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Human VEGF DuoSet ELISA

Catalog #: DY293B
195 Citations 13 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
DY293B
DY293B-05
Ancillary Products Available
DY008B: DuoSet ELISA Ancillary Reagent Kit 2
DY999B: Substrate Reagent Pack
DY999: Substrate Reagent Pack
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Human VEGF ELISA Standard Curve
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Product Details
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Citations (195)
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Summary Product Features Kit Content Other Reagents Required Data Examples Product Datasheets Preparation and Storage Background

Human VEGF DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
31.2 - 2,000 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human VEGF. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

 

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Scientific Data

N/A Human VEGF ELISA Standard Curve View Larger

Human VEGF ELISA Standard Curve

N/A Human VEGF DuoSet ELISA View Larger

Human VEGF DuoSet ELISA Effects of cell stress on VEGF-A and HIF1 alpha expression in Müller cells and Y79 photoreceptors. (A) VEGF-A was measured by ELISA using conditioned media collected from MIO-M1 and Y79 cells, n = 4–5/group in Müller cells and n = 8/group in Y79 photoreceptors, ** p < 0.01; (B) Western blots for HIF1 alpha using cellular proteins, n = 4/group, ** p < 0.01. For MIO-M1 Müller cells: Grey bars: 5 mM glucose. Black bars: 25 mM glucose. For Y79 photoreceptors: Grey bars: 11 mM glucose. Black bars: 25 mM glucose. NS, not significant; LG, low glucose; HG, high glucose. Image collected and cropped by CiteAb from the following open publication (https://www.mdpi.com/1422-0067/18/3/533), licensed under a CC-BY license. Not internally tested by R&D Systems.

Product Datasheets

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Product Datasheet
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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: VEGF

Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult (1-3). It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues in a cystine knot structure and the formation of antiparallel disulfide-linked dimers (4). Humans express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length (4). VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189 (3, 4). Isoforms other than VEGF121 contain basic heparin-binding regions and are not freely diffusible (4). Human VEGF165 shares 88% aa sequence identity with corresponding regions of mouse and rat VEGF. VEGF is expressed in multiple cells and tissues including skeletal and cardiac muscle (5, 6), hepatocytes (7), osteoblasts (8), neutrophils (9), macrophages (10), keratinocytes (11), brown adipose tissue (12), CD34+ stem cells (13), endothelial cells (14), fibroblasts, and vascular smooth muscle cells (15). VEGF expression is induced by hypoxia and cytokines such as IL-1, IL-6, IL-8, oncostatin M, and TNF-alpha (3, 4, 9, 16). VEGF isoforms are differentially expressed during development and in the adult (3). 

VEGF dimers bind to two related receptor tyrosine kinases, VEGF R1 (also called Flt-1) and VEGF R2 (Flk-1/KDR), and induce their homodimerization and autophosphorylation (3, 4, 7, 17, 18). These receptors have seven extracellular immunoglobulin-like domains and an intracellular split tyrosine kinase domain. They are expressed on vascular endothelial cells and a range of non-endothelial cells. Although VEGF affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity (3, 4). VEGF165 also binds the semaphorin receptor, neuropilin-1, which promotes complex formation with VEGF R2 (19). 
VEGF is best known for its role in vasculogenesis. During embryogenesis, VEGF regulates the proliferation, migration, and survival of endothelial cells (3, 4), thus regulating blood vessel density and size, but playing no role in determining vascular patterns. VEGF promotes bone formation through osteoblast and chondroblast recruitment and is also a monocyte chemoattractant (20-22). After birth, VEGF maintains endothelial cell integrity and is a potent mitogen for micro- and macro-vascular endothelial cells. In adults, VEGF functions mainly in wound healing and the female reproductive cycle (3). In diseased tissues, VEGF promotes vascular permeability. It is thus thought to contribute to tumor metastasis by promoting both extravasation and tumor angiogenesis (23, 24). Various strategies have been employed therapeutically to antagonize VEGF-mediated tumor angiogenesis (25). Circulating VEGF levels correlate with disease activity in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (26).

Long Name:
Vascular Endothelial Growth Factor
Entrez Gene IDs:
7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
Alternate Names:
MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

 

