Human Integrin beta 3/CD61 Antibody Summary
Gly27-Asp718
Accession # P05106
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of Integrin beta 3/CD61 in PBMC monocytes by Flow Cytometry PBMC monocytes were stained with Mouse Anti-Human CD14 APC‑conjugated Monoclonal Antibody (Catalog # FAB3832A) and either (A) Mouse Anti-Human Integrin beta 3/CD61 Monoclonal Antibody (Catalog # MAB2266) or (B) isotype control antibody (Catalog # MAB003) followed by Phycoerythrin-conjugated Anti-Mouse IgM Secondary Antibody (Catalog # F0116). View our protocol for Staining Membrane-associated Proteins.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Integrin beta 3/CD61
Integrin beta 3, also called CD61, associates with the Integrin alpha IIb or alpha V subunits to form heterodimeric receptors for collagens, fibronectin, vitronectin, fibrinogen, Von willebrand factor or thrombospondin. alpha IIb/ beta 3, also known as GPIIb IIIa (Glycoprotein IIb-IIIa), is expressed on platelets. alpha V/ beta 3, also known as vitronectin receptor, is expressed on endothelial cells, some B cells, platelets and monocytes.
Product Datasheets
Citations for Human Integrin beta 3/CD61 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma
Authors: H Odaka, K Hiemori, A Shimoda, K Akiyoshi, H Tateno
BMC gastroenterology, 2022-03-28;22(1):153.
Species: Human
Sample Types: Serum
Applications: ELISA Detection -
Platelet-derived extracellular vesicles are increased in sera of Alzheimer's disease patients, as revealed by Tim4-based assays
Authors: H Odaka, K Hiemori, A Shimoda, K Akiyoshi, H Tateno
FEBS Open Bio, 2021-02-03;0(0):.
Species: Human
Sample Types: Serum
Applications: ELISA Detection -
Delay of migrating leukocytes by the basement membrane deposited by endothelial cells in long-term culture.
Authors: Burton VJ, Butler LM, McGettrick HM, Stone PC, Jeffery HC, Savage CO, Rainger GE, Nash GB
Exp. Cell Res., 2010-11-04;317(3):276-92.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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