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Recombinant Human TNF-alpha Protein

Catalog #: 210-TA
817 Citations 35 Reviews Datasheet / COA / SDS
GMP Version Available: 210-GMP
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Analyzed by SEC-MALS

Carrier Free

Catalog # Availability Size / Price Qty
210-TA-02M/CF
210-TA-020/CF
210-TA-100/CF
210-TA-005/CF

With Carrier

Catalog # Availability Size / Price Qty
210-TA-020
210-TA-100
210-TA-005
Recombinant Human TNF‑ alpha Protein SEC-MALS.
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Product Details
Citations (817)
FAQs
Supplemental Products
Reviews (35)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Human TNF-alpha Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 221. The ED50 for this effect is 25-100 pg/mL.
Source
E. coli-derived human TNF-alpha protein
Val77-Leu233, with and without an N-terminal Met
Accession #
P01375
N-terminal Sequence
Analysis
Met & Val77
Predicted Molecular Mass
17 kDa
SDS-PAGE
17 kDa, reducing conditions

Product Datasheets

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210-TA (with carrier)

Product Datasheet
COA
SDS

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210-TA/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

210-TA

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 0.1-1 mg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

210-TA/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS. *Small pack size (5 & 20 µg) is supplied as a 0.2 µm filtered solution in PBS. 
Reconstitution Reconstitute at 0.1-1 mg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (5 & 20 µg) is shipped with dry ice or equivalent. Upon receipt, store it immediately at -20 to -70 °C.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

SEC-MALS View Larger

Recombinant Human TNF-alpha (Catalog # 210-TA) has a molecular weight (MW) of 53.1 kDa as analyzed by SEC-MALS, suggesting that this protein is a homotrimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).

Bioactivity Recombinant Human TNF-alpha Protein Bioactivity View Larger

Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25‑100 pg/mL.

SDS-PAGE Recombinant Human TNF-alpha Protein SDS-PAGE View Larger

1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TNF-alpha

Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (1, 2). Human TNF-alpha consisits of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD) (3). Within the ECD, human TNF-alpha shares 97% aa sequence identity with rhesus and 71%-92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-alpha. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells (1, 2). TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (4). Cell surface TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I (2, 5). Shedding of membrane bound TNF-alpha by TACE/ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (6-8). TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (9, 10) and the hematopoietic cell-restricted 80 kDa TNF RII (11, 12), both of which are also expressed as homotrimers (1, 2, 13). Both type I and type II receptors bind TNF-alpha with comparable affinity (14), although only TNF RI contains a cytoplasmic death domain which triggers the activation of apoptosis. Soluble forms of both types of receptors are released and can neutralize the biological activity of TNF-alpha (15).

References
  1. Zelova, H. and J. Hosek (2013) Inflamm. Res. 62:641.
  2. Juhasz, K. et al. (2013) Expert Rev. Clin. Immunol. 9:335.
  3. Pennica, D. et al. (1984) Nature 312:724.
  4. Tang, P. et al. (1996) Biochemistry 35:8216.
  5. Perez, C. et al. (1990) Cell 63:251.
  6. Black, R.A. et al. (1997) Nature 385:729.
  7. Moss, M.L. et al. (1997) Nature 385:733.
  8. Gearing, A.J.H. et al. (1994) Nature 370:555.
  9. Schall, T.J. et al. (1990) Cell 61:361.
  10. Loetscher, H. et al. (1990) Cell 61:351.
  11. Dembic, Z. et al. (1990) Cytokine 2:231.
  12. Smith, C.A. et al. (1990) Science 248:1019.
  13. Loetscher, H. et al. (1991) J. Biol. Chem. 266:18324.
  14. Pinckard, J.K. et al. (1997) J. Biol. Chem. 272:10784.
  15. Engelmann, H. et al. (1990) J. Biol. Chem. 265:1531.
Long Name
Tumor Necrosis Factor alpha
Entrez Gene IDs
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 102139631 (Cynomolgus Monkey); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFG1F; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha

Citations for Recombinant Human TNF-alpha Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

