Human SOX17 Antibody Summary
Asp177-Val414
Accession # Q9H6I2
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
SOX17 in B16 Mouse Cell Line. SOX17 was detected in immersion fixed B16 mouse melanoma cell line using Mouse Anti-Human SOX17 Monoclonal Antibody (Catalog # MAB1924) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (yellow, upper panel; Catalog # NL007) and counterstained with DAPI (blue, lower panel). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SOX17
SOX17 is a member of the SOX family of transcription factors that bind DNA via a high mobility group (HMG) domain. SOX17 is suggested to play an important role in endoderm development (1, 2).
- Kanai-Azuma, M. et al. (2002) Development 129:2367.
- Katoh, M. et al. (2002) Int. J. Mol. Med. 9:153.
Product Datasheets
Citations for Human SOX17 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate
Authors: Sonia Stefanovic, Nesrine Abboud, Stéphanie Désilets, David Nury, Chad Cowan, Michel Pucéat
Journal of Cell Biology
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Differentiation of immortalized human multi-lineage progenitor to alveolar type 2-like cells: angiotensin-converting enzyme 2 expression and binding of severe acute respiratory syndrome coronavirus 2 spike and spike 1 proteins
Authors: Collins DP, Osborn MJ, Steer CJ. et al.
Cytotherapy
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Generation and characterization of integration-free induced pluripotent stem cells from patients with autoimmune disease
Authors: Mi-Young Son, Mi-Ok Lee, Hyejin Jeon, Binna Seol, Jung Hwa Kim, Jae-Suk Chang et al.
Experimental & Molecular Medicine
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Transplantation of Human Embryonic Stem Cell-Derived Pancreatic Endoderm Reveals a Site-Specific Survival, Growth, and Differentiation
Authors: Lina Sui, Josué K. Mfopou, Bing Chen, Karen Sermon, Luc Bouwens
Cell Transplantation
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Transcriptomic analysis of feeder-free culture system for maintaining naïve-state pluripotency in human pluripotent stem cells
Authors: Wataru Isono, Tomoyuki Kawasaki, Justin K. Ichida, Kazunori Nagasaka, Osamu Hiraike, Akihiro Umezawa et al.
Stem Cell Investigation
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In Vitro Modeling of Alcohol-Induced Liver Injury Using Human-Induced Pluripotent Stem Cells
Authors: Lipeng Tian, Neha Prasad, Yoon-Young Jang
Methods in Molecular Biology
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Indolactam V/GLP-1-mediated differentiation of human iPS cells into glucose-responsive insulin-secreting progeny
Authors: Tayaramma Thatava, Timothy J. Nelson, Ramakrishna Edukulla, Toshie Sakuma, Seiga Ohmine, Jason M. Tonne et al.
Gene Therapy
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Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation
Authors: Hogrebe, NJ;Schmidt, MD;Augsornworawat, P;Gale, SE;Shunkarova, M;Millman, JR;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation
Authors: Hernández, D;Morgan Schlicht, S;Elli Clarke, J;Daniszewski, M;Karch, CM;Dominantly Inherited Alzheimer Network (DIAN), ;Goate, AM;Pébay, A;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of induced pluripotent stem cell lines IRMBi003-A and IRMBi003-B from a healthy donor to model Alzheimer's disease
Authors: Clua Provost, C;Auboyer, L;Rovelet-Lecrux, A;Monzo, C;Schob, E;Andreux, F;Quittet, C;Lehmann, S;Wallon, D;Crozet, C;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry/ Immunofluorescence -
Establishment of induced pluripotent stem cells IRMBi005-A from a patient with sporadic Alzheimer's disease
Authors: Provost, CC;Auboyer, L;Rovelet-Lecrux, A;Monzo, C;Schob, E;Lehmann, S;Wallon, D;Crozet, C;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line XJHi001-A from a fibronectin glomerulopathy patient carrying a heterozygous NM_212482.2(C.5888-1G > C) mutation in the FN1 gene
Authors: She, L;Li, X;Bai, M;
Stem cell research
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC -
Large-scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal cross talk
Authors: Yu, L;Logsdon, D;Pinzon-Arteaga, CA;Duan, J;Ezashi, T;Wei, Y;Ribeiro Orsi, AE;Oura, S;Liu, L;Wang, L;Liu, K;Ding, X;Zhan, L;Zhang, J;Nahar, A;Stobbe, C;Katz-Jaffe, M;Schoolcraft, WB;Tan, T;Hon, GC;Yuan, Y;Wu, J;
Cell stem cell
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (ZSZOCi001-A) from a patient with Knobloch syndrome caused by biallelic mutations in the gene COL18A1
Authors: Jiang, Z;Sun, W;Zhang, Q;Wang, P;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human fibroblast-derived induced pluripotent stem cell line KRIBBi009-A from a patient with breast cancer
Authors: N Son, YS Son, CR Jung, MY Son
Stem Cell Research, 2023-03-14;68(0):103060.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Efficient reprogramming of human fibroblasts using RNA reprogramming with DAPT and iDOT1L under normoxia conditions
Authors: K Morita, A Nakamura, M Machida, T Kawasaki, R Nakanishi, J Ichida, T Iwata, A Umezawa, H Akutsu
Regenerative Therapy, 2022-09-19;21(0):389-397.
