Mouse VEGF Quantikine ELISA Kit Summary
Product Summary
Precision
Cell Culture Supernates, Tissue Homogenates, Serum, EDTA Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean (pg/mL) | 37.7 | 144 | 277 | 38.3 | 138 | 291 |
Standard Deviation | 3.1 | 6.2 | 12.9 | 3.2 | 7.8 | 18.5 |
CV% | 8.2 | 4.3 | 4.7 | 8.4 | 5.7 | 6.4 |
Recovery
The recovery of mouse VEGF spiked to three levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Supernates (n=9) | 103 | 95-114 |
EDTA Plasma (n=5) | 91 | 82-103 |
Heparin Plasma (n=4) | 89 | 87-94 |
Serum (n=9) | 101 | 83-115 |
Tissue Homogenates (n=3) | 91 | 76-107 |
Linearity
Scientific Data
Mouse VEGF Quantikine ELISA Kit Increased production of proinflammatory cytokines and VEGF in the plasma and chondrocytes in high fat diet (HFD)-feeding mice.(a~d) levels of plasma IL-6 (a), TNF-alpha (b), IL-1 beta (c) and VEGF (d) in the C57BL/6 male mice fed with a normal diet (ND) or HFD for 8 weeks. (n = 5, **P < 0.01). (e~h) Relative mRNA expression of IL-6 (e), TNF-alpha (f), IL-1 beta (g) and VEGF (h) in the chondrocytes isolated from the 8-week ND or HFD-feeding mice. (n = 5, **P < 0.01). Image collected and cropped by CiteAb from the following open publication (https://pubmed.ncbi.nlm.nih.gov/26271607), licensed under a CC-BY license. Not internally tested by R&D Systems.
Product Datasheets
Preparation and Storage
Background: VEGF
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and in adults (1-3). It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues in a cystine knot structure and the formation of anti-parallel disulfide-linked dimers (4). Alternately spliced isoforms of 120, 164 and 188 amino acids (aa) have been found in mice, while 121, 145, 165, 183, 189, and 206 aa isoforms have been identified in humans (2, 4). In humans, VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189 (3, 4). The same pattern may exist in mice. Isoforms other than VEGF120 and VEGF121 contain basic heparin-binding regions and are not freely diffusible (4). Mouse VEGF164 shares 97% aa sequence identity with corresponding regions of rat VEGF. It also shares 89% aa sequence identity with human and porcine VEGF, 88% with bovine VEGF, and 90% with feline, equine, and canine VEGF. VEGF is expressed in multiple cells and tissues including skeletal and cardiac muscle (5, 6), hepatocytes (7), osteoblasts (8), neutrophils (9), macrophages (10), keratinocytes (11), brown adipose tissue (12), CD34+ stem cells (13), endothelial cells (14), fibroblasts, and vascular smooth muscle cells (15). VEGF expression is induced by hypoxia and cytokines such as IL-1, IL-6, IL-8, Oncostatin M, and TNF-alpha (3, 4, 9, 16). The isoforms are differentially expressed during development and in the adult (3).
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 50 µL of Assay Diluent to each well.
- Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
- Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
- Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
- Aspirate and wash 5 times.
- Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Mouse VEGF Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Muti-target rationale design of novel substituted N-phenyl-2-((6-phenylpyridazin-3-yl)thio)acetamide candidates as telomerase/JAK1/STAT3/TLR4 inhibitors: In vitro and in vivo investigations
Authors: Shaldam, MA;Mousa, MHA;Tawfik, HO;El-Dessouki, AM;Sharaky, M;Saleh, MM;Alzahrani, AYA;Moussa, SB;Al-Karmalawy, AA;
Bioorganic chemistry
Species: Mouse
Sample Types: Tissue Homogenates
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Co-culture of vascular endothelial cells enhances corticosterone production in steroid hormone-producing cells generated from adipose-derived mesenchymal stromal cells
Authors: Niimi, T;Tanaka, T;Aoyagi, C;Onda, Y;Nagamitsu, S;Kodama, S;
Scientific reports
Species: Mouse
Sample Types: Cell Culture Supernates
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Targeting NGF but not VEGFR1 or BDNF signaling reduces endometriosis-associated pain in mice
Authors: Zaninelli, TH;Fattori, V;Heintz, OK;Wright, KR;Bennallack, PR;Sim, D;Bukhari, H;Terry, KL;Vitonis, AF;Missmer, SA;Andrello, AC;Anchan, RM;Godin, SK;Bree, D;Verri, WA;Rogers, MS;
Journal of advanced research
Species: Mouse, Transgenic Mouse
Sample Types: Tissue Homogenates
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Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation in Muscle
Authors: Mann, CG;MacArthur, MR;Zhang, J;Gong, S;AbuSalim, JE;Hunter, CJ;Lu, W;Agius, T;Longchamp, A;Allagnat, F;Rabinowitz, J;Mitchell, JR;De Bock, K;Mitchell, SJ;
bioRxiv : the preprint server for biology
Species: Mouse, Transgenic Mouse
Sample Types: Tissue Homogenates
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Double hits with bioactive nanozyme based on cobalt-doped nanoglass for acute and diabetic wound therapies through anti-inflammatory and pro-angiogenic functions
Authors: Mandakhbayar, N;Ji, Y;El-Fiqi, A;Patel, KD;Yoon, DS;Dashnyam, K;Bayaraa, O;Jin, G;Tsogtbaatar, K;Kim, TH;Lee, JH;Kim, HW;
Bioactive materials
Species: Human, Mouse
Sample Types: Cell Culture Supernates, Tissue Homogenates
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Hypoxia-inducible factor 1? modulates interstitial pneumonia-mediated lung cancer progression
Authors: Shimoji, K;Nakashima, T;Masuda, T;Namba, M;Sakamoto, S;Yamaguchi, K;Horimasu, Y;Mimae, T;Miyamoto, S;Iwamoto, H;Fujitaka, K;Hamada, H;Okada, M;Hattori, N;
Journal of translational medicine
Species: Mouse
Sample Types: Tissue Homogenates
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Telocyte-Derived Exosomes Provide an Important Source of Wnts That Inhibits Fibrosis and Supports Regeneration and Repair of Endometrium
Authors: Chen, TQ;Wei, XJ;Liu, HY;Zhan, SH;Yang, XJ;
Cell transplantation
Species: Mouse
Sample Types: Cell Culture Supernates
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Protective effects of macrophage-specific integrin ?5 in myocardial infarction are associated with accentuated angiogenesis
Authors: Li, R;Chen, B;Kubota, A;Hanna, A;Humeres, C;Hernandez, SC;Liu, Y;Ma, R;Tuleta, I;Huang, S;Venugopal, H;Zhu, F;Su, K;Li, J;Zhang, J;Zheng, D;Frangogiannis, NG;
Nature communications
Species: Mouse
Sample Types: Cell Culture Supernates
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Rescue of murine hind limb ischemia via angiogenesis and lymphangiogenesis promoted by cellular communication network factor 2
Authors: Shimizu, M;Yoshimatsu, G;Morita, Y;Tanaka, T;Sakata, N;Tagashira, H;Wada, H;Kodama, S;
Scientific reports
Species: Mouse
Sample Types: Tissue Homogenates
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Inhibition of CDK1 by RO-3306 Exhibits Anti-Tumorigenic Effects in Ovarian Cancer Cells and a Transgenic Mouse Model of Ovarian Cancer
Authors: Huang, Y;Fan, Y;Zhao, Z;Zhang, X;Tucker, K;Staley, A;Suo, H;Sun, W;Shen, X;Deng, B;Pierce, SR;West, L;Yin, Y;Emanuele, MJ;Zhou, C;Bae-Jump, V;
International journal of molecular sciences
Species: Mouse
Sample Types: Serum
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Increased beta2-adrenergic signaling is a targetable stimulus essential for bone healing by promoting callus neovascularization
Authors: Jahn, D;Knapstein, PR;Otto, E;Köhli, P;Sevecke, J;Graef, F;Graffmann, C;Fuchs, M;Jiang, S;Rickert, M;Erdmann, C;Appelt, J;Revend, L;Küttner, Q;Witte, J;Rahmani, A;Duda, G;Xie, W;Donat, A;Schinke, T;Ivanov, A;Tchouto, MN;Beule, D;Frosch, KH;Baranowsky, A;Tsitsilonis, S;Keller, J;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Cell Culture Supernates
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The Role of Hyperthermia in Potentiation of Anti-Angiogenic Effect of Cisplatin and Resveratrol in Mice Bearing Solid Form of Ehrlich Ascites Tumour
Authors: Kučan, D;Oršolić, N;Odeh, D;Ramić, S;Jakopović, B;Knežević, J;Jazvinšćak Jembrek, M;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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Chondroitin/Lactoferrin-dual functionalized pterostilbene-solid lipid nanoparticles as targeted breast cancer therapy
Authors: Aly, S;El-Kamel, AH;Sheta, E;El-Habashy, SE;
International journal of pharmaceutics
Species: Mouse
Sample Types: Tissue Homogenates
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Mannose-Coated Reconstituted Lipoprotein Nanoparticles for the Targeting of Tumor-Associated Macrophages: Optimization, Characterization, and In Vitro Evaluation of Effectiveness
Authors: Dossou, AS;Mantsch, ME;Kapic, A;Burnett, WL;Sabnis, N;Coffer, JL;Berg, RE;Fudala, R;Lacko, AG;
Pharmaceutics
Species: Mouse
Sample Types: Cell Culture Supernates
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Pericardial Grafting of Cardiac Progenitor Cells in Self-Assembling Peptide Scaffold Improves Cardiac Function After Myocardial Infarction
Authors: Kanda, M;Nagai, T;Kondo, N;Matsuura, K;Akazawa, H;Komuro, I;Kobayashi, Y;
Cell transplantation
Species: Mouse
Sample Types: Cell Culture Supernates
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Inhaled pan-phosphodiesterase inhibitors ameliorate ovalbumin-induced airway inflammation and remodeling in murine model of allergic asthma
Authors: W�jcik-Pszczo?a, K;Pociecha, K;Ch?o?-Rzepa, G;Zadro?na, M;Nowak, B;Plutecka, H;Koczurkiewicz-Adamczyk, P;Przejczowska-Pomierny, K;P?kala, E;Gosens, R;Wyska, E;
International immunopharmacology
Species: Mouse
Sample Types: Tissue Homogenates
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Stimulating the Melanocortin System in Uveitis and Diabetes Preserves the Structure and Anti-Inflammatory Activity of the Retina
Authors: TF Ng, AW Taylor
International Journal of Molecular Sciences, 2023-04-08;24(8):.
