Mouse Lipocalin-2/NGAL DuoSet ELISA

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DY1857
DY1857-05
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Mouse Lipocalin-2 / NGAL ELISA Standard Curve
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Mouse Lipocalin-2/NGAL DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
7.8 - 500 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse Lipocalin-2. The suggested diluent is suitable for the analysis of most cell culture supernate, serum, and plasma samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

 

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

Scientific Data

Mouse Lipocalin-2 / NGAL ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Lipocalin-2/NGAL

The Lipocalin family comprises a diverse group of mostly secreted soluble proteins that bind hydrophobic ligands and act as transporters, carrying small molecules to specific cells. Lipocalins are related by possessing an 8-stranded beta-barrel structure. Lipocalin-1, also named tear lipocalin (TL), von Ebners gland protein (VEG) and tear pre-albumin, binds a large number of hydrophobic molecules and exhibits cysteine proteinase inhibitor and endonuclear activities. Lipocalin-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), is a component of granules in neutrophils from tissues that are normally exposed to microorganisms and is upregulated during inflammation. Lipocalin-2 can form homodimers and can heterodimerize with the neutrophil gelatinase MMP-9.

Long Name:
Neutrophil Gelatinase-associated Lipocalin
Entrez Gene IDs:
3934 (Human); 16819 (Mouse); 170496 (Rat); 102137149 (Cynomolgus Monkey)
Alternate Names:
24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; HNL; LCN2; lipocalin 2 (oncogene 24p3); lipocalin 2; Lipocalin2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; NGALlipocalin-2; Oncogene 24p3; p25; Siderocalin; Uterocalin

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

 

Citations for Mouse Lipocalin-2/NGAL DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

