Human Progesterone R/NR3C3 Antibody

Catalog #: PP-A9621A-00
2 Citations Datasheet / COA / SDS

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PP-A9621A-00

Product Details

Citations (2)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Progesterone R/NR3C3 Antibody Summary

Species Reactivity

Human

Specificity

This antibody specifically recognizes human PR isoform A and B and cross reacts with mouse and rat PR isoform A and B. Not yet tested in other species.

Source

Monoclonal Mouse IgG_2A Clone # A9621A

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

Recombinant human Progesterone R/NR3C3 Isoform A
aa 166-263

Formulation

A liquid formulation in physiologic saline with 0.1% NaN₃

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

This antibody can be used at 1 μg/mL under reducing andnon-reducing conditions with the appropriate secondary reagents to detecthuman PR.

Immunohistochemistry

This antibody can be used at 10 - 20 μg/mL withthe appropriate secondary reagents to detect human PR.

Immunoprecipitation

Optimal dilutions should be determined by eachlaboratory.

Direct ELISA

This antibody can be used at 10 ng/mL with the appropriatesecondary reagents to detect human PR.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: Progesterone R/NR3C3

Progesterone receptor (PR; NR3C3) is a member of the Steroid Receptor family. PR binds progesterone. PR is expressed in the uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with establishment and maintenance of pregnancy, alveolar development in the breast and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively.

Long Name

Progesterone Receptor

Entrez Gene IDs

5241 (Human)

Alternate Names

NR3C3; NR3C3PRNuclear receptor subfamily 3 group C member 3; PGR; Progesterone R; progesterone receptor; ProgesteroneR

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human Progesterone R/NR3C3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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