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Human/Mouse/Rat CD31/PECAM-1 Antibody

Catalog #: AF3628
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AF3628
AF3628-SP
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Detection of Mouse CD31/PECAM‑1 by Western Blot.
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Human/Mouse/Rat CD31/PECAM-1 Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human and mouse CD31/PECAM-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant porcine CD31 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CD31/PECAM-1
Glu18-Lys590
Accession # Q08481
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.5 µg/mL
U937 human histiocytic lymphoma cell line and bEnd.3 mouse endothelioma cell line 
Simple Western
10 µg/mL
bEnd.3 mouse endothelioma cell line
Flow Cytometry
0.25 µg/106 cells
Mouse and rat splenocytes, HUVEC cells, human whole blood granulocytes
Immunohistochemistry
3-15 µg/mL
Immersion fixed frozen sections of mouse embryo (13.5 d.p.c. and 14 d.p.c.), rat heart and immersion fixed paraffin-embedded sections of Human Placenta
CyTOF-ready
Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Immunocytochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Mouse CD31/PECAM-1 antibody by Western Blot. View Larger

Detection of Mouse CD31/PECAM‑1 by Western Blot. Western blot shows lysates of bEnd.3 mouse endothelioma cell line. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for CD31/PECAM-1 at approximately 130 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Simple Western View Larger

Detection of Mouse CD31/PECAM‑1 by Simple WesternTM. Simple Western shows lysates of bEnd.3 mouse endothelioma cell line, loaded at 0.5 mg/ml. A specific band was detected for CD31/PECAM‑1 at approximately 165 kDa (as indicated) using 10 µg/mL of Goat Anti-Human/Mouse/Rat CD31/PECAM‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628). This experiment was conducted under reducing conditions and using the 12-230kDa separation system.

Flow Cytometry Detection of CD31/PECAM-1 antibody in Mouse Splenocytes antibody by Flow Cytometry. View Larger

Detection of CD31/PECAM‑1 in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Human/Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628, filled histogram) or control antibody (AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (F0108).

Flow Cytometry Detection of CD31/PECAM-1 antibody in Rat Splenocytes antibody by Flow Cytometry. View Larger

Detection of CD31/PECAM‑1 in Rat Splenocytes by Flow Cytometry. Rat splenocytes were stained with Goat Anti-Human/Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628, filled histogram) or isotype control antibody (AB-108-C, open histogram), followed by Allophycocyanin-conjugated Anti-Goat IgG Secondary Antibody (F0108).

Immunocytochemistry CD31/PECAM-1 antibody in bEnd by Immunocytochemistry (ICC).3 Mouse Cell Line by Immunocytochemistry (ICC). View Larger

CD31/PECAM‑1 in bEnd.3 Mouse Cell Line. CD31/PECAM-1 was detected in immersion fixed bEnd.3 mouse endothelioma cell line using Goat Anti-Human/Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 493-conjugated Anti-Goat IgG Secondary Antibody (green; NL003) and counterstained with DAPI (blue). Specific staining was localized to cell membrane. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Immunohistochemistry CD31/PECAM-1 antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

CD31/PECAM‑1 in Mouse Embryo. CD31/PECAM-1 was detected in immersion fixed frozen sections of mouse embryo (E13.5) using Goat Anti-Human/Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 10 µg/mL overnight at 4 °C. Tissue was stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (yellow; NL001) and counterstained with DAPI (blue). Specific staining was localized to developing endothelium. View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections.

Immunohistochemistry CD31/PECAM-1 antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

CD31/PECAM‑1 in Mouse Embryo. CD31/PECAM-1 was detected in immersion fixed frozen sections of mouse embryo (14 d.p.c.) using Goat Anti-Human/Mouse/Rat CD31/PECAM-1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 10 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to developing guts. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Immunohistochemistry View Larger

CD31/PECAM‑1 in Rat Heart. CD31/PECAM‑1 was detected in immersion fixed paraffin-embedded sections of rat heart using Goat Anti-Human/Mouse/Rat CD31/PECAM‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to endothelial cells in vasculature.

Immunohistochemistry View Larger

Detection of CD31/PECAM‑1 in Human Placenta. CD31/PECAM‑1 was detected in immersion fixed paraffin-embedded sections of Human Placenta using Goat Anti-Human/Mouse/Rat CD31/PECAM‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628) at 15 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to endothelial cells in chorionic villi. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

Flow Cytometry View Larger

Detection of CD31/PECAM‑1 in HUVEC cells by Flow Cytometry. HUVEC cells were stained with Goat Anti-Human/Mouse/Rat CD31/PECAM‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628, filled histogram) or isotype control antibody (Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). View our protocol for Staining Membrane-associated Proteins.

Western Blot View Larger

Detection of Human CD31/PECAM‑1 by Western Blot. Western blot shows lysates of U937 human histiocytic lymphoma cell line. PVDF membrane was probed with 0.5 µg/ml of Goat Anti-Human/Mouse/Rat CD31/PECAM‑1 Antigen Affinity-purified Polyclonal Antibody (AF3628) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for CD31/PECAM‑1 at approximately 130 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1.

Immunohistochemistry Detection of Mouse CD31/PECAM-1 by Immunohistochemistry View Larger

Detection of Mouse CD31/PECAM-1 by Immunohistochemistry Representative image of immunostaining corresponding to the glucose transporter protein SLC2A1 (GLUT1) in 30 week-old Ins2AKITA and WT cerebral cortex. Mural cells (ANPEP, green), glucose transporter 1 (GLUT1, red), endothelium (PECAM1, cyan). n = 2, scale bar 50 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/30498224), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Human CD31/PECAM-1 by Western Blot View Larger

Detection of Human CD31/PECAM-1 by Western Blot AcSDKP suppresses TGF beta /smad signaling and EndMT through the FGFR1/FRS2 pathway. (a) HMVECs were treated with N-FGFR1 for 48 h, and the FGFR1, TGF beta R1 and TGF beta R2 protein levels were analyzed by western blot. (b) HMVECs were treated with TGF beta 2 in the presence or absence of N-FGFR1 for 15 min with or without AcSDKP preincubation. The p-smad3 and TGF beta R1 protein levels were analyzed by western blot. Densitometric analysis of the p-smad3/smad3 and TGF beta R1/ beta -actin levels (n=3) in each group was performed. (c) HMVECs were incubated with either N-FGFR1 in the presence or absence of TGF beta 2 for 48 h with or without preincubation with AcSDKP for 2 h or with N-FGFR1 in the presence or absence of TGF beta 2 for 48 h with or without 24 h of incubation with FGF2 (50 ng/ml). The CD31, SM22 alpha, FSP1 and alpha -SMA protein levels were analyzed by western blot. (d) HMVECs were transfected with FRS2 siRNA (100 nM) for 48 h with or without AcSDKP preincubation. The VE-cadherin, FSP1, vimentin, SM22 alpha and p-smad3 levels were analyzed by western blot. (e) HMVECs were treated with N-FGFR1 for 48 h or 15 min in the presence or absence of N-TGF beta (1, 2, 3) (1.0  μg/ml). The CD31, VE-cadherin, SM22 alpha, FSP1, TGF beta R1, TGF beta R2 and p-smad3 levels were analyzed by western blot Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28771231), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence AcSDKP inhibits TGF beta /smad signaling and EndMT and restores the FGFR1 and P-MAP4K4 levels in diabetic hearts. (a) Immunofluorescence microscopy analysis of CD31/FGFR1 and CD31/P-MAP4K4 in the heart tissues from each group of mice. The scale bar is 60 μm in each panel. The CD31 and FGFR1 double-labeled cells and the CD31 and P-MAP4K4 double-labeled cells in each visual field were assessed by fluorescence microscopy and quantified. For each section, images from six different fields of view at × 400 magnification were evaluated. (b and c) Immunofluorescence microscopy analysis of CD31/ alpha -SMA, VE-cadherin /SM22 alpha and CD31/p-smad3 expression levels in the heart tissues from each group of mice. The scale bar is 60 μm in each panel. The CD31 and alpha -SMA double-labeled cells, the VE-cadherin and SM22 alpha double-labeled cells and the CD31 and p-smad3 double-labeled cells in each visual field were analyzed by fluorescence microscopy and quantified. For each section, images from six different fields of view at × 400 magnification were evaluated. Four mice from each group were analyzed. (d) Western blot analysis of the FGFR1, P-MAP4K4, TGF beta 1, TGF beta 2 and TGF beta 3 levels in cardiac tissues. A representative blot from four independent experiments was shown. The densitometric analysis of western blot data was presented (n=4). The diabetic mice are abbreviated as DM in the figure Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28771231), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Human CD31/PECAM-1 by Western Blot View Larger

Detection of Human CD31/PECAM-1 by Western Blot AcSDKP suppresses TGF beta /smad signaling and EndMT through the FGFR1/FRS2 pathway. (a) HMVECs were treated with N-FGFR1 for 48 h, and the FGFR1, TGF beta R1 and TGF beta R2 protein levels were analyzed by western blot. (b) HMVECs were treated with TGF beta 2 in the presence or absence of N-FGFR1 for 15 min with or without AcSDKP preincubation. The p-smad3 and TGF beta R1 protein levels were analyzed by western blot. Densitometric analysis of the p-smad3/smad3 and TGF beta R1/ beta -actin levels (n=3) in each group was performed. (c) HMVECs were incubated with either N-FGFR1 in the presence or absence of TGF beta 2 for 48 h with or without preincubation with AcSDKP for 2 h or with N-FGFR1 in the presence or absence of TGF beta 2 for 48 h with or without 24 h of incubation with FGF2 (50 ng/ml). The CD31, SM22 alpha, FSP1 and alpha -SMA protein levels were analyzed by western blot. (d) HMVECs were transfected with FRS2 siRNA (100 nM) for 48 h with or without AcSDKP preincubation. The VE-cadherin, FSP1, vimentin, SM22 alpha and p-smad3 levels were analyzed by western blot. (e) HMVECs were treated with N-FGFR1 for 48 h or 15 min in the presence or absence of N-TGF beta (1, 2, 3) (1.0  μg/ml). The CD31, VE-cadherin, SM22 alpha, FSP1, TGF beta R1, TGF beta R2 and p-smad3 levels were analyzed by western blot Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28771231), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence AcSDKP inhibits TGF beta /smad signaling and EndMT and restores the FGFR1 and P-MAP4K4 levels in diabetic hearts. (a) Immunofluorescence microscopy analysis of CD31/FGFR1 and CD31/P-MAP4K4 in the heart tissues from each group of mice. The scale bar is 60 μm in each panel. The CD31 and FGFR1 double-labeled cells and the CD31 and P-MAP4K4 double-labeled cells in each visual field were assessed by fluorescence microscopy and quantified. For each section, images from six different fields of view at × 400 magnification were evaluated. (b and c) Immunofluorescence microscopy analysis of CD31/ alpha -SMA, VE-cadherin /SM22 alpha and CD31/p-smad3 expression levels in the heart tissues from each group of mice. The scale bar is 60 μm in each panel. The CD31 and alpha -SMA double-labeled cells, the VE-cadherin and SM22 alpha double-labeled cells and the CD31 and p-smad3 double-labeled cells in each visual field were analyzed by fluorescence microscopy and quantified. For each section, images from six different fields of view at × 400 magnification were evaluated. Four mice from each group were analyzed. (d) Western blot analysis of the FGFR1, P-MAP4K4, TGF beta 1, TGF beta 2 and TGF beta 3 levels in cardiac tissues. A representative blot from four independent experiments was shown. The densitometric analysis of western blot data was presented (n=4). The diabetic mice are abbreviated as DM in the figure Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28771231), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence Diminished permeability of liver sinusoids in Plvap-deficient mice.Neither by immunohistochemistry with antibodies against CD31 (A) nor by light microscopy of 1 µm semi-thin sections (B, Richardson's stain) obvious differences are detected with regards to the overall orientation and the density of liver sinusoids between 3-week-old Plvap-/- mice and wild-type littermates. Sinusoids of Plvap-deficient mice show a higher number of macrophages in their lumen (white arrows) and focal areas with accumulations of mononuclear cells in Disse's space (black arrows). Lower panels in B show higher magnifications. C, After perfusion of a wild-type animal with FITC-dextran, a strong FITC-signal (green) throughout the liver is detected. Immunolabeling with CD31 (red) suggests that FITC-dextran molecules have accumulated in the space of Disse. In contrast, in the Plvap-deficient littermate, the signal for FITC-dextran is much weaker and barely detectable. Nuclear DNA is labeled with DAPI (blue). Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0115005), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse CD31/PECAM-1 by Immunohistochemistry View Larger

Detection of Mouse CD31/PECAM-1 by Immunohistochemistry Blood-brain barrier permeability measurements in male Ins2AKITA and WT littermate controls. (a) Representative stereomicroscope fluorescence images of brains showing 1 kDa Alexa Fluor 555 cadaverine permeability in Ins2AKITA and WT after 2 h of dye circulation (n = 2). (b) Representative confocal images of coronal sections of 1 kDa Alexa Fluor 555 cadaverine injected mouse brains. ANPEP positive mural cells, green; PECAM1 positive vasculature, white. No Alexa Fluor 555 cadaverine leakage into brain parenchyma was observed either in Ins2AKITA or WT mice (n = 2, scale bar 30 μm). (c) Quantification of 1 kDa Alexa Fluor 555 cadaverine permeability in 26.5–32 week-old Ins2AKITA and WT mice after 2 h circulation (n = > 8, 3 independent experiments). y-axis shows the fold change in relative fluorescence units (RFU) per gram of brain tissue in relation to WT. (d) Quantification of 1 kDa Alexa Fluor 488 cadaverine permeability in 38 week-old Ins2AKITA and WT mice after 2 h circulation (n = 3). y-axis shows the fold change in relative fluorescence units (RFU) per gram of brain tissue in relation to WT. (e) Evans Blue dye permeability in 30 week-old Ins2AKITA and WT littermate control mice after overnight circulation (n = > 2). y-axis shows optical density (OD) at 620 nm per gram of tissue. PdgfbRet/Ret served as positive control for tracer leakage into the brain parenchyma. n.s., not significant, student’s t test. Data is presented as mean ± SEM. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/30498224), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence Diminished permeability of liver sinusoids in Plvap-deficient mice.Neither by immunohistochemistry with antibodies against CD31 (A) nor by light microscopy of 1 µm semi-thin sections (B, Richardson's stain) obvious differences are detected with regards to the overall orientation and the density of liver sinusoids between 3-week-old Plvap-/- mice and wild-type littermates. Sinusoids of Plvap-deficient mice show a higher number of macrophages in their lumen (white arrows) and focal areas with accumulations of mononuclear cells in Disse's space (black arrows). Lower panels in B show higher magnifications. C, After perfusion of a wild-type animal with FITC-dextran, a strong FITC-signal (green) throughout the liver is detected. Immunolabeling with CD31 (red) suggests that FITC-dextran molecules have accumulated in the space of Disse. In contrast, in the Plvap-deficient littermate, the signal for FITC-dextran is much weaker and barely detectable. Nuclear DNA is labeled with DAPI (blue). Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0115005), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence AcSDKP inhibits TGF beta /smad signaling and EndMT and restores the FGFR1 and P-MAP4K4 levels in diabetic hearts. (a) Immunofluorescence microscopy analysis of CD31/FGFR1 and CD31/P-MAP4K4 in the heart tissues from each group of mice. The scale bar is 60 μm in each panel. The CD31 and FGFR1 double-labeled cells and the CD31 and P-MAP4K4 double-labeled cells in each visual field were assessed by fluorescence microscopy and quantified. For each section, images from six different fields of view at × 400 magnification were evaluated. (b and c) Immunofluorescence microscopy analysis of CD31/ alpha -SMA, VE-cadherin /SM22 alpha and CD31/p-smad3 expression levels in the heart tissues from each group of mice. The scale bar is 60 μm in each panel. The CD31 and alpha -SMA double-labeled cells, the VE-cadherin and SM22 alpha double-labeled cells and the CD31 and p-smad3 double-labeled cells in each visual field were analyzed by fluorescence microscopy and quantified. For each section, images from six different fields of view at × 400 magnification were evaluated. Four mice from each group were analyzed. (d) Western blot analysis of the FGFR1, P-MAP4K4, TGF beta 1, TGF beta 2 and TGF beta 3 levels in cardiac tissues. A representative blot from four independent experiments was shown. The densitometric analysis of western blot data was presented (n=4). The diabetic mice are abbreviated as DM in the figure Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/28771231), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence CL and low temperature lead to WAT browning, angiogenesis, and an increased number of myofibroblast-like cells. a, b Histological analysis of adipocyte morphology (H&E), adipocytes (PERI), mitochondria (COX4), uncoupling protein 1 (UCP1), blood vessels (CD31), and myofibroblast-like cells ( alpha SMA) in a 5-day CL-316243-treated scWAT and visWAT compared to vehicle-treated control. b Two-week 4 °C-treated scWAT and visWAT compared to 30 °C control. Double-headed arrows mark adipocyte diameter. Arrows point to respective positive signals. c–l Quantifications of adipocyte size and positive signals per field of COX4, UCP1, CD31, and alpha SMA of CL-316243- and vehicle-, and 30 °C- and 4 °C- treated scWATs and visWATs (>30 adipocytes per field; n = 10 random fields; n = 5 mice per group). PERI, perilipin; COX4, mitochondrial complex 4; UCP1, uncoupling protein 1. Scale bars, 100 μm. NS, not significant. *P < 0.05, **P < 0.01, and ***P < 0.001 by Student’s t-test. Data presented as mean ± s.e.m. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41467-017-02158-z), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunocytochemistry/ Immunofluorescence Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence View Larger

Detection of Mouse CD31/PECAM-1 by Immunocytochemistry/Immunofluorescence CL and low temperature lead to WAT browning, angiogenesis, and an increased number of myofibroblast-like cells. a, b Histological analysis of adipocyte morphology (H&E), adipocytes (PERI), mitochondria (COX4), uncoupling protein 1 (UCP1), blood vessels (CD31), and myofibroblast-like cells ( alpha SMA) in a 5-day CL-316243-treated scWAT and visWAT compared to vehicle-treated control. b Two-week 4 °C-treated scWAT and visWAT compared to 30 °C control. Double-headed arrows mark adipocyte diameter. Arrows point to respective positive signals. c–l Quantifications of adipocyte size and positive signals per field of COX4, UCP1, CD31, and alpha SMA of CL-316243- and vehicle-, and 30 °C- and 4 °C- treated scWATs and visWATs (>30 adipocytes per field; n = 10 random fields; n = 5 mice per group). PERI, perilipin; COX4, mitochondrial complex 4; UCP1, uncoupling protein 1. Scale bars, 100 μm. NS, not significant. *P < 0.05, **P < 0.01, and ***P < 0.001 by Student’s t-test. Data presented as mean ± s.e.m. Image collected and cropped by CiteAb from the following publication (https://www.nature.com/articles/s41467-017-02158-z), licensed under a CC-BY license. Not internally tested by R&D Systems.

Flow Cytometry View Larger

Detection of CD31/PECAM‑1 in Whole Blood Granulocytes by Flow Cytometry Whole blood granulocytes were stained with Goat Anti-Human/Mouse/Rat CD31/PECAM‑1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3628, filled histogram) or isotype control antibody (Catalog # AB-108-C, open histogram) followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107). View our protocol for Staining Membrane-associated Proteins.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Neutrophil depletion reduces BBB breakdown and increases neovascularization after stroke. f, g Representative confocal images (f) and quantitative analysis of IgG extravascular deposits (g) in the peri-infarct cortex at 14 days in sham-operated mice and mice treated with control antibody or anti-Ly6G antibody (n = 6). One-way ANOVA test was applied with *P < 0.0001 (Sham vs. Isotype), *P = 0.0041 (Isotype vs. Anti-Ly6G). Bar = 15 μm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32427863), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Increased vascular remodeling by delayed inhibition of NET formation.a–d Representative confocal images (a, c) and quantitative analysis of IgG extravascular deposits (b, d) in the peri-infarct cortex at 14 days. Mice were subjected to stroke and treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle starting at 7 days (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.0392 (b), *P = 0.0384 (d). Bar = 10 μm. e–l Representative confocal images (e, g) of CD31-positive microvessels and in-vivo multiphoton microscopy images of perfused cortical capillaries with intravenously injected FITC-dextran (i, k) in the peri-infarct cortex at 14 days in mice treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle. Bar = 40 μm (e, g) and 100 µm (i, k). Quantification of microvascular density (f, h) and perfused capillary length (j, l) for each group (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.00378 (f), *P = 0.0364 (h), *P = 0.0026 (j), *P = 0.0006 (l). Data are presented as mean ± SD. Source data underlying graph b, d, f, h, j, and l are provided as a Source Data file. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32427863), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Increased vascular remodeling by delayed inhibition of NET formation.a–d Representative confocal images (a, c) and quantitative analysis of IgG extravascular deposits (b, d) in the peri-infarct cortex at 14 days. Mice were subjected to stroke and treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle starting at 7 days (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.0392 (b), *P = 0.0384 (d). Bar = 10 μm. e–l Representative confocal images (e, g) of CD31-positive microvessels and in-vivo multiphoton microscopy images of perfused cortical capillaries with intravenously injected FITC-dextran (i, k) in the peri-infarct cortex at 14 days in mice treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle. Bar = 40 μm (e, g) and 100 µm (i, k). Quantification of microvascular density (f, h) and perfused capillary length (j, l) for each group (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.00378 (f), *P = 0.0364 (h), *P = 0.0026 (j), *P = 0.0006 (l). Data are presented as mean ± SD. Source data underlying graph b, d, f, h, j, and l are provided as a Source Data file. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32427863), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Neutrophil depletion reduces BBB breakdown and increases neovascularization after stroke. h, j Representative confocal images (h) of CD31-positive microvessels and in-vivo multiphoton microscopy images of perfused cortical capillaries with intravenously injected FITC-dextran (MW = 2000,000 Da) (j) in the peri-infarct cortex at 14 days in mice treated with control antibody or anti-Ly6G antibody, compared with sham-operated mice. Bar = 50 μm (e) and 100 µm (g) Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32427863), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Increased vascular remodeling by delayed inhibition of NET formation.a–d Representative confocal images (a, c) and quantitative analysis of IgG extravascular deposits (b, d) in the peri-infarct cortex at 14 days. Mice were subjected to stroke and treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle starting at 7 days (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.0392 (b), *P = 0.0384 (d). Bar = 10 μm. e–l Representative confocal images (e, g) of CD31-positive microvessels and in-vivo multiphoton microscopy images of perfused cortical capillaries with intravenously injected FITC-dextran (i, k) in the peri-infarct cortex at 14 days in mice treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle. Bar = 40 μm (e, g) and 100 µm (i, k). Quantification of microvascular density (f, h) and perfused capillary length (j, l) for each group (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.00378 (f), *P = 0.0364 (h), *P = 0.0026 (j), *P = 0.0006 (l). Data are presented as mean ± SD. Source data underlying graph b, d, f, h, j, and l are provided as a Source Data file. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32427863), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Neutrophils accumulate in the brain during all stages of ischemic stroke. f Representative confocal images of Ly6G-labeled neutrophils (green) and CD31-positive microvessels (white) in the peri-infarct cortex of mice at 3 days. Nuclei were visualized with Hoechst. Neutrophils were observed within brain vessels and migrated into the parenchyma. Bar = 40 μm. Independent experiments are repeated at least three times. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32427863), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Diminished permeability of liver sinusoids in Plvap-deficient mice.Neither by immunohistochemistry with antibodies against CD31 (A) nor by light microscopy of 1 µm semi-thin sections (B, Richardson's stain) obvious differences are detected with regards to the overall orientation and the density of liver sinusoids between 3-week-old Plvap-/- mice and wild-type littermates. Sinusoids of Plvap-deficient mice show a higher number of macrophages in their lumen (white arrows) and focal areas with accumulations of mononuclear cells in Disse's space (black arrows). Lower panels in B show higher magnifications. C, After perfusion of a wild-type animal with FITC-dextran, a strong FITC-signal (green) throughout the liver is detected. Immunolabeling with CD31 (red) suggests that FITC-dextran molecules have accumulated in the space of Disse. In contrast, in the Plvap-deficient littermate, the signal for FITC-dextran is much weaker and barely detectable. Nuclear DNA is labeled with DAPI (blue). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/25541982), licensed under a CC-BY license. Not internally tested by R&D Systems.