Species: Mouse
Sample Types: Tissue Homogenates
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CRISPR/Cas9 mediated specific ablation of vegfa in retinal pigment epithelium efficiently regresses choroidal neovascularization
Authors: J Park, G Cui, H Lee, H Jeong, JJ Kwak, J Lee, SH Byeon
Scientific Reports, 2023-03-06;13(1):3715.
Species: Mouse
Sample Types: Aqueous Humor
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HIF-1alpha accumulation in response to transient hypoglycemia may worsen diabetic eye disease
Authors: C Guo, M Deshpande, Y Niu, I Kachwala, M Flores-Bel, H Megarity, T Nuse, S Babapoor-F, M Ramada, J Sanchez, N Inamdar, TV Johnson, MV Canto-Sole, S Montaner, A Sodhi
Cell Reports, 2023-01-10;42(1):111976.
Species: Human
Sample Types: Cell Culture Supernates
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Letrozole increases preantral follicle growth and decreases estradiol production without impairing follicle survival
Authors: F Kasuga-Yam, T Baba, S Nagao, Y Fujibe, M Morishita, Y Kuno, T Mariya, H Honnma, T Endo, T Kiya, T Saito
Journal of ovarian research, 2022-12-24;15(1):136.
Species: Mouse
Sample Types: Cell Culture Supernates
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Safeguarding genome integrity during gene-editing therapy in a mouse model of age-related macular degeneration
Authors: J Yin, K Fang, Y Gao, L Ou, S Yuan, C Xin, W Wu, WW Wu, J Hong, H Yang, J Hu
Nature Communications, 2022-12-22;13(1):7867.
Species: Mouse
Sample Types: Tissue Homogenates
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VHL-recruiting PROTAC attenuates renal fibrosis and preserves renal function via simultaneous degradation of Smad3 and stabilization of HIF-2alpha
Authors: J Yang, Y Ruan, D Wang, J Fan, N Luo, H Chen, X Li, W Chen, X Wang
Cell & bioscience, 2022-12-19;12(1):203.
Species: Mouse
Sample Types: Serum
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GPR174 knockdown enhances blood flow recovery in hindlimb ischemia mice model by upregulating AREG expression
Authors: J Liu, L Pan, W Hong, S Chen, P Bai, W Luo, X Sun, F He, X Jia, J Cai, Y Chen, K Hu, Z Song, J Ge, A Sun
Nature Communications, 2022-12-06;13(1):7519.
Species: Transgenic Mouse
Sample Types: Cell Culture Supernates
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Effect of triamcinolone acetonide on retinal inflammation and angiogenesis induced by pericyte depletion in mouse
Authors: T Otsuka, T Masuda, Y Takahashi, A Suzuki, A Uemura, R Arakawa, T Okabe, A Naito
Journal of pharmacological sciences, 2022-10-23;151(1):28-36.
Species: Mouse
Sample Types: Tissue Homogenates
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A single intravenous injection of cyclosporin A-loaded lipid nanocapsules prevents retinopathy of prematurity
Authors: M Bohley, AE Dillinger, F Schweda, A Ohlmann, BM Braunger, ER Tamm, A Goepferich
Science Advances, 2022-09-23;8(38):eabo6638.
Species: Mouse
Sample Types: Tissue Lysates
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Dry preserved multilayered fibroblast cell sheets are a new manageable tool for regenerative medicine to promote wound healing
Authors: Y Matsuno, M Yanagihara, K Ueno, T Saito, H Kurazumi, R Suzuki, S Katsura, A Oga, K Hamano
Scientific Reports, 2022-07-22;12(1):12519.
Species: Mouse
Sample Types: Cell Lysates
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Association between vascular endothelial growth factor-mediated blood-brain barrier dysfunction and stress-induced depression
Authors: H Matsuno, S Tsuchimine, K O'Hashi, K Sakai, K Hattori, S Hidese, S Nakajima, S Chiba, A Yoshimura, N Fukuzato, M Kando, M Tatsumi, S Ogawa, N Ichinohe, H Kunugi, K Sohya
Molecular Psychiatry, 2022-05-26;0(0):.
Species: Mouse
Sample Types: Serum
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BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk
Authors: T Bork, W Liang, O Kretz, S Lagies, K Yamahara, C Hernando-E, M Helmstädte, C Schell, B Kammerer, TB Huber
International Journal of Molecular Sciences, 2022-03-30;23(7):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Pharmacological Inhibition of Glutaminase 1 Attenuates Alkali-Induced Corneal Neovascularization by Modulating Macrophages
Authors: Y Feng, X Yang, J Huang, M Shen, L Wang, X Chen, Y Yuan, C Dong, X Ma, F Yuan
Oxidative Medicine and Cellular Longevity, 2022-03-19;2022(0):1106313.
Species: Mouse
Sample Types: Protein
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Regenerating glomerular metabolism and function by podocyte pyruvate kinase M2 in diabetic nephropathy
Authors: J Fu, T Shinjo, Q Li, R St-Louis, K Park, MG Yu, H Yokomizo, F Simao, Q Huang, IH Wu, GL King
JCI Insight, 2022-03-08;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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AKT-AMPKalpha-mTOR-dependent HIF-1alpha Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma
Authors: EE Abd El-Fat, S Saber, ME Youssef, H Eissa, E El-Ahwany, NA Amin, M Alqarni, GE Batiha, AJ Obaidullah, MMY Kaddah, AG Ahmed Gaaf, AAE Mourad, G Mostafa-He, AM Abdelhamid
Frontiers in Pharmacology, 2022-01-12;12(0):720173.
Species: Mouse
Sample Types: Tissue Homogenates
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Resveratrol and its nanocrystals: A promising approach for cancer therapy?
Authors: D An?i?, N Oršoli?, D Odeh, M Tomaševi?, I Pepi?, S Rami?
Toxicology and Applied Pharmacology, 2021-12-29;435(0):115851.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
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High-Fat Diet-Induced Obese Effects of Adipocyte-Specific CXCR2 Conditional Knockout in the Peritoneal Tumor Microenvironment of Ovarian Cancer
Authors: D Choe, ES Lee, A Beeghly-Fa, AJ Wilson, MM Whalen, SE Adunyah, DS Son
Cancers, 2021-10-08;13(19):.
Species: Mouse
Sample Types: Tissue Homogenates
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Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches
Authors: M Mesnieres, AM Böhm, N Peredo, D Trompet, R Valle-Tenn, M Bajaj, N Corthout, E Nefyodova, R Cardoen, P Baatsen, S Munck, A Nagy, JJ Haigh, S Khurana, CM Verfaillie, C Maes
Cell Reports, 2021-08-24;36(8):109618.
Species: Mouse
Sample Types: Tissue Homogenates
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Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo
Authors: T Mashima, T Wakatsuki, N Kawata, MK Jang, A Nagamori, H Yoshida, K Nakamura, T Migita, H Seimiya, K Yamaguchi
Scientific Reports, 2021-07-23;11(1):15125.
Species: Mouse
Sample Types: Plasma
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Enhanced cellular engraftment of adipose-derived mesenchymal stem cell spheroids by using nanosheets as scaffolds
Authors: H Nagano, Y Suematsu, M Takuma, S Aoki, A Satoh, E Takayama, M Kinoshita, Y Morimoto, S Takeoka, T Fujie, T Kiyosawa
Scientific Reports, 2021-07-14;11(1):14500.
Species: Mouse
Sample Types: Tissue Homogenates
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Acid Sensing Ion Channel 2a Is Reduced in the Reduced Uterine Perfusion Pressure Mouse Model and Increases Seizure Susceptibility in Pregnant Mice
Authors: M Jones-Muha, Q Shao, L Cain-Shiel, JP Shaffery, JP Warrington
Cells, 2021-05-08;10(5):.
Species: Mouse
Sample Types: Serum
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Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI)
Authors: CK Lin, TH Huang, CT Yang, CS Shi
PLoS ONE, 2021-03-19;16(3):e0248959.