133 Citations: Showing 1 - 10
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  1. Postnatal supplementation with alarmins S100a8/a9 ameliorates malnutrition-induced neonate enteropathy in mice
    Authors: Perruzza, L;Heckmann, J;Rezzonico Jost, T;Raneri, M;Guglielmetti, S;Gargari, G;Palatella, M;Willers, M;Fehlhaber, B;Werlein, C;Vogl, T;Roth, J;Grassi, F;Viemann, D;
    Nature communications
    Species: Mouse
    Sample Types: Serum, Feces
  2. Select gut microbiota impede rotavirus vaccine efficacy
    Authors: Ngo, VL;Wang, Y;Wang, Y;Shi, Z;Britton, R;Zou, J;Ramani, S;Jiang, B;Gewirtz, AT;
    Cellular and molecular gastroenterology and hepatology
    Species: Mouse
    Sample Types: Serum
  3. Salmonella Typhimurium exploits host polyamines for assembly of the type 3 secretion machinery
    Authors: Miki, T;Uemura, T;Kinoshita, M;Ami, Y;Ito, M;Okada, N;Furuchi, T;Kurihara, S;Haneda, T;Minamino, T;Kim, YG;
    PLoS biology
    Species: Mouse
    Sample Types: Fecal Extracts
  4. Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis
    Authors: Hammouri, D;Orwick, A;Doll, M;Vega, DS;Shah, PP;Clarke, CJ;Clem, B;Beverly, LJ;Siskind, LJ;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Plasma
  5. Harnessing intestinal tryptophan catabolism to relieve atherosclerosis in mice
    Authors: Chajadine, M;Laurans, L;Radecke, T;Mouttoulingam, N;Al-Rifai, R;Bacquer, E;Delaroque, C;Rytter, H;Bredon, M;Knosp, C;Vilar, J;Fontaine, C;Suffee, N;Vandestienne, M;Esposito, B;Dairou, J;Launay, JM;Callebert, J;Tedgui, A;Ait-Oufella, H;Sokol, H;Chassaing, B;Taleb, S;
    Nature communications
    Species: Mouse
    Sample Types: Feces
  6. Gut microbial factors predict disease severity in a mouse model of multiple sclerosis
    Authors: Steimle, A;Neumann, M;Grant, ET;Willieme, S;De Sciscio, A;Parrish, A;Ollert, M;Miyauchi, E;Soga, T;Fukuda, S;Ohno, H;Desai, MS;
    Nature microbiology
    Species: Transgenic Mouse
    Sample Types: Fecal Extract
  7. Preclinical and clinical evidence of the association of colibactin-producing Escherichia coli with anxiety and depression in colon cancer
    Authors: Rondepierre, F;Meynier, M;Gagniere, J;Deneuvy, V;Deneuvy, A;Roche, G;Baudu, E;Pereira, B;Bonnet, R;Barnich, N;Carvalho, FA;Pezet, D;Bonnet, M;Jalenques, I;
    World journal of gastroenterology
    Species: Mouse
    Sample Types: Fecal Extract
  8. Commensal E. coli limits Salmonella gut invasion during inflammation by producing toxin-bound siderophores in a tonB-dependent manner
    Authors: Cherrak, Y;Salazar, MA;Yilmaz, K;Kreuzer, M;Hardt, WD;
    PLoS biology
    Species: Mouse
    Sample Types: Feces
  9. Further Evaluation of Enterohemorrhagic Escherichia coli Gold Nanoparticle Vaccines Utilizing Citrobacter rodentium as the Model Organism
    Authors: Bowser, S;Melton-Celsa, A;Chapartegui-González, I;Torres, AG;
    Vaccines
    Species: Mouse
    Sample Types: Feces
  10. Neutrophils and NADPH Oxidases Are Major Contributors to Mild but Not Severe Ischemic Acute Kidney Injury in Mice
    Authors: Révész, C;Kaucsár, T;Godó, M;Bocskai, K;Krenács, T;Mócsai, A;Szénási, G;Hamar, P;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Plasma
  11. Time resolved multi-omics reveals diverse metabolic strategies of Salmonella during diet-induced inflammation
    Authors: Kokkinias, K;Sabag-Daigle, A;Kim, Y;Leleiwi, I;Shaffer, M;Kevorkian, R;Daly, RA;Wysocki, VH;Borton, MA;Ahmer, BMM;Wrighton, KC;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Feces
  12. Evaluating the Effects of Chronic Oral Exposure to the Food Additive Silicon Dioxide on Oral Tolerance Induction and Food Sensitivities in Mice
    Authors: Lamas, B;Martins Breyner, N;Malaisé, Y;Wulczynski, M;Galipeau, HJ;Gaultier, E;Cartier, C;Verdu, EF;Houdeau, E;
    Environmental health perspectives
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. Optogenetic activation of cholinergic enteric neurons reduces inflammation in experimental colitis
    Authors: Rahman, AA;Stavely, R;Pan, W;Ott, L;Ohishi, K;Ohkura, T;Han, C;Hotta, R;Goldstein, AM;
    Cellular and molecular gastroenterology and hepatology
    Species: Mouse
    Sample Types: Fecal Extract
  14. Inflammatory Bowel Disease Increases the Severity of Myocardial Infarction after Acute Ischemia-Reperfusion Injury in Mice
    Authors: Mami, W;Znaidi-Marzouki, S;Doghri, R;Ben Ahmed, M;Znaidi, S;Messadi, E;
    Biomedicines
    Species: Mouse
    Sample Types: Feces
  15. Suppression of epithelial proliferation and tumorigenesis by immunoglobulin A
    Authors: Donaldson, GP;Reis, GL;Saad, M;Mamede, I;Chen, G;DelGaudio, NL;Zhang, D;Aydin, B;Harrer, CE;Castro, TB;Grivennikov, S;Reis, BS;Stadtmueller, BM;Victora, GD;Mucida, D;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Feces
  16. Prevention of Colitis-Associated Cancer via Oral Administration of M13-Loaded Lipid Nanoparticles
    Authors: Long, D;Alghoul, Z;Sung, J;Yang, C;Merlin, D;
    Pharmaceutics
    Species: Mouse
    Sample Types: Feces
  17. Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice
    Authors: Parrish, A;Boudaud, M;Grant, ET;Willieme, S;Neumann, M;Wolter, M;Craig, SZ;De Sciscio, A;Cosma, A;Hunewald, O;Ollert, M;Desai, MS;
    Nature microbiology
    Species: Mouse
    Sample Types: Fecal Supernates
  18. Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis
    Authors: Pham, HTT;Magez, S;Choi, B;Baatar, B;Jung, J;Radwanska, M;
    Nature communications
    Species: Mouse
    Sample Types: Plasma, Tissue Homogenates
  19. Vaccination against microbiota motility protects mice from the detrimental impact of dietary emulsifier consumption
    Authors: Kordahi, MC;Delaroque, C;Bredèche, MF;Gewirtz, AT;Chassaing, B;
    PLoS biology
    Species: Mouse
    Sample Types: Feces
  20. Nutritional and host environments determine community ecology and keystone species in a synthetic gut bacterial community
    Authors: Weiss, AS;Niedermeier, LS;von Strempel, A;Burrichter, AG;Ring, D;Meng, C;Kleigrewe, K;Lincetto, C;Hübner, J;Stecher, B;
    Nature communications
    Species: Mouse
    Sample Types: Feces
  21. Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice
    Authors: von Strempel, A;Weiss, AS;Wittmann, J;Salvado Silva, M;Ring, D;Wortmann, E;Clavel, T;Debarbieux, L;Kleigrewe, K;Stecher, B;
    PLoS pathogens
    Species: Mouse
    Sample Types: Feces
  22. Effects of Probiotics on Colitis-Induced Exacerbation of Alzheimer's Disease in AppNL-G-F Mice
    Authors: Sahu, B;Johnson, LM;Sohrabi, M;Usatii, AA;Craig, RMJ;Kaelberer, JB;Chandrasekaran, SP;Kaur, H;Nookala, S;Combs, CK;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates
  23. Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection
