disease Treatment
Authors: JB Herrmann, M Muensterma, L Strobel, A Schubert-U, TM Woodruff, SD Gray-Owen, A Klos, KO Johswich
MBio, 2018-01-23;9(1):.
Species: Human
Sample Types: Whole Blood
-
TiO2 nanoparticles can selectively bind CXCL8 impacting on neutrophil chemotaxis
Authors: J Batt, M Milward, I Chapple, M Grant, H Roberts, O Addison
Eur Cell Mater, 2018-01-19;35(0):13-24.
-
Bcl-3 induced by IL-22 via STAT3 activation acts as a potentiator of psoriasis-related gene expression in epidermal keratinocytes
Authors: M Tohyama, Y Shirakata, Y Hanakawa, X Dai, K Shiraishi, M Murakami, S Miyawaki, H Mori, R Utsunomiya, K Masuda, K Hashimoto, K Sayama
Eur. J. Immunol., 2017-11-20;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine
Authors: L Aubert, M Dubus, H Rammal, C Bour, C Mongaret, C Boulagnon-, R Garnotel, C Schneider, R Rahouadj, C Laurent, SC Gangloff, F Velard, C Mauprivez, H Kerdjoudj
Int J Mol Sci, 2017-10-21;18(10):.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-27 Modulates Chemokine Production in TNF-? -Stimulated Human Oral Epithelial Cells
Authors: Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo
Cell. Physiol. Biochem., 2017-10-05;43(3):1198-1206.
Species: Human
Sample Types: Cell Culture Supernates
-
The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors
Authors: J Miku?a-Pie, P Uruski, S Szubert, K Maksin, R Moszy?ski, D Szpurek, A Wo?niak, S Sajdak, A Tykarski, K Ksi??ek
Biomed Res Int, 2017-09-20;2017(0):2592496.
Species: Human
Sample Types: Cell Culture Supernates
-
Mild intracellular acidification by dexamethasone attenuates mitochondrial dysfunction in a human inflammatory proximal tubule epithelial cell model
Authors: TJJ Schirris, J Jansen, M Mihajlovic, LP van den He, R Masereeuw, FGM Russel
Sci Rep, 2017-09-06;7(1):10623.
Species: Human
Sample Types: Cell Culture Supernates
-
Increased expression of Siglec-9 in chronic obstructive pulmonary disease
Authors: Z Zeng, M Li, M Wang, X Wu, Q Li, Q Ning, J Zhao, Y Xu, J Xie
Sci Rep, 2017-08-31;7(1):10116.
Species: Human
Sample Types: Cell Culture Supernates
-
Activated Tissue-Resident Mesenchymal Stromal Cells Regulate Natural Killer Cell Immune and Tissue-Regenerative Function
Authors: RM Petri, A Hackel, K Hahnel, CA Dumitru, K Bruderek, SB Flohe, A Paschen, S Lang, S Brandau
Stem Cell Reports, 2017-08-03;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Allostimulatory capacity of conditionally immortalized proximal tubule cell lines for bioartificial kidney application
Authors: M Mihajlovic, LP van den He, JG Hoenderop, J Jansen, MJ Wilmer, AJF Westheim, WA Allebes, D Stamatiali, LB Hilbrands, R Masereeuw
Sci Rep, 2017-08-02;7(1):7103.
Species: Human
Sample Types: Cell Culture Supernates
-
Alpha1-antitrypsin binds hemin and prevents oxidative activation of human neutrophils: putative pathophysiological significance
Authors: S Janciauski, S Tumpara, M Wiese, S Wrenger, V Vijayan, F Gueler, R Chen, K Madyaningr, R Mahadeva, T Welte, S Immenschuh, J Chorostows
J. Leukoc. Biol., 2017-07-17;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
The Effect of a p38 Mitogen-Activated Protein Kinase Inhibitor on Cellular Senescence of Cultivated Human Corneal Endothelial Cells
Authors: A Hongo, N Okumura, M Nakahara, EP Kay, N Koizumi
Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3325-3334.
Species: Human
Sample Types: Cell Culture Supernates
-
The Role of Shed PrP(c) in the Neuropathogenesis of HIV Infection
Authors: BW Megra, EA Eugenin, JW Berman
J. Immunol., 2017-05-22;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways
Authors: A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, C Guguen-Gui
Sci Rep, 2017-05-12;7(1):1815.
Species: Human
Sample Types: Cell Culture Supernates
-
Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.
Authors: Lynne A Murray, Rebecca Dunmore, Ana Camelo, Carla A Da Silva, Malin J Gustavsso, David M Habiel, Tillie L Hackett, Cory M Hogaboam, Matthew A Sleeman, Darryl A Knight
Respiratory Research, 2017-05-03;0(0):1465-993X.
Species: Human
Sample Types: Cell Culture Supernates
-
Malaria pigment stimulates chemokine production by human microvascular endothelium
Authors: N Basilico, Y Corbett, S Alessandro, S Parapini, M Prato, D Girelli, P Misiano, P Olliaro, D Taramelli
Acta Trop., 2017-05-02;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression
Authors: A Ghosh, SH Abdelwahab, SL Reeber, B Reidel, AJ Marklew, AJ Garrison, S Lee, H Dang, AH Herring, GL Glish, M Kesimer, R Tarran
Sci Rep, 2017-04-27;7(0):46239.
Species: Human
Sample Types: Cell Culture Supernates
-
Experimental type 2 diabetes induction reduces serum vaspin, but not serum omentin, in Wistar rats
Authors: CA Castro, KA da Silva, MM Buffo, KNZ Pinto, FO Duarte, KO Nonaka, FF Aníbal, ACGO Duarte
Int J Exp Pathol, 2017-04-25;0(0):.
Species: Human
Sample Types: Serum
-
Methoxyluteolin Inhibits Neuropeptide-stimulated Proinflammatory Mediator Release via mTOR Activation from Human Mast Cells.
Authors: Patel A, Theoharides T
J Pharmacol Exp Ther, 2017-04-12;361(3):462-471.
Species: Human
Sample Types: Cell Culture Supernates
-
Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors
Authors: AH Bryant, GE Menzies, LM Scott, S Spencer-Ha, LB Davies, RA Smith, RH Jones, CA Thornton
Clin. Exp. Immunol, 2017-03-31;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Frequency and clinical significance of short cervix in patients with preterm premature rupture of membranes
Authors: SM Lee, KH Park, EY Jung, JA Jang, HN Yoo
PLoS ONE, 2017-03-30;12(3):e0174657.
