Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Biotinylated Antibody

Name: Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Biotinylated Antibody
Brand: R&D Systems
SKU: FAB9718B
Price: 289 USD

Catalog #: FAB9718B Datasheet / COA / SDS

Recombinant Monoclonal Antibody For Research Use Only

Discontinued Product

FAB9718B has been discontinued.

View all IGF-I R/IGF1R products.

Detection of IGF-I R/IGF1R in MCF-7 human breast adenocarcinoma cell line by Flow Cytometry.

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All IGF-I R/IGF1R Antibodies

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Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human IGF-I R/IGF1R based on Teprotumumab therapeutic antibody. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Teprotumumab. This product is for research use only.

Source

Recombinant Monoclonal Human IgG₁ Clone # Hu14

Purification

Protein A or G purified from cell culture supernatant

Immunogen

Human IGF-I R/IGF1R

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Biotin

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

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Detection of IGF-I R/IGF1R in MCF-7 human breast adenocarcinoma cell line by Flow Cytometry. MCF-7 human breast adenocarcinoma cell line was stained with Human Anti-Human IGF-I R/IGF1R (Research Grade Teprotumumab Biosimilar) Biotinylated Monoclonal Antibody (Catalog # FAB9718B, filled histogram) or irrelevant biotinylated antibody (open histogram) followed by APC-conjugated Streptavidin (Catalog # F0050). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: IGF-I R/IGF1R

Teprotumumab is a biosimilar directed against the extracellular domain of IGF-I R/IGF1R. The biotinylated antibody can be used in flow cytometry or various assay format to measure IGF-I R/IGF1R expression and can be detected by conjugated streptavidin.

Long Name

Insulin-like Growth Factor I Receptor

Entrez Gene IDs

3480 (Human)

Alternate Names

CD221 antigen; CD221; EC 2.7.10; EC 2.7.10.1; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGF-IR; IGFR; insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; JTK13; MGC142170; MGC142172; MGC18216; soluble IGF1R variant 1; soluble IGF1R variant 2