Human CXCR4 Fluorescein-conjugated Antibody Summary
Accession # P61073
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of CXCR4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 Fluorescein-conjugated Monoclonal Antibody (Catalog # FAB170F) and Mouse Anti-Human CD19 PE-conjugated Monoclonal Antibody (Catalog # FAB4867P). View our protocol for Staining Membrane-associated Proteins.
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Detection of CXCR4 in Jurkat vs K562 cells by Flow Cytometry Jurkat (filled histogram) vs K562 (open histogram) cells were stained with Mouse Anti-Human CXCR4 Fluorescein‑conjugated Monoclonal Antibody (Catalog # FAB170F). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CXCR4
CXCR4, also known as CD184, is a G-protein-linked seven transmembrane spanning receptor that binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor for T-cell tropic HIV-1 and -2 viral entry into cells.
Product Datasheets
Citations for Human CXCR4 Fluorescein-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
12
Citations: Showing 1 - 10
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Dysregulated megakaryocyte distribution associated with nestin+ mesenchymal stem cells in immune thrombocytopenia
Authors: Min Wang, Ru Feng, Jia-min Zhang, Lin-lin Xu, Fei-er Feng, Chen-cong Wang et al.
Blood Advances
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Natural Killer Cells from Allergic Donors Are Defective in Their Response to CCL18 Chemokine
Authors: L Amniai, C Ple, M Barrier, P de Nadai, P Marquillie, H Vorng, C Chenivesse, A Tsicopoulo, C Duez
International Journal of Molecular Sciences, 2021-04-09;22(8):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Glatiramer Acetate, Dimethyl Fumarate, and Monomethyl Fumarate Upregulate the Expression of CCR10 on the Surface of Natural Killer Cells and Enhance Their Chemotaxis and Cytotoxicity
Authors: Zaidoon Al-Jaderi
Front Immunol, 2016-10-19;7(0):437.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The role of SDF-1-CXCR4/CXCR7 axis in biological behaviors of adipose tissue-derived mesenchymal stem cells in vitro.
Authors: Li Q, Zhang A, Tao C, Li X, Jin P
Biochem Biophys Res Commun, 2013-10-30;441(3):675-80.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Identification of human NK17/NK1 cells.
Authors: Pandya AD, Al-Jaderi Z, Hoglund RA, Holmoy T, Harbo HF, Norgauer J, Maghazachi AA
PLoS ONE, 2011-10-21;6(10):e26780.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
Authors: Bosco MC, Pierobon D, Blengio F, Raggi F, Vanni C, Gattorno M, Eva A, Novelli F, Cappello P, Giovarelli M, Varesio L
Blood, 2010-12-10;117(9):2625-39.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Pathogen induction of CXCR4/TLR2 cross-talk impairs host defense function.
Authors: Hajishengallis G, Wang M, Liang S, Triantafilou M, Triantafilou K
Proc. Natl. Acad. Sci. U.S.A., 2008-09-02;105(36):13532-7.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Chemokine receptor expression on allergen-specific T cells in asthma and allergic bronchopulmonary aspergillosis.
Authors: Garcia G, Humbert M, Capel F, Rimaniol AC, Escourrou P, Emilie D, Godot V
Allergy, 2007-02-01;62(2):170-7.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
Immunology, 2004-06-01;112(2):274-89.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells.
Authors: Howard OM, Dong HF, Yang D, Raben N, Nagaraju K, Rosen A, Casciola-Rosen L, Hartlein M, Kron M, Yiadom K, Dwivedi S, Plotz PH, Oppenheim JJ
J. Exp. Med., 2002-09-16;196(6):781-91.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Expression and functional activity of CXCR-4 and CCR-5 chemokine receptors in human thymocytes.
Authors: Zamarchi R, 2019, Allavena P, Borsetti A, Stievano L, Tosello V, Marcato N, Esposito G, Roni V, Paganin C, Bianchi G, Titti F, Verani P, Gerosa G, Amadori A
192, 2002-02-01;127(2):321-30.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Downregulation of CXCR4 by SDF-KDEL in SBC-5 cells inhibits their migration in vitro and organ metastasis in vivo
Authors: NINGQIANG MA, HAILIN PANG, WEIWEI SHEN, FENG ZHANG, ZAOXUN CUI, JUNYAN WANG et al.
International Journal of Molecular Medicine
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