Species: Human
Sample Types: Amniotic Fluid
-
Vitamin D both facilitates and attenuates the cellular response to lipopolysaccharide
Authors: L Chen, MS Eapen, GR Zosky
Sci Rep, 2017-03-27;7(0):45172.
Species: Human
Sample Types: Cell Culture Supernates
-
The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?
Authors: YA Hayman, LR Sadofsky, JD Williamson, SP Hart, AH Morice
ERJ Open Res, 2017-03-20;3(1):.
Species: Human
Sample Types: Cell Culture Supernates
-
Clinical significance of histologic chorioamnionitis with a negative amniotic fluid culture in patients with preterm labor and premature membrane rupture
Authors: JW Park, KH Park, EY Jung
PLoS ONE, 2017-03-09;12(3):e0173312.
Species: Human
Sample Types: Amniotic Fluid
-
Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells
Authors: V Selvarani, S Roland, S Andy, H James
Virus Res, 2017-03-07;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Amniotic Fluid Infection, Cytokine Levels, and Mortality and Adverse Pulmonary, Intestinal, and Neurologic Outcomes in Infants at 32 Weeks' Gestation or Less
Authors: EY Jung, KH Park, BR Han, SH Cho, HN Yoo, J Lee
J. Korean Med. Sci, 2017-03-01;32(3):480-487.
Species: Human
Sample Types: Amniotic Fluid
-
Changes in peripheral immune cell numbers and functions in octogenarian walkers - an acute exercise study
Authors: KS van der Ge, Q Wang, TM Eijsvogels, HJ Koenen, I Joosten, E Brouwer, MT Hopman, JF Jacobs, AM Boots
Immun Ageing, 2017-02-22;14(0):5.
Species: Human
Sample Types: Cell Culture Supernates
-
Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation
Authors: CM Henry, SJ Martin
Mol. Cell, 2017-02-16;65(4):715-729.e5.
Species: Human
Sample Types: Cell Culture Supernates
-
The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
Authors: T Hartwig, A Montinaro, S von Karste, A Sevko, S Surinova, A Chakravart, L Taraborrel, P Draber, E Lafont, F Arce Varga, MA El-Bahrawy, SA Quezada, H Walczak
Mol. Cell, 2017-02-16;65(4):730-742.e5.
Species: Human
Sample Types: Cell Culture Supernates
-
Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study
Authors: A Granitzny, J Knebel, M Müller, A Braun, P Steinberg, C Dasenbrock, T Hansen
Toxicol Rep, 2017-02-12;4(0):89-103.
Species: Human
Sample Types: Cell Culture Supernates
-
Chlamydial Lipoproteins Stimulate Toll-Like Receptors 1/2 Mediated Inflammatory Responses through MyD88-Dependent Pathway
Authors: Y Wang, Q Liu, D Chen, J Guan, L Ma, G Zhong, H Shu, X Wu
Front Microbiol, 2017-01-26;8(0):78.
Species: Human
Sample Types: Cell Culture Supernates
-
Mitochondrial proteins NIP-SNAP-1 and -2 are a target for the immunomodulatory activity of clarithromycin, which involves NF-?B-mediated cytokine production
Authors: Soh Yamamoto
Biochem. Biophys. Res. Commun, 2016-12-18;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability
Sci Rep, 2016-12-15;6(0):39035.
Species: Human
Sample Types: Cell Culture Supernates
-
Combined exposure of diesel exhaust particles and respirable Soufri�re Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
Authors: Ines Tomašek
Part Fibre Toxicol, 2016-12-12;13(1):67.
Species: Human
Sample Types: Cell Culture Supernates
-
The Anti-inflammatory Effect of Alpha-1 Antitrypsin in Rhinovirus-infected Human Airway Epithelial Cells
Authors: D Jiang, R Berman, Q Wu, C Stevenson, HW Chu
J Clin Cell Immunol, 2016-12-05;7(6):.
Species: Human
Sample Types: Cell Culture Supernates
-
Impaired anti-inflammatory action of glucocorticoid in neutrophil from patients with steroid-resistant asthma
Respir. Res., 2016-11-16;17(1):153.
Species: Human
Sample Types: Cell Culture Supernates
-
Essential Oils from Ugandan Medicinal Plants: In Vitro Cytotoxicity and Effects on IL-1?-Induced Proinflammatory Mediators by Human Gingival Fibroblasts
Evid Based Complement Alternat Med, 2016-10-11;2016(0):5357689.
Species: Human
Sample Types: Cell Culture Supernates
-
Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating
J Control Release, 2016-09-26;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Acanthamoeba castellanii (Genotype T4) Stimulates the Production of Interleukin-10 as well as Pro-inflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells and Human Monocyte-Derived Macrophages
Infect Immun, 2016-09-19;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Skin Barrier Recovery by Protease-Activated Receptor-2 Antagonist Lobaric Acid
Authors: Jae Sung Hwang
Biomol Ther (Seoul), 2016-09-01;24(5):529-35.
Species: Human
Sample Types: Cell Culture Supernates
-
Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells
Sci Rep, 2016-09-01;6(0):32505.
Applications: ChIP -
IL-17 Promotes Neutrophil-Mediated Immunity by Activating Microvascular Pericytes and Not Endothelium
J Immunol, 2016-08-17;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
mRNA expression pattern of selected candidate genes differs in bovine oviductal epithelial cells in vitro compared with the in vivo state and during cell culture passages
Authors: S Danesh Mes, J Sharbati, R Einspanier, C Gabler
Reprod. Biol. Endocrinol, 2016-08-15;14(1):44.
Species: Bovine
Sample Types: Cell Culture Supernates
-
Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells
PLoS ONE, 2016-07-21;11(7):e0154102.
Species: Human
Sample Types: Cell Culture Supernates
-
Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome
PLoS ONE, 2016-07-14;11(7):e0158969.
Species: Human
Sample Types: Cell Culture Supernates
-
The MNK-1/eIF4E pathway as a new therapeutic pathway to target inflammation and remodelling in asthma
Cell Signal, 2016-07-11;28(10):1555-1562.
Species: Human
Sample Types: Cell Culture Supernates
-
Inflammatory and immunological profiles in patients with COPD: relationship with FEV 1 reversibility
Authors: Cleriston Farias Queiroz
J Bras Pneumol, 2016-07-01;42(4):241-247.
Species: Human
Sample Types: Serum
-
A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro
Authors: Brian G Oliver
Thorax, 2016-06-10;71(11):1039-1049.
