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Kynurenic acid sodium salt

Catalog #: 3694
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3694/100
Kynurenic acid sodium salt | CAS No. 2439-02-3 | iGluR Antagonists
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Description: Sodium salt of kynurenic acid (Cat. No. 0223)

Chemical Name: 4-Hydroxyquinoline-2-carboxylic acid sodium salt

Purity: ≥98%

Product Details
Citations (2)
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Biological Activity

Kynurenic acid sodium salt is a sodium salt of kynurenic acid (Cat. No. 0223), a broad spectrum EAA antagonist.

Technical Data

M.Wt:
211.15
Formula:
C10H6NNaO3
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
2439-02-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.
    Wang J, Simonavicius N, Wu X et al.
    J Biol Chem.
  2. An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid.
    Perkins and Stone
    Brain Res., 1982;247:184
  3. The 'kynurenate test', a biochemical assay for putative cognition enhancers.
    Pittaluga et al.
    J.Pharmacol.Exp.Ther., 1997;283:82
  4. NMDA receptors and ligands in the vertebrate CNS.
    Stone and Burton
    Prog.Neurobiol., 1988;30:333
  5. Brainstem activation of GABAB receptors in the nucleus tractus solitarius increases gastric motility
    L Bellusci, E Kim, S Garcia DuB, RA Gillis, S Vicini, N Sahibzada
    Frontiers in Neuroscience, 2022;16(0):961042.

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Citations for Kynurenic acid sodium salt

The citations listed below are publications that use Tocris products. Selected citations for Kynurenic acid sodium salt include:

2 Citations: Showing 1 - 2

  1. Brainstem activation of GABAB receptors in the nucleus tractus solitarius increases gastric motility.
    Authors: Stefano Et al.
    Front Neurosci  2022;16:961042
  2. Long-Range GABAergic Inhibition Modulates Spatiotemporal Dynamics of the Output Neurons in the Olfactory Bulb.
    Authors: Ruilong Et al.
    J Neurosci  2021;41:3610-3621

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