817 Citations: Showing 1 - 10
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  1. Salivary Cortisol Detection with a Fully Inkjet-Printed Paper-Based Electrochemical Sensor
    Authors: Zea, M;Ben Halima, H;Villa, R;Nemeir, IA;Zine, N;Errachid, A;Gabriel, G;
    Micromachines
    Species: Human
    Sample Types:
    Applications: Bioassay
  2. A Human Brain-Chip for Modeling Brain Pathologies and Screening Blood-Brain Barrier Crossing Therapeutic Strategies
    Authors: Chim, SM;Howell, K;Kokkosis, A;Zambrowicz, B;Karalis, K;Pavlopoulos, E;
    Pharmaceutics
    Species: N/A
    Sample Types: Chip
    Applications: Bioassay
  3. Plug-and-play protein biosensors using aptamer-regulated in vitro transcription
    Authors: Lee, H;Xie, T;Kang, B;Yu, X;Schaffter, SW;Schulman, R;
    Nature communications
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  4. A Nerve-Fibroblast Axis in Mammalian Lung Fibrosis
    Authors: Ishikawa, G;Peng, X;McGovern, J;Ghincea, A;Woo, S;Okuno, D;Yu, S;Lee, CJ;Liu, A;Saber, T;Hu, B;Sun, Y;Sun, H;Jumaily, KA;Feghali-Bostwick, C;Sumida, TS;Sauler, M;Ryu, C;Herzog, EL;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  5. The Fibrotic Phenotype of Human Precision-Cut Lung Slices Is Maintained after Cryopreservation
    Authors: Marimoutou, M;Patel, V;Kim, JH;Schaible, N;Alvarez, J;Hughes, J;Obermok, M;Rodríguez, CI;Kallarakal, T;Suki, B;Amin, K;Krishnan, R;Behrsing, HP;
    Toxics
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Tuberculosis in otherwise healthy adults with inherited TNF deficiency
    Authors: Arias, AA;Neehus, AL;Ogishi, M;Meynier, V;Krebs, A;Lazarov, T;Lee, AM;Arango-Franco, CA;Yang, R;Orrego, J;Corcini Berndt, M;Rojas, J;Li, H;Rinchai, D;Erazo-Borrás, L;Han, JE;Pillay, B;Ponsin, K;Chaldebas, M;Philippot, Q;Bohlen, J;Rosain, J;Le Voyer, T;Janotte, T;Amarajeeva, K;Soudée, C;Brollo, M;Wiegmann, K;Marquant, Q;Seeleuthner, Y;Lee, D;Lainé, C;Kloos, D;Bailey, R;Bastard, P;Keating, N;Rapaport, F;Khan, T;Moncada-Vélez, M;Carmona, MC;Obando, C;Alvarez, J;Cataño, JC;Martínez-Rosado, LL;Sanchez, JP;Tejada-Giraldo, M;L'Honneur, AS;Agudelo, ML;Perez-Zapata, LJ;Arboleda, DM;Alzate, JF;Cabarcas, F;Zuluaga, A;Pelham, SJ;Ensser, A;Schmidt, M;Velásquez-Lopera, MM;Jouanguy, E;Puel, A;Krönke, M;Ghirardello, S;Borghesi, A;Pahari, S;Boisson, B;Pittaluga, S;Ma, CS;Emile, JF;Notarangelo, LD;Tangye, SG;Marr, N;Lachmann, N;Salvator, H;Schlesinger, LS;Zhang, P;Glickman, MS;Nathan, CF;Geissmann, F;Abel, L;Franco, JL;Bustamante, J;Casanova, JL;Boisson-Dupuis, S;
    Nature
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. EGFR inhibits TNF-?-mediated pathway by phosphorylating TNFR1 at tyrosine 360 and 401
    Authors: Nam, YW;Shin, JH;Kim, S;Hwang, CH;Lee, CS;Hwang, G;Kim, HR;Roe, JS;Song, J;
    Cell death and differentiation
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Select DYRK1A Inhibitors Enhance Both Proliferation and Differentiation in Human Pancreatic Beta Cells
    Authors: Wang, P;Wood, O;Choleva, L;Liu, H;Karakose, E;Lambertini, L;Pillard, A;Wu, V;Garcia-Ocana, A;Scott, DK;Kumar, K;DeVita, RJ;Stewart, AF;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. ICAM-1 nanoclusters regulate hepatic epithelial cell polarity by leukocyte adhesion-independent control of apical actomyosin
    Authors: Cacho-Navas, C;López-Pujante, C;Reglero-Real, N;Colás-Algora, N;Cuervo, A;Conesa, JJ;Barroso, S;de Rivas, G;Ciordia, S;Paradela, A;D'Agostino, G;Manzo, C;Feito, J;Andrés, G;Molina-Jiménez, F;Majano, P;Correas, I;Carazo, JM;Nourshargh, S;Huch, M;Millán, J;
    eLife
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Necroptosis blockade prevents lung injury in severe influenza
    Authors: Gautam, A;Boyd, DF;Nikhar, S;Zhang, T;Siokas, I;Van de Velde, LA;Gaevert, J;Meliopoulos, V;Thapa, B;Rodriguez, DA;Cai, KQ;Yin, C;Schnepf, D;Beer, J;DeAntoneo, C;Williams, RM;Shubina, M;Livingston, B;Zhang, D;Andrake, MD;Lee, S;Boda, R;Duddupudi, AL;Crawford, JC;Vogel, P;Loch, C;Schwemmle, M;Fritz, LC;Schultz-Cherry, S;Green, DR;Cuny, GD;Thomas, PG;Degterev, A;Balachandran, S;
    Nature
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. The proton-sensing receptors TDAG8 and GPR4 are differentially expressed in human and mouse oligodendrocytes: Exploring their role in neuroinflammation and multiple sclerosis
    Authors: Caratis, F;Opie?ka, M;Hausmann, M;Velasco-Estevez, M;Rojek, B;de Vallière, C;Seuwen, K;Rogler, G;Karaszewski, B;Rutkowska, A;
    PloS one
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB dependent IFITM3 expression
    Authors: Munir, M;Embry, A;Doench, JG;Heaton, NS;Wilen, CB;Orchard, RC;
    The Journal of biological chemistry
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Logical design of synthetic cis-regulatory DNA for genetic tracing of cell identities and state changes
    Authors: Company, C;Schmitt, MJ;Dramaretska, Y;Serresi, M;Kertalli, S;Jiang, B;Yin, JA;Aguzzi, A;Barozzi, I;Gargiulo, G;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  14. VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation
    Authors: Kosmider, O;Possémé, C;Templé, M;Corneau, A;Carbone, F;Duroyon, E;Breillat, P;Chirayath, TW;Oules, B;Sohier, P;Luka, M;Gobeaux, C;Lazaro, E;Outh, R;Le Guenno, G;Lifermann, F;Berleur, M;Le Mene, M;Friedrich, C;Lenormand, C;Weitten, T;Guillotin, V;Burroni, B;Boussier, J;Willems, L;Aractingi, S;Dionet, L;Tharaux, PL;Vergier, B;Raynaud, P;Ea, HK;Ménager, M;Duffy, D;Terrier, B;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery
    Authors: Ramos, AD;Liang, YY;Surova, O;Bacanu, S;Gerault, MA;
    Cell Reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. BAFF deficiency aggravated optic nerve crush-induced retinal ganglion cells damage by regulating apoptosis and neuroinflammation via NF-?B-I?B? signaling
    Authors: Lin, J;Deng, W;Liao, J;Ke, D;Cui, L;Zhong, H;Huang, K;Jiang, L;Chen, Q;Xu, F;Tang, F;
    International immunopharmacology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Role of the cAMP-PKA-NF-?B pathway in Mucin1 over-expression in A549 cells during Respiratory syncytial virus infection
    Authors: Jin, Y;Zhang, D;Deng, K;Wu, P;Yang, D;Xie, Z;Qiu, W;Yu, G;
    BMC infectious diseases
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. CircMETTL14(11)S upregulated METTL14 and induced CXCR4 to aggravate endothelial inflammation and atherosclerosis
    Authors: Kang, P;Dong, P;
    International immunopharmacology
    Species: Human
    Sample Types:
    Applications: Cell Culture
  19. Effects of tumor necrosis factor-? and interleukin-1? on human retinal endothelial cells
    Authors: Barros Ferreira, L;Ashander, LM;Ma, Y;Appukuttan, B;Williams, KA;Best, G;Smith, JR;
    Cytokine
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  20. CD40 Ligand-CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy
    Authors: Abu El-Asrar, AM;Nawaz, MI;Ahmad, A;Dillemans, L;Siddiquei, M;Allegaert, E;Gikandi, PW;De Hertogh, G;Opdenakker, G;Struyf, S;
    International journal of molecular sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Genome-wide CRISPR activation screen identifies JADE3 as an antiviral activator of NF-kB
    Authors: Munir, M;Embry, A;Doench, JG;Heaton, NS;Wilen, CB;Orchard, RC;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Establishment of a 96-well transwell system using primary human gut organoids to capture multiple quantitative pathway readouts
    Authors: Wright, CW;Li, N;Shaffer, L;Hill, A;Boyer, N;Alves, SE;Venkataraman, S;Biswas, K;Lieberman, LA;Mohammadi, S;
    Scientific reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Activation-induced shift in nutrient preference and function-specific nutrient dependence in human neutrophils
    Authors: Britt, EC;Qing, X;Votava, JA;Lika, J;Wagner, A;Shen, S;Arp, NL;Khan, H;Schieke, SM;Fletcher, CD;Huttenlocher, A;Fan, J;
    bioRxiv : the preprint server for biology
    Species:  Human
    Sample Types:
    Applications: Cell Culture
  24. Characterization and optimization of variability in a human colonic epithelium culture model
    Authors: Pike, CM;Zwarycz, B;McQueen, BE;Castillo, M;Barron, C;Morowitz, JM;Levi, JA;Phadke, D;Balik-Meisner, M;Mav, D;Shah, R;Glasspoole, DLC;Laetham, R;Thelin, W;Bunger, MK;Boazak, EM;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. MicroRNA-1 protects the endothelium in acute lung injury
    Authors: Korde, A;Haslip, M;Pednekar, P;Khan, A;Chioccioli, M;Mehta, S;Lopez-Giraldez, F;Bermejo, S;Rojas, M;Dela Cruz, C;Matthay, MA;Pober, JS;Pierce, RW;Takyar, SS;
    JCI insight
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Public RNA-seq data-based identification and functional analyses reveal that MXRA5 retains proliferative and migratory abilities of dental pulp stem cells
    Authors: Yoshida, K;Suzuki, S;Yuan, H;Sato, A;Hirata-Tsuchiya, S;Saito, M;Yamada, S;Shiba, H;
    Scientific reports
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  27. Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk
    Authors: Feaver, RE;Bowers, MS;Cole, BK;Hoang, S;Lawson, MJ;Taylor, J;LaMoreaux, BD;Zhao, L;Henke, BR;Johns, BA;Nyborg, AC;Wamhoff, BR;Figler, RA;
    PloS one
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. AAV-Mediated Targeting of the Activin A-ACVR1R206H Signaling in Fibrodysplasia Ossificans Progressiva
    Authors: Yang, YS;Lin, C;Ma, H;Xie, J;Kaplan, FS;Gao, G;Shim, JH;
    Biomolecules
    Species: Human, Transgenic Mouse
    Sample Types: Transduced Whole Cells, Whole Cells
    Applications: Bioassay
  29. TNF? induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier function
    Authors: Twarog, M;Schustak, J;Xu, Y;Coble, M;Dolan, K;Esterberg, R;Huang, Q;Saint-Geniez, M;Bao, Y;
    Scientific reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Repurposing Fc gamma receptor I (Fc?RI, CD64) for site-oriented monoclonal antibody capture: A proof-of-concept study for real-time detection of tumor necrosis factor-alpha (TNF -?)
    Authors: Çapk?n, E;Kutlu, A;Yüce, M;
    Heliyon
    Species: N/A
    Sample Types: Recombinant Protein
    Applications: Bioassay
  31. Acylation of MLKL impacts its function in necroptosis
    Authors: Pradhan, AJ;Chitkara, S;Ramirez, RX;Monje-Galvan, V;Sancak, Y;Atilla-Gokcumen, GE;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Anti-inflammatory effects of Arnica montana (mother tincture and homeopathic dilutions) in various cell models
    Authors: Verre, J;Boisson, M;Paumier, A;Tribolo, S;Boujedaini, N;
    Journal of ethnopharmacology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Plug-and-play protein biosensors using aptamer-regulated in vitro transcription
    Authors: Lee, H;Xie, T;Yu, X;Schaffter, SW;Schulman, R;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  34. Single-cell transcriptomics of human cholesteatoma identifies an activin A-producing osteoclastogenic fibroblast subset inducing bone destruction
    Authors: Shimizu, K;Kikuta, J;Ohta, Y;Uchida, Y;Miyamoto, Y;Morimoto, A;Yari, S;Sato, T;Kamakura, T;Oshima, K;Imai, R;Liu, YC;Okuzaki, D;Hara, T;Motooka, D;Emoto, N;Inohara, H;Ishii, M;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  35. IMT504 protects beta cells against apoptosis and maintains beta cell identity, without modifying proliferation
    Authors: Converti, A;Bianchi, MS;Martinez, MD;Montaner, AD;Lux-Lantos, V;Bonaventura, MM;
    Physiological reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Structural homology screens reveal host-derived poxvirus protein families impacting inflammasome activity
    Authors: Boys, IN;Johnson, AG;Quinlan, MR;Kranzusch, PJ;Elde, NC;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection
    Authors: Xu, D;Jiang, W;Wu, L;Gaudet, RG;Park, ES;Su, M;Cheppali, SK;Cheemarla, NR;Kumar, P;Uchil, PD;Grover, JR;Foxman, EF;Brown, CM;Stansfeld, PJ;Bewersdorf, J;Mothes, W;Karatekin, E;Wilen, CB;MacMicking, JD;
    Nature
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
    Authors: Ma, F;Plazyo, O;Billi, AC;Tsoi, LC;Xing, X;Wasikowski, R;Gharaee-Kermani, M;Hile, G;Jiang, Y;Harms, PW;Xing, E;Kirma, J;Xi, J;Hsu, JE;Sarkar, MK;Chung, Y;Di Domizio, J;Gilliet, M;Ward, NL;Maverakis, E;Klechevsky, E;Voorhees, JJ;Elder, JT;Lee, JH;Kahlenberg, JM;Pellegrini, M;Modlin, RL;Gudjonsson, JE;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Dynamics of Ex Vivo Mesenchymal Stromal Cell Potency under Continuous Perfusion
    Authors: Doshi, A;Erickson, P;Teryek, M;Parekkadan, B;
    International journal of molecular sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Polarized Mechanosensitive Signaling Domains Protect Arterial Endothelial Cells Against Inflammation
    Authors: Hong, SG;Ashby, JW;Kennelly, JP;Wu, M;Chattopadhyay, E;Foreman, R;Tontonoz, P;Turowski, P;Gallagher-Jones, M;Mack, JJ;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro
    Authors: Soldati, S;B�r, A;Vladymyrov, M;Glavin, D;McGrath, JL;Gosselet, F;Nishihara, H;Goelz, S;Engelhardt, B;
    Journal of neuroinflammation
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis
    Authors: Stavre, Z;Kim, JM;Yang, YS;N�ndel, K;Chaugule, S;Sato, T;Park, KH;Gao, G;Gravallese, EM;Shim, JH;
    Proceedings of the National Academy of Sciences of the United States of America
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Altered Functionality of Lipoprotein(a) Impacts on Angiogenesis in Diabetic Retinopathy
    Authors: Shariatzadeh, M;Nagtzaam, NMA;van Vark-van der Zee, L;van Holten-Neelen, C;Verhoeven, AJM;Dehairs, J;Swinnen, JV;Leijten, F;Ten Berge, JC;Ciriano, JPM;Wong, KT;Mulder, M;Leenen, PJM;Dik, WA;
    Investigative ophthalmology & visual science
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Lipid-Independent Regulation of PLIN5 via IL-6 through the JAK/STAT3 Axis in Hep3B Cells
    Authors: M Krizanac, PB Mass Sanch, SK Schröder, R Weiskirche, A Asimakopou
    International Journal of Molecular Sciences, 2023-04-13;24(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8+ T cells in HIV infection
    Authors: MP Cabral-Pic, L Papagno, X Lahaye, F Perdomo-Ce, S Volant, E White, V Monceaux, S Llewellyn-, R Fromentin, DA Price, N Chomont, N Manel, A Saez-Cirio, V Appay
    EBioMedicine, 2023-04-12;91(0):104557.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Anti-inflammatory properties of antiangiogenic fucoidan in retinal pigment epithelium cells
    Authors: P Dörschmann, C Seeba, T Thalenhors, J Roider, A Klettner
    Heliyon, 2023-04-10;9(4):e15202.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Cell Culture
  47. Pomegranate Extract Affects Gut Biofilm Forming Bacteria and Promotes Intestinal Mucosal Healing Regulating the Crosstalk between Epithelial Cells and Intestinal Fibroblasts
    Authors: G Rizzo, SE Pineda Cha, E Vandenkoor, CL Cárdenas R, V Cento, V Garlatti, M Wozny, G Sammarco, A Di Claudio, L Meanti, S Elangovan, A Romano, G Roda, L Loy, A Dal Buono, R Gabbiadini, S Lovisa, R Rusconi, A Repici, A Armuzzi, S Vetrano
    Nutrients, 2023-04-05;15(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Structural homology screens reveal poxvirus-encoded proteins impacting inflammasome-mediated defenses
    Authors: IN Boys, AG Johnson, M Quinlan, PJ Kranzusch, NC Elde
    bioRxiv : the preprint server for biology, 2023-04-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. SARS-CoV-2 ORF3a positively regulates NF-kappaB activity by enhancing IKKbeta-NEMO interaction
    Authors: Y Nie, L Mou, Q Long, D Deng, R Hu, J Cheng, J Wu
    Virus research, 2023-03-13;328(0):199086.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Activation of Endothelial Large Conductance Potassium Channels Protects against TNF-alpha-Induced Inflammation
    Authors: T Zyrianova, K Zou, B Lopez, A Liao, C Gu, R Olcese, A Schwingsha
    International Journal of Molecular Sciences, 2023-02-17;24(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells
    Authors: F Parween, SP Singh, HH Zhang, N Kathuria, FA Otaizo-Car, A Shamsaddin, PJ Gardina, S Ganesan, J Kabat, HA Lorenzi, TG Myers, JM Farber
    bioRxiv : the preprint server for biology, 2023-02-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation
    Authors: DI Cho, MJ Ahn, HH Cho, M Cho, JH Jun, BG Kang, SY Lim, SJ Yoo, MR Kim, HS Kim, SJ Lee, LT Dat, C Lee, YS Kim, Y Ahn
    Experimental & Molecular Medicine, 2023-02-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis
    Authors: J Nassour, LG Aguiar, A Correia, TT Schmidt, L Mainz, S Przetocka, C Haggblom, N Tadepalle, A Williams, MN Shokhirev, SC Akincilar, V Tergaonkar, GS Shadel, J Karlseder
    Nature, 2023-02-08;614(7949):767-773.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. TGF-Beta Induces Activin A Production in Dermal Fibroblasts Derived from Patients with Fibrodysplasia Ossificans Progressiva
    Authors: RD de Ruiter, LE Wisse, T Schoenmake, M Yaqub, G Sánchez-Du, EMW Eekhoff, D Micha
    International Journal of Molecular Sciences, 2023-01-24;24(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Fructose-1,6-bisphosphatase 1 dephosphorylates IkappaBalpha and suppresses colorectal tumorigenesis
    Authors: W Zhu, H Chu, Y Zhang, T Luo, H Yu, H Zhu, Y Liu, H Gao, Y Zhao, Q Li, X Wang, G Li, W Yang
    Cell Research, 2023-01-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Anti-inflammatory properties of antiangiogenic fucoidan in retinal pigment epithelium cells
    Authors: P Dörschmann, C Seeba, T Thalenhors, J Roider, A Klettner
    Heliyon, 2023;9(4):e15202.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Cell Culture
  57. NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes
    Authors: DR Calabrese, T Tsao, M Magnen, C Valet, Y Gao, B Mallavia, JJ Tian, EA Aminian, KM Wang, A Shemesh, EB Punzalan, A Sarma, CS Calfee, SA Christenso, CR Langelier, SR Hays, JA Golden, LE Leard, ME Kleinhenz, NA Kolaitis, RJ Shah, A Venado, LL Lanier, JR Greenland, DM Sayah, A Ardehali, J Kukreja, SS Weigt, JA Belperio, JP Singer, MR Looney
    JCI Insight, 2022-12-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. A Novel Cortisol Immunosensor Based on a Hafnium Oxide/Silicon Structure for Heart Failure Diagnosis
    Authors: H Ben Halima, N Zine, J Bausells, N Jaffrezic-, A Errachid
    Micromachines, 2022-12-16;13(12):.
    Species: Human
    Sample Types: Recombinanat Protein
    Applications: Bioassay
  59. Intestinal epithelial BLT1 promotes mucosal repair
    Authors: S Hayashi, CK Muraleedha, M Oku, S Tomar, SP Hogan, M Quiros, CA Parkos, A Nusrat
    JCI Insight, 2022-12-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Blood serum analysis: A modified sandwich enzyme-linked immunosorbent assay protocol