Immunohistochemistry Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry View Larger

Detection of Mouse Human/Mouse/Rat CD31/PECAM-1 Antibody by Immunohistochemistry Increased vascular remodeling by delayed inhibition of NET formation.a–d Representative confocal images (a, c) and quantitative analysis of IgG extravascular deposits (b, d) in the peri-infarct cortex at 14 days. Mice were subjected to stroke and treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle starting at 7 days (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.0392 (b), *P = 0.0384 (d). Bar = 10 μm. e–l Representative confocal images (e, g) of CD31-positive microvessels and in-vivo multiphoton microscopy images of perfused cortical capillaries with intravenously injected FITC-dextran (i, k) in the peri-infarct cortex at 14 days in mice treated with either anti-Ly6G antibody, control antibody, DNase 1, or vehicle. Bar = 40 μm (e, g) and 100 µm (i, k). Quantification of microvascular density (f, h) and perfused capillary length (j, l) for each group (n = 6), unpaired two-tailed Student’s t-test was applied with *P = 0.00378 (f), *P = 0.0364 (h), *P = 0.0026 (j), *P = 0.0006 (l). Data are presented as mean ± SD. Source data underlying graph b, d, f, h, j, and l are provided as a Source Data file. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/32427863), licensed under a CC-BY license. Not internally tested by R&D Systems.

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Background: CD31/PECAM-1

PECAM-1 (Platelet-Endothelial Cell Adhesion Molecule-1), also known as CD31, is a 130 kDa type I transmembrane glycoprotein adhesion molecule in the immunoglobulin superfamily (1, 2). Expression is restricted to cells involved in circulation, especially endothelial cells, platelets, monocytes, neutrophils and lymphocyte subsets. PECAM-1 is concentrated at cell-cell junctions and is required for Transendothelial Migration (TEM) (1-3). The Extracellular Domain (ECD) of PECAM-1 has ten potential N-linked glycosylation sites and six C2-type Ig-like domains, the first of which is critical for adhesion and extravasation (3, 4). The cytoplasmic domain contains Immunoregulatory Tyrosine-based Inhibitory and Switch Motifs (ITIM, ITSM) that mediate both inhibition and activation via phosphotyrosine-mediated engagement of SH2-containing signaling molecules (1, 5). Metalloproteinase-mediated ectodomain shedding occurs during apoptosis (6) but increased serum PECAM-1 ectodomain in HIV and active multiple sclerosis occurs independent of apoptosis (7, 8). In humans, expression of six isoforms with exon deletions in the cytoplasmic domain is tissue- and stage-specific, but full-length PECAM-1 is predominant. A form lacking the ITSM predominates in mouse (9). Mouse PECAM-1 ECD shows 77%, 63%, 63%, 63%, and 61% amino acid (aa) identity with rat, human, canine, porcine, and bovine PECAM-1, respectively. PECAM-1 participates with other adhesion molecules in some functions, but is the critical molecule for TEM. Homotypic PECAM-1 adhesion in trans, combined with cycling of PECAM-1 to and from surface-connected endothelial cell vesicles, leads leukocytes across endothelial tight junctions (3, 10). Homotypic adhesion and signaling functions also strongly suppress mitochondria-dependent apoptosis (11). In platelets, PECAM-1 is necessary for limiting thrombus formation (12) and promoting integrin-mediated clot retraction and platelet spreading (13), but mechanisms for these phenomena are unclear. PECAM-/- mice are deficient in chemokine-mediated chemotaxis (14).

References
  1. Ilan, N. and J.A. Madri (2003) Curr. Opin. Cell Biol. 15:515.
  2. Xie, Y. and W.A. Muller (1993) Proc. Natl. Acad. Sci. USA 90:5569.
  3. Liao, F. et al. (1997) J. Exp. Med. 185:1349.
  4. Nakada, M.T. et al. (2000) J. Immunol. 164:452.
  5. Chemnitz, J.M. et al. (2004) J. Immunol. 173:945.
  6. Ilan, N. et al. (2001) FASEB J. 15:362.
  7. Eugenin, E.A. et al. (2006) J. Leukoc. Biol. 79:444.
  8. Losy, J. et al. (1999) J. Neuroimmunol. 99:169.
  9. Wang, Y. et al. (2003) Am. J. Physiol. Heart Circ. Physiol. 284:H1008.
  10. Mamdouh, Z. et al. (2003) Nature 421:748.
  11. Gao, C. et al. (2003) Blood 102:169.
  12. Falati, S. et al. (2006) Blood 107:535.
  13. Wee, J.L. and D.E. Jackson (2005) Blood 106:3816.
  14. Wu, Y. et al. (2005) J. Immunol. 175:3484.
Long Name
Platelet Endothelial Cell Adhesion Molecule 1
Entrez Gene IDs
5175 (Human); 18613 (Mouse); 29583 (Rat)
Alternate Names
adhesion molecule; CD31 antigen; CD31; CD31/EndoCAM; EndoCAM; FLJ34100; FLJ58394; GPIIA'; PECA1; PECAM1; PECAM-1; PECAM-1, CD31/EndoCAM; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule

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Citations for Human/Mouse/Rat CD31/PECAM-1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