    Authors: Cortez, V;Livingston, B;Sharp, B;Hargest, V;Papizan, JB;Pedicino, N;Lanning, S;Vaughn Jordan, S;Gulman, J;Vogel, P;DuBois, RM;Chase Crawford, J;Boyd, DF;Pruett-Miller, SM;Thomas, PG;Schultz-Cherry, S;
    Mucosal immunology
    Species: Mouse
    Sample Types: Feces
  24. IL-36/IL-36R Signaling Promotes CD4+ T Cell-Dependent Colitis via Pro-Inflammatory Cytokine Production
    Authors: Maarouf, M;Kuczma, M;Denning, TL;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Fecal Supernates
  25. Gasdermin D independent canonical inflammasome responses cooperate with caspase-8 to establish host defense against gastrointestinal Citrobacter rodentium infection
    Authors: E Eeckhout, L Hamerlinck, V Jonckheere, P Van Damme, G van Loo, A Wullaert
    Cell Death & Disease, 2023-04-21;14(4):282.
    Species: Mouse
    Sample Types: Feces
  26. ATG16L1 protects from interferon-gamma-induced cell death in the small intestinal crypt
    Authors: EG Foerster, DKL Tsang, S Goyal, SJ Robertson, LM Robert, H Maughan, CJ Streutker, SE Girardin, DJ Philpott
    Mucosal Immunology, 2023-02-14;0(0):.
    Species: Transgenic Mouse
    Sample Types: Serum
  27. Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization
    Authors: KK Jang, T Heaney, M London, Y Ding, F Yeung, D Ercelen, YH Chen, J Axelrad, S Gurunathan, A Marijke Ke, ME Griffin, HC Hang, K Cadwell
    bioRxiv : the preprint server for biology, 2023-02-01;0(0):.
    Species: Mouse
    Sample Types: Stool Supernates
  28. Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut
    Authors: L Laganenka, JW Lee, L Malferthei, CL Dieterich, L Fuchs, J Piel, C von Mering, V Sourjik, WD Hardt
    Nature Microbiology, 2023-01-09;0(0):.
    Species: Mouse
    Sample Types: Feces
  29. Chronic gut inflammation impairs contextual control of fear
    Authors: CE Matisz, M Patel, NS Hong, RJ McDonald, AJ Gruber
    Scientific Reports, 2022-11-29;12(1):20586.
    Species: Mouse
    Sample Types: Feces
  30. Impact of Dextran-Sodium-Sulfate-Induced Enteritis on Murine Cytomegalovirus Reactivation
    Authors: A Jentzer, S Fauteux-Da, P Verhoeven, A Cantais, MY Novoa, F Jospin, B Chanut, N Rochereau, T Bourlet, X Roblin, B Pozzetto, S Pillet
    Viruses, 2022-11-22;14(12):.
    Species: Mouse
    Sample Types: Fecal Supernates
  31. Serpin-positive Bifidobacterium breve CNCM I-5644 improves intestinal permeability in two models of irritable bowel syndrome
    Authors: E Torres-Mar, S Holowacz, J Delannoy, L Lenoir, E Jacouton, S Gervason, M Meynier, AS Boucard, FA Carvalho, F Barbut, LG Bermúdez-H, P Langella, AJ Waligora-D
    Scientific Reports, 2022-11-17;12(1):19776.
    Species: Mouse
    Sample Types: Fecal Supernates
  32. Agr2-associated ER stress promotes adherent-invasive E.�coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis
    Authors: M Viladomiu, M Khounlotha, B Dogan, SF Lima, A Elsaadi, E Cardakli, JG Castellano, C Ng, J Herzog, AA Schoenborn, M Ellermann, B Liu, S Zhang, AS Gulati, RB Sartor, KW Simpson, SM Lipkin, RS Longman
    Cell Reports, 2022-11-15;41(7):111637.
    Species: Transgenic Mouse
    Sample Types: Feces
  33. Variant APOL1 protein in plasma associates with larger particles in humans and mouse models of kidney injury
    Authors: M Andrews, T Yoshida, CM Henderson, H Pflaum, A McGregor, JA Lieberman, IH de Boer, T Vaisar, J Himmelfarb, B Kestenbaum, JY Chung, SM Hewitt, BA Santo, B Ginley, P Sarder, AZ Rosenberg, T Murakami, JB Kopp, Z Kuklenyik, AN Hoofnagle
    PLoS ONE, 2022-10-24;17(10):e0276649.
    Species: Transgenic Mouse
    Sample Types: Urine
  34. Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer
    Authors: HG Roweth, MW Malloy, GJ Goreczny, IC Becker, Q Guo, EA Mittendorf, JE Italiano, SS McAllister, EM Battinelli
    Science Advances, 2022-10-12;8(41):eabo5224.
    Species: Mouse
    Sample Types: Plasma
  35. Anti-infective bile acids bind and inactivate a Salmonella virulence regulator
    Authors: X Yang, KR Stein, HC Hang
    Nature Chemical Biology, 2022-09-29;0(0):.
    Species: Mouse
    Sample Types: Feces
  36. IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis
    Authors: N Millet, NV Solis, D Aguilar, MS Lionakis, RT Wheeler, N Jendzjowsk, M Swidergall
    Nature Communications, 2022-09-22;13(1):5545.
    Species: Mouse
    Sample Types: Serum
  37. Intestinal effect of faba bean fractions in WD-fed mice treated with low dose of DSS
    Authors: D Papoutsis, SDC Rocha, AM Herfindal, S Kjølsrud B, H Carlsen
    PLoS ONE, 2022-08-08;17(8):e0272288.
    Species: Mouse
    Sample Types: Fecal Extracts
  38. Iron deficient diets modify the gut microbiome and reduce the severity of enteric infection in a mouse model of S. Typhimurium-induced enterocolitis
    Authors: JR Ippolito, BD Piccolo, MS Robeson, DE Barney, J Ali, P Singh, SR Hennigar
    The Journal of nutritional biochemistry, 2022-05-21;0(0):109065.
    Species: Mouse
    Sample Types: Plasma
  39. Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut
    Authors: Y Yoshimatsu, T Sujino, K Miyamoto, Y Harada, S Tanemoto, K Ono, S Umeda, K Yoshida, T Teratani, T Suzuki, Y Mikami, N Nakamoto, N Sasaki, K Takabayash, N Hosoe, H Ogata, K Sawada, T Imamura, A Yoshimura, T Kanai
    Cell Reports, 2022-05-10;39(6):110773.
    Species: Mouse
    Sample Types:
  40. The expression of virulence genes increases membrane permeability and sensitivity to envelope stress in Salmonella Typhimurium
    Authors: M Sobota, PN Rodilla Ra, A Cambré, A Rocker, J Mortier, T Gervais, T Haas, D Cornillet, D Chauvin, I Hug, T Julou, A Aertsen, M Diard
    PloS Biology, 2022-04-07;20(4):e3001608.
    Species: Mouse
    Sample Types: Fecal
  41. Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection
    Authors: R Sun, X Gu, C Lei, L Chen, S Chu, G Xu, MA Doll, Y Tan, W Feng, L Siskind, CJ McClain, Z Deng
    Cell Reports, 2022-03-29;38(13):110560.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  42. Development of spirulina for the manufacture and oral delivery of protein therapeutics
    Authors: BW Jester, H Zhao, M Gewe, T Adame, L Perruzza, DT Bolick, J Agosti, N Khuong, R Kuestner, C Gamble, K Cruickshan, J Ferrara, R Lim, T Paddock, C Brady, S Ertel, M Zhang, A Pollock, J Lee, J Xiong, M Tasch, T Saveria, D Doughty, J Marshall, D Carrieri, L Goetsch, J Dang, N Sanjaya, D Fletcher, A Martinez, B Kaldis, K Sigmar, E Afreen, T Nguyen, A Randolph, A Taber, A Krzeszowsk, B Robinett, DB Volkin, F Grassi, R Guerrant, R Takeuchi, B Finrow, C Behnke, J Roberts
    Nature Biotechnology, 2022-03-21;0(0):.
    Species: Mouse
    Sample Types: Fecal Supernates
  43. Colitis-associated microbiota drives changes in behaviour in male mice in the absence of inflammation
    Authors: FA Vicentini, JC Szamosi, L Rossi, L Griffin, K Nieves, D Bihan, IA Lewis, QJ Pittman, MG Swain, MG Surette, SA Hirota, KA Sharkey