Citations for Human VEGF DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

195 Citations: Showing 1 - 10
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  1. Clustered ARPE-19 cells distinct in mitochondrial membrane potential may play a pivotal role in cell differentiation
    Authors: Miyatani, T;Tanaka, H;Numa, K;Uehara, A;Otsuki, Y;Hamuro, J;Kinoshita, S;Sotozono, C;
    Scientific reports
    Species: Human
    Sample Types: Cell Culture Supernates
  2. Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson's disease models
    Authors: Delila, L;Nebie, O;Le, NTN;Timmerman, K;Lee, DY;Wu, YW;Chou, ML;Buée, L;Chou, SY;Blum, D;Devos, D;Burnouf, T;
    Journal of biomedical science
    Species: Human
    Sample Types: Extracellular Vesicles
  3. Loss of Tuberous Sclerosis Complex 2 confers inflammation via dysregulation of Nuclear factor kappa-light-chain-enhancer of activated B cells
    Authors: McPhail, DK;Alzahrani, MAM;Martin, KR;Calver, BL;Harwood, AJ;MacKeigan, JP;Davies, DM;Tee, AR;
    Research square
    Species: Human
    Sample Types: Cell Culture Supernates
  4. Glycogen myophosphorylase loss causes increased dependence on glucose in iPSC-derived retinal pigment epithelium
    Authors: Basu, B;Karwatka, M;China, B;McKibbin, M;Khan, K;Inglehearn, CF;Ladbury, JE;Johnson, CA;
    The Journal of biological chemistry
    Species: Human
    Sample Types: Cell Culture Supernates
  5. Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S
    Authors: Zisman, D;Sabtan, H;Rahat, MM;Simanovich, E;Haddad, A;Gazitt, T;Feld, J;Slobodin, G;Kibari, A;Elias, M;Rahat, MA;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  6. The Reduction of PSMB4 in T24 and J82 Bladder Cancer Cells Inhibits the Angiogenesis and Migration of Endothelial Cells
    Authors: Lin, YH;Chen, TM;Tsai, YL;Tsai, WC;Wang, HH;Chen, Y;Wu, ST;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates
  7. Bone Regenerative Effect of Injectable Hypoxia Preconditioned Serum-Fibrin (HPS-F) in an Ex Vivo Bone Defect Model
    Authors: Jiang, J;Röper, L;Fuchs, F;Hanschen, M;Failer, S;Alageel, S;Cong, X;Dornseifer, U;Schilling, AF;Machens, HG;Moog, P;
    International journal of molecular sciences
    Species: Human
    Sample Types: Serum
  8. Investigating the paracrine and juxtacrine abilities of adipose-derived stromal cells in angiogenesis triple cell co-cultures
    Authors: Harary Søndergaard, R;Drozd Højgaard, L;Haack-Sørensen, M;Hoeeg, C;Mønsted Johansen, E;Follin, B;Kastrup, J;Ekblond, A;Juhl, M;
    Stem cell research
    Species: Human
    Sample Types: Cell Culture Supernates
  9. Assessment of the Integrity and Function of Human Term Placental Explants in Short-Term Culture
    Authors: López-Guzmán, C;García, AM;Marín, P;Vásquez, AM;
    Methods and protocols
    Species: Human
    Sample Types: Cell Culture Supernates
  10. High FSH levels impair VEGF secretion of human, frozen-thawed ovarian cortical tissue in vitro
    Authors: Einenkel, R;Schallmoser, A;Sänger, N;
    Scientific reports
    Species: Human
    Sample Types: Cell Culture Supernates
  11. Exploring the potential use of platelet rich plasma (PRP) from adult and umbilical cord blood in murine follicle culture
    Authors: Subiran Adrados, C;Cadenas, J;Polat, SL;Tjäder, AS;Blanche, P;Kristensen, SG;
    Reproductive biology
    Species: Human
    Sample Types: Platelet Lysates
  12. Ventilatory support and inflammatory peptides in hospitalised patients with COVID-19: A prospective cohort trial
    Authors: Gysan, MR;Milacek, C;Bal, C;Zech, A;Brugger, J;Milos, RI;Antoniewicz, L;Idzko, M;Gompelmann, D;
    PloS one
    Species: Human
    Sample Types: Serum
  13. Surgical Site-Released Tissue Is Potent to Generate Bone onto TCP and PCL-TCP Scaffolds In Vitro
    Authors: Rehage, E;Sowislok, A;Busch, A;Papaeleftheriou, E;Jansen, M;Jäger, M;
    International journal of molecular sciences
    Species: Human
    Sample Types: Serum
  14. Unrevealed roles of extracellular enolase?1 (ENO1) in promoting glycolysis and pro?cancer activities in multiple myeloma via hypoxia?inducible factor 1?
    Authors: Chung, IC;Huang, WC;Huang, YT;Chen, ML;Tsai, AW;Wu, PY;Yuan, TT;
    Oncology reports
    Species: Human, Mouse
    Sample Types: Cell Culture Supernates
  15. CD40 Ligand-CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy
    Authors: Abu El-Asrar, AM;Nawaz, MI;Ahmad, A;Dillemans, L;Siddiquei, M;Allegaert, E;Gikandi, PW;De Hertogh, G;Opdenakker, G;Struyf, S;
    International journal of molecular sciences
    Species: Human
    Sample Types: Cell Culture Supernates, Vitreous Humor
  16. Adipose stromal cells bioproducts as cell-free therapies: manufacturing and therapeutic dose determine in vitro functionality
    Authors: Skovronova, R;Scaccia, E;Calcat-I-Cervera, S;Bussolati, B;O'Brien, T;Bieback, K;
    Journal of translational medicine
    Species: Human
    Sample Types: Cell Lysates
  17. Transplantation of adipose tissue-derived microvascular fragments promotes therapy of critical limb ischemia
    Authors: Park, GT;Lim, JK;Choi, EB;Lim, MJ;Yun, BY;Kim, DK;Yoon, JW;Hong, YG;Chang, JH;Bae, SH;Ahn, JY;Kim, JH;
    Biomaterials research
    Species: Human
    Sample Types: Cell Culture Supernates
  18. Harnessing EGLN1 Gene Editing to Amplify HIF-1 alpha and Enhance Human Angiogenic Response
    Authors: Shams, S;Stilhano, RS;Silva, EA;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Cell Culture Supernates
  19. Contribution of Mesenchymal Stem Cells from Obese Adipose Tissue to PD-L1 Over-Expression and Breast Cancer Progression through Pathogenic Th17 Cell Activation
    Authors: Blangero, F;Robert, M;Andraud, T;Dumontet, C;Vidal, H;Eljaafari, A;
    Cancers
    Species: Human
    Sample Types: Cell Culture Supernates
  20. Differential Impact of Intermittent vs. Sustained Hypoxia on HIF-1, VEGF and Proliferation of HepG2 Cells
    Authors: M Minoves, F Hazane-Puc, G Moriondo, A Boutin-Par, E Lemarié, JL Pépin, D Godin-Ribu, A Briançon-M
    International Journal of Molecular Sciences, 2023-04-07;24(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: ELISA
  21. Nailfold Videocapillaroscopy for Non-Invasive Assessment of Microcirculation and Prognostic Correlation with Endothelial Dysfunction, Cardiovascular Risk Factors, and Non-HLA Antibodies in Heart Transplant Recipients: A Pilot Study
    Authors: D Sikorska, D Kami?ska, R Catar, D Wu, H Zhao, P Wang, J Kamhieh-Mi, M Banasik, M Kusztal, M Cielecka, M Zakliczy?s, R Rutkowski, K Korybalska, H Heidecke, G Moll, W Samborski
    Journal of Clinical Medicine, 2023-03-16;12(6):.
    Species: Human
    Sample Types: Serum
  22. The Antimicrobial Peptide Cathelicidin Exerts Immunomodulatory Effects via Scavenger Receptors
    Authors: R Amagai, T Takahashi, H Terui, T Fujimura, K Yamasaki, S Aiba, Y Asano
    International Journal of Molecular Sciences, 2023-01-03;24(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  23. Effects of Exercise Training on Neurotrophic Factors and Blood-Brain Barrier Permeability in Young-Old and Old-Old Women
    Authors: SY Cho, HT Roh
    International Journal of Environmental Research and Public Health, 2022-12-16;19(24):.
    Species: Human
    Sample Types: Serum
  24. Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment
    Authors: L Sommerfeld, I Knuth, F Finkernage, J Pesek, WA Nockher, JM Jansen, U Wagner, A Nist, T Stiewe, S Müller-Brü, R Müller, S Reinartz
    Cancers, 2022-12-13;14(24):.
    Species: Human
    Sample Types:
  25. Macrophage NFATC2 mediates angiogenic signaling during mycobacterial infection
    Authors: WJ Brewer, AM Xet-Mull, A Yu, MI Sweeney, EM Walton, DM Tobin
    Cell Reports, 2022-12-13;41(11):111817.
    Species: Human
    Sample Types: Cell Culture Supernates
  26. Paracrine and Autocrine Effects of VEGF Are Enhanced in Human eMSC Spheroids
    Authors: I Kozhukharo, N Minkevich, L Alekseenko, A Domnina, O Lyublinska
    International Journal of Molecular Sciences, 2022-11-18;23(22):.
    Species: Human
    Sample Types: Cell Culture Supernates
  27. KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer
    Authors: J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi
    Cancer Research, 2022-11-15;0(0):OF1-OF14.
    Species: Human
    Sample Types: Cell Culture Supernates
  28. Angiogenic Potential of Human Adipose-Derived Mesenchymal Stromal Cells in Nanofibrillated Cellulose Hydrogel
    Authors: E Koivunotko, J Snirvi, A Merivaara, R Harjumäki, S Rautiainen, M Kelloniemi, K Kuismanen, S Miettinen, M Yliperttul, R Koivuniemi
    Biomedicines, 2022-10-15;10(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  29. Growth Factor Release within Liquid and Solid PRF
    Authors: K Zwittnig, B Kirnbauer, N Jakse, P Schlenke, I Mischak, S Ghanaati, S Al-Maawi, D Végh, M Payer, TA Zrnc
    Journal of Clinical Medicine, 2022-08-29;11(17):.
    Species: Human
    Sample Types: Serum
  30. Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis
    Authors: S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek
    Journal of ovarian research, 2022-07-26;15(1):87.
    Species: Human
    Sample Types: Cell Culture Supernates
  31. Kallistatin prevents ovarian hyperstimulation syndrome by regulating vascular leakage
    Authors: J Huang, Y Mao, Q Li, H Hong, N Tang, X Kang, Y Huang, J Liu, Q Gong, Y Yao, L Li
    Journal of Cellular and Molecular Medicine, 2022-07-21;26(16):4613-4623.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes
    Authors: SL Lu, H Omori, Y Zhou, YS Lin, CC Liu, JJ Wu, T Noda
    MBio, 2022-07-05;0(0):e0123322.
    Species: Human
    Sample Types: Serum
  33. VEGF-C serum level is associated with response to bevacizumab maintenance therapy in primary ovarian cancer patients
    Authors: Y Ding, L Oliveira-F, E Vettorazzi, K Legler, K Milde-Lang, L Woelber, A Jaeger, K Prieske, V Mueller, B Schmalfeld, S Kuerti