503 Citations: Showing 1 - 10
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  1. Engrailed 1 coordinates cytoskeletal reorganization to induce myofibroblast differentiation
    Authors: Gyorfi Ah, Matei Ae, Fuchs M Et Al.
    The Journal of experimental medicine
  2. TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells.
    Authors: Padilla J, Carpenter A, Das ND et al.
    Am. J. Physiol. Heart Circ. Physiol.
  3. Semiautomated pipeline for quantitative analysis of heart histopathology
    Authors: Droste, P;Wong, DWL;Hohl, M;von Stillfried, S;Klinkhammer, BM;Boor, P;
    Journal of translational medicine
  4. Mono- and multi-nucleated ventricular cardiomyocytes constitute a transcriptionally homogenous cell population
    Authors: Yekelchyk M, Guenther S, Preussner J, Braun T
    Basic Res. Cardiol.
  5. CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation
    Authors: Andreata, F;Clément, M;Benson, RA;Hadchouel, J;Procopio, E;Even, G;Vorbe, J;Benadda, S;Ollivier, V;Ho-Tin-Noe, B;Le Borgne, M;Maffia, P;Nicoletti, A;Caligiuri, G;
    eLife
  6. FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway.
    Authors: Li J, Shi S, et al.
    Cell Death Dis
  7. Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic
    Authors: Logan T, Simon MJ, Rana A Et al.
    Cell
  8. Endothelial AHR activity prevents lung barrier disruption in viral infection
    Authors: Major, J;Crotta, S;Finsterbusch, K;Chakravarty, P;Shah, K;Frederico, B;D'Antuono, R;Green, M;Meader, L;Suarez-Bonnet, A;Priestnall, S;Stockinger, B;Wack, A;
    Nature
  9. THBS4/integrin alpha 2 axis mediates BM-MSCs to promote angiogenesis in gastric cancer associated with chronic Helicobacter pylori infection
    Authors: LingNan He, WeiJun Wang, HuiYing Shi, Chen Jiang, HaiLing Yao, YuRui Zhang et al.
    Aging (Albany NY)
  10. Exosomes released from educated mesenchymal stem cells accelerate cutaneous wound healing via promoting angiogenesis
    Authors: Xinyu Qiu, Jin Liu, Chenxi Zheng, Yuting Su, Lili Bao, Bin Zhu et al.
    Cell Proliferation
  11. Intravenously-injected gold nanoparticles (AuNPs) access intracerebral F98 rat gliomas better than AuNPs infused directly into the tumor site by convection enhanced delivery
    Authors: Henry M Smilowitz, Alexandria Meyers, Khalil Rahman, Nathaniel A Dyment, Dan Sasso, Crystal Xue et al.
    International Journal of Nanomedicine
  12. Host genetic modifiers of nonproductive angiogenesis inhibit breast cancer
    Authors: MJ Flister, SW Tsaih, A Stoddard, C Plasterer, J Jagtap, AK Parchur, G Sharma, AR Prisco, A Lemke, D Murphy, M Al-Gizawiy, M Straza, S Ran, AM Geurts, MR Dwinell, AS Greene, C Bergom, PS LaViolette, A Joshi
    Breast Cancer Res. Treat., 2017-05-31;0(0):.
  13. Facilitation of Reparative Dentin Using a Drug Repositioning Approach With 4-Phenylbutric Acid
    Authors: Lee E, Aryal Y, Kim T et al.
    Front Physiol
  14. A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver
    Authors: Inverso D, Shi J, Lee KH et al.
    Developmental cell
  15. Design and biofabrication of dermal regeneration scaffolds: role of oligomeric collagen fibril density and architecture
    Authors: David O Sohutskay, Kevin P Buno, Sunil S Tholpady, Samantha J Nier, Sherry L Voytik-Harbin
    Regenerative Medicine
  16. Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis
    Authors: A Heinrich, SJ Potter, L Guo, N Ratner, T DeFalco
    Cell Rep, 2020-04-14;31(2):107513.
  17. Aging of mouse intervertebral disc and association with back pain
    Authors: Vincent K, Mohanty S, Pinelli R et al.
    Bone
  18. Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization
    Authors: Yanagida K, Engelbrecht E, Niaudet C et al.
    Dev. Cell
  19. Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes
    Authors: Rutkowski, N;Görlitz, F;Wiesner, E;Binz-Lotter, J;Feil, S;Feil, R;Benzing, T;Hackl, MJ;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  20. IL-33/ST2 signaling in monocyte-derived macrophages maintains blood-brain barrier integrity and restricts infarctions early after ischemic stroke
    Authors: Wang, M;Dufort, C;Du, Z;Shi, R;Xu, F;Huang, Z;Sigler, AR;Leak, RK;Hu, X;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  21. Spatiotemporal lineage tracing reveals the dynamic spatial architecture of tumor growth and metastasis
    Authors: Jones, MG;Sun, D;Min, KHJ;Colgan, WN;Tian, L;Weir, JA;Chen, VZ;Koblan, LW;Yost, KE;Mathey-Andrews, N;Russell, AJC;Stickels, RR;Balderrama, KS;Rideout, WM;Chang, HY;Jacks, T;Chen, F;Weissman, JS;Yosef, N;Yang, D;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  22. ANXA1 Enhances the Proangiogenic Potential of Human Dental Pulp Stem Cells
    Authors: Ma, X;Zhao, B;Wang, C;Sun, M;Dai, Y;E, L;Gao, M;Liu, X;Jia, Y;Yue, W;Liu, H;
    Stem cells international
    Species: Human
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  23. Autologous micrografting improves regeneration of tissue-engineered urinary conduits in vivo
    Authors: Juul, N;Amoushahi, M;Willacy, O;Ji, M;Villa, C;Ajalloueian, F;Chamorro, C;Fossum, M;
    Scientific reports
    Species: Porcine
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  24. GCN2 kinase activation mediates pulmonary vascular remodeling and pulmonary arterial hypertension
    Authors: Zhu, MM;Dai, J;Dai, Z;Peng, Y;Zhao, YY;
    JCI insight
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  25. Optimized Enrichment of Murine Blood-Brain Barrier Vessels with a Critical Focus on Network Hierarchy in Post-Collection Analysis
    Authors: Abdelazim, H;Barnes, A;Stupin, J;Hasson, R;Muñoz-Ballester, C;Young, KL;Robel, S;Smyth, JW;Lamouille, S;Chappell, JC;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  26. Inhibiting Ca2+ channels in Alzheimer's disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia
    Authors: Korte, N;Barkaway, A;Wells, J;Freitas, F;Sethi, H;Andrews, SP;Skidmore, J;Stevens, B;Attwell, D;
    Nature neuroscience
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  27. Translocator protein 18?kDa (TSPO) is upregulated in rat brain after peripheral nerve injury and downregulated by diroximel fumarate
    Authors: Cazuza, RA;Zagrai, SM;Grieco, AR;Avery, TD;Abell, AD;Wey, HY;Loggia, ML;Grace, PM;
    Brain, behavior, and immunity
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  28. Regulation of angiogenesis by signal sequence-derived peptides
    Authors: Ghim, M;Wei, L;Jung, JJ;The, E;Kukreja, G;Neishabouri, A;Ahmad, AA;Raza, MZ;Golbazi, A;Hedayatyanfard, K;Nie, L;Zhang, J;Sadeghi, MM;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  29. Development of betabodies: the next generation of phosphatidylserine targeting agents
    Authors: Phinney, NZ;Huang, X;Toombs, JE;Brekken, RA;
    The Journal of biological chemistry
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  30. Modulating amacrine cell-derived dopamine signaling promotes optic nerve regeneration and preserves visual function
    Authors: Zhang, Q;Xue, J;Tang, J;Wu, S;Liu, Z;Wu, C;Liu, C;Liu, Y;Lin, J;Han, J;Liu, L;Chen, Y;Yang, J;Li, Z;Zhao, L;Wei, Y;Li, Y;Zhuo, Y;
    Science advances
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  31. Iron Chelator Deferiprone Restores Iron Homeostasis and Inhibits Retinal Neovascularization in Experimental Neovascular Age-Related Macular Degeneration
    Authors: Xu, Y;Huang, S;Zhou, S;Wang, X;Wei, M;Chen, X;Zong, R;Lin, X;Li, S;Liu, Z;Chen, Q;
    Investigative ophthalmology & visual science
    Species: Mouse
    Sample Types:
    Applications: Immunohistochemistry-Frozen
  32. Increasing Endoglin Deletion in Endothelial Cells Exacerbates the Severity of Brain Arteriovenous Malformation in Mouse
    Authors: Shabani, Z;Do Prado, LB;Zhang, R;Zhu, W;Shaligram, SS;Yadav, A;Wang, C;Su, H;
    Biomedicines
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  33. KIT in oocytes: a key factor for oocyte survival and reproductive lifespan
    Authors: Luan, Y;So, W;Dong, R;Abazarikia, A;Kim, SY;
    EBioMedicine
    Species: Human
    Sample Types: Tissue Array
    Applications: IHC-Pr
  34. Single nuclei transcriptomics reveal the differentiation trajectories of periosteal skeletal/stem progenitor cells in bone regeneration
    Authors: Perrin, S;Ethel, M;Bretegnier, V;Goachet, C;Wotawa, CA;Luka, M;Coulpier, F;Masson, C;Ménager, M;Colnot, C;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  35. Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis
    Authors: Park, H;Song, J;Jeong, HW;Grönloh, MLB;Koh, BI;Bovay, E;Kim, KP;Klotz, L;Thistlethwaite, PA;van Buul, JD;Sorokin, L;Adams, RH;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  36. Radiation-Induced Endothelial Ferroptosis Accelerates Atherosclerosis via the DDHD2-Mediated Nrf2/GPX4 Pathway
    Authors: Su, X;Liang, F;Zeng, Y;Yang, ZR;Deng, YZ;Xu, YH;Cai, XW;
    Biomolecules
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  37. Activation of a GPCR, ORL1 receptor: A novel therapy to prevent heart failure progression
    Authors: Pathan, S;Pugazenthi, A;Dixon, BR;Wensel, TG;Rosengart, TK;Mathison, M;
    Research square
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  38. Auto/Paracrine C-Type Natriuretic Peptide/Cyclic GMP Signaling Prevents Endothelial Dysfunction
    Authors: Werner, F;Naruke, T;Sülzenbrück, L;Schäfer, S;Rösch, M;Völker, K;Krebes, L;Abe beta er, M;Möllmann, D;Baba, HA;Schweda, F;Zernecke, A;Kuhn, M;
    International journal of molecular sciences
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  39. Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice
    Authors: Shi, R;Ye, J;Liu, Z;Wang, C;Wu, S;Shen, H;Suo, Q;Li, W;He, X;Zhang, Z;Tang, Y;Yang, GY;Wang, Y;
    Neural regeneration research
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  40. Pilose antler extracts promotes hair growth in androgenetic alopecia mice by activating hair follicle stem cells via the AKT and Wnt pathways
    Authors: Wang, F;He, G;Liu, M;Sun, Y;Ma, S;Sun, Z;Wang, Y;
    Frontiers in pharmacology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  41. Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation in Muscle
    Authors: Mann, CG;MacArthur, MR;Zhang, J;Gong, S;AbuSalim, JE;Hunter, CJ;Lu, W;Agius, T;Longchamp, A;Allagnat, F;Rabinowitz, J;Mitchell, JR;De Bock, K;Mitchell, SJ;
    bioRxiv : the preprint server for biology
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  42. Lactate transported by MCT1 plays an active role in promoting mitochondrial biogenesis and enhancing TCA flux in skeletal muscle
    Authors: Zhang, L;Xin, C;Wang, S;Zhuo, S;Zhu, J;Li, Z;Liu, Y;Yang, L;Chen, Y;
    Science advances
    Species: Mouse
    Sample Types: Cell Lysates, Tissue Homogenates, Whole Tissue
    Applications: Immunohistochemistry, Western Blot
  43. Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury
    Authors: Zhang, Q;Jing, Y;Gong, Q;Cai, L;Wang, R;Yang, D;Wang, L;Qu, M;Chen, H;Tang, Y;Tian, H;Ding, J;Xu, Z;
    Neural regeneration research
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  44. Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor
    Authors: Guo, T;Pei, F;Zhang, M;Yamada, T;Feng, J;Jing, J;Ho, TV;Chai, Y;
    Cell stem cell
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  45. Brain endothelial GSDMD activation mediates inflammatory BBB breakdown
    Authors: Wei, C;Jiang, W;Wang, R;Zhong, H;He, H;Gao, X;Zhong, S;Yu, F;Guo, Q;Zhang, L;Schiffelers, LDJ;Zhou, B;Trepel, M;Schmidt, FI;Luo, M;Shao, F;
    Nature
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  46. Adjudin protects blood-brain barrier integrity and attenuates neuroinflammation following intracerebral hemorrhage in mice
    Authors: Su, Q;Su, C;Zhang, Y;Guo, Y;Liu, Y;Liu, Y;Yong, VW;Xue, M;
    International immunopharmacology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  47. Osteocyte mitochondria regulate angiogenesis of transcortical vessels
    Authors: Liao, P;Chen, L;Zhou, H;Mei, J;Chen, Z;Wang, B;Feng, JQ;Li, G;Tong, S;Zhou, J;Zhu, S;Qian, Y;Zong, Y;Zou, W;Li, H;Zhang, W;Yao, M;Ma, Y;Ding, P;Pang, Y;Gao, C;Mei, J;Zhang, S;Zhang, C;Liu, D;Zheng, M;Gao, J;
    Nature communications
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Immunohistochemistry, Immunocytochemistry
  48. Endothelial cells regulate alveolar morphogenesis by constructing basement membranes acting as a scaffold for myofibroblasts
    Authors: Watanabe-Takano, H;Kato, K;Oguri-Nakamura, E;Ishii, T;Kobayashi, K;Murata, T;Tsujikawa, K;Miyata, T;Kubota, Y;Hanada, Y;Nishiyama, K;Watabe, T;Fässler, R;Ishii, H;Mochizuki, N;Fukuhara, S;
    Nature communications
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  49. High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models
    Authors: Xue, L;Hamilton, AG;Zhao, G;Xiao, Z;El-Mayta, R;Han, X;Gong, N;Xiong, X;Xu, J;Figueroa-Espada, CG;Shepherd, SJ;Mukalel, AJ;Alameh, MG;Cui, J;Wang, K;Vaughan, AE;Weissman, D;Mitchell, MJ;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  50. Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brain
    Authors: Wang, M;Zhang, L;Novak, SW;Yu, J;Gallina, IS;Xu, LL;Lim, CK;Fernandes, S;Shokhirev, MN;Williams, AE;Saxena, MD;Coorapati, S;Parylak, SL;Quintero, C;Molina, E;Andrade, LR;Manor, U;Gage, FH;
    Nature biotechnology
    Species: Human, Xenograft
    Sample Types: Organoid, Whole Tissue
    Applications: Immunohistochemistry
  51. Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model
    Authors: Zhilan, T;Zengyu, Z;Pengpeng, J;Hualan, Y;Chao, L;Yan, X;Zimin, G;Shuangxing, H;Weiwei, L;
    Journal of advanced research
    Species: Rat
    Sample Types: Cell Lysates, Tissue Homogenates, Whole Cells, Whole Tissue
    Applications: ICC, Western Blot, IHC
  52. Protection against overfeeding-induced weight gain is preserved in obesity but does not require FGF21 or MC4R
    Authors: Lund, C;Ranea-Robles, P;Falk, S;Rausch, DM;Skovbjerg, G;Vibe-Petersen, VK;Krauth, N;Skytte, JL;Vana, V;Roostalu, U;Pers, TH;Lund, J;Clemmensen, C;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  53. A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
    Authors: Hai, L;Hoffmann, DC;Wagener, RJ;Azorin, DD;Hausmann, D;Xie, R;Huppertz, MC;Hiblot, J;Sievers, P;Heuer, S;Ito, J;Cebulla, G;Kourtesakis, A;Kaulen, LD;Ratliff, M;Mandelbaum, H;Jung, E;Jabali, A;Horschitz, S;Ernst, KJ;Reibold, D;Warnken, U;Venkataramani, V;Will, R;Suvà, ML;Herold-Mende, C;Sahm, F;Winkler, F;Schlesner, M;Wick, W;Kessler, T;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  54. A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
    Authors: Ferrell, M;Wang, Z;Anderson, JT;Li, XS;Witkowski, M;DiDonato, JA;Hilser, JR;Hartiala, JA;Haghikia, A;Cajka, T;Fiehn, O;Sangwan, N;Demuth, I;König, M;Steinhagen-Thiessen, E;Landmesser, U;Tang, WHW;Allayee, H;Hazen, SL;
    Nature medicine
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  55. Impaired neuronal activity as a potential factor contributing to the underdeveloped cerebrovasculature in a young Parkinson's disease mouse model
    Authors: Jeong, JY;Lee, HJ;Kim, N;Li, Y;Rah, JC;Oh, WJ;
    Scientific reports
    Species: Transgenic Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  56. Crucial role for Sodium Hydrogen Exchangers in SGLT2 inhibitor-induced arterial relaxations
    Authors: Forrester, EA;Benítez-Angeles, M;Redford, KE;Rosenbaum, T;Abbott, GW;Barrese, V;Dora, K;Albert, AP;Dannesboe, J;Salles-Crawley, I;Jepps, TA;Greenwood, IA;
    bioRxiv : the preprint server for biology
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  57. Successful reconstruction of the rat ureter by a syngeneic collagen tube with a cardiomyocyte sheet
    Authors: Yamamoto, S;Matsui, K;Kinoshita, Y;Hiroshi Sasaki, ;Sekine, H;Saito, Y;Nakayama, Y;Kume, H;Kimura, T;Yokoo, T;Kobayashi, E;
    Regenerative therapy
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  58. Mapping cardiac remodeling in chronic kidney disease
    Authors: Kaesler, N;Cheng, M;Nagai, J;O'Sullivan, J;Peisker, F;Bindels, EMJ;Babler, A;Moellmann, J;Droste, P;Franciosa, G;Dugourd, A;Saez-Rodriguez, J;Neuss, S;Lehrke, M;Boor, P;Goettsch, C;Olsen, JV;Speer, T;Lu, TS;Lim, K;Floege, J;Denby, L;Costa, I;Kramann, R;
    Science advances
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  59. Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke
    Authors: Wang, G;Li, Z;Lin, P;Zhang, H;Wang, Y;Zhang, T;Wang, H;Li, H;Lin, L;Zhao, Y;Jia, L;Chen, Y;Ji, H;Zhao, W;Fu, Z;Zhong, Z;
    International immunopharmacology
    Species: Mouse
    Sample Types: Whole Tissues
    Applications: IHC
  60. A novel small molecule, CU05-1189, targeting the pleckstrin homology domain of PDK1 suppresses VEGF-mediated angiogenesis and tumor growth by blocking the Akt signaling pathway
    Authors: Park, J;Zhang, H;Kwak, HJ;Gadhe, CG;Kim, Y;Kim, H;Noh, M;Shin, D;Ha, SJ;Kwon, YG;
    Frontiers in pharmacology
    Species: Mouse
    Sample Types: Matrigel Plug
    Applications: IHC
  61. Ultrasound-guided Photoacoustic image Annotation Toolkit in MATLAB (PHANTOM) for preclinical applications
    Authors: Sweeney, A;Arora, A;Edwards, S;Mallidi, S;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  62. Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer
    Authors: Yang Feng, Qingchen Yuan, Rachel C. Newsome, Troy Robinson, Robert L. Bowman, Ashley N. Zuniga et al.
    Journal of Experimental Medicine
  63. Catalpol rescues LPS-induced cognitive impairment via inhibition of NF-?b-regulated neuroinflammation and up-regulation of TrkB-mediated BDNF secretion in mice
    Authors: Hu, W;Zou, L;Yu, N;Wu, Z;Yang, W;Wu, T;Liu, Y;Pu, Y;Jiang, Y;Zhang, J;Zhu, H;Cheng, F;Feng, S;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  64. IL-1?+ macrophages fuel pathogenic inflammation in pancreatic cancer
    Authors: Caronni, N;La Terza, F;Vittoria, FM;Barbiera, G;Mezzanzanica, L;Cuzzola, V;Barresi, S;Pellegatta, M;Canevazzi, P;Dunsmore, G;Leonardi, C;Montaldo, E;Lusito, E;Dugnani, E;Citro, A;Ng, MSF;Schiavo Lena, M;Drago, D;Andolfo, A;Brugiapaglia, S;Scagliotti, A;Mortellaro, A;Corbo, V;Liu, Z;Mondino, A;Dellabona, P;Piemonti, L;Taveggia, C;Doglioni, C;Cappello, P;Novelli, F;Iannacone, M;Ng, LG;Ginhoux, F;Crippa, S;Falconi, M;Bonini, C;Naldini, L;Genua, M;Ostuni, R;
    Nature
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  65. Hydrogen sulfide donor activates AKT-eNOS signaling and promotes lymphatic vessel formation
    Authors: Aithabathula, RV;Pervaiz, N;Kathuria, I;Swanson, M;Singh, UP;Kumar, S;Park, F;Singla, B;
    PloS one
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  66. Structural and molecular basis of choline uptake into the brain by FLVCR2
    Authors: Cater, RJ;Mukherjee, D;Iturbe, EG;Erramilli, SK;Chen, T;Koo, K;Grez, NS;Reckers, A;Kloss, B;Gawda, T;Choy, BC;Zheng, Z;Clarke, OB;Yee, SW;Kossiakoff, AA;Quick, M;Arnold, T;Mancia, F;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  67. ICI 182,780 Attenuates Selective Upregulation of Uterine Artery Cystathionine ?-Synthase Expression in Rat Pregnancy
    Authors: Bai, J;Li, Y;Yan, G;Zhou, J;Salmeron, AG;Fategbe, OT;Kumar, S;Chen, X;Chen, DB;
    International journal of molecular sciences
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  68. Combination human umbilical cord perivascular and endothelial colony forming cell therapy for ischemic cardiac injury
    Authors: Iqbal F, Johnston A, Wyse B et al.
    npj Regenerative Medicine
  69. Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
    Authors: Tixi W, Maldonado M, Chang YT et al.
    eLife
  70. Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation
    Authors: Freitas-Andrade, M;Comin, CH;Van Dyken, P;Ouellette, J;Raman-Nair, J;Blakeley, N;Liu, QY;Leclerc, S;Pan, Y;Liu, Z;Carrier, M;Thakur, K;Savard, A;Rurak, GM;Tremblay, MÈ;Salmaso, N;da F Costa, L;Coppola, G;Lacoste, B;
    Nature communications
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  71. TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
    Authors: Wang, Y;Wu, T;Tsai, MC;Rezzonico, MG;Abdel-Haleem, AM;Xie, L;Gandham, VD;Ngu, H;Stark, K;Glock, C;Xu, D;Foreman, O;Friedman, BA;Sheng, M;Hanson, JE;
    eLife
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  72. Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms
    Authors: Elodie Grockowiak, Claudia Korn, Justyna Rak, Veronika Lysenko, Adrien Hallou, Francesca M. Panvini et al.
    Nature Cancer
  73. The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions
    Authors: Fan Z, Ardicoglu R, Batavia AA et al.
    Angiogenesis
  74. Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants
    Authors: de Melo GD, Perraud V, Alvarez F et al.
    Nature communications
  75. Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver
    Authors: Thapa K, Kadiri JJ, Saukkonen K et al.
    eLife
  76. Proteomics identifies lipocalin-2 in neonatal inflammation associated with cerebrovascular alteration in mice and preterm infants
    Authors: Giacomo Gravina, Maryam Ardalan, Tetyana Chumak, Anders K. Nilsson, Joakim C. Ek, Hanna Danielsson et al.
    iScience
  77. Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization
    Authors: Jahn, D;Knapstein, PR;Otto, E;Köhli, P;Sevecke, J;Graef, F;Graffmann, C;Fuchs, M;Jiang, S;Rickert, M;Erdmann, C;Appelt, J;Revend, L;Küttner, Q;Witte, J;Rahmani, A;Duda, G;Xie, W;Donat, A;Schinke, T;Ivanov, A;Tchouto, MN;Beule, D;Frosch, KH;Baranowsky, A;Tsitsilonis, S;Keller, J;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  78. Ropinirole Cotreatment Prevents Perivascular Glial Recruitment in a Rat Model of L-DOPA-Induced Dyskinesia
    Authors: Elabi, OF;Espa, E;Skovgård, K;Fanni, S;Cenci, MA;
    Cells
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  79. Traumatic brain injury stimulates sympathetic tone-mediated bone marrow myelopoiesis to favor fracture healing
    Authors: Weijian Liu, Wei Chen, Mao Xie, Chao Chen, Zengwu Shao, Yiran Zhang et al.
    Signal Transduction and Targeted Therapy
  80. Torpor-like Hypothermia Induced by A1 Adenosine Receptor Agonist: A Novel Approach to Protect against Neuroinflammation
    Authors: Fu, K;Hui, C;Wang, X;Ji, T;Li, X;Sun, R;Xing, C;Fan, X;Gao, Y;Su, L;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  81. Single‐Cell RNA Sequencing and Spatial Transcriptomics Reveal Pathogenesis of Meningeal Lymphatic Dysfunction after Experimental Subarachnoid Hemorrhage
    Authors: Xiaoyu Wang, Anke Zhang, Qian Yu, Zelin Wang, Junjie Wang, Penglei Xu et al.
    Advanced Science
  82. In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles
    Authors: Kewa Gao, Jie Li, Hengyue Song, Hesong Han, Yongheng Wang, Boyan Yin et al.
    Bioactive Materials
  83. Acute stress induces long-term metabolic, functional, and structural remodeling of the heart
    Authors: Yoganathan, T;Perez-Liva, M;Balvay, D;Le Gall, M;Lallemand, A;Certain, A;Autret, G;Mokrani, Y;Guillonneau, F;Bruce, J;Nguyen, V;Gencer, U;Schmitt, A;Lager, F;Guilbert, T;Bruneval, P;Vilar, J;Maissa, N;Mousseaux, E;Viel, T;Renault, G;Kachenoura, N;Tavitian, B;
    Nature communications
    Species: Rat
    Sample Types: Whole Tissues
    Applications: IHC
  84. Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-?-myoCAF-Dependent Mechanism
    Authors: Wu J, Jing X, Du Q et al.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany)
  85. Three-Dimensional Histological Characterization of the Placental Vasculature Using Light Sheet Microscopy
    Authors: Freise, L;Behncke, RY;Allerkamp, HH;Sandermann, TH;Chu, NH;Funk, EM;Hondrich, LJ;Riedel, A;Witzel, C;Hansmeier, NR;Danyel, M;Gellhaus, A;Dechend, R;Hägerling, R;
    Biomolecules
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  86. Fetal brain vulnerability to SARS-CoV-2 infection
    Authors: McMahon CL, Castro J, Silvas J et al.
    Brain, behavior, and immunity
  87. Krause corpuscles of the genitalia are vibrotactile sensors required for normal sexual behavior
    Authors: Qi, L;Iskols, M;Handler, A;Ginty, DD;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  88. HPV-positive murine oral squamous cell carcinoma: development and characterization of a new mouse tumor model for immunological studies
    Authors: Modic, Z;Cemazar, M;Markelc, B;Cör, A;Sersa, G;Kranjc Brezar, S;Jesenko, T;
    Journal of translational medicine
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  89. Endothelial progenitor cells derived from embryonic stem cells prevent alveolar simplification in a murine model of bronchopulmonary dysplasia
    Authors: Olena A. Kolesnichenko, Hannah M. Flood, Yufang Zhang, Vladimir Ustiyan, Hayde K. Cuervo Jimenez, Tanya V. Kalin et al.
    Frontiers in Cell and Developmental Biology
  90. Cognitive Impairments, Neuroinflammation and Blood–Brain Barrier Permeability in Mice Exposed to Chronic Sleep Fragmentation during the Daylight Period
    Authors: Clementine Puech, Mohammad Badran, Alexandra R. Runion, Max B. Barrow, Kylie Cataldo, David Gozal
    International Journal of Molecular Sciences
  91. Scalable projected Light Sheet Microscopy for high-resolution imaging of large samples
    Authors: Chen, Y;Gong, C;Chauhan, S;De La Cruz, ED;Datta, MS;Tomer, R;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  92. Tumour extracellular vesicles and particles induce liver metabolic dysfunction
    Authors: Wang, G;Li, J;Bojmar, L;Chen, H;Li, Z;Tobias, GC;Hu, M;Homan, EA;Lucotti, S;Zhao, F;Posada, V;Oxley, PR;Cioffi, M;Kim, HS;Wang, H;Lauritzen, P;Boudreau, N;Shi, Z;Burd, CE;Zippin, JH;Lo, JC;Pitt, GS;Hernandez, J;Zambirinis, CP;Hollingsworth, MA;Grandgenett, PM;Jain, M;Batra, SK;DiMaio, DJ;Grem, JL;Klute, KA;Trippett, TM;Egeblad, M;Paul, D;Bromberg, J;Kelsen, D;Rajasekhar, VK;Healey, JH;Matei, IR;Jarnagin, WR;Schwartz, RE;Zhang, H;Lyden, D;
    Nature
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  93. Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS viral infection
    Authors: Ayasoufi, K;Wolf, DM;Namen, SL;Jin, F;Tritz, ZP;Pfaller, CK;Zheng, J;Goddery, EN;Fain, CE;Gulbicki, LR;Borchers, AL;Reesman, RA;Yokanovich, LT;Maynes, MA;Bamkole, MA;Khadka, RH;Hansen, MJ;Wu, LJ;Johnson, AJ;
    Brain, behavior, and immunity
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  94. A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells
    Authors: Li, X;Jiang, Q;Song, G;Barkestani, MN;Wang, Q;Wang, S;Fan, M;Fang, C;Jiang, B;Johnson, J;Geirsson, A;Tellides, G;Pober, JS;Jane-Wit, D;
    Nature communications
    Species: Human, Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  95. Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space
    Authors: Chendke G, Kharbikar B, Ashe S et al.
    Bioengineering & Translational Medicine
  96. LPS-Induced Systemic Inflammation Affects the Dynamic Interactions of Astrocytes and Microglia with the Vasculature of the Mouse Brain Cortex
    Authors: Xingi, E;Koutsoudaki, PN;Thanou, I;Phan, MS;Margariti, M;Scheller, A;Tinevez, JY;Kirchhoff, F;Thomaidou, D;
    Cells
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  97. CCN2/CTGF tip the balance of growth factors towards TGF-beta 2 in primary open-angle glaucoma
    Authors: Andrea E. Dillinger, Sabrina Kuespert, Amin A. Seleem, Jakob Neuendorf, Magdalena Schneider, Rudolf Fuchshofer
    Frontiers in Molecular Biosciences
  98. Therapeutic activation of endothelial sphingosine‐1‐phosphate receptor 1 by chaperone‐bound S1P suppresses proliferative retinal neovascularization
    Authors: Colin Niaudet, Bongnam Jung, Andrew Kuo, Steven Swendeman, Edward Bull, Takahiro Seno et al.
    EMBO Molecular Medicine
  99. Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal
    Authors: Hao, X;Shen, Y;Chen, N;Zhang, W;Valverde, E;Wu, L;Chan, HL;Xu, Z;Yu, L;Gao, Y;Bado, I;Michie, LN;Rivas, CH;Dominguez, LB;Aguirre, S;Pingel, BC;Wu, YH;Liu, F;Ding, Y;Edwards, DG;Liu, J;Alexander, A;Ueno, NT;Hsueh, PR;Tu, CY;Liu, LC;Chen, SH;Hung, MC;Lim, B;Zhang, XH;
    Cell stem cell
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  100. Lesion-specific suppression of YAP/TAZ by biomimetic nanodrug ameliorates atherosclerosis development
    Authors: Huang, HC;Wang, TY;Rousseau, J;Mungaray, M;Michaud, C;Plaisier, C;Chen, ZB;Wang, KC;