Species: Human
Sample Types: Cell Culture Supernates
-
Engineering a 3D microfluidic culture platform for tumor-treating field application
Sci Rep, 2016-05-24;6(0):26584.
Species: Human
Sample Types: Cell Culture Supernates
-
Local host response following an intramammary challenge with Staphylococcus fleurettii and different strains of Staphylococcus chromogenes in dairy heifers
Authors: K Piccart, J Verbeke, A De Vissche, S Piepers, F Haesebrouc, S De Vlieghe
Vet. Res., 2016-05-12;47(1):56.
Species: Bovine
Sample Types: Milk
-
Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin
J Immunol, 2016-04-29;196(11):4681-91.
Species: Human
Sample Types: Cell Culture Supernates
-
Genetic polymorphisms of cell adhesion molecules in Behcet's disease in a Chinese Han population
Authors: M Zheng, L Zhang, H Yu, J Hu, Q Cao, G Huang, Y Huang, G Yuan, A Kijlstra, P Yang
Sci Rep, 2016-04-25;6(0):24974.
Species: Human
Sample Types: Cell Culture Supernates
-
CREB regulates TNF-?-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts
Authors: Y Koga, T Hisada, T Ishizuka, M Utsugi, A Ono, M Yatomi, Y Kamide, H Aoki-Saito, H Tsurumaki, K Dobashi, M Yamada
Allergol Int, 2016-04-22;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells
Authors: S Robert, T Gicquel, A Bodin, V Lagente, E Boichot
PLoS ONE, 2016-04-05;11(4):e0153118.
Species: Human
Sample Types: Cell Culture Supernates
-
Integrated microRNA and mRNA Signature Associated with the Transition from the Locally Confined to the Metastasized Clear Cell Renal Cell Carcinoma Exemplified by miR-146-5p.
Authors: Wotschofsky Z, Gummlich L, Liep J, Stephan C, Kilic E, Jung K, Billaud J, Meyer H
PLoS ONE, 2016-02-09;11(2):e0148746.
Species: Human
Sample Types: Cell Culture Supernates
-
C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
J Immunol, 2016-01-22;196(5):2319-26.
Species: Human
Sample Types: Cell Culture Supernates
-
Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis.
Authors: Healey G, Collier C, Griffin S, Schuberth H, Sandra O, Smith D, Mahan S, Dieuzy-Labaye I, Sheldon I
J Immunol, 2015-12-16;196(2):823-31.
Species: Bovine
Sample Types: Cell Culture Supernates
-
The LasB Elastase of Pseudomonas aeruginosa Acts in Concert with Alkaline Protease AprA To Prevent Flagellin-Mediated Immune Recognition.
Authors: Casilag F, Lorenz A, Krueger J, Klawonn F, Weiss S, Haussler S
Infect Immun, 2015-10-26;84(1):162-71.
Species: Human
Sample Types: Cell Culture Supernates
-
Neutrophil oxidative burst activates ATM to regulate cytokine production and apoptosis.
Authors: Harbort C, Soeiro-Pereira P, von Bernuth H, Kaindl A, Costa-Carvalho B, Condino-Neto A, Reichenbach J, Roesler J, Zychlinsky A, Amulic B
Blood, 2015-10-21;126(26):2842-51.
Species: Human
Sample Types: Cell Culture Supernates
-
In vitro progesterone modulation on bacterial endotoxin-induced production of IL-1beta, TNFalpha, IL-6, IL-8, IL-10, MIP-1alpha, and MMP-9 in pre-labor human term placenta.
Authors: Garcia-Ruiz G, Flores-Espinosa P, Preciado-Martinez E, Bermejo-Martinez L, Espejel-Nunez A, Estrada-Gutierrez G, Maida-Claros R, Flores-Pliego A, Zaga-Clavellina V
Reprod Biol Endocrinol, 2015-10-07;13(0):115.
Species: Human
Sample Types: Cell Culture Supernates
-
Transcriptomic Analyses of the Biological Effects of Airborne PM2.5 Exposure on Human Bronchial Epithelial Cells.
Authors: Zhou Z, Liu Y, Duan F, Qin M, Wu F, Sheng W, Yang L, Liu J, He K
PLoS ONE, 2015-09-18;10(9):e0138267.
Species: Human
Sample Types: Cell Culture Supernates
-
Dexamethasone induces apoptosis in pulmonary arterial smooth muscle cells.
Authors: Price L, Shao D, Meng C, Perros F, Garfield B, Zhu J, Montani D, Dorfmuller P, Humbert M, Adcock I, Wort S
Respir Res, 2015-09-18;16(0):114.
Species: Human
Sample Types: Cell Culture Supernates
-
Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
Eur J Immunol, 2015-08-17;45(10):2937-44.
Species: Human
Sample Types: Cell Culture Supernates
-
Effect of lipopolysaccharide on glucocorticoid receptor function in control nasal mucosa fibroblasts and in fibroblasts from patients with chronic rhinosinusitis with nasal polyps and asthma.
Authors: Fernandez-Bertolin L, Mullol J, Fuentes-Prado M, Roca-Ferrer J, Alobid I, Picado C, Pujols L
PLoS ONE, 2015-05-05;10(5):e0125443.
Species: Human
Sample Types: Cell Culture Supernates
-
Detection and characterisation of Lactobacillus spp. in the bovine uterus and their influence on bovine endometrial epithelial cells in vitro.
Authors: Gartner M, Bondzio A, Braun N, Jung M, Einspanier R, Gabler C
PLoS ONE, 2015-03-24;10(3):e0119793.
Species: Human
Sample Types: Cell Culture Supernates
-
Innate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
Authors: Fieber C, Janos M, Koestler T, Gratz N, Li X, Castiglia V, Aberle M, Sauert M, Wegner M, Alexopoulou L, Kirschning C, Chen Z, von Haeseler A, Kovarik P
PLoS ONE, 2015-03-10;10(3):e0119727.
Species: Human
Sample Types: Cell Culture Supernates
-
Amyloid precursor protein mediated changes in intestinal epithelial phenotype in vitro.
Authors: Puig K, Manocha G, Combs C
PLoS ONE, 2015-03-05;10(3):e0119534.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of hydrogen sulfide in paramyxovirus infections.
Authors: Li H, Ma Y, Escaffre O, Ivanciuc T, Komaravelli N, Kelley J, Coletta C, Szabo C, Rockx B, Garofalo R, Casola A
J Virol, 2015-03-04;89(10):5557-68.
