Human VCAM-1/CD106 PE-conjugated Antibody

Catalog #: FAB5649P
9 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
FAB5649P

Detection of VCAM‑1/CD106 in HuT 78 Human Cell Line by Flow Cytometry.

1 Image

All VCAM-1/CD106 Antibodies

Product Details

Citations (9)

Supplemental Products

Reviews

Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human VCAM-1/CD106 PE-conjugated Antibody Summary

Species Reactivity

Human

Specificity

The antibody was screened using COS cells transfected with cDNAs for E-Selectin, VCAM-1, ICAM-1 and PECAM-1 and was shown to be specific for human VCAM-1/CD106.

Source

Monoclonal Mouse IgG_2A Clone # IE10

Purification

Protein A or G purified from ascites

Immunogen

Activated HUVEC human umbilical vein endothelial cells

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Label

Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration

Sample

Flow Cytometry

10 µL/10⁶ cells

See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry

View Larger

Detection of VCAM‑1/CD106 in HuT 78 Human Cell Line by Flow Cytometry. HuT 78 human cutaneous T cell lymphoma cell line was stained with Mouse Anti-Human VCAM-1/CD106 PE-conjugated Monoclonal Antibody (Catalog # FAB5649P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.

12 months from date of receipt, 2 to 8 °C as supplied.

Background: VCAM-1/CD106

Vascular cell adhesion molecule 1 (VCAM-1) is expressed on the surface of activated endothelial cells and macrophages. It binds to leukocyte integrins VLA-4 and alpha 4 beta 7 to promote leukocyte adhesion at sites of inflamed vasculature.

Long Name

Vascular Cell Adhesion Molecule 1

Entrez Gene IDs

7412 (Human); 22329 (Mouse)

Alternate Names

CD106 antigen; CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561; vascular cell adhesion molecule 1; vascular cell adhesion protein 1; V-CAM 1; VCAM1; VCAM-1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human VCAM-1/CD106 PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

9 Citations: Showing 1 - 9
Filter your results:

Filter by:

DC8 and DC13 var Genes Associated with Severe Malaria Bind Avidly to Diverse Endothelial Cells
Authors: Marion Avril, Andrew J. Brazier, Martin Melcher, Sowmya Sampath, Joseph D. Smith
PLoS Pathogens
ROS- and Radiation Source-Dependent Modulation of Leukocyte Adhesion to Primary Microvascular Endothelial Cells
Authors: D Eckert, F Rapp, AT Tsedeke, J Molendowsk, R Lehn, M Langhans, C Fournier, F Rödel, S Hehlgans
Cells, 2021-12-27;11(1):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Differences in Endothelial Activation and Dysfunction Induced by Antiphospholipid Antibodies Among Groups of Patients With Thrombotic, Refractory, and Non-refractory Antiphospholipid Syndrome
Authors: M Velásquez, LF Peláez, M Rojas, R Narváez-Sá, JA Velásquez, C Escudero, S San Martín, ÁP Cadavid
Frontiers in Physiology, 2021-12-02;12(0):764702.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
The FGF, TGF&beta and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells
Authors: MS Rahman, W Wruck, LS Spitzhorn, L Nguyen, M Bohndorf, S Martins, F Asar, A Ncube, L Erichsen, N Graffmann, J Adjaye
Sci Rep, 2020-01-20;10(1):739.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Interplay of Plasmodium falciparum and thrombin in brain endothelial barrier disruption
Authors: M Avril, M Benjamin, MM Dols, JD Smith
Sci Rep, 2019-09-11;9(1):13142.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Effects of gravitational mechanical unloading in endothelial cells: association between caveolins, inflammation and adhesion molecules.
Authors: Grenon S, Jeanne M, Aguado-Zuniga J, Conte M, Hughes-Fulford M
Sci Rep, 2013-01-01;3(0):1494.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injury.
Authors: Angelotti ML, Ronconi E, Ballerini L, Peired A, Mazzinghi B, Sagrinati C, Parente E, Gacci M, Carini M, Rotondi M, Fogo AB, Lazzeri E, Lasagni L, Romagnani P
Stem Cells, 2012-08-01;30(8):1714-25.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC
Expression, Regulation, and Function of Atypical Chemerin Receptor CCRL2 on Endothelial Cells.
Authors: Monnier J, Lewen S, O'Hara E, Huang K, Tu H, Butcher EC, Zabel BA
J. Immunol., 2012-06-13;189(2):956-67.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
Protein C activation peptide inhibits the expression of ICAM-1, VCAM-1, and interleukin-8 induced by TNF-a in human dermal microvascular endothelial cells
Authors: María Del Socorro Pina-Canseco, Araceli Páez-Arenas, Felipe Massó, Eduardo Pérez-Campos, Ruth Martínez-Cruz, Pedro Hernández-Cruz et al.
Folia Histochemica et Cytobiologica