    Brain, Behavior, and Immunity, 2022-03-05;102(0):266-278.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  44. Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis
    Authors: S Olivier, H Diounou, C Pochard, L Frechin, E Durieu, M Foretz, M Neunlist, M Rolli-Derk, B Viollet
    Cells, 2022-02-09;11(4):.
    Species: Mouse
    Sample Types: Feces
  45. Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity
    Authors: RH Mills, PS Dulai, Y Vázquez-Ba, C Sauceda, N Daniel, RR Gerner, LE Batachari, M Malfavon, Q Zhu, K Weldon, G Humphrey, M Carrillo-T, LD Goldasich, M Bryant, M Raffatellu, RA Quinn, AT Gewirtz, B Chassaing, H Chu, WJ Sandborn, PC Dorrestein, R Knight, DJ Gonzalez
    Nature Microbiology, 2022-01-27;7(2):262-276.
    Species: Mouse
    Sample Types: Fecal Supernates
  46. Closely related Salmonella Derby strains triggered distinct gut microbiota alteration
    Authors: X Yuan, H Xue, X Xu, X Jiao, Z Pan, Y Zhang
    Gut pathogens, 2022-01-25;14(1):6.
    Species: Mouse
    Sample Types: Serum
  47. Kidney tubule iron loading in experimental focal segmental glomerulosclerosis
    Authors: RPL van Swelm, S Beurskens, H Dijkman, ETG Wiegerinck, R Roelofs, F Thévenod, J van der Vl, JFM Wetzels, DW Swinkels, B Smeets
    Scientific Reports, 2022-01-24;12(1):1199.
    Species: Mouse
    Sample Types: Urine
  48. Streptozotocin-induced hyperglycemia alters the cecal metabolome and exacerbates antibiotic-induced dysbiosis
    Authors: JI Wurster, RL Peterson, CE Brown, S Penumutchu, DV Guzior, K Neugebauer, WH Sano, MM Sebastian, RA Quinn, P Belenky
    Cell Reports, 2021-12-14;37(11):110113.
    Species: Mouse
    Sample Types: Feces
  49. Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts
    Authors: CR Shaler, AA Parco, W Elhenawy, J Dourka, J Jury, EF Verdu, BK Coombes
    Nature Communications, 2021-11-18;12(1):6664.
    Species: Mouse
    Sample Types: Tissue Homogenates
  50. Tofacitinib-Induced Modulation of Intestinal Adaptive and Innate Immunity and Factors Driving Cellular and Systemic Pharmacokinetics
    Authors: B Texler, A Zollner, V Reinstadle, SJ Reider, S Macheiner, B Jelusic, A Pfister, C Watschinge, N Przysiecki, H Tilg, H Oberacher, AR Moschen
    Cellular and Molecular Gastroenterology and Hepatology, 2021-10-06;0(0):.
    Species: Mouse
    Sample Types: Feces
  51. Citrobacter amalonaticus Inhibits the Growth of Citrobacter rodentium in the Gut Lumen
    Authors: C Mullineaux, D Carson, EGD Hopkins, I Glegola-Ma, A Escobar-Ze, HP Browne, TD Lawley, G Frankel
    MBio, 2021-10-05;12(5):e0241021.
    Species: Mouse
    Sample Types: Feces
  52. mTOR signaling mediates ILC3-driven immunopathology
    Authors: C Teufel, E Horvath, A Peter, C Ercan, S Piscuoglio, MN Hall, D Finke, FM Lehmann
    Mucosal Immunology, 2021-08-02;0(0):.
    Species: Mouse
    Sample Types: Fecal Supernates
  53. Geographic differences in gut microbiota composition impact susceptibility to enteric infection
    Authors: AM Porras, Q Shi, H Zhou, R Callahan, G Montenegro, N Solomons, IL Brito
    Cell Reports, 2021-07-27;36(4):109457.
    Species: Mouse
    Sample Types: Stool Supernates
  54. Heteropolysaccharides from S. cerevisiae show anti-adhesive properties against E. coli associated with Crohn's disease
    Authors: A Sivignon, SY Yu, N Ballet, P Vandekerck, N Barnich, Y Guerardel
    Carbohydrate polymers, 2021-07-08;271(0):118415.
    Species: Mouse
    Sample Types: Fecal Supernates
  55. Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
    Authors: MC Andrews, CPM Duong, V Gopalakris, V Iebba, WS Chen, L Derosa, MAW Khan, AP Cogdill, MG White, MC Wong, G Ferrere, A Fluckiger, MP Roberti, P Opolon, MT Alou, S Yonekura, W Roh, CN Spencer, IF Curbelo, L Vence, A Reuben, S Johnson, R Arora, G Morad, M Lastrapes, EN Baruch, L Little, C Gumbs, ZA Cooper, PA Prieto, K Wani, AJ Lazar, MT Tetzlaff, CW Hudgens, MK Callahan, M Adamow, MA Postow, CE Ariyan, PO Gaudreau, L Nezi, D Raoult, C Mihalcioiu, A Elkrief, RC Pezo, LE Haydu, JM Simon, HA Tawbi, J McQuade, P Hwu, WJ Hwu, RN Amaria, EM Burton, SE Woodman, S Watowich, A Diab, SP Patel, IC Glitza, MK Wong, L Zhao, J Zhang, NJ Ajami, J Petrosino, RR Jenq, MA Davies, JE Gershenwal, PA Futreal, P Sharma, JP Allison, B Routy, L Zitvogel, JA Wargo
    Nature Medicine, 2021-07-08;0(0):.
    Species: Mouse
    Sample Types: Fecal Supernates
  56. Chronic cerebral lipocalin 2 exposure elicits hippocampal neuronal dysfunction and cognitive impairment
    Authors: B Olson, X Zhu, MA Norgard, P Diba, PR Levasseur, AC Buenafe, C Huisman, KG Burfeind, KA Michaelis, G Kong, T Braun, DL Marks
    Brain, Behavior, and Immunity, 2021-07-08;0(0):.
    Species: Mouse
    Sample Types: CSF
  57. NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation
    Authors: H Ahn, G Lee, J Kim, J Park, SG Kang, SI Yoon, E Lee, GS Lee
    Cells, 2021-07-02;10(7):.
    Species: Mouse
    Sample Types: Cell Lysates
  58. Intestinal Inflammation and Altered Gut Microbiota Associated with Inflammatory Bowel Disease Render Mice Susceptible to Clostridioides difficile Colonization and Infection
    Authors: L Abernathy-, MR Barron, JM George, MG Dieterle, KC Vendrov, IL Bergin, VB Young
    MBio, 2021-06-15;0(0):e0273320.
    Species: Mouse
    Sample Types: Feces
  59. Amino Acid-Based Diet Prevents Lethal Infectious Diarrhea by Maintaining Body Water Balance in a Murine Citrobacter rodentium Infection Model
    Authors: T Kimizuka, N Seki, G Yamaguchi, M Akiyama, S Higashi, K Hase, YG Kim
    Nutrients, 2021-05-31;13(6):.
    Species: Mouse
    Sample Types: Feces
  60. Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia
    Authors: B Olson, X Zhu, MA Norgard, PR Levasseur, JT Butler, A Buenafe, KG Burfeind, KA Michaelis, KR Pelz, H Mendez, J Edwards, SM Krasnow, AJ Grossberg, DL Marks
    Nature Communications, 2021-04-06;12(1):2057.
    Species: Mouse
    Sample Types: Plasma
  61. Western-style diet impedes colonization and clearance of Citrobacter rodentium
    Authors: J An, X Zhao, Y Wang, J Noriega, AT Gewirtz, J Zou
    PloS Pathogens, 2021-04-05;17(4):e1009497.
    Species: Mouse
    Sample Types: Fecal Supernates
  62. Consumption of Select Dietary Emulsifiers Exacerbates the Development of Spontaneous Intestinal Adenoma
    Authors: E Viennois, B Chassaing
    International Journal of Molecular Sciences, 2021-03-05;22(5):.
    Species: Mouse
    Sample Types: Faecal supernates
  63. Deletion of intestinal epithelial AMP-activated protein kinase alters distal colon permeability but not glucose homeostasis
    Authors: S Olivier, C Pochard, H Diounou, V Castillo, J Divoux, J Alcantara, J Leclerc, S Guilmeau, C Huet, W Charifi, TV Varin, N Daniel, M Foretz, M Neunlist, BL Salomon, P Ghosh, A Marette, M Rolli-Derk, B Viollet