Species: Mouse
Sample Types: Cell Culture Supernates
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Agomelatine Attenuates Isoflurane-Induced Inflammation and Damage in Brain Endothelial Cells
Authors: F Cheng, H Chang, F Yan, A Yang, J Liu, Y Liu
Drug Design, Development and Therapy, 2020-12-18;14(0):5589-5598.
Species: Mouse
Sample Types: Cell Culture Supernates
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Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling
Authors: Y Xiong, MJ Scerbo, A Seelig, F Volta, N O'Brien, A Dicker, D Padula, H Lickert, JM Gerdes, PO Berggren
Elife, 2020-11-17;9(0):.
Species: Human
Sample Types: Cell Culture Supernates
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An allosteric peptide inhibitor of HIF-1&alpha regulates hypoxia-induced retinal neovascularization
Authors: A Usui-Ouchi, E Aguilar, S Murinello, M Prins, ML Gantner, PE Wright, RB Berlow, M Friedlande
Proc Natl Acad Sci U S A, 2020-10-26;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23
Authors: PL Mulcrone, SKE Edwards, DN Petrusca, LS Haneline, J Delgado-Ca, GD Roodman
Sci Rep, 2020-10-14;10(1):17319.
Species: Mouse
Sample Types: Cell Culture Supernates
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Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors
Authors: K Hosaka, Y Yang, T Seki, Q Du, X Jing, X He, J Wu, Y Zhang, H Morikawa, M Nakamura, M Scherzer, X Sun, Y Xu, T Cheng, X Li, X Liu, Q Li, Y Liu, A Hong, Y Chen, Y Cao
Nat Commun, 2020-07-24;11(1):3704.
Species: Mouse
Sample Types: Cell Culture Supernates
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Anti-diabetic activity of field cricket glycosaminoglycan by ameliorating oxidative stress
Authors: MY Ahn, BJ Kim, HJ Kim, JM Jin, HJ Yoon, JS Hwang, BM Lee
BMC Complement Med Ther, 2020-07-22;20(1):232.
Species: Mouse
Sample Types: cell culture
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Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages
Authors: K Maruyama, H Kidoya, N Takemura, E Sugisawa, O Takeuchi, T Kondo, MMA Eid, H Tanaka, MM Martino, N Takakura, Y Takayama, S Akira, A Vandenbon, Y Kumagai
Cell Rep, 2020-07-14;32(2):107906.
Species: Mouse
Sample Types: Serum
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Modulation of Macrophage Polarization by Phospholipids on the Surface of Titanium
Authors: H Quan, Y Kim, L Wu, HC Park, HC Yang
Molecules, 2020-06-10;25(11):.
Species: Mouse
Sample Types: Cell Culture Supernates
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The neovascularization effect of dedifferentiated fat cells
Authors: H Watanabe, S Goto, R Kato, S Komiyama, Y Nagaoka, T Kazama, C Yamamoto, Y Li, N Konuma, K Hagikura, T Matsumoto
Sci Rep, 2020-06-08;10(1):9211.
Species: Mouse
Sample Types: Cell Culture Supernates
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Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid metabolism act inversely on tumor progression
Authors: S Huerta-Yep, A Tirado-Rod, MR Montecillo, J Yang, BD Hammock, O Hankinson
Sci Rep, 2020-05-12;10(1):7843.
Species: Mouse
Sample Types: Serum
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Topical Application of Hyaluronic Acid-RGD Peptide-Coated Gelatin/Epigallocatechin-3 Gallate (EGCG) Nanoparticles Inhibits Corneal Neovascularization Via Inhibition of VEGF Production
Authors: T Miyagawa, ZY Chen, CY Chang, KH Chen, YK Wang, GS Liu, CL Tseng
Pharmaceutics, 2020-04-28;12(5):.
Species: Mouse
Sample Types: Tissue Homogenates
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Glial type specific regulation of CNS angiogenesis by HIFalpha-activated different signaling pathways
Authors: S Zhang, B Kim, X Zhu, X Gui, Y Wang, Z Lan, P Prabhu, K Fond, A Wang, F Guo
Nat Commun, 2020-04-24;11(1):2027.
Species: Mouse
Sample Types: Cell Culture Supernates
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Loss of S6K1 But Not S6K2 in the Tumor Microenvironment Suppresses Tumor Growth by Attenuating Tumor Angiogenesis
Authors: S Lee, HS Roh, SS Song, J Shin, J Lee, DH Bhang, BG Kim, SH Um, HS Jeong, KH Baek
Transl Oncol, 2020-04-03;13(4):100767.
Species: Mouse
Sample Types: Cell Culture Supernates
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Protease-activated receptor-2 accelerates intestinal tumor formation through activation of nuclear factor-&kappaB signaling and tumor angiogenesis in ApcMin/+ mice
Authors: M Kawaguchi, K Yamamoto, H Kataoka, A Izumi, F Yamashita, T Kiwaki, T Nishida, E Camerer, T Fukushima
Cancer Sci., 2020-02-24;111(4):1193-1202.
Species: Human
Sample Types: Cell Culture Supernates
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HIV-1 Transcription Inhibitor 1E7-03 Restores LPS-Induced Alteration of Lung Leukocytes' Infiltration Dynamics and Resolves Inflammation in HIV Transgenic Mice
Authors: M Jerebtsova, A Ahmad, X Niu, O Rutagarama, S Nekhai
Viruses, 2020-02-12;12(2):.
Species: Mouse
Sample Types: Plasma
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Calcium dobesilate reduces VEGF signaling by interfering with heparan sulfate binding site and protects from vascular complications in diabetic mice
Authors: F Njau, N Shushakova, H Schenk, VC Wulfmeyer, R Bollin, J Menne, H Haller
PLoS ONE, 2020-01-14;15(1):e0218494.
Species: Mouse
Sample Types: Tissue Lysates
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Glial type specific regulation of CNS angiogenesis by HIFalpha-activated different signaling pathways
Authors: S Zhang, B Kim, X Zhu, X Gui, Y Wang, Z Lan, P Prabhu, K Fond, A Wang, F Guo
Nat Commun, 2020;11(1):2027.
Species: Mouse
Sample Types: Cell Culture Supernates
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Blocking endothelial apoptosis revascularises the retina in a model of ischemic retinopathy
Authors: ZL Grant, L Whitehead, VHY Wong, Z He, RY Yan, AR Miles, AV Benest, DO Bates, C Prahst, K Bentley, BV Bui, RC Symons, L Coultas
J. Clin. Invest., 2020;0(0):.
Species: Mouse
Sample Types: Tissue Lysates
Applications: IHC -
Development of Kaempferol-Loaded Gelatin Nanoparticles for the Treatment of Corneal Neovascularization in Mice
Authors: YL Chuang, HW Fang, A Ajitsaria, KH Chen, CY Su, GS Liu, CL Tseng
Pharmaceutics, 2019-11-28;11(12):.
Species: Mouse
Sample Types: Tissue Homogenates
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Autophagy regulates the therapeutic potential of adipose-derived stem cells in LPS-induced pulmonary microvascular barrier damage
Authors: C Li, J Pan, L Ye, H Xu, B Wang, H Xu, L Xu, T Hou, D Zhang
Cell Death Dis, 2019-10-23;10(11):804.
Species: Mouse
Sample Types: Cell Culture Supernates
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Gastrointestinal tract dysbiosis enhances distal tumor progression through suppression of leukocyte trafficking
Authors: SV Jenkins, MS Robeson, RJ Griffin, CM Quick, ER Siegel, MJ Cannon, KB Vang, RPM Dings
Cancer Res., 2019-10-07;0(0):.
Species: Mouse
Sample Types: Serum
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Mesenchymal stem cell-derived conditioned medium attenuate angiotensin II-induced aortic aneurysm growth by modulating macrophage polarization
Authors: YZ Zhou, Z Cheng, Y Wu, QY Wu, XB Liao, Y Zhao, JM Li, XM Zhou, XM Fu
J. Cell. Mol. Med., 2019-10-04;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Loss of secretin results in systemic and pulmonary hypertension with cardiopulmonary pathologies in mice
Authors: AM Zaw, R Sekar, SOK Mak, HKW Law, BKC Chow
Sci Rep, 2019-10-02;9(1):14211.
Species: Mouse
Sample Types: BALF
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Effects of Photodynamic Therapy with Redaporfin on Tumor Oxygenation and Blood Flow in a Lung Cancer Mouse Model
Authors: M Karwicka, B Pucelik, M Gonet, M Elas, JM D?browski
Sci Rep, 2019-09-02;9(1):12655.
Species: Mouse
Sample Types: Tissue Lysates
-
A ZEB1/p53 signaling axis in stromal fibroblasts promotes mammary epithelial tumours
Authors: R Fu, CF Han, T Ni, L Di, LJ Liu, WC Lv, YR Bi, N Jiang, Y He, HM Li, S Wang, H Xie, BA Chen, XS Wang, SJ Weiss, T Lu, QL Guo, ZQ Wu
Nat Commun, 2019-07-19;10(1):3210.
Species: Mouse
Sample Types: Cell Lysates
-
Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing
Authors: S Saraswati, SMW Marrow, LA Watch, PP Young
Nat Commun, 2019-07-09;10(1):3027.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Evaluation of Neurosecretome from Mesenchymal Stem Cells Encapsulated in Silk Fibroin Hydrogels
Authors: Y Martín-Mar, L Fernández-, MH Sanchez-Re, N Marí-Buyé, FJ Rojo, J Pérez-Rigu, M Ramos, GV Guinea, F Panetsos, D González-N
Sci Rep, 2019-06-19;9(1):8801.