    Authors: D Cai, M Fraunfelde, SY Chen
    MethodsX, 2022-11-22;9(0):101923.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Control
  61. Dienogest May Reduce Estradiol- and Inflammatory Cytokine-Induced Cell Viability and Proliferation and Inhibit the Pathogenesis of Endometriosis: A Cell Culture- and Mouse Model-Based Study
    Authors: HJ Kim, SH Kim, YS Oh, SR Lee, HD Chae
    Biomedicines, 2022-11-21;10(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  62. Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on human inflammatory osteoarthritis models
    Authors: K Li, Y Zhu, P Zhang, M Alini, S Grad, Z Li
    Journal of Orthopaedic Translation, 2022-10-29;38(0):106-116.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  63. In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells
    Authors: B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang
    Cells, 2022-10-28;11(21):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Targeting hypoxia-induced tumor stemness by activating pathogen-induced stem cell niche defense.
    Authors: Bhuyan S, Pal B, Pathak L, Saikia P, Mitra S, Gayan S, Mokhtari R, Li H, Ramana C, Baishya D, Das B
    Front Immunol, 2022-09-29;13(0):933329.
    Species: Complex Species Category
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease
    Authors: P Pavlidis, A Tsakmaki, A Treveil, K Li, D Cozzetto, F Yang, U Niazi, BH Hayee, M Saqi, J Friedman, T Korcsmaros, G Bewick, N Powell
    Cell Reports, 2022-09-27;40(13):111439.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  66. Delayed regression of laser-induced choroidal neovascularization in TNFalpha-null mice
    Authors: H Iwanishi, O Yamanaka, T Sumioka, S Yasuda, M Miyajima, S Saika
    Journal of Cellular and Molecular Medicine, 2022-09-20;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Improved immunoassay sensitivity and specificity using single-molecule colocalization
    Authors: AA Hariri, SS Newman, S Tan, D Mamerow, AM Adams, N Maganzini, BL Zhong, M Eisenstein, AR Dunn, HT Soh
    Nature Communications, 2022-09-12;13(1):5359.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  68. DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells
    Authors: YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra
    Science Advances, 2022-08-24;8(34):eabn5522.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. STUB1 is an intracellular checkpoint for interferon gamma sensing
    Authors: S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge
    Scientific Reports, 2022-08-18;12(1):14087.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Dermatopontin Influences the Development of Obesity-Associated Colon Cancer by Changes in the Expression of Extracellular Matrix Proteins
    Authors: V Catalán, P Domench, J Gómez-Ambr, B Ramírez, S Becerril, A Mentxaka, A Rodríguez, V Valentí, R Moncada, J Baixauli, C Silva, J Escalada, G Frühbeck
    International Journal of Molecular Sciences, 2022-08-17;23(16):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Stimulation
  71. Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation
    Authors: DC Humphries, R Mills, C Boz, BJ McHugh, N Hirani, AG Rossi, A Pedersen, HT Schambye, RJ Slack, H Leffler, UJ Nilsson, W Wang, T Sethi, AC Mackinnon
    Frontiers in Pharmacology, 2022-08-08;13(0):949264.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Ralpha
    Authors: Z Cai, S Tian, T Klein, L Tu, LW Geenen, T Koudstaal, AE van den Bo, YB de Rijke, IKM Reiss, E Boersma, C van der Le, M Van Faasse, I Kema, DJ Duncker, KA Boomars, K Tran-Lundm, C Guignabert, D Merkus
    Scientific Reports, 2022-07-19;12(1):12326.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. In vitro assessment of the anti-inflammatory and skin-moisturizing effects of Filipendula palmata (Pall.) Maxim. On human keratinocytes and identification of its bioactive phytochemicals
    Authors: XJ Mi, JK Kim, S Lee, SK Moon, YJ Kim, H Kim
    Journal of ethnopharmacology, 2022-07-07;296(0):115523.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
    Authors: MD Gundersen, KB Larsen, KM Johnsen, R Goll, J Florholmen, G Haraldsen
    Scientific Reports, 2022-07-07;12(1):11550.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  75. Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4
    Authors: S Wang, B Li, V Solomon, A Fonteh, SI Rapoport, DA Bennett, Z Arvanitaki, HC Chui, PM Sullivan, HN Yassine
    Molecular Neurodegeneration, 2022-06-15;17(1):42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
    Authors: E Iverson, K Griswold, D Song, TB Gagliardi, K Hamidzadeh, M Kesimer, S Sinha, M Perry, GA Duncan, MA Scull
    MBio, 2022-06-14;0(0):e0105522.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells
    Authors: S Hong, EY Kim, SE Lim, JH Kim, Y Sohn, HS Jung
    International Journal of Molecular Sciences, 2022-04-18;23(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Secreted NF-kappaB suppressive microbial metabolites modulate gut inflammation
    Authors: R Giri, EC Hoedt, S Khushi, AA Salim, AS Bergot, V Schreiber, R Thomas, MA McGuckin, TH Florin, M Morrison, RJ Capon, P Ó Cuív, J Begun
    Cell Reports, 2022-04-12;39(2):110646.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Effect of probiotic Lactobacillus paracasei on tumor necrosis factor-alpha level in gingival crevicular fluid of patients undergoing impacted third molar removal
    Authors: S Banjonjit, M Taweechoti, S Rungsiyano
    Journal of oral science, 2022-04-08;0(0):.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA Standard
  80. The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells
    Authors: P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes
    Cancers, 2022-03-11;14(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  81. Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus
    Authors: D Stacey, L Chen, PJ Stanczyk, JMM Howson, AM Mason, S Burgess, S MacDonald, J Langdown, H McKinney, K Downes, N Farahi, JE Peters, S Basu, JS Pankow, W Tang, N Pankratz, M Sabater-Ll, PS de Vries, NL Smith, CHARGE Hem, AD Gelinas, DJ Schneider, N Janjic, NJ Samani, S Ye, C Summers, ER Chilvers, J Danesh, DS Paul
    Nature Communications, 2022-03-09;13(1):1222.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Synoviocytes from pigmented villonodular synovitis are less sensitive to cadmium-induced cell death than synoviocytes from rheumatoid arthritis.
    Authors: H Farese, Farese H, M Noack, Noack M, P Miossec
    Sci Rep, 2022-03-09;12(1):3832.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  83. Administration of probiotics to healthy volunteers: effects on reactivity of intestinal mucosa and systemic leukocytes
    Authors: C Stene, A Röme, I Palmquist, C Linninge, G Molin, S Ahrné, LB Johnson, B Jeppsson
    BMC gastroenterology, 2022-03-05;22(1):100.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Cell Culture
  84. 5,8-Dihydroxy-4 ', 7-dimethoxyflavone Attenuates TNF-alpha-Induced Expression of Vascular Cell Adhesion Molecule-1 through EGFR/PKCalpha/PI3K/Akt/Sp1-Dependent Induction of Heme Oxygenase-1 in Human Cardiac Fibroblasts
    Authors: CC Yang, LD Hsiao, YF Shih, HH Lin, CM Yang
    Oxidative Medicine and Cellular Longevity, 2022-03-04;2022(0):1372958.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Mulberrin confers protection against hepatic fibrosis by Trim31/Nrf2 signaling
    Authors: C Ge, J Tan, D Lou, L Zhu, Z Zhong, X Dai, Y Sun, Q Kuang, J Zhao, L Wang, J Liu, B Wang, M Xu
    Redox Biology, 2022-02-24;51(0):102274.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. MG132 Induces Progerin Clearance and Improves Disease Phenotypes in HGPS-like Patients' Cells
    Authors: K Harhouri, P Cau, F Casey, KM Guedenon, Y Doubaj, L Van Malder, G Mejia-Balt, C Bartoli, A De Sandre-, N Lévy
    Cells, 2022-02-10;11(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation
    Authors: MA Shandell, AL Capatina, SM Lawrence, WJ Brackenbur, D Lagos
    The Journal of Biological Chemistry, 2022-02-09;0(0):101707.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Soluble PD-L1 through alternative polyadenylation works as a decoy in lung cancer immunotherapy
    Authors: R Sagawa, S Sakata, B Gong, Y Seto, A Takemoto, S Takagi, H Ninomiya, N Yanagitani, M Nakao, M Mun, K Uchibori, M Nishio, Y Miyazaki, Y Shiraishi, S Ogawa, K Kataoka, N Fujita, K Takeuchi, R Katayama
    JCI Insight, 2022-01-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Tissue Inhibitor of Metalloproteinase-3 Ameliorates Diabetes-Induced Retinal Inflammation
    Authors: AM Abu El-Asr, A Ahmad, MI Nawaz, MM Siddiquei, A De Zutter, L Vanbrabant, PW Gikandi, G Opdenakker, S Struyf
    Frontiers in Physiology, 2022-01-10;12(0):807747.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Immune regulator LGP2 targets Ubc13/UBE2N to mediate widespread interference with K63 polyubiquitination and NF-kappaB activation
    Authors: JJ Lenoir, JP Parisien, CM Horvath
    Cell Reports, 2021-12-28;37(13):110175.
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  91. Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1
    Authors: Y Hu, H Zhang, N Xie, D Liu, Y Jiang, Z Liu, D Ye, S Liu, X Chen, C Li, Q Wang, X Huang, Y Liu, Y Shi, X Zhang
    Cell Death and Differentiation, 2021-12-01;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  92. CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction
    Authors: L Toma, T Barb?lat?, GM Sanda, LS Niculescu, AV Sima, CS Stancu
    Biomolecules, 2021-11-25;11(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
    Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
    Cell Reports, 2021-11-23;37(8):110037.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  94. Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells
    Authors: CW Lee, YF Chen, AW Hsiao, AY Wang, OY Shen, BY Wang, LWC Ho, WT Lin, CHJ Choi, OK Lee
    Journal of advanced research, 2021-11-19;39(0):73-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling
    Authors: C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen
    The Journal of Biological Chemistry, 2021-11-03;0(0):101380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. The Activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients
    Authors: M McAleavy, Q Zhang, PJ Ehmann, J Xu, MF Wipperman, D Ajithdoss, L Pan, M Wakai, R Simonson, A Gadi, A Oyejide, SC Hamon, A Boyapati, LG Morton, T Shavlakadz, CA Kyratsous, DJ Glass
    Molecular and Cellular Biology, 2021-11-01;0(0):MCB0046721.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Novel cytoplasmic lncRNA IKBKBAS promotes lung adenocarcinoma metastasis by upregulating IKKbeta and consequential activation of NF-kappaB signaling pathway
    Authors: Y Xing, Y Lin, Y Zhang, J Hu, J Liu, Y Tian, J Zhao, W Chen, B Han
    Cell Death & Disease, 2021-10-26;12(11):1004.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Diverse inflammatory threats modulate astrocytes Ca2+ signaling via connexin43 hemichannels in organotypic spinal slices
    Authors: G Panattoni, R Amoriello, C Memo, A Thalhammer, C Ballerini, L Ballerini
    Molecular Brain, 2021-10-25;14(1):159.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  99. Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris
    Authors: S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, MK Sarkar, O Plazyo, AC Billi, R Wasikowski, KM Smith, P Honore, VE Scott, E Maverakis, JM Kahlenberg, G Wang, NL Ward, PW Harms, JE Gudjonsson
    JCI Insight, 2021-10-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells
    Authors: VA Samara, S Das, MA Reddy, VS Tanwar, K Stapleton, A Leung, M Abdollahi, R Ganguly, L Lanting, R Natarajan
    Cells, 2021-10-09;10(10):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  101. Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKbeta promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice
    Authors: I Papazian, E Tsoukala, A Boutou, M Karamita, K Kambas, L Iliopoulou, R Fischer, RE Kontermann, MC Denis, G Kollias, H Lassmann, L Probert
    Journal of Neuroinflammation, 2021-09-26;18(1):222.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. TNF-alpha Increases IP-10 Expression in MCF-7 Breast Cancer Cells via Activation of the JNK/c-Jun Pathways
    Authors: S Kochumon, A Al-Sayyar, T Jacob, A Hasan, F Al-Mulla, S Sindhu, R Ahmad
    Biomolecules, 2021-09-13;11(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Correction: Monocyte subset redistribution from blood to kidneys in patients with Puumala virus caused hemorrhagic fever with renal syndrome
    Authors: S Vangeti, T Strandin, S Liu, J Tauriainen, A Räisänen-S, LE Cabrera, A Hassinen, S Mäkelä, J Mustonen, A Vaheri, O Vapalahti, J Klingström, A Smed-Sören
    PloS Pathogens, 2021-08-25;17(8):e1009876.
    Species: Human
    Sample Types:
    Applications: Bioassay
  104. Pro-inflammatory beta cell small extracellular vesicles induce beta cell failure through activation of the CXCL10/CXCR3 axis in diabetes
    Authors: N Javeed, TK Her, MR Brown, P Vanderboom, K Rakshit, AM Egan, A Vella, I Lanza, AV Matveyenko
    Cell Reports, 2021-08-24;36(8):109613.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  105. Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96?Transwell air-liquid interface model
    Authors: T Bluhmki, S Traub, AK Müller, S Bitzer, E Schruf, MT Bammert, M Leist, F Gantner, JP Garnett, R Heilker
    Scientific Reports, 2021-08-23;11(1):17028.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis
    Authors: R Biavasco, E Lettera, K Giannetti, D Gilioli, S Beretta, A Conti, S Scala, D Cesana, P Gallina, M Norelli, L Basso-Ricc, A Bondanza, G Cavalli, M Ponzoni, L Dagna, C Doglioni, A Aiuti, I Merelli, R Di Micco, E Montini
    Nature Communications, 2021-07-27;12(1):4559.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis
    Authors: S Honda, K Ikeda, R Urata, E Yamazaki, N Emoto, S Matoba
    Scientific Reports, 2021-07-16;11(1):14608.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. MicroRNA-378a-3p is overexpressed in psoriasis and modulates cell cycle arrest in keratinocytes via targeting BMP2 gene
    Authors: W Soonthornc, P Tangtanata, K Meesilpavi, V Dalm, P Kueanjinda, J Wongpiyabo
    Scientific Reports, 2021-07-09;11(1):14186.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Protective effects of the knockdown of lncRNA AK139328 against oxygen glucose deprivation/reoxygenation-induced injury in PC12 cells
    Authors: L Liu, B Zheng, Z Wang
    Molecular Medicine Reports, 2021-07-02;24(3):.
    Species: Rat
    Sample Types: Cell Culture Supernates
  110. CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy
    Authors: AM Abu El-Asr, MI Nawaz, A Ahmad, MM Siddiquei, E Allegaert, PW Gikandi, G De Hertogh, G Opdenakker
    Investigative Ophthalmology & Visual Science, 2021-07-01;62(9):32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Transdifferentiation of Human Fibroblasts into Skeletal Muscle Cells: Optimization and Assembly into Engineered Tissue Constructs through Biological Ligands
    Authors: KMA Abdel-Raou, R Rezgui, C Stefanini, JCM Teo, N Christofor
    Biology, 2021-06-16;10(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis
    Authors: K Andelid, K Öst, A Andersson, E Mohamed, Z Jevnikar, LEGW Vanfletere, M Göransson
    Respiratory Research, 2021-06-07;22(1):172.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8
    Authors: N Tamassia, F Bianchetto, S Gasperini, S Polletti, E Gardiman, R Ostuni, G Natoli, MA Cassatella
    Cell Reports, 2021-05-18;35(7):109143.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells
    Authors: S Yan, Q Li, D Zhang, X Wang, Y Xu, C Zhang, D Guo, Y Bao
    American journal of cancer research, 2021-05-15;11(5):2062-2080.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
    Authors: M Zelic, F Pontarelli, L Woodworth, C Zhu, A Mahan, Y Ren, M LaMorte, R Gruber, A Keane, P Loring, L Guo, TH Xia, B Zhang, P Orning, E Lien, A Degterev, T Hammond, D Ofengeim
    Cell Reports, 2021-05-11;35(6):109112.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB
    Authors: B Galinski, M Luxemburg, Y Landesman, B Pawel, KJ Johnson, SR Master, KW Freeman, DM Loeb, JM Hébert, DA Weiser
    Translational Oncology, 2021-05-09;14(8):101114.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4
    Authors: S Wang, B Li, V Solomon, A Fonteh, SI Rapoport, DA Bennett, Z Arvanitaki, HC Chui, C Miller, PM Sullivan, HY Wang, HN Yassine
    Molecular Neurodegeneration, 2021-04-16;16(1):26.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell-Derived RPE
    Authors: SR Sripathi, MW Hu, MM Liu, J Wan, J Cheng, Y Duan, JL Mertz, KJ Wahlin, J Maruotti, CA Berlinicke, J Qian, DJ Zack
    Investigative Ophthalmology & Visual Science, 2021-04-01;62(4):1.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure
    Authors: P Rueda, J Merlin, S Chimenti, M Feletou, J Paysant, PJ White, A Christopou, PM Sexton, RJ Summers, WN Charman, LT May, CJ Langmead
    Frontiers in Pharmacology, 2021-03-11;12(0):628060.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  120. LL-37-mediated activation of host receptors is critical for defense against group A streptococcal infection
    Authors: D Biswas, P Ambalavana, M Ravins, A Anand, A Sharma, KXZ Lim, RYM Tan, HY Lim, A Sol, G Bachrach, V Angeli, E Hanski
    Cell Reports, 2021-03-02;34(9):108766.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm
    Authors: P Gao, P Gao, J Zhao, S Shan, W Luo, OJ Slivano, W Zhang, A Tabuchi, SA LeMaire, L Maegdefess, YH Shen, JM Miano, HA Singer, X Long
    Redox Biology, 2021-02-20;41(0):101903.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer
    Authors: J Cai, D Hu, J Sakya, T Sun, D Wang, L Wang, X Mao, Z Su
    Cell Death & Disease, 2021-02-01;12(2):140.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. The inflammatory kinase IKK&alpha phosphorylates and stabilizes c-Myc and enhances its activity
    Authors: B Moser, B Hochreiter, J Basílio, V Gleitsmann, A Panhuber, A Pardo-Garc, B Hoesel, M Salzmann, U Resch, M Noreen, JA Schmid
    Molecular Cancer, 2021-01-18;20(1):16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes
    Authors: TM Garcia-Bat, ML Palma, RR Anderko, DC Hsu, J Ananworani, BT Korber, GD Gaiha, N Phanuphak, R Thomas, S Tovanabutr, BD Walker, JW Mellors, PA Piazza, E Kroon, SA Riddler, NL Michael, CR Rinaldo, RB Mailliard, I4C and RV
    EBioMedicine, 2021-01-12;63(0):103175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Vascular endothelial ERp72 is involved in the inflammatory response in a rat model of skeletal muscle injury
