Human STRO-1 Antibody Summary
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
STRO‑1 in Human MG‑63 Cell Line. STRO-1 was detected in immersion fixed MG-63 human osteosarcoma cell line using Human STRO-1 Monoclonal Antibody (Catalog # MAB1038) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgM Secondary Antibody (red; NL019), and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: STRO-1
STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units-fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells (1). The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes (2).
Product Datasheets
Citations for Human STRO-1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Osteogenic differentiation and inflammatory response of recombinant human bone morphogenetic protein‑2 in human maxillary sinus membrane‑derived cells
Authors: Jeewan Chun, Junho Jung, Jae-Hyung Lee, Sang-Hwan Oh, Yong-Dae Kwon
Experimental and Therapeutic Medicine
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Different concentrations of fetal bovine serum affect cytokine modulation in Lipopolysaccharide-activated apical papilla cells in vitro*
Authors: Letícia Martins SANTOS, Patricia e Silva CARDOSO, Elisa Abreu DINIZ, Juliana Garuba RAHHAL, Carla Renata SIPERT
Journal of Applied Oral Science
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Non-viral reprogramming of human Wharton's jelly cells reveals differences between ATOH1 homologues.
Authors: Mellott AJ, Devarajan K, Shinogle H et al.
Tissue Eng Part A.
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TGF beta signaling links early life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
Authors: Maria Victoria Bariani, Yan-Hong Cui, Mohamed Ali, Tao Bai, Sandra L. Grimm, Cristian Coarfa et al.
Cell Mol Life Sci
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Enzyme-free isolation of mesenchymal stem cells from decidua basalis of the human placenta
Authors: Srishti Dutta Gupta, Ankita Sen, Priyanshu Priyadarshi, Malancha Ta
STAR Protocols
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TGF? signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells
Authors: Bariani, MV;Cui, YH;Ali, M;Bai, T;Grimm, SL;Coarfa, C;Walker, CL;He, YY;Yang, Q;Al-Hendy, A;
Research square
Species: Rat
Sample Types: Whole Cells
Applications: Immunoprecipitation -
IPSC-Derived Sensory Neurons Directing Fate Commitment of Human BMSC-Derived Schwann Cells: Applications in Traumatic Neural Injuries
Authors: Tam, KW;Wong, CY;Wu, KL;Lam, G;Liang, X;Wong, WT;Li, MT;Liu, WY;Cai, S;Shea, GK;Shum, DK;Chan, YS;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Influence of Ascorbic Acid as a Growth and Differentiation Factor on Dental Stem Cells Used in Regenerative Endodontic Therapies
Authors: A Diederich, HJ Fründ, B Trojanowic, A Navarrete, AD Nguyen, C Hoang-Vu, CR Gernhardt
Journal of Clinical Medicine, 2023-02-02;12(3):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
A Clinical Study of Alveolar Bone Tissue Engineering Using Autologous Bone Marrow Stromal Cells: Effect of Optimized Cell-Processing Protocol on Efficacy
Authors: H Kagami, M Inoue, H Agata, I Asahina, T Nagamura-I, M Taguri, A Tojo
Journal of Clinical Medicine, 2022-12-09;11(24):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Enamel Matrix Derivative Enhances the Odontoblastic Differentiation of Dental Pulp Stem Cells via Activating MAPK Signaling Pathways
Authors: B Zhang, M Xiao, X Cheng, Y Bai, H Chen, Q Yu, L Qiu
Stem Cells International, 2022-04-28;2022(0):2236250.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Treated dentin matrix induces odontogenic differentiation of dental pulp stem cells via regulation of Wnt/beta-catenin signaling
Authors: S Liu, J Sun, S Yuan, Y Yang, Y Gong, Y Wang, R Guo, X Zhang, Y Liu, H Mi, M Wang, M Liu, R Li
Bioactive materials, 2021-06-05;7(0):85-97.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla
Authors: J Liang, YJ Zhao, JQ Li, L Lan, WJ Tao, JY Wu
Journal of dental sciences, 2021-04-24;17(1):264-275.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Cellular response of human apical papilla cells to calcium hydroxide and tricalcium silicate-based cements
Authors: M Garrido, D Morales, MP Saldías, C Fernández, V Villalobos, O Cerda, M Cáceres
BMC Oral Health, 2021-03-09;21(1):106.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Establishment and neural differentiation of neural crest-derived stem cells from human dental pulp in serum-free conditions
Authors: Oscar O. Solis-Castro, Fiona M. Boissonade, Marcelo N. Rivolta
Stem Cells Translational Medicine
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Altered Secretome and ROS Production in Olfactory Mucosa Stem Cells Derived from Friedreich’s Ataxia Patients
Authors: Sara Pérez-Luz, Frida Loria, Yurika Katsu-Jiménez, Daniel Oberdoerfer, Oscar-Li Yang, Filip Lim et al.
