Home / YM1/Chitinase 3-like 3 / Mouse YM1/Chitinase 3-like 3 Biotinylated Antibody

Mouse YM1/Chitinase 3-like 3 Biotinylated Antibody

Catalog #: BAF2446
12 Citations Datasheet / COA / SDS
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BAF2446
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Citations (12)
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Mouse YM1/Chitinase 3-like 3 Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse YM1/Chitinase 3-like 3 in Western blots. 
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse YM1/Chitinase 3-like 3
Tyr22-Tyr398
Accession # O35744
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse YM1/Chitinase 3-like 3 (Catalog # 2446-CH)

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: YM1/Chitinase 3-like 3

ECF-L, also known as YM1, is a secreted 377 amino acid residue lectin that binds heparin and G1cN oligomers. It is produced primarily by macrophages during inflammation. ECF-L shares homology with chitinase family proteins but lacks enzymatic activity.

Entrez Gene IDs
12655 (Mouse)
Alternate Names
AI505981; CHI3L3; Chitinase 3 like 3; Chitinase 3-like 3; ECF-L; YM1

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Citations for Mouse YM1/Chitinase 3-like 3 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

12 Citations: Showing 1 - 10
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  1. Ongoing Exposure to Peritoneal Dialysis Fluid Alters Resident Peritoneal Macrophage Phenotype and Activation Propensity
    Authors: Tara E. Sutherland, Tovah N. Shaw, Rachel Lennon, Sarah E. Herrick, Dominik Rückerl
    Frontiers in Immunology
  2. Inflammatory and immunopathological differences in brains of permissive and non-permissive hosts with Angiostrongylus cantonensis infection can be identified using 18F/FDG/PET-imaging
    Authors: Chang, KW;Wang, LC;Wang, HY;Lin, TY;Hwu, EE;Cheng, PC;
    PLoS neglected tropical diseases
    Species: Mouse, Rat
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  3. The IL-17A-neutrophil axis promotes epithelial cell IL-33 production during nematode lung migration
    Authors: Ajendra, J;Papotto, PH;Parkinson, JE;Dodd, RJ;Bombeiro, AL;Pearson, S;Chan, BHK;Ribot, JC;McSorley, HJ;Sutherland, TE;Allen, JE;
    Mucosal immunology
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Immunohistochemistry
  4. Monocytes maintain central nervous system homeostasis following helminth-induced inflammation
    Authors: J Peng, CB Sy, JJ Ponessa, AD Lemenze, CM Hernandez, JM Inclan-Ric, A Sawhney, HG Federman, K Chavan, V Espinosa, SV Kotenko, A Rivera, MC Siracusa
    Proceedings of the National Academy of Sciences of the United States of America, 2022-09-07;119(37):e2201645119.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  5. Perampanel Reduces Brain Damage via Induction of M2 Microglia in a Neonatal Rat Stroke Model
    Authors: HJ Shin, KY Lee, JW Kang, SG Choi, DW Kim, YY Yi
    International Journal of Nanomedicine, 2022-06-27;17(0):2791-2804.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  6. Ym1 induces RELM? and rescues IL-4R? deficiency in lung repair during nematode infection
    Authors: TE Sutherland, D Rückerl, N Logan, S Duncan, TA Wynn, JE Allen
    PLoS Pathog., 2018-11-30;14(11):e1007423.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance
    Authors: LR Hoving, HJP van der Za, A Pronk, B Guigas, K Willems va, V van Harmel
    PLoS ONE, 2018-05-03;13(5):e0196165.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  8. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages
    Authors: Z Czimmerer, B Daniel, A Horvath, D Rückerl, G Nagy, M Kiss, M Peloquin, MM Budai, I Cuaranta-M, Z Simandi, L Steiner, B Nagy, S Poliska, C Banko, Z Bacso, IG Schulman, S Sauer, JF Deleuze, JE Allen, S Benko, L Nagy
    Immunity, 2018-01-16;48(1):75-90.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  9. High salt primes a specific activation state of macrophages, M(Na).
    Authors: Zhang W, Zheng X, DU L, Sun J, Shen Z, Shi C, Sun S, Zhang Z, Chen X, Qin M, Liu X, Tao J, Jia L, Fan H, Zhou B, Yu Y, Ying H, Hui L, Liu X, Yi X, Liu X, Zhang L, Duan S
    Cell Res, 2015-07-24;25(8):893-910.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  10. Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model.
    Authors: Mills Ko E, Ma J, Guo F, Miers L, Lee E, Bannerman P, Burns T, Ko D, Sohn J, Soulika A, Pleasure D
    J Neuroinflammation, 2014-06-12;11(0):105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  11. Conditional ablation of astroglial CCL2 suppresses CNS accumulation of M1 macrophages and preserves axons in mice with MOG peptide EAE.
    Authors: Moreno M, Bannerman P, Ma J, Guo F, Miers L, Soulika A, Pleasure D
    J Neurosci, 2014-06-11;34(24):8175-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  12. Explaining the polarized macrophage pool during murine allergic lung inflammation
    Authors: Christina Draijer, Laura Florez-Sampedro, Catharina Reker-Smit, Eduard Post, Fransien van Dijk, Barbro N. Melgert
    Frontiers in Immunology

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