Species: Human
Sample Types: Cell Culture Supernates
-
Exposure to diesel exhaust particle extracts (DEPe) impairs some polarization markers and functions of human macrophages through activation of AhR and Nrf2.
Authors: Jaguin M, Fardel O, Lecureur V
PLoS ONE, 2015-02-24;10(2):e0116560.
Species: Human
Sample Types: Cell Culture Supernates
-
BET bromodomains regulate transforming growth factor-beta-induced proliferation and cytokine release in asthmatic airway smooth muscle.
Authors: Perry M, Durham A, Austin P, Adcock I, Chung K
J Biol Chem, 2015-02-19;290(14):9111-21.
Species: Human
Sample Types: Cell Culture Supernates
-
Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
Cell Death Differ, 2015-01-23;22(8):1313-27.
Species: Human
Sample Types: Cell Culture Supernates
-
Sialylation of Helicobacter bizzozeronii lipopolysaccharides modulates Toll-like receptor (TLR) 2 mediated response.
Authors: Kondadi P, Revez J, Hanninen M, Rossi M
Vet Res, 2015-01-21;46(0):4.
Species: Human
Sample Types: Cell Culture Supernates
-
Neutrophil IL-1beta processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.
Authors: Karmakar M, Katsnelson M, Malak H, Greene N, Howell S, Hise A, Camilli A, Kadioglu A, Dubyak G, Pearlman E
J Immunol, 2015-01-21;194(4):1763-75.
Species: Human
Sample Types: Whole Cells
-
Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis.
Authors: Schupp J, Binder H, Jager B, Cillis G, Zissel G, Muller-Quernheim J, Prasse A
PLoS ONE, 2015-01-15;10(1):e0116775.
Species: Human
Sample Types: BALF
-
Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production.
Authors: Langjahr P, Diaz-Jimenez D, De la Fuente M, Rubio E, Golenbock D, Bronfman F, Quera R, Gonzalez M, Hermoso M
PLoS ONE, 2014-12-22;9(12):e104624.
Species: Human
Sample Types: Cell Culture Supernates
-
A gut microbial metabolite of linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, ameliorates intestinal epithelial barrier impairment partially via GPR40-MEK-ERK pathway.
Authors: Miyamoto J, Mizukure T, Park S, Kishino S, Kimura I, Hirano K, Bergamo P, Rossi M, Suzuki T, Arita M, Ogawa J, Tanabe S
J Biol Chem, 2014-12-10;290(5):2902-18.
Species: Human
Sample Types: Cell Culture Supernates
-
Integrin alphaDbeta2 (CD11d/CD18) is expressed by human circulating and tissue myeloid leukocytes and mediates inflammatory signaling.
Authors: Miyazaki Y, Vieira-de-Abreu A, Harris E, Shah A, Weyrich A, Castro-Faria-Neto H, Zimmerman G
PLoS ONE, 2014-11-21;9(11):e112770.
Species: Human
Sample Types: Cell Culture Supernates
-
Human intestinal epithelial cells respond to beta-glucans via Dectin-1 and Syk.
Authors: Cohen-Kedar S, Baram L, Elad H, Brazowski E, Guzner-Gur H, Dotan I
Eur J Immunol, 2014-10-27;44(12):3729-40.
Species: Human
Sample Types: Cell Culture Supernates
-
Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats.
Authors: Lin F, Hsiao F, Huang C, Shih C, Tsao N, Tsai C, Yang S, Chang N, Hung S, Lin Y
PLoS ONE, 2014-07-24;9(7):e102450.
Species: Human
Sample Types: Cell Culture Supernates
-
Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma.
Authors: Green B, Wiriyachaiporn S, Grainge C, Rogers G, Kehagia V, Lau L, Carroll M, Bruce K, Howarth P
PLoS ONE, 2014-06-23;9(6):e100645.
Species: Human
Sample Types: Sputum
-
Periapical fluid RANKL and IL-8 are differentially regulated in pulpitis and apical periodontitis.
Authors: Rechenberg D, Bostanci N, Zehnder M, Belibasakis G
Cytokine, 2014-06-14;69(1):116-9.
Species: Human
Sample Types: Tissue Secretion
-
Flagellin concentrations in expectorations from cystic fibrosis patients.
Authors: Balloy V, Thevenot G, Bienvenu T, Morand P, Corvol H, Clement A, Ramphal R, Hubert D, Chignard M
BMC Pulm Med, 2014-06-09;14(0):100.
Species: Human
Sample Types: Sputum
-
Kineret(R)/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection.
Authors: Labrousse D, Perret M, Hayez D, da Silva S, Badiou C, Couzon F, Bes M, Chavanet P, Lina G, Vandenesch F, Croisier-Bertin D, Henry T
PLoS ONE, 2014-06-06;9(6):e97546.
Species: Human
Sample Types: BALF
-
Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses.
Authors: Hanuszkiewicz A, Pittock P, Humphries F, Moll H, Rosales A, Molinaro A, Moynagh P, Lajoie G, Valvano M
J Biol Chem, 2014-05-19;289(27):19231-44.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of non-coding RNAs in maintaining primary airway smooth muscle cells.
Authors: Perry, Mark M, Tsitsiou, Eleni, Austin, Philip J, Lindsay, Mark A, Gibeon, David S, Adcock, Ian M, Chung, Kian Fan
Respir Res, 2014-05-16;15(0):58.
Species: Human
Sample Types: Cell Culture Supernates
-
Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1beta-stimulated production of chemokines and matrix-degrading enzymes in vitro.
Authors: Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borzi R, Meliconi R
PLoS ONE, 2014-05-12;9(5):e96925.
Species: Human
Sample Types: Cell Culture Supernates
-
A functional variant of PTPN22 confers risk for Vogt-Koyanagi-Harada syndrome but not for ankylosing spondylitis.
Authors: Zhang Q, Qi J, Hou S, DU L, Yu H, Cao Q, Zhou Y, Liao D, Kijlstra A, Yang P
PLoS ONE, 2014-05-09;9(5):e96943.
Species: Human
Sample Types: Cell Culture Supernates
-
Chinese herbal medicine suppresses invasion-promoting capacity of cancer-associated fibroblasts in pancreatic cancer.
Authors: Chen, Lianyu, Qu, Chao, Chen, Hao, Xu, Litao, Qi, Qi, Luo, Jianmin, Wang, Kun, Meng, Zhiqiang, Chen, Zhen, Wang, Peng, Liu, Luming
PLoS ONE, 2014-04-29;9(4):e96177.