    Authors: NB Khalaf, D Al-?ehatab, DM Fathallah
    Molecular Medicine Reports, 2021-01-05;23(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
    Authors: J Stebbing, G Sánchez Ni, M Falcone, S Youhanna, P Richardson, S Ottaviani, JX Shen, C Sommerauer, G Tiseo, L Ghiadoni, A Virdis, F Monzani, LR Rizos, F Forfori, A Avendaño-C, S De Marco, L Carrozzi, F Lena, PM Sánchez-Ju, LG Lacerenza, N Cesira, D Caldevilla, A Perrella, L Niccoli, LS Méndez, D Matarrese, D Goletti, YJ Tan, V Monteil, G Dranitsari, F Cantini, A Farcomeni, S Dutta, SK Burley, H Zhang, M Pistello, W Li, M Mas Romero, F Andrés Pre, RS Simón-Tale, R García-Mol, C Kutter, JH Felce, ZF Nizami, AG Miklosi, JM Penninger, F Menichetti, A Mirazimi, P Abizanda, VM Lauschke
    Sci Adv, 2021-01-01;0(0):.
    Species: Human
    Sample Types: Spheroid
    Applications: Spheroid Culture
  127. Acadesine suppresses TNF-&alpha induced complement component 3 (C3), in retinal pigment epithelial (RPE) cells
    Authors: NE Efstathiou, GA Moustafa, DE Maidana, EK Konstantin, S Notomi, PRT Barbisan, CD Georgakopo, JW Miller, DG Vavvas
    PLoS ONE, 2020-12-23;15(12):e0244307.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Fluorofenidone Alleviates Renal Fibrosis by Inhibiting Necroptosis Through RIPK3/MLKL Pathway
    Authors: Q Dai, Y Zhang, X Liao, Y Jiang, X Lv, X Yuan, J Meng, Y Xie, Z Peng, Q Yuan, L Tao, L Huang
    Frontiers in Pharmacology, 2020-12-16;11(0):534775.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  129. Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
    Authors: A Dorronsoro, V Lang, I Ferrin, J Fernández-, L Zabaleta, E Pérez-Ruiz, P Sepúlveda, C Trigueros
    Scientific Reports, 2020-12-14;10(1):21853.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
    Authors: V Simion, H Zhou, S Haemmig, JB Pierce, S Mendes, Y Tesmenitsk, D Pérez-Crem, JF Lee, AF Chen, N Ronda, B Papotti, JA Marto, MW Feinberg
    Nature Communications, 2020-12-01;11(1):6135.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  131. Red-COLA1: a human fibroblast reporter cell line for type I collagen transcription
    Authors: HH Wong, SH Seet, CC Bascom, RJ Isfort, F Bard
    Sci Rep, 2020-11-12;10(1):19723.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  132. CD4 T-cell immune stimulation of HER2?+?breast cancer cells alters response to trastuzumab in vitro
    Authors: PN Song, A Mansur, KJ Dugger, TR Davis, G Howard, TE Yankeelov, AG Sorace
    Cancer Cell International, 2020-11-10;20(1):544.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. &beta-Catenin Regulates Wound Healing and IL-6 Expression in Activated Human Astrocytes
    Authors: VV Edara, S Nooka, J Proulx, S Stacy, A Ghorpade, K Borgmann
    Biomedicines, 2020-11-06;8(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  134. Relative Deficiency of Anti-Inflammatory N-Acylethanolamines Compared to Prostaglandins in Oral Lichen Planus
    Authors: L Rankin, S Gouveia-Fi, KP Danielsson, CJ Fowler
    Biomedicines, 2020-11-06;8(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  135. Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs
    Authors: S Paliwal, A de Giorgio, D Neil, JB Michel, AM Lacoste
    Sci Rep, 2020-10-26;10(1):18250.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  136. The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
    Authors: K Landgraf, N Klöting, M Gericke, N Maixner, E Guiu-Jurad, M Scholz, AV Witte, F Beyer, JT Schwartze, M Lacher, A Villringer, P Kovacs, A Rudich, M Blüher, W Kiess, A Körner
    Cell Rep, 2020-10-20;33(3):108295.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1
    Authors: F Al-Rashed, R Thomas, A Al-Roub, F Al-Mulla, R Ahmad
    Molecules, 2020-10-14;25(20):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia
    Authors: S Nagel, C Pommerenke, C Meyer, RAF MacLeod, HG Drexler
    PLoS ONE, 2020-10-13;15(10):e0240120.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  139. Stearic Acid and TNF-&alpha Co-Operatively Potentiate MIP-1&alpha Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway
    Authors: S Kochumon, H Arefanian, R Azim, S Shenouda, T Jacob, N Abu Khalaf, F Al-Rashed, A Hasan, S Sindhu, F Al-Mulla, R Ahmad
    Biomedicines, 2020-10-09;8(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation
    Authors: EM Wilfong, R Croze, X Fang, M Schwede, E Niemi, GY López, JW Lee, MC Nakamura, MA Matthay
    PLoS ONE, 2020-10-06;15(10):e0240319.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  141. CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis
    Authors: S Panigrahi, B Chen, M Fang, D Potashniko, AA Komissarov, A Lebedeva, GM Michaelson, JM Wyrick, SR Morris, SF Sieg, M Paiardini, FJ Villinger, K Harth, VS Kashyap, MJ Cameron, CM Cameron, E Vasilieva, L Margolis, SA Younes, NT Funderburg, DA Zidar, MM Lederman, ML Freeman
    PLoS Pathog, 2020-09-25;16(9):e1008885.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  142. Association of tricellulin expression with poor colorectal cancer prognosis and metastasis
    Authors: JX Zhang, MB Qin, Z Ye, P Peng, SM Li, Q Song, L Lin, SQ Liu, LH Xie, Y Zhu, JA Huang
    Oncology reports, 2020-09-17;44(5):2174-2184.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  143. Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia
    Authors: S Kim, M Park, JY Kim, T Kim, JY Hwang, KS Ha, MH Won, S Ryoo, YG Kwon, YM Kim
    Cells, 2020-08-31;9(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. The Expressions of TSLP, IL-33, and IL-17A in Monocyte Derived Dendritic Cells from Asthma and COPD Patients are Related to Epithelial-Macrophage Interactions
    Authors: M Paplinska-, P Misiukiewi, M Proboszcz, P Nejman-Gry, K Gorska, R Krenke
    Cells, 2020-08-22;9(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  145. Development of a miniaturized 96-Transwell air-liquid interface human small airway epithelial model
    Authors: T Bluhmki, S Bitzer, JA Gindele, E Schruf, T Kiechle, M Webster, J Schymeinsk, R Ries, F Gantner, D Bischoff, J Garnett, R Heilker
    Sci Rep, 2020-08-03;10(1):13022.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. MIP-1alpha Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-alpha Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
    Authors: S Sindhu, N Akhter, A Wilson, R Thomas, H Arefanian, A Al Madhoun, F Al-Mulla, R Ahmad
    Cells, 2020-07-29;9(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications
    Authors: D Jian, Y Wang, L Jian, H Tang, L Rao, K Chen, Z Jia, W Zhang, Y Liu, X Chen, X Shen, C Gao, S Wang, M Li
    Theranostics, 2020-07-11;10(20):8939-8956.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke
    Authors: BH Clausen, M Wirenfeldt, SS Høgedal, LH Frich, HH Nielsen, HD Schrøder, K Østergaard, B Finsen, BW Kristensen, KL Lambertsen
    Acta Neuropathol Commun, 2020-06-05;8(1):81.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  149. Group V secreted phospholipase A2 plays a protective role against aortic dissection
    Authors: K Watanabe, Y Taketomi, Y Miki, K Kugiyama, M Murakami
    J. Biol. Chem., 2020-06-01;295(30):10092-10111.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  150. Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES)
    Authors: MY Hsieh, JJ Lin, SH Hsia, JL Huang, KW Yeh, KW Chang, WI Lee
    Biomed J, 2020-05-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Tumor necrosis factor-&alpha regulates skeletal myogenesis by inhibiting SP1 interaction with cis-acting regulatory elements within the Fbxl2 gene promoter
    Authors: ME O'Brien, J Londino, M McGinnis, N Weathingto, J Adair, T Suber, V Kagan, K Chen, C Zou, B Chen, J Bon, RK Mallampall
    Mol. Cell. Biol., 2020-05-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  152. Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex
    Authors: J Seo, D Seong, YW Nam, CH Hwang, SR Lee, CS Lee, Y Jin, HW Lee, DB Oh, P Vandenabee, J Song
    Cell Death Differ., 2020-05-26;0(0):.
    Applications: Cell Culture
  153. Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes
    Authors: MF Abas?yan?k, K Wolfe, H Van Phan, J Lin, B Laxman, SR White, PA Verhoef, GM Mutlu, B Patel, S Tay
    Nat Commun, 2020-05-25;11(1):2607.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study
    Authors: D Sinkeviciu, A Aspberg, Y He, AC Bay-Jensen, P Önnerfjord
    BMC Rheumatol, 2020-05-12;4(0):30.
    Species: Bovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  155. Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins
    Authors: RA Lu, AA Zeki, S Ram-Mohan, N Nguyen, Y Bai, K Chmiel, S Pecic, X Ai, R Krishnan, CC Ghosh
    Front Pharmacol, 2020-05-06;11(0):469.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  156. The Deubiquitinating Enzyme USP20 Regulates the TNFalpha-Induced NF-kappaB Signaling Pathway through Stabilization of p62
    Authors: J Ha, M Kim, D Seo, JS Park, J Lee, J Lee, SH Park
    Int J Mol Sci, 2020-04-28;21(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Synergistic activation of NF-&kappaB by TNFAIP3 (A20) reduction and UBE2L3 (UBCH7) augment that synergistically elevate lupus risk
    Authors: T Kim, SC Bae, C Kang
    Arthritis Res. Ther., 2020-04-25;22(1):93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor &alpha (TNF-&alpha) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-?B) Signaling Pathway
    Authors: X Wu, X Deng, J Wang, Q Li
    Med. Sci. Monit., 2020-04-23;26(0):e919392.
    Species: Human
    Sample Types: Whole Cells
  159. Cellular Importin-&alpha3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection
    Authors: S Thiele, S Stanelle-B, S Beck, NM Kouassi, M Zickler, M Müller, B Tuku, P Resa-Infan, D van Riel, M Alawi, T Günther, F Rother, S Hügel, S Reimering, A McHardy, A Grundhoff, W Brune, A Osterhaus, M Bader, E Hartmann, G Gabriel
    Cell Rep, 2020-04-21;31(3):107549.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations
    Authors: A Nikonova, M Khaitov, DJ Jackson, S Traub, MB Trujillo-T, DA Kudlay, AS Dvornikov, A Del-Rosari, R Valenta, LA Stanciu, R Khaitov, SL Johnston
    EBioMedicine, 2020-04-09;54(0):102734.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  161. Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration
    Authors: Y Wooff, N Fernando, JHC Wong, C Dietrich, R Aggio-Bruc, JA Chu-Tan, AAB Robertson, SL Doyle, SM Man, R Natoli
    Sci Rep, 2020-02-10;10(1):2263.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Monocyte chemoattractant protein?1 promotes the proliferation, migration and differentiation potential of fibroblast?like synoviocytes via the PI3K/P38 cellular signaling pathway
    Authors: X Tong, H Zeng, P Gu, K Wang, H Zhang, X Lin
    Mol Med Rep, 2020-01-29;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  163. Increasing the Medium Osmolarity Reduces the Inflammatory Status of Human OA Chondrocytes and Increases Their Responsiveness to GDF-5
    Authors: T Mang, S Lindemann, A Gigout
    Int J Mol Sci, 2020-01-14;21(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  164. S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma
    Authors: M Tochimoto, Y Oguri, M Hashimura, R Konno, T Matsumoto, A Yokoi, Y Kodera, M Saegusa
    Lab. Invest., 2019-12-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  165. CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome
    Authors: CC Gross, C Meyer, U Bhatia, L Yshii, I Kleffner, J Bauer, AR Tröscher, A Schulte-Me, S Herich, T Schneider-, H Plate, T Kuhlmann, M Schwaninge, W Brück, M Pawlitzki, DA Laplaud, D Loussouarn, J Parratt, M Barnett, ME Buckland, TA Hardy, SW Reddel, M Ringelstei, J Dörr, B Wildemann, M Kraemer, H Lassmann, R Höftberger, E Beltrán, K Dornmair, N Schwab, L Klotz, SG Meuth, G Martin-Blo, H Wiendl, R Liblau
    Nat Commun, 2019-12-18;10(1):5779.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. NF-kappaB-mediated inhibition of microRNA-149-5p regulates Chitinase-3-like 1 expression in human airway epithelial cells
    Authors: K Hübner, D Karwelat, E Pietsch, I Beinborn, S Winterberg, K Bedenbende, BJ Benedikter, B Schmeck, E Vollmeiste
    Cell. Signal., 2019-12-16;67(0):109498.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. The role of endothelial MERTK during the inflammatory response in lungs
    Authors: Y Li, ES Wittchen, E Monaghan-B, C Hahn, HS Earp, CM Doerschuk, K Burridge
    PLoS ONE, 2019-12-05;14(12):e0225051.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model
    Authors: X An, G Liao, Y Chen, A Luo, J Liu, Y Yuan, L Li, L Yang, H Wang, F Liu, G Yang, S Yi, Y Li, J Cheng, Y Lu
    Stem Cell Res Ther, 2019-12-02;10(1):363.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum
    Authors: A Stumpf, T Brandstett, J Hübner, J Rühe
    PLoS ONE, 2019-12-02;14(12):e0225525.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Standard
  170. Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients
    Authors: D Deli?, K Wolk, R Schmid, O Gabrielyan, D Christou, K Rieber, M Rolser, I Jakob, F Wiech, M Griesser, C Wohnhaas, G Kokolakis, E Witte-Händ, P Baum, R Sabat
    J. Dermatol. Sci., 2019-11-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation
    Authors: N Uyama, H Tsutsui, S Wu, K Yasuda, E Hatano, XY Qin, S Kojima, J Fujimoto
    Sci Rep, 2019-11-26;9(1):17558.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  172. Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles
    Authors: B Khiatah, M Qi, W Du, K T-Chen, KM van Megen, RG Perez, JS Isenberg, F Kandeel, BO Roep, HT Ku, IH Al-Abdulla
    Stem Cell Res Ther, 2019-11-15;10(1):322.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  173. Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes
    Authors: J Lin, Y Yu, X Wang, Y Ke, C Sun, L Yue, G Xu, B Xu, L Xu, H Cao, D Xu, N Olsen, W Chen
    J Immunol Res, 2019-11-14;2019(0):6929286.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  174. TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation
    Authors: KA Jha, M Pentecost, R Lenin, J Gentry, L Klaic, N Del Mar, A Reiner, CH Yang, LM Pfeffer, N Sohl, R Gangaraju
    Stem Cell Res Ther, 2019-11-05;10(1):318.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  175. Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE
    Authors: H Wang, E Kunz, GJ Stoddard, WW Hauswirth, ME Hartnett
    Sci Rep, 2019-10-31;9(1):15732.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  176. Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma
    Authors: X Sun, T Hou, E Cheung, TN Iu, VW Tam, IM Chu, MS Tsang, PK Chan, CW Lam, CK Wong
    Cell. Mol. Immunol., 2019-10-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression
    Authors: J Merola, M Reschke, RW Pierce, L Qin, S Spindler, T Baltazar, TD Manes, F Lopez-Gira, G Li, LG Bracaglia, C Xie, N Kirkiles-S, WM Saltzman, GT Tietjen, G Tellides, JS Pober
    JCI Insight, 2019-10-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
    Authors: ER Wonderlich, K Subramania, B Cox, A Wiegand, C Lackman-Sm, MJ Bale, M Stone, R Hoh, MF Kearney, F Maldarelli, SG Deeks, MP Busch, RG Ptak, DA Kulpa
    PLoS Pathog., 2019-10-14;15(10):e1008074.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele
    Authors: H Al-Mossawi, N Yager, CA Taylor, E Lau, S Danielli, J de Wit, J Gilchrist, I Nassiri, EA Mahe, W Lee, L Rizvi, S Makino, J Cheeseman, M Neville, JC Knight, P Bowness, BP Fairfax
    Nat Commun, 2019-10-08;10(1):4575.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Progranulin attenuates liver fibrosis by downregulating the inflammatory response
    Authors: W Yoo, J Lee, KH Noh, S Lee, D Jung, MH Kabir, D Park, C Lee, KS Kwon, JS Kim, S Kim
    Cell Death Dis, 2019-10-07;10(10):758.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress
    Authors: C Merriman, D Fu
    J. Biol. Chem., 2019-10-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma
    Authors: A Shimbo, H Kajiyama, S Tamauchi, N Yoshikawa, Y Ikeda, K Nishino, S Suzuki, K Niimi, J Sakata, F Kikkawa
    Oncol. Rep., 2019-10-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Tissue-regenerative potential of the secretome of gamma-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis
    Authors: E Simader, L Beer, M Laggner, V Vorstandle, A Gugerell, M Erb, P Kalinina, D Copic, D Moser, A Spittler, E Tschachler, H Jan Ankers, M Mildner
    Cell Death Dis, 2019-09-30;10(10):729.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  184. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression
    Authors: J Ren, M Smid, J Iaria, DCF Salvatori, H van Dam, HJ Zhu, JWM Martens, P Ten Dijke
    Breast Cancer Res., 2019-09-18;21(1):109.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
    Authors: NW Zammit, OM Siggs, PE Gray, K Horikawa, DB Langley, SN Walters, SR Daley, C Loetsch, J Warren, JY Yap, D Cultrone, A Russell, EK Malle, JE Villanueva, MJ Cowley, V Gayevskiy, ME Dinger, R Brink, D Zahra, G Chaudhri, G Karupiah, B Whittle, C Roots, E Bertram, M Yamada, Y Jeelall, A Enders, BE Clifton, PD Mabbitt, CJ Jackson, SR Watson, CN Jenne, LL Lanier, T Wiltshire, MH Spitzer, GP Nolan, F Schmitz, A Aderem, BT Porebski, AM Buckle, DW Abbott, JB Ziegler, ME Craig, P Benitez-Ag, J Teo, SG Tangye, C King, M Wong, MP Cox, W Phung, J Tang, W Sandoval, IE Wertz, D Christ, CC Goodnow, ST Grey
    Nat. Immunol., 2019-09-18;20(10):1299-1310.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models
    Authors: JC Chamcheu, S Esnault, VM Adhami, AL Noll, S Banang-Mbe, T Roy, SS Singh, S Huang, KG Kousoulas, H Mukhtar
    Cells, 2019-09-15;8(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. The Possible Role of Neutrophils in the Induction of Osteoclastogenesis
    Authors: CGJ Moonen, TJ de Vries, P Rijkschroe, PE Poubelle, EA Nicu, BG Loos
    J Immunol Res, 2019-09-15;2019(0):8672604.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. An Autocrine Wnt5a Loop Promotes NF-kappaB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma
    Authors: G Barbero, MV Castro, MB Villanueva, MJ Quezada, NB Fernández, S DeMorrow, P Lopez-Berg
    Cells, 2019-09-10;8(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha
    Authors: X Qiu, X Wang, J Qiu, Y Zhu, T Liang, B Gao, Z Wu, C Lian, Y Peng, A Liang, P Su, D Huang
    Stem Cells Int, 2019-09-05;2019(0):6403967.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Effect of Ionizing Radiation on Human EA.hy926 Endothelial Cells under Inflammatory Conditions and Their Interactions with A549 Tumour Cells
    Authors: S Schröder, S Broese, J Baake, D Juer beta, S Kriesen, G Hildebrand, K Manda
    J Immunol Res, 2019-09-02;2019(0):9645481.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  191. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
