L-CCG-l
Chemical Name: (2S,1'S,2'S)-2-(Carboxycyclopropyl)glycine
Purity: ≥99%
Biological Activity
L-CCG-l is a potent group II metabotropic glutamate receptor agonist. More active than glutamate or (±)-trans-ACPD (Cat. No. 0187).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Comparative effect of L-CCG-I, DCG-IV and γ-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes.
Brabet et al.
Neuropharmacology, 1998;37:1043 -
Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells.
Hayashi et al.
Br.J.Pharmacol., 1992;107:539 -
Potent NMDA-like actions and potentiation of glutamate responses by conformational variants of a glutamate analogue in the rat spinal cord.
Shinozaki et al.
Br.J.Pharmacol., 1989;98:1213 -
Differentiation of group 2 and group 3 metabotropic glutamate receptor cAMP responses in the rat hippocampus.
Wright and Schoepp
Eur.J.Pharmacol., 1996;297:275
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citations for L-CCG-l
The citations listed below are publications that use Tocris products. Selected citations for L-CCG-l include:
4 Citations: Showing 1 - 4
-
HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.
Authors: Scholler
Nat Chem Biol 2017;13(4):372
-
Alleviation of kainic acid-induced brain barrier dysfunction by 4-o-methylhonokiol in in vitro and in vivo models.
Authors: Han Et al.
Biomed Res Int 2015;2015:893163
-
Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses.
Authors: Caiati Et al.
Sci Rep 2012;2:285
-
Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors.
Authors: Ster Et al.
Neuron 2011;108:9993
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for L-CCG-l
There are currently no reviews for this product. Be the first to review L-CCG-l and earn rewards!
Have you used L-CCG-l?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