    PLoS ONE, 2022-06-10;17(6):e0269680.
    Species: Human
    Sample Types: Serum
  34. Sirtuin 1 Induces Choroidal Neovascularization and Triggers Age-Related Macular Degeneration by Promoting LCN2 through SOX9 Deacetylation
    Authors: S Zhao, Z Huang, H Jiang, J Xiu, L Zhang, Q Long, Y Yang, L Yu, L Lu, H Gu
    Oncogene, 2022-06-09;2022(0):1671438.
    Species: Human
    Sample Types: Cell Culture Supernates
  35. Nerve Growth Factor (NGF) as Partaker in the Modulation of UV-Response in Cultured Human Conjunctival Fibroblasts
    Authors: G Esposito, BO Balzamino, ML Rocco, L Aloe, A Micera
    International Journal of Molecular Sciences, 2022-06-06;23(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  36. Mg-based materials diminish tumor spreading and cancer metastases
    Authors: P Globig, R Madurawala, R Willumeit-, F Martini, E Mazzoni, BJC Luthringer
    Bioactive materials, 2022-05-10;19(0):594-610.
    Species: Human
    Sample Types: Cell Culture Supernates
  37. Therapeutic Effects of Platelet-Derived Extracellular Vesicles in a Bioengineered Tendon Disease Model
    Authors: AL Graça, RMA Domingues, I Calejo, M Gómez-Flor, ME Gomes
    International Journal of Molecular Sciences, 2022-03-09;23(6):.
    Species: Human
    Sample Types: Extracellular Vesicles
  38. Anti-inflammatory effects of an autologous gold-based serum therapy in osteoarthritis patients
    Authors: J Feldt, AJ Donaubauer, J Welss, U Schneider, US Gaipl, F Paulsen
    Scientific Reports, 2022-03-03;12(1):3560.
    Species: Human
    Sample Types: Serum
  39. Depolymerization of fucoidan with endo-fucoidanase changes bioactivity in processes relevant for bone regeneration
    Authors: J Ohmes, MD Mikkelsen, TT Nguyen, VHN Tran, S Meier, MS Nielsen, M Ding, A Seekamp, AS Meyer, S Fuchs
    Carbohydrate polymers, 2022-02-24;286(0):119286.
    Species: Human
    Sample Types: Cell Culture Supernates
  40. Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors
    Authors: NB Nataraj, A Noronha, JS Lee, S Ghosh, HR Mohan Raju, A Sekar, B Zuckerman, M Lindzen, E Tarcitano, S Srivastava, M Selitrenni, I Livneh, D Drago-Garc, O Rueda, C Caldas, S Lev, T Geiger, A Ciechanove, I Ulitsky, R Seger, E Ruppin, Y Yarden
    Cell Reports, 2022-02-22;38(8):110418.
    Species: Human
    Sample Types: Cell Culture Supernates
  41. Non-HLA Antibodies in Hand Transplant Recipients Are Connected to Multiple Acute Rejection Episodes and Endothelial Activation
    Authors: D Sikorska, D Kami?ska, R Catar, M Banasik, H Heidecke, K Schulze-Fo, K Korybalska, R Rutkowski, J ?uczak, J Jab?ecki, A Oko, P Daroszewsk, M Kusztal, W Samborski
    Journal of Clinical Medicine, 2022-02-04;11(3):.
    Species: Human
    Sample Types: Serum
  42. MiR-612, miR-637, and miR-874 can Regulate VEGFA Expression in Hepatocellular Carcinoma Cell Lines
    Authors: MMU Castanhole, NM Tunissioll, ARCP Oliveira, MF Mattos, ALS Galbiatti-, RS Kawasaki-O, EC Pavarino, RF da Silva, EM Goloni-Ber
    Genes, 2022-01-30;13(2):.
    Species: Human
    Sample Types: Cell Lysates
  43. Circulating Interleukin-6 and CD16 positive monocytes increase following angioplasty of an arteriovenous fistula
    Authors: S Hakki, EJ Robinson, MG Robson
    Scientific Reports, 2022-01-26;12(1):1427.
    Species: Human
    Sample Types: Plasma
  44. Kidney injury biomarkers and parasitic loads of Schistosoma mansoni in a highly endemic area in northeastern Brazil
    Authors: RLF Galvão, GC Meneses, MCC Pinheiro, AMC Martins, EF Daher, FSM Bezerra
    Acta tropica, 2022-01-14;0(0):106311.
    Species: Human
    Sample Types: Urine
  45. Delivery of affordable and scalable encapsulated allogenic/autologous mesenchymal stem cells in coagulated platelet poor plasma for dental pulp regeneration
    Authors: I Angelopoul, C Trigo, MI Ortuzar, J Cuenca, C Brizuela, M Khoury
    Scientific Reports, 2022-01-10;12(1):435.
    Species: Human
    Sample Types: Cell Culture Supernates
  46. Tissue Inhibitor of Metalloproteinase-3 Ameliorates Diabetes-Induced Retinal Inflammation
    Authors: AM Abu El-Asr, A Ahmad, MI Nawaz, MM Siddiquei, A De Zutter, L Vanbrabant, PW Gikandi, G Opdenakker, S Struyf
    Frontiers in Physiology, 2022-01-10;12(0):807747.
    Species: Human
    Sample Types: Serum
  47. Mesenchymal stem cell-encapsulated cellulose nanofiber microbeads and enhanced biological activities by hyaluronic acid incorporation
    Authors: M Goh, G Tae
    Carbohydrate polymers, 2021-12-24;280(0):119026.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Microfluidic Single-Cell Proteomics Assay Chip: Lung Cancer Cell Line Case Study
    Authors: Y Jung, M Son, YR Nam, J Choi, JR Heath, S Yang
    Micromachines, 2021-09-23;12(10):.
    Species: Human
    Sample Types: Cell Lysates
  49. Pulmonary function changes in older adults with and without metabolic syndrome
    Authors: MAR Brandao-Ra, R Moraes-Fer, MC Oliveira-J, A Santos-Dia, ALL Bachi, G Gabriela-P, S de Oliveir, AC Araújo-Ros, LVF Oliveira, CR Frison, WL do Prado, RP Raju, PB Balagopal, RP Vieira
    Scientific Reports, 2021-08-30;11(1):17337.
    Species: Human
    Sample Types: Exhaled Breath Condensate (EBC)
  50. Evaluation of beta-Catenin Inhibition of Axitinib and Nitazoxanide in Human Monocyte-Derived Dendritic Cells
    Authors: W Azeem, RM Bakke, B Gabriel, S Appel, AM Øyan, KH Kalland
    Biomedicines, 2021-08-03;9(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  51. An In Vitro System to Study the Effect of Subchondral Bone Health on Articular Cartilage Repair in Humans
    Authors: T Hopkins, KT Wright, NJ Kuiper, S Roberts, P Jermin, P Gallacher, JH Kuiper
    Cells, 2021-07-27;10(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  52. PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
    Authors: S Ghosh, NB Nataraj, A Noronha, S Patkar, A Sekar, S Mukherjee, S Winograd-K, L Kramarski, A Verma, M Lindzen, DD Garcia, J Green, G Eisenberg, H Gil-Henn, A Basu, Y Lender, S Weiss, M Oren, M Lotem, B Geiger, E Ruppin, Y Yarden
    Cell Reports, 2021-05-25;35(8):109181.
    Species: Human
    Sample Types: Cell Culture Supernates
  53. HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway
    Authors: L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang
    Autophagy, 2021-05-24;0(0):1-20.
    Species: Rat
    Sample Types: Serum
  54. VEGF counteracts amyloid-&beta-induced synaptic dysfunction
    Authors: L Martin, P Bouvet, N Chounlamou, C Watrin, R Besançon, D Pinatel, D Meyronet, J Honnorat, A Buisson, PA Salin, C Meissirel
    Cell Reports, 2021-05-11;35(6):109121.
    Species: Human
    Sample Types: Cell Culture Supernates
  55. Plasma markers in pulmonary hypertension subgroups correlate with patient survival
    Authors: T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars
    Respiratory Research, 2021-05-04;22(1):137.
    Species: Human
    Sample Types: Plasma
  56. Targeting autocrine amphiregulin robustly and reproducibly inhibits ovarian cancer in a syngeneic model: roles for wildtype p53
    Authors: M Lindzen, S Ghosh, A Noronha, D Drago, NB Nataraj, O Leitner, S Carvalho, E Zmora, S Sapoznik, KB Shany, K Levanon, D Aderka, BS Ramírez, M Dahlhoff, I McNeish, Y Yarden
    Oncogene, 2021-04-30;0(0):.
    Species: Human
    Sample Types: Ascites Fluid
  57. Transcriptional Regulation of Thrombin-Induced Endothelial VEGF Induction and Proangiogenic Response
    Authors: R Catar, G Moll, I Hosp, M Simon, C Luecht, H Zhao, D Wu, L Chen, J Kamhieh-Mi, K Korybalska, D Zickler, J Witowski
    Cells, 2021-04-15;10(4):.
    Species: Human
    Sample Types: Cell Culture Supernates
  58. Sinularin, an Anti-Cancer Agent Causing Mitochondria-Modulated Apoptosis and Cytoskeleton Disruption in Human Hepatocellular Carcinoma
    Authors: CY Ko, PC Shih, PW Huang, YH Lee, YF Chen, MH Tai, CH Liu, ZH Wen, HM Kuo
    International Journal of Molecular Sciences, 2021-04-11;22(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. Melanoma Associated Chitinase 3-Like 1 Promoted Endothelial Cell Activation and Immune Cell Recruitment
    Authors: G Ramos-Espi, Y Wang, JM Brandner, SW Schneider, C Gorzelanny
    International Journal of Molecular Sciences, 2021-04-10;22(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  60. Effects of Bovine Colostrum with or without Egg on In Vitro Bacterial-Induced Intestinal Damage with Relevance for SIBO and Infectious Diarrhea
    Authors: RJ Playford, N Choudhry, P Kelly, T Marchbank
    Nutrients, 2021-03-22;13(3):.
    Species: Human
    Sample Types: Cell Lysates
  61. TGF&beta1 induces in-vitro and ex-vivo angiogenesis through VEGF production in human ovarian follicular fluid-derived granulosa cells during in-vitro fertilization cycle
    Authors: TH Lai, HT Chen, WB Wu
    Journal of reproductive immunology, 2021-03-20;145(0):103311.
    Species: Human
    Sample Types: Cell Culture Supernates
  62. The effects of resveratrol on the expression of VEGF, TGF-&beta, and MMP-9 in endometrial stromal cells of women with endometriosis
    Authors: T Arablou, N Aryaeian, S Khodaverdi, R Kolahdouz-, Z Moradi, N Rashidi, AA Delbandi
    Scientific Reports, 2021-03-15;11(1):6054.
    Species: Human
    Sample Types: Cell Culture Supernates
  63. The NFIB-ERO1A axis promotes breast cancer metastatic colonization of disseminated tumour cells
    Authors: F Zilli, P Marques Ra, P Auf der Ma, C Jehanno, A Sethi, MM Coissieux, T Eichlisber, L Sauteur, A Rouchon, L Bonapace, J Pinto Cout, R Rad, MR Jensen, A Banfi, MB Stadler, M Bentires-A
    Embo Molecular Medicine, 2021-03-10;0(0):e13162.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Initial Identification of UDP-Glucose Dehydrogenase as a Prognostic Marker in Breast Cancer Patients, Which Facilitates Epirubicin Resistance and Regulates Hyaluronan Synthesis in MDA-MB-231 Cells