    Authors: C Jiang, SJ Trudeau, TC Cheong, R Guo, M Teng, LW Wang, Z Wang, C Pighi, C Gautier-Co, Y Ma, S Jiang, C Wang, B Zhao, L Paillard, JG Doench, R Chiarle, BE Gewurz
    Cell Rep, 2019-07-30;28(5):1307-1322.e8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  192. Low concentration flufenamic acid enhances osteogenic differentiation of mesenchymal stem cells and suppresses bone loss by inhibition of the NF-κB signaling pathway
    Authors: X Liu, Z Li, H Liu, Y Zhu, D Xia, S Wang, R Gu, W Wu, P Zhang, Y Liu, Y Zhou
    Stem Cell Res Ther, 2019-07-19;10(1):213.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  193. The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathway
    Authors: Z Ye, L Zhong, S Zhu, Y Wang, J Zheng, S Wang, J Zhang, R Huang
    Cell Death Dis, 2019-07-01;10(7):507.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis
    Authors: LY Wang, XJ Sun, M Chen, MH Zhao
    J Transl Med, 2019-06-11;17(1):197.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  195. Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
    Authors: BD Bryson, TR Rosebrock, FG Tafesse, CY Itoh, A Nibasumba, GH Babunovic, B Corleis, C Martin, C Keegan, P Andrade, S Realegeno, D Kwon, RL Modlin, SM Fortune
    Nat Commun, 2019-05-27;10(1):2329.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses
    Authors: R van Dalen, JS De La Cruz, M Rumpret, FF Fuchsberge, NH van Teijli, J Hanske, C Rademacher, TBH Geijtenbee, JAG van Strijp, C Weidenmaie, A Peschel, DH Kaplan, NM van Sorge
    MBio, 2019-05-14;10(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models
    Authors: N Zhang, DP Heruth, W Wu, LQ Zhang, MN Nsumu, K Shortt, K Li, X Jiang, B Wang, C Friesen, DY Li, SQ Ye
    Cell Biosci, 2019-05-14;9(0):40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  198. Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy
    Authors: SM Ferrari, F Ragusa, SR Paparo, F Nasini, M Nardi, SS Franceschi, P Fallahi, A Antonelli
    Autoimmun Rev, 2019-05-04;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats
    Authors: N Wang, C Luo, H Liu, X Yang, B Hu, W Zhang, B Li, Y Zhu, G Zhu, X Shen, C Peng, Z Shi
    Viruses, 2019-04-24;11(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Xanthatin inhibits STAT3 and NF-?B signalling by covalently binding to JAK and IKK kinases
    Authors: M Liu, CQ Xiao, MW Sun, MJ Tan, LH Hu, Q Yu
    J. Cell. Mol. Med., 2019-04-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Glucocorticoid-dependent expression of IAP participates in the protection against TNF-mediated cytotoxicity in MCF7 cells
    Authors: IB Mitre-Agui, T Barrios-Ga, VM Ruiz-Lopez, AJ Cabrera-Qu, NR Mejia-Domi, JL Ventura-Ga, D Moreno-Mit, A Aranda-Gut, J Mejia-Rang, AR Escalona-G, Y Chavarri-G, A Leon-Del-R, A Zentella-D
    BMC Cancer, 2019-04-15;19(1):356.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis
    Authors: MR Hadjichara, BT Roux, E Csomor, CA Feghali-Bo, LA Murray, DL Clarke, MA Lindsay
    Sci Rep, 2019-04-15;9(1):6020.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Neutrophil GM-CSF receptor dynamics in acute lung injury
    Authors: S De Alessan, GJ Ferguson, AJ Dodd, JK Juss, A Devaprasad, S Piper, O Wyatt, H Killick, DJ Corkill, ES Cohen, A Pandit, TRDJ Radstake, R Simmonds, AM Condliffe, MA Sleeman, AS Cowburn, DK Finch, ER Chilvers
    J. Leukoc. Biol., 2019-04-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1
    Authors: J Kristoff, ML Palma, TM Garcia-Bat, C Shen, N Sluis-Crem, P Gupta, CR Rinaldo, RB Mailliard
    EBioMedicine, 2019-04-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. TGF-?1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM
    Authors: K Wang, S Fang, Q Liu, J Gao, X Wang, H Zhu, Z Zhu, F Ji, J Wu, Y Ma, L Hu, X Shen, D Gao, J Zhu, P Liu, H Zhou
    EBioMedicine, 2019-03-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Synthesis and Biological Evaluation of Fangchinoline Derivatives as Anti-Inflammatory Agents through Inactivation of Inflammasome
    Authors: T Liu, Q Zeng, X Zhao, W Wei, Y Li, H Deng, D Song
    Molecules, 2019-03-23;24(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Physicochemical characterization and phase I study of CMAB008, an infliximab biosimilar produced by a different expression system
    Authors: Q An, Y Zheng, Y Zhao, T Liu, H Guo, D Zhang, W Qian, H Wang, Y Guo, S Hou, J Li
    Drug Des Devel Ther, 2019-03-12;13(0):791-805.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  208. TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma
    Authors: B Podder, C Guttà, J Rožanc, E Gerlach, M Feoktistov, D Panayotova, LG Alexopoulo, M Leverkus, M Rehm
    Cell Death Differ., 2019-03-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
    Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
    Cell Stem Cell, 2019-03-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Cortistatin binds to TNF-? receptors and protects against osteoarthritis
    Authors: Y Zhao, Y Li, R Qu, X Chen, W Wang, C Qiu, B Liu, X Pan, L Liu, K Vasilev, J Hayball, S Dong, W Li
    EBioMedicine, 2019-02-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. A Novel TNF-?-Targeting Aptamer for TNF-?-Mediated Acute Lung Injury and Acute Liver Failure
    Authors: WY Lai, JW Wang, BT Huang, EP Lin, PC Yang
    Theranostics, 2019-02-28;9(6):1741-1751.
    Species: Human
    Sample Types: DNA
    Applications: Bioassay
  212. Trimethylamine N-oxide promotes tissue factor expression and activity in vascular endothelial cells: A new link between trimethylamine N-oxide and atherosclerotic thrombosis
    Authors: X Cheng, X Qiu, Y Liu, C Yuan, X Yang
    Thromb. Res., 2019-02-23;177(0):110-116.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. LncRNA Meg3 protects endothelial function by regulating the DNA damage response
    Authors: MS Shihabudee, X Cheng, M Moran, S Haemmig, MJ Naldrett, S Alvarez, MW Feinberg, X Sun
    Nucleic Acids Res., 2019-02-20;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Extrinsic or Intrinsic Apoptosis by Curcumin and Light: Still a Mystery
    Authors: V Laubach, R Kaufmann, A Bernd, S Kippenberg, N Zöller
    Int J Mol Sci, 2019-02-19;20(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye
    Authors: K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller
    Int J Mol Sci, 2019-02-16;20(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer
    Authors: T Kaprio, T Rasila, J Hagström, H Mustonen, P Lankila, C Haglund, LC Andersson
    PLoS ONE, 2019-02-15;14(2):e0211564.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling
    Authors: Y Wang, Y Liu, M Zhang, L Lv, X Zhang, P Zhang, Y Zhou
    Stem Cell Res Ther, 2019-02-13;10(1):57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis
    Authors: JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic
    J Immunol Res, 2019-02-06;2019(0):1529189.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis
    Authors: BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla
    Sci Rep, 2019-02-04;9(1):1149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate
    Authors: M Bobardt, J Kuo, U Chatterji, S Chanda, SJ Little, N Wiedemann, G Vuagniaux, PA Gallay
    PLoS ONE, 2019-02-04;14(2):e0211746.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Autoimmune rheumatic disease IgG has differential effects upon neutrophil integrin activation that is modulated by the endothelium
    Authors: AA Khawaja, C Pericleous, VM Ripoll, JC Porter, IP Giles
    Sci Rep, 2019-02-04;9(1):1283.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  222. CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
    Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
    Cancer Res., 2019-02-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system
    Authors: S Murakami, R Matsumoto, T Kanamori
    Sci Rep, 2019-01-24;9(1):671.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA (Capture)
  224. Rifamycin SV exhibits strong anti-inflammatory in�vitro activity through pregnane X receptor stimulation and NF?B inhibition
    Authors: C Rosette, FJ Agan, N Rosette, L Moro, A Mazzetti, C Hassan, M Gerloni
    Drug Metab. Pharmacokinet., 2019-01-17;34(3):172-180.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes
    Authors: SE Jin, H Ha, HK Shin, CS Seo
    Molecules, 2019-01-11;24(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  226. CD44 Assists the Topical Anti-Psoriatic Efficacy of Curcumin-Loaded Hyaluronan-Modified Ethosomes: A New Strategy for Clustering Drug in Inflammatory Skin
    Authors: Y Zhang, Q Xia, Y Li, Z He, Z Li, T Guo, Z Wu, N Feng
    Theranostics, 2019-01-01;9(1):48-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Intravascular heavy chain-modification of hyaluronan during endotoxic shock
    Authors: K Ni, A Gill, D Cao, K Koike, KS Schweitzer, S Garantziot, I Petrache
    Biochem Biophys Rep, 2018-12-26;17(0):114-121.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Cell Size-Based Decision-Making of a Viral Gene Circuit
    Authors: K Bohn-Wippe, EN Tevonian, Y Lu, MY Huang, MR Megaridis, RD Dar
    Cell Rep, 2018-12-26;25(13):3844-3857.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Tumor necrosis factor-like weak inducer of apoptosis induces inflammation in Graves' orbital fibroblasts
    Authors: SJ Lee, J Kim, J Ko, EJ Lee, HJ Koh, JS Yoon
    PLoS ONE, 2018-12-21;13(12):e0209583.
    Species: Human
    Sample Types: Whole Cells
  230. Long Non-Coding RNA Urothelial Carcinoma Associated 1 Promotes Proliferation, Migration and Invasion of Osteosarcoma Cells by Regulating microRNA-182
    Authors: Q Li, W Xing, X Gong, Y Wang
    Cell. Physiol. Biochem., 2018-11-27;51(3):1149-1163.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence
    Authors: M Rentschler, Y Chen, J Pahl, L Soria-Mart, H Braumüller, E Brenner, O Bischof, M Röcken, T Wieder
    Cell. Physiol. Biochem., 2018-11-26;51(3):1103-1118.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Agrimonia procera exerts antimicrobial effects, modulates the expression of defensins and cytokines in colonocytes and increases the immune response in lipopolysaccharide-challenged piglets
    Authors: T Gräber, H Kluge, S Granica, G Horn, J Kalbitz, C Brandsch, A Breitenste, C Brütting, GI Stangl
    BMC Vet. Res., 2018-11-15;14(1):346.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Astrocyte expression of the Drosophila TNF-alpha homologue, Eiger, regulates sleep in flies
    Authors: WM Vanderheyd, AG Goodman, RH Taylor, MG Frank, HPA Van Dongen, JR Gerstner
    PLoS Genet., 2018-10-31;14(10):e1007724.
    Species: Drosophila
    Sample Types: In Vivo
    Applications: In Vivo
  234. IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment
    Authors: L Mercurio, M Morelli, C Scarponi, EZ Eisenmesse, N Doti, G Pagnanelli, E Gubinelli, C Mazzanti, A Cavani, M Ruvo, CA Dinarello, C Albanesi, S Madonna
    Cell Death Dis, 2018-10-30;9(11):1104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Protective mechanisms of resveratrol derivatives against TNF-?-induced inflammatory responses in rat mesangial cells
    Authors: IT Lee, CF Lin, YL Huang, KY Chong, MF Hsieh, TH Huang, CY Cheng
    Cytokine, 2018-10-30;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines
    Authors: S Perriot, A Mathias, G Perriard, M Canales, N Jonkmans, N Merienne, C Meunier, L El Kassar, AL Perrier, DA Laplaud, M Schluep, N Déglon, R Du Pasquie
    Stem Cell Reports, 2018-10-25;11(5):1199-1210.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Divergent TCR-Initiated Calcium Signals Govern Recruitment versus Activation of Human Alloreactive Effector Memory T Cells by Endothelial Cells
    Authors: TD Manes, V Wang, JS Pober
    J. Immunol., 2018-10-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model
    Authors: GH Yang, C Zhang, N Wang, Y Meng, YS Wang
    Cytokine, 2018-09-28;111(0):350-356.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Catalase Enhances Viability of Human Chondrocytes in Culture by Reducing Reactive Oxygen Species and Counteracting Tumor Necrosis Factor-?-Induced Apoptosis
    Authors: S Li, X Yang, Z Feng, P Wang, W Zhu, S Cui
    Cell. Physiol. Biochem., 2018-09-27;49(6):2427-2442.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Activation of calcium-sensing receptor by allosteric agonists cinacalcet and AC-265347 abolishes the 1,25(OH)2D3-induced Ca2+ transport: Evidence that explains how the intestine prevents excessive Ca2+ absorption
    Authors: K Wongdee, M Rodrat, C Keadsai, W Jantarajit, J Teerapornp, J Thongbunch, N Charoenpha
    Arch. Biochem. Biophys., 2018-09-11;657(0):15-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Presenilin 1 Regulates NF-?B Activation via Association with Breakpoint Cluster Region and Casein Kinase II
    Authors: Y Tanaka, L Sabharwal, M Ota, I Nakagawa, JJ Jiang, Y Arima, H Ogura, M Okochi, M Ishii, D Kamimura, M Murakami
    J. Immunol., 2018-09-10;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  242. ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
    Authors: SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton
    Sci Rep, 2018-08-06;8(1):11720.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  243. ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion
    Authors: S Ishii, T Isozaki, H Furuya, H Takeuchi, Y Tsubokura, K Inagaki, T Kasama
    Arthritis Res. Ther., 2018-08-02;20(1):159.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-?
    Authors: M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay
    Physiol Rep, 2018-08-01;6(16):e13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress
    Authors: V Tisato, S Gallo, E Melloni, C Celeghini, A Passaro, G Zauli, P Secchiero, C Bergamini, A Trentini, G Bonaccorsi, G Valacchi, G Zuliani, C Cervellati
    Mediators Inflamm., 2018-07-26;2018(0):9629537.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. XAF1 forms a positive feedback loop with IRF-1 to drive apoptotic stress response and suppress tumorigenesis
    Authors: SI Jeong, JW Kim, KP Ko, BK Ryu, MG Lee, HJ Kim, SG Chi
    Cell Death Dis, 2018-07-24;9(8):806.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Elevated Expression of AXL May Contribute to the Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease Patients
    Authors: É Boros, Z Kellermaye, P Balogh, G Strifler, A Vörös, P Sarlós, Á Vincze, C Varga, I Nagy
    Mediators Inflamm., 2018-07-22;2018(0):3241406.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors
    Authors: JJ Seeley, RG Baker, G Mohamed, T Bruns, MS Hayden, SD Deshmukh, DE Freedberg, S Ghosh
    Nature, 2018-06-27;559(7712):114-119.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Sodium Butyrate Attenuates Diarrhea in Weaned Piglets and Promotes Tight Junction Protein Expression in Colon in a GPR109A-Dependent Manner
    Authors: W Feng, Y Wu, G Chen, S Fu, B Li, B Huang, D Wang, W Wang, J Liu
    Cell. Physiol. Biochem., 2018-06-27;47(4):1617-1629.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Proton irradiation orchestrates macrophage reprogramming through NF?B signaling
    Authors: G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels
    Cell Death Dis, 2018-06-27;9(7):728.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Lipoxin A4 Attenuates the Inflammatory Response in Stem Cells of the Apical Papilla via ALX/FPR2
    Authors: A Gaudin, M Tolar, OA Peters
    Sci Rep, 2018-06-11;8(1):8921.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
    Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
    Cell Death Dis, 2018-06-04;9(6):665.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Synergistic effect of interleukin-17 and tumor necrosis factor-α on inflammatory response in hepatocytes through interleukin-6 dependent and independent pathways
    Authors: A Beringer, N Thiam, J Molle, B Bartosch, P Miossec
    Clin. Exp. Immunol., 2018-05-31;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy
    Authors: SU Seo, SM Woo, HS Lee, SH Kim, KJ Min, TK Kwon
    Oncogene, 2018-05-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer
    Authors: AL Means, TJ Freeman, J Zhu, LG Woodbury, P Marincola-, C Wu, AR Meyer, CJ Weaver, C Padmanabha, H An, J Zi, BC Wessinger, R Chaturvedi, TD Brown, NG Deane, RJ Coffey, KT Wilson, JJ Smith, CL Sawyers, JR Goldenring, SV Novitskiy, MK Washington, C Shi, RD Beauchamp
    Cell Mol Gastroenterol Hepatol, 2018-05-24;6(3):257-276.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  256. Hyaluronic Acid Influence on Normal and Osteoarthritic Tissue-Engineered Cartilage
    Authors: S Hemmati-Sa, J Ringe, T Dehne, R Haag, M Sittinger
    Int J Mol Sci, 2018-05-19;19(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  257. Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
    Authors: AE Dodi, IO Ajayi, C Chang, M Beard, SL Ashley, SK Huang, VJ Thannickal, DJ Tschumperl, TH Sisson, JC Horowitz
    Respir. Res., 2018-05-10;19(1):91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. A20 regulates canonical wnt-signaling through an interaction with RIPK4
    Authors: BN Nakamura, A Glazier, MG Kattah, B Duong, Y Jia, D Campo, L Shao
    PLoS ONE, 2018-05-02;13(5):e0195893.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Anisakis pegreffii impacts differentiation and function of human dendritic cells
    Authors: C Napoletano, S Mattiucci, A Colantoni, F Battisti, IG Zizzari, H Rahimi, M Nuti, A Rughetti
    Parasite Immunol., 2018-05-01;0(0):e12527.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms
    Authors: E Vorkapic, A Kunath, D Wågsäter
    Mol Med Rep, 2018-04-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
    Authors: M Boyd, M Thodberg, M Vitezic, J Bornholdt, K Vitting-Se, Y Chen, M Coskun, Y Li, BZS Lo, P Klausen, P Jan Schwei, AG Pedersen, N Rapin, K Skovgaard, K Dahlgaard, R Andersson, TB Terkelsen, B Lilje, JT Troelsen, AM Petersen, KB Jensen, I Gögenur, P Thielsen, JB Seidelin, OH Nielsen, JT Bjerrum, A Sandelin
    Nat Commun, 2018-04-25;9(1):1661.
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  262. The proximal tubular ?7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction
    Authors: H Kim, SR Kim, J Je, K Jeong, S Kim, HJ Kim, KC Chang, SW Park
    Exp. Mol. Med., 2018-04-20;50(4):40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling
    Authors: JP Parisien, JJ Lenoir, R Mandhana, KR Rodriguez, K Qian, AM Bruns, CM Horvath
    EMBO Rep., 2018-04-16;0(0):.
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  264. Lymphatic exosomes promote dendritic cell migration along guidance cues