Species: Human
Sample Types: Organoid
Applications: IHC -
Generation of a human induced pluripotent stem cell line (LZUSHi002-A) from a MADD patient with ETFDH mutation
Authors: Y Li, Y Li, H Liu, L Cheng, H Ma, X Xu, N Zhang
Stem Cell Research, 2022-09-14;64(0):102914.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Generation of a homozygous knock-in human embryonic stem cell line expressing mEos4b-tagged CTR1
Authors: YH Chen, PS Huang, MH Wen, M Pan, DF Lee, TY Chen
Oncogene, 2022-06-14;63(0):102845.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an integration-free induced pluripotent stem cell line (LZUSHI001-A) from an epileptic patient with DGKG mutation
Authors: YQ Liu, TW Ling, HY Wang, YH Yang, WJ Song, TC Wang
Stem Cell Research, 2022-03-28;61(0):102768.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a gene corrected human isogenic iPSC line (CPGHi001-A-1) from a hearing loss patient with the TMC1 p.M418K mutation using CRISPR/Cas9
Authors: H Wang, Y Luo, J Li, J Guan, S Yang, Q Wang
Stem Cell Research, 2022-02-28;60(0):102736.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (FDCHI007-A) derived from a patient with developmental and epileptic encephalopathy Type 31 carrying heterozygous c.545C�>�A mutation in DNM1 gene
Authors: Y Xu, X Wang, T Qiu, J Wang, Y Wang, B Wu, Y Zhou
Stem Cell Research, 2022-02-12;60(0):102709.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer
Authors: L Lin, K Shi, S Zhou, MC Cai, C Zhang, Y Sun, J Zang, L Cheng, K Ye, P Ma, P Shen, M Zhang, Y Cheng, C Qi, Y Li, X Yin, Y Zheng, L Tan, G Zhuang, R Zang
Oncogene, 2022-02-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of human induced pluripotent stem cell line, KRIBBi003-A, from urinary cells of a patient with glycogen storage disease type IXa
Authors: Y Shin, SJ Mun, J Lee, KS Chung, M Kim, C Kun Cheon, MJ Son
Stem Cell Research, 2021-10-22;57(0):102584.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of an induced pluripotent stem cell line (FDCHi006-A) from a 7-year-old girl with central precocious puberty
Authors: T Fan, J He, Y Wang, J Yu, W Sun
Stem Cell Research, 2021-09-28;56(0):102542.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of insulin-producing pancreatic beta cells from multiple human stem cell lines
Authors: NJ Hogrebe, KG Maxwell, P Augsornwor, JR Millman
Nature Protocols, 2021-08-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of human induced pluripotent stem cell lines from 2 patients with MIRAGE syndrome
Authors: I Fischer, J Küchler, C Schaar, T Fisch, J Cernoch, K Fischer, V Fernández, P Kühnen, H Stachelsch
Stem Cell Research, 2021-06-10;54(0):102417.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an iPSC line (GWCMCi002-A) from an X-linked Alport syndrome patient with a hemizygous splicing mutation (NM_000495.4, c. 1517-1 G�>�T) in the COL4A5 gene
Authors: X Gao, G Li, H Deng, W Feng, Y Li, M Liu, Y Li
Stem Cell Research, 2021-05-11;53(0):102388.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line (CPGHi003-A) from an auditory neuropathy patient with AIFM1 p.R422Q mutation
Authors: J Li, K Wu, J Guan, Q Wang, H Wang
Stem Cell Research, 2021-04-29;53(0):102376.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an induced pluripotent stem cell line (OGHFUi001-A) from a type 1 early infantile epileptic encephalopathy with ARX mutation
Authors: N Jia, X Gong, J Chen, T Yang, C Bao, J Shen, X Xiao
Stem Cell Research, 2021-04-27;53(0):102367.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia
Authors: N Li, SM Lin, Y Li, J Sun, L Zhang, M Chen
Stem Cell Research, 2021-04-05;53(0):102322.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of a gene corrected human isogenic iPSC line (CPGHi002-A-1) from a DDOD patient with heterozygous c.1516 C>T mutation in the ATP6V1B2 gene