    Molecular Metabolism, 2021-02-04;47(0):101183.
    Species: Mouse
    Sample Types: Fecal
  64. The impact of dextran sodium sulphate and probiotic pre-treatment in a murine model of Parkinson's disease
    Authors: Z Dwyer, M Chaiquin, J Landrigan, K Ayoub, P Shail, J Rocha, CL Childers, KB Storey, DJ Philpott, H Sun, S Hayley
    Journal of Neuroinflammation, 2021-01-09;18(1):20.
    Species: Mouse
    Sample Types: Plasma
  65. TNF Receptor 1 Promotes Early-Life Immunity and Protects against Colitis in Mice
    Authors: CY Liu, SS Tam, Y Huang, PE Dubé, R Alhosh, N Girish, S Punit, S Nataneli, F Li, JM Bender, MK Washington, DB Polk
    Cell Rep, 2020-10-20;33(3):108275.
    Species: Mouse
    Sample Types: Stool
  66. Lipopolysaccharide O structure of adherent and invasive Escherichia coli regulates intestinal inflammation via complement C3
    Authors: M Ohno, M Hasegawa, A Hayashi, G Caballero-, CJ Alteri, TD Lawley, N Kamada, G Núñez, N Inohara
    PLoS Pathog, 2020-10-07;16(10):e1008928.
    Species: Mouse
    Sample Types: Feces
  67. Dietary Emulsifiers Directly Impact Adherent-Invasive E.�coli Gene Expression to Drive Chronic Intestinal Inflammation
    Authors: E Viennois, A Bretin, PE Dubé, AC Maue, CJG Dauriat, N Barnich, AT Gewirtz, B Chassaing
    Cell Rep, 2020-10-06;33(1):108229.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  68. Targeting the gut to prevent sepsis from a cutaneous burn
    Authors: F Adiliaghda, P Cavallaro, V Mohad, M Almpani, F Kühn, MH Gharedaghi, M Najibi, LG Rahme, RA Hodin
    JCI Insight, 2020-10-02;5(19):.
    Species: Mouse
    Sample Types: Feces
  69. Dietary Fructose Alters the Composition, Localization and Metabolism of Gut Microbiota in Association with Worsening Colitis
    Authors: DC Montrose, R Nishiguchi, S Basu, HA Staab, XK Zhou, H Wang, L Meng, M Johncilla, JR Cubillos-R, DK Morales, MT Wells, KW Simpson, S Zhang, B Dogan, C Jiao, Z Fei, A Oka, JW Herzog, RB Sartor, AJ Dannenberg
    Cell Mol Gastroenterol Hepatol, 2020-09-20;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  70. In Vitro Characterization of Gut Microbiota-Derived Commensal Strains: Selection of Parabacteroides distasonis Strains Alleviating TNBS-Induced Colitis in Mice
    Authors: B Cuffaro, ALW Assohoun, D Boutillier, L Súkeníková, J Desramaut, S Boudebbouz, S Salomé-Des, J Hrdý, AJ Waligora-D, E Maguin, C Grangette
    Cells, 2020-09-16;9(9):.
    Species: Mouse
    Sample Types: Serum
  71. Lipocalin-2 deficiency may predispose to the progression of spontaneous age-related adiposity in mice
    Authors: K Meyers, M López, J Ho, S Wills, S Rayalam, S Taval
    Sci Rep, 2020-09-03;10(1):14589.
    Species: Mouse
    Sample Types: Serum
  72. Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis
    Authors: J Wu, Z Wei, P Cheng, C Qian, F Xu, Y Yang, A Wang, W Chen, Z Sun, Y Lu
    Theranostics, 2020-08-29;10(23):10665-10679.
    Species: Mouse
    Sample Types: Feces
  73. Identification of novel loci controlling inflammatory bowel disease susceptibility utilizing the genetic diversity of wild-derived mice
    Authors: KG Lahue, MK Lara, AA Linton, B Lavoie, Q Fang, MM McGill, JW Crothers, C Teuscher, GM Mawe, AL Tyler, JM Mahoney, DN Krementsov
    Genes Immun., 2020-08-26;0(0):.
    Species: Mouse
    Sample Types: Fecal Homogenate, Feces
  74. Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis
    Authors: EY Lin, HJ Lai, YK Cheng, KQ Leong, LC Cheng, YC Chou, YC Peng, YH Hsu, HS Chiang
    Biomedicines, 2020-08-05;8(8):.
    Species: Mouse
    Sample Types: Cell Lysates, Fecal Homogenates
  75. Methyl-donor supplementation prevents intestinal colonization by Adherent-Invasive E. coli in a mouse model of Crohn's disease
    Authors: E Gimier, M Chervy, A Agus, A Sivignon, E Billard, M Privat, S Viala, R Minet-Quin, A Buisson, E Vazeille, N Barnich, J Denizot
    Sci Rep, 2020-07-31;10(1):12922.
    Species: Mouse
    Sample Types: Cell Culture Supernates, Tissue Homogenates
  76. IFN-gamma promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b
    Authors: R Yang, H Huang, S Cui, Y Zhou, T Zhang, Y Zhou
    Cell Death Dis, 2020-07-30;11(7):603.
    Species: Mouse
    Sample Types: Serum
  77. Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation
    Authors: M Biagioli, A Carino, C Di Giorgio, S Marchianò, M Bordoni, R Roselli, E Distrutti, S Fiorucci
    Nutrients, 2020-06-30;12(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  78. Vitamin D Receptor Protects Against Dysbiosis and Tumorigenesis via the JAK/STAT Pathway in Intestine
    Authors: YG Zhang, R Lu, S Wu, I Chatterjee, D Zhou, Y Xia, J Sun
    Cell Mol Gastroenterol Hepatol, 2020-06-01;0(0):.
    Species: Mouse
    Sample Types: Fecal Homogenates
  79. Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation
    Authors: P Tod, EN Bukosza, B Róka, T Kaucsár, A Fintha, T Krenács, G Szénási, P Hamar
    Int J Mol Sci, 2020-05-28;21(11):.
    Species: Mouse
    Sample Types: Plasma
  80. Intestinal fungi are causally implicated in microbiome assembly and immune development in mice
    Authors: E van Tilbur, VK Pettersen, MW Gutierrez, I Laforest-L, NG Jendzjowsk, JB Cavin, FA Vicentini, CM Keenan, HR Ramay, J Samara, WK MacNaughto, RJA Wilson, MM Kelly, KD McCoy, KA Sharkey, MC Arrieta
    Nat Commun, 2020-05-22;11(1):2577.
    Species: Mouse
    Sample Types: Feces
  81. Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains
    Authors: P Saha, X Xiao, Y Li, RM Golonka, AA Abokor, BS Yeoh, M Vijay-Kuma
    Physiol Rep, 2020-05-01;8(9):e14441.
    Species: Mouse
    Sample Types: Serum
  82. Gut Microbiota Modulate CD8�T Cell Responses to Influence Colitis-Associated Tumorigenesis
    Authors: AI Yu, L Zhao, KA Eaton, S Ho, J Chen, S Poe, J Becker, A Gonzalez, D McKinstry, M Hasso, J Mendoza-Ca, J Whitfield, C Koumpouras, PD Schloss, EC Martens, GY Chen
    Cell Rep, 2020-04-07;31(1):107471.
    Species: Mouse
    Sample Types: Stool Homogenate
  83. Oral Administration of Heat-Treated Lactobacilli Modifies the Murine Microbiome and Reduces Citrobacter Induced Colitis
    Authors: AK Warda, PH de Almeida, CM Hueston, G Di Benedet, AG Clooney, C Hill
    Front Microbiol, 2020-01-30;11(0):69.
    Species: Mouse
    Sample Types: Feces
  84. Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling
    Authors: M Kumar, A Leon Coria, S Cornick, B Petri, S Mayengbam, HB Jijon, F Moreau, J Shearer, K Chadee
    Nat Commun, 2020-01-24;11(1):483.
    Species: Mouse
    Sample Types: Serum
  85. Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
    Authors: HQ Tran, RE Ley, AT Gewirtz, B Chassaing