    Authors: M Brown, LA Johnson, DA Leone, P Majek, K Vaahtomeri, D Senfter, N Bukosza, H Schachner, G Asfour, B Langer, R Hauschild, K Parapatics, YK Hong, KL Bennett, R Kain, M Detmar, M Sixt, DG Jackson, D Kerjaschki
    J. Cell Biol., 2018-04-12;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells
    Authors: J Weiler, M Mohr, KS Zänker, T Dittmar
    Cell Commun. Signal, 2018-04-10;16(1):14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
    Authors: R Drolia, S Tenguria, AC Durkes, JR Turner, AK Bhunia
    Cell Host Microbe, 2018-04-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  267. High-Mobility Group Box 1 in Dry Eye Inflammation
    Authors: C Lema, RY Reins, RL Redfern
    Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1741-1750.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties
    Authors: M Gabl, M Sundqvist, A Holdfeldt, S Lind, J Mårtensson, K Christenso, T Marutani, C Dahlgren, H Mukai, H Forsman
    J. Immunol., 2018-03-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Restoration of E-cadherin by PPBICA protects against cisplatin-induced acute kidney injury by attenuating inflammation and programmed cell death
    Authors: L Gao, MM Liu, HM Zang, QY Ma, Q Yang, L Jiang, GL Ren, HD Li, WF Wu, JN Wang, B Wei, XQ Liu, C Jiang, C Huang, J Li, XM Meng
    Lab. Invest., 2018-03-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
    Authors: D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar
    Sci Rep, 2018-03-23;8(1):5126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation
    Authors: S Ikeya, JI Sakabe, T Yamada, T Naito, Y Tokura
    Sci Rep, 2018-03-22;8(1):5050.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Strigolactone GR24 and pinosylvin attenuate adipogenesis and inflammation of white adipocytes
    Authors: S Modi, N Yaluri, T Kokkola
    Biochem. Biophys. Res. Commun., 2018-03-21;0(0):.
    Species: Mouse
    Sample Types: 3T3-L1 adipocytes
    Applications: Bioassay
  273. Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients
    Authors: CM Dickinson, BW LeBlanc, MM Edhi, DS Heffernan, MH Faridi, V Gupta, WG Cioffi, X O'Brien, JS Reichner
    J Intensive Care, 2018-03-15;6(0):19.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Unraveling the interplay between senescent dermal fibroblasts and cutaneous squamous cell carcinoma cell lines at different stages of tumorigenesis
    Authors: M Toutfaire, E Dumortier, A Fattacciol, MV Steenbrugg, CM Proby, F Debacq-Cha
    Int. J. Biochem. Cell Biol., 2018-03-14;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  275. Sulforaphane rescues amyloid-? peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages
    Authors: KA Jhang, JS Park, HS Kim, YH Chong
    J Neuroinflammation, 2018-03-12;15(1):75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Nucleoside Diphosphate Kinase-3 (NME3) Enhances TLR5-Induced NF-?B Activation
    Authors: K Flentie, C Gonzalez, B Kocher, Y Wang, H Zhu, J Marasa, D Piwnica-Wo
    Mol. Cancer Res., 2018-03-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  277. LRRC15 promotes osteogenic differentiation of mesenchymal stem cells by modulating p65 cytoplasmic/nuclear translocation
    Authors: Y Wang, Y Liu, M Zhang, L Lv, X Zhang, P Zhang, Y Zhou
    Stem Cell Res Ther, 2018-03-09;9(1):65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. The induced RNA-binding protein, HuR targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis
    Authors: K Ouhara, S Munenaga, M Kajiya, K Takeda, S Matsuda, Y Sato, Y Hamamoto, T Iwata, S Yamasaki, K Akutagawa, N Mizuno, T Fujita, E Sugiyama, H Kurihara
    Clin. Exp. Immunol., 2018-03-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients
    Authors: E Canto, N Isobe, A Didonna, SL Hauser, JR Oksenberg
    J Neuroinflammation, 2018-03-07;15(1):72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  280. An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease
    Authors: AW Clarke, L Poulton, D Shim, D Mabon, D Butt, M Pollard, V Pande, J Husten, J Lyons, C Tian, AG Doyle
    MAbs, 2018-03-05;0(0):1-43.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance (SPR
  281. Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury
    Authors: S Wink, SW Hiemstra, S Huppelscho, JE Klip, B van de Wat
    Arch. Toxicol., 2018-03-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  282. BTKCys481Serdrives ibrutinib resistance via ERK1/2, and protects BTKWild-TypeMYD88 mutated cells by a paracrine mechanism
    Authors: JG Chen, X Liu, M Munshi, L Xu, N Tsakmaklis, MG Demos, A Kofides, ML Guerrera, GG Chan, CJ Patterson, KE Meid, J Gustine, T Dubeau, P Severns, JJ Castillo, ZR Hunter, J Wang, SJ Buhrlage, NS Gray, SP Treon, G Yang
    Blood, 2018-03-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Class 1-selective histone deacetylase inhibitors enhance HIV latency reversal while preserving the activity of HDAC isoforms necessary for maximal HIV gene expression
    Authors: TD Zaikos, MM Painter, NT Sebastian, VH Terry, KL Collins
    J. Virol., 2018-02-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling
    Authors: LH Wright, DJ Herr, SS Brown, H Kasiganesa, DR Menick
    JCI Insight, 2018-02-22;3(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  285. C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
    Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
    Elife, 2018-02-22;7(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Interactome analysis of transforming growth factor-?-activated kinase 1 inHelicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37
    Authors: O Sokolova, T Kähne, K Bryan, M Naumann
    Oncotarget, 2018-02-21;9(18):14366-14381.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Progesterone Inhibits Apoptosis in Fetal Membranes by Altering Expression of Both Pro- and Antiapoptotic Proteins
    Authors: Y Wang, VM Abrahams, G Luo, NG Norwitz, VV Snegovskik, SW Ng, ER Norwitz
    Reprod Sci, 2018-02-20;0(0):1933719118759.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  288. LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF-? stimulation
    Authors: Y Zhang, S Wang, H Dong, X Yi, J Zhang, X Liu, R Zhuang, Y Ding
    Clin. Exp. Immunol., 2018-02-20;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models
    Authors: A Lundin, L Delsing, M Clausen, P Ricchiuto, J Sanchez, A Sabirsh, M Ding, J Synnergren, H Zetterberg, G Brolén, R Hicks, A Herland, A Falk
    Stem Cell Reports, 2018-02-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Changes in the Anti-Allergic Activities of Sesame by Bioconversion
    Authors: TD Jung, SI Choi, SH Choi, BY Cho, WS Sim, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee
    Nutrients, 2018-02-14;10(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
    Authors: AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims
    Diabetologia, 2018-02-14;0(0):.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  292. Galectin-3 Plays an Important Role in Preterm Birth Caused by Dental Infection of Porphyromonas gingivalis
    Authors: M Miyauchi, M Ao, H Furusho, C Chea, A Nagasaki, S Sakamoto, T Ando, T Inubushi, K Kozai, T Takata
    Sci Rep, 2018-02-12;8(1):2867.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  293. The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts
    Authors: M Armaka, C Ospelt, M Pasparakis, G Kollias
    Nat Commun, 2018-02-12;9(1):618.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  294. CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
    Authors: MA Rapsomanik, XK Lun, S Woerner, M Laumanns, B Bodenmille, MR Martínez
    Nat Commun, 2018-02-12;9(1):632.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Filifactor alocis modulates human neutrophil antimicrobial functional responses
    Authors: JS Edmisson, S Tian, CL Armstrong, A Vashishta, CK Klaes, I Miralda, E Jimenez-Fl, J Le, Q Wang, RJ Lamont, SM Uriarte
    Cell. Microbiol., 2018-02-12;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  296. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
    Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
    Neurobiol. Dis., 2018-02-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  297. Virus-like infection induces human ? cell dedifferentiation
    Authors: M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann
    JCI Insight, 2018-02-08;3(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Up-regulation of SFTPB expression and attenuation of acute lung injury by pulmonary epithelial cell-specific NAMPT knockdown
    Authors: G Bi, L Wu, P Huang, S Islam, DP Heruth, LQ Zhang, DY Li, V Sampath, W Huang, BA Simon, RB Easley, SQ Ye
    FASEB J., 2018-02-08;0(0):fj201701059R.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
    Authors: L Chung, ET Orberg, AL Geis, JL Chan, K Fu, CED Shields, CM Dejea, P Fathi, J Chen, BB Finard, AJ Tam, FM McAllister, H Fan, X Wu, S Ganguly, A Lebid, P Metz, SW Van Meerbe, DL Huso, EC Wick, DM Pardoll, F Wan, S Wu, CL Sears, F Housseau
    Cell Host Microbe, 2018-02-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  300. EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes
    Authors: A Rutkowska, DR Shimshek, AW Sailer, KK Dev
    Neuropharmacology, 2018-01-31;133(0):121-128.
    Species: Human, Mouse, Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  301. ANKRD1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum
    Authors: L Bin, X Li, B Richers, JE Streib, JW Hu, P Taylor, DYM Leung
    J. Allergy Clin. Immunol., 2018-01-31;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  302. TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles
    Authors: M Frank-Bert, DS Pisetsky, C Kolling, BA Michel, RE Gay, A Jüngel, S Gay
    Front Immunol, 2018-01-29;9(0):28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  303. RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature
    Authors: WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson
    Front Immunol, 2018-01-29;9(0):80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  304. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway
    Authors: F Zhang, G Liu, D Li, C Wei, J Hao
    J. Immunol., 2018-01-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018-01-24;8(1):1561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  306. The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock
    Authors: TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley
    J Innate Immun, 2018-01-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies
    Authors: R Jalili, J Horecka, JR Swartz, RW Davis, HHJ Persson
    Proc. Natl. Acad. Sci. U.S.A., 2018-01-16;0(0):.
    Applications: Bioassay
  308. Bridging pro-inflammatory signals, synaptic transmission and protection in spinal explants in vitro
    Authors: M Medelin, V Giacco, A Aldinucci, G Castronovo, E Bonechi, A Sibilla, M Tanturli, M Torcia, L Ballerini, F Cozzolino, C Ballerini
    Mol Brain, 2018-01-15;11(1):3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  309. NF-?B inducing kinase is a therapeutic target for systemic lupus erythematosus
    Authors: HD Brightbill, E Suto, N Blaquiere, N Ramamoorth, S Sujatha-Bh, EB Gogol, GM Castanedo, BT Jackson, YC Kwon, S Haller, J Lesch, K Bents, C Everett, PB Kohli, S Linge, L Christian, K Barrett, A Jaochico, LM Berezhkovs, PW Fan, Z Modrusan, K Veliz, MJ Townsend, J DeVoss, AR Johnson, R Godemann, WP Lee, CD Austin, BS McKenzie, JA Hackney, JJ Crawford, ST Staben, MH Alaoui Ism, LC Wu, N Ghilardi
    Nat Commun, 2018-01-12;9(1):179.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Role of thyroid transcription factor-1 in transcriptional regulation of heme oxygenase-1
    Authors: B Jeong, HR Kim, NS Choi, BS Park, H Eom, JW Park, JG Kim, BJ Lee
    Biochem. Biophys. Res. Commun., 2018-01-04;0(0):.
    Species: Mouse, Rat
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  311. EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells
    Authors: YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo
    PLoS ONE, 2018-01-03;13(1):e0190638.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  312. RvD1 inhibits TNF?-induced c-Myc expression in normal intestinal epithelial cells and destabilizes hyper-expressed c-Myc in colon cancer cells
    Authors: X Zhong, HN Lee, YJ Surh
    Biochem. Biophys. Res. Commun., 2018-01-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells
    Authors: X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han
    J Cancer, 2018-01-01;9(2):367-374.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Arsenite exposure potentiates apoptosis-inducing effects of tumor necrosis factor-alpha- through reactive oxygen species
    Authors: P Singhirunn, B Moolmuang, K Lirdprapam, M Ruchirawat
    J Toxicol Sci, 2018-01-01;43(2):159-169.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
    Authors: Michael J Workman, John P Gleeson, Elissa J Troisi, Hannah Q Estrada, S Jordan Kerns, Christopher D Hinojosa, Geraldine A Hamilton, Stephan R Targan, Clive N Svendsen, Robert J Barrett
    Cellular and Molecular Gastroenterology and Hepatology, 2017-12-29;0(0):2352-345X.
    Species: Human
    Sample Types:
    Applications: Bioassay
  316. Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation
    Authors: T Tanaka, Y Zhou, T Ozawa, R Okizono, A Banba, T Yamamura, E Oga, A Muraguchi, H Sakurai
    J. Biol. Chem., 2017-12-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor
    Authors: AT Holdbrooks, CM Britain, SL Bellis
    J. Biol. Chem., 2017-12-12;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Long noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-?B pathway
    Authors: N Cheng, Y Guo
    Onco Targets Ther, 2017-12-11;10(0):5843-5853.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Association of HMGB1 with oxidative stress markers and regulators in PDR
    Authors: AM Abu El-Asr, K Alam, M Garcia-Ram, A Ahmad, MM Siddiquei, G Mohammad, A Mousa, G De Hertogh, G Opdenakker, R Simó
    Mol. Vis., 2017-12-05;23(0):853-871.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis
    Authors: Y Xu, S Xu, P Liu, M Koroleva, S Zhang, S Si, ZG Jin
    J Am Heart Assoc, 2017-11-30;6(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Diosgenin, an Activator of 1,25D3-MARRS Receptor/ERp57, Attenuates the Effects of TNF-? by Causing ADAM10-Dependent Ectodomain Shedding of TNF Receptor 1
    Authors: WS Yang, SY Moon, MJ Lee, EK Lee, SK Park
    Cell. Physiol. Biochem., 2017-10-27;43(6):2434-2445.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  322. MicroRNA-155 induction via TNF-? and IFN-? suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
    Authors: D Yee, KM Shah, MC Coles, TV Sharp, D Lagos
    J. Biol. Chem., 2017-10-24;292(50):20683-20693.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  323. IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis
    Authors: NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson
    Sci Rep, 2017-10-23;7(1):13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  324. Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13
    Authors: S Gogia, A Kelkar, C Zhang, KM Dayananda, S Neelamegha
    Blood Adv, 2017-10-20;1(23):2063-2074.
    Applications: Western Blot
  325. Tumor necrosis factor ? decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription
    Authors: MA Peplowski, AJ Vegso, V Iablokov, M Dicay, RS Zaheer, B Renaux, D Proud, MD Hollenberg, PL Beck, WK MacNaughto
    Physiol Rep, 2017-10-16;5(19):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. Healing of Preterm Ruptured Fetal Membranes
    Authors: H Mogami, A Hari Kisho, Y Akgul, RA Word
    Sci Rep, 2017-10-13;7(1):13139.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  327. The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation
    Authors: S Ebtehaj, EG Gruppen, M Parvizi, UJF Tietge, RPF Dullaart
    Cardiovasc Diabetol, 2017-10-12;16(1):132.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. HAT1 induces lung cancer cell apoptosis via up regulating Fas
    Authors: N Han, L Shi, Q Guo, W Sun, Y Yu, L Yang, X Zhang, M Zhang
    Oncotarget, 2017-09-23;8(52):89970-89977.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  329. A type of human skin dendritic cell marked by CD5 is associated with the development of inflammatory skin disease
    Authors: D Korenfeld, L Gorvel, A Munk, J Man, A Schaffer, T Tung, C Mann, E Klechevsky
    JCI Insight, 2017-09-21;2(18):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer
    Authors: ML Palisoul, JM Quinn, E Schepers, IS Hagemann, L Guo, K Reger, AR Hagemann, CK McCourt, PH Thaker, MA Powell, DG Mutch, KC Fuh
    Mol. Cancer Ther., 2017-09-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017-09-07;2(17):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  332. CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients
    Authors: M Matsushita, K Ozawa, T Suzuki, M Nakamura, N Nakano, S Kanchi, D Ichikawa, E Matsuki, M Sakurai, D Karigane, H Kasahara, N Tsukamoto, T Shimizu, T Mori, H Nakajima, S Okamoto, Y Kawakami, Y Hattori
    Blood Cancer J, 2017-09-01;7(9):e601.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation
    Authors: KA Bailey, FG Haj, SI Simon, AG Passerini
    Sci Rep, 2017-08-15;7(1):8196.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  334. Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
    Authors: N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo
    Sci Rep, 2017-08-15;7(1):8153.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Suppression of human arthritis synovial fibroblasts inflammation using dexamethasone-carbon nanotubes via increasing caveolin-dependent endocytosis and recovering mitochondrial membrane potential
    Authors: YK Lee, SW Kim, JY Park, WC Kang, YJ Kang, D Khang
    Int J Nanomedicine, 2017-08-10;12(0):5761-5779.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  336. MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
    Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
    Exp. Mol. Med., 2017-08-04;49(8):e363.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-?-Induced NF-?B Activation
    Authors: Z Wang, MY Li, C Mi, KS Wang, J Ma, X Jin
    Int J Mol Sci, 2017-07-26;18(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  338. Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
    Authors: E Couderc, F Morel, P Levillain, A Buffière-M, M Camus, C Paquier, C Bodet, JF Jégou, M Pohin, L Favot, M Garcia, V Huguier, J Mcheik, C Lacombe, H Yssel, G Guillet, FX Bernard, JC Lecron