International Journal of Molecular Sciences
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R-Spondin 2 Induces Odontogenic Differentiation of Dental Pulp Stem/Progenitor Cells via Regulation of Wnt/beta-Catenin Signaling
Authors: Y Gong, S Yuan, J Sun, Y Wang, S Liu, R Guo, W Dong, R Li
Front Physiol, 2020-08-07;11(0):918.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Characterization of proliferation, differentiation potential, and gene expression among clonal cultures of human dental pulp cells
Authors: Tomoko Kobayashi, Daisuke Torii, Takanori Iwata, Yuichi Izumi, Masanori Nasu, Takeo W. Tsutsui
Human Cell
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EphrinB2 overexpression enhances osteogenic differentiation of dental pulp stem cells partially through ephrinB2-mediated reverse signaling
Authors: W Wang, C Yuan, T Geng, Y Liu, S Zhu, C Zhang, Z Liu, P Wang
Stem Cell Res Ther, 2020-01-29;11(1):40.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Deconstructed Microfluidic Bone Marrow On-A-Chip to Study Normal and Malignant Hemopoietic Cell-Niche Interactions
Authors: Aleman J, George SK, Herberg S et al.
Small
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A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1+/CD44+ Cells
Authors: Lauren E. Prusinski Fernung, Ayman Al-Hendy, Qiwei Yang
Reproductive Sciences
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Fluoxetine induces direct inhibitory effects on mesenchymal stem cell?derived osteoprogenitor cells independent of serotonin concentration
Authors: SM Koura, M Salama, M El-Hussiny, MEA Khalil, A Lotfy, SA Hassan, SA Gad Elhak, MA Sobh
Mol Med Rep, 2019-02-01;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Flow Cytometry -
Identifying deer antler uhrf1 proliferation and s100a10 mineralization genes using comparative RNA-seq
Authors: DFE Ker, D Wang, R Sharma, B Zhang, B Passarelli, N Neff, C Li, W Maloney, S Quake, YP Yang
Stem Cell Res Ther, 2018-10-31;9(1):292.
Species: Deer
Sample Types: Whole Cells
Applications: Flow Cytometry -
Safety and efficacy of the mesenchymal stem cell in feline eosinophilic keratitis treatment
Authors: AJ Villatoro, S Claros, V Fernández, C Alcoholado, F Fariñas, A Moreno, J Becerra, JA Andrades
BMC Vet. Res., 2018-03-27;14(1):116.
Species: Feline
Sample Types: Whole Cells
Applications: Flow Cytometry -
Evaluating Interaction of Cord Blood Hematopoietic Stem/Progenitor Cells with Functionally Integrated Three-Dimensional Microenvironments
Authors: S Mokhtari, PM Baptista, DA Vyas, CJ Freeman, E Moran, M Brovold, GA Llamazares, Z Lamar, CD Porada, S Soker, G Almeida-Po
Stem Cells Transl Med, 2018-02-23;7(3):271-282.
Species: Human
Sample Types: Whole Cells
Applications: Cell Selection -
Ganglioside GM1 contributes to extracellular/intracellular regulation of insulin resistance, impairment of insulin signaling and down-stream eNOS activation, in human aortic endothelial cells after short- or long-term exposure to TNF?
Authors: N Sasaki, Y Itakura, M Toyoda
Oncotarget, 2017-12-15;9(5):5562-5577.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
In-vitro characterization of canine multipotent stromal cells isolated from synovium, bone marrow, and adipose tissue: a donor-matched comparative study
Authors: RN Bearden, SS Huggins, KJ Cummings, R Smith, CA Gregory, WB Saunders
Stem Cell Res Ther, 2017-10-03;8(1):218.
Species: Canine
Sample Types: Whole Cells
Applications: Flow Cytometry -
Human Dental Pulp Cells Differentiate toward Neuronal Cells and Promote Neuroregeneration in Adult Organotypic Hippocampal Slices In Vitro
Authors: L Xiao, R Ide, C Saiki, Y Kumazawa, H Okamura
Int J Mol Sci, 2017-08-11;18(8):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
A monoclonal antibody recognizes undifferentiation-specific carbohydrate moieties expressed on cell surface of the human dental pulp cells
Authors: KJ Kang, SY Ko, CJ Ryu, YJ Jang
Stem Cell Res, 2017-04-06;21(0):85-93.