    Nat Commun, 2019-12-11;10(1):5650.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  86. Chymase inhibition retards albuminuria in type 2 diabetes
    Authors: BJ Bivona, S Takai, DM Seth, R Satou, LM Harrison-B
    Physiol Rep, 2019-12-01;7(24):e14302.
    Species: Mouse
    Sample Types: Urine
  87. Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator
    Authors: DT Riglar, DL Richmond, L Potvin-Tro, AA Verdegaal, AD Naydich, S Bakshi, E Leoncini, LG Lyon, J Paulsson, PA Silver
    Nat Commun, 2019-10-11;10(1):4665.
    Species: Mouse
    Sample Types: Feces
  88. Std fimbriae-fucose interaction increases Salmonella-induced intestinal inflammation and prolongs colonization
    Authors: A Suwandi, A Galeev, R Riedel, S Sharma, K Seeger, T Sterzenbac, L García Pas, EC Boyle, O Gal-Mor, M Hensel, J Casadesús, JF Baines, GA Grassl
    PLoS Pathog., 2019-07-22;15(7):e1007915.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  89. Secretomes from metastatic breast cancer cells, enriched for a prognostically unfavorable LCN2 axis, induce anti-inflammatory MSC actions and a tumor-supportive premetastatic lung
    Authors: KJ Meade, F Sanchez, A Aguayo, N Nadales, SG Hamalian, TL Uhlendorf, LR Banner, JA Kelber
    Oncotarget, 2019-04-30;10(32):3027-3039.
    Species: Mouse
    Sample Types: Plasma
  90. Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection
    Authors: H Dubois, F Sorgeloos, ST Sarvestani, L Martens, Y Saeys, JM Mackenzie, M Lamkanfi, G van Loo, I Goodfellow, A Wullaert
    PLoS Pathog., 2019-04-24;15(4):e1007709.
    Species: Mouse
    Sample Types: Feces
  91. Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2
    Authors: L Zhou, C Chu, F Teng, NJ Bessman, J Goc, EK Santosa, GG Putzel, H Kabata, JR Kelsen, RN Baldassano, MA Shah, RE Sockolow, E Vivier, G Eberl, KA Smith, GF Sonnenberg
    Nature, 2019-04-03;0(0):.
    Species: Mouse
    Sample Types: Feces
  92. Intestinal Epithelial Cells and the Microbiome Undergo Swift Reprogramming at the Inception of Colonic Citrobacter rodentium Infection
    Authors: EGD Hopkins, TI Roumelioti, C Mullineaux, JS Choudhary, G Frankel
    MBio, 2019-04-02;10(2):.
    Species: Mouse
    Sample Types: Feces
  93. Microbial Colonization Coordinates the Pathogenesis of a Klebsiella pneumoniae Infant Isolate
    Authors: JL Pope, Y Yang, RC Newsome, W Sun, X Sun, M Ukhanova, J Neu, JP Issa, V Mai, C Jobin
    Sci Rep, 2019-03-04;9(1):3380.
    Species: Mouse
    Sample Types: Feces
  94. PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium
    Authors: P Saha, BS Yeoh, X Xiao, RM Golonka, V Singh, Y Wang, M Vijay-Kuma
    Mucosal Immunol, 2019-02-01;0(0):.
    Species: Mouse
    Sample Types: Serum
  95. Disruption of Intestinal Homeostasis and Intestinal Microbiota During Experimental Autoimmune Uveitis
    Authors: C Janowitz, YK Nakamura, C Metea, A Gligor, W Yu, L Karstens, JT Rosenbaum, M Asquith, P Lin
    Invest. Ophthalmol. Vis. Sci., 2019-01-02;60(1):420-429.
    Species: Mouse
    Sample Types: Feces
  96. The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses
    Authors: CN Berger, VF Crepin, TI Roumelioti, JC Wright, N Serafini, M Pevsner-Fi, L Yu, E Elinav, JP Di Santo, JS Choudhary, G Frankel
    PLoS Pathog., 2018-10-26;14(10):e1007406.
    Species: Mouse
    Sample Types: Feces
  97. The Food Additive Maltodextrin Promotes Endoplasmic Reticulum Stress-Driven Mucus Depletion and Exacerbates Intestinal Inflammation
    Authors: F Laudisi, D Di Fusco, V Dinallo, C Stolfi, A Di Grazia, I Marafini, A Colantoni, A Ortenzi, C Alteri, F Guerrieri, M Mavilio, F Ceccherini, M Federici, TT MacDonald, I Monteleone, G Monteleone
    Cell Mol Gastroenterol Hepatol, 2018-09-11;7(2):457-473.
    Species: Mouse
    Sample Types: Feces
  98. Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects
    Authors: X Xiao, P Saha, BS Yeoh, JA Hipp, V Singh, M Vijay-Kuma
    J. Nutr. Biochem., 2018-08-21;62(0):28-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  99. Genetic Ablation of Butyrate Utilization Attenuates Gastrointestinal Salmonella Disease
    Authors: DN Bronner, F Faber, EE Olsan, MX Byndloss, NA Sayed, G Xu, W Yoo, D Kim, S Ryu, CB Lebrilla, AJ Bäumler
    Cell Host Microbe, 2018-02-14;23(2):266-273.e4.
    Species: Mouse
    Sample Types: Feces
  100. Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota
    Authors: HT Groves, L Cuthbertso, P James, MF Moffatt, MJ Cox, JS Tregoning
    Front Immunol, 2018-02-12;9(0):182.
    Species: Mouse
    Sample Types: Feces
  101. Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice
    Authors: AF Schulfer, T Battaglia, Y Alvarez, L Bijnens, VE Ruiz, M Ho, S Robinson, T Ward, LM Cox, AB Rogers, D Knights, RB Sartor, MJ Blaser
    Nat Microbiol, 2017-11-27;0(0):.
    Species: Mouse
    Sample Types: Feces
  102. RNA Nanotherapeutics for the Amelioration of Astroglial Reactivity
    Authors: JA Smith, A Braga, J Verheyen, S Basilico, S Bandiera, C Alfaro-Cer, L Peruzzotti, D Shu, F Haque, P Guo, S Pluchino
    Mol Ther Nucleic Acids, 2017-11-24;10(0):103-121.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  103. The ESRP1-GPR137 axis contributes to intestinal pathogenesis
    Authors: LF Mager, VH Koelzer, R Stuber, L Thoo, I Keller, I Koeck, M Langenegge, C Simillion, SP Pfister, M Faderl, V Genitsch, I Tcymbarevi, P Juillerat, X Li, Y Xia, E Karamitopo, R Lyck, I Zlobec, S Hapfelmeie, R Bruggmann, KD McCoy, AJ Macpherson, C Müller, B Beutler, P Krebs
    Elife, 2017-10-04;6(0):.
    Species: Mouse
    Sample Types: Feces
  104. Isothiocyanate-enriched moringa seed extract alleviates ulcerative colitis symptoms in mice
    Authors: Y Kim, AG Wu, A Jaja-Chime, BL Graf, C Waterman, MP Verzi, I Raskin
    PLoS ONE, 2017-09-18;12(9):e0184709.
    Species: Mouse
    Sample Types: Feces
  105. Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
    Authors: K Watanabe, CA Gilchrist, MJ Uddin, SL Burgess, MM Abhyankar, SN Moonah, Z Noor, JR Donowitz, BN Schneider, T Arju, E Ahmed, M Kabir, M Alam, R Haque, P Pramoonjag, B Mehrad, WA Petri
    PLoS Pathog., 2017-08-17;13(8):e1006513.
    Species: Mouse
    Sample Types: Feces
  106. Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling
    Authors: M Quiros, H Nishio, PA Neumann, D Siuda, JC Brazil, V Azcutia, R Hilgarth, MN O'Leary, V Garcia-Her, G Leoni, M Feng, G Bernal, H Williams, PH Dedhia, C Gerner-Smi, J Spence, CA Parkos, TL Denning, A Nusrat
    J. Clin. Invest., 2017-08-07;0(0):.
    Species: Mouse
    Sample Types: Feces
  107. Dietary Salt Exacerbates Experimental Colitis
    Authors: AL Tubbs, B Liu, TD Rogers, RB Sartor, EA Miao
    J. Immunol., 2017-06-21;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  108. Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation
    Authors: DT Riglar, TW Giessen, M Baym, SJ Kerns, MJ Niederhube, RT Bronson, JW Kotula, GK Gerber, JC Way, PA Silver
    Nat. Biotechnol., 2017-05-29;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  109. Chemical and pathogen-induced inflammation disrupt the murine intestinal microbiome
    Authors: MA Borton, A Sabag-Daig, J Wu, LM Solden, BS O'Banion, RA Daly, RA Wolfe, JF Gonzalez, VH Wysocki, BMM Ahmer, KC Wrighton
    Microbiome, 2017-04-27;5(1):47.
    Species: Mouse
    Sample Types: Feces
  110. Bacterial Siderophores Hijack Neutrophil Functions
    Authors: P Saha, BS Yeoh, RA Olvera, X Xiao, V Singh, D Awasthi, BC Subramania, Q Chen, M Dikshit, Y Wang, CA Parent, M Vijay-Kuma
    J. Immunol., 2017-04-21;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  111. Experimental atopic dermatitis depends on IL-33R signaling via MyD88 in dendritic cells
    Authors: C Li, I Maillet, C Mackowiak, C Viala, F Di Padova, M Li, D Togbe, V Quesniaux, Y Lai, B Ryffel
    Cell Death Dis, 2017-04-06;8(4):e2735.
    Species: Mouse
    Sample Types: Tissue Homogenates
  112. Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and LPS-induced TLR4 signaling
    Authors: François Reichardt
    J. Physiol. (Lond.), 2017-02-08;0(0):.
    Species: Mouse
    Sample Types: Feces
  113. Combination Therapy for Ulcerative Colitis: Orally Targeted Nanoparticles Prevent Mucosal Damage and Relieve Inflammation
    Theranostics, 2016-09-25;6(12):2250-2266.
    Species: Mouse
    Sample Types: Feces
  114. Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis
    Cell Mol Gastroenterol Hepatol, 2016-07-01;2(4):482-498.e6.
    Species: Mouse
    Sample Types: Complex Sample Type
  115. Therapeutic Blockade of Immune Complex-Mediated Glomerulonephritis by Highly Selective Inhibition of Bruton's Tyrosine Kinase
    Sci Rep, 2016-05-19;6(0):26164.
    Species: Mouse
    Sample Types: Serum
  116. Pathogenic Upregulation of Glial Lipocalin-2 in the Parkinsonian Dopaminergic System
    J Neurosci, 2016-05-18;36(20):5608-22.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  117. Urine/Plasma Neutrophil Gelatinase Associated Lipocalin Ratio Is a Sensitive and Specific Marker of Subclinical Acute Kidney Injury in Mice.
    Authors: Kaucsar T, Godo M, Revesz C, Kovacs M, Mocsai A, Kiss N, Albert M, Krenacs T, Szenasi G, Hamar P
    PLoS ONE, 2016-01-29;11(1):e0148043.
    Species: Mouse
    Sample Types: Urine
  118. The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFDeltaARE Mice.
    Authors: Allais L, Kumar S, Debusschere K, Verschuere S, Maes T, De Smet R, Conickx G, De Vos M, Laukens D, Joos G, Brusselle G, Elewaut D, Cuvelier C, Bracke K
    PLoS ONE, 2015-11-02;10(11):e0141570.
    Species: Mouse
    Sample Types: Feces
  119. Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens.
    Authors: Kortman G, Mulder M, Richters T, Shanmugam N, Trebicka E, Boekhorst J, Timmerman H, Roelofs R, Wiegerinck E, Laarakkers C, Swinkels D, Bolhuis A, Cherayil B, Tjalsma H
    Eur J Immunol, 2015-06-23;45(9):2553-67.
    Species: Mouse
    Sample Types: Feces
  120. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.
    Authors: Chassaing, Benoit, Koren, Omry, Goodrich, Julia K, Poole, Angela C, Srinivasan, Shanthi, Ley, Ruth E, Gewirtz, Andrew T
    Nature, 2015-02-25;519(7541):92-6.
    Species: Mouse
    Sample Types: Feces
  121. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.
    Authors: Leoni, Giovanna, Neumann, Philipp-, Kamaly, Nazila, Quiros, Miguel, Nishio, Hikaru, Jones, Hefin R, Sumagin, Ronen, Hilgarth, Roland S, Alam, Ashfaqul, Fredman, Gabriell, Argyris, Ioannis, Rijcken, Emile, Kusters, Dennis, Reutelingsperger, Chris, Perretti, Mauro, Parkos, Charles, Farokhzad, Omid C, Neish, Andrew S, Nusrat, Asma
    J Clin Invest, 2015-02-09;125(3):1215-27.
    Species: Mouse
    Sample Types: Feces
  122. Dendritic cell-secreted lipocalin2 induces CD8+ T-cell apoptosis, contributes to T-cell priming and leads to a TH1 phenotype.
    Authors: Floderer M, Prchal-Murphy M, Vizzardelli C
    PLoS ONE, 2014-07-10;9(7):e101881.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  123. Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.
    Authors: Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R
    Infect Immun, 2014-06-23;82(9):3723-39.
    Species: Mouse
    Sample Types: Tissue Homogenates
  124. Rapid renal alpha-1 antitrypsin gene induction in experimental and clinical acute kidney injury.
    Authors: Zager R, Johnson A, Frostad K
    PLoS ONE, 2014-05-21;9(5):e98380.
    Species: Mouse
    Sample Types: Urine
  125. Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice.
    Authors: Shashidharamurthy R, Machiah D, Aitken J, Putty K, Srinivasan G, Chassaing B, Parkos C, Selvaraj P, Vijay-Kumar M
    Arthritis Rheum, 2013-04-01;65(4):1064-73.
    Species: Mouse
    Sample Types: Serum
  126. Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.
    PLoS ONE, 2012-09-05;7(9):e44328.
    Species: Mouse
    Sample Types: Feces
  127. Biomarkers of disease and treatment in murine and cynomolgus models of chronic asthma.
    Authors: Louten J, Mattson JD, Malinao MC, Li Y, Emson C, Vega F, Wardle RL, Van Scott MR, Fick RB, McClanahan TK, de Waal Malefyt R, Beaumont M
    Biomark Insights, 2012-07-10;7(0):87-104.
    Species: Mouse
    Sample Types: BALF
  128. The receptor of advanced glycation end products plays a central role in advanced oxidation protein products-induced podocyte apoptosis.
    Kidney Int, 2012-05-23;82(7):759-70.
    Species: Mouse
    Sample Types: Feces
  129. Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation.
    Authors: Ganguly K, Upadhyay S, Irmler M, Takenaka S, Pukelsheim K, Beckers J, de Angelis MH, Hamelmann E, Stoeger T, Schulz H
    Respir. Res., 2011-07-15;12(0):94.
    Species: Mouse
    Sample Types: BALF
  130. Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression.
    Authors: Pitteri SJ, Kelly-Spratt KS, Gurley KE
    Cancer Res., 2011-06-08;71(15):5090-100.
    Species: Mouse
    Sample Types: Plasma
  131. Plasma proteome profiles associated with inflammation, angiogenesis, and cancer.
    Authors: Kelly-Spratt KS, Pitteri SJ, Gurley KE, Liggitt D, Chin A, Kennedy J, Wong CH, Zhang Q, Buson TB, Wang H, Hanash SM, Kemp CJ
    PLoS ONE, 2011-05-12;6(5):e19721.
    Species: Mouse
    Sample Types: Plasma
  132. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.
    Authors: Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT
    Science, 2010-03-04;328(5975):228-31.
    Species: Mouse
    Sample Types: Serum
  133. Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.
    Authors: Pitteri SJ, JeBailey L, Faca VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM
    PLoS ONE, 2009-11-19;4(11):e7916.
    Species: Mouse
    Sample Types: Plasma

