Home / ICAM-3/CD50 / Human ICAM-3/CD50 FITC MAb (Clone Cal 3.10)

Human ICAM-3/CD50 FITC MAb (Clone Cal 3.10)

Catalog #: BBA35
13 Citations Datasheet / COA / SDS
Newer Version Available: BBA29
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Discontinued Product

BBA35 has been discontinued and is replaced by BBA29.

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Citations (13)
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Human ICAM-3/CD50 FITC MAb (Clone Cal 3.10) Summary

Species Reactivity
Human
Specificity

This antibody was found not to recognize CHO cells expressing either the human ICAM-1 protein or the human VCAM-1 protein. BBA 35 was found to recognize CHO cells expressing the human ICAM-3 protein. The epitope for BBA 35 has been found to be located on domain 1, or the interface of domains
1 and 2, of the human ICAM-3 molecule.

Source
Monoclonal Mouse IgG1 Clone # Cal 3.10 (2A5)
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: ICAM-3/CD50

Intercellular adhesion molecule 3 (ICAM-3), also known as CD50, is a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and alphad/beta2. ICAM-3 is expressed on leukocytes and epidermal Langerhans cells.

Long Name
Intercellular Adhesion Molecule 3
Entrez Gene IDs
3385 (Human)
Alternate Names
CD50 antigen; CD50; CDW50CDw50; ICAM3; ICAM-3; ICAM-Rintercellular adhesion molecule-3; intercellular adhesion molecule 3

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Citations for Human ICAM-3/CD50 FITC MAb (Clone Cal 3.10)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

13 Citations: Showing 1 - 10
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  1. Tumor necrosis factor-like weak inducer of apoptosis induces inflammation in Graves' orbital fibroblasts
    Authors: SJ Lee, J Kim, J Ko, EJ Lee, HJ Koh, JS Yoon
    PLoS ONE, 2018-12-21;13(12):e0209583.
  2. Human NK cells adapt their immune response towards increasing multiplicities of infection of Aspergillus fumigatus
    Authors: L Marischen, A Englert, AL Schmitt, H Einsele, J Loeffler
    BMC Immunol., 2018-12-18;19(1):39.
  3. Circulating levels of IL-1 family cytokines and receptors in Alzheimer's disease: new markers of disease progression?
    Authors: P Italiani, I Puxeddu, S Napoletano, E Scala, D Melillo, S Manocchio, A Angiolillo, P Migliorini, D Boraschi, E Vitale, A Di Costanz
    J Neuroinflammation, 2018-12-12;15(1):342.
  4. The Value of Older Donors' Klotho Level in Predicting Recipients' Short-Term Renal Function
    Authors: G Deng, A Yang, J Wu, J Zhou, S Meng, C Zhu, J Wang, S Shen, J Ma, D Liu
    Med. Sci. Monit., 2018-11-05;24(0):7936-7943.
  5. EphrinB/EphB forward signaling in M�ller cells causes apoptosis of retinal ganglion cells by increasing tumor necrosis factor alpha production in rat experimental glaucomatous model
    Authors: ST Liu, SM Zhong, XY Li, F Gao, F Li, ML Zhang, K Zhu, XH Sun, X Wang, Y Miao, XL Yang, Z Wang
    Acta Neuropathol Commun, 2018-10-24;6(1):111.
  6. The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes
    Authors: L Kasper, A König, PA Koenig, MS Gresnigt, J Westman, RA Drummond, MS Lionakis, O Gro beta, J Ruland, JR Naglik, B Hube
    Nat Commun, 2018-10-15;9(1):4260.
  7. Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells
    Authors: Y Otsuka, E Watanabe, E Shinya, S Okura, H Saeki, TBH Geijtenbee, H Takahashi
    J. Immunol., 2018-10-15;0(0):.
    Species: Human
    Sample Types:
  8. Different aspects of platelet evaluation in dengue: measurement of circulating mediators, ability to interact with the virus, the degree of activation and quantification of intraplatelet protein content
    Authors: TA da Costa B, D de Oliveir, AT de Carvalh, NR da Costa F, DF Barreto-Vi, F Cunha Jáco, OM Barth, RMR Nogueira, PC da Costa N, DC de Souza M, EL de Azeredo, PV Damasco, RV da Cunha, LM de-Oliveir
    Virus Res., 2018-09-30;0(0):.
  9. Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model
    Authors: GH Yang, C Zhang, N Wang, Y Meng, YS Wang
    Cytokine, 2018-09-28;111(0):350-356.
  10. Stevioside Prevents Wear Particle-Induced Osteolysis by Inhibiting Osteoclastogenesis and Inflammatory Response via the Suppression of TAK1 Activation
    Authors: J Meng, C Zhou, B Hu, M Luo, Y Yang, Y Wang, W Wang, G Jiang, J Hong, S Li, H Wu, S Yan, W Yan
    Front Pharmacol, 2018-09-26;9(0):1053.
  11. Systemic Inflammation Characterizes Lack of Metabolic Health in Nonobese HIV-Infected Men
    Authors: AN Monczor, X Li, FJ Palella, KM Erlandson, D Wiley, LA Kingsley, WS Post, LP Jacobson, TT Brown, JE Lake
    Mediators Inflamm., 2018-09-25;2018(0):5327361.
  12. Tandem CAR T cells targeting HER2 and IL13Ralpha2 mitigate tumor antigen escape.
    Authors: Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai S, Wakefield A, Fousek K, Bielamowicz K, Chow K, Brawley V, Byrd T, Krebs S, Gottschalk S, Wels W, Baker M, Dotti G, Mamonkin M, Brenner M, Orange J, Ahmed N
    J Clin Invest, 2016-07-18;126(8):3036-52.
  13. ICAM-3 influences human immunodeficiency virus type 1 replication in CD4(+) T cells independent of DC-SIGN-mediated transmission.
    Authors: Biggins JE, Biesinger T, Yu Kimata MT, Arora R, Kimata JT
    Virology, 2007-04-16;364(2):383-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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