Species: Human
Sample Types: Tissue Homogenates
Applications: Flow Cytometry -
The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70
Stem Cells, 2017-01-23;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
In vivo experimental model of orthotopic dental pulp regeneration under the influence of photobiomodulation therapy
Authors: Maria Stella Moreira
J. Photochem. Photobiol. B, Biol, 2016-12-02;166(0):180-186.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC-P -
?-Catenin Accumulation Is Associated With Increased Expression of Nanog Protein and Predicts Maintenance of MSC Self-Renewal
Authors: SJ Yu, HJ Kim, ES Lee, CG Park, SJ Cho, SH Jeon
Cell Transplant, 2016-09-27;26(2):365-377.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The differentiation potential of gingival mesenchymal stem cells induced by apical tooth germ cell?conditioned medium
Mol Med Rep, 2016-09-06;14(4):3565-72.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Immobilized WNT Proteins Act as a Stem Cell Niche for Tissue Engineering
Stem Cell Reports, 2016-07-12;7(1):126-37.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Skeletal ligament healing using the recombinant human amelogenin protein
Authors: Salem Hanhan, Ayala Ejzenberg, Koby Goren, Faris Saba, Yarden Suki, Shay Sharon et al.
Journal of Cellular and Molecular Medicine
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Restoration of a Critical Mandibular Bone Defect Using Human Alveolar Bone-Derived Stem Cells and Porous Nano-HA/Collagen/PLA Scaffold
Authors: X Wang, H Xing, G Zhang, X Wu, X Zou, L Feng, D Wang, M Li, J Zhao, J Du, Y Lv, L E, H Liu
Stem Cells Int, 2016-03-28;2016(0):8741641.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Interferon-gamma improves impaired dentinogenic and immunosuppressive functions of irreversible pulpitis-derived human dental pulp stem cells.
Authors: Sonoda S, Yamaza H, Ma L, Tanaka Y, Tomoda E, Aijima R, Nonaka K, Kukita T, Shi S, Nishimura F, Yamaza T
Sci Rep, 2016-01-18;6(0):19286.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Kinetics of Label Retaining Cells in the Developing Rat Kidneys
Authors: Jianwen Wang, Guiting Lin, Amjad Alwaal, Xiaoyu Zhang, Guifang Wang, Xingyuan Jia et al.
PLOS ONE
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Derivation of Mesenchymal Stromal Cells from Canine Induced Pluripotent Stem Cells by Inhibition of the TGF beta /Activin Signaling Pathway
Authors: Deanne J. Whitworth, Jessica E. Frith, Thomas J.R. Frith, Dmitry A. Ovchinnikov, Justin J. Cooper-White, Ernst J. Wolvetang
Stem Cells and Development
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Wnts enhance neurotrophin-induced neuronal differentiation in adult bone-marrow-derived mesenchymal stem cells via canonical and noncanonical signaling pathways.
Authors: Tsai H, Deng W, Lai W, Chiu W, Yang C, Tsai Y, Hwang S, Renshaw P
PLoS ONE, 2014-08-29;9(8):e104937.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis.
Authors: Brady K, Dickinson S, Guillot P, Polak J, Blom A, Kafienah W, Hollander A
Stem Cells Dev, 2013-12-04;23(5):541-54.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mesenchymal stem cells engineered to inhibit complement-mediated damage.
Authors: Soland M, Bego M, Colletti E, Zanjani E, St Jeor S, Porada C, Almeida-Porada G
PLoS ONE, 2013-03-26;8(3):e60461.
Species: Human
Sample Types: Tissue Homogenates
Applications: Cell Selection -
A genomics approach in determining nanotopographical effects on MSC phenotype
Authors: Penelope M. Tsimbouri, Kate Murawski, Graham Hamilton, Pawel Herzyk, Richard O.C. Oreffo, Nikolaj Gadegaard et al.
Biomaterials
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Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis
Authors: Akihiko Hasegawa, Hiroyuki Nakahara, Mitsuo Kinoshita, Hiroshi Asahara, James Koziol, Martin K Lotz
Arthritis Research & Therapy
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In vitro proliferation and differentiation of adipose-derived stem cells isolated using anti-CD105 magnetic beads
Authors: XIAO-JIE LV, GUANG-DONG ZHOU, YANG LIU, XIA LIU, JUN-NAN CHEN, XU-SONG LUO et al.
International Journal of Molecular Medicine
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Intercellular transport of Oct4 in mammalian cells: a basic principle to expand a stem cell niche?
Authors: Rolf HJ, Niebert S, Niebert M, Gaus L, Schliephake H, Wiese KG
PLoS ONE, 2012-02-16;7(2):e32287.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Characterization of mesenchymal progenitor cells isolated from human bone marrow by negative selection.