    bioRxiv : the preprint server for biology
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  101. A Soluble Platelet-Derived Growth Factor Receptor-? Originates via Pre-mRNA Splicing in the Healthy Brain and Is Upregulated during Hypoxia and Aging
    Authors: Payne LB, Abdelazim H, Hoque M et al.
    Biomolecules
  102. Salmonella infection induces the reorganization of follicular dendritic cell networks concomitant with the failure to generate germinal centers
    Authors: Edith Marcial-Juárez, Marisol Pérez-Toledo, Saba Nayar, Elena Pipi, Areej Alshayea, Ruby Persaud et al.
    iScience
  103. RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
    Authors: Kayleah M. Meneses, Prita Pandya, Jennifer A. Lindemann, Dania S. Al-Qasrawi, Ryan A. Argo, Celeste M. Weems et al.
    Cancer Research Communications
  104. Inhibition of neutrophil extracellular trap formation attenuates NLRP1-dependent neuronal pyroptosis via STING/IRE1 alpha pathway after traumatic brain injury in mice
    Authors: Yiyao Cao, Mingming Shi, Liang Liu, Yan Zuo, Haoran Jia, Xiaobin Min et al.
    Frontiers in Immunology
  105. Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease
    Authors: M Vicente-Ro, R Mancuso, A Peris-Yagu, C Simmons, NIMA Conso, D Gómez-Nico, VH Perry, F Turkheimer, S Lovestone, CA Parker, D Cash
    Journal of Neuroinflammation, 2023-04-09;20(1):92.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  106. Exogenous interleukin 33 enhances the brain's lymphatic drainage and toxic protein clearance in acute traumatic brain injury mice
    Authors: M Liu, J Huang, T Liu, J Yuan, C Lv, Z Sha, C Wu, W Jiang, X Liu, M Nie, Y Chen, S Dong, Y Qian, C Gao, Y Fan, D Wu, R Jiang
    Acta neuropathologica communications, 2023-04-07;11(1):61.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  107. Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility
    Authors: Cinato M, Mardani I, Miljanovic A et al.
    Life Science Alliance
  108. Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer's disease
    Authors: BJ Choi, MH Park, KH Park, WH Han, HJ Yoon, HY Jung, JY Hong, MR Chowdhury, KY Kim, J Lee, IS Song, M Pang, MK Choi, E Gulbins, M Reichel, J Kornhuber, CW Hong, C Kim, SH Kim, EH Schuchman, HK Jin, JS Bae
    Nature Communications, 2023-03-24;14(1):1631.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  109. Three-dimensional visualization of neural networks inside bone by Osteo-DISCO protocol and alteration of bone remodeling by surgical nerve ablation
    Authors: K Utagawa, T Shin, H Yamada, H Ochi, S Sunamura, A Unno, C Akazawa, M Ema, S Takeda, A Okawa, S Sato
    Scientific Reports, 2023-03-22;13(1):4674.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  110. Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis
    Authors: Q Yu, I Gamayun, P Wartenberg, Q Zhang, S Qiao, S Kusumakshi, S Candlish, V Götz, S Wen, D Das, A Wyatt, V Wahl, F Ectors, K Kattler, D Yildiz, V Prevot, M Schwaninge, G Ternier, P Giacobini, P Ciofi, TD Müller, U Boehm
    Nature Communications, 2023-03-22;14(1):1588.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  111. Sertoli cells are the unique source of stem cell factor for spermatogenesis
    Authors: Yi Jacky Peng, Xinyu Thomas Tang, Hui Sophie Shu, Wenjie Dong, Hongfang Shao, Bo O. Zhou
    Development
  112. Trans-differentiation of trophoblast stem cells: implications in placental biology
    Authors: Madhurima Paul, Shreeta Chakraborty, Safirul Islam, Rupasri Ain
    Life Science Alliance
  113. Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing
    Authors: Hengyue Song, Kewa Gao, Dake Hao, Andrew Li, Ruiwu Liu, Bryan Anggito et al.
    Frontiers in Pharmacology
  114. 17 beta -Estradiol promotes sex-specific dysfunction in isolated human arterioles
    Authors: Gopika SenthilKumar, Boran Katunaric, Henry Bordas-Murphy, Micaela Young, Erin L. Doren, Mary E. Schulz et al.
    American Journal of Physiology-Heart and Circulatory Physiology
  115. Limiting Mrs2-dependent mitochondrial Mg2+ uptake induces metabolic programming in prolonged dietary stress
    Authors: TR Madaris, M Venkatesan, S Maity, MC Stein, N Vishnu, MK Venkateswa, JG Davis, K Ramachandr, S Uthayabala, C Allen, A Osidele, K Stanley, NP Bigham, TM Bakewell, M Narkunan, A Le, V Karanam, K Li, A Mhapankar, L Norton, J Ross, MI Aslam, WB Reeves, BB Singh, J Caplan, JJ Wilson, PB Stathopulo, JA Baur, M Madesh
    Cell Reports, 2023-02-27;42(3):112155.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  116. Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures
    Authors: W Song, Y Yang, P Heizer, Y Tu, TA Weston, JR Kim, P Munguia, H Jung, JL Fong, C Tran, M Ploug, AP Beigneux, SG Young, LG Fong
    Proceedings of the National Academy of Sciences of the United States of America, 2023-02-14;120(8):e2219833120.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  117. SARS-CoV-2 triggers pericyte-mediated cerebral capillary constriction
    Authors: Chanawee Hirunpattarasilp, Greg James, Jaturon Kwanthongdee, Felipe Freitas, Jiandong Huo, Huma Sethi et al.
    Brain
  118. IFN-?-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury
    Authors: Wang J, Xu L, Peng D et al.
    Inflammation and regeneration
  119. A refined protocol for the isolation and monoculture of primary mouse renal peritubular endothelial cells
    Authors: Austin D. Thompson, Jaroslav Janda, Rick G. Schnellmann
    Frontiers in Cardiovascular Medicine
  120. Mitochondrial ATP Production is Required for Endothelial Cell Control of Vascular Tone
    Authors: Calum Wilson, Matthew D Lee, Charlotte Buckley, Xun Zhang, John G McCarron
    Function (Oxf)
  121. Gasdermin D inhibition ameliorates neutrophil mediated brain damage in acute ischemic stroke
    Authors: Hu R, Liang J, Ding L et al.
    Cell death discovery
  122. Bone metastasis initiation is coupled with bone remodeling through osteogenic differentiation of NG2+ cells
    Authors: W Zhang, Z Xu, X Hao, T He, J Li, Y Shen, K Liu, Y Gao, J Liu, D Edwards, AM Muscarella, L Wu, L Yu, L Xu, X Chen, YH Wu, IL Bado, Y Ding, S Aguirre, H Wang, Z Gugala, RL Satcher, ST Wong, XH Zhang
    Cancer Discovery, 2023-02-06;0(0):.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  123. Antinociceptive Effects of Aaptamine, a Sponge Component, on Peripheral Neuropathy in Rats
    Authors: CS Sung, HJ Cheng, NF Chen, SH Tang, HM Kuo, PJ Sung, WF Chen, ZH Wen
    Marine Drugs, 2023-02-04;21(2):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  124. Upadacitinib inhibits corneal inflammation and neovascularization by suppressing M1 macrophage infiltration in the corneal alkali burn model
    Authors: J Yu, Y Shen, J Luo, J Jin, P Li, P Feng, H Guan
    International immunopharmacology, 2023-02-03;116(0):109680.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  125. White-light crosslinkable milk protein bioadhesive with ultrafast gelation for first-aid wound treatment
    Authors: Q Zhu, X Zhou, Y Zhang, D Ye, K Yu, W Cao, L Zhang, H Zheng, Z Sun, C Guo, X Hong, Y Zhu, Y Zhang, Y Xiao, TG Valencak, T Ren, D Ren
    Biomaterials research, 2023-02-03;27(1):6.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  126. Improving anti-tumor efficacy of low-dose Vincristine in rhabdomyosarcoma via the combination therapy with FOXM1 inhibitor RCM1
    Authors: Donovan J, Deng Z, Bian F et al.
    Frontiers in oncology
  127. In vitro assessment of varying peptide surface density on the suppression of angiogenesis by micelles displaying alpha v beta 3 blocking peptides
    Authors: Neha Phani Bhushan, Trevor Stack, Evan A. Scott, Kenneth R. Shull, Benjamin Mathew, Divya Bijukumar
    Journal of Biomedical Materials Research Part B: Applied Biomaterials
  128. Somatic GJA4 gain-of-function mutation in orbital cavernous venous malformations
    Authors: Hiroki Hongo, Satoru Miyawaki, Yu Teranishi, Jun Mitsui, Hiroto Katoh, Daisuke Komura et al.
    Angiogenesis
  129. A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts
    Authors: Artur Filipe Rodrigues, Catarina Rebelo, Susana Simões, Cristiana Paulo, Sónia Pinho, Vítor Francisco et al.
    Advanced Science
  130. An Engineered IFNgamma-Antibody Fusion Protein with Improved Tumor-Homing Properties
    Authors: C Di Nitto, E Gilardoni, J Mock, L Nadal, T Weiss, M Weller, F Seehusen, C Libbra, E Puca, D Neri, R De Luca
    Pharmaceutics, 2023-01-22;15(2):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  131. Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis during long bone growth
    Authors: Annemarie Lang, Andreas Benn, Angelique Wolter, Tim Balcaen, Joseph Collins, Greet Kerckhofs et al.
    bioRxiv
  132. Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells
    Authors: Yang Luo, Fei Yao, Yi Shi, Zhenyu Zhu, Zhaoming Xiao, Xingyu You et al.
    Fluids and Barriers of the CNS
  133. Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway
    Authors: Chun-Yue Duan, Jian-Zhong Sheng, Cheng-Jun Zhao, Xiao-Long Sheng, Cheng-Jun Li, Guo-Yu Qin et al.
    Neural Regeneration Research
  134. Knockout of Sirt2 alleviates traumatic brain injury in mice
    Authors: Heng-Li Tian, Qiu-Yuan Wang, Qiu-Yuan Gong, Lin Jing, Dian-Xu Jing, Dian-Xu Yang et al.
    Neural Regeneration Research
  135. Amyloid beta induces cardiac dysfunction and neuro-signaling impairment in the heart of an Alzheimer’s disease model
    Authors: Elia, A;Parodi-Rullan, R;Vazquez-Torres, R;Carey, A;Javadov, S;Fossati, S;
    bioRxiv
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  136. Inhibiting phosphatase and actin regulator 1 expression is neuroprotective in the context of traumatic brain injury
    Authors: Heng-Li Tian, Zhi-Ming Zhang, Shi-Wen Ding, Yao Jing, Shi-Ming Zhang, Shi-Wen Chen et al.
    Neural Regeneration Research
  137. Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice
    Authors: Peng Zhao, Yuanzhong Xu, Xuejun Fan, Leike Li, Xin Li, Hisashi Arase et al.
    mAbs
  138. Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model
    Authors: Peng Zhao, Yasuaki Anami, Peng Gao, Xuejun Fan, Leike Li, Kyoji Tsuchikama et al.
    mAbs
  139. Extracellular vesicle-derived CircWhsc1 Promotes Cardiomyocyte Proliferation and Heart Repair by activating TRIM59/STAT3/Cyclin B2 pathway
    Authors: G Wei, C Li, X Jia, J Xie, Z Tang, M Jin, Q Chen, Y Sun, S He, X Li, Y Chen, H Zheng, W Liao, Y Liao, J Bin, S Huang
    Journal of advanced research, 2022-12-29;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC/IF, IHC/IF
  140. Cyclin G2 in macrophages triggers CTL-mediated antitumor immunity and antiangiogenesis via interferon-gamma
    Authors: Lu Liu, Jinlan Gao, Xuesha Xing, Meixi Jiang, Qi Liu, Shusen Wang et al.
    Journal of Experimental & Clinical Cancer Research
  141. Role of pericytes in the development of cerebral cavernous malformations
    Authors: Zifeng Dai, Jingwei Li, Ying Li, Rui Wang, Huili Yan, Ziyu Xiong et al.
    iScience
  142. Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity
    Authors: Luis F. Martins, Ilaria Brambilla, Alessia Motta, Stefano de Pretis, Ganesh Parameshwar Bhat, Aurora Badaloni et al.
    Neuron
  143. Secretome from human adipose-derived mesenchymal stem cells promotes blood vessel formation and pericyte coverage in experimental skin repair
    Authors: BM Silveira, TO Ribeiro, RS Freitas, ACO Carreira, MS Gonçalves, M Sogayar, R Meyer, A Birbrair, V Fortuna
    PLoS ONE, 2022-12-19;17(12):e0277863.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  144. Immuno-localization of definitive hematopoietic stem cells in the vascular niche of mouse fetal liver
    Authors: Atreyi Biswas, Shailendra Kumar Singh, Gayathri M. Kartha, Satish Khurana
    STAR Protocols
  145. Piperlongumine alleviates corneal allograft rejection via suppressing angiogenesis and inflammation
    Authors: Xiangyu Fan, Jini Qiu, Tianjie Yuan, Jing Zhang, Jianjiang Xu
    Frontiers in Immunology
  146. Microglia regulate central nervous system myelin growth and integrity
    Authors: NB McNamara, DAD Munro, N Bestard-Cu, A Uyeda, JFJ Bogie, A Hoffmann, RK Holloway, I Molina-Gon, KE Askew, S Mitchell, W Mungall, M Dodds, C Dittmayer, J Moss, J Rose, S Szymkowiak, L Amann, BW McColl, M Prinz, TL Spires-Jon, W Stenzel, K Horsburgh, JJA Hendriks, C Pridans, R Muramatsu, A Williams, J Priller, VE Miron
    Nature, 2022-12-14;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  147. Three-dimensional heart extracellular matrix enhances chemically induced direct cardiac reprogramming
    Authors: Y Jin, H Kim, S Min, YS Choi, SJ Seo, E Jeong, SK Kim, HA Lee, SH Jo, JH Park, BW Park, WS Sim, JJ Kim, K Ban, YG Kim, HJ Park, SW Cho
    Science Advances, 2022-12-14;8(50):eabn5768.
    Species: Rat
    Sample Types: Tissue Homogenate
    Applications: IHC
  148. Exosomal miR-532-5p induced by long-term exercise rescues blood-brain barrier function in 5XFAD mice via downregulation of EPHA4
    Authors: X Liang, W Fa, N Wang, Y Peng, C Liu, M Zhu, N Tian, Y Wang, X Han, C Qiu, T Hou, Y Du
    Aging Cell, 2022-12-09;0(0):e13748.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  149. Conserved YKL-40 changes in mice and humans after postoperative delirium
    Authors: Jennifer David-Bercholz, Leah Acker, Ana I. Caceres, Pau Yen Wu, Saanvi Goenka, Nathan O. Franklin et al.
    Brain, Behavior, & Immunity - Health
  150. Novel localization of folate transport systems in the murine central nervous system
    Authors: Vishal Sangha, Md. Tozammel Hoque, Jeffrey T. Henderson, Reina Bendayan
    Fluids and Barriers of the CNS
  151. Angiopoietin-like 2 is essential to aortic valve development in mice
    Authors: Pauline Labbé, Victoria Munoz Goyette, Nathalie Thorin-Trescases, Louis Villeneuve, Ines Desanlis, Constance Delwarde et al.
    Communications Biology
  152. Optical Tissue Clearing to Study the Intra-Pulmonary Biodistribution of Intravenously Delivered Mesenchymal Stromal Cells and Their Interactions with Host Lung Cells
    Authors: Alejandra Hernandez Pichardo, Francesco Amadeo, Bettina Wilm, Raphaël Lévy, Lorenzo Ressel, Patricia Murray et al.
    International Journal of Molecular Sciences
  153. Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration
    Authors: C Lin, Q Yang, D Guo, J Xie, YS Yang, S Chaugule, N DeSouza, WT Oh, R Li, Z Chen, AA John, Q Qiu, LJ Zhu, MB Greenblatt, S Ghosh, S Li, G Gao, C Haynes, CP Emerson, JH Shim
    Nature Communications, 2022-11-11;13(1):6869.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  154. Identification of hematopoietic stem cells residing in the meninges of adult mice at steady state
    Authors: C Niu, J Yu, T Zou, Y Lu, L Deng, H Yun, CY Si, X Wu, H Jiang, T Guo, M Wu, T Kan, J Feng, C Yuan, X Yang, Q Cheng, J Dong, Q Wang, J Zhang
    Cell Reports, 2022-11-08;41(6):111592.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  155. Synaptic pruning through glial synapse engulfment upon motor learning
    Authors: YM Morizawa, M Matsumoto, Y Nakashima, N Endo, T Aida, H Ishikane, K Beppu, S Moritoh, H Inada, N Osumi, E Shigetomi, S Koizumi, G Yang, H Hirai, K Tanaka, KF Tanaka, N Ohno, Y Fukazawa, K Matsui
    Nature Neuroscience, 2022-11-01;25(11):1458-1469.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  156. Ninjurin1 Deletion in NG2-Positive Pericytes Prevents Microvessel Maturation and Delays Wound Healing
    Authors: Risa Matsuo, Mari Kishibe, Kiwamu Horiuchi, Kohei Kano, Takamitsu Tatsukawa, Taiki Hayasaka et al.
    JID Innovations
  157. Continuous sensing of IFNalpha by hepatic endothelial cells shapes a vascular antimetastatic barrier
    Authors: NL Tran, LM Ferreira, B Alvarez-Mo, V Buttiglion, B Ferrini, P Zordan, A Monestirol, C Fagioli, E Bezzecchi, GM Scotti, A Esposito, R Leone, C Gnasso, A Brendolan, LG Guidotti, G Sitia
    Elife, 2022-10-25;11(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  158. Copper promotes cardiac functional recovery via suppressing the transformation of fibroblasts to myofibroblasts in ischemia-infarcted monkey hearts
    Authors: Y Xiao, Q Feng, L Huang, X Meng, P Han, W Zhang, YJ Kang
    The Journal of nutritional biochemistry, 2022-10-12;0(0):109180.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  159. Investigating the role of receptor interacting protein kinase 3 in venous thrombosis
    Authors: Elise DeRoo, Mitri Khoury, Ting Zhou, Huan Yang, Amelia Stranz, Catherine Luke et al.
    JVS-Vascular Science
  160. Single-cell spatial transcriptomics reveals a dynamic control of metabolic zonation and liver regeneration by endothelial cell Wnt2 and Wnt9b
    Authors: Shikai Hu, Silvia Liu, Yu Bian, Minakshi Poddar, Sucha Singh, Catherine Cao et al.
    Cell Reports Medicine
  161. Single-cell transcriptomics reveals functionally specialized vascular endothelium in brain
    Authors: Hyun-Woo Jeong, Rodrigo Diéguez-Hurtado, Hendrik Arf, Jian Song, Hongryeol Park, Kai Kruse et al.
    eLife
  162. Multiscale profiling of protease activity in cancer
    Authors: AP Amini, JD Kirkpatric, CS Wang, AM Jaeger, S Su, S Naranjo, Q Zhong, CM Cabana, T Jacks, SN Bhatia
    Nature Communications, 2022-10-03;13(1):5745.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  163. A single intravenous injection of cyclosporin A-loaded lipid nanocapsules prevents retinopathy of prematurity
    Authors: M Bohley, AE Dillinger, F Schweda, A Ohlmann, BM Braunger, ER Tamm, A Goepferich
    Science Advances, 2022-09-23;8(38):eabo6638.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  164. Expanding tubular microvessels on stiff substrates with endothelial cells and pericytes from the same adult tissue
    Authors: Xiuyue Song, Yali Yu, Yu Leng, Lei Ma, Jie Mu, Zihan Wang et al.
    J Tissue Eng
  165. Single-cell RNA sequencing reveals dysregulation of spinal cord cell types in a severe spinal muscular atrophy mouse model
    Authors: J Sun, J Qiu, Q Yang, Q Ju, R Qu, X Wang, L Wu, L Xing
    PloS Genetics, 2022-09-08;18(9):e1010392.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC fixed frozen
  166. Regulator of G-protein signaling 1 promotes choroidal neovascularization in age-related macular degeneration
    Authors: Qi Zhang, Fengbin Zhang, Yangchen Guo, Yanyan Liu, Ningxin Pan, Hong Chen et al.
    Annals of Translational Medicine
  167. Biofabricated macrophage and fibroblast membranes synergistically promote skin wound healing
    Authors: Dongqing Wang, Heying Chen, Li Lei, Jun Chen, Jimin Gao, Jiahe Liu et al.
    Bioengineering & Translational Medicine
  168. The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation
    Authors: KJ Smith, D Minns, BJ McHugh, RK Holloway, R O'Connor, A Williams, L Melrose, R McPherson, VE Miron, DJ Davidson, E Gwyer Find
    PloS Biology, 2022-08-26;20(8):e3001554.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  169. Pazopanib Is a Potential Treatment for Coronavirus-Induced Lung Injuries
    Authors: Yi Luan, Qianying Yuan, Qijun Wang, Susan Compton, Dianqing Wu, Wenwen Tang
    The Journal of Immunology
  170. Sourcing of human peripheral blood-derived myeloid angiogenic cells under xeno-free conditions for the treatment of critical limb ischemia
    Authors: Christy Wing Tung Wong, Apurva Sawhney, Yalan Wu, Yi Wah Mak, Xiao Yu Tian, Hon Fai Chan et al.
    Stem Cell Research & Therapy
  171. Polyvinyl alcohol coating prevents platelet adsorption and improves mechanical property of polycaprolactone-based small-caliber vascular graft
    Authors: Naohiro Wakabayashi, Takumi Yoshida, Kyohei Oyama, Daisuke Naruse, Masahiro Tsutsui, Yuta Kikuchi et al.
    Frontiers in Cardiovascular Medicine
  172. Macrophages in close proximity to the vitreoretinal interface are potential biomarkers of inflammation during retinal vascular disease
    Authors: A Rajesh, S Droho, JA Lavine
    Journal of Neuroinflammation, 2022-08-08;19(1):203.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  173. CNS Organoid Surpasses Cell-Laden Microgel Assembly to Promote Spinal Cord Injury Repair
    Authors: Zitian Wang, Haoran Zhao, Xiaowei Tang, Tianyu Meng, Davit Khutsishvili, Bing Xu et al.
    Research (Wash D C)
  174. Temporal alteration of microglia to microinfarcts in rat brain induced by the vascular occlusion with fluorescent microspheres
    Authors: Y Shen, J Cui, S Zhang, Y Wang, J Wang, Y Su, D Xu, Y Liu, Y Guo, W Bai
    Frontiers in Cellular Neuroscience, 2022-08-03;16(0):956342.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  175. Brown-fat-mediated tumour suppression by cold-altered global metabolism
    Authors: T Seki, Y Yang, X Sun, S Lim, S Xie, Z Guo, W Xiong, M Kuroda, H Sakaue, K Hosaka, X Jing, M Yoshihara, L Qu, X Li, Y Chen, Y Cao
    Nature, 2022-08-03;608(7922):421-428.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  176. Conserved meningeal lymphatic drainage circuits in mice and humans
    Authors: Laurent Jacob, Jose de Brito Neto, Stephanie Lenck, Celine Corcy, Farhat Benbelkacem, Luiz Henrique Geraldo et al.
    Journal of Experimental Medicine
  177. Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner
    Authors: Mark Richards, Emmanuel Nwadozi, Sagnik Pal, Pernilla Martinsson, Mika Kaakinen, Marleen Gloger et al.
    eLife
  178. Direct reprogramming of adult adipose-derived regenerative cells toward cardiomyocytes using six transcriptional factors
    Authors: Shingo Narita, Kazumasa Unno, Katsuhiro Kato, Yusuke Okuno, Yoshitaka Sato, Yusuke Tsumura et al.
    iScience
  179. Unbalanced Regulation of Sec22b and Ykt6 Blocks Autophagosome Axonal Retrograde Flux in Neuronal Ischemia–Reperfusion Injury
    Authors: Haiying Li, Xiang Li, Zhongmou Xu, Jinxin Lu, Chang Cao, Wanchun You et al.
    The Journal of Neuroscience
  180. DOCK4 Regulation of Rho GTPases Mediates Pulmonary Vascular Barrier Function
    Authors: Pascal Yazbeck, Xavier Cullere, Paul Bennett, Vijay Yajnik, Huan Wang, Kenji Kawada et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  181. Transcriptional profiling reveals roles of intercellular Fgf9 signaling in astrocyte maturation and synaptic refinement during brainstem development
    Authors: AN Brandebura, DR Kolson, EM Amick, J Ramadan, MC Kersting, RH Nichol, PS Holcomb, PH Mathers, P Stoilov, GA Spirou
    The Journal of Biological Chemistry, 2022-06-23;0(0):102176.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  182. Aquaporin 4 Depolarization-Enhanced Transferrin Infiltration Leads to Neuronal Ferroptosis after Subarachnoid Hemorrhage in Mice
    Authors: Y Liu, Z Wang, C Cao, Z Xu, J Lu, H Shen, X Li, H Li, J Wu, G Chen
    Oncogene, 2022-06-17;2022(0):8808677.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  183. The myosin II inhibitor, blebbistatin, ameliorates pulmonary endothelial barrier dysfunction in acute lung injury inducedB19 by LPS via NMMHC IIA/Wnt5a/beta-catenin pathway
    Authors: J Zhang, Z Pan, J Zhou, L Zhang, J Tang, S Gong, F Li, B Yu, Y Zhang, J Kou
    Oncogene, 2022-06-15;0(0):116132.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  184. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia
    Authors: D Xia, S Lianoglou, T Sandmann, M Calvert, JH Suh, E Thomsen, J Dugas, ME Pizzo, SL DeVos, TK Earr, CC Lin, S Davis, C Ha, AW Leung, H Nguyen, R Chau, E Yulyanings, I Lopez, H Solanoy, ST Masoud, CC Liang, K Lin, G Astarita, N Khoury, JY Zuchero, RG Thorne, K Shen, S Miller, JJ Palop, D Garceau, M Sasner, JD Whitesell, JA Harris, S Hummel, J Gnörich, K Wind, L Kunze, A Zatcepin, M Brendel, M Willem, C Haass, D Barnett, TS Zimmer, AG Orr, K Scearce-Le, JW Lewcock, G Di Paolo, PE Sanchez
    Molecular Neurodegeneration, 2022-06-11;17(1):41.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  185. Analysis of the expression, function and signaling of glycogen phosphorylase isoforms in hepatocellular carcinoma
    Authors: L Jiang, S Liu, T Deng, Y Yang, Y Zhang
    Oncology Letters, 2022-06-07;24(2):244.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  186. Combination of Radiofrequency Ablation With Resiquimod to Treat Hepatocellular Carcinoma Via Inflammation of Tumor Immune Microenvironment and Suppression of Angiogenesis
    Authors: Zhou Tian, Baojian Hong, Jianzhong Chen, Zhe Tang
    Frontiers in Oncology
  187. Ciliary IFT88 Protects Coordinated Adolescent Growth Plate Ossification From Disruptive Physiological Mechanical Forces
    Authors: Clarissa R Coveney, Hasmik J Samvelyan, Jadwiga Miotla‐Zarebska, Josephine Carnegie, Emer Chang, C Jonty Corrin et al.
    Journal of Bone and Mineral Research
  188. VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
    Authors: Vinton W.T. Cheng, Nicholas de Pennington, Rasheed Zakaria, James R. Larkin, Sébastien Serres, Manjima Sarkar et al.
    Clinical Cancer Research
  189. Organization of sympathetic innervation of interscapular brown adipose tissue in the mouse
    Authors: Clara Huesing, Rui Zhang, Sanjeev Gummadi, Nathan Lee, Emily Qualls‐Creekmore, Sangho Yu et al.
    Journal of Comparative Neurology
  190. Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition
    Authors: G Huang, Z Cheng, A Hildebrand, C Wang, M Cimini, R Roy, AM Lucchese, C Benedict, V Mallaredy, A Magadum, D Joladarash, C Thej, C Gonzalez, M Trungcao, VNS Garikipati, JW Elrod, WJ Koch, R Kishore
    Theranostics, 2022-05-21;12(9):4415-4430.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  191. A high-efficiency AAV for endothelial cell transduction throughout the central nervous system
    Authors: Trevor Krolak, Ken Y. Chan, Luke Kaplan, Qin Huang, Jason Wu, Qingxia Zheng et al.
    Nature Cardiovascular Research
  192. RhoBTB1 reverses established arterial stiffness in angiotensin-II hypertension by promoting actin depolymerization
    Authors: S Fang, J Wu, JJ Reho, KT Lu, DT Brozoski, G Kumar, AM Werthman, SD Silva, PC Muskus Vei, KK Wackman, AJ Mathison, BQ Teng, CW Lin, FW Quelle, CD Sigmund
    JCI Insight, 2022-05-09;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF/IHC
  193. The transcription factor complex LMO2/TAL1 regulates branching and endothelial cell migration in sprouting angiogenesis
    Authors: Y Yamada, Y Zhong, S Miki, A Taura, TH Rabbitts
    Scientific Reports, 2022-05-04;12(1):7226.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  194. Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice
    Authors: N Tisch, C Mogler, A Stojanovic, R Luck, EA Korhonen, A Ellerkmann, H Adler, M Singhal, G Schermann, L Erkert, JV Patankar, A Karakatsan, AL Scherr, Y Fuchs, A Cerwenka, S Wirtz, BC Köhler, HG Augustin, C Becker, T Schmidt, C Ruiz de Al
    Embo Molecular Medicine, 2022-05-02;0(0):e14121.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  195. Fiber‐Optic Theranostics (FOT): Interstitial Fiber‐Optic Needles for Cancer Sensing and Therapy
    Authors: Yang Ran, Zhiyuan Xu, Minfeng Chen, Wei Wang, Yang Wu, Jiexuan Cai et al.
    Advanced Science
  196. Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
    Authors: Swathi Ayloo, Christopher Gallego Lazo, Shenghuan Sun, Wei Zhang, Bianxiao Cui, Chenghua Gu
    Neuron
  197. Gene therapy with Pellino-1 improves perfusion and decreases tissue loss in Flk-1 heterozygous mice but fails in MAPKAP Kinase-2 knockout murine hind limb ischemia model
    Authors: Mahesh Thirunavukkarasu, Seetur R. Pradeep, Gopi Ukani, Salim Abunnaja, Mark Youssef, Diego Accorsi et al.
    Microvascular Research
  198. Environmental eustress improves postinfarction cardiac repair via enhancing cardiac macrophage survival
    Authors: PY Bai, SQ Chen, DL Jia, LH Pan, CB Liu, J Liu, W Luo, Y Yang, MY Sun, NF Wan, WW Rong, AJ Sun, JB Ge
    Science Advances, 2022-04-27;8(17):eabm3436.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Western Blot
  199. SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRbeta pathway
    Authors: Z Li, S Yu, Y Liu, X Hu, Y Li, Z Xiao, Y Chen, D Tian, X Xu, L Cheng, M Zheng, J Jing
    Journal of Neuroinflammation, 2022-04-16;19(1):95.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  200. Vascular derived endothelin receptor A controls endothelin-induced retinal ganglion cell death