Species: Human
Sample Types: Cell Culture Supernates
-
Sphingosine 1-phosphate (S1P) induced interleukin-8 (IL-8) release is mediated by S1P receptor 2 and nuclear factor kappaB in BEAS-2B cells.
Authors: O'Sullivan M, Hirota N, Martin J
PLoS ONE, 2014-04-17;9(4):e95566.
Species: Human
Sample Types: Cell Culture Supernates
-
The Toll-like receptor 4 polymorphism Asp299Gly but not Thr399Ile influences TLR4 signaling and function.
Authors: Long H, O'Connor B, Zemans R, Zhou X, Yang I, Schwartz D
PLoS ONE, 2014-04-02;9(4):e93550.
Species: Human
Sample Types: Cell Culture Supernates
-
TRAIL-R1 is a negative regulator of pro-inflammatory responses and modulates long-term sequelae resulting from Chlamydia trachomatis infections in humans.
Authors: Al-Kuhlani M, Rothschild J, Pal S, de la Maza L, Ouburg S, Morre S, Dean D, Ojcius D
PLoS ONE, 2014-04-02;9(4):e93939.
Species: Human
Sample Types: Cell Culture Supernates
-
Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors.
Authors: Reed, Daniel M, Foldes, Gabor, Gatheral, Timothy, Paschalaki, Koralia, Lendvai, Zsuzsann, Bagyura, Zsolt, Nemeth, Tamas, Skopal, Judit, Merkely, Bela, Telcian, Aurica G, Gogsadze, Leila, Edwards, Michael, Gough, Peter J, Bertin, John, Johnston, Sebastia, Harding, Sian E, Mitchell, Jane A
PLoS ONE, 2014-04-01;9(4):e91119.
Species: Human
Sample Types: Cell Culture Supernates
-
Roles for the mitogen-activated protein kinase (MAPK) phosphatase, DUSP1, in feedback control of inflammatory gene expression and repression by dexamethasone.
Authors: Shah S, King E, Chandrasekhar A, Newton R
J Biol Chem, 2014-04-01;289(19):13667-79.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells.
Authors: Tanabe T, Shimokawaji T, Kanoh S, Rubin B
Clin Exp Allergy, 2014-04-01;44(4):540-52.
Species: Human
Sample Types: Cell Culture Supernates
-
Inflammatory and cytotoxic effects of acrolein, nicotine, acetylaldehyde and cigarette smoke extract on human nasal epithelial cells.
Authors: Comer D, Elborn J, Ennis M
BMC Pulm Med, 2014-03-01;14(0):32.
Species: Human
Sample Types: Cell Culture Supernates
-
Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6.
Authors: Turner M, Cronin J, Healey G, Sheldon I
Endocrinology, 2014-01-17;155(4):1453-65.
Species: Bovine
Sample Types: Cell Culture Supernates
-
CD137 ligand signalling induces differentiation of primary acute myeloid leukaemia cells.
Authors: Cheng K, Wong S, Linn Y, Ho L, Chng W, Schwarz H
Br J Haematol, 2014-01-15;165(1):134-44.
Species: Human
Sample Types: Cell Culture Supernates
-
TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behcet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
Authors: Xiang Q, Chen L, Hou S, Fang J, Zhou Y, Bai L, Liu Y, Kijlstra A, Yang P
PLoS ONE, 2014-01-08;9(1):e84214.
Species: Human
Sample Types: Cell Culture Supernates
-
Activin A as a mediator of NK-dendritic cell functional interactions.
Authors: Seeger P, Bosisio D, Parolini S, Badolato R, Gismondi A, Santoni A, Sozzani S
J Immunol, 2014-01-06;192(3):1241-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Lipid-modifying enzymes in human tear fluid and corneal epithelial stress response.
Authors: Robciuc A, Rantamaki A, Jauhiainen M, Holopainen J
Invest Ophthalmol Vis Sci, 2014-01-02;55(1):16-24.
Species: Human
Sample Types: Cell Culture Supernates
-
Selective activation of human dendritic cells by OM-85 through a NF-kB and MAPK dependent pathway.
Authors: Parola C, Salogni L, Vaira X, Scutera S, Somma P, Salvi V, Musso T, Tabbia G, Bardessono M, Pasquali C, Mantovani A, Sozzani S, Bosisio D
PLoS ONE, 2013-12-30;8(12):e82867.
Species: Human
Sample Types: Cell Culture Supernates
-
Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo.
Authors: Shamis Y, Silva E, Hewitt K, Brudno Y, Levenberg S, Mooney D, Garlick J
PLoS ONE, 2013-12-30;8(12):e83755.
Species: Human
Sample Types: Cell Culture Supernates
-
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Authors: Dreymueller D, Martin C, Schumacher J, Groth E, Boehm J, Reiss L, Uhlig S, Ludwig A
J Immunol, 2013-12-16;192(2):722-31.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin-8 responses of multi-layer gingival epithelia to subgingival biofilms: role of the "red complex" species.
Authors: Belibasakis G, Thurnheer T, Bostanci N
PLoS ONE, 2013-12-10;8(12):e81581.
-
Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system.
Authors: Punsmann S, Liebers V, Lotz A, Bruning T, Raulf M
PLoS ONE, 2013-12-10;8(12):e82734.
Species: Human
Sample Types: Serum
-
A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity.
Authors: Houser J, Komarek J, Kostlanova N, Cioci G, Varrot A, Kerr S, Lahmann M, Balloy V, Fahy J, Chignard M, Imberty A, Wimmerova M
PLoS ONE, 2013-12-10;8(12):e83077.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer.
Authors: Kachroo P, Lee M, Zhang L, Baratelli F, Lee G, Srivastava M, Wang G, Walser T, Krysan K, Sharma S, Dubinett S, Lee J
J Exp Clin Cancer Res, 2013-11-25;32(0):97.
Species: Human
Sample Types: Cell Culture Supernates
-
Leptin enhances the secretion of interleukin (IL)-18, but not IL-1beta, from human monocytes via activation of caspase-1.
Authors: Jitprasertwong P, Jaedicke K, Nile C, Preshaw P, Taylor J
Cytokine, 2013-11-23;65(2):222-30.
Species: Human
Sample Types: Cell Culture Supernates
-
Effects of nitrous oxide on the production of cytokines and chemokines by the airway epithelium during anesthesia with sevoflurane and propofol.