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Reviews for Mouse Lipocalin-2/NGAL DuoSet ELISA

Average Rating: 4.9 (Based on 9 Reviews)

5 Star
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4 Star
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Mouse Lipocalin-2/NGAL DuoSet ELISA
By Sangshan Tian on 02/08/2023
Sample Tested: Serum

Great kit as usual


Mouse Lipocalin-2/NGAL DuoSet ELISA
By Anonymous on 11/17/2022
Sample Tested: Urine

Great kit as usual. Always good results. We use 200x dilution for control samples and 200.000x dilution for AKI samples.


Mouse Lipocalin-2/NGAL DuoSet ELISA
By Anonymous on 09/14/2020
Sample Tested: Serum,Urine

Fantastic Duoset kit. Verified with Serum and Urine. For urine I ran 1:200 to 1:100 and for serum I ran 1:400 to 1:600 but once again it all depends on your individual samples. Acceptable CVs on all 5 plates that I ran.


Mouse Lipocalin-2/NGAL DuoSet ELISA
By Anonymous on 08/05/2020
Sample Tested: Frozen feces

Dilution of the standard was unclear
Everything else was fine


Mouse Lipocalin-2/NGAL DuoSet ELISA
By Anonymous on 03/06/2020
Sample Tested: Mouse feces

Mouse Lipocalin-2/NGAL DuoSet ELISA
By Anonymous on 01/14/2019
Sample Tested: frozen fecal sample

Mouse Lipocalin-2/NGAL DuoSet ELISA
By Anonymous on 12/07/2017
Sample Tested: Cell Culture Supernates,mouse serum,murine serum,murine tissue lysates

White Adipose Tissue (WAT) and Brown Adipose Tissue (BAT) lysates from wild-type mice.
500 ng total protein, 3-4 mice.


Mouse Lipocalin-2/NGAL DuoSet ELISA
By Anonymous on 04/21/2017
Sample Tested: Colon tissue

Mouse Lipocalin-2/NGAL DuoSet ELISA, 15 Plate
By Vishal Singh on 01/15/2016
Sample Tested: fecal extract,Serum

None: Every detail available with kit and very easy to use.