    Authors: Olivia J. Marola, Gareth R. Howell, Richard T. Libby
    Cell Death Discovery
  201. 2-Methoxyestradiol Inhibits Radiation-Induced Skin Injuries
    Authors: JH Kim, JK Nam, AR Kim, MS Park, HJ Lee, J Park, J Kim, YJ Lee
    International Journal of Molecular Sciences, 2022-04-10;23(8):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC/IF
  202. Quantifying Tumor Heterogeneity via MRI Habitats to Characterize Microenvironmental Alterations in HER2+ Breast Cancer
    Authors: AS Kazerouni, DA Hormuth, T Davis, MJ Bloom, S Mounho, G Rahman, J Virostko, TE Yankeelov, AG Sorace
    Cancers, 2022-04-06;14(7):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  203. Rebuilding hippocampus neural circuit with hADSC-derived neuron cells for treating ischemic stroke
    Authors: J Wang, R Hao, T Jiang, X Guo, F Zhou, L Cao, F Gao, G Wang, J Wang, K Ning, C Zhong, X Chen, Y Huang, J Xu, S Gao
    Cell & bioscience, 2022-04-04;12(1):40.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  204. A novel mechanism for A-to-I RNA-edited AZIN1 in promoting tumor angiogenesis in colorectal cancer
    Authors: Y Wei, H Zhang, Q Feng, S Wang, Y Shao, J Wu, G Jin, W Lin, X Peng, X Xu
    Cell Death & Disease, 2022-04-02;13(4):294.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  205. Tibial cortex transverse transport accelerates wound healing via enhanced angiogenesis and immunomodulation
    Authors: Yongkang Yang, Yucong Li, Qi Pan, Shanshan Bai, Haixing Wang, Xiao-hua Pan et al.
    Bone & Joint Research
  206. Melatonin exerts anti-angiogenic and anti-inflammatory effects in alkali-burned corneas
    Authors: Meng J, Lin B, Huang S et al.
    Annals of Translational Medicine
  207. Orchestration of energy metabolism and osteogenesis by Mg2+ facilitates low-dose BMP-2-driven regeneration
    Authors: S Lin, S Yin, J Shi, G Yang, X Wen, W Zhang, M Zhou, X Jiang
    Bioactive materials, 2022-03-24;18(0):116-127.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  208. Endothelial Transient Receptor Potential Canonical Channel Regulates Angiogenesis and Promotes Recovery After Myocardial Infarction
    Authors: X Wen, Y Peng, M Gao, Y Zhu, Y Zhu, F Yu, T Zhou, J Shao, L Feng, X Ma
    Journal of the American Heart Association, 2022-03-05;11(6):e023678.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: ICC/IF
  209. MicroRNA-140-5p exacerbates vascular cognitive impairment by inhibiting neurogenesis in the adult mouse hippocampus after global cerebral ischemia
    Authors: HB Liang, ZH Lai, XQ Tu, KQ Ding, JR He, GY Yang, H Sheng, LL Zeng
    Brain research bulletin, 2022-03-04;183(0):73-83.
    Species: Mouse
    Sample Types: Whole Tissues
    Applications: IHC
  210. Ionizing Radiation-Induced GDF15 Promotes Angiogenesis in Human Glioblastoma Models by Promoting VEGFA Expression Through p-MAPK1/SP1 Signaling
    Authors: Hyejin Park, Ki-Seok Nam, Hae-June Lee, Kwang Seok Kim
    Frontiers in Oncology
  211. Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice
    Authors: Qiu-Yuan Chen, Heng-Li Tian, Qiu-Yuan Gong, Lin Wang, Dian-Xu Jing, Shi-Wen Wang et al.
    Neural Regeneration Research
  212. Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice
    Authors: Guo-Yuan Yang, Ji-Xian Wang, Li-Dong Deng, Sheng-Ju Qi, Muyassar Mamtilahun, Sheng-Ju Shi et al.
    Neural Regeneration Research
  213. Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis
    Authors: S Gao, L Zhou, J Lu, Y Fang, H Wu, W Xu, Y Pan, J Wang, X Wang, J Zhang, A Shao
    Oxidative Medicine and Cellular Longevity, 2022-02-09;2022(0):4295208.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF
  214. ASK1 signaling regulates phase-specific glial interactions during neuroinflammation
    Authors: Xiaoli Guo, Atsuko Kimura, Kazuhiko Namekata, Chikako Harada, Nobutaka Arai, Kohsuke Takeda et al.
    Proceedings of the National Academy of Sciences
  215. Engineered Lung Tissues Prepared from Decellularized Lung Slices
    Authors: Katherine L. Leiby, Ronald Ng, Stuart G. Campbell, Laura E. Niklason
    Journal of Visualized Experiments
  216. Customized blood-brain barrier shuttle peptide to increase AAV9 vector crossing the BBB and augment transduction in the brain
    Authors: Xintao Zhang, Zheng Chai, Amanda Lee Dobbins, Michelle S. Itano, Charles Askew, Zhe Miao et al.
    Biomaterials
  217. Normalisation of glucose metabolism by exendin‐4 in the chronic phase after stroke promotes functional recovery in male diabetic mice
    Authors: Ingrid Lovise Augestad, Doortje Dekens, Dimitra Karampatsi, Osama Elabi, Alexander Zabala, Hiranya Pintana et al.
    British Journal of Pharmacology
  218. Soluble Endoglin Stimulates Inflammatory and Angiogenic Responses in Microglia That Are Associated with Endothelial Dysfunction
    Authors: ES Park, S Kim, DC Yao, JPJ Savarraj, HA Choi, PR Chen, E Kim
    International Journal of Molecular Sciences, 2022-01-22;23(3):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  219. Comprehensive Expression Analysis of Cardiac Fibroblast Growth Factor 23 in Health and Pressure-induced Cardiac Hypertrophy
    Authors: Fiona Eitner, Beatrice Richter, Saskia Schwänen, Malgorzata Szaroszyk, Isabel Vogt, Andrea Grund et al.
    Frontiers in Cell and Developmental Biology
  220. Increased expression of osteopontin in subchondral bone promotes bone turnover and remodeling, and accelerates the progression of OA in a mouse model
    Authors: Chuangxin Lin, Zhong Chen, Dong Guo, Laixi Zhou, Sipeng Lin, Changchuan Li et al.
    Aging (Albany NY)
  221. Enhanced proton treatment with a LDLR-ligand peptide-conjugated gold nanoparticles targeting the tumor microenvironment in an infiltrative brain tumor model
    Authors: S Seo, EH Kim, WS Chang, WS Lee, KH Kim, JK Kim
    American journal of cancer research, 2022-01-15;12(1):198-209.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  222. Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis
    Authors: Darian Williams, Marwa Mahmoud, Renfa Liu, Aitor Andueza, Sandeep Kumar, Dong-Won Kang et al.
    eLife
  223. Microglial replacement in the aged brain restricts neuroinflammation following intracerebral hemorrhage
    Authors: X Li, X Gao, W Zhang, M Liu, Z Han, M Li, P Lei, Q Liu
    Cell Death & Disease, 2022-01-10;13(1):33.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  224. M1 macrophages impair tight junctions between endothelial cells after spinal cord injury
    Authors: Y Luo, F Yao, X Hu, Y Li, Y Chen, Z Li, Z Zhu, S Yu, D Tian, L Cheng, M Zheng, J Jing
    Brain research bulletin, 2022-01-04;0(0):.
    Species: Mouse
    Sample Types: Whole Tissues
    Applications: IHC
  225. Implantable Electrical Stimulation at Dorsal Root Ganglions Accelerates Osteoporotic Fracture Healing via Calcitonin Gene‐Related Peptide
    Authors: Jie Mi, Jian‐Kun Xu, Zhi Yao, Hao Yao, Ye Li, Xuan He et al.
    Advanced Science
  226. Minocycline improves the functional recovery after traumatic brain injury via inhibition of aquaporin-4
    Authors: Q Lu, J Xiong, Y Yuan, Z Ruan, Y Zhang, B Chai, L Li, S Cai, J Xiao, Y Wu, P Huang, H Zhang
    International journal of biological sciences, 2022-01-01;18(1):441-458.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  227. Vascular endothelial growth factor-A/vascular endothelial growth factor2 signaling in spinal neurons contributes to bone cancer pain
    Authors: LJ Fan, HM Kan, XT Chen, YY Sun, LP Chen, W Shen
    Molecular pain, 2022-01-01;18(0):1744806922107.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  228. Inhibition of LncRNA Vof-16 expression promotes nerve regeneration and functional recovery after spinal cord injury
    Authors: XM Zhang, LN Zeng, WY Yang, L Ding, KZ Chen, WJ Fu, SQ Zeng, YR Liang, GH Chen, HF Wu
    Neural regeneration research, 2022-01-01;17(1):217-227.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  229. 3D-printed oxygen-releasing scaffolds improve bone regeneration in mice
    Authors: Ashley L. Farris, Dennis Lambrechts, Yuxiao Zhou, Nicholas Y. Zhang, Naboneeta Sarkar, Megan C. Moorer et al.
    Biomaterials
  230. Microglia regulate central nervous system myelin growth and integrity
    Authors: NB McNamara, DAD Munro, N Bestard-Cu, A Uyeda, JFJ Bogie, A Hoffmann, RK Holloway, I Molina-Gon, KE Askew, S Mitchell, W Mungall, M Dodds, C Dittmayer, J Moss, J Rose, S Szymkowiak, L Amann, BW McColl, M Prinz, TL Spires-Jon, W Stenzel, K Horsburgh, JJA Hendriks, C Pridans, R Muramatsu, A Williams, J Priller, VE Miron
    Nature, 2022;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  231. TREM2-independent oligodendrocyte, astrocyte, and T�cell responses to tau and amyloid pathology in mouse models of Alzheimer disease
    Authors: SH Lee, MG Rezzonico, BA Friedman, MH Huntley, WJ Meilandt, S Pandey, YJ Chen, A Easton, Z Modrusan, DV Hansen, M Sheng, CJ Bohlen
    Cell Reports, 2021-12-28;37(13):110158.
    Species: Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  232. E3 ubiquitin ligase mind bomb 1 overexpression reduces apoptosis and inflammation of cardiac microvascular endothelial cells in coronary microvascular dysfunction
    Authors: XF Qin, YG Shan, JH Gao, FX Li, YX Guo
    Cellular Signalling, 2021-12-23;91(0):110223.
    Species: Rat
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC
  233. The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
    Authors: E Azzoni, V Frontera, G Anselmi, C Rode, C James, EM Deltcheva, AS Demian, J Brown, C Barone, A Patelli, JR Harman, M Nicholls, SJ Conway, E Morrissey, SEW Jacobsen, DB Sparrow, AL Harris, T Enver, MFTR de Bruijn
    Cell Reports, 2021-12-14;37(11):110103.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  234. AAV vectors accumulate in the pineal gland after injections into the brain or spinal cord
    Authors: Oswald Steward, Aminata P. Coulibaly, Mariajose Metcalfe, Jamie M. Dam, Kelly M. Yee
    Molecular Therapy - Methods & Clinical Development
  235. Co‐delivery of fibrin‐laminin hydrogel with mesenchymal stem cell spheroids supports skeletal muscle regeneration following trauma
    Authors: Peter Genovese, Anjali Patel, Natalia Ziemkiewicz, Allison Paoli, Joseph Bruns, Natasha Case et al.
    Journal of Tissue Engineering and Regenerative Medicine
  236. Lin11-Isl1-Mec3 Domain Proteins as Mechanotransducers in Endothelial and Vascular Smooth Muscle Cells
    Authors: Alexandra Sporkova, Subhajit Ghosh, Jaafar Al-Hasani, Markus Hecker
    Frontiers in Physiology
  237. Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas
    Authors: S Heino, S Fang, M Lähde, J Högström, S Nassiri, A Campbell, D Flanagan, A Raven, M Hodder, N Nasreddin, HH Xue, M Delorenzi, S Leedham, TV Petrova, O Sansom, K Alitalo
    Science Advances, 2021-11-17;7(47):eabj0512.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  238. Adult spiny mice (Acomys) exhibit endogenous cardiac recovery in response to myocardial infarction
    Authors: Hsuan Peng, Kazuhiro Shindo, Renée R. Donahue, Erhe Gao, Brooke M. Ahern, Bryana M. Levitan et al.
    npj Regenerative Medicine
  239. Chronic Low-Dose Alcohol Consumption Promotes Cerebral Angiogenesis in Mice
    Authors: Jiyu Li, Chun Li, Ethyn G. Loreno, Sumitra Miriyala, Manikandan Panchatcharam, Xiaohong Lu et al.
    Frontiers in Cardiovascular Medicine
  240. Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases
    Authors: J Taranda, G Mathew, K Watrud, N El-Amine, MF Lee, C Elowsky, A Bludova, S Escobar Av, DG Nowak, TL Wee, JE Wilkinson, LC Trotman, P Osten
    Cell Reports, 2021-11-16;37(7):110027.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  241. Development of Surgical and Visualization Procedures to Analyze Vasculatures by Mouse Tail Edema Model
    Authors: Shinji Kumegawa, Gen Yamada, Daiki Hashimoto, Tsuyoshi Hirashima, Mizuki Kajimoto, Kyoichi Isono et al.
    Biological Procedures Online
  242. Biomimetic sponges improve muscle structure and function following volumetric muscle loss
    Authors: Gabriel Haas, Andrew Dunn, Josh Madsen, Peter Genovese, Hannah Chauvin, Jeffrey Au et al.
    Journal of Biomedical Materials Research Part A
  243. Megalencephalic leukoencephalopathy with subcortical cysts is a developmental disorder of the gliovascular unit
    Authors: Alice Gilbert, Xabier Elorza-Vidal, Armelle Rancillac, Audrey Chagnot, Mervé Yetim, Vincent Hingot et al.
    eLife
  244. Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis
    Authors: A Heinrich, B Bhandary, SJ Potter, N Ratner, T DeFalco
    Cell Reports, 2021-10-26;37(4):109885.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  245. Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?
    Authors: Z Zhang, H Na, Q Gan, Q Tao, Y Alekseyev, J Hu, Z Yan, JB Yang, H Tian, S Zhu, Q Li, IM Rajab, JK Blusztajn, B Wolozin, A Emili, X Zhang, T Stein, LA Potempa, WQ Qiu
    Aging Cell, 2021-10-23;0(0):e13501.
    Species: Mouse
    Sample Types: Tissue Lysates, Whole Cells
    Applications: Functional Assay, Western Blot
  246. Radiation-Induced Fibrotic Tumor Microenvironment Regulates Anti-Tumor Immune Response
    Authors: JK Nam, JH Kim, MS Park, EH Kim, J Kim, YJ Lee
    Cancers, 2021-10-19;13(20):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  247. Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies
    Authors: BR Thomson, P Liu, T Onay, J Du, SW Tompson, S Misener, RR Purohit, TL Young, J Jin, SE Quaggin
    Nature Communications, 2021-10-18;12(1):6072.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  248. Histochrome Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting Ferroptosis-Induced Cardiomyocyte Death
    Authors: Ji-Won Hwang, Jae-Hyun Park, Bong-Woo Park, Hyeok Kim, Jin-Ju Kim, Woo-Sup Sim et al.
    Antioxidants (Basel)
  249. Differential Capability of Clinically Employed Dermal Regeneration Scaffolds to Support Vascularization for Tissue Bioengineering
    Authors: C Agostinis, M Spazzapan, R Vuerich, A Balduit, C Stocco, A Mangogna, G Ricci, G Papa, S Zacchigna, R Bulla
    Biomedicines, 2021-10-13;9(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  250. Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases
    Authors: M Kaduri, M Sela, S Kagan, M Poley, H Abumanhal-, P Mora-Raimu, A Ouro, N Dahan, D Hershkovit, J Shklover, J Shainsky-R, Y Buganim, A Schroeder
    Science Advances, 2021-10-06;7(41):eabj5435.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  251. The mechanistic target of rapamycin complex 1 critically regulates the function of mononuclear phagocytes and promotes cardiac remodeling in acute ischemia
    Authors: GuiHao Chen, Vincent Phan, Xiang Luo, Dian J. Cao
    Journal of Molecular and Cellular Cardiology
  252. A Protective Role of Tumor Necrosis Factor Superfamily-15 in Intracerebral Hemorrhage-Induced Secondary Brain Injury
    Authors: Gui-Li Yang, Shizhao Wang, Shu Zhang, Ye Liu, Xiao Liu, Dong Wang et al.
    ASN Neuro
  253. Expression and related mechanisms of miR-330-3p and S100B in an animal model of cartilage injury
    Authors: Wenming Wu, Dongming Liang
    J Int Med Res
  254. Receptor‑selective interleukin‑4 mutein attenuates laser‑induced choroidal neovascularization through the regulation of macrophage polarization in mice
    Authors: Limo Gao, Wenmin Jiang, Haiying Liu, Zhiheng Chen, Yanhui Lin
    Experimental and Therapeutic Medicine
  255. Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells
    Authors: Zheng Fan, Guillermo Turiel, Raphaela Ardicoglu, Moheb Ghobrial, Evi Masschelein, Tea Kocijan et al.
    Cell Metabolism
  256. Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches
    Authors: M Mesnieres, AM Böhm, N Peredo, D Trompet, R Valle-Tenn, M Bajaj, N Corthout, E Nefyodova, R Cardoen, P Baatsen, S Munck, A Nagy, JJ Haigh, S Khurana, CM Verfaillie, C Maes
    Cell Reports, 2021-08-24;36(8):109618.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  257. Moringa Oleifera Seed Extract Concomitantly Supplemented with Chemotherapy Worsens Tumor Progression in Mice with Triple Negative Breast Cancer and Obesity
    Authors: ERM Zunica, S Yang, A Coulter, C White, JP Kirwan, LA Gilmore
    Nutrients, 2021-08-24;13(9):.
    Species: Xenograft
    Sample Types: Whole Tissue
    Applications: IHC
  258. The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner
    Authors: R Luck, A Karakatsan, B Shah, G Schermann, H Adler, J Kupke, N Tisch, HW Jeong, MK Back, F Hetsch, A D'Errico, M De Palma, E Wiedtke, D Grimm, A Acker-Palm, J von Engelh, RH Adams, HG Augustin, C Ruiz de Al
    Cell Reports, 2021-08-17;36(7):109522.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  259. Efficacy and tolerability of Sorafenib plus metronomic chemotherapy S-1 for advanced hepatocellular carcinoma in preclinical and clinical assessments
    Authors: H Suzuki, H Iwamoto, M Nakano, T Nakamura, A Masuda, T Sakaue, T Tanaka, D Nakano, R Kuromatsu, T Niizeki, S Okamura, S Shimose, T Shirono, Y Noda, N Kamachi, H Yano, A Kawaguchi, H Koga, T Torimura
    Translational Oncology, 2021-08-11;14(11):101201.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  260. Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation
    Authors: Georgia Zarkada, Joel P. Howard, Xue Xiao, Hyojin Park, Mathilde Bizou, Severine Leclerc et al.
    Developmental Cell
  261. B cells modulate the expression of MHC-II on cardiac CCR2− macrophages
    Authors: Cibele Rocha-Resende, Fabiana Pani, Luigi Adamo
    Journal of Molecular and Cellular Cardiology
  262. Regional specialization and fate specification of bone stromal cells in skeletal development
    Authors: KK Sivaraj, HW Jeong, B Dharmaling, D Zeuschner, S Adams, M Potente, RH Adams
    Cell Reports, 2021-07-13;36(2):109352.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  263. Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges
    Authors: D Schafflick, J Wolbert, M Heming, C Thomas, M Hartlehner, AL Börsch, A Ricci, S Martín-Sal, X Li, IN Lu, M Pawlak, J Minnerup, JK Strecker, T Seidenbech, SG Meuth, A Hidalgo, A Liesz, H Wiendl, G Meyer Zu H
    Nature Neuroscience, 2021-07-12;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  264. A bivalent cyclic RGD–siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts
    Authors: Lumin Liao, Bohong Cen, Guoxian Li, Yuanyi Wei, Zhen Wang, Wen Huang et al.
    Drug Delivery
  265. The Organization of the Sinoatrial Node Microvasculature Varies Regionally to Match Local Myocyte Excitability
    Authors: Nathan Grainger, Laura Guarina, Robert H Cudmore, L Fernando Santana
    Function (Oxf)
  266. Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin &alpha5
    Authors: M Richards, S Pal, E Sjöberg, P Martinsson, L Venkatrama, L Claesson-W
    Cell Reports, 2021-06-22;35(12):109268.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  267. Lack of APOL1 in proximal tubules of normal human kidneys and proteinuric APOL1 transgenic mouse kidneys
    Authors: NA Blessing, Z Wu, SM Madhavan, JW Choy, M Chen, MK Shin, M Hoek, JR Sedor, JF O'Toole, LA Bruggeman
    PLoS ONE, 2021-06-17;16(6):e0253197.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  268. VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy
    Authors: Jennifer Bosco, Zhiwei Zhou, Sofie Gabriëls, Mayank Verma, Nan Liu, Brian K. Miller et al.
    Molecular Therapy - Methods & Clinical Development
  269. An antibody against L1 cell adhesion molecule inhibits cardiotoxicity by regulating persistent DNA damage
    Authors: JK Nam, AR Kim, SH Choi, JH Kim, KJ Choi, S Cho, JW Lee, HJ Cho, YW Kwon, J Cho, KS Kim, J Kim, HJ Lee, TS Lee, S Bae, HJ Hong, YJ Lee
    Nature Communications, 2021-06-02;12(1):3279.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  270. Endothelial beta 1 Integrin-Mediated Adaptation to Myocardial Ischemia
    Authors: Carina Henning, Anna Branopolski, Paula Follert, Oksana Lewandowska, Aysel Ayhan, Marcel Benkhoff et al.
    Thrombosis and Haemostasis
  271. An Exercise Mimetic Approach to Reduce Poststroke Deconditioning and Enhance Stroke Recovery
    Authors: Matthew W. McDonald, Matthew S. Jeffers, Lama Issa, Anthony Carter, Allyson Ripley, Lydia M. Kuhl et al.
    Neurorehabilitation and Neural Repair
  272. Loss of Transforming Growth Factor Beta Signaling in Aortic Smooth Muscle Cells Causes Endothelial Dysfunction and Aortic Hypercontractility
    Authors: Jay Zhu, Stoyan Angelov, Ilkay Alp Alp Yildirim, Hao Wei, Jie Hong Hu, Mark W. Majesky et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  273. m7G Methyltransferase METTL1 Promotes Post-ischemic Angiogenesis via Promoting VEGFA mRNA Translation
    Authors: Yongchao Zhao, Lingqiu Kong, Zhiqiang Pei, Fuhai Li, Chaofu Li, Xiaolei Sun et al.
    Frontiers in Cell and Developmental Biology
  274. Perivascular cell‐derived extracellular vesicles stimulate colorectal cancer revascularization after withdrawal of antiangiogenic drugs
    Authors: Maohua Huang, Minfeng Chen, Ming Qi, Geni Ye, Jinghua Pan, Changzheng Shi et al.
    Journal of Extracellular Vesicles
  275. Serum-Derived Small Extracellular Vesicles From Diabetic Mice Impair Angiogenic Property of Microvascular Endothelial Cells: Role of EZH2
    Authors: Z Cheng, V Naga Srika, MM Truongcao, M Cimini, G Huang, C Wang, C Benedict, C Gonzalez, V Mallaredy, DA Goukassian, SK Verma, R Kishore
    Journal of the American Heart Association, 2021-05-14;10(10):e019755.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  276. Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis
    Authors: H Li, Z Wang, Z Chen, T Ci, G Chen, D Wen, R Li, J Wang, H Meng, R Bryan Bell, Z Gu, G Dotti, Z Gu
    Nature Communications, 2021-05-13;12(1):2773.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: Flow Cytometry, IHC
  277. Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation
    Authors: Maya Schiller, Hilla Azulay-Debby, Nadia Boshnak, Yehezqel Elyahu, Ben Korin, Tamar L. Ben-Shaanan et al.
    Immunity
  278. Sympathetic innervation of inguinal white adipose tissue in the mouse
    Authors: Clara Huesing, Emily Qualls‐Creekmore, Nathan Lee, Marie François, Hayden Torres, Rui Zhang et al.
    Journal of Comparative Neurology
  279. Overexpression of circRNA SNRK targets miR-103-3p to reduce apoptosis and promote cardiac repair through GSK3 beta / beta -catenin pathway in rats with myocardial infarction
    Authors: Yeqian Zhu, Pengcheng Zhao, Ling Sun, Yao Lu, Wenwu Zhu, Jian Zhang et al.
    Cell Death Discovery
  280. Type 2 immunity induced by bladder extracellular matrix enhances corneal wound healing
    Authors: X Wang, L Chung, J Hooks, DR Maestas, A Lebid, JI Andorko, L Huleihel, AF Chin, M Wolf, NT Remlinger, MA Stepp, F Housseau, JH Elisseeff
    Science Advances, 2021-04-16;7(16):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  281. Microglia use TAM receptors to detect and engulf amyloid &beta plaques
    Authors: Y Huang, KE Happonen, PG Burrola, C O'Connor, N Hah, L Huang, A Nimmerjahn, G Lemke
    Nature Immunology, 2021-04-15;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  282. Donor cell memory confers a metastable state of directly converted cells
    Authors: KP Kim, C Li, D Bunina, HW Jeong, J Ghelman, J Yoon, B Shin, H Park, DW Han, JB Zaugg, J Kim, T Kuhlmann, RH Adams, KM Noh, SA Goldman, HR Schöler
    Cell Stem Cell, 2021-04-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  283. 3D reconstruction and histopathological analyses on murine corporal body
    Authors: Daiki Hashimoto, Mizuki Kajimoto, Yuko Ueda, Taiju Hyuga, Kota Fujimoto, Saaya Inoue et al.
    Reproductive Medicine and Biology
  284. Expression and enhancement of FABP4 in septoclasts of the growth plate in FABP5-deficient mouse tibiae
    Authors: Yasuhiko Bando, Nobuko Tokuda, Yudai Ogasawara, Go Onozawa, Arata Nagasaka, Koji Sakiyama et al.
    Histochemistry and Cell Biology
  285. The bone microenvironment invigorates metastatic seeds for further dissemination
    Authors: Weijie Zhang, Igor L. Bado, Jingyuan Hu, Ying-Wooi Wan, Ling Wu, Hai Wang et al.
    Cell
  286. The Inflammatory Profile of CTEPH-Derived Endothelial Cells Is a Possible Driver of Disease Progression
    Authors: VFED Smolders, K Lodder, C Rodríguez, O Tura-Ceide, JA Barberà, JW Jukema, PHA Quax, MJ Goumans, K Kurakula
    Cells, 2021-03-26;10(4):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  287. Regulatory Function of Sympathetic Innervation on the Endo/Lysosomal Trafficking of Acetylcholine Receptor
    Authors: Tatjana Straka, Charlotte Schröder, Andreas Roos, Laxmikanth Kollipara, Albert Sickmann, Marion Patrick Ivey Williams et al.
    Frontiers in Physiology
  288. Synergistic inflammatory signaling by cGAS may be involved in the development of atherosclerosis
    Authors: Guan-Feng Lu, Sheng-Cai Chen, Yuan-Peng Xia, Zi-Ming Ye, Fei Cao, Bo Hu
    Aging (Albany NY)
  289. An organoid-based organ-repurposing approach to treat short bowel syndrome
    Authors: S Sugimoto, E Kobayashi, M Fujii, Y Ohta, K Arai, M Matano, K Ishikawa, K Miyamoto, K Toshimitsu, S Takahashi, K Nanki, Y Hakamata, T Kanai, T Sato
    Nature, 2021-02-24;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  290. Early postnatal interactions between beige adipocytes and sympathetic neurites regulate innervation of subcutaneous fat
    Authors: Jingyi Chi, Zeran Lin, William Barr, Audrey Crane, Xiphias Ge Zhu, Paul Cohen
    eLife
  291. Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma
    Authors: E Jung, M Osswald, M Ratliff, H Dogan, R Xie, S Weil, DC Hoffmann, FT Kurz, T Kessler, S Heiland, A von Deimli, F Sahm, W Wick, F Winkler
    Nature Communications, 2021-02-12;12(1):1014.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  292. Melatonin Promotes Heterotopic Ossification Through Regulation of Endothelial-Mesenchymal Transition in Injured Achilles Tendons in Rats
    Authors: Jie Zhang, Jiajun Tang, Jie Liu, Bo Yan, Bin Yan, Minjun Huang et al.
    Frontiers in Cell and Developmental Biology
  293. Changes of blood-brain-barrier function and transfer of amyloid beta in rats with collagen-induced arthritis
    Authors: PH Lai, TH Wang, NY Zhang, KC Wu, CJ Yao, CJ Lin
    Journal of Neuroinflammation, 2021-01-30;18(1):35.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  294. Single-cell transcriptomics following ischemic injury identifies a role for B2M in cardiac repair
    Authors: Bas Molenaar, Louk T. Timmer, Marjolein Droog, Ilaria Perini, Danielle Versteeg, Lieneke Kooijman et al.
    Communications Biology
  295. CU06-1004-Induced Vascular Normalization Improves Immunotherapy by Modulating Tumor Microenvironment via Cytotoxic T Cells
    Authors: Songyi Park, Ji Hoon Oh, Dong Jin Park, Haiying Zhang, Minyoung Noh, Yeomyung Kim et al.
    Frontiers in Immunology
  296. DL-3n-Butylphthalide Improves Blood-Brain Barrier Integrity in Rat After Middle Cerebral Artery Occlusion
    Authors: M Mamtilahun, Z Wei, C Qin, Y Wang, Y Tang, FX Shen, HL Tian, Z Zhang, GY Yang
    Frontiers in Cellular Neuroscience, 2021-01-12;14(0):610714.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  297. Carbon nano-onion-mediated dual targeting of P-selectin and P-glycoprotein to overcome cancer drug resistance
    Authors: H Wang, Y Liang, Y Yin, J Zhang, W Su, AM White, Bin Jiang, J Xu, Y Zhang, S Stewart, X Lu, X He
    Nature Communications, 2021-01-12;12(1):312.
    Species: Mouse
    Sample Types: Whole Tissues
    Applications: IHC
  298. Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner
    Authors: MM Gladka, A Kohela, B Molenaar, D Versteeg, L Kooijman, J Monshouwer, V Kremer, HR Vos, MMH Huibers, JJ Haigh, D Huylebroec, RA Boon, M Giacca, E van Rooij
    Nature Communications, 2021-01-04;12(1):84.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  299. Apolipoprotein E, low-density lipoprotein receptor, and immune cells control blood-brain barrier penetration by AAV-PHP.eB in mice
    Authors: BS Xie, X Wang, YH Pan, G Jiang, JF Feng, Y Lin
    Theranostics, 2021-01-01;11(3):1177-1191.
    Species: Mouse, Transgenic Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  300. Osteoblasts derived from mouse mandible enhance tumor growth of prostate cancer more than osteoblasts derived from long bone