    Authors: DL Vitale, I Caon, A Parnigoni, I Sevic, FM Spinelli, A Icardi, A Passi, D Vigetti, L Alaniz
    Biomolecules, 2021-02-09;11(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  65. The Influence of Melatonin and Light on VEGF Secretion in Primary RPE Cells
    Authors: A Klettner, M Kampers, D Töbelmann, J Roider, M Dittmar
    Biomolecules, 2021-01-16;11(1):.
    Species: Porcine
    Sample Types: Cell Culture Supernates
  66. IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors
    Authors: L Cristinzia, R Poto, G Criscuolo, AL Ferrara, MR Galdiero, L Modestino, S Loffredo, A de Paulis, G Marone, G Spadaro, G Varricchi
    Cells, 2021-01-12;10(1):.
    Species: Human
    Sample Types: Cell Culture Supernates
  67. Evaluation of a Brown Seaweed Extract from Dictyosiphon foeniculaceus as a Potential Therapeutic Agent for the Treatment of Glioblastoma and Uveal Melanoma
    Authors: P Dörschmann, C Schmitt, KS Bittkau, S Neupane, M Synowitz, J Roider, S Alban, J Held-Feind, A Klettner
    Marine Drugs, 2020-12-08;18(12):.
    Species: Human
    Sample Types: Cell Culture Supernates
  68. Proteomics of regenerated tissue in response to a titanium implant with a bioactive surface in a rat tibial defect model
    Authors: RM Boteanu, VI Suica, L Ivan, F Safciuc, E Uyy, E Dragan, SM Croitoru, V Grumezescu, M Chiritoiu, LE Sima, C Vlagioiu, G Socol, F Antohe
    Sci Rep, 2020-10-28;10(1):18493.
    Species: Rat
    Sample Types: Cell Culture Supernates
  69. Abnormal Nailfold Capillaries in Patients after Hand Transplantation
    Authors: D Sikorska, W Samborski, D Kami?ska, M Kusztal, J Jab?ecki, K Nijakowski, A Oko, M Karczewski, K Korybalska, J Witowski
    J Clin Med, 2020-10-25;9(11):.
    Species: Human
    Sample Types: Serum
  70. Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy
    Authors: M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg
    Mol Ther, 2020-10-15;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  71. The role of EMMPRIN/CD147 in regulating angiogenesis in patients with psoriatic arthritis
    Authors: MA Rahat, M Safieh, E Simanovich, E Pasand, T Gazitt, A Haddad, M Elias, D Zisman
    Arthritis Res Ther, 2020-10-14;22(1):240.
    Species: Human
    Sample Types: Serum
  72. Effect of Enzymatically Extracted Fucoidans on Angiogenesis and Osteogenesis in Primary Cell Culture Systems Mimicking Bone Tissue Environment
    Authors: J Ohmes, Y Xiao, F Wang, MD Mikkelsen, TT Nguyen, H Schmidt, A Seekamp, AS Meyer, S Fuchs
    Mar Drugs, 2020-09-21;18(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  73. Ischemia-Like Stress Conditions Stimulate Trophic Activities of Adipose-Derived Stromal/Stem Cells
    Authors: J Bachmann, E Ehlert, M Becker, C Otto, K Radeloff, T Blunk, P Bauer-Krei
    Cells, 2020-08-21;9(9):.
    Species: Human
    Sample Types: Cell Culture Supernates
  74. VEGFA and NFE2L2 Gene Expression and Regulation by MicroRNAs in Thyroid Papillary Cancer and Colloid Goiter
    Authors: LP Stuchi, MMU Castanhole, N Maniezzo-S, PM Biselli-Ch, T Henrique, JA Padovani N, D de-Santi N, AP Girol, EC Pavarino, EM Goloni-Ber
    Genes (Basel), 2020-08-19;11(9):.
    Species: Human
    Sample Types: Tissue Homogenates
  75. Differential expression of angiogenesis-related miRNAs and VEGFA in cirrhosis and hepatocellular carcinoma
    Authors: ARCP de Oliveir, MMU Castanhole, PM Biselli-Ch, ÉC Pavarino, RCMA da Silva, RF da Silva, EM Goloni-Ber
    Arch Med Sci, 2020-08-10;16(5):1150-1157.
    Species: Human
    Sample Types: Protein
  76. Bis(maltolato)oxovanadium(IV) Induces Angiogenesis via Phosphorylation of VEGFR2
    Authors: L Parma, HAB Peters, ME Johansson, S Gutiérrez, H Meijerink, S de Kimpe, MR de Vries, PHA Quax
    Int J Mol Sci, 2020-06-30;21(13):.
    Species: Human
    Sample Types: Cell Culture Supernates
  77. Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells
    Authors: A Allen, N Vaninov, M Li, S Nguyen, P Igo, AW Tilles, B O'Rourke, BLK Miller, B Parekkadan, RN Barcia
    Sci Rep, 2020-06-23;10(1):10142.
    Species: Human
    Sample Types: Cell Culture Supernates
  78. Angiopoietins, Vascular Endothelial Growth Factors and Secretory Phospholipase A2 in Ischemic and Non-Ischemic Heart Failure
    Authors: G Varricchi, S Loffredo, L Bencivenga, AL Ferrara, G Gambino, N Ferrara, A de Paulis, G Marone, G Rengo
    J Clin Med, 2020-06-19;9(6):.
    Species: Human
    Sample Types: Plasma
  79. miR-23a-3p is a Key Regulator of IL-17C-Induced Tumor Angiogenesis in Colorectal Cancer
    Authors: Y Lee, SJ Kim, J Choo, G Heo, JW Yoo, Y Jung, SH Rhee, E Im
    Cells, 2020-06-01;9(6):.
    Species: Human, Xenograft
    Sample Types: Cell Culture Supernates
  80. Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy
    Authors: SJ Wang, R Li, TSC Ng, G Luthria, MJ Oudin, M Prytyskach, RH Kohler, R Weissleder, DA Lauffenbur, MA Miller
    Sci Adv, 2020-05-22;6(21):eaaz8521.
    Species: Human
    Sample Types: Cell Lysates
  81. Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses
    Authors: L Mercurio, CM Failla, L Capriotti, C Scarponi, F Facchiano, M Morelli, S Rossi, G Pagnanelli, C Albanesi, A Cavani, S Madonna
    PLoS ONE, 2020-04-30;15(4):e0222969.
    Species: Human
    Sample Types: Cell Culture Supernates
  82. A Cross-Sectional Study Evaluating the Effects of Resistance Exercise on Inflammation and Neurotrophic Factors in Elderly Women with Obesity
    Authors: HT Roh, SY Cho, WY So
    J Clin Med, 2020-03-20;9(3):.
    Species: Human
    Sample Types: Serum
  83. Apelin Affects the Progression of Osteoarthritis by Regulating VEGF-Dependent Angiogenesis and miR-150-5p Expression in Human Synovial Fibroblasts
    Authors: YH Wang, SJ Kuo, SC Liu, SW Wang, CH Tsai, YC Fong, CH Tang
    Cells, 2020-03-02;9(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  84. VEGF-A165b levels are reduced in breast cancer patients at primary diagnosis but increase after completion of cancer treatment
    Authors: MM Karsten, MH Beck, A Rademacher, J Knabl, JU Blohmer, J Jückstock, JC Radosa, P Jank, B Rack, W Janni
    Sci Rep, 2020-02-27;10(1):3635.
    Species: Human
    Sample Types: Whole Blood
  85. Vitamin-D3 (&alpha-1, 25(OH) 2D3) Protects Retinal Pigment Epithelium From Hyperoxic Insults
    Authors: P Murugeswar, A Firoz, S Murali, A Vinekar, L Krishna, VR Anandula, N Jeyabalan, P Chevour, C Jayadev, R Shetty, G Carpentier, G Kumaramani, A Ghosh, D Das
    Invest. Ophthalmol. Vis. Sci., 2020-02-07;61(2):4.
    Species: Human
    Sample Types: Cell Culture Superantes
  86. Are the Immune Properties of Mesenchymal Stem Cells from Wharton's Jelly Maintained during Chondrogenic Differentiation?
    Authors: C Voisin, G Cauchois, L Reppel, C Laroye, L Louarn, C Schenowitz, P Sonon, I Poras, V Wang, E D Carosell, N Benkirane-, P Moreau, N Rouas-Frei, D Bensoussan, C Huselstein
    J Clin Med, 2020-02-04;9(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  87. A Cell-Free SDKP-Conjugated Self-Assembling Peptide Hydrogel Sufficient for Improvement of Myocardial Infarction
    Authors: S Firoozi, S Pahlavan, MH Ghanian, S Rabbani, S Tavakol, M Barekat, S Yakhkeshi, E Mahmoudi, M Soleymani, H Baharvand
    Biomolecules, 2020-01-30;10(2):.
    Species: Human
    Sample Types: Cell Culture Supernates
  88. Vascular Endothelial Growth Factor A and VEGFR-1 Change during Preimplantation in Heifers
    Authors: D Chiumia, AK Hankele, AE Groebner, K Schulke, HD Reichenbac, K Giller, V Zakhartche, S Bauersachs, SE Ulbrich
    Int J Mol Sci, 2020-01-15;21(2):.
    Species: Bovine
    Sample Types: Tissue Homogenates
  89. Short Communication: Interaction of Nerve Growth Factor (NGF) and Vascular Endothelial Growth Factor (VEGF) in Healthy Individuals
    Authors: A Groh, K Jahn, M Gröschl, T Hillemache, J Kornhuber, S Bleich, H Frieling, A Heberlein
    Dis. Markers, 2019-11-11;2019(0):7510315.
    Species: Human
    Sample Types: Serum
  90. Mechanism and Consequences of The Impaired Hif-1alpha Response to Hypoxia in Human Proximal Tubular HK-2 Cells Exposed to High Glucose
    Authors: C García-Pas, S Benito-Mar, V Moreno-Man, AB Fernández-, FJ Lucio-Caza
    Sci Rep, 2019-11-01;9(1):15868.
    Species: Human
    Sample Types: Whole Cells
  91. The neuroprotective activity of heat-treated human platelet lysate biomaterials manufactured from outdated pathogen-reduced (amotosalen/UVA) platelet concentrates
    Authors: O Nebie, D Devos, V Vingtdeux, L Barro, JC Devedjian, A Jonneaux, ML Chou, R Bordet, L Buée, F Knutson, D Blum, T Burnouf
    J. Biomed. Sci., 2019-10-31;26(1):89.
    Species: Human
    Sample Types: Cell Culture Supernates
  92. Greater Circulating Copper Concentrations and Copper/Zinc Ratios are Associated with Lower Psychological Distress, But Not Cognitive Performance, in a Sample of Australian Older Adults
    Authors: M Mravunac, EA Szymlek-Ga, R M Daly, B R Roberts, M Formica, J Gianoudis, S L O'Connel, C A Nowson, B R Cardoso
    Nutrients, 2019-10-17;11(10):.
    Species: Human
    Sample Types: Serum
  93. Effects of Sulfated Fucans from Laminaria hyperborea Regarding VEGF Secretion, Cell Viability, and Oxidative Stress and Correlation with Molecular Weight
    Authors: P Dörschmann, G Kopplin, J Roider, A Klettner
    Mar Drugs, 2019-09-25;17(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  94. Visual hallucinations in Alzheimer's disease do not seem to be associated with chronic hypoperfusion of to visual processing areas V2 and V3 but may be associated with reduced cholinergic input to these areas
    Authors: LI Sinclair, A Kumar, T Darreh-Sho, S Love
    Alzheimers Res Ther, 2019-09-12;11(1):80.
    Species: Human
    Sample Types: Tissue Homogenates
  95. A Model Based on the Combination of IFN-gamma, IP-10, Ferritin and 25-Hydroxyvitamin D for Discriminating Latent From Active Tuberculosis in Children