Species: Mouse
Sample Types: Cell Culture Supernates
-
IL-11 is essential in promoting osteolysis in breast cancer bone metastasis via RANKL-independent activation of osteoclastogenesis
Authors: M Liang, Q Ma, N Ding, F Luo, Y Bai, F Kang, X Gong, R Dong, J Dai, Q Dai, C Dou, S Dong
Cell Death Dis, 2019-04-30;10(5):353.
Species: Mouse
Sample Types: Serum
-
The Effect of Electronic-Cigarette Vaping on Cardiac Function and Angiogenesis in Mice
Authors: H Shi, X Fan, A Horton, ST Haller, DJ Kennedy, IT Schiefer, L Dworkin, CJ Cooper, J Tian
Sci Rep, 2019-03-11;9(1):4085.
Species: Mouse
Sample Types: Plasma
-
Tumor suppressor microRNA-204-5p regulates growth, metastasis, and immune microenvironment remodeling in breast cancer
Authors: BS Hong, HS Ryu, N Kim, J Kim, E Lee, H Moon, KH Kim, MS Jin, NH Kwon, S Kim, D Kim, DH Chung, K Jeong, K Kim, KY Kim, HB Lee, W Han, J Yun, JI Kim, DY Noh, HG Moon
Cancer Res., 2019-02-08;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation
Authors: M Subileau, G Merdzhanov, D Ciais, V Collin-Fau, JJ Feige, S Bailly, D Vittet
Stem Cell Reports, 2018-12-27;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice
Authors: C Ozek, RC Krolewski, SM Buchanan, LL Rubin
Sci Rep, 2018-11-23;8(1):17293.
Species: Mouse
Sample Types: Serum
-
Bioengineering Human Neurological Constructs Using Decellularized Meningeal Scaffolds for Application in Spinal Cord Injury.
Authors: Sandeep Kumar Vishwakarm, Avinash Bardia, Chandrakala Lakkiredd, Syed Ameer Basha Paspala, Aleem Ahmed Khan
Frontiers in Bioengineering and Biotechnology, 2018-11-01;0(0):2296-4185.
Species: Xenograft
Sample Types: Tissue Homogenates
-
Thrombocytopenia is associated with severe retinopathy of prematurity
Authors: B Cakir, R Liegl, G Hellgren, P Lundgren, Y Sun, S Klevebro, C Löfqvist, C Mannheimer, S Cho, A Poblete, R Duran, B Hallberg, J Canas, V Lorenz, ZJ Liu, MC Sola-Visne, LE Smith, A Hellström
JCI Insight, 2018-10-04;3(19):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models
Authors: F Sasaki, T Koga, M Ohba, K Saeki, T Okuno, K Ishikawa, T Nakama, S Nakao, S Yoshida, T Ishibashi, H Ahmadieh, MR Kanavi, A Hafezi-Mog, JM Penninger, KH Sonoda, T Yokomizo
JCI Insight, 2018-09-20;3(18):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer
Authors: M Ouarné, C Bouvard, G Boneva, C Mallet, J Ribeiro, A Desroches-, E Soleilhac, E Tillet, O Peyruchaud, S Bailly
J. Exp. Clin. Cancer Res., 2018-08-30;37(1):209.
Species: Mouse
Sample Types: Plasma
-
Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer
Authors: J Steenbrugg, K Breyne, K Demeyere, O De Wever, NN Sanders, W Van Den Br, C Colpaert, P Vermeulen, S Van Laere, E Meyer
J. Exp. Clin. Cancer Res., 2018-08-15;37(1):191.
Species: Mouse
Sample Types: Serum
-
Glycemic Variability Promotes Both Local Invasion and Metastatic Colonization by Pancreatic Ductal Adenocarcinoma
Authors: Z Jian, T Cheng, Z Zhang, S Raulefs, K Shi, K Steiger, N Maeritz, K Kleigrewe, T Hofmann, S Benitz, P Bruns, D Lamp, M Jastroch, J Akkan, C Jäger, P Huang, S Nie, S Shen, X Zou, GO Ceyhan, CW Michalski, H Friess, J Kleeff, B Kong
Cell Mol Gastroenterol Hepatol, 2018-07-26;6(4):429-449.
Species: Mouse
Sample Types: Cell Culture Supernates
-
PAPP-A2 deficiency does not exacerbate the phenotype of a mouse model of intrauterine growth restriction
Authors: JK Christians, KI Lennie, MF Huicochea, N Binning
Reprod. Biol. Endocrinol., 2018-06-12;16(1):58.
Species: Mouse
Sample Types: Serum
-
Treatment of Cutaneous Ulcers with Multilayered Mixed Sheets of Autologous Fibroblasts and Peripheral Blood Mononuclear Cells
Authors: T Mizoguchi, K Ueno, Y Takeuchi, M Samura, R Suzuki, T Murata, T Hosoyama, N Morikage, K Hamano
Cell. Physiol. Biochem., 2018-05-10;47(1):201-211.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration
Authors: T Koo, SW Park, DH Jo, D Kim, JH Kim, HY Cho, J Kim, JH Kim, JS Kim
Nat Commun, 2018-05-10;9(1):1855.
Species: Mouse
Sample Types: Tissue Homogenates
-
Tumor-independent host secretomes induced by angiogenesis and immune-checkpoint inhibitors
Authors: M Mastri, CR Lee, A Tracz, RS Kerbel, M Dolan, Y Shi, JML Ebos
Mol. Cancer Ther., 2018-04-25;0(0):.
Species: Mouse
Sample Types: Plasma
-
EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF
Authors: E Groppa, S Brkic, A Uccelli, G Wirth, P Korpisalo-, M Filippova, B Dasen, V Sacchi, MG Muraro, M Trani, S Reginato, R Gianni-Bar, S Ylä-Herttu, A Banfi
EMBO Rep., 2018-04-11;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
-
Growth Hormone Improves Cognitive Function After Experimental Stroke
Authors: LK Ong, WZ Chow, C TeBay, M Kluge, G Pietrogran, K Zalewska, P Crock, ND Åberg, A Bivard, SJ Johnson, FR Walker, M Nilsson, J Isgaard
Stroke, 2018-04-10;0(0):.
Species: Mouse
Sample Types: Serum
-
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production
Authors: A Longchamp, T Mirabella, A Arduini, MR MacArthur, A Das, JH Treviño-Vi, C Hine, I Ben-Sahra, NH Knudsen, LE Brace, J Reynolds, P Mejia, M Tao, G Sharma, R Wang, JM Corpataux, JA Haefliger, KH Ahn, CH Lee, BD Manning, DA Sinclair, CS Chen, CK Ozaki, JR Mitchell
Cell, 2018-03-22;173(1):117-129.e14.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bevacizumab Promotes T-Cell-Mediated Collagen Deposition in the Mouse Model of Conjunctival Scarring
Authors: LF Seet, LZ Toh, S Chu, SN Finger, F Ginhoux, W Hong, TT Wong
Invest. Ophthalmol. Vis. Sci., 2018-03-01;59(3):1682-1692.
Species: Mouse
Sample Types: Tissue Homogenates
-
Combinations of Bevacizumab and Erlotinib show activity in colorectal cancer independent of RAS status
Authors: P Mésange, A Bouygues, N Ferrand, M Sabbah, AE Escargueil, A Savina, B Chibaudel, C Tournigand, T Andre, A de Gramont, AK Larsen
Clin. Cancer Res., 2018-02-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
-
Surfactant-free solubilization and systemic delivery of anti-cancer drug using low molecular weight methylcellulose
Authors: JY Chung, JH Ko, YJ Lee, HS Choi, YH Kim
J Control Release, 2018-02-21;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Triiodothyronine stimulates VEGF expression and secretion via steroids and HIF-1? in murine Leydig cells
Authors: B Dhole, S Gupta, SK Venugopal, A Kumar
Syst Biol Reprod Med, 2018-02-08;0(0):1-11.
Species: Human
Sample Types: Cell Culture Supernates
-
Potential benefits of mesenchymal stem cells and electroacupuncture on the trophic factors associated with neurogenesis in mice with ischemic stroke
Authors: YR Kim, SM Ahn, ME Pak, HJ Lee, DH Jung, YI Shin, HK Shin, BT Choi
Sci Rep, 2018-02-01;8(1):2044.
Species: Mouse
Sample Types: Tissue Homogenates
-
Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis
Authors: M Nagao, JL Hamilton, R Kc, AD Berendsen, X Duan, CW Cheong, X Li, HJ Im, BR Olsen
Sci Rep, 2017-10-12;7(1):13027.
Species: Mouse
Sample Types: Cell Culture Supernates, Cell Lysates
-
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
Authors: L Kumar Dube, P Karempudi, SA Luther, B Ludewig, NL Harris
Nat Commun, 2017-08-28;8(1):367.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Intermittent hypoxia increases kidney tumor vascularization in a murine model of sleep apnea
Authors: A Vilaseca, N Campillo, M Torres, M Musquera, D Gozal, JM Montserrat, A Alcaraz, KA Touijer, R Farré, I Almendros
PLoS ONE, 2017-06-08;12(6):e0179444.