    Authors: MR Eber, SH Park, KF Contino, CM Patel, FC Hsu, Y Shiozawa
    Journal of Bone Oncology, 2020-12-30;26(0):100346.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  301. An engineered 4-1BBL fusion protein with “activity on demand”
    Authors: Jacqueline Mock, Marco Stringhini, Alessandra Villa, Michael Weller, Tobias Weiss, Dario Neri
    Proceedings of the National Academy of Sciences
  302. Hypergravity as a gravitational therapy mitigates the effects of knee osteoarthritis on the musculoskeletal system in a murine model
    Authors: B Dechaumet, D Cleret, MT Linossier, A Vanden-Bos, S Chanon, E Lefai, N Laroche, MH Lafage-Pro, L Vico
    PLoS ONE, 2020-12-09;15(12):e0243098.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  303. A rapid, nondestructive method for vascular network visualization
    Authors: Austin Veith, Aaron B Baker
    BioTechniques
  304. Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling
    Authors: Y Xiong, MJ Scerbo, A Seelig, F Volta, N O'Brien, A Dicker, D Padula, H Lickert, JM Gerdes, PO Berggren
    Elife, 2020-11-17;9(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  305. Intermedin Alleviates Renal Ischemia-Reperfusion Injury and Enhances Neovascularization in Wistar Rats
    Authors: Y Wang, Y Mi, J Tian, X Qiao, X Su, J Kang, Z Wu, G Wang, X Zhou, Y Zhou, R Li
    Drug Des Devel Ther, 2020-11-10;14(0):4825-4834.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  306. The endothelial protein C receptor plays an essential role in the maintenance of pregnancy
    Authors: MM Castillo, Q Yang, AS Sigala, DT McKinney, M Zhan, KL Chen, JA Jarzembows, R Sood
    Sci Adv, 2020-11-06;6(45):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  307. Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing
    Authors: J Sun, H Feng, W Xing, Y Han, J Suo, AR Yallowitz, N Qian, Y Shi, MB Greenblatt, W Zou
    Sci Adv, 2020-11-04;6(45):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  308. Tendon-derived cathepsin K–expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification
    Authors: Heng Feng, Wenhui Xing, Yujiao Han, Jun Sun, Mingxiang Kong, Bo Gao et al.
    Journal of Clinical Investigation
  309. Apolipoprotein E isoforms differentially regulate matrix metallopeptidase 9 function in Alzheimer’s disease
    Authors: Charis Ringland, Jonas Elias Schweig, Daniel Paris, Ben Shackleton, Cillian E. Lynch, Maxwell Eisenbaum et al.
    Neurobiology of Aging
  310. Intra-cisterna magna delivery of an AAV vector with the GLUT1 promoter in a pig recapitulates the physiological expression of SLC2A1
    Authors: S Nakamura, H Osaka, SI Muramatsu, N Takino, M Ito, EF Jimbo, C Watanabe, S Hishikawa, T Nakajima, T Yamagata
    Gene Ther, 2020-10-19;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  311. Microglia-organized scar-free spinal cord repair in neonatal mice
    Authors: Y Li, X He, R Kawaguchi, Y Zhang, Q Wang, A Monavarfes, Z Yang, B Chen, Z Shi, H Meng, S Zhou, J Zhu, A Jacobi, V Swarup, PG Popovich, DH Geschwind, Z He
    Nature, 2020-10-07;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  312. An injectable hydrogel‐formulated inhibitor of prolyl‐4‐hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis
    Authors: Kosuke Nagai, Hidetaka Ideguchi, Tetsuhiro Kajikawa, Xiaofei Li, Triantafyllos Chavakis, Jing Cheng et al.
    The FASEB Journal
  313. IL-6 Induced by Periodontal Inflammation Causes Neuroinflammation and Disrupts the Blood-Brain Barrier
    Authors: D Furutama, S Matsuda, Y Yamawaki, S Hatano, A Okanobu, T Memida, H Oue, T Fujita, K Ouhara, M Kajiya, N Mizuno, T Kanematsu, K Tsuga, H Kurihara
    Brain Sci, 2020-09-27;10(10):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  314. Endothelin 1-induced retinal ganglion cell death is largely mediated by JUN activation
    Authors: Olivia J. Marola, Stephanie B. Syc-Mazurek, Gareth R. Howell, Richard T. Libby
    Cell Death & Disease
  315. Abrogation of atypical neurogenesis and vascular-derived EphA4 prevents repeated mild TBI-induced learning and memory impairments
    Authors: K Greer, EKG Basso, C Kelly, A Cash, E Kowalski, S Cerna, CT Ocampo, X Wang, MH Theus
    Scientific Reports, 2020-09-21;10(1):15374.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  316. FGFR3 in Periosteal Cells Drives Cartilage-to-Bone Transformation in Bone Repair
    Authors: A Julien, S Perrin, O Duchamp de, C Carvalho, M Bensidhoum, L Legeai-Mal, C Colnot
    Stem Cell Reports, 2020-09-10;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  317. Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells
    Authors: C Donato, L Kunz, F Castro-Gin, A Paasinen-S, K Strittmatt, BM Szczerba, R Scherrer, N Di Maggio, W Heusermann, O Biehlmaier, C Beisel, M Vetter, C Rochlitz, WP Weber, A Banfi, T Schroeder, N Aceto
    Cell Rep, 2020-09-08;32(10):108105.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  318. Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier
    Authors: Zhongxiao Wang, Chi-Hsiu Liu, Shuo Huang, Zhongjie Fu, Yohei Tomita, William R. Britton et al.
    Science Advances
  319. Delayed metformin treatment improves functional recovery following traumatic brain injury via central AMPK-dependent brain tissue repair
    Authors: YY Fan, YJ Wang, J Guo, MN Wu, MS Zhang, BL Niu, Y Li, J Zhao, CH Yang, Y Li, M Chen, XY Jiao
    Brain Res. Bull., 2020-08-26;164(0):146-156.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  320. Developmental changes in myocardial B cells mirror changes in B cells associated with different organs
    Authors: C Rocha-Rese, W Yang, W Li, D Kreisel, L Adamo, DL Mann
    JCI Insight, 2020-08-20;5(16):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  321. Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors
    Authors: K Hosaka, Y Yang, T Seki, Q Du, X Jing, X He, J Wu, Y Zhang, H Morikawa, M Nakamura, M Scherzer, X Sun, Y Xu, T Cheng, X Li, X Liu, Q Li, Y Liu, A Hong, Y Chen, Y Cao
    Nat Commun, 2020-07-24;11(1):3704.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  322. PPAR-&gamma Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats
    Authors: J Li, K Zhang, Q Zhang, X Zhou, L Wen, J Ma, L Niu, C Li
    Biomed Res Int, 2020-07-22;2020(0):8163789.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  323. Co-immunostaining of ICAM-1, ICAM-2, and CD31 in Mouse Kidney Glomeruli
    Authors: Sun-Sang J Sung
    BIO-PROTOCOL
  324. VEGF‐B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content
    Authors: Christine Moessinger, Ingrid Nilsson, Lars Muhl, Manuel Zeitelhofer, Benjamin Heller Sahlgren, Josefin Skogsberg et al.
    EMBO reports
  325. Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function
    Authors: Jianlin Zhang, Kevin P. Vincent, Angela K. Peter, Matthew Klos, Hongqiang Cheng, Selina Manying Huang et al.
    Circulation Research
  326. A lineage-tracing tool to map the fate of hypoxic tumour cells
    Authors: Jenny A. F. Vermeer, Jonathan Ient, Bostjan Markelc, Jakob Kaeppler, Lydie M. O. Barbeau, Arjan J. Groot et al.
    Disease Models & Mechanisms
  327. Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury
    Authors: AL Vivinetto, ID Kim, DC Goldberg, L Fones, E Brown, VS Tarabykin, CE Hill, S Cho, JW Cave
    Cell Rep, 2020-06-30;31(13):107834.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  328. Role of FOXM1 in vascular smooth muscle cell survival and neointima formation following vascular injury
    Authors: S Franco, A Stranz, F Ljumani, G Urabe, M Chaudhary, D Stewart, VS Pilli, M Kelly, D Yamanouchi, KC Kent, B Liu
    Heliyon, 2020-06-16;6(6):e04028.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  329. Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization
    Authors: Jing Zhang, Jonathan Muri, Gillian Fitzgerald, Tatiane Gorski, Roberto Gianni-Barrera, Evi Masschelein et al.
    Cell Metabolism
  330. The Paracrine Role of Endothelial Cells in Bone Formation via CXCR4/SDF-1 Pathway
    Authors: T Tamari, R Kawar-Jara, O Doppelt, B Giladi, N Sabbah, H Zigdon-Gil
    Cells, 2020-05-26;9(6):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  331. Farnesoid X receptor knockout protects brain against ischemic injury through reducing neuronal apoptosis in mice
    Authors: HM Shan, M Zang, Q Zhang, RB Shi, XJ Shi, M Mamtilahun, C Liu, LL Luo, X Tian, Z Zhang, GY Yang, Y Tang, J Pu, Y Wang
    J Neuroinflammation, 2020-05-25;17(1):164.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  332. Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke
    Authors: L Kang, H Yu, X Yang, Y Zhu, X Bai, R Wang, Y Cao, H Xu, H Luo, L Lu, MJ Shi, Y Tian, W Fan, BQ Zhao
    Nat Commun, 2020-05-19;11(1):2488.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  333. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
    Authors: L Wang, CM Cheng, J Qin, M Xu, CY Kao, J Shi, E You, W Gong, LP Rosa, P Chase, L Scampavia, F Madoux, T Spicer, P Hodder, HE Xu, SY Tsai, MJ Tsai
    Sci Adv, 2020-04-29;6(18):eaaz8031.
    Species: Xenograft
    Sample Types: Whole Tissue
    Applications: IHC
  334. Aberrant Differentiation of Human Pluripotent Stem Cell-Derived Kidney Precursor Cells inside Mouse Vascularized Bioreactors
    Authors: Parisa Ranjzad, Jessica Jinks, Amir P. Salahi, Ioannis Bantounas, Brian Derby, Susan J. Kimber et al.
    Nephron
  335. Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb
    Authors: D Zhu, TK Johnson, Y Wang, M Thomas, K Huynh, Q Yang, VC Bond, YE Chen, D Liu
    Stem Cell Res Ther, 2020-04-22;11(1):162.
    Species: Mouse
    Sample Types: Tissue
    Applications: IHC-Fr
  336. Weekends-Off Lenvatinib for Unresectable Hepatocellular Carcinoma Improves Therapeutic Response and Tolerability toward Adverse Events
    Authors: H Iwamoto, H Suzuki, S Shimose, T Niizeki, M Nakano, T Shirono, S Okamura, Y Noda, N Kamachi, T Nakamura, A Masuda, T Sakaue, T Tanaka, D Nakano, M Sakai, T Yamaguchi, R Kuromatsu, H Koga, T Torimura
    Cancers (Basel), 2020-04-19;12(4):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  337. Identification of a novel tumor angiogenesis inhibitor targeting Shh/Gli1 signaling pathway in Non-small cell lung cancer
    Authors: X Lei, Y Zhong, L Huang, S Li, J Fu, L Zhang, Y Zhang, Q Deng, X Yu
    Cell Death Dis, 2020-04-14;11(4):232.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  338. Eradication of tumor growth by delivering novel photothermal selenium-coated tellurium nanoheterojunctions
    Authors: S Chen, C Xing, D Huang, C Zhou, B Ding, Z Guo, Z Peng, D Wang, X Zhu, S Liu, Z Cai, J Wu, J Zhao, Z Wu, Y Zhang, C Wei, Q Yan, H Wang, D Fan, L Liu, H Zhang, Y Cao
    Sci Adv, 2020-04-08;6(15):eaay6825.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  339. Imatinib Sets Pericyte Mosaic in the Retina
    Authors: T Kovács-Öll, E Ivanova, G Szarka, ÁJ Tengölics, B Völgyi, BT Sagdullaev
    Int J Mol Sci, 2020-04-05;21(7):.
    Species: Mouse
    Sample Types: Tissue
    Applications: IHC-P
  340. Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
    Authors: Z Li, EA Korhonen, A Merlini, J Strauss, E Wihuri, H Nurmi, S Antila, J Paech, U Deutsch, B Engelhardt, S Chintharla, GY Koh, A Flügel, K Alitalo
    J. Clin. Invest., 2020-04-01;0(0):.
    Species: Mouse
    Sample Types:
    Applications: IHC-P
  341. Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B
    Authors: Anita Grover, Danielle Crippen-Harmon, Lacey Nave, Jon Vincelette, Jill C. M. Wait, Andrew C. Melton et al.
    Drug Delivery and Translational Research
  342. Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues
    Authors: MB Chen, AC Yang, H Yousef, D Lee, W Chen, N Schaum, B Lehallier, SR Quake, T Wyss-Coray
    Cell Rep, 2020-03-31;30(13):4418-4432.e4.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  343. High Density Display of an Anti-Angiogenic Peptide on Micelle Surfaces Enhances Their Inhibition of alpha v beta 3 Integrin-Mediated Neovascularization In Vitro
    Authors: Rajini Nagaraj, Trevor Stack, Sijia Yi, Benjamin Mathew, Kenneth R Shull, Evan A Scott et al.
    Nanomaterials (Basel)
  344. HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure
    Authors: Beth A Firulli, Rajani M George, Jade Harkin, Kevin P Toolan, Hongyu Gao, Yunlong Liu et al.
    Cardiovascular Research
  345. Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta
    Authors: Eric Engelbrecht, Michel V Levesque, Liqun He, Michael Vanlandewijck, Anja Nitzsche, Hira Niazi et al.
    eLife
  346. MicroRNA-29b-3p inhibits cell proliferation and angiogenesis by targeting VEGFA and PDGFB in retinal microvascular endothelial cells
    Authors: W Tang, J Guo, R Gu, B Lei, X Ding, J Ma, G Xu
    Mol. Vis., 2020-02-24;26(0):64-75.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  347. Mouse retinal cell behaviour in space and time using light sheet fluorescence microscopy
    Authors: Claudia Prahst, Parham Ashrafzadeh, Thomas Mead, Ana Figueiredo, Karen Chang, Douglas Richardson et al.
    eLife
  348. A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder
    Authors: Lynelle K. Jones, Rachel Lam, Karen K. McKee, Maya Aleksandrova, John Dowling, Stephen I. Alexander et al.
    Development
  349. Role of Endothelial ADAM17 in Early Vascular Changes Associated with Diabetic Retinopathy
    Authors: L Shalaby, M Thounaojam, A Tawfik, J Li, K Hussein, WJ Jahng, M Al-Shabraw, HF Kwok, M Bartoli, D Gutsaeva
    J Clin Med, 2020-02-02;9(2):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  350. Plumbagin inhibits tumor angiogenesis of gastric carcinoma in mice by modulating nuclear factor-kappa B pathway
    Authors: Chengqian Yang, Xingbo Feng, Zengxian Li, Qingsi He
    Translational Cancer Research
  351. Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis
    Authors: S Colijn, V Muthukumar, J Xie, S Gao, CT Griffin
    Dis Model Mech, 2020-01-24;13(1):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  352. VEGF-B ablation in pancreatic beta-cells upregulates insulin expression without affecting glucose homeostasis or islet lipid uptake
    Authors: FC Ning, N Jensen, J Mi, W Lindström, M Balan, L Muhl, U Eriksson, I Nilsson, D Nyqvist
    Sci Rep, 2020-01-22;10(1):923.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  353. Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development
    Authors: H Yamamoto, T Kon, Y Omori, T Furukawa
    Cell Rep, 2020-01-21;30(3):658-671.e5.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IF
  354. Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy
    Authors: JH Wu, YN Li, AQ Chen, CD Hong, CL Zhang, HL Wang, YF Zhou, PC Li, Y Wang, L Mao, YP Xia, QW He, HJ Jin, ZY Yue, B Hu
    EMBO Mol Med, 2020-01-13;12(2):e10154.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  355. Non-Invasive Monitoring of Oxygen Tension and Oxygen Transport Inside Subcutaneous Devices After H2S Treatment
    Authors: A Najdahmadi, AM Smink, P de Vos, JRT Lakey, E Botvinick
    Cell Transplant, 2020-01-01;29(0):9636897198939.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  356. Blocking endothelial apoptosis revascularises the retina in a model of ischemic retinopathy
    Authors: ZL Grant, L Whitehead, VHY Wong, Z He, RY Yan, AR Miles, AV Benest, DO Bates, C Prahst, K Bentley, BV Bui, RC Symons, L Coultas
    J. Clin. Invest., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IIHC
  357. Small-molecule inhibitor targeting orphan nuclear receptor COUP-TFII for prostate cancer treatment
    Authors: L Wang, CM Cheng, J Qin, M Xu, CY Kao, J Shi, E You, W Gong, LP Rosa, P Chase, L Scampavia, F Madoux, T Spicer, P Hodder, HE Xu, SY Tsai, MJ Tsai
    Sci Adv, 2020;6(18):eaaz8031.
    Species: Xenograft
    Sample Types: Whole Tissue
    Applications: IHC
  358. Cleaved CD31 as a target for in vivo molecular imaging of inflammation
    Authors: J Vigne, S Bay, R Aid-Launai, G Pariscoat, G Rucher, J Sénémaud, A Truffier, N Anizan, G Even, C Ganneau, F Andreata, M Le Borgne, A Nicoletti, D Le Guludec, G Caligiuri, F Rouzet
    Sci Rep, 2019-12-20;9(1):19560.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  359. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease
    Authors: N Lalaoui, SE Boyden, H Oda, GM Wood, DL Stone, D Chau, L Liu, M Stoffels, T Kratina, KE Lawlor, KJM Zaal, PM Hoffmann, N Etemadi, K Shield-Art, C Biben, WL Tsai, MD Blake, HS Kuehn, D Yang, H Anderton, N Silke, L Wachsmuth, L Zheng, NS Moura, DB Beck, G Gutierrez-, AK Ombrello, GP Pinto-Pata, AJ Kueh, MJ Herold, C Hall, H Wang, JJ Chae, NI Dmitrieva, M McKenzie, A Light, BK Barham, A Jones, TM Romeo, Q Zhou, I Aksentijev, JC Mullikin, AJ Gross, AK Shum, ED Hawkins, SL Masters, MJ Lenardo, M Boehm, SD Rosenzweig, M Pasparakis, AK Voss, M Gadina, DL Kastner, J Silke
    Nature, 2019-12-11;577(7788):103-108.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  360. Endothelial EphB4 maintains vascular integrity and transport function in adult heart
    Authors: G Luxán, J Stewen, N Díaz, K Kato, SK Maney, A Aravamudha, F Berkenfeld, N Nagelmann, HC Drexler, D Zeuschner, C Faber, H Schillers, S Hermann, J Wiseman, JM Vaquerizas, ME Pitulescu, RH Adams
    Elife, 2019-11-29;8(0):.
    Species: Mouse
    Sample Types: Tissue Lysates
    Applications: IHC
  361. Graft immaturity and safety concerns in transplanted human kidney organoids
    Authors: SA Nam, E Seo, JW Kim, HW Kim, HL Kim, K Kim, TM Kim, JH Ju, IG Gomez, K Uchimura, BD Humphreys, CW Yang, JY Lee, J Kim, DW Cho, BS Freedman, YK Kim
    Exp. Mol. Med., 2019-11-28;51(11):145.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  362. Orthopedic Surgery Triggers Attention Deficits in a Delirium-Like Mouse Model
    Authors: Ravikanth Velagapudi, Saraswathi Subramaniyan, Chao Xiong, Fiona Porkka, Ramona M. Rodriguiz, William C. Wetsel et al.
    Frontiers in Immunology
  363. Predicting Angiogenesis by Endothelial Progenitor Cells Relying on In-Vitro Function Assays and VEGFR-2 Expression Levels
    Authors: N Sabbah, T Tamari, R Elimelech, O Doppelt, U Rudich, H Zigdon-Gil
    Biomolecules, 2019-11-08;9(11):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  364. Myc‐dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor‐2
    Authors: Chiara Testini, Ross O Smith, Yi Jin, Pernilla Martinsson, Ying Sun, Marie Hedlund et al.
    EMBO reports
  365. Secreted protein acidic and rich in cysteine mediates active targeting of human serum albumin in U87MG xenograft mouse models
    Authors: CR Park, JH Jo, MG Song, JY Park, YH Kim, H Youn, SH Paek, JK Chung, JM Jeong, YS Lee, KW Kang
    Theranostics, 2019-10-11;9(24):7447-7457.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  366. Engineering transferrable microvascular meshes for subcutaneous islet transplantation
    Authors: W Song, A Chiu, LH Wang, RE Schwartz, B Li, N Bouklas, DT Bowers, D An, SH Cheong, JA Flanders, Y Pardo, Q Liu, X Wang, VK Lee, G Dai, M Ma
    Nat Commun, 2019-10-10;10(1):4602.
    Species: Mouse
    Sample Types: Microvascular Mesh
    Applications: IHC
  367. Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation
    Authors: AA Lombardi, AA Gibb, E Arif, DW Kolmetzky, D Tomar, TS Luongo, P Jadiya, EK Murray, PK Lorkiewicz, G Hajnóczky, E Murphy, ZP Arany, DP Kelly, KB Margulies, BG Hill, JW Elrod
    Nat Commun, 2019-10-04;10(1):4509.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  368. TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding
    Authors: T Wyseure, T Yang, JY Zhou, EJ Cooke, B Wanko, M Olmer, R Agashe, Y Morodomi, N Behrendt, M Lotz, J Morser, A von Drygal, LO Mosnier
    JCI Insight, 2019-10-03;0(0):.
    Species: Human, Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr, IHC-P
  369. Cellular Mechanisms of Angiogenesis in Neonatal Rat Models of Retinal Neurodegeneration
    Authors: D Asano, M Hokazono, S Hirano, A Morita, T Nakahara
    Int J Mol Sci, 2019-09-25;20(19):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  370. Long-term mucosal injury and repair in a murine model of pelvic radiotherapy
    Authors: DK Malipatlol, P Patel, F Sjöberg, S Devarakond, M Kalm, E Angenete, EB Lindskog, R Grandér, L Persson, A Stringer, U Wilderäng, J Swanpalmer, HG Kuhn, G Steineck, C Bull
    Sci Rep, 2019-09-24;9(1):13803.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  371. Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis
    Authors: Venkata Naga Srikanth Garikipati, Suresh Kumar Verma, Zhongjian Cheng, Dongming Liang, May M. Truongcao, Maria Cimini et al.
    Nature Communications
  372. Cardiomyocyte d-dopachrome tautomerase protects against heart failure
    Authors: Y Ma, KN Su, D Pfau, VS Rao, X Wu, X Hu, L Leng, X Du, M Piecychna, K Bedi, SG Campbell, A Eichmann, JM Testani, KB Margulies, R Bucala, LH Young
    JCI Insight, 2019-09-05;4(17):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  373. Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse
    Authors: Jay C. Jha, Aozhi Dai, Chet E. Holterman, Mark E. Cooper, Rhian M. Touyz, Chris R. Kennedy et al.
    Diabetologia
  374. UTX/KDM6A Deletion Promotes Recovery of Spinal Cord Injury by Epigenetically Regulating Vascular Regeneration
    Authors: S Ni, Z Luo, L Jiang, Z Guo, P Li, X Xu, Y Cao, C Duan, T Wu, C Li, H Lu, J Hu
    Mol. Ther., 2019-08-22;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  375. Administration of Tramadol or Buprenorphine via the drinking water for post-operative analgesia in a mouse-osteotomy model
    Authors: P Jirkof, M Durst, R Klopfleisc, R Palme, C Thöne-Rein, F Buttgereit, K Schmidt-Bl, A Lang
    Sci Rep, 2019-07-24;9(1):10749.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  376. Single-cell analysis reveals T cell infiltration in old neurogenic niches
    Authors: BW Dulken, MT Buckley, P Navarro Ne, N Saligrama, R Cayrol, DS Leeman, BM George, SC Boutet, K Hebestreit, JV Pluvinage, T Wyss-Coray, IL Weissman, H Vogel, MM Davis, A Brunet
    Nature, 2019-07-03;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  377. Disruption of the Extracellular Matrix Progressively Impairs Central Nervous System Vascular Maturation Downstream of beta -Catenin Signaling
    Authors: Lasse D. Jensen, Belma Hot, Daniel Ramsköld, Raoul F.V. Germano, Chika Yokota, Sarantis Giatrellis et al.
    Arteriosclerosis, Thrombosis, and Vascular Biology
  378. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes
    Authors: R Diéguez-Hu, K Kato, BD Giaimo, M Nieminen-K, H Arf, F Ferrante, M Bartkuhn, T Zimmermann, MG Bixel, HM Eilken, S Adams, T Borggrefe, P Vajkoczy, RH Adams
    Nat Commun, 2019-06-27;10(1):2817.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  379. Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss
    Authors: AM Nikolakopo, A Montagne, K Kisler, Z Dai, Y Wang, MT Huuskonen, AP Sagare, D Lazic, MD Sweeney, P Kong, M Wang, NC Owens, EJ Lawson, X Xie, Z Zhao, BV Zlokovic
    Nat. Neurosci., 2019-06-24;22(7):1089-1098.
    Species: Transgenic Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  380. Antibody-based delivery of cytokine payloads to carbonic anhydrase IX leads to cancer cures in immunocompetent tumor-bearing mice
    Authors: B Ziffels, M Stringhini, P Probst, T Fugmann, T Sturm, D Neri
    Mol. Cancer Ther., 2019-06-18;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  381. Targeted Delivery of TNF Potentiates the Antibody-Dependent Cell-Mediated Cytotoxicity of an Anti-Melanoma Immunoglobulin
    Authors: Patrizia Murer, Jonathan D. Kiefer, Louis Plüss, Mattia Matasci, Sandra L. Blümich, Marco Stringhini et al.
    Journal of Investigative Dermatology
  382. Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis
    Authors: Lixian Chen, Tianhao Zhou, Nan Wu, April O'Brien, Julie Venter, Ludovica Ceci et al.
    Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  383. Transfusion of Resting Platelets Reduces Brain Hemorrhage After Intracerebral Hemorrhage and tPA-Induced Hemorrhage After Cerebral Ischemia
    Authors: H Luo, L Wei, L Lu, L Kang, Y Cao, X Yang, X Bai, W Fan, BQ Zhao
    Front Neurosci, 2019-04-05;13(0):338.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  384. Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo
    Authors: Bechara Saykali, Navrita Mathiah, Wallis Nahaboo, Marie-Lucie Racu, Latifa Hammou, Matthieu Defrance et al.
    eLife
  385. Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation
    Authors: SG Romeo, KM Alawi, J Rodrigues, A Singh, AP Kusumbe, SK Ramasamy
    Nat. Cell Biol., 2019-04-01;21(4):430-441.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  386. Endothelial cells are a source of Nestin expression in Pulmonary Arterial Hypertension
    Authors: AR Bhagwani, S Hultman, D Farkas, R Moncayo, K Dandamudi, AK Zadu, CD Cool, L Farkas
    PLoS ONE, 2019-03-18;14(3):e0213890.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Selection
  387. Overexpression of LH3 reduces the incidence of hypertensive intracerebral hemorrhage in mice
    Authors: Hao Li, Haochen Xu, Hongyan Wen, Tianlong Liu, Yingying Sun, Ning Xiao et al.
    Journal of Cerebral Blood Flow & Metabolism
  388. Decellularized neonatal cardiac extracellular matrix prevents widespread ventricular remodeling in adult mammals after myocardial infarction
    Authors: Zhouguang Wang, Daniel W. Long, Yan Huang, William C.W. Chen, Kang Kim, Yadong Wang
    Acta Biomaterialia
  389. Human Neonatal Thymus Mesenchymal Stem/Stromal Cells and Chronic Right Ventricle Pressure Overload
    Authors: Josue Chery, Shan Huang, Lianghui Gong, Shuyun Wang, Zhize Yuan, Joshua Wong et al.
    Bioengineering (Basel)
  390. PU.1 controls fibroblast polarization and tissue fibrosis
    Authors: T Wohlfahrt, S Rauber, S Uebe, M Luber, A Soare, A Ekici, S Weber, AE Matei, CW Chen, C Maier, E Karouzakis, HP Kiener, E Pachera, C Dees, C Beyer, C Daniel, K Gelse, AE Kremer, E Naschberge, M Stürzl, F Butter, M Sticherlin, S Finotto, A Kreuter, MH Kaplan, A Jüngel, S Gay, SL Nutt, DW Boykin, GMK Poon, O Distler, G Schett, JHW Distler, A Ramming
    Nature, 2019-01-30;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  391. Tumour pH and protein concentration contribute to the signal of amide proton transfer magnetic resonance imaging
    Authors: KJ Ray, MA Simard, JR Larkin, J Coates, P Kinchesh, SC Smart, GS Higgins, M Chappell, N Sibson
    Cancer Res., 2019-01-24;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  392. VCAM-1–targeted MRI Enables Detection of Brain Micrometastases from Different Primary Tumors
    Authors: Vinton W.T. Cheng, Manuel Sarmiento Soto, Alexandre A. Khrapitchev, Francisco Perez-Balderas, Rasheed Zakaria, Michael D. Jenkinson et al.
    Clinical Cancer Research
  393. Identification of ILK as a critical regulator of VEGFR 3 signalling and lymphatic vascular growth
    Authors: Sofia Urner, Lara Planas‐Paz, Laura Sophie Hilger, Carina Henning, Anna Branopolski, Molly Kelly‐Goss et al.
    The EMBO Journal
  394. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA
    Authors: MA Scavuzzo, J Chmielowie, D Yang, K Wamble, LS Chaboub, L Duraine, B Tepe, SM Glasgow, BR Arenkiel, C Brou, B Deneen, M Borowiak
    Cell Rep, 2018-12-26;25(13):3811-3827.e7.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Ifs
  395. Spatially structured cell populations process multiple sensory signals in parallel in intact vascular endothelium
    Authors: Matthew D. Lee, Calum Wilson, Christopher D. Saunter, Charles Kennedy, John M. Girkin, John G. McCarron
    Science Signaling
  396. Cardiac Sca-1 + Cells Are Not Intrinsic Stem Cells for Myocardial Development, Renewal, and Repair
    Authors: Lu Zhang, Nishat Sultana, Jianyun Yan, Fan Yang, Fuxue Chen, Elena Chepurko et al.
    Circulation
  397. Semaphorin-3A protects against neointimal hyperplasia after vascular injury
    Authors: JH Wu, YF Zhou, CD Hong, AQ Chen, Y Luo, L Mao, YP Xia, QW He, HJ Jin, M Huang, YN Li, B Hu
    EBioMedicine, 2018-12-19;39(0):95-108.
    Species: Mouse
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, IHC
  398. SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells
    Authors: H Chagraoui, MS Kristianse, JP Ruiz, A Serra-Barr, J Richter, E Hall-Ponse, N Gray, D Waithe, K Clark, P Hublitz, E Repapi, G Otto, P Sopp, S Taylor, S Thongjuea, P Vyas, C Porcher
    Nat Commun, 2018-12-18;9(1):5375.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  399. An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo
    Authors: Bohong Cen, Yuanyi Wei, Wen Huang, Muzhou Teng, Shuai He, Jianlong Li et al.
    Molecular Therapy - Nucleic Acids
  400. Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization
    Authors: SH Choi, AR Kim, JK Nam, JM Kim, JY Kim, HR Seo, HJ Lee, J Cho, YJ Lee
    Nat Commun, 2018-11-30;9(1):5108.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  401. Prolonged systemic hyperglycemia does not cause pericyte loss and permeability at the mouse blood-brain barrier
    Authors: MA Mäe, T Li, G Bertuzzi, E Raschperge, M Vanlandewi, L He, K Nahar, A Dalheim, JJ Hofmann, B Laviña, A Keller, C Betsholtz, G Genové
    Sci Rep, 2018-11-29;8(1):17462.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  402. Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration
    Authors: MJ Carr, JS Toma, APW Johnston, PE Steadman, SA Yuzwa, N Mahmud, PW Frankland, DR Kaplan, FD Miller
    Cell Stem Cell, 2018-11-29;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  403. Wnt/?-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling
    Authors: K Hübner, P Cabochette, R Diéguez-Hu, C Wiesner, Y Wakayama, KS Grassme, M Hubert, S Guenther, HG Belting, M Affolter, RH Adams, B Vanhollebe, W Herzog
    Nat Commun, 2018-11-19;9(1):4860.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  404. Radiation-induced premature cellular senescence involved in glomerular diseases in rats
    Authors: S Aratani, M Tagawa, S Nagasaka, Y Sakai, A Shimizu, S Tsuruoka
    Sci Rep, 2018-11-14;8(1):16812.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  405. Genetic dissection of the miR-200-Zeb1 axis reveals its importance in tumor differentiation and invasion
    Authors: AC Title, SJ Hong, ND Pires, L Hasenöhrl, S Godbersen, N Stokar-Reg, DP Bartel, M Stoffel
    Nat Commun, 2018-11-07;9(1):4671.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  406. Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice
    Authors: Jessica Buck, James R. Larkin, Manon A. Simard, Alexandre A. Khrapitchev, Michael A. Chappell, Nicola R. Sibson
    Contrast Media & Molecular Imaging
  407. VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis
    Authors: Nicholas Beazley-Long, Catherine Elizabeth Hodge, William Robert Ashby, Samuel Marcus Bestall, Fatimah Almahasneh, Alexandra Margaret Durrant et al.
    Brain, Behavior, and Immunity
  408. Peripheral myeloid cells contribute to brain injury in male neonatal mice
    Authors: PLP Smith, A Mottahedin, P Svedin, CJ Mohn, H Hagberg, J Ek, C Mallard
    J Neuroinflammation, 2018-10-30;15(1):301.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  409. Cofilin-actin rod formation in neuronal processes after brain ischemia
    Authors: Seok Joon Won, Angela M. Minnella, Long Wu, Claire H. Eun, Eric Rome, Paco S. Herson et al.
    PLOS ONE
  410. Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells
    Authors: OA Stone, M El-Brolosy, K Wilhelm, X Liu, AM Romão, E Grillo, JKH Lai, S Günther, S Jeratsch, C Kuenne, IC Lee, T Braun, MM Santoro, JW Locasale, M Potente, DYR Stainier
    Nat Commun, 2018-10-09;9(1):4077.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  411. Endothelial repair is dependent on CD11c+ leukocytes to establish regrowing endothelial sheets with high cellular density
    Authors: U Yrlid, M Holm, M Levin, S Alsén, M Lindbom, L Glise, N Bergh, J Borén, P Fogelstran
    J. Leukoc. Biol., 2018-09-28;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  412. Angiopoietin/Tie2 axis regulates the age-at-injury cerebrovascular response to traumatic brain injury
    Authors: TR Brickler, A Hazy, F Guilhaume, R Dai, EJA Kowalski, R Dickerson, J Chen, X Wang, PD Morton, A Whittingto, A Ahmed, MH Theus
    J. Neurosci., 2018-09-21;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  413. Pentoxifylline decreases post-operative intra-abdominal adhesion formation in an animal model
    Authors: YL Yang, MG Lee, CC Lee, PI Su, CY Chi, CH Liu, MC Wu, ZS Yen, SC Chen
    PeerJ, 2018-08-24;6(0):e5434.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  414. The tyrosine phosphatase SHP2 controls TGF?-induced STAT3 signaling to regulate fibroblast activation and fibrosis
    Authors: A Zehender, J Huang, AH Györfi, AE Matei, T Trinh-Minh, X Xu, YN Li, CW Chen, J Lin, C Dees, C Beyer, K Gelse, ZY Zhang, C Bergmann, A Ramming, W Birchmeier, O Distler, G Schett, JHW Distler
    Nat Commun, 2018-08-14;9(1):3259.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  415. Mesenchymal stem cells ameliorate hyperglycemia-induced endothelial injury through modulation of mitophagy
    Authors: W Zhu, Y Yuan, G Liao, L Li, J Liu, Y Chen, J Zhang, J Cheng, Y Lu
    Cell Death Dis, 2018-08-06;9(8):837.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Flow Cytometry, IHC
  416. Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs
    Authors: Raffaella Bonavita, Kathleen Vincent, Robert Pinelli, Chitra Lekha Dahia
    Biology Open
  417. Growth Differentiation Factor 11 Promotes Neurovascular Recovery After Stroke in Mice
    Authors: Lu Lu, Xiaofei Bai, Yongliang Cao, Haiyu Luo, Xing Yang, Lijing Kang et al.
    Frontiers in Cellular Neuroscience
  418. Characterization of multi-cellular dynamics of angiogenesis and vascular remodelling by intravital imaging of the wounded mouse cornea
    Authors: Y Wang, Y Jin, B Laviña, L Jakobsson
    Sci Rep, 2018-07-13;8(1):10672.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  419. KSHV-induced ligand mediated activation of PDGF receptor-alpha drives Kaposi's sarcomagenesis
    Authors: LE Cavallin, Q Ma, J Naipauer, S Gupta, M Kurian, P Locatelli, P Romanelli, M Nadji, PJ Goldschmid, EA Mesri
    PLoS Pathog., 2018-07-09;14(7):e1007175.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  420. Syndecan-1 induction in lung microenvironment supports the establishment of breast tumor metastases
    Authors: C Chute, X Yang, K Meyer, N Yang, K O'Neil, I Kasza, K Eliceiri, C Alexander, A Friedl
    Breast Cancer Res., 2018-07-05;20(1):66.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  421. Local Arrangement of Fibronectin by Myofibroblasts Governs Peripheral Nuclear Positioning in Muscle Cells
    Authors: William Roman, João P. Martins, Edgar R. Gomes
    Developmental Cell
  422. The beta 3‐integrin endothelial adhesome regulates microtubule‐dependent cell migration
    Authors: Samuel J Atkinson, Aleksander M Gontarczyk, Abdullah AA Alghamdi, Tim S Ellison, Robert T Johnson, Wesley J Fowler et al.
    EMBO reports
  423. Bones in human CYP26B1 deficiency and rats with hypervitaminosis A phenocopy Vegfa overexpression
    Authors: T Lind, R Lugano, AM Gustafson, M Norgård, A van Haerin, A Dimberg, H Melhus, SP Robertson, G Andersson
    Bone Rep, 2018-06-21;9(0):27-36.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  424. Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy
    Authors: IS Zaitoun, U Cikla, D Zafer, E Udho, R Almomani, A Suscha, P Cengiz, CM Sorenson, N Sheibani
    Sci Rep, 2018-06-15;0(1):9166.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  425. cxcl12-engineered endothelial progenitor cells enhance neurogenesis and angiogenesis after ischemic brain injury in mice
    Authors: Y Li, S Chang, W Li, G Tang, Y Ma, Y Liu, F Yuan, Z Zhang, GY Yang, Y Wang
    Stem Cell Res Ther, 2018-05-11;9(1):139.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  426. UHRF1 epigenetically orchestrates smooth muscle cell plasticity in arterial disease
    Authors: L Elia, P Kunderfran, P Carullo, M Vacchiano, FM Farina, IF Hall, S Mantero, C Panico, R Papait, G Condorelli, M Quintavall
    J. Clin. Invest., 2018-05-07;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  427. Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice
    Authors: Z Cheng, L Wang, M Qu, H Liang, W Li, Y Li, L Deng, Z Zhang, GY Yang
    J Neuroinflammation, 2018-05-03;15(1):135.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  428. Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model
    Authors: CR Carvalho, S Wrobel, C Meyer, C Brandenber, IF Cengiz, R López-Cebr, J Silva-Corr, G Ronchi, RL Reis, C Grothe, JM Oliveira, K Haastert-T
    Biomater Sci, 2018-05-01;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  429. Nephronectin Regulates Mesangial Cell Adhesion and Behavior in Glomeruli
    Authors: Susan E. Zimmerman, Chitkale Hiremath, Jun Tsunezumi, Zhufeng Yang, Bronwyn Finney, Denise K. Marciano
    Journal of the American Society of Nephrology
  430. Positive-feedback regulation of subchondral H-type vessel formation by chondrocyte promotes osteoarthritis development in mice
    Authors: J Lu, H Zhang, D Cai, C Zeng, P Lai, Y Shao, H Fang, D Li, J Ouyang, C Zhao, D Xie, B Huang, J Yang, Y Jiang, X Bai
    J. Bone Miner. Res., 2018-03-24;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  431. Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal
    Authors: SS Rayagiri, D Ranaldi, A Raven, NIF Mohamad Az, O Lefebvre, PS Zammit, AG Borycki
    Nat Commun, 2018-03-14;9(1):1075.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  432. A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease
    Authors: X Wang, VM Philip, G Ananda, CC White, A Malhotra, PJ Michalski, KRM Karuturi, SR Chintalapu, C Acklin, M Sasner, DA Bennett, PL De Jager, GR Howell, GW Carter
    Genetics, 2018-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  433. Intratumoral administration of IL2- and TNF-based fusion proteins cures cancer without establishing protective immunity
    Authors: B Ziffels, F Pretto, D Neri
    Immunotherapy, 2018-03-01;10(3):177-188.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  434. Local delivery of tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal cells and creates an anti-inflammatory and angiogenic environment in aging mice
    Authors: B Gao, X Lin, H Jing, J Fan, C Ji, Q Jie, C Zheng, D Wang, X Xu, Y Hu, W Lu, Z Luo, L Yang
    Aging Cell, 2018-02-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  435. Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning
    Authors: Takahiro Seki, Kayoko Hosaka, Carina Fischer, Sharon Lim, Patrik Andersson, Mitsuhiko Abe et al.
    Journal of Experimental Medicine
  436. YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development
    Authors: Filipa Neto, Alexandra Klaus-Bergmann, Yu Ting Ong, Silvanus Alt, Anne-Clémence Vion, Anna Szymborska et al.
    eLife
  437. Hindlimb Ischemia Impairs Endothelial Recovery and Increases Neointimal Proliferation in the Carotid Artery
    Authors: S Sorrentino, C Iaconetti, S De Rosa, A Polimeni, J Sabatino, C Gareri, F Passafaro, T Mancuso, L Tammè, C Mignogna, C Camastra, G Esposito, A Curcio, D Torella, C Indolfi
    Sci Rep, 2018-01-15;8(1):761.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  438. Type I interferons instigate fetal demise after Zika virus infection
    Authors: LJ Yockey, KA Jurado, N Arora, A Millet, T Rakib, KM Milano, AK Hastings, E Fikrig, Y Kong, TL Horvath, S Weatherbee, HJ Kliman, CB Coyne, A Iwasaki
    Sci Immunol, 2018-01-05;3(19):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  439. Dosimetric evaluation of radionuclides for VCAM-1-targeted radionuclide therapy of early brain metastases
    Authors: N Falzone, NL Ackerman, LF Rosales, MA Bernal, X Liu, SG Peeters, MS Soto, A Corroyer-D, M Bernaudin, E Grimoin, O Touzani, NR Sibson, KA Vallis
    Theranostics, 2018-01-01;8(1):292-303.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  440. Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula
    Authors: Adriana M. Rodriguez, Karen M. Downs
    Developmental Biology
  441. Multicolor quantitative confocal imaging cytometry
    Authors: DL Coutu, KD Kokkaliari, L Kunz, T Schroeder
    Nat. Methods, 2017-11-13;15(1):39-46.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  442. Differential role of Interleukin-1 and Interleukin-6 in K-Ras-driven pancreatic carcinoma undergoing mesenchymal transition
    Authors: I Siddiqui, M Erreni, MA Kamal, C Porta, F Marchesi, S Pesce, F Pasqualini, S Schiarea, C Chiabrando, A Mantovani, P Allavena
    Oncoimmunology, 2017-11-01;7(2):e1388485.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Pr
  443. Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke
    Authors: Enming Joseph Su, Chunzhang Cao, Linda Fredriksson, Ingrid Nilsson, Christina Stefanitsch, Tamara K. Stevenson et al.
    Acta Neuropathologica
  444. PEDF expression affects retinal endothelial cell proangiogenic properties through alterations in cell adhesive mechanisms
    Authors: Juliana Falero-Perez, SunYoung Park, Christine M. Sorenson, Nader Sheibani
    American Journal of Physiology-Cell Physiology
  445. Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity
    Authors: Yixin Wang, Yi Jin, Maarja Andaloussi Mäe, Yang Zhang, Henrik Ortsäter, Christer Betsholtz et al.
    Development
  446. Natural compound bavachalcone promotes the differentiation of endothelial progenitor cells and neovascularization through the ROR?-erythropoietin-AMPK axis
    Authors: S Ling, RZ Ni, Y Yuan, YQ Dang, QM Zhou, S Liang, F Guo, W Feng, Y Chen, K Ikeda, Y Yamori, JW Xu
    Oncotarget, 2017-09-16;8(49):86188-86205.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  447. Anti-angiogenic effect of arsenic trioxide in lung cancer via inhibition of endothelial cell migration, proliferation and tube formation
    Authors: Meng-Hang Yang, Ke-Jie Chang, Jin-Cheng Zheng, Hai Huang, Guang-Yuan Sun, Xue-Wei Zhao et al.
    Oncology Letters
  448. Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents
    Authors: M Chen, X Lei, C Shi, M Huang, X Li, B Wu, Z Li, W Han, B Du, J Hu, Q Nie, W Mai, N Ma, N Xu, X Zhang, C Fan, A Hong, M Xia, L Luo, A Ma, H Li, Q Yu, H Chen, D Zhang, W Ye
    J. Clin. Invest., 2017-08-28;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  449. Resident Arterial Cells and Circulating Bone Marrow-Derived Cells both Contribute to Intimal Hyperplasia in a Rat Allograft Carotid Transplantation Model
    Authors: Y He, X Xu, T Zhu, M Tang, J Mei, Y Si
    Cell. Physiol. Biochem., 2017-07-11;42(4):1303-1312.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  450. Coronary angiogenic effect of long-term administration of Nigella sativa
    Authors: LI Al Asoom
    BMC Complement Altern Med, 2017-06-13;17(1):308.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  451. Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice
    Authors: M Aoyagi-Sch, D Crippen-Ha, R Lawrence, J Vincelette, G Yogalingam, H Prill, BK Yip, B Baridon, C Vitelli, A Lee, O Gorostiza, EG Adintori, WC Minto, JL Van Vleet, B Yates, S Rigney, TM Christians, PMN Tiger, MJ Lo, J Holtzinger, PA Fitzpatric, JH LeBowitz, S Bullens, BE Crawford, S Bunting
    Mol Ther Methods Clin Dev, 2017-06-06;6(0):43-53.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  452. Different distributions of M1 and M2 macrophages in a mouse model of laser-induced choroidal neovascularization
    Authors: Yedi Zhou, Shigeo Yoshida, Yuki Kubo, Takeru Yoshimura, Yoshiyuki Kobayashi, Takahito Nakama et al.
    Molecular Medicine Reports
  453. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling
    Authors: Y Jin, L Muhl, M Burmakin, Y Wang, AC Duchez, C Betsholtz, HM Arthur, L Jakobsson
    Nat. Cell Biol., 2017-05-22;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  454. Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues
    Authors: WW Sugden, R Meissner, T Aegerter-W, R Tsaryk, EV Leonard, J Bussmann, MJ Hamm, W Herzog, Y Jin, L Jakobsson, C Denz, AF Siekmann
    Nat. Cell Biol., 2017-05-22;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  455. Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development
    Authors: K Gerl, D Steppan, M Fuchs, C Wagner, C Willam, A Kurtz, B Kurt
    Am. J. Pathol., 2017-05-17;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  456. Immunofluorescence reveals unusual patterns of labelling for connexin43 localized to calbindin-D28K-positive interstitial cells in the pineal gland
    Authors: DD Tsao, SG Wang, BD Lynn, JI Nagy
    Eur. J. Neurosci., 2017-05-11;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  457. Gli1(+) Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target
    Authors: RK Schneider, A Mullally, A Dugourd, F Peisker, R Hoogenboez, PMH Van Strien, EM Bindels, D Heckl, G Büsche, D Fleck, G Müller-New, J Wongboonsi, M Ventura Fe, VG Puelles, J Saez-Rodri, BL Ebert, BD Humphreys, R Kramann
    Cell Stem Cell, 2017-04-27;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  458. Excessive dietary intake of vitamin A reduces skull bone thickness in mice
    Authors: T Lind, C Öhman, G Calounova, A Rasmusson, G Andersson, G Pejler, H Melhus
    PLoS ONE, 2017-04-20;12(4):e0176217.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-P
  459. Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula
    Authors: AM Rodriguez, DX Jin, AD Wolfe, MM Mikedis, L Wierenga, MP Hashmi, C Viebahn, KM Downs
    Dev. Biol., 2017-04-04;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  460. Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy
    Authors: N Yang, W Zhang, T He, Y Xing
    Exp. Eye Res, 2017-02-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  461. Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome
    Authors: S Nakamura, H Osaka, SI Muramatsu, N Takino, M Ito, S Aoki, EF Jimbo, K Shimazaki, T Onaka, S Ohtsuki, T Terasaki, T Yamagata
    Mol Genet Metab Rep, 2017-01-15;10(0):67-74.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  462. Impacts of femoral artery and vein excision versus femoral artery excision on the hindlimb ischemic model in CD-1 mice
    Authors: Miao Chen
    Microvasc. Res, 2016-12-18;110(0):48-55.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  463. Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells
    J Leukoc Biol, 2016-08-04;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  464. TLR2-mediated leukocyte trafficking to the developing brain
    J Leukoc Biol, 2016-08-04;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  465. Different cyclical intermittent hypoxia severities have different effects on hippocampal microvasculature
    Authors: Diane C. Lim, Daniel C. Brady, Rajath Soans, Emily Y. Kim, Laise Valverde, Brendan T. Keenan et al.
    Journal of Applied Physiology
  466. Osteogenic potential of alpha smooth muscle actin expressing muscle resident progenitor cells
    Authors: Brya G. Matthews, Elena Torreggiani, Emilie Roeder, Igor Matic, Danka Grcevic, Ivo Kalajzic
    Bone
  467. Ng BR is essential for endothelial cell glycosylation and vascular development
    Authors: Eon Joo Park, Kariona A Grabińska, Ziqiang Guan, William C Sessa
    EMBO reports
  468. Vascular Defects and Spinal Cord Hypoxia in Spinal Muscular Atrophy
    Authors: Eilidh Somers, Robert D. Lees, Katie Hoban, James N. Sleigh, Haiyan Zhou, Francesco Muntoni et al.
    Annals of Neurology
  469. FOXO1 couples metabolic activity and growth state in the vascular endothelium
    Authors: Kerstin Wilhelm, Katharina Happel, Guy Eelen, Sandra Schoors, Mark F. Oellerich, Radiance Lim et al.
    Nature
  470. Integrin beta1 controls VE-cadherin localization and blood vessel stability.
    Authors: Yamamoto H, Ehling M, Kato K, Kanai K, van Lessen M, Frye M, Zeuschner D, Nakayama M, Vestweber D, Adams R
    Nat Commun, 2015-03-10;6(0):6429.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  471. The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.
    Authors: Shi X, Zirbes K, Rasmussen T, Ferdous A, Garry M, Koyano-Nakagawa N, Garry D
    J Biol Chem, 2015-02-18;290(15):9614-25.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  472. Connective Tissue Growth Factor reporter mice label a subpopulation of mesenchymal progenitor cells that reside in the trabecular bone region
    Authors: Wen Wang, Sara Strecker, Yaling Liu, Liping Wang, Fayekah Assanah, Spenser Smith et al.
    Bone
  473. Formation of fenestrae in murine liver sinusoids depends on plasmalemma vesicle-associated protein and is required for lipoprotein passage.
    Authors: Herrnberger, Leonie, Hennig, Robert, Kremer, Werner, Hellerbrand, Claus, Goepferich, Achim, Kalbitzer, Hans Rob, Tamm, Ernst R
    PLoS ONE, 2014-12-26;9(12):e115005.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  474. Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking alpha V beta 8-TGF beta signaling in the brain
    Authors: Thomas D. Arnold, Colin Niaudet, Mei-Fong Pang, Julie Siegenthaler, Konstantin Gaengel, Bongnam Jung et al.
    Development
  475. The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
    Authors: Prevete N, Liotti F, Visciano C, Marone G, Melillo R, de Paulis A
    Oncogene, 2014-09-29;34(29):3826-38.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  476. Peroxisome proliferator-activated receptor alpha protects capillary pericytes in the retina.
    Authors: Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins A, Keech A, Humphries K, Gu X, Elliott M, Xia X, Ma J
    Am J Pathol, 2014-08-07;184(10):2709-20.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  477. Periadventitial application of rapamycin-loaded nanoparticles produces sustained inhibition of vascular restenosis.
    Authors: Shi, Xudong, Chen, Guojun, Guo, Lian-Wan, Si, Yi, Zhu, Men, Pilla, Srikanth, Liu, Bo, Gong, Shaoqin, Kent, K Craig
    PLoS ONE, 2014-02-21;9(2):e89227.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  478. Anticancer effects of gemcitabine are enhanced by co-administered iRGD peptide in murine pancreatic cancer models that overexpressed neuropilin-1.
    Authors: Akashi Y, Oda T, Ohara Y, Miyamoto R, Kurokawa T, Hashimoto S, Enomoto T, Yamada K, Satake M, Ohkohchi N
    Br J Cancer, 2014-02-20;110(6):1481-7.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  479. ITE and TCDD differentially regulate the vascular remodeling of rat placenta via the activation of AhR.
    Authors: Wu Y, Chen X, Zhou Q, He Q, Kang J, Zheng J, Wang K, Duan T
    PLoS ONE, 2014-01-24;9(1):e86549.
    Species: Mouse, Rat
    Sample Types: Whole Tissue
    Applications: IHC, IHC-P
  480. Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies.
    Authors: Holloway, A C, Salomon, A, Soares, M J, Garnier, V, Raha, S, Sergent, F, Nicholson, C J, Feige, J J, Benharouga, M, Alfaidy, N
    Am J Physiol Endocrinol Metab, 2013-12-24;306(4):E443-56.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  481. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
    Authors: Adini, Irit, Ghosh, Kaustabh, Adini, Avner, Chi, Zai-Long, Yoshimura, Takeru, Benny, Ofra, Connor, Kip M, Rogers, Michael, Bazinet, Lauren, Birsner, Amy E, Bielenberg, Diane R, D'Amato, Robert J
    J Clin Invest, 2013-12-20;124(1):425-36.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  482. MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain.
    Authors: Zeng, L, He, X, Wang, Y, Tang, Y, Zheng, C, Cai, H, Liu, J, Wang, Y, Fu, Y, Yang, G-Y
    Gene Ther, 2013-10-24;21(1):37-43.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  483. The nucleus of endothelial cell as a sensor of blood flow direction
    Authors: Eugene Tkachenko, Edgar Gutierrez, Semion K. Saikin, Per Fogelstrand, Chungho Kim, Alex Groisman et al.
    Biology Open
  484. Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-beta signaling pathways.
    Authors: Park S, Dimaio T, Liu W, Wang S, Sorenson C, Sheibani N
    J Cell Sci, 2013-02-15;126(0):1392-405.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  485. TGF-beta mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.
    Authors: Shinojima N, Hossain A, Takezaki T, Fueyo J, Gumin J, Gao F, Nwajei F, Marini F, Andreeff M, Kuratsu J, Lang F
    Cancer Res, 2013-01-30;73(7):2333-44.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  486. The identification of different endothelial cell populations within the mouse proepicardium
    Authors: Stephanie Cossette, Ravi Misra
    Developmental Dynamics
  487. The critical role of agrin in the hematopoietic stem cell niche.
    Authors: Mazzon C, Anselmo A, Cibella J, Soldani C, Destro A, Kim N, Roncalli M, Burden SJ, Dustin ML, Sarukhan A, Viola A
    Blood, 2011-06-07;118(10):2733-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  488. Dysfunctional microvasculature as a consequence of shb gene inactivation causes impaired tumor growth.
    Authors: Funa NS, Kriz V, Zang G, Calounova G, Akerblom B, Mares J, Larsson E, Sun Y, Betsholtz C, Welsh M
    Cancer Res., 2009-02-17;69(5):2141-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  489. Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin.
    Authors: Rebholz B, Haase I, Eckelt B, Paxian S, Flaig MJ, Ghoreschi K, Nedospasov SA, Mailhammer R, Debey-Pascher S, Schultze JL, Weindl G, Forster I, Huss R, Stratis A, Ruzicka T, Rocken M, Pfeffer K, Schmid RM, Rupec RA
    Immunity, 2007-08-09;27(2):296-307.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  490. RBFOX2 is required for establishing RNA regulatory networks essential for heart development
    Authors: Verma SK, Deshmukh V, Thatcher K et al.
    Nucleic acids research
  491. An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression
    Authors: Scheidmann MC, Castro-Giner F, Strittmatter K et al.
    Cancer research
  492. The endothelial dysfunction blocker CU06-1004 ameliorates choline-deficient L-amino acid diet-induced non-alcoholic steatohepatitis in mice
    Authors: CR Bae, H Zhang, YG Kwon
    PLoS ONE, 2020-12-04;15(12):e0243497.
  493. Adaptable toolbox to characterize Alzheimer’s disease pathology in mouse models
    Authors: Youtong H, Greg L
    STAR Protocols
  494. Radiation-Induced Changes in Tumor Vessels and Microenvironment Contribute to Therapeutic Resistance in Glioblastoma
    Authors: Seo B, Jeon K, Moon S, et al.
    Front Oncol
  495. Intercrypt sentinel macrophages tune antibacterial NF-kappa B responses in gut epithelial cells via TNF
    Authors: Hausmann A, Felmy B, Kunz L et al.
    J Exp Med
  496. CNS Pericytes Modulate Local T Cell Infiltration in EAE
    Authors: K Koch, M Lindner, AK Fleck, M Liebmann, M Eschborn, L Zondler, R Diéguez-Hu, RH Adams, G Meyer Zu H, A Zarbock, T Kuhlmann, H Wiendl, L Klotz
    International Journal of Molecular Sciences, 2022-10-28;23(21):.
  497. Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis
    Authors: Lv JJ, Wang H, Cui HY, et al.
    Frontiers in cell and developmental biology
  498. Distinct tumor architectures for metastatic colonization of the brain
    Authors: S Gan, DG Macalinao, SH Shahoei, L Tian, X Jin, H Basnet, JT Muller, P Atri, E Seffar, W Chatila, AK Hadjantona, N Schultz, E Brogi, TA Bale, D Pe'er, J Massagué
    bioRxiv : the preprint server for biology, 2023-01-28;0(0):.
  499. YAP1 and TAZ negatively control bone angiogenesis by limiting hypoxia-inducible factor signaling in endothelial cells
    Authors: Sivaraj KK, Dharmalingam B, Mohanakrishnan V et al.
    Elife
  500. Isolation Methods for Human CD34 Subsets Using Fluorescent and Magnetic Activated Cell Sorting: an In Vivo Comparative Study
    Authors: Tripathi H, Peng H, Donahue R et al.
    Stem Cell Rev Rep
  501. RIPK3 modulates growth factor receptor expression in endothelial cells to support angiogenesis
    Authors: Gao S, Griffin CT
    Angiogenesis
  502. A Type 2 Deiodinase-Dependent Increase in Vegfa Mediates Myoblast-Endothelial Cell Crosstalk During Skeletal Muscle Regeneration
    Authors: Xingxing An, Ashley Ogawa-Wong, Colleen Carmody, Raffaele Ambrosio, Annunziata Gaetana Cicatiello, Cristina Luongo et al.
    Thyroid
  503. Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model
    Authors: Gabrusiewicz K, Hossain MB, Cortes-Santiago N et al.
    Neoplasia