    PLoS ONE, 2017-07-14;12(7):e0181486.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  339. Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching
    Authors: R Ahmad, B Rah, D Bastola, P Dhawan, AB Singh
    Sci Rep, 2017-07-11;7(1):5125.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  340. Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1
    Authors: J Yuzugulen, JA Douthwaite, EG Wood, IC Villar, NSA Patel, J Jegard, H Gaertner, I Rossitto-B, K Rose, O Hartley, PR Cutillas, A Ahluwalia, R Corder
    Sci Rep, 2017-07-10;7(1):4956.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  341. TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
    Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
    Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3496-3505.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  342. Frontline Science: c-Myc regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection
    Authors: R Connor, LD Jones, X Qiu, J Thakar, SB Maggirwar
    J. Leukoc. Biol., 2017-06-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  343. Identification of benzazole compounds that induce HIV-1 transcription
    Authors: JD Graci, D Michaels, G Chen, GM Schiralli, S Nodder, M Weetall, GM Karp, Z Gu, JM Colacino, AJ Henderson
    PLoS ONE, 2017-06-28;12(6):e0179100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  344. Interleukin-20 is triggered by TLR ligands and associates with disease activity in patients with rheumatoid arthritis
    Authors: L Šenolt, K Prajzlerov, H Hulejová, B Šumová, M Filková, D Veigl, K Pavelka, J Vencovský
    Cytokine, 2017-06-26;97(0):187-192.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  345. Upregulation of circulating microRNA-134 in adult-onset Still's disease and its use as potential biomarker
    Authors: TL Liao, YM Chen, CW Hsieh, HH Chen, HC Lee, WT Hung, KT Tang, DY Chen
    Sci Rep, 2017-06-23;7(1):4214.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    Authors: S Weis, AR Carlos, MR Moita, S Singh, B Blankenhau, S Cardoso, R Larsen, S Rebelo, S Schäuble, L Del Barrio, G Mithieux, F Rajas, S Lindig, M Bauer, MP Soares
    Cell, 2017-06-15;169(7):1263-1275.e14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  347. A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
    Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
    JCI Insight, 2017-06-15;2(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  348. ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
    Authors: JS Reyat, M Chimen, PJ Noy, J Szyroka, GE Rainger, MG Tomlinson
    J. Immunol., 2017-06-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  349. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells
    Authors: NT Hogan, MB Whalen, LK Stolze, NK Hadeli, MT Lam, JR Springstea, CK Glass, CE Romanoski
    Elife, 2017-06-06;6(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Proinflammatory Cytokines IL-6 and TNF-? Increased Telomerase Activity through NF-?B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells
    Authors: SS Chung, Y Wu, Q Okobi, D Adekoya, M Atefi, O Clarke, P Dutta, JV Vadgama
    Mediators Inflamm., 2017-06-06;2017(0):5958429.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  351. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
    Authors: R Santos, KC Vadodaria, BN Jaeger, A Mei, S Lefcochilo, APD Mendes, G Erikson, M Shokhirev, L Randolph-M, C Fredlender, S Dave, R Oefner, C Fitzpatric, M Pena, JJ Barron, M Ku, AM Denli, BE Kerman, P Charnay, JR Kelsoe, MC Marchetto, FH Gage
    Stem Cell Reports, 2017-06-06;8(6):1757-1769.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  352. AAV-based dual-reporter circuit for monitoring cell signaling in living human cells
    Authors: Z Zhang, Z Stickney, N Duong, K Curley, B Lu
    J Biol Eng, 2017-06-05;11(0):18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  353. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity
    Authors: D Sagar, NP Singh, R Ginwala, X Huang, R Philip, M Nagarkatti, P Nagarkatti, K Neumann, J Ruland, AM Andrews, SH Ramirez, ZK Khan, P Jain
    Sci Rep, 2017-06-02;7(1):2707.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  354. The involvement and possible mechanism of pro-inflammatory tumor necrosis factor alpha (TNF-?) in thoracic ossification of the ligamentum flavum
    Authors: C Zhang, Z Chen, X Meng, M Li, L Zhang, A Huang
    PLoS ONE, 2017-06-02;12(6):e0178986.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  355. Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis
    Authors: F Pan, H Xiang, J Yan, L Hong, L Zhang, Y Liu, X Feng, C Cai
    Scand. J. Immunol., 2017-06-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Identification of a small molecule that primes the type I interferon response to cytosolic DNA
    Authors: S Khiar, M Lucas-Hour, S Nisole, N Smith, O Helynck, M Bourgine, C Ruffié, JP Herbeuval, H Munier-Leh, F Tangy, PO Vidalain
    Sci Rep, 2017-05-31;7(1):2561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  357. RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program
    Authors: GG Jinesh, AM Kamat
    Cell Death Discov, 2017-05-29;3(0):17023.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  358. Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs)
    Authors: K Kinnunen, N Piippo, S Loukovaara, M Hytti, K Kaarnirant, A Kauppinen
    J Cell Commun Signal, 2017-05-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  359. An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors
    Authors: CH Lo, N Vunnam, AK Lewis, TL Chiu, BE Brummel, TM Schaaf, BD Grant, P Bawaskar, DD Thomas, JN Sachs
    SLAS Discov, 2017-05-22;0(0):2472555217706.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  360. TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
    Authors: M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya
    PLoS ONE, 2017-05-18;12(5):e0177771.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  361. Anti-Inflammatory Effects of OxPAPC Involve Endothelial Cell-Mediated Generation of LXA4.
    Authors: Yunbo Ke, Noureddine Zebda, Olga Oskolkova, Taras Afonyushk, Evgeny Berdyshev, Yufeng Tian, Fanyong Meng, Nicolene Sarich, Valery N Bochkov, Ji Ming Wang, Anna A Birukova, Konstantin G Birukov
    Circulation Research, 2017-05-18;0(0):1524-4571.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells
    Authors: M Fardoun, T Al-Shehabi, A El-Yazbi, K Issa, F Zouein, D Maaliki, R Iratni, AH Eid
    Oxid Med Cell Longev, 2017-05-15;2017(0):4134093.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  363. The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes
    Authors: A Alquraini, M Jamal, L Zhang, T Schmidt, GD Jay, KA Elsaid
    Arthritis Res. Ther., 2017-05-08;19(1):89.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  364. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
    Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
    Mol Metab, 2017-05-06;6(7):725-736.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  365. Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
    Authors: GW He, C Günther, V Thonn, YQ Yu, E Martini, B Buchen, MF Neurath, M Stürzl, C Becker
    J. Exp. Med., 2017-05-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  366. Apomorphine suppresses TNF-?-induced MMP-9 expression and cell invasion through inhibition of ERK/AP-1 signaling pathway in MCF-7 cells
    Authors: YS Jung, SO Lee
    Biochem. Biophys. Res. Commun., 2017-05-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  367. iTRAQ quantitative proteomic study in patients with thoracic ossification of the ligamentum flavum
    Authors: B Wang, Z Chen, X Meng, M Li, X Yang, C Zhang
    Biochem. Biophys. Res. Commun., 2017-04-26;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  368. Adipogenic differentiation of MSC alters their immunomodulatory properties in a tissue-specific manner
    Authors: H Munir, LS Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, HM McGettrick
    Stem Cells, 2017-04-24;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  369. Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions
    Authors: X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy
    J Extracell Vesicles, 2017-04-21;6(1):1314073.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  370. Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-?B in Human Serous Ovarian Epithelial Tumors
    Authors: H Choi, RMC Ignacio, ES Lee, AJ Wilson, D Khabele, DS Son
    Immune Netw, 2017-04-20;17(2):121-127.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis
    Authors: H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang
    PLoS ONE, 2017-04-18;12(4):e0176110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  372. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
    Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
    Nat. Immunol., 2017-04-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  373. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017-04-17;8(1):79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  374. Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect
    Authors: BS Patel, MJ Kugel, G Baehring, AJ Ammit
    Pulm Pharmacol Ther, 2017-04-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  375. Synovial cell death is regulated by TNF-?-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1?
    Authors: JW Lee, J Lee, SH Um, EY Moon
    Cell Death Dis, 2017-04-06;8(4):e2727.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  376. Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps
    Authors: BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu
    Allergy, 2017-04-04;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Roflumilast N-oxide in Combination with Formoterol Enhances the Anti-inflammatory Effect of Dexamethasone in ASM Cells
    Authors: Brijeshkumar S Patel
    Am. J. Respir. Cell Mol. Biol, 2017-04-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Inhibition of 6-phosphofructo-2-kinase suppresses fibroblast-like synoviocytes- mediated synovial inflammation and joint destruction in rheumatoid arthritis
    Authors: Y Zou, S Zeng, M Huang, Q Qiu, Y Xiao, M Shi, Z Zhan, L Liang, X Yang, H Xu
    Br. J. Pharmacol, 2017-03-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
    Authors: M Frank-Bert, M Trenkmann, K Klein, E Karouzakis, H Rehrauer, A Bratus, C Kolling, M Armaka, A Filer, BA Michel, RE Gay, CD Buckley, G Kollias, S Gay, C Ospelt
    Nat Commun, 2017-03-23;8(0):14852.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology
    Authors: M Silva, RK Fung, CB Donnelly, PA Videira, R Sackstein
    J. Immunol, 2017-03-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  381. In�vitro model of cerebral ischemia by using brain microvascular endothelial cells derived from human induced pluripotent stem cells
    Authors: Y Kokubu, T Yamaguchi, K Kawabata
    Biochem. Biophys. Res. Commun, 2017-03-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  382. Comprehensive proteome analysis of human skeletal muscle in cachexia and sarcopenia: A pilot study
    Authors: HA Ebhardt, S Degen, V Tadini, A Schilb, N Johns, CA Greig, KC Fearon, R Aebersold, C Jacobi
    J Cachexia Sarcopenia Muscle, 2017-03-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  383. Autophagy Impairment by Helicobacter pylori-induced Methylation Silencing of MAP1LC3Av1 Promotes Gastric Carcinogenesis
    Authors: JS Muhammad, S Nanjo, T Ando, S Yamashita, T Maekita, T Ushijima, Y Tabuchi, T Sugiyama
    Int. J. Cancer, 2017-03-14;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  384. Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-? through up-regulation of TNF receptor 1 in lung cancer cells.
    Authors: Bo Ra You, Bo Ram Han, Woo Hyun Park
    Oncotarget, 2017-03-14;0(0):1949-2553.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  385. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?
    Authors: JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey
    Proc. Natl. Acad. Sci. U.S.A, 2017-03-13;114(13):E2748-E2757.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis
    Authors: J Retzlaff, K Thamm, CC Ghosh, W Ziegler, H Haller, SM Parikh, S David
    Sci Rep, 2017-03-09;7(0):44113.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  387. A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification
    Authors: J Arebro, S Ekstedt, E Hjalmarsso, O Winqvist, S Kumlien Ge, LO Cardell
    Sci Rep, 2017-03-08;7(0):43568.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  388. Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-?B-Activating Factors through Direct Downregulation of IKK? and IKK?
    Authors: MH Hancock, LM Hook, J Mitchell, JA Nelson
    MBio, 2017-03-07;8(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
    Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
    J. Immunol, 2017-03-06;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  390. MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866
    Authors: P Huang, MW Lee, K Sadrerafi, DP Heruth, LQ Zhang, D Maulik, SQ Ye
    Drug Des Devel Ther, 2017-03-03;11(0):629-641.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  391. Analytical ultracentrifugation with fluorescence detection system reveals differences in complex formation between recombinant human TNF and different biological TNF antagonists in various environments
    Authors: E Krayukhina, M Noda, K Ishii, T Maruno, H Wakabayash, M Tada, T Suzuki, A Ishii-Wata, M Kato, S Uchiyama
    MAbs, 2017-03-03;9(4):664-679.
    Applications: Bioassay
  392. The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs
    Authors: F Salazar, D Awuah, OH Negm, F Shakib, AM Ghaemmagha
    Sci Rep, 2017-03-03;7(0):43337.
    Species: Complex Species Category
    Sample Types: Plasma
    Applications: Bioassay
  393. Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques
    Authors: SR DiNapoli, AM Ortiz, F Wu, K Matsuda, HL Twigg, VM Hirsch, K Knox, JM Brenchley
    JCI Insight, 2017-02-23;2(4):e91214.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  394. Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity
    Authors: L Israel, Y Wang, K Bulek, E Della Mina, Z Zhang, V Pedergnana, M Chrabieh, NA Lemmens, V Sancho-Shi, M Descatoire, T Lasseau, E Israelsson, L Lorenzo, L Yun, A Belkadi, A Moran, LE Weisman, F Vandenesch, F Batteux, S Weller, M Levin, J Herberg, A Abhyankar, C Prando, Y Itan, WJB van Wamel, C Picard, L Abel, D Chaussabel, X Li, B Beutler, PD Arkwright, JL Casanova, A Puel
    Cell, 2017-02-23;168(5):789-800.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  395. Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes
    Authors: Z Zhang, Q He, Y Tao, J Guo, F Xu, LY Wu, YS Zhao, D Wu, LY Zhou, JY Su, LX Song, C Xiao, X Li, CK Chang
    Am J Transl Res, 2017-02-15;9(2):454-465.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  396. A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer
    Authors: NV Sankpal, TP Fleming, PK Sharma, HJ Wiedner, WE Gillanders
    Oncogene, 2017-02-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  397. Substance P enhances proliferation and paracrine potential of adipose-derived stem cells in�vitro
    Authors: S Kim, J Piao, Y Son, HS Hong
    Biochem. Biophys. Res. Commun, 2017-02-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  398. Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells
    Authors: M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney
    Clin. Cancer Res, 2017-02-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  399. HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
    Authors: S Zhu, Q Zhang, X Sun, HJ Zeh, MT Lotze, R Kang, D Tang
    Cancer Res, 2017-01-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  400. STAT3/NF-?B-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer
    Authors: WY Kuo, L Hwu, CY Wu, JS Lee, CW Chang, RS Liu
    Theranostics, 2017-01-15;7(3):647-663.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  401. IFN type I and II induce BAFF secretion from human decidual stromal cells
    Authors: AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin
    Sci Rep, 2017-01-06;7(0):39904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  402. A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation
    Authors: A Smole, D Lain??ek, U Bezeljak, S Horvat, R Jerala
    Mol. Ther, 2017-01-04;25(1):102-119.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  403. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
    Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
    Autophagy, 2017-01-01;0(0):0.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  404. Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy
    Authors: Jong Baeck Lim
    Yonsei Med. J., 2017-01-01;58(1):43-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  405. Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy
    Authors: R Havunen, M Siurala, S Sorsa, S Grönberg-V, M Behr, S Tähtinen, JM Santos, P Karell, J Rusanen, DM Nettelbeck, A Ehrhardt, A Kanerva, A Hemminki
    Mol Ther Oncolytics, 2016-12-31;4(0):77-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  406. Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis
    Authors: Anja Kerstein
    J. Autoimmun, 2016-12-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  407. Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
    Authors: Shailesh Dudhgaonka
    J. Immunol, 2016-12-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  408. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling
    Authors: R Liu, C Tang, A Shen, H Luo, X Wei, D Zheng, C Sun, Z Li, D Zhu, T Li, Z Wu
    Oncotarget, 2016-12-20;7(51):85079-85096.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  409. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling
    Sci Rep, 2016-12-19;6(0):39190.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  410. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
    Proc. Natl. Acad. Sci. U.S.A, 2016-12-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  411. Adsorption as a Contributor for Inflammatory Mediators Removal by Different Hemofiltration Membranes: A Pilot Study
    Authors: Benjamin Malard
    Artif Organs, 2016-12-02;0(0):.
    Species: Human
    Sample Types: Plasma
    Applications: Hemofiltration Procedure
  412. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
    Stem Cell Res Ther, 2016-12-01;7(1):175.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  413. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