Authors: X Gao, SW Qiu, WQ Wang, DY Kang, N Su, P Dai, YY Yuan
Stem Cell Research, 2021-02-25;53(0):102271.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of a gene-corrected isogenic iPSC line (AHQUi001-A-1) from a patient with familial hypertriglyceridemia (FHTG) carrying a heterozygous p.C310R (c.928�T�>�C) mutation in LPL gene using CRISPR/Cas9
Authors: X Sun, X Zhou, B Dong, C Wang, X Xiao, Y Wang
Stem Cell Research, 2021-02-11;52(0):102230.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia
Authors: M Chen, SM Lin, N Li, Y Li, Y Li, L Zhang
Stem Cell Research, 2021-01-09;51(0):102166.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy
Authors: X Gao, X Liao, J Zhang, J Lin, M Tan
Stem Cell Research, 2020-12-10;50(0):102123.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an induced pluripotent stem cell line (PUMCHi006-A) derived from a patient with pulmonary arterial hypertension carrying heterozygous c.1339 G�>�A mutation in PTGIS gene
Authors: YJ Zhu, SJ Zhang, XH Wu, TY Lian, YZ He, ZJ Zhang, D Lu, K Sun, HF Wang, ZC Jing
Stem Cell Res, 2020-11-15;49(0):102088.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of gene-corrected iPSCs line (KEIUi001-A) from a PARK8 patient iPSCs with familial Parkinson's disease carrying the I2020T mutation in LRRK2
Authors: E Ohta, T Sone, H Ukai, T Hisamatsu, T Kitagawa, M Ishikawa, M Nagai, HR Ueda, F Obata, H Okano
Stem Cell Res, 2020-11-03;49(0):102073.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishment of human induced pluripotent stem cell line (CPGHi002-A) from a 10-month-old female patient with DDOD syndrome carrying a heterozygous c.1516 C�>�T mutation in ATP6V1B2
Authors: X Gao, SW Qiu, ML Feng, SS Huang, DY Kang, MY Han, P Dai, YY Yuan
Stem Cell Res, 2020-09-08;48(0):101986.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The combination of dibenzazepine and a DOT1L inhibitor enables a stable maintenance of human na�ve-state pluripotency in non-hypoxic conditions
Authors: W Isono, T Kawasaki, JK Ichida, T Ayabe, O Hiraike, A Umezawa, H Akutsu
Regenerative Therapy, 2020-09-02;15(0):161-168.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (CHFUi001-A) from an osteogenesis imperfecta patient with COL1A2 mutation
Authors: Z Zheng, W Lu, Z Pei, J Chen, T Yang, F Luo
Stem Cell Res, 2020-07-05;47(0):101907.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (SHEHi002-A (5426))from a patient of long QT syndrome type 8 with c.2573G>A mutation in the gene CACNA1C
Authors: HM Zhou, XQ Zhou, JZ Lu, WW Jia, JH Kang
Stem Cell Res, 2020-02-06;43(0):101731.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Measles vector as a multiple genes delivery platform facilitating iPSC reprogramming
Authors: Q Wang, A Vossen, Y Ikeda, P Devaux
Gene Ther., 2019-02-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two human isogenic iPSC lines from fetal dermal fibroblasts
Authors: R Tandon, B Brändl, N Baryshniko, A Landshamme, L Steenpa beta, O Keminer, O Pless, FJ Müller
Stem Cell Res, 2018-10-12;33(0):120-124.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells
Authors: L Yu, J Li, J Hong, Y Takashima, N Fujimoto, M Nakajima, A Yamamoto, X Dong, Y Dang, Y Hou, W Yang, I Minami, K Okita, M Tanaka, C Luo, F Tang, Y Chen, C Tang, H Kotera, L Liu
Stem Cell Reports, 2018-06-28;11(1):142-156.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line from a patient with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP): HIHCNi003-A
Authors: SN Hayer, Y Schelling, P Hoeflinger, S Hauser, L Schöls
Stem Cell Res, 2018-06-20;30(0):206-209.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
PI3K/mTORC2 regulates TGF-beta/Activin signalling by modulating Smad2/3 activity via linker phosphorylation.