Authors: Kumakura S, Yamaguchi K, Sugasawa Y, Murakami T, Kikuchi T, Inada E, Nagaoka I
Mol Med Rep, 2013-10-21;8(6):1643-8.
Species: Human
Sample Types: Epithelial Fluid
-
Human neutrophil peptide-1 (HNP-1): a new anti-leishmanial drug candidate.
Authors: Dabirian S, Taslimi Y, Zahedifard F, Gholami E, Doustdari F, Motamedirad M, Khatami S, Azadmanesh K, Nylen S, Rafati S
PLoS Negl Trop Dis, 2013-10-17;7(10):e2491.
Species: Human
Sample Types: Cell Culture Supernates
-
Decidual natural killer cell interactions with trophoblasts are impaired in pregnancies at increased risk of preeclampsia.
Authors: Wallace A, Host A, Whitley G, Cartwright J
Am J Pathol, 2013-10-06;183(6):1853-61.
Species: Human
Sample Types: Cell Culture Supernates
-
Lipopolysaccharide promotes contraction of uterine myocytes via activation of Rho/ROCK signaling pathways.
Authors: Hutchinson J, Rajagopal S, Yuan M, Norman J
FASEB J, 2013-09-27;28(1):94-105.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others?
Authors: Doble, Rosella, McDermott, Michael, Cesur, Ozlem, Stonehouse, Nicola J, Wittmann, Miriam
J Invest Dermatol, 2013-09-20;134(3):852-5.
Species: Human
Sample Types: Cell Culture Supernates
-
Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity.
Authors: Hakim A, Barnes P, Adcock I, Usmani O
FASEB J, 2013-08-09;27(11):4510-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Tumor necrosis factor receptor 1 associates with CD137 ligand and mediates its reverse signaling.
Authors: Moh M, Lorenzini P, Gullo C, Schwarz H
FASEB J, 2013-04-25;27(8):2957-66.
Species: Human
Sample Types: Cell Culture Supernates
-
1,25-dihydroxyvitamin D3 protects against macrophage-induced activation of NFkappaB and MAPK signalling and chemokine release in human adipocytes.
Authors: Ding C, Wilding J, Bing C
PLoS ONE, 2013-04-24;8(4):e61707.
Species: Human
Sample Types: Cell Culture Supernates
-
S100A12 suppresses pro-inflammatory, but not pro-thrombotic functions of serum amyloid A.
Authors: Chung Y, Goyette J, Tedla N, Hsu K, Geczy C
PLoS ONE, 2013-04-24;8(4):e62372.
Species: Human
Sample Types: Cell Culture Supernates
-
Human cytomegalovirus induces a biphasic inflammatory response in primary endothelial cells.
Authors: Jeffery H, Soderberg-Naucler C, Butler L
J Virol, 2013-03-27;87(11):6530-5.
Species: Human
Sample Types: Cell Culture Supernates
-
Tetra- and penta-acylated lipid A structures of Porphyromonas gingivalis LPS differentially activate TLR4-mediated NF-kappaB signal transduction cascade and immuno-inflammatory response in human gingival fibroblasts.
Authors: Herath T, Darveau R, Seneviratne C, Wang C, Wang Y, Jin L
PLoS ONE, 2013-03-12;8(3):e58496.
Species: Human
Sample Types: Cell Culture Supernates
-
MicroRNA-16 affects key functions of human endothelial progenitor cells.
Authors: Goretti E, Rolland-Turner M, Leonard F, Zhang L, Wagner D, Devaux Y
J Leukoc Biol, 2013-01-16;93(5):645-55.
Species: Human
Sample Types: Cell Culture Supernates
-
Age-related changes in expression and function of Toll-like receptors in human skin.
Authors: Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schoppl A, Tschachler E, Elbe-Burger A
Development, 2012-10-03;139(22):4210-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse.
J Neuroinflammation, 2012-08-18;9(0):203.
Species: Human
Sample Types: Cell Culture Supernates
-
Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2.
Authors: Robciuc A, Hyotylainen T, Jauhiainen M, Holopainen J
J Lipid Res, 2012-08-15;53(11):2286-95.
Species: Human
Sample Types: Cell Culture Supernates
-
A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).
Authors: Breshears L, Schlievert P, Peterson M
J Biol Chem, 2012-07-25;287(39):32578-87.
Species: Human
Sample Types: Cell Culture Supernates
-
Impact of vitamin D supplementation on markers of inflammation in adults with cystic fibrosis hospitalized for a pulmonary exacerbation.
Eur J Clin Nutr, 2012-07-18;66(9):1072-4.
Species: Human
Sample Types: Plasma
-
Milk Matters: Soluble Toll-Like Receptor 2 (sTLR2) in Breast Milk Significantly Inhibits HIV-1 Infection and Inflammation.
Authors: Henrick BM, Nag K, Yao XD
PLoS ONE, 2012-07-06;7(7):e40138.
Species: Human
Sample Types: Cell Culture Supernates
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Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C.
Authors: Drannik AG, Nag K, Yao XD, Henrick BM, Sallenave JM, Rosenthal KL
PLoS ONE, 2012-04-24;7(4):e35866.
Species: Human
Sample Types: Cell Culture Supernates
-
Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
PLoS ONE, 2012-04-18;7(4):e34965.
Species: Human
Sample Types: Cell Culture Supernates
-
Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
Authors: Suh HS, Choi N, Tarassishin L, Lee SC
PLoS ONE, 2012-04-11;7(4):e35115.
Species: Human
Sample Types: Cell Culture Supernates
-
Transglutaminase is essential for IgA nephropathy development acting through IgA receptors.
Authors: Berthelot L, Papista C, Maciel TT, Biarnes-Pelicot M, Tissandie E, Wang PH, Tamouza H, Jamin A, Bex-Coudrat J, Gestin A, Boumediene A, Arcos-Fajardo M, England P, Pillebout E, Walker F, Daugas E, Vrtosvnik F, Flamant M, Benhamou M, Cogne M, Moura IC, Monteiro RC
J. Exp. Med., 2012-03-26;209(4):793-806.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist.
Authors: van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, Van der Meer JW, Hao R, Kalabokis V, Dinarello CA
Proc. Natl. Acad. Sci. U.S.A., 2012-02-06;109(8):3001-5.
Species: Human
Sample Types: Cell Culture Supernates
-
The role of IL-33 and its receptor ST2 in human nasal epithelium with allergic rhinitis.