Species: Mouse
Sample Types: Plasma
-
CXCL1 is critical for pre-metastatic niche formation and metastasis in colorectal cancer
Authors: D Wang, H Sun, J Wei, B Cen, RN DuBois
Cancer Res., 2017-04-28;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
-
Experimental Anterior Ischemic Optic Neuropathy in Diabetic Mice Exhibited Severe Retinal Swelling Associated With VEGF Elevation
Authors: MH Sun, MA Shariati, YJ Liao
Invest. Ophthalmol. Vis. Sci., 2017-04-01;58(4):2296-2305.
Species: Mouse
Sample Types: Serum
-
ANG1 treatment reduces muscle pathology and prevents a decline in perfusion in DMD mice
Authors: KM Gutpell, N Tasevski, B Wong, WT Hrinivich, F Su, J Hadway, L Desjardins, TY Lee, LM Hoffman
PLoS ONE, 2017-03-23;12(3):e0174315.
Species: Mouse
Sample Types: Tissue Homogenates
-
Induction of erythropoiesis by hypoxia-inducible factor prolyl hydroxylase inhibitors without promotion of tumor initiation, progression, or metastasis in a VEGF-sensitive model of spontaneous breast cancer
Authors: TW Seeley, MD Sternlicht, SJ Klaus, TB Neff, DY Liu
Hypoxia (Auckl), 2017-03-10;5(0):1-9.
Species: Mouse
Sample Types: Plasma
-
Motor neurons control blood vessel patterning in the developing spinal cord
Authors: P Himmels, I Paredes, H Adler, A Karakatsan, R Luck, HH Marti, O Ermakova, E Rempel, ET Stoeckli, C Ruiz de Al
Nat Commun, 2017-03-06;8(0):14583.
Species: Mouse
Sample Types: Tissue Homogenates
-
In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
Authors: E Kim, T Koo, SW Park, D Kim, K Kim, HY Cho, DW Song, KJ Lee, MH Jung, S Kim, JH Kim, JH Kim, JS Kim
Nat Commun, 2017-02-21;8(0):14500.
Species: Mouse
Sample Types: Tissue Homogenates
-
Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol and 8-prenylnaringenin: Unveiling the angiogenic paradox and metabolism interplay
Authors: Raquel Costa
Mol Nutr Food Res, 2017-01-30;0(0):.
Species: Mouse
Sample Types: Plasma
-
Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-? Peptide Generation In Vivo
Authors: A Serrano-Po, MA S nchez-Ga, A Heras-Garv, R March-D¡az, V Navarro, M Vizuete, J L¢pez-Barn, J Vitorica, A Pascual
PLoS ONE, 2017-01-18;12(1):e0170345.
Species: Mouse
Sample Types: Tissue Homogenates
-
The biomechanical properties of an epithelial tissue determine the location of its vasculature
Nat Commun, 2016-12-20;7(0):13560.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Renin-Angiotensin System Transgenic Mouse Model Recapitulates Pathophysiology Similar to Human Preeclampsia with Renal Injury that may be Mediated through VEGF
Authors: J Morgan Denney
Am. J. Physiol. Renal Physiol, 2016-12-07;0(0):ajprenal.0010.
Species: Mouse
Sample Types: Plasma
-
Exercise restores muscle stem cell mobilization, regenerative capacity and muscle metabolic alterations via adiponectin/AdipoR1 activation in SAMP10 mice
Authors: Aiko Inoue
J Cachexia Sarcopenia Muscle, 2016-11-29;0(0):.
Species: Mouse
Sample Types: Plasma
-
Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption
PLoS ONE, 2016-11-18;11(11):e0166886.
Species: Mouse
Sample Types: Tissue Homogenates
-
Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS
Authors: Marcelo L M Pereira
Mediators Inflamm, 2016-11-15;2016(0):4158698.
Species: Mouse
Sample Types: Serum
-
First steps to define murine amniotic fluid stem cell microenvironment
Sci Rep, 2016-11-15;6(0):37080.
Species: Mouse
Sample Types: Amniotic Fluid
-
Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism
Nat Commun, 2016-09-01;7(0):12680.
Species: Mouse
Sample Types: Tissue Homogenates
-
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat
Nat Commun, 2016-08-05;7(0):12152.
Species: Mouse
Sample Types: Tissue Homogenates
-
Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus
Authors: Joon W Shim
Sci Rep, 2016-05-31;6(0):26794.
Species: Mouse
Sample Types: CSF
-
Exercise-like effects by Estrogen-related receptor-gamma in muscle do not prevent insulin resistance in db/db mice
Sci Rep, 2016-05-25;6(0):26442.
Species: Mouse
Sample Types: Tissue Homogenates
-
Monocyte chemotactic protein-1 deficiency reduces spontaneous metastasis of Lewis lung carcinoma in mice fed a high-fat diet
Oncotarget, 2016-04-26;7(17):24792-9.
Species: Mouse
Sample Types: Plasma
-
Comparative systems pharmacology of HIF stabilization in the prevention of retinopathy of prematurity
Authors: G Hoppe, S Yoon, B Gopalan, AR Savage, R Brown, K Case, A Vasanji, ER Chan, RB Silver, JE Sears
Proc Natl Acad Sci USA, 2016-04-18;0(0):.
Species: Mouse
Sample Types: Serum
-
Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1
Nat. Med., 2016-03-14;22(4):439-45.
Species: Mouse
Sample Types: Tissue Homogenates
-
Rac1 Regulates Endometrial Secretory Function to Control Placental Development.
Authors: Davila J, Laws M, Kannan A, Li Q, Taylor R, Bagchi M, Bagchi I
PLoS Genet, 2015-08-25;11(8):e1005458.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy.
Authors: Hughes R, Qian B, Rowan C, Muthana M, Keklikoglou I, Olson O, Tazzyman S, Danson S, Addison C, Clemons M, Gonzalez-Angulo A, Joyce J, De Palma M, Pollard J, Lewis C
Cancer Res, 2015-08-12;75(17):3479-91.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The Immune Interplay between Thyroid Papillary Carcinoma and Hepatic Fibrosis.
Authors: Muhanna N, Amer J, Salhab A, Sichel J, Safadi R
PLoS ONE, 2015-07-07;10(7):e0132463.
Species: Mouse
Sample Types: Serum
-
Neutrophil Depletion Attenuates Placental Ischemia-Induced Hypertension in the Rat.
Authors: Regal J, Lillegard K, Bauer A, Elmquist B, Loeks-Johnson A, Gilbert J
PLoS ONE, 2015-07-02;10(7):e0132063.
Species: Rat
Sample Types: Plasma
-
Microangiopathy triggers, and inducible nitric oxide synthase exacerbates dextran sulfate sodium-induced colitis.
Authors: Saijo H, Tatsumi N, Arihiro S, Kato T, Okabe M, Tajiri H, Hashimoto H
Lab Invest, 2015-05-04;95(7):728-48.
Species: Mouse
Sample Types: Serum
-
Anti-angiogenic effect of metformin in mouse oxygen-induced retinopathy is mediated by reducing levels of the vascular endothelial growth factor receptor Flk-1.
Authors: Joe, Soo Geun, Yoon, Young He, Choi, Jeong A, Koh, Jae-Youn
PLoS ONE, 2015-03-18;10(3):e0119708.
Species: Mouse
Sample Types: Tissue Homogenates
-
Investigation of retinal morphology alterations using spectral domain optical coherence tomography in a mouse model of retinal branch and central retinal vein occlusion.
Authors: Ebneter, Andreas, Agca, Cavit, Dysli, Chantal, Zinkernagel, Martin S
PLoS ONE, 2015-03-16;10(3):e0119046.
Species: Mouse
Sample Types: Tissue Homogenates
-
Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
J Transl Med, 2015-02-21;13(0):67.
Species: Mouse
Sample Types: BALF
-
Gain of HIF-1alpha under normoxia in cancer mediates immune adaptation through the AKT/ERK and VEGFA axes.
Authors: Lee Y, Bae H, Noh K, Song K, Ye S, Mao C, Lee K, Wu T, Kim T
Clin Cancer Res, 2015-01-14;21(6):1438-46.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Regulated in development and DNA damage 1 is necessary for hyperglycemia-induced vascular endothelial growth factor expression in the retina of diabetic rodents.
Authors: Dennis M, Kimball S, Fort P, Jefferson L
J Biol Chem, 2014-12-29;290(6):3865-74.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Accelerated tumor progression in mice lacking the ATP receptor P2X7.
Authors: Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, Sarti A, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen N, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F
Cancer Res, 2014-12-26;75(4):635-44.
Species: Mouse
Sample Types: Plasma
-
Long-chain fatty acid analogues suppress breast tumorigenesis and progression.
Authors: Gluschnaider U, Hertz R, Ohayon S, Smeir E, Smets M, Pikarsky E, Bar-Tana J
Cancer Res, 2014-10-10;74(23):6991-7002.
Species: Mouse
Sample Types: Tissue Homogenates
-
Capillary force seeding of hydrogels for adipose-derived stem cell delivery in wounds.
Authors: Garg R, Rennert R, Duscher D, Sorkin M, Kosaraju R, Auerbach L, Lennon J, Chung M, Paik K, Nimpf J, Rajadas J, Longaker M, Gurtner G
Stem Cells Transl Med, 2014-07-18;3(9):1079-89.