    Authors: P Comella-De, R Abellana, R Villar-Her, MD Jean Coute, B Sallés Min, L Canales Al, M Narcisse, J Gautier, C Ascaso, I Latorre, J Dominguez, TM Perez-Porc
    Front Microbiol, 2019-08-14;10(0):1855.
    Species: Human
    Sample Types: Plasma
  96. Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
    Authors: JH Low, P Li, EGY Chew, B Zhou, K Suzuki, T Zhang, MM Lian, M Liu, E Aizawa, C Rodriguez, KSM Yong, Q Chen, JM Campistol, M Fang, CC Khor, JN Foo, JC Izpisua Be, Y Xia
    Cell Stem Cell, 2019-07-11;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  97. Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment
    Authors: O Mucha, P Podkalicka, M Mikulski, S Barwacz, K Andrysiak, A Biela, M Mieczkowsk, N Kachamakov, D Ryszawy, A Bia?as, B Szel??ek, P Grudnik, E Majewska, K Michalik, K Jakubiec, M Bie?, N Witkowska, K Gluza, D Ekonomiuk, K Sitarz, M Ga??zowski, K Brzózka, G Dubin, A Józkowicz, J Dulak, A ?oboda
    Arch. Biochem. Biophys., 2019-07-02;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  98. miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A
    Authors: S Caporali, A Amaro, L Levati, E Alvino, PM Lacal, S Mastroeni, F Ruffini, L Bonmassar, GC Antonini C, N Felli, A Carè, U Pfeffer, S D'Atri
    J. Exp. Clin. Cancer Res., 2019-06-21;38(1):272.
    Species: Human
    Sample Types: Serum
  99. A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer
    Authors: M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek
    Cancers (Basel), 2019-05-13;11(5):.
    Species: Human
    Sample Types: Cell Culture Supernates
  100. Optimizing Measurement of Vascular Endothelial Growth Factor in Small Blood Samples of Premature Infants
    Authors: CC Lopez Yoma, KT Preissner, B Lorenz, K Stieger
    Sci Rep, 2019-05-01;9(1):6744.
    Species: Human
    Sample Types: Serum
  101. Superantigenic Activation of Human Cardiac Mast Cells
    Authors: G Varricchi, S Loffredo, F Borriello, A Pecoraro, F Rivellese, A Genovese, G Spadaro, G Marone
    Int J Mol Sci, 2019-04-12;20(8):.
    Species: Human
    Sample Types: Cell Culture Supernates
  102. Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels
    Authors: EJ Campbell, GU Dachs, HR Morrin, VC Davey, BA Robinson, MCM Vissers
    BMC Cancer, 2019-04-03;19(1):307.
    Species: Human
    Sample Types: Tissue Homogenates
  103. Plasma Rich in Growth Factors (PRGF) Disrupt the Blood-Brain Barrier Integrity and Elevate Amyloid Pathology in the Brains of 5XFAD Mice
    Authors: QV Duong, ML Kintzing, WE Kintzing, IM Abdallah, AD Brannen, A Kaddoumi
    Int J Mol Sci, 2019-03-25;20(6):.
    Species: Human
    Sample Types: Plasma
  104. Ultrasonic Generation of Pulsatile and Sequential Therapeutic Delivery Profiles from Calcium-Crosslinked Alginate Hydrogels
    Authors: T Emi, K Michaud, E Orton, G Santilli, C Linh, M O'Connell, F Issa, S Kennedy
    Molecules, 2019-03-16;24(6):.
    Species: Human
    Sample Types: Hydrogel Fluid
  105. Angiogenic Properties of Menstrual Stem Cells Are Impaired in Women with a History of Preeclampsia
    Authors: M Varas-Godo, S Acuña-Gall, S Venegas-Du, C Hill, A Caceres-Ve, O Realini, LJ Monteiro, G Zavala, M Khoury, R Romero, G Rice, SE Illanes
    Stem Cells Int, 2019-01-27;2019(0):1916542.
    Species: Human
    Sample Types: Cell Culture Supernates
  106. Hepatic blood flow by perfusion computed tomography as an imaging biomarker for patients with gastric cancer
    Authors: K Shuto, M Mori, C Kosugi, K Narushima, S Nakabayash, T Fujisiro, A Sato, K Hayano, H Shimizu, K Koda
    Oncol Lett, 2019-01-25;17(3):3267-3276.
    Species: Human
    Sample Types: Serum
  107. Four types of human platelet lysate, including one virally inactivated by solvent-detergent, can be used to propagate Wharton Jelly mesenchymal stromal cells
    Authors: MS Chen, TJ Wang, HC Lin, B Thierry
    New biotechnology, 2018-11-20;0(0):.
    Species: Human
    Sample Types: Platelet Lysates
  108. Co-Expression of VEGF and IL-6 Family Cytokines is Associated with Decreased Survival in HER2 Negative Breast Cancer Patients: Subtype-Specific IL-6 Family Cytokine-Mediated VEGF Secretion
    Authors: K Tawara, H Scott, J Emathinger, A Ide, R Fox, D Greiner, D LaJoie, D Hedeen, M Nandakumar, AJ Oler, R Holzer, C Jorcyk
    Transl Oncol, 2018-11-12;12(2):245-255.
    Species: Human
    Sample Types: Cell Culture Supernates
  109. Combining Calcium Phosphates with Polysaccharides: A Bone-Inspired Material Modulating Monocyte/Macrophage Early Inflammatory Response
    Authors: H Rammal, C Bour, M Dubus, L Entz, L Aubert, SC Gangloff, S Audonnet, NB Bercu, F Boulmedais, C Mauprivez, H Kerdjoudj
    Int J Mol Sci, 2018-11-03;19(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  110. Tissue-engineered 3D melanoma model with blood and lymphatic capillaries for drug development
    Authors: J Bourland, J Fradette, FA Auger
    Sci Rep, 2018-09-04;8(1):13191.
    Species: Human
    Sample Types: Cell Culture Supernates
  111. Serum from patients with chronic obstructive pulmonary disease induces senescence-related phenotype in bronchial epithelial cells
    Authors: B Ku?nar-Kam, J Miku?a-Pie, A Witucka, A Romaniuk, N Konieczna, B Rubi?, K Ksi??ek, A Tykarski, H Batura-Gab
    Sci Rep, 2018-08-28;8(1):12940.
    Species: Human
    Sample Types: Cell Culture Supernates
  112. Novel oncogenic and chemoresistance-inducing functions of resistin in ovarian cancer cells require miRNAs-mediated induction of epithelial-to-mesenchymal transition
    Authors: L Qiu, GF Zhang, L Yu, HY Wang, XJ Jia, TJ Wang
    Sci Rep, 2018-08-21;8(1):12522.
    Species: Human
    Sample Types: Cell Culture Supernates
  113. Transplantation of Allogeneic Pericytes Improves Myocardial Vascularization and Reduces Interstitial Fibrosis in a Swine Model of Reperfused Acute Myocardial Infarction
    Authors: VV Alvino, R Fernández-, I Rodriguez-, S Slater, G Mangialard, E Avolio, H Spencer, L Culliford, S Hassan, L Sueiro Bal, A Herman, A Ayaon-Alba, C Galán-Arri, J Sánchez-Go, H Hennessey, C Delmege, R Ascione, C Emanueli, GD Angelini, B Ibanez, P Madeddu
    J Am Heart Assoc, 2018-01-22;7(2):.
    Species: Porcine
    Sample Types: Cell Culture Supernates
  114. Comparative Analysis of Different Platelet Lysates and Platelet Rich Preparations to Stimulate Tendon Cell Biology: An In Vitro Study
    Authors: F Klatte-Sch, T Schmidt, M Uckert, S Scheffler, U Kalus, M Rojewski, H Schrezenme, A Pruss, B Wildemann
    Int J Mol Sci, 2018-01-10;19(1):.
    Species: Human
    Sample Types: Plasma
  115. ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT
    Authors: CY Lin, CF Cho, ST Bai, JP Liu, TT Kuo, LJ Wang, YS Lin, CC Lin, LC Lai, TP Lu, CY Hsieh, CN Chu, DC Cheng, YP Sher
    Sci Rep, 2017-11-08;7(1):15108.
    Species: Human
    Sample Types: Cell Culture Supernates
  116. The Effect of Aquaporin 1-Inhibition on Vasculogenic Mimicry in Malignant Mesothelioma
    Authors: E Pulford, J McEvoy, A Hocking, S Prabhakara, K Griggs, S Klebe
    Int J Mol Sci, 2017-11-01;18(11):.
    Species: Human
    Sample Types: Cell Culture Supernates
  117. Collagen-Based Medical Device as a Stem Cell Carrier for Regenerative Medicine
    Authors: L Aubert, M Dubus, H Rammal, C Bour, C Mongaret, C Boulagnon-, R Garnotel, C Schneider, R Rahouadj, C Laurent, SC Gangloff, F Velard, C Mauprivez, H Kerdjoudj
    Int J Mol Sci, 2017-10-21;18(10):.
    Species: Human
    Sample Types: Cell Culture Supernates
  118. Resveratrol reverses the adverse effects of bevacizumab on cultured ARPE-19 cells
    Authors: M Subramani, M Ponnalagu, L Krishna, N Jeyabalan, P Chevour, A Sharma, C Jayadev, R Shetty, N Begum, G Archunan, D Das
    Sci Rep, 2017-09-25;7(1):12242.
    Species: Human
    Sample Types: Cell Culture Supernates
  119. The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors
    Authors: J Miku?a-Pie, P Uruski, S Szubert, K Maksin, R Moszy?ski, D Szpurek, A Wo?niak, S Sajdak, A Tykarski, K Ksi??ek
    Biomed Res Int, 2017-09-20;2017(0):2592496.
    Species: Human
    Sample Types: Cell Culture Supernates
  120. Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of Pterygia
    Authors: Q Meng, Y Qin, M Deshpande, F Kashiwabuc, M Rodrigues, Q Lu, H Ren, JH Elisseeff, GL Semenza, SV Montaner, A Sodhi
    Invest. Ophthalmol. Vis. Sci., 2017-09-01;58(11):4514-4523.
    Species: Human
    Sample Types: Cell Culture Supernates
  121. Tumor microenvironment conditions alter Akt and Na(+)/H(+) exchanger NHE1 expression in endothelial cells more than hypoxia alone: implications for endothelial cell function in cancer
    Authors: AK Pedersen, J Mendes Lop, N Mørup, K Tritsaris, SF Pedersen
    BMC Cancer, 2017-08-14;17(1):542.
    Species: Human
    Sample Types: Cell Culture Supernates
  122. Minocycline modulates NF?B phosphorylation and enhances antimicrobial activity against Staphylococcus aureus in mesenchymal stromal/stem cells
    Authors: AD Guerra, WE Rose, P Hematti, WJ Kao
    Stem Cell Res Ther, 2017-07-21;8(1):171.
    Species: Human
    Sample Types: Cell Culture Supernates
  123. A combination of platelet features allows detection of early-stage cancer
    Authors: S Sabrkhany, MJE Kuijpers, SMJ van Kuijk, L Sanders, S Pineda, SWM Olde Damin, AC Dingemans, AW Griffioen, MGA Oude Egbri
    Eur. J. Cancer, 2017-05-17;80(0):5-13.
    Species: Human
    Sample Types: Platelets
  124. Deletion of lactate dehydrogenase-A in myeloid cells triggers antitumor immunity
    Authors: P Seth, E Csizmadia, A Hedblom, M Vuerich, H Xie, M Li, MS Longhi, B Wegiel
    Cancer Res., 2017-04-26;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  125. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017-04-17;8(1):79.
    Species: Human
    Sample Types: Cell Culture Supernates