Authors: Kamekura R, Kojima T, Takano K, Go M, Sawada N, Himi T
Clin. Exp. Allergy, 2012-02-01;42(2):218-28.
Species: Human
Sample Types: Cell Culture Supernates
-
A novel p38-MAPK signaling axis modulates neutrophil biology in head and neck cancer.
Authors: Dumitru CA, Fechner MK, Hoffmann TK
J. Leukoc. Biol., 2012-01-18;91(4):591-8.
Species: Human
Sample Types: Cell Culture Supernates
-
Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
Mucosal Immunol, 2011-12-21;5(2):140-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Epidermal growth factor receptor reactivation induced by E-prostanoid-3 receptor- and tumor necrosis factor-alpha-converting enzyme-dependent feedback exaggerates interleukin-8 production in airway cancer (NCI-H292) cells.
Authors: Kim S, Lewis C, Nadel JA
Exp. Cell Res., 2011-09-07;317(18):2650-60.
Species: Human
Sample Types: Cell Culture Supernates
-
Inhibition of IL-32 activation by alpha-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.
Authors: Marcondes AM, Li X, Tabellini L, Bartenstein M, Kabacka J, Sale GE, Hansen JA, Dinarello CA, Deeg HJ
Blood, 2011-09-06;118(18):5031-9.
Species: Human
Sample Types: Cell Culture Supernates
-
Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways.
Authors: Vega-Carrascal I, Reeves EP, Niki T, Arikawa T, McNally P, O'Neill SJ, Hirashima M, McElvaney NG
J. Immunol., 2011-01-24;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients.
Authors: Neuenschwander LC, Bittencourt H, Ribeiro AF, Teixeira AL, Teixeira MM, Teixeira JC, Nobre V
Clinics (Sao Paulo), 2011-01-01;66(10):1699-705.
Species: Human
Sample Types: Plasma
-
Human uterine epithelial cell secretions regulate dendritic cell differentiation and responses to TLR ligands.
Authors: Ochiel DO, Ghosh M, Fahey JV
J. Leukoc. Biol., 2010-04-12;88(3):435-44.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis.
Authors: Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG
J. Immunol., 2009-12-21;184(3):1642-52.
Species: Human
Sample Types: Serum
-
Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex.
Authors: Chui JJ, Li MW, Di Girolamo N, Chang JH, McCluskey PJ, Wakefield D
Invest. Ophthalmol. Vis. Sci., 2009-12-17;51(5):2558-67.
Species: Human
Sample Types: Cell Culture Supernates
-
Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
Authors: Hawn TR, Scholes D, Wang H, Li SS, Stapleton AE, Janer M, Aderem A, Stamm WE, Zhao LP, Hooton TM
PLoS ONE, 2009-12-15;4(12):e8300.
Species: Human
Sample Types: Urine
-
Activation of platelets by Aspergillus fumigatus and potential role of platelets in the immunopathogenesis of Aspergillosis.
Authors: Rodland EK, Ueland T, Pedersen TM, Halvorsen B, Muller F, Aukrust P, Froland SS
Infect. Immun., 2009-12-14;78(3):1269-75.
Species: Human
Sample Types: Cell Culture Supernates
-
Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.
Authors: Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB
J. Immunol., 2009-11-04;183(11):6989-97.
Species: Human
Sample Types: Cell Culture Supernates
-
IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression.
Authors: Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, Tokumaru S, Okazaki H, Sayama K, Hashimoto K
Eur. J. Immunol., 2009-10-01;39(10):2779-88.
Species: Human
Sample Types: Cell Culture Supernates
-
Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder.
Authors: Brietzke E, Kauer-Sant'Anna M, Teixeira AL, Kapczinski F
Brain Behav. Immun., 2009-05-04;23(8):1079-82.
Species: Human
Sample Types: Serum
-
Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
Circulation, 2009-03-02;119(10):1424-32.
Species: Human
Sample Types: Cell Culture Supernates
-
Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
Authors: Hao Q, Wang L, Tang H
Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7.
Species: Human
Sample Types: Cell Culture Supernates
-
Carbon dioxide inhalation causes pulmonary inflammation.
Authors: Abolhassani M, Guais A, Chaumet-Riffaud P, Sasco AJ, Schwartz L
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-01-09;296(4):L657-65.
Species: Human
Sample Types: Cell Culture Supernates
-
Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
J. Allergy Clin. Immunol., 2008-12-03;123(1):179-86.
Species: Human
Sample Types: Cell Culture Supernates
-
Adenosine receptors in regulation of dendritic cell differentiation and function.
Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
Blood, 2008-06-17;112(5):1822-31.
Species: Human
Sample Types: Cell Culture Supernates
-
Inorganic arsenic activates reduced NADPH oxidase in human primary macrophages through a Rho kinase/p38 kinase pathway.
Authors: Lemarie A, Bourdonnay E, Morzadec C, Fardel O, Vernhet L
J. Immunol., 2008-05-01;180(9):6010-7.
Species: Human
Sample Types: Cell Culture Supernates
-
Fungal proteases induce Th2 polarization through limited dendritic cell maturation and reduced production of IL-12.
Authors: Lamhamedi-Cherradi SE, Martin RE, Ito T, Kheradmand F, Corry DB, Liu YJ, Moyle M
J. Immunol., 2008-05-01;180(9):6000-9.
Species: Human
Sample Types: Cell Culture Supernates
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Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes.
Authors: Weigert J, Neumeier M, Wanninger J, Wurm S, Kopp A, Schober F, Filarsky M, Schaffler A, Zeitoun M, Aslanidis C, Buechler C
FEBS Lett., 2008-04-28;582(12):1777-82.
Species: Human
Sample Types: Cell Culture Supernates
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Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
Authors: Spadaro M, Caorsi C, Ceruti P, Varadhachary A, Forni G, Pericle F, Giovarelli M
FASEB J., 2008-03-25;22(8):2747-57.
Species: Human
Sample Types: Cell Culture Supernates
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Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macrophages.
Authors: Birrell MA, Wong S, Catley MC, Belvisi MG
J. Cell. Physiol., 2008-01-01;214(1):27-37.
Species: Human
Sample Types: Cell Culture Supernates
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Respiratory effects of exposure to diesel traffic in persons with asthma.
