Human TREML1/TLT-1 Biotinylated Antibody

Catalog #: BAF2394 Datasheet / COA / SDS

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BAF2394

All TREML1/TLT-1 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human TREML1/TLT-1 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects TREML1/TLT‑1 in Western blots. In Western blots, less than 2% cross-reactivity with recombinant mouse TLT-1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human TREML1
Gln16-Ser160 (predicted)
Accession # Q86YW5

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human TREML1/TLT‑1

Flow Cytometry

2.5 µg/10⁶ cells

Human platelets

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TREML1/TLT-1

TREML1 is a type I transmembrane protein that differs from TREM in the cytoplasmic region by having two ITIMs (Immunoreceptor Tyrosine-based Inhibition Motif). A splice variant lacking ITIMs in its cytoplasmic domain also exists. TREML1 is found only in platelets and megakaryocytes. The extracellular region of human and mouse TREML1 share 75% amino acid sequence identity.

Long Name

Triggering Receptor Expressed on Myeloid Cells-like 1

Entrez Gene IDs

340205 (Human); 71326 (Mouse)

Alternate Names

dJ238O23.3; GLTL1825; PRO3438; TLT1; TLT-1; TLT1MGC119173; TREML1; trem-like transcript 1 protein; triggering receptor expressed on myeloid cells-like 1; Triggering receptor expressed on myeloid cells-like protein 1