  126. Methoxyluteolin Inhibits Neuropeptide-stimulated Proinflammatory Mediator Release via mTOR Activation from Human Mast Cells.
    Authors: Patel A, Theoharides T
    J Pharmacol Exp Ther, 2017-04-12;361(3):462-471.
    Species: Human
    Sample Types: Cell Culture Supernates
  127. Gelatin device for the delivery of growth factors involved in endochondral ossification
    Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
    PLoS ONE, 2017-04-05;12(4):e0175095.
    Species: Chicken, Human
    Sample Types: Cell Culture Supernates, Recombinant Protein
  128. Effect of 2-octylcyanoacrylate on placenta derived mesenchymal stromal cells on extracellular matrix
    Authors: YJ Chen, L Lankford, S Kabagambe, Z Saenz, P Kumar, D Farmer, A Wang
    Placenta, 2017-04-02;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  129. Is vascular endothelial growth factor a useful biomarker in giant cell arteritis?
    Authors: N Goodfellow, J Morlet, S Singh, A Sabokbar, A Hutchings, V Sharma, J Vaskova, S Masters, A Zarei, R Luqmani
    RMD Open, 2017-03-29;3(1):e000353.
    Species: Human
    Sample Types: Serum
  130. Reduction of relative centrifugal forces increases growth factor release within solid platelet-rich-fibrin (PRF)-based matrices: a proof of concept of LSCC (low speed centrifugation concept)
    Authors: K El Bagdadi, A Kubesch, X Yu, S Al-Maawi, A Orlowska, A Dias, P Booms, E Dohle, R Sader, CJ Kirkpatric, J Choukroun, S Ghanaati
    Eur J Trauma Emerg Surg, 2017-03-21;0(0):.
    Species: Human
    Sample Types: Complex Sample Type
  131. Mechanisms regulating angiogenesis underlie seasonal control of pituitary function
    Authors: J Castle-Mil, DO Bates, DJ Tortonese
    Proc. Natl. Acad. Sci. U.S.A, 2017-03-07;114(12):E2514-E2523.
    Species: Ovine
    Sample Types: Tissue Homogenates
  132. Effects of Ranibizumab and Aflibercept on Human M�ller Cells and Photoreceptors under Stress Conditions
    Authors: W Shen, B Yau, SR Lee, L Zhu, M Yam, MC Gillies
    Int J Mol Sci, 2017-03-01;18(3):.
    Species: Human
    Sample Types: Cell Culture Supernates
  133. Differential regulation of blood flow induced neovascularisation and mural cell recruitment by VEGF and angiopoietin signalling
    Authors: David O Bates
    J. Physiol. (Lond.), 2017-02-02;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
  134. Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells
    Authors: Gabriela Odent Grig
    J Tissue Eng Regen Med, 2016-12-12;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  135. Angiogenic proteins, placental weight and perinatal outcomes among pregnant women in Tanzania
    PLoS ONE, 2016-12-09;11(12):e0167716.
    Species: Human
    Sample Types: Plasma
  136. Delphinidin inhibits angiogenesis through the suppression of HIF-1? and VEGF expression in A549 lung cancer cells
    Oncol. Rep, 2016-12-07;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  137. Tuberculosis-diabetes co-morbidity is characterized by heightened systemic levels of circulating angiogenic factors.
    Authors: Kumar N, Moideen K, Sivakumar S, Menon P, Viswanathan V, Kornfeld H, Babu S
    J Infect, 2016-10-04;74(1):10-21.
    Species: Human
    Sample Types: Plasma
  138. Stand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells
    Sci Rep, 2016-09-01;6(0):32505.
    Applications: ChIP
  139. A functional bioassay to determine the activity of anti-VEGF antibody therapy in blood of patients with cancer
    Br J Cancer, 2016-08-30;0(0):.
    Species: Human
    Sample Types: Serum
  140. EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance
    Nat Commun, 2016-07-29;7(0):12329.
    Species: Human
    Sample Types: Cell Culture Supernates
  141. Effect of prostaglandin D2 on VEGF release by nasal polyp fibroblasts
    Authors: K Kanai, M Okano, T Fujiwara, S Kariya, T Haruna, R Omichi, SI Makihara, Y Hirata, K Nishizaki
    Allergol Int, 2016-04-16;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  142. Regulating VEGF signaling in platelet concentrates via specific VEGF sequestering
    Authors: DG Belair, NN Le, WL Murphy
    Biomater Sci, 2016-03-24;4(5):819-25.
    Species: Human
    Sample Types: Plasma
  143. Circulating Angiogenic Factors as Biomarkers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis.
    Authors: Kumar N, Banurekha V, Nair D, Babu S
    PLoS ONE, 2016-01-04;11(1):e0146318.
    Species: Human
    Sample Types: Plasma
  144. High-grade serous ovarian cancer cell lines exhibit heterogeneous responses to growth factor stimulation.
    Authors: Bourgeois D, Kabarowski K, Porubsky V, Kreeger P
    Cancer Cell Int, 2015-12-07;15(0):112.
    Species: Human
    Sample Types: Cell Culture Supernates
  145. Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-alpha.
    Authors: Aubin K, Safoine M, Proulx M, Audet-Casgrain M, Côté J, Tetu F, Roy A, Fradette J
    PLoS ONE, 2015-09-14;10(9):e0137612.
    Species: Human
    Sample Types: Cell Culture Supernates
  146. Inflammatory and Angiogenic Factors at Mid-Pregnancy Are Associated with Spontaneous Preterm Birth in a Cohort of Tanzanian Women.
    Authors: McDonald C, Darling A, Conroy A, Tran V, Cabrera A, Liles W, Wang M, Aboud S, Urassa W, Fawzi W, Kain K
    PLoS ONE, 2015-08-06;10(8):e0134619.
    Species: Human
    Sample Types: Plasma
  147. A method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput format.
    Authors: Hogg S, Evans J, Sykes P, Chitcholtan K
    J Ovarian Res, 2015-07-04;8(0):43.
    Species: Human
    Sample Types: Cell Culture Supernates
  148. Synchronous down-modulation of miR-17 family members is an early causative event in the retinal angiogenic switch.
    Authors: Nunes D, Dias-Neto E, Cardo-Vila M, Edwards J, Dobroff A, Giordano R, Mandelin J, Brentani H, Hasselgren C, Yao V, Marchio S, Pereira C, Passetti F, Calin G, Sidman R, Arap W, Pasqualini R
    Proc Natl Acad Sci U S A, 2015-03-09;112(12):3770-5.
    Species: Human
    Sample Types: Cell Culture Supernates
  149. Creating capillary networks within human engineered tissues: Impact of adipocytes and their secretory products
    Authors: Kim Aubin, Caroline Vincent, Maryse Proulx, Dominique Mayrand, Julie Fradette
    Acta Biomaterialia
    Species: Human
    Sample Types: Cell Culture Supernates
  150. The effect of nitrogen containing bisphosphonates, zoledronate and alendronate, on the production of pro-angiogenic factors by osteoblastic cells.
    Authors: Ishtiaq S, Edwards S, Sankaralingam A, Evans B, Elford C, Frost M, Fogelman I, Hampson G
    Cytokine, 2014-11-17;71(2):154-60.
    Species: Human
    Sample Types: Serum
  151. The radiosensitising effect of gemcitabine and its main metabolite dFdU under low oxygen conditions is in vitro not dependent on functional HIF-1 protein.
    Authors: Wouters A, Pauwels B, Burrows N, Baay M, Deschoolmeester V, Vu T, Laukens K, Meijnders P, Van Gestel D, Williams K, Van den Weyngaert D, Vermorken J, Pauwels P, Peeters M, Lardon F
    BMC Cancer, 2014-08-16;14(0):594.
    Species: Human
    Sample Types: Cell Culture Supernates
  152. The role of VEGF-A165b in trophoblast survival.
    Authors: Bills V, Hamdollah-Zadeh M, Soothill P, Harper S, Bates D
    BMC Pregnancy Childbirth, 2014-08-15;14(0):278.
    Species: Human
    Sample Types: Cell Lysates
  153. Targeting SRPK1 to control VEGF-mediated tumour angiogenesis in metastatic melanoma.
    Authors: Gammons, M V, Lucas, R, Dean, R, Coupland, S E, Oltean, S, Bates, D O
    Br J Cancer, 2014-07-10;111(3):477-85.
    Species: Human
    Sample Types: Cell Lysates
  154. Circulating autoantibodies to endothelial progenitor cells: binding characteristics and association with risk factors for atherosclerosis.
    Authors: George J, Matucci-Cerinic M, Bar I, Shimoni S
    PLoS ONE, 2014-06-19;9(6):e97836.
    Species: Human
    Sample Types: Serum
  155. Celastrol inhibits the HIF-1alpha pathway by inhibition of mTOR/p70S6K/eIF4E and ERK1/2 phosphorylation in human hepatoma cells.
    Authors: Ma J, Han L, Liang H, Mi C, Shi H, Lee J, Jin X
    Oncol Rep, 2014-05-23;32(1):235-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  156. Autocrine impact of VEGF-A on uveal melanoma cells.
    Authors: Koch K, Refaian N, Hos D, Schlereth S, Bosch J, Cursiefen C, Heindl L
    Invest Ophthalmol Vis Sci, 2014-04-25;55(4):2697-704.
    Species: Human
    Sample Types: Cell Culture Supernates
  157. Benefits of whole body vibration training in patients hospitalised for COPD exacerbations - a randomized clinical trial.
    Authors: Greulich T, Nell C, Koepke J, Fechtel J, Franke M, Schmeck B, Haid D, Apelt S, Filipovic S, Kenn K, Janciauskiene S, Vogelmeier C, Koczulla A
    BMC Pulm Med, 2014-04-11;14(0):60.
    Species: Human
    Sample Types: Serum
  158. hERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implications.
    Authors: Crociani O, Lastraioli E, Boni L, Pillozzi S, Romoli M, D'Amico M, Stefanini M, Crescioli S, Masi A, Taddei A, Bencini L, Bernini M, Farsi M, Beghelli S, Scarpa A, Messerini L, Tomezzoli A, Vindigni C, Morgagni P, Saragoni L, Giommoni E, Gasperoni S, Di Costanzo F, Roviello F, De Manzoni G, Bechi P, Arcangeli A
    Clin Cancer Res, 2014-01-21;20(6):1502-12.
    Species: Human
    Sample Types: Cell Culture Supernates
  159. Host biomarkers distinguish dengue from leptospirosis in Colombia: a case-control study.
    Authors: Conroy A, Gelvez M, Hawkes M, Rajwans N, Liles W, Villar-Centeno L, Kain K
    BMC Infect Dis, 2014-01-20;14(0):35.
    Species: Human
    Sample Types: Serum
  160. Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo.
    Authors: Shamis Y, Silva E, Hewitt K, Brudno Y, Levenberg S, Mooney D, Garlick J
    PLoS ONE, 2013-12-30;8(12):e83755.
    Species: Human
    Sample Types: Cell Culture Supernates
  161. IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer.
