NPEC-caged-(S)-AMPA
Chemical Name: (N)-1-(2-Nitrophenyl)ethylcarboxy-(S)-α-1-(2-nitrophenyl)ethylcarboxyamino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Purity: ≥98%
Biological Activity
NPEC-caged-(S)-AMPA is a 1-(2-nitrophenyl)ethyl caged version of (S)-AMPA (Cat. No. 0254), agonist at the AMPA receptor. Extinction coefficient (ε347) = 660 M-1cm-1, quantum yield (φ) = 0.64. Suitable for near-UV uncaging. No inhibition of GABA-A receptors at concentrations used experimentally.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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New caged neurotransmitter analogs selective for glutamate receptor sub-types based on methoxynitroindoline and nitrophenylethoxycarbonyl caging groups.
Palma-Cerda et al.
Neuropharmacology., 2012;63:624
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