Species: Mouse
Sample Types: Protein
-
Mitigation of oxygen-induced retinopathy in alpha2beta1 integrin-deficient mice.
Authors: Madamanchi A, Capozzi M, Geng L, Li Z, Friedman R, Dickeson S, Penn J, Zutter M
Invest Ophthalmol Vis Sci, 2014-06-10;55(7):4338-47.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Alcohol promotes mammary tumor growth through activation of VEGF-dependent tumor angiogenesis.
Authors: Lu, Yanmin, Ni, Fang, Xu, Mei, Yang, Jinlian, Chen, Ji, Chen, Zhuo, Wang, Xinyi, Luo, Jia, Wang, Siying
Oncol Lett, 2014-05-16;8(2):673-678.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations.
Authors: Januszyk M, Sorkin M, Glotzbach J, Vial I, Maan Z, Rennert R, Duscher D, Thangarajah H, Longaker M, Butte A, Gurtner G
Diabetes, 2014-04-16;63(9):3047-56.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction.
Authors: Malliaras K, Ibrahim A, Tseliou E, Liu W, Sun B, Middleton R, Seinfeld J, Wang L, Sharifi B, Marban E
EMBO Mol Med, 2014-04-06;6(6):760-77.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
J Biol Chem, 2014-03-13;289(16):11522-35.
Species: Mouse
Sample Types: Whole Cells
-
Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury.
Authors: Piccioni A, Gaetani E, Palladino M, Gatto I, Smith R, Neri V, Marcantoni M, Giarretta I, Silver M, Straino S, Capogrossi M, Landolfi R, Pola R
Gene Ther, 2014-02-27;21(4):413-21.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Advances in the pathophysiology of pre-eclampsia and related podocyte injury.
Authors: Craici, Iasmina, Wagner, Steven J, Weissgerber, Tracey L, Grande, Joseph P, Garovic, Vesna D
Kidney Int, 2014-02-26;86(2):275-85.
Species: Rat
Sample Types:
-
Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice.
Authors: Turunen M, Husso T, Musthafa H, Laidinen S, Dragneva G, Laham-Karam N, Honkanen S, Paakinaho A, Laakkonen J, Gao E, Vihinen-Ranta M, Liimatainen T, Yla-Herttuala S
PLoS ONE, 2014-02-26;9(2):e89979.
Species: Mouse
Sample Types: Tissue Homogenates
-
Anthocyanin-rich purple corn extract inhibit diabetes-associated glomerular angiogenesis.
Authors: Kang M, Lim S, Lee J, Yeo K, Kang Y
PLoS ONE, 2013-11-20;8(11):e79823.
Species: Mouse
Sample Types: Plasma
-
Cilostazol improves the response to ischemia in diabetic mice by a mechanism dependent on PPARgamma.
Authors: Biscetti F, Pecorini G, Arena V, Stigliano E, Angelini F, Ghirlanda G, Ferraccioli G, Flex A
Mol Cell Endocrinol, 2013-07-23;381(1):80-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia.
Authors: Madonna R, Taylor D, Geng Y, De Caterina R, Shelat H, Perin E, Willerson J
Circ Res, 2013-06-18;113(7):902-14.
Species: Mouse
Sample Types: Cell Culture Supernates
-
The impact of KRAS mutations on VEGF-A production and tumour vascular network.
Authors: Figueras A, Arbos M, Quiles M, Vinals F, Germa J, Capella G
BMC Cancer, 2013-03-18;13(0):125.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer.
Authors: Leifler K, Svensson S, Abrahamsson A, Bendrik C, Robertson J, Gauldie J, Olsson A, Dabrosin C
J Immunol, 2013-03-15;190(8):4420-30.
Species: Mouse
Sample Types: Tissue Homogenates
-
Matrix protein of vesicular stomatitis virus: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation.
Authors: Zhou Y, Wen F, Zhang P, Tang R, Li Q
Cancer Gene Ther, 2013-03-01;20(3):178-85.
Species: Mouse
Sample Types: Plasma
-
Suppression of laser-induced choroidal neovascularization by a CCR3 antagonist.
Authors: Mizutani, Takeshi, Ashikari, Masayuki, Tokoro, Mayumi, Nozaki, Miho, Ogura, Yuichiro
Invest Ophthalmol Vis Sci, 2013-02-28;54(2):1564-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
Stem Cells, 2013-01-01;31(1):203-14.
Species: Mouse
Sample Types: Tissue Homogenates
-
Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct.
Authors: Bleiziffer O, Hammon M, Arkudas A, Taeger C, Beier J, Amann K, Naschberger E, Sturzl M, Horch R, Kneser U
BMC Biotechnol, 2012-12-06;12(0):94.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibitory effect of the combination therapy of simvastatin and pinocembrin on atherosclerosis in ApoE-deficient mice.
Authors: Sang, Hui, Yuan, Na, Yao, Shutong, Li, Furong, Wang, Jiafu, Fang, Yongqi, Qin, Shucun
Lipids Health Dis, 2012-12-05;11(0):166.
Species: Mouse
Sample Types: Serum
-
Hypoxia-inducible Factor-1 (HIF-1) but Not HIF-2 Is Essential for Hypoxic Induction of Collagen Prolyl 4-Hydroxylases in Primary Newborn Mouse Epiphyseal Growth Plate Chondrocytes.
Authors: Aro E, Khatri R
J. Biol. Chem., 2012-08-28;287(44):37134-44.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.
Clin. Cancer Res., 2012-07-24;18(18):5031-42.
Species: Mouse
Sample Types: Plasma
-
Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing.
Authors: Ko SH, Nauta A, Morrison SD, Zhou H, Zimmermann A, Gurtner GC, Ding S, Longaker MT
PLoS ONE, 2011-11-18;6(11):e27844.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TIEG1 inhibits breast cancer invasion and metastasis by inhibition of epidermal growth factor receptor (EGFR) transcription and the EGFR signaling pathway.
Authors: Jin W, Chen BB, Li JY, Zhu H, Huang M, Gu SM, Wang QQ, Chen JY, Yu S, Wu J, Shao ZM
Mol. Cell. Biol., 2011-10-24;32(1):50-63.
Species: Mouse
Sample Types: Serum
-
HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
Authors: Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD
PLoS Genet., 2011-10-20;7(10):e1002336.
Species: Mouse
Sample Types: Serum
-
Caloric restriction reduces growth of mammary tumors and metastases.
Authors: De Lorenzo M, Baljinnyam E, Vatner D, Abarzua P, Vatner S, Rabson A
Carcinogenesis, 2011-06-10;32(9):1381-7.
Species: Mouse
Sample Types: Serum
-
Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization.
Authors: Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS
J. Biol. Chem., 2011-04-22;286(23):20991-1001.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-17 and VEGF are necessary for efficient corneal nerve regeneration.
Authors: Li Z, Burns AR, Han L, Rumbaut RE, Smith CW
Am. J. Pathol., 2011-03-01;178(3):1106-16.
Species: Mouse
Sample Types: Tissue Homogenates
-
Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor.
Authors: Suryawanshi A, Mulik S, Sharma S
J. Immunol., 2011-02-16;186(6):3653-65.
Species: Mouse
Sample Types: Tissue Homogenates
-
Conditional HIF-1 induction produces multistage neovascularization with stage-specific sensitivity to VEGFR inhibitors and myeloid cell independence.
Authors: Oladipupo SS, Hu S, Santeford AC, Yao J, Kovalski JR, Shohet RV, Maslov K, Wang LV, Arbeit JM
Blood, 2011-02-09;117(15):4142-53.
Species: Human, Mouse
Sample Types: Plasma, Tissue Homogenates
-
Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1.
Authors: Ruiz de Almodovar C, Coulon C, Salin PA, Knevels E, Chounlamountri N, Poesen K, Hermans K, Lambrechts D, Van Geyte K, Dhondt J, Dresselaers T, Renaud J, Aragones J, Zacchigna S, Geudens I, Gall D, Stroobants S, Mutin M, Dassonville K, Storkebaum E, Jordan BF, Eriksson U, Moons L, D'Hooge R, Haigh JJ, Belin MF, Schiffmann S, Van Hecke P, Gallez B, Vinckier S, Chedotal A, Honnorat J, Thomasset N, Carmeliet P, Meissirel C
J. Neurosci., 2010-11-10;30(45):15052-66.
Species: Mouse
Sample Types: Tissue Homogenates
-
Placental growth factor mediates aldosterone-dependent vascular injury in mice.
Authors: Jaffe IZ, Newfell BG, Aronovitz M
J. Clin. Invest., 2010-11-01;120(11):3891-900.
Species: Mouse
Sample Types: Tissue Homogenates
-
Regulation of pathologic retinal angiogenesis in mice and inhibition of VEGF-VEGFR2 binding by soluble heparan sulfate.
Authors: Nishiguchi KM, Kataoka K, Kachi S
PLoS ONE, 2010-10-20;5(10):e13493.
Species: Mouse
Sample Types: Aqueous Humor
-
Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.
Authors: Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D
J. Immunol., 2010-10-13;185(10):6306-16.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
Authors: Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T
Oncogene, 2010-09-06;30(1):54-64.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer.
Authors: Lan KL, Ou-Yang F, Yen SH, Shih HL, Lan KH
Clin. Exp. Metastasis, 2010-04-07;27(5):307-18.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Inhibition of EGFR pathway signaling and the metastatic potential of breast cancer cells by PA-MSHA mediated by type 1 fimbriae via a mannose-dependent manner.