    Authors: Kachroo P, Lee M, Zhang L, Baratelli F, Lee G, Srivastava M, Wang G, Walser T, Krysan K, Sharma S, Dubinett S, Lee J
    J Exp Clin Cancer Res, 2013-11-25;32(0):97.
    Species: Human
    Sample Types: Cell Culture Supernates
  162. Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model.
    Authors: Kim, Kwang S, Lee, Hong J, An, Jin, Kim, Yun B, Ra, Jung Cha, Lim, Inja, Kim, Seung U
    Cell Transplant, 2013-09-18;23(12):1585-97.
    Species: Human
    Sample Types: Cell Culture Supernates
  163. Prognostic impact of PHIP copy number in melanoma: linkage to ulceration.
    Authors: Bezrookove, Vladimir, De Semir, David, Nosrati, Mehdi, Tong, Schuyler, Wu, Clayton, Thummala, Suresh, Dar, Altaf A, Leong, Stanley, Cleaver, James E, Sagebiel, Richard, Miller, James R, Kashani-Sabet, Mohammed
    J Invest Dermatol, 2013-09-04;134(3):783-90.
    Species: Human
    Sample Types: Cell Culture Supernates
  164. Fcgamma receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies.
    Authors: Justiniano S, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda J, Mo X, Cheney C, Hertlein E, Eubank T, Marsh C, Muthusamy N, Butchar J, Byrd J, Tridandapani S
    J Biol Chem, 2013-07-31;288(37):26800-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  165. Thrombin-cleaved fragments of osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage.
    Authors: Yamaguchi Y, Shao Z, Sharif S, Du X, Myles T, Merchant M, Harsh G, Glantz M, Recht L, Morser J, Leung L
    J Biol Chem, 2012-11-30;288(5):3097-111.
    Species: Human
    Sample Types: CSF
  166. Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma.
    J. Exp. Med., 2012-10-01;209(11):1985-2000.
    Species: Human
    Sample Types: Cell Culture Supernates
  167. Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma.
    Authors: Clifford RL, John AE, Brightling CE
    J. Immunol., 2012-06-11;189(2):819-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  168. Performance characteristics of combinations of host biomarkers to identify women with occult placental malaria: a case-control study from Malawi.
    Authors: Conroy AL, Liles WC, Molyneux ME
    PLoS ONE, 2011-12-12;6(12):e28540.
    Species: Human
    Sample Types: Plasma
  169. Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli.
    Authors: Chatterjee M, Huang Z, Zhang W, Jiang L, Hultenby K, Zhu L, Hu H, Nilsson GP, Li N
    Blood, 2011-02-17;117(14):3907-11.
    Species: Human
    Sample Types: Cell Culture Supernates
  170. Increased levels of plasma haemoxygenase-1 in prostate cancer.
    Authors: Blann AD, Balakrishnan B, Ryan P
    Prostate Cancer Prostatic Dis., 2011-01-25;14(2):114-7.
    Species: Human
    Sample Types: Plasma
  171. Endothelium-based biomarkers are associated with cerebral malaria in Malawian children: a retrospective case-control study.
    Authors: Conroy AL, Phiri H, Hawkes M, Glover S, Mallewa M, Seydel KB, Taylor TE, Molyneux ME, Kain KC
    PLoS ONE, 2010-12-29;5(12):e15291.
    Species: Human
    Sample Types: Plasma
  172. Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma.
    Authors: Ma T, Jham BC, Hu J
    Proc. Natl. Acad. Sci. U.S.A., 2010-07-26;107(32):14363-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  173. Normal ranges of angiogenesis regulatory proteins in human platelets.
    Authors: Peterson JE, Zurakowski D, Italiano JE
    Am. J. Hematol., 2010-07-01;85(7):487-93.
    Species: Human
    Sample Types: Cell Lysates
  174. Soluble forms of VEGF receptor-1 and -2 promote vascular maturation via mural cell recruitment.
    Authors: Lorquet S, Berndt S, Blacher S, Gengoux E, Peulen O, Maquoi E, Noel A, Foidart JM, Munaut C, Pequeux C
    FASEB J., 2010-05-19;24(10):3782-95.
    Species: Human
    Sample Types: Cell Lysates
  175. Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.
    Authors: Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Rentsenhand B, Makino H, Ranjan P, Minakuchi K, Sone S
    J. Immunol., 2009-12-15;183(12):8176-85.
    Species: Human
    Sample Types: Cell Culture Supernates
  176. The roles of Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell maturation state in osteogenesis on microstructured titanium surfaces.
    Authors: Olivares-Navarrete R, Hyzy S, Wieland M, Boyan BD, Schwartz Z
    Biomaterials, 2009-12-09;31(8):2015-24.
    Species: Human
    Sample Types: Cell Lysates
  177. VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo.
    Authors: Rennel ES, Varey AH, Churchill AJ, Wheatley ER, Stewart L, Mather S, Bates DO, Harper SJ
    Br. J. Cancer, 2009-08-25;101(7):1183-93.
    Species: Human
    Sample Types: Cell Culture Supernates
  178. Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer.
    Authors: Boneberg EM, Legler DF, Hoefer MM, Ohlschlegel C, Steininger H, Fuzesi L, Beer GM, Dupont-Lampert V, Otto F, Senn HJ, Furstenberger G
    Br. J. Cancer, 2009-08-18;101(4):605-14.
    Species: Human
    Sample Types: Serum
  179. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages.
    Authors: Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, Ponsoda S, Delneste Y, Hebbar M, Jeannin P
    Int. J. Cancer, 2009-07-15;125(2):367-73.
    Species: Human
    Sample Types: Cell Culture Supernates
  180. Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction.
    Authors: Korf-Klingebiel M, Kempf T, Sauer T, Brinkmann E, Fischer P, Meyer GP, Ganser A, Drexler H, Wollert KC
    Eur. Heart J., 2008-10-25;29(23):2851-8.
    Species: Human
    Sample Types: Cell Culture Supernates
  181. Serum levels of angiogenic factors and their prognostic relevance in bladder cancer.
    Authors: Szarvas T, Jager T, Droste F, Becker M, Kovalszky I, Romics I, Ergun S, Rubben H
    Pathol. Oncol. Res., 2008-09-20;15(2):193-201.
    Species: Human
    Sample Types: Serum
  182. Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.
    Authors: Ahmed S, Marotte H, Kwan K, Ruth JH, Campbell PL, Rabquer BJ, Pakozdi A, Koch AE
    Proc. Natl. Acad. Sci. U.S.A., 2008-09-16;105(38):14692-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  183. Adenosine receptors in regulation of dendritic cell differentiation and function.
    Authors: Novitskiy SV, Ryzhov S, Zaynagetdinov R, Goldstein AE, Huang Y, Tikhomirov OY, Blackburn MR, Biaggioni I, Carbone DP, Feoktistov I, Dikov MM
    Blood, 2008-06-17;112(5):1822-31.
    Species: Human
    Sample Types: Cell Culture Supernates
  184. Lipopolysaccharide-squamous cell carcinoma-monocyte interactions induce cancer-supporting factors leading to rapid STAT3 activation.
    Authors: Kurago ZB, Lam-ubol A, Stetsenko A
    Head Neck Pathol, 2008-03-01;2(1):1-12.
    Species: Human
    Sample Types: Cell Culture Supernates
  185. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.
    Authors: Duluc D, Delneste Y, Tan F, Moles MP, Grimaud L, Lenoir J, Preisser L, Anegon I, Catala L, Ifrah N, Descamps P, Gamelin E, Gascan H, Hebbar M, Jeannin P
    Blood, 2007-09-11;110(13):4319-30.
    Species: Human
    Sample Types: Cell Culture Supernates
  186. Angiogenesis markers (VEGF, soluble receptor of VEGF and angiopoietin-1) in very early arthritis and their association with inflammation and joint destruction.
    Authors: Clavel G, Bessis N, Lemeiter D, Fardellone P, Mejjad O, Menard JF, Pouplin S, Boumier P, Vittecoq O, Le Loet X, Boissier MC
    Clin. Immunol., 2007-06-08;124(2):158-64.
    Species: Human
    Sample Types: Serum
  187. Pretreatment serum endostatin as a prognostic indicator in metastatic gastric carcinoma.
    Authors: Woo IS, Kim KA, Jeon HM, Hong SH, Rho SY, Koh SJ, Lee MA, Byun JH, Kang JH, Hong YS, Lee KS, Cho CS, Choi MG, Chung IS
    Int. J. Cancer, 2006-12-15;119(12):2901-6.
    Species: Human
    Sample Types: Serum
  188. The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: potential steroid-sparing role for DHEA.
    Authors: Harding G, Mak YT, Evans B, Cheung J, MacDonald D, Hampson G
    Cytokine, 2006-12-11;36(1):57-68.
    Species: Human
    Sample Types: Cell Culture Supernates
  189. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term.
    Authors: Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, Hunter AJ, Soothill PW, Read M, Donaldson LF, Harper SJ
    Clin. Sci., 2006-05-01;110(5):575-85.
    Species: Human
    Sample Types: Tissue Homogenates
  190. Angiopoietin-2 levels are elevated in exudative pleural effusions.
    Authors: Kalomenidis I, Kollintza A, Sigala I, Papapetropoulos A, Papiris S, Light RW, Roussos C
    Chest, 2006-05-01;129(5):1259-66.
    Species: Human
    Sample Types: Pleural Effusion
  191. Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer.
    Authors: Furstenberger G, von Moos R, Lucas R, Thurlimann B, Senn HJ, Hamacher J, Boneberg EM
    Br. J. Cancer, 2006-02-27;94(4):524-31.
    Species: Human
    Sample Types: Serum
  192. Vascular endothelial growth factor-D is a survival factor for human breast carcinoma cells.
    Authors: Akahane M, Akahane T, Matheny SL, Shah A, Okajima E, Thorgeirsson UP
    Int. J. Cancer, 2006-02-15;118(4):841-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  193. Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta.
    Authors: Li H, Gu B, Zhang Y, Lewis DF, Wang Y
    Placenta, 2005-02-01;26(2):210-7.
    Species: Human
    Sample Types: Cell Culture Supernates
  194. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.
    Authors: Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB
    Immunity, 2004-12-01;21(6):831-42.
    Species: Human
    Sample Types: Cell Culture Supernates
  195. Increased circulating hematopoietic and endothelial progenitor cells in the early phase of acute myocardial infarction.
    Authors: Massa M, Rosti V, Ferrario M, Campanelli R, Ramajoli I, Rosso R, De Ferrari GM, Ferlini M, Goffredo L, Bertoletti A, Klersy C, Pecci A, Moratti R, Tavazzi L
    Blood, 2004-09-02;105(1):199-206.
    Species: Human
    Sample Types: Plasma