Authors: Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, Cui W
Nat Commun, 2015-05-22;6(0):7212.
Species: Human
Sample Types: Cell Lysates, Whole Cells
Applications: IHC, Western Blot -
Intrapatient variations in type 1 diabetes-specific iPS cell differentiation into insulin-producing cells.
Authors: Thatava T, Kudva Y, Edukulla R, Squillace K, De Lamo J, Khan Y, Sakuma T, Ohmine S, Terzic A, Ikeda Y
Mol Ther, 2012-11-27;21(1):228-39.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, IHC-Fr -
FGF signaling via MAPK is required early and improves Activin A-induced definitive endoderm formation from human embryonic stem cells.
Authors: Sui L, Mfopou J, Geens M, Sermon K, Bouwens L
Biochem Biophys Res Commun, 2012-08-29;426(3):380-5.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
New cell lines from mouse epiblast share defining features with human embryonic stem cells.
Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
Nature, 2007-06-27;448(7150):196-9.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Conditional gene expression in human embryonic stem cells.
Authors: Vallier L, Alexander M, Pedersen R
Stem Cells, 2007-02-22;25(6):1490-7.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.
Authors: Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH
FEBS Lett., 2006-10-02;580(25):5869-74.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
Authors: Seiga Ohmine, Karen A. Squillace, Katherine A. Hartjes, Michael C. Deeds, Adam S. Armstrong, Tayaramma Thatava et al.
Aging (Albany NY)
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Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells
Authors: Rajagopal N Aravalli, Daniel P Collins, Joel H Hapke, Andrew T Crane, Clifford J Steer
Hepatic Medicine: Evidence and Research
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Engineering human hepato-biliary-pancreatic organoids from pluripotent stem cells
Authors: Hiroyuki Koike, Kentaro Iwasawa, Rie Ouchi, Mari Maezawa, Masaki Kimura, Asuka Kodaka et al.
Nature Protocols
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Induced pluripotent stem cells from GMP-grade hematopoietic progenitor cells and mononuclear myeloid cells
Authors: Seiga Ohmine, Allan B Dietz, Michael C Deeds, Katherine A Hartjes, David R Miller, Tayaramma Thatava et al.
Stem Cell Research & Therapy
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Effects of the Extracts from Fruit and Stem of Camellia japonica on Induced Pluripotency and Wound Healing
Authors: H Jeon, JY Kim, JK Choi, E Han, CL Song, J Lee, YS Cho
J Clin Med, 2018-11-20;7(11):.
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Changes in the hepatic differentiation potential of human mesenchymal stem cells aged in vitro
Authors: Sang Luo, Shuai Xiao, Yang Ai, Ben Wang, Yefu Wang
Annals of Translational Medicine
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Early gestation chorionic villi-derived stromal cells for fetal tissue engineering
Authors: Lee Lankford, Taryn Selby, James Becker, Volodymyr Ryzhuk, Connor Long, Diana Farmer et al.
World Journal of Stem Cells
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Intrinsic Immunity Shapes Viral Resistance of Stem Cells
Authors: Xianfang Wu, Viet Loan Dao Dao Thi, Yumin Huang, Eva Billerbeck, Debjani Saha, Hans-Heinrich Hoffmann et al.
Cell
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