Authors: Liu ZB, Hou YF, Zhu J
Oncogene, 2010-03-15;29(20):2996-3009.
Species: Mouse
Sample Types: Serum
-
Functions of type II pneumocyte-derived vascular endothelial growth factor in alveolar structure, acute inflammation, and vascular permeability.
Authors: Mura M, Binnie M, Han B, Li C, Andrade CF, Shiozaki A, Zhang Y, Ferrara N, Hwang D, Waddell TK, Keshavjee S, Liu M
Am. J. Pathol., 2010-02-18;176(4):1725-34.
Species: Mouse
Sample Types: BALF
-
Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice.
Authors: Marttila-Ichihara F, Castermans K, Auvinen K, oude Egbrink MG, Jalkanen S, Griffioen AW, Salmi M
J. Immunol., 2010-02-12;184(6):3164-73.
Species: Mouse
Sample Types: Serum
-
Platelet-derived growth factor-B normalizes micromorphology and vessel function in vascular endothelial growth factor-A-induced squamous cell carcinomas.
Authors: Lederle W, Linde N, Heusel J, Bzyl J, Woenne EC, Zwick S, Skobe M, Kiessling F, Fusenig NE, Mueller MM
Am. J. Pathol., 2009-12-30;176(2):981-94.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2009-12-29;49(3):256-63.
Species: Mouse
Sample Types: BALF
-
Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular disease.
Authors: Hakroush S, Moeller MJ, Theilig F, Kaissling B, Sijmonsma TP, Jugold M, Akeson AL, Traykova-Brauch M, Hosser H, Hahnel B, Grone HJ, Koesters R, Kriz W
Am. J. Pathol., 2009-10-15;175(5):1883-95.
Species: Mouse
Sample Types: Serum
-
Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis.
Authors: Bilotas M, Meresman G, Stella I, Sueldo C, Baranao RI
Fertil. Steril., 2009-10-12;93(8):2513-8.
Species: Mouse
Sample Types: Peritoneal Fluid
-
The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
Authors: Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T
J. Clin. Invest., 2009-07-13;119(8):2257-70.
Species: Mouse
Sample Types: Plasma
-
Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.
Authors: Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R
Brain Res., 2009-05-18;1280(0):43-51.
Species: Mouse
Sample Types: Serum
-
Disruption of interleukin-1 signaling improves the quality of wound healing.
Authors: Thomay AA, Daley JM, Sabo E, Worth PJ, Shelton LJ, Harty MW, Reichner JS, Albina JE
Am. J. Pathol., 2009-04-23;174(6):2129-36.
Species: Mouse
Sample Types: Tissue Secretion
-
Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
Authors: Wang C, Duan H, He L
Eur. J. Pharmacol., 2009-04-06;612(1):143-52.
Species: Mouse
Sample Types: Air Pouch Exudate
-
Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.
Authors: Sehrawat S, Suryawanshi A, Hirashima M, Rouse BT
J. Immunol., 2009-03-01;182(5):3191-201.
Species: Mouse
Sample Types: Tissue Homogenates
-
Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1.
Authors: Shen HC, He M, Powell A, Adem A, Lorang D, Heller C, Grover AC, Ylaya K, Hewitt SM, Marx SJ, Spiegel AM, Libutti SK
Cancer Res., 2009-02-10;69(5):1858-66.
Species: Mouse
Sample Types: Tissue Homogenates
-
Kallidinogenase normalizes retinal vasopermeability in streptozotocin-induced diabetic rats: potential roles of vascular endothelial growth factor and nitric oxide.
Authors: Kato N, Hou Y, Lu Z, Lu C, Nagano H, Suzuma K, Takagi H, Matsumoto Y
Eur. J. Pharmacol., 2009-01-29;606(1):187-90.
Species: Mouse
Sample Types: Aqueous Humor
-
Deficiency of immunophilin FKBP52 promotes endometriosis.
Authors: Hirota Y, Tranguch S, Daikoku T, Hasegawa A, Osuga Y, Taketani Y, Dey SK
Am. J. Pathol., 2008-11-06;173(6):1747-57.
Species: Mouse
Sample Types: Peritoneal Fluid
-
(Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.
Authors: Satofuka S, Ichihara A, Nagai N, Noda K, Ozawa Y, Fukamizu A, Tsubota K, Itoh H, Oike Y, Ishida S
Am. J. Pathol., 2008-10-30;173(6):1911-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: implications for antiangiogenic drugs as chemosensitizing agents.
Authors: Shaked Y, Henke E, Roodhart JM, Mancuso P, Langenberg MH, Colleoni M, Daenen LG, Man S, Xu P, Emmenegger U, Tang T, Zhu Z, Witte L, Strieter RM, Bertolini F, Voest EE, Benezra R, Kerbel RS
Cancer Cell, 2008-09-09;14(3):263-73.
Species: Mouse
Sample Types: Plasma
-
MicroRNAs regulate ocular neovascularization.
Authors: Shen J, Yang X, Xie B, Chen Y, Swaim M, Hackett SF, Campochiaro PA
Mol. Ther., 2008-05-20;16(7):1208-16.
Species: Mouse
Sample Types: Tissue Homogenates
-
Heme oxygenase-1 promotes neovascularization in ischemic heart by coinduction of VEGF and SDF-1.
Authors: Lin HH, Chen YH, Chang PF, Lee YT, Yet SF, Chau LY
J. Mol. Cell. Cardiol., 2008-05-02;45(1):44-55.
Species: Mouse
Sample Types: Tissue Homogenates
-
Regulation of scar formation by vascular endothelial growth factor.
Authors: Wilgus TA, Ferreira AM, Oberyszyn TM, Bergdall VK, DiPietro LA
Lab. Invest., 2008-04-21;88(6):579-90.
Species: Mouse
Sample Types: Tissue Homogenates
-
An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
Authors: Xie B, Shen J, Dong A, Swaim M, Hackett SF, Wyder L, Worpenberg S, Barbieri S, Campochiaro PA
FASEB J., 2008-04-01;22(8):2775-83.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S
Invest. Ophthalmol. Vis. Sci., 2008-04-01;49(4):1679-85.
Species: Mouse
Sample Types: Tissue Homogenates
-
The aryl hydrocarbon receptor (AhR) inhibits vanadate-induced vascular endothelial growth factor (VEGF) production in TRAMP prostates.
Authors: Fritz WA, Lin TM, Peterson RE
Carcinogenesis, 2008-03-20;29(5):1077-82.
Species: Mouse
Sample Types: Tissue Homogenates
-
Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function.
Authors: Ishida Y, Gao JL, Murphy PM
J. Immunol., 2008-01-01;180(1):569-79.
Species: Mouse
Sample Types: Tissue Homogenates
-
von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Authors: Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC
J. Clin. Invest., 2007-12-01;117(12):3879-3889.
Species: Mouse
Sample Types: Serum
-
Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation.
Authors: Itaya M, Sakurai E, Nozaki M, Yamada K, Yamasaki S, Asai K, Ogura Y
Invest. Ophthalmol. Vis. Sci., 2007-12-01;48(12):5677-83.
Species: Mouse
Sample Types: Tissue Homogenates
-
alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner.
Authors: Zhang Z, Ramirez NE, Yankeelov TE, Li Z, Ford LE, Qi Y, Pozzi A, Zutter MM
Blood, 2007-11-27;111(4):1980-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy.
Authors: Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS
Proc. Natl. Acad. Sci. U.S.A., 2007-10-17;104(43):17069-74.
Species: Mouse
Sample Types: Plasma
-
Macular pigment lutein is antiinflammatory in preventing choroidal neovascularization.
Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Umezawa K, Ohno S, Oike Y, Ishida S
Arterioscler. Thromb. Vasc. Biol., 2007-10-11;27(12):2555-62.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4498-508.
Species: Mouse
Sample Types: Tissue Homogenates
-
Very low density lipoprotein receptor, a negative regulator of the wnt signaling pathway and choroidal neovascularization.
Authors: Chen Y, Hu Y, Lu K, Flannery JG, Ma JX
J. Biol. Chem., 2007-09-23;282(47):34420-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
VEGF receptor inhibition slows the progression of polycystic kidney disease.
Authors: Tao Y, Kim J, Yin Y, Zafar I, Falk S, He Z, Faubel S, Schrier RW, Edelstein CL
Kidney Int., 2007-09-19;72(11):1358-66.
Species: Mouse
Sample Types: Serum
-
Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007-08-01;35(8):1955-60.
Species: Mouse
Sample Types: Plasma
-
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes.
Authors: Halin C, Tobler NE, Vigl B, Brown LF, Detmar M
Blood, 2007-07-11;110(9):3158-67.
Species: Mouse
Sample Types: Tissue Homogenates
-
Inactivation of VEGF in mammary gland epithelium severely compromises mammary gland development and function.
Authors: Rossiter H, Barresi C, Ghannadan M, Gruber F, Mildner M, Fodinger D, Tschachler E
FASEB J., 2007-07-11;21(14):3994-4004.
Species: Mouse
Sample Types: Milk
-
Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP model.
Authors: Isayeva T, Chanda D, Kallman L, Eltoum IE, Ponnazhagan S
Cancer Res., 2007-06-15;67(12):5789-97.
Species: Mouse
Sample Types: Serum
-
HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia.
