Human Tryptase alpha /TPS1 Biotinylated Antibody

Catalog #: BAF2370 Datasheet / COA / SDS

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BAF2370

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Human Tryptase alpha /TPS1 Biotinylated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Tryptase alpha /TPS1 in Western blots. In Western blots, approximately 60% cross-reactivity with recombinant human (rh) TPSB2 is observed and approximately 10% cross-reactivity with rhTPSG1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Tryptase alpha /TPS1
Ile31-Pro275
Accession # AAA86934

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human Tryptase alpha /TPS1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Tryptase alpha/TPS1

Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase beta-1, also known as mast cell protease 7 (MCPT7), exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. Tryptase epsilon, also known as brain-specific serine protease 4 (BSSP-4) and brain serine protease 2 (BSP-2), is encoded by the PRSS22 gene and preferentially expressed in epithelium-rich tissues such as lung and eye. Tryptase gamma-1, also called transmembrane tryptase, is encoded by TPSG1, one of many serine protease genes clustered on human chromosome 16p13.3.

Entrez Gene IDs

7177 (Human)

Alternate Names

alpha-Tryptase; EC:3.4.21.59; epididymis secretory sperm binding protein; mast cell alpha II tryptase; mast cell beta I tryptase; mast cell tryptase; TPS1; TPS2; TPSAB1; TPSB1; TPSB2; Tryptase 1; tryptase alpha II; Tryptase alpha; Tryptase alpha-1; tryptase beta I; tryptase beta-1; Tryptase beta-2; Tryptase I; tryptase II; tryptase-1; tryptase-2; tryptase-I; tryptase-III