Human LAIR1 (NP_002278) VersaClone cDNA

Catalog #: RDC1883 Datasheet / COA / SDS

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RDC1883

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Human LAIR1 (NP_002278) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: LAIR1

LAIR proteins are related proteins that each contain one Ig-like domain and thus belong to the Ig superfamily. LAIR1 is a type I transmembrane protein with two cytoplasmic ITIM domains that functions as an inhibitory receptor on NK cells, T cells, B cells, monocytes, dendritic cells and most thymocytes. LAIR2 is a secreted protein with 83% amino acid identity to LAIR1 extracellular domain, but lacks the transmembrane and cytoplasmic domains. The function of LAIR2 is not known. Both LAIR1 and LAIR2 have alternately spliced isoforms.

Long Name

Leukocyte-associated Ig-like Receptor 1

Entrez Gene IDs

3903 (Human); 52855 (Mouse); 574531 (Rat); 102136964 (Cynomolgus Monkey)

Alternate Names

CD305 antigen; CD305; CD305leukocyte-associated Ig-like receptor 1; HLAIR1; LAIR1; LAIR-1; leukocyte-associated immunoglobulin-like receptor 1