Authors: Dai Y, Xu M, Wang Y, Pasha Z, Li T, Ashraf M
J. Mol. Cell. Cardiol., 2007-04-06;42(6):1036-44.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Enteric bacteria and their antigens may stimulate postoperative peritoneal adhesion formation.
Authors: Cahill RA, Wang JH, Redmond HP
Surgery, 2007-01-22;141(3):403-10.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.
Authors: Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA
Nat. Med., 2006-11-05;12(11):1286-93.
Species: Mouse
Sample Types: BALF
-
A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex.
Authors: Rafei M, Wu JH, Annabi B, Lejeune L, Francois M, Galipeau J
Blood, 2006-11-02;109(5):2234-42.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential.
Authors: Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal PM, Pesce M, Capogrossi MC, Failla CM, Napolitano M, Odorisio T
Am. J. Pathol., 2006-10-01;169(4):1167-82.
Species: Mouse
Sample Types: Tissue Homogenates
-
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
Authors: Takeda K, Ho VC, Takeda H, Duan LJ, Nagy A, Fong GH
Mol. Cell. Biol., 2006-09-11;26(22):8336-46.
Species: Mouse
Sample Types: Tissue Homogenates
-
Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
Authors: Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
J. Immunol., 2006-09-01;177(5):3388-97.
Species: Mouse
Sample Types: Tissue Homogenates
-
CCL2 regulates angiogenesis via activation of Ets-1 transcription factor.
Authors: Stamatovic SM, Keep RF, Mostarica-Stojkovic M, Andjelkovic AV
J. Immunol., 2006-08-15;177(4):2651-61.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2.
Authors: Yamaji-Kegan K, Su Q, Angelini DJ, Champion HC, Johns RA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-04;291(6):L1159-68.
Species: Mouse, Rat
Sample Types: Cell Culture Supernates
-
Mast cells facilitate local VEGF release as an early event in the pathogenesis of postoperative peritoneal adhesions.
Authors: Cahill RA, Wang JH, Soohkai S, Redmond HP
Surgery, 2006-07-01;140(1):108-12.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Role of peroxisome proliferator-activated receptor-alpha in acute pancreatitis induced by cerulein.
Authors: Genovese T, Mazzon E, Di Paola R, Muia C, Crisafulli C, Malleo G, Esposito E, Cuzzocrea S
Immunology, 2006-06-08;118(4):559-70.
Species: Mouse
Sample Types: Tissue Homogenates
-
Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system.
Authors: Wang CH, Verma S, Hsieh IC, Chen YJ, Kuo LT, Yang NI, Wang SY, Wu MY, Hsu CM, Cheng CW, Cherng WJ
J. Mol. Cell. Cardiol., 2006-05-05;41(1):34-43.
Species: Mouse
Sample Types: Plasma
-
Combination of systemic thioacetamide (TAA) injections and ethanol feeding accelerates hepatic fibrosis in C3H/He mice and is associated with intrahepatic up regulation of MMP-2, VEGF and ICAM-1.
Authors: Kornek M, Raskopf E, Guetgemann I, Ocker M, Gerceker S, Gonzalez-Carmona MA, Rabe C, Sauerbruch T, Schmitz V
J. Hepatol., 2006-05-03;45(3):370-6.
Species: Mouse
Sample Types: Tissue Homogenates
-
Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer.
Authors: Hahn T, Alvarez I, Kobie JJ, Ramanathapuram L, Dial S, Fulton A, Besselsen D, Walker E, Akporiaye ET
Int. J. Cancer, 2006-05-01;118(9):2220-31.
Species: Mouse
Sample Types: Serum
-
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
Cancer Res., 2006-04-15;66(8):4198-207.
Species: Mouse
Sample Types: Tissue Homogenates
-
Increased VEGF levels induced by anti-VEGF treatment are independent of tumor burden in colorectal carcinomas in mice.
Authors: Schmitz V, Vilanueva H, Raskopf E, Hilbert T, Barajas M, Dzienisowicz C, Gorschluter M, Strehl J, Rabe C, Sauerbruch T, Prieto J, Caselmann WH, Qian C
Gene Ther., 2006-04-13;13(16):1198-205.
Species: Mouse
Sample Types: Tissue Homogenates
-
Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice.
Authors: Pourgholami MH, Yan Cai Z, Lu Y, Wang L, Morris DL
Clin. Cancer Res., 2006-03-15;12(6):1928-35.
Species: Mouse
Sample Types: Plasma
-
Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion.
Authors: Stathopoulos GT, Zhu Z, Everhart MB, Kalomenidis I, Lawson WE, Bilaceroglu S, Peterson TE, Mitchell D, Yull FE, Light RW, Blackwell TS
Am. J. Respir. Cell Mol. Biol., 2005-10-06;34(2):142-50.
Species: Mouse
Sample Types: Serum
-
Expression of pulmonary VEGF family declines with age and is further down-regulated in lipopolysaccharide (LPS)-induced lung injury.
Authors: Ito Y, Betsuyaku T, Nagai K, Nasuhara Y, Nishimura M
Exp. Gerontol., 2005-04-01;40(4):315-23.
Species: Mouse
Sample Types: BALF
-
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.
Authors: Jensen KK, Manfra DJ, Grisotto MG, Martin AP, Vassileva G, Kelley K, Schwartz TW, Lira SA
J. Immunol., 2005-03-15;174(6):3686-94.
Species: Mouse
Sample Types: Tissue Homogenates
-
Effect of valsartan versus lisinopril on peritoneal sclerosis in rats.
Authors: Duman S, Sen S, Duman C, Oreopoulos DG
Int J Artif Organs, 2005-02-01;28(2):156-63.
Species: Rat
Sample Types: Peritoneal Dialysate
-
Recombinant adeno-associated virus 2-mediated antiangiogenic prevention in a mouse model of intraperitoneal ovarian cancer.
Authors: Isayeva T, Ren C, Ponnazhagan S
Clin. Cancer Res., 2005-02-01;11(3):1342-7.
Species: Mouse
Sample Types: Ascites Fluid
-
Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
J. Immunol., 2005-01-01;174(1):215-22.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Adeno-associated virus vector-mediated delivery of pigment epithelium-derived factor restricts neuroblastoma angiogenesis and growth.
Authors: Streck CJ, Zhang Y, Zhou J, Ng C, Nathwani AC, Davidoff AM
J. Pediatr. Surg., 2005-01-01;40(1):236-43.
Species: Mouse
Sample Types: Tissue Homogenates
-
Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer.
Authors: Rota R, Riccioni T, Zaccarini M, Lamartina S, Gallo AD, Fusco A, Kovesdi I, Balestrazzi E, Abeni DC, Ali RR, Capogrossi MC
J Gene Med, 2004-09-01;6(9):992-1002.
Species: Rat
Sample Types: Vitreous Humor
-
VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.
Authors: Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, Moore T, Amano S, Horikawa Y, Dartt D, Golding M, Shima DT, Adamis AP
Invest. Ophthalmol. Vis. Sci., 2004-02-01;45(2):368-74.
Species: Mouse
Sample Types: Tissue Homogenates
-
Estrogen regulates the production of VEGF for osteoclast formation and activity in op/op mice.
Authors: Kodama I, Sanada M, Yoshiko Y, Tsuda M, Ohama K
J. Bone Miner. Res., 2003-12-16;19(2):200-6.
Species: Mouse
Sample Types: Serum
-
beta-Catenin regulates vascular endothelial growth factor expression in colon cancer.
Authors: Easwaran V, Lee SH, Inge L, Guo L, Goldbeck C, Garrett E, Wiesmann M, Garcia PD, Fuller JH, Chan V, Randazzo F, Gundel R, Warren RS, Escobedo J, Aukerman SL, Taylor RN, Fantl WJ
Cancer Res., 2003-06-15;63(12):3145-53.
Species: Mouse
Sample Types: Tissue Homogenates
-
Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction.
Authors: Kozawa O, Yoshimi N, Akamatsu S, Hara A, Mori H, Uematsu T
Blood, 2002-10-01;100(7):2487-93.
Species: Mouse
Sample Types: Cell Culture Supernates
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A critical role of placental growth factor in the induction of inflammation and edema formation.
Authors: Oura H, Bertoncini J, Velasco P, Brown LF, Carmeliet P, Detmar M
Blood, 2002-09-05;101(2):560-7.
Species: Mouse
Sample Types: Cell Lysates
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Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand.
Authors: Heissig B, Hattori K, Dias S, Friedrich M, Ferris B, Hackett NR, Crystal RG, Besmer P, Lyden D, Moore MA, Werb Z, Rafii S
Cell, 2002-05-31;109(5):625-37.
Species: Mouse
Sample Types: Plasma
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Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function.
Authors: Margetts PJ, Kolb M, Galt T, Hoff CM, Shockley TR, Gauldie J
J. Am. Soc. Nephrol., 2001-10-01;12(10):2029-39.
Species: Rat
Sample Types: Peritoneal Fluid
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Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.
Authors: Gabrilovich DI, 2018, Ishida T, Nadaf S, Ohm JE, Carbone DP
1537, 1999-10-01;5(10):2963-70.
Species: Mouse
Sample Types: Cell Culture Supernates
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Mouse VEGF was used to quantify this protein in mouse plasma subjected to pro-inflammatory factors (TNF-a, IL-1b, LPS). Results showed a consistent VEGF production that could be quantified.