FAQs

  1. What forms of VEGF does Human VEGF DuoSet ELISA (Catalog # DY293B) detect?

    • The Human VEGF DuoSet ELISA, Catalog # DY293B, has been shown to recognize rhVEGF165, rhVEGF121, and rhVEGF165b. Additional information regarding our specificity testing can be found in the product datasheet. 

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Human VEGF DuoSet ELISA
By Gabriele Strusi on 11/21/2022
Sample Tested: HepG2 human hepatocellular carcinoma cell line,Human cell conditioned medium
Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Anonymous on 05/12/2021
Sample Tested: Cell culture supernatant
Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Carmen Martin-Ruiz on 08/14/2019
Sample Tested: Brain tissue,Human brain tissue homogeneate

Straight forward protocol, used on human tissue homogeneates on a 384-well format with 450/550 correction.

Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Amnon Berger on 03/23/2019
Sample Tested: Cell culture supernatant

I use this kit to measure VEGFA levels in cell culture supernatant with very clear results. The standard curve is great and redundant.

Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Sophie Millar on 01/16/2019
Sample Tested: Cell Culture Media,Cell culture supernatant
Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Anonymous on 10/11/2018
Sample Tested: Cell culture supernatant
Human VEGF DuoSet ELISA
By Anonymous on 06/07/2018
Sample Tested: Cell culture medium samples,medium samples

Great kit, very easy to follow!

Human VEGF DuoSet ELISA
By Anonymous on 07/17/2017
Sample Tested: THP-1 human acute monocytic leukemia cell line
Human VEGF DuoSet ELISA
By Anonymous on 06/23/2017
Sample Tested: A549 human lung carcinoma cell line
Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Abby Sukarto on 05/03/2017
Sample Tested: Human tissue

The substrate incubation resulted in weak change of color and so longer incubation is required for human VEGF ELISA kit.

Human VEGF DuoSet ELISA
By Anonymous on 03/14/2017
Sample Tested: Various cell lines

VEGF quantification was performed onto various cell lines and data obtained is presented with the chart attached

Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Ricardo Rivera on 08/13/2016
Sample Tested: Cell culture supernatant
Human VEGF DuoSet ELISA DY293B
Human VEGF DuoSet ELISA
By Anonymous on 05/23/2016
Sample Tested: Various cell lines were cultured and supernatant obtained to study time course VEGF secretion,Various cell lines
Human VEGF DuoSet ELISA DY293B