Authors: McCreanor J, Cullinan P, Nieuwenhuijsen MJ, Stewart-Evans J, Malliarou E, Jarup L, Harrington R, Svartengren M, Han IK, Ohman-Strickland P, Chung KF, Zhang J
N. Engl. J. Med., 2007-12-06;357(23):2348-58.
Species: Human
Sample Types: Sputum
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Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
J. Clin. Invest., 2007-12-01;117(12):3664-3672.
Species: Human
Sample Types: Cell Culture Supernates
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Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
Authors: Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG
J. Biol. Chem., 2007-08-31;282(44):31882-90.
Species: Human
Sample Types: Cell Culture Supernates
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Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea.
Authors: Yamasaki K, Di Nardo A, Bardan A, Murakami M, Ohtake T, Coda A, Dorschner RA, Bonnart C, Descargues P, Hovnanian A, Morhenn VB, Gallo RL
Nat. Med., 2007-08-05;13(8):975-80.
Species: Human
Sample Types: Cell Culture Supernates
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Airway remodelling in children with cystic fibrosis.
Authors: Hilliard TN, Regamey N, Shute JK, Nicholson AG, Alton EW, Bush A, Davies JC
Thorax, 2007-05-25;62(12):1074-80.
Species: Human
Sample Types: BALF
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Enhanced IL-1beta-induced IL-8 production in cystic fibrosis lung epithelial cells is dependent of both mitogen-activated protein kinases and NF-kappaB signaling.
Authors: Muselet-Charlier C, Roque T, Boncoeur E, Chadelat K, Clement A, Jacquot J, Tabary O
Biochem. Biophys. Res. Commun., 2007-04-02;357(2):402-7.
Species: Human
Sample Types: Cell Culture Supernates
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Mesenchymal stem cells support migration, extracellular matrix invasion, proliferation, and survival of endothelial cells in vitro.
Authors: Potapova IA, Gaudette GR, Brink PR, Robinson RB, Rosen MR, Cohen IS, Doronin SV
Stem Cells, 2007-03-29;25(7):1761-8.
Species: Human
Sample Types: Cell Culture Supernates
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A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways.
Authors: Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL
Biochem. Pharmacol., 2007-03-12;73(12):1957-70.
Species: Human
Sample Types: Cell Culture Supernates
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The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
Authors: Sa SM, Valdez PA, Wu J
J. Immunol., 2007-02-15;178(4):2229-40.
Species: Human
Sample Types: Cell Culture Supernates
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Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact cultures.
Authors: Sawant KV, McMurray DN
Infect. Immun., 2007-02-05;75(4):1870-7.
Species: Guinea Pig
Sample Types: Cell Culture Supernates
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Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.
Authors: Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-10-13;292(2):L567-76.
Species: Human
Sample Types: Cell Culture Supernates
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Toll-like receptor 2, 3, and 4 expression and function in human airway smooth muscle.
Authors: Sukkar MB, Xie S, Khorasani NM, Kon OM, Stanbridge R, Issa R, Chung KF
J. Allergy Clin. Immunol., 2006-07-03;118(3):641-8.
Species: Human
Sample Types: Cell Culture Supernates
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Role of matrix metalloproteinases in the inflammatory response in human airway cell-based assays and in rodent models of airway disease.
Authors: Birrell MA, Wong S, Dekkak A, De Alba J, Haj-Yahia S, Belvisi MG
J. Pharmacol. Exp. Ther., 2006-05-11;318(2):741-50.
Species: Human
Sample Types: Cell Culture Supernates
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Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
J. Immunol., 2006-03-15;176(6):3742-52.
Species: Human
Sample Types: Cell Culture Supernates
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Development of a guinea pig immune response-related microarray and its use to define the host response following Mycobacterium bovis BCG vaccination.
Authors: Tree JA, Elmore MJ, Javed S, Williams A, Marsh PD
Infect. Immun., 2006-02-01;74(2):1436-41.
Species: Guinea Pig
Sample Types: Cell Culture Supernates
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Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists.
Authors: Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M
Eur. J. Immunol., 2005-08-01;35(8):2459-70.
Species: Human
Sample Types: Cell Culture Supernates
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NF-kappaB in tracheal lavage fluid from intubated premature infants: association with inflammation, oxygen, and outcome.
Authors: Bourbia A, Cruz MA, Rozycki HJ
Arch. Dis. Child. Fetal Neonatal Ed., 2005-07-27;91(1):F36-9.
Species: Human
Sample Types: Tracheal Lavage Fluid
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IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate.
Authors: Miranda-Carus ME, Balsa A, Benito-Miguel M, Perez de Ayala C, Martin-Mola E
J. Immunol., 2004-07-15;173(2):1463-76.
Species: Human
Sample Types: Cell Culture Supernates
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Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
Blood, 2004-03-25;104(2):314-20.
Species: Human
Sample Types: Cell Culture Supernates
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Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk.
Authors: LeBouder E, Rey-Nores J, Rushmere N, Grigorov M, Lawn S, Affolter M, Griffin G, Ferrara P, Schiffrin E, Morgan B, Labeta M
J Immunol, 2003-12-15;171(12):6680-9.
Species: Human
Sample Types: Cell Culture Supernates
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Urinary interleukin-8 predicts the response of standard and low dose intravesical bacillus Calmette-Guerin (modified Danish 1331 strain) for superficial bladder cancer.
Authors: Kumar A, Dubey D, Bansal P, Mandhani A, Naik S
J. Urol., 2002-11-01;168(5):2232-5.
Species: Human
Sample Types: Urine
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Mycobacterium bovis BCG vaccination augments interleukin-8 mRNA expression and protein production in guinea pig alveolar macrophages infected with Mycobacterium tuberculosis.
Authors: Lyons MJ, Yoshimura T, McMurray DN
Infect. Immun., 2002-10-01;70(10):5471-8.
Species: Guinea Pig
Sample Types: Cell Culture Supernates
FAQs
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Is PBS a suitable alternative with which to formulate the Reagent Diluent?
Our lab has determined that Tris-buffered saline generates optimal assay performance in comparison to PBS for this assay. This assay is validated with Reagent Diluent formulated using Tris-buffered saline.
Reviews for Human IL-8/CXCL8 DuoSet ELISA
Average Rating: 4.7 (Based on 26 Reviews)
Have you used Human IL-8/CXCL8 DuoSet ELISA?
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Good results in plasma. Used neat and 1:5.
We used this kit for the quantification of IL-8 in human serum and plasma. We could not see any signals. Nevertheless, well-explained protocol.
Total Cell Protein
I would recommend using R&D's ancillary kit reagents.
Very nice IL8 detection in HUVEC cells treated with pro-inflammatory stimuli. Slightly higher background in untreated cells than expected, but not overly problematic. Would definitely publish and use again.