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Reviews for Human/Mouse/Rat CD31/PECAM-1 Antibody

Average Rating: 4.9 (Based on 19 Reviews)

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Human/Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 08/08/2024
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Human lung tissue Species: Human
Immunocytochemistry/Immunofluorescence Human/Mouse/Rat CD31/PECAM-1 Antibody AF3628
Human/Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 08/08/2024
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Primary Mouse endothelial cells Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse/Rat CD31/PECAM-1 Antibody AF3628
Human/Mouse/Rat CD31/PECAM-1 Antibody
By Sergio Barrios on 09/15/2023
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Lung tissue Species: Mouse

Mouse lungs stained with DAPI (Cyan) and CD31 AF3628 (Red) at 1:200 dilution of primary and secondary antibodies.

Immunocytochemistry/Immunofluorescence Human/Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 09/14/2022
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Liver tissue Species: Mouse

PLP fixed 12 μm cryosection of mouse liver was stained 1:200 (from a stock of 0.2 mg/ml) overnight at room temperature (and with an antibody against Clec4f), followed by Donkey anti-goat CF488A @ 1:500 for 1h @ room temperature. Great staining of liver endothelium.

Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 08/18/2022
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adult pancreas Species: Mouse

Adult pancreas cryostat sections stained with goat anti-CD31 and a donkey anti-goat AF488 (in green) as well as a directly conjugated rat anti-CD45-BV421 antibody (in blue). The CD31 staining works very well, clearly labelling pancreatic endothelium.

Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 02/05/2022
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Lung cancer tissue,Lung tissue Species: Mouse

This antibody is good and easy to use!

Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By MASNSEN CHERIEF on 12/20/2021
Application: Staining Sample Tested: ulna Species: Mouse
Other Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 11/30/2021
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adipose tissue Species: Mouse
Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 12/09/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Brown adipose tissue Species: Mouse

Detection of CD31/PECAM‑1 in Mouse brown adipose tissue. 4% PFA fixed Brown adipose tissue was embedded in OCT and cryosectioned at 10µm. After permeabilization and blocking, tissue was incubated overnight at 4˚C with 2µg/ml of gt@CD31 (AF3628) and detected with Alexa fluor dk@gt 488 (1:1000) the next day. CD31 is presented in pseudo color violet here. This product is great, always very clear and bright. I often use it with 488 channel in tissues with strong autofluorescence such as hearts and quadriceps.

Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 12/08/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: E12.5 mouse embryo fixed in 4% PFA Species: Mouse

One of the best antibodies.
Used on E9.5-E12.5 cryo embedded mouse embryo sections (4% PFA fixed).
Attached picture is E12.5 embryo section.
Dilution used - 1:200

Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 11/20/2020
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adult brain Species: Mouse
Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Vanessa Santos on 01/21/2020
Application: IHC Sample Tested: Brain (cortex) tissue,Brain (hippocampus) Species: Rat
Immunohistochemistry Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 08/20/2018
Application: IHC Sample Tested: Liver tissue Species: Rat

FFPE rat liver stained using AF3628 at 15 µg/mL overnight at 4C. Epitope retrieval was performed at 95 C for 15 minutes in citrate buffer pH 6.0. Secondary was donkey anti-goat Alexa Fluor 555 (psuedocolored red).

Immunohistochemistry Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By yijun su on 06/02/2018
Application: CLARITY deep tissue imaging Sample Tested: Adult kidney Species: Mouse

Optically cleared 1 mm mouse kidney section
Imaged by diSPIM in 60% TDE with 17X lens

Secondary antibody is donkey anti goat alexa 488

Red is Tubulin Beta 3 stained by alexa 568

Other Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 04/05/2018
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Adult brain Species: Mouse

Excellent!

Immunocytochemistry/Immunofluorescence Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Peter Caradonna on 03/26/2018
Application: IHC Sample Tested: Liver tissue Species: Mouse

FFPE mouse liver stained O/N at 4C with AF3826 at 10 ug/mL in 0.3% PBS-Tx. Secondary Donkey anti-goat Alexa Fluor 488 was applied for 1 hr RT at 2 ug/mL in PBS-Tx. Citrate buffer pH 6.0 used for epitope retrieval.

Immunohistochemistry Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 09/12/2017
Application: IHC Sample Tested: Embryonic kidney Species: Mouse
Immunohistochemistry Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Anonymous on 06/29/2017
Application: IHC Sample Tested: Formalin Fixed Paraffin Embedded Mouse Liver Species: Mouse

WD [1:500], HIER with DIVA; secondary ab RTU Polymer-HRP

Immunohistochemistry Mouse/Rat CD31/PECAM-1 Antibody AF3628
Mouse/Rat CD31/PECAM-1 Antibody
By Zhiheng He on 08/08/2016
Application: IHC Sample Tested: Embryo tissue Species: Mouse

E9.5 mouse embryonic tissue, whole mount staining with 1:100 dilution, Alex Fluor 594 donkey anti-goat with 1:400 dilution.

Immunohistochemistry Mouse/Rat CD31/PECAM-1 Antibody AF3628