Authors: Modder UI, Roforth MM, Nicks KM, Peterson JM, McCready LK, Monroe DG, Khosla S
Bone, 2011-12-28;50(3):804-10.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Pluripotency of mesenchymal cells derived from synovial fluid in patients with temporomandibular joint disorder
Authors: Noriaki Koyama, Yasunori Okubo, Kazumasa Nakao, Kenji Osawa, Kazuma Fujimura, Kazuhisa Bessho
Life Sciences
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Human Periosteum Is a Source of Cells for Orthopaedic Tissue Engineering: A Pilot Study
Authors: Michael D. Ball, Ian C. Bonzani, Melissa J. Bovis, Andrew Williams, Molly M. Stevens
Clinical Orthopaedics & Related Research
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High levels of beta-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway.
Authors: Liu N, Shi S, Deng M, Tang L, Zhang G, Liu N, Ding B, Liu W, Liu Y, Shi H, Liu L, Jin Y
J. Bone Miner. Res., 2011-09-01;26(9):2082-95.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Efficacy of Periodontal Stem Cell Transplantation in the Treatment of Advanced Periodontitis
Authors: Joo-Young Park, Soung Hoo Jeon, Pill-Hoon Choung
Cell Transplantation
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Synovial sarcoma is a stem cell malignancy.
Authors: Naka N, Takenaka S, Araki N
Stem Cells, 2010-07-01;28(7):1119-31.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Temporal Analysis of Equine Bone Marrow Aspirate During Establishment of Putative Mesenchymal Progenitor Cell Populations
Authors: Catherine H. Radcliffe, M. Julia B.F. Flaminio, Lisa A. Fortier
Stem Cells and Development
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Multipotent mesenchymal stem cells from human placenta: critical parameters for isolation and maintenance of stemness after isolation.
Authors: Semenov O, Koestenbauer S, Riegel M, Zech N, Zimmermann R, Zisch A, Malek A
Am J Obstet Gynecol, 2009-12-24;202(2):193.e1-193.e1.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Regeneration of bone and periodontal ligament induced by recombinant amelogenin after periodontitis
Authors: Amir Haze, Angela L. Taylor, Stefan Haegewald, Yoav Leiser, Boaz Shay, Eli Rosenfeld et al.
Journal of Cellular and Molecular Medicine
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Three-dimensional reconstituted extracellular matrix scaffolds for tissue engineering.
Authors: Narayanan K, Leck KJ, Gao S, Wan AC
Biomaterials, 2009-05-28;30(26):4309-17.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Stem cells from deciduous tooth repair mandibular defect in swine.
Authors: Zheng Y, Liu Y, Zhang CM
J. Dent. Res., 2009-03-01;88(3):249-54.
Species: Porcine
Sample Types: Whole Cells
Applications: ICC -
Investigating a clonal human periodontal ligament progenitor/stem cell line in vitro and in vivo.
Authors: Fujii S, Maeda H, Wada N, Tomokiyo A, Saito M, Akamine A
J. Cell. Physiol., 2008-06-01;215(3):743-9.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Promotion of attachment of human bone marrow stromal cells by CCN2.
Authors: Ono M, Kubota S, Fujisawa T, Sonoyama W, Kawaki H, Akiyama K, Oshima M, Nishida T, Yoshida Y, Suzuki K, Takigawa M, Kuboki T
Biochem. Biophys. Res. Commun., 2007-03-19;357(1):20-5.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Phenotypic and functional characteristics of mesenchymal stem cells differentiated along a Schwann cell lineage.
Authors: Caddick J, Kingham PJ, Gardiner NJ, Wiberg M, Terenghi G
Glia, 2006-12-01;54(8):840-9.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Isolation and characterization of a stem cell population from adult human liver.
Authors: Herrera MB, Bruno S, Buttiglieri S, Tetta C, Gatti S, Deregibus MC, Bussolati B, Camussi G
Stem Cells, 2006-08-31;24(12):2840-50.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Mechanical stress promotes the expression of smooth muscle-like properties in marrow stromal cells.
Authors: Kobayashi N, Yasu T, Ueba H, Sata M, Hashimoto S, Kuroki M, Saito M, Kawakami M
Exp. Hematol., 2004-12-01;32(12):1238-45.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Low-Density Lipoprotein Uptake Demonstrates a Hepatocyte Phenotype in the Dog, but Is Nonspecific.
Authors: Gow A, Muirhead R, Hay D, Argyle D
Stem Cells Dev, 2015-11-10;25(1):90-100.
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