Human GPR18 (NP_005283) VersaClone cDNA

Catalog #: RDC0305 Datasheet / COA / SDS

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RDC0305

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Human GPR18 (NP_005283) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: GPR18

GPR18, the most abundantly overexpressed orphan GPCR in all melanoma metastases, is constitutively active and inhibits apoptosis, indicating an important role for GPR18 in tumor cell survival. GPR18 is expressed significantly in lymphoid cell lines, but not in non-lymphoid hematopoietic cell lines. N-arachidonylglycine (NAGly) induces an increase in intracellular Ca(2+) concentration in GPR18-transfected cells. GPR18 may be considered a potential novel anticancer target in metastatic melanoma.

Long Name

G Protein-coupled Receptor 18

Entrez Gene IDs

2841 (Human); 110168 (Mouse); 679957 (Rat)

Alternate Names

G protein-coupled receptor 18; GPCRW; GPR18; G-protein coupled receptor 18; NAGly Receptor; N-arachidonyl glycine receptor

Related Research Areas

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