    PLoS ONE, 2016-12-01;11(12):e0167361.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  414. Bioequivalence, safety and immunogenicity of BI 695501, an adalimumab biosimilar candidate, compared with the reference biologic in a randomized, double-blind, active-comparator Phase I clinical study (VOLTAIRE�-PK) in healthy subjects
    Authors: Niklas Czeloth
    Expert Opin Investig Drugs, 2016-12-01;0(0):.
    Applications: Bioassay
  415. Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells
    Invest. Ophthalmol. Vis. Sci, 2016-12-01;57(15):6482-6495.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation
    Authors: Andrea Todisco
    Am. J. Physiol. Gastrointest. Liver Physiol., 2016-11-17;0(0):ajpgi.00169.2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  417. Anti-inflammatory treatment improves high-density lipoprotein function in rheumatoid arthritis
    Authors: John Deanfield
    Heart, 2016-11-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  418. Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression
    Authors: Martin F Reiner
    Cardiovasc. Res, 2016-11-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  419. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population
    Authors: Derek N J Hart
    J. Immunol., 2016-11-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  420. Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models
    Authors: Nathalie Castex-Riz
    Clin Cosmet Investig Dermatol, 2016-11-10;9(0):421-434.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  421. Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme
    Authors: Joan W Conaway
    J. Biol. Chem., 2016-11-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  422. Extracellular Microvesicle Production by Human Eosinophils Activated by Inflammatory Stimuli
    Authors: Rossana C N Melo
    Front Cell Dev Biol, 2016-10-27;4(0):117.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  423. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations
    Authors: Robert Sabat
    Mediators Inflamm., 2016-10-23;2016(0):4097574.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  424. Bradykinin stimulates protein kinase D-mediated colonic myofibroblast migration via cyclooxygenase-2 and heat shock protein 27
    Authors: Eric Chu
    J. Surg. Res, 2016-10-20;209(0):191-198.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  425. Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease
    Sci Rep, 2016-10-14;6(0):35282.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  426. Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
    Nat Commun, 2016-09-27;7(0):12951.
    Species: Ovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  427. Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation
    J Biol Chem, 2016-09-20;0(0):.
    Species: Human, Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  428. Cytokines TNF-?, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells.
    Authors: Angela P Bastidas-C, Astrid D Bakker, Behrouz Zandieh-D, Cornelis J Kleverlaa, Nathalie Bravenboe, Tim Forouzanf, Jenneke Klein-Nul
    Stem Cells International, 2016-09-07;0(0):1687-966X.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17
    PLoS ONE, 2016-09-02;11(9):e0161759.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  430. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
    Mol Ther Methods Clin Dev, 2016-08-24;3(0):16056.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  431. Negative regulation of NF-?B p65 activity by serine 536 phosphorylation.
    Authors: Jean-Philippe Pradère, Céline Hernandez, Christiane Koppe, Richard A Friedman, Tom Luedde, Robert F Schwabe
    Science Signaling, 2016-08-23;0(0):1937-9145.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  432. IRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma
    J Clin Endocrinol Metab, 2016-08-17;0(0):jc20162276.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  433. HDL function is impaired in acute myocardial infarction independent of plasma HDL cholesterol levels
    Authors: Wijtske Annema
    J Clin Lipidol, 2016-08-17;10(6):1318-1328.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  434. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    Cell, 2016-08-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  435. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis
    Cell Death Dis, 2016-06-30;7(6):e2287.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  436. Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement
    Authors: Michael A Schmid
    PLoS Pathog, 2016-06-16;12(6):e1005676.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  437. Interferon-? and Tumor Necrosis Factor-? Polarize Bone Marrow Stromal Cells Uniformly to a Th1 Phenotype
    Sci Rep, 2016-05-23;6(0):26345.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  438. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells
    PLoS ONE, 2016-05-20;11(5):e0156145.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  439. Mycobacterium massiliense Induces Macrophage Extracellular Traps with Facilitating Bacterial Growth
    PLoS ONE, 2016-05-18;11(5):e0155685.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  440. IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice
    J Immunol, 2016-05-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  441. Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7
    Authors: MM Halpert, V Konduri, D Liang, Y Chen, JB Wing, S Paust, JM Levitt, WK Decker
    Stem Cells Dev., 2016-05-02;25(10):774-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  442. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
    Authors: R Yosef, N Pilpel, R Tokarsky-A, A Biran, Y Ovadya, S Cohen, E Vadai, L Dassa, E Shahar, R Condiotti, I Ben-Porath, V Krizhanovs
    Nat Commun, 2016-04-06;7(0):11190.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  443. Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
    Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
    Respir Res, 2016-04-04;17(1):36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  444. Endothelial Surface Protrusion by a Point Force
    Authors: Y Chen, L Lu, JY Shao
    Biophys. J, 2016-03-08;110(5):1150-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  445. Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.
    Authors: Lu W, Sun J, Yoon J, Zhang Y, Zheng L, Murphy E, Mattson M, Lenardo M
    PLoS ONE, 2016-01-25;11(1):e0147792.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  446. Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.
    Authors: Guo Z, Zheng L, Liao X, Geller D
    PLoS ONE, 2016-01-11;11(1):e0146640.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  447. A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis.
    Authors: Whitmore L, Hook J, Philiph A, Hilkin B, Bing X, Ahn C, Wong H, Ferguson P, Moreland J
    J Immunol, 2016-01-04;196(3):1376-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  448. Tissue Inhibitor of Metalloproteinase-4 Triggers Apoptosis in Cervical Cancer Cells.
    Authors: Lizarraga F, Ceballos-Cancino G, Espinosa M, Vazquez-Santillan K, Maldonado V, Melendez-Zajgla J
    PLoS ONE, 2015-08-20;10(8):e0135929.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  449. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
    Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
    Eur J Immunol, 2015-08-17;45(10):2937-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  450. CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis.
    Authors: Zhao Y, Ma C, Wu L, Iwai K, Ashwell J, Oltz E, Ballard D, Jain A
    J Biol Chem, 2015-07-29;290(36):22076-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  451. Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.
    Authors: Divakar S, Ramana Reddy M, Cosenza S, Baker S, Perumal D, Antonelli A, Brody J, Akula B, Parekh S, Premkumar Reddy E
    Leukemia, 2015-07-15;30(1):86-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  452. IL-4 Downregulates IL-1beta and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine.
    Authors: Onderdijk A, Baerveldt E, Kurek D, Kant M, Florencia E, Debets R, Prens E
    J Immunol, 2015-07-13;195(4):1744-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  453. Interleukin-1 family cytokines and their regulatory proteins in normal pregnancy and pre-eclampsia.
    Authors: Southcombe J, Redman C, Sargent I, Granne I
    Clin Exp Immunol, 2015-06-29;181(3):480-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  454. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
    Authors: Watson R, Buck J, Levin L, Winger R, Wang J, Arase H, Muller W
    J Exp Med, 2015-06-22;212(7):1021-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  455. Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
    Authors: Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D
    J Transl Med, 2015-06-20;13(0):197.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  456. 6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFkappaB activation in airway epithelial cells.
    Authors: Kurakula K, Hamers A, van Loenen P, de Vries C
    Respir Res, 2015-06-19;16(0):73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  457. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
    Authors: Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, Schaeren-Wiemers N, Du Pasquier R
    J Neuroinflammation, 2015-06-16;12(0):119.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  458. Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure.
    Authors: Miranda A, Funes J, Sanchez N, Limia C, Mesa M, Quezada S, Perez R, de Leon J
    Cancer Res, 2015-06-11;75(15):3032-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  459. Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
    Authors: Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, Lidov H, Hopkins G, DU L, Belkadi A, Chrabieh M, Itan Y, Picard C, Fournet J, Eibel H, Tsitsikov E, Pai S, Abel L, Al-Herz W, Casanova J, Israel A, Notarangelo L
    J Exp Med, 2015-05-25;212(6):939-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  460. Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage.
    Authors: Catanzaro D, Rancan S, Orso G, Dall'Acqua S, Brun P, Giron M, Carrara M, Castagliuolo I, Ragazzi E, Caparrotta L, Montopoli M
    PLoS ONE, 2015-05-08;10(5):e0125375.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  461. The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.
    Authors: He Y, Zheng Q, Jiang M, Sun S, Christiansen T, Kassem M, Karsdal M, Bay-Jensen A
    PLoS ONE, 2015-04-24;10(0):.
    Species: Bovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  462. Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Skuland T, Johansen B
    PLoS ONE, 2015-04-20;10(4):e0119088.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  463. Facile supermolecular aptamer inhibitors of L-selectin.
    Authors: Chang, Elizabet, Eckert, Mark A, Ali, M Monsur, Riazifar, Hamidrez, Pone, Egest J, Liu, Linan, Zhao, Weian
    PLoS ONE, 2015-03-31;10(3):e0123034.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  464. Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk.
    Authors: Irvin S, Herold B
    PLoS ONE, 2015-03-23;10(3):e0121135.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  465. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
    Authors: Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E
    Nat Med, 2015-03-16;21(4):363-72.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  466. L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.
    Authors: Rzeniewicz K, Newe A, Rey Gallardo A, Davies J, Holt M, Patel A, Charras G, Stramer B, Molenaar C, Tedder T, Parsons M, Ivetic A
    Proc Natl Acad Sci U S A, 2015-03-09;112(12):E1461-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  467. Adrenal steroids modulate the immune response during Brucella abortus infection by a mechanism that depends on the regulation of cytokine production.
    Authors: Gentilini M, Velasquez L, Barrionuevo P, Arriola Benitez P, Giambartolomei G, Delpino M
    Infect Immun, 2015-03-02;83(5):1973-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  468. RIP1 Kinase Is an Oncogenic Driver in Melanoma.
    Authors: Liu X, Lai F, Yan X, Jiang C, Guo S, Wang C, Croft A, Tseng H, Wilmott J, Scolyer R, Jin L, Zhang X
    Cancer Res, 2015-02-27;75(8):1736-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  469. Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein delta.
    Authors: Yamaguchi J, Tanaka T, Eto N, Nangaku M
    Kidney Int, 2015-02-18;88(2):262-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  470. RelB/p50 complexes regulate cytokine-induced YKL-40 expression.
    Authors: Bhardwaj R, Yester J, Singh S, Biswas D, Surace M, Waters M, Hauser K, Yao Z, Boyce B, Kordula T
    J Immunol, 2015-02-13;194(6):2862-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  471. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor kappaB (NF-kappaB) signaling.
    Authors: Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, Zhang Y, Guo S, Qin X, Li T, Li W, Li A, Zhang X, Li H
    J Biol Chem, 2015-02-13;290(16):10395-405.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  472. The cerebral cavernous malformation 3 gene is necessary for senescence induction.
    Authors: Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, Zalvide J
    Aging Cell, 2015-02-05;14(2):274-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  473. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
    Authors: Herova M, Schmid M, Gemperle C, Hersberger M
    J Immunol, 2015-01-30;194(5):2330-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  474. Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting beta(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.
    Authors: Rider C, Shah S, Miller-Larsson A, Giembycz M, Newton R
    PLoS ONE, 2015-01-27;10(1):e0116773.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  475. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
    Authors: Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M
    Invest Ophthalmol Vis Sci, 2015-01-20;56(2):1051-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  476. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment.
    Authors: Rousseau M, Belleannee C, Duchez A, Cloutier N, Levesque T, Jacques F, Perron J, Nigrovic P, Dieude M, Hebert M, Gelb M, Boilard E
    PLoS ONE, 2015-01-14;10(1):e0116812.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  477. Role of transforming growth factor-activated kinase-1 on tumor necrosis factor-alpha actions in human adipose tissue-derived stromal cells.
    Authors: Lee S, Lee J, Shin K, Kim D, Kim Y, Bae Y, Jung J
    Stem Cells Dev, 2014-12-31;24(7):836-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  478. BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes.
    Authors: Chan C, Fang C, Qiao Y, Yarilina A, Prinjha R, Ivashkiv L
    Eur J Immunol, 2014-12-01;45(1):287-97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  479. Nuclear FAM21 participates in NF-kappaB-dependent gene regulation in pancreatic cancer cells.
    Authors: Deng Z, Gomez T, Osborne D, Phillips-Krawczak C, Zhang J, Billadeau D
    J Cell Sci, 2014-11-27;128(2):373-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  480. Anti-apoptotic NF-kappaB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF production.
    Authors: Muller I, Beissert S, Kulms D
    J Invest Dermatol, 2014-11-07;135(3):851-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  481. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
    Authors: Lam, Sharon, Sung, Julia, Cruz, Conrad, Castillo-Caro, Paul, Ngo, Minhtran, Garrido, Carolina, Kuruc, Joann, Archin, Nancie, Rooney, Cliona, Margolis, David, Bollard, Catherin
    Mol Ther, 2014-11-04;23(2):387-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  482. Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.
    Authors: Leslie J, Huang S, Opp J, Nagy M, Kobayashi M, Young V, Spence J
    Infect Immun, 2014-10-13;83(1):138-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  483. Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
    Authors: Cubbon R, Yuldasheva N, Viswambharan H, Mercer B, Baliga V, Stephen S, Askham J, Sukumar P, Skromna A, Mughal R, Walker A, Bruns A, Bailey M, Galloway S, Imrie H, Gage M, Rakobowchuk M, Li J, Porter K, Ponnambalam S, Wheatcroft S, Beech D, Kearney M
    Stem Cells, 2014-10-01;32(10):2714-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  484. Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation.
    Authors: Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox A, Asada Y, Wierman M, Hirata K, Rikitake Y
    PLoS ONE, 2014-09-24;9(9):e107236.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  485. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
    Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
    PLoS ONE, 2014-09-03;9(9):e106673.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  486. Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
    Authors: De Simone V, Franze E, Ronchetti G, Colantoni A, Fantini M, Di Fusco D, Sica G, Sileri P, MacDonald T, Pallone F, Monteleone G, Stolfi C
    Oncogene, 2014-09-01;34(27):3493-503.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  487. DeltaNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis.
    Authors: Kubo T, Kamekura R, Kumagai A, Kawata K, Yamashita K, Mitsuhashi Y, Kojima T, Sugimoto K, Yoneta A, Sumikawa Y, Yamashita T, Sato N, Himi T, Ichimiya S
    PLoS ONE, 2014-08-29;9(8):e105498.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  488. Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-alpha-induced procoagulant activity and apoptosis in endothelial cells.
    Authors: Ohkawara H, Ishibashi T, Sugimoto K, Ikeda K, Ogawa K, Takeishi Y
    PLoS ONE, 2014-08-27;9(8):e105697.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  489. Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer.
    Authors: Kim S, Chung H, Lee K, Lim J
    J Transl Med, 2014-08-21;12(0):229.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  490. Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal.
    Authors: Salzano S, Checconi P, Hanschmann E, Lillig C, Bowler L, Chan P, Vaudry D, Mengozzi M, Coppo L, Sacre S, Atkuri K, Sahaf B, Herzenberg L, Herzenberg L, Mullen L, Ghezzi P
    Proc Natl Acad Sci U S A, 2014-08-05;111(33):12157-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  491. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
    Authors: Bailon E, Ugarte-Berzal E, Amigo-Jimenez I, Van den Steen P, Opdenakker G, Garcia-Marco J, Garcia-Pardo A
    J Leukoc Biol, 2014-08-01;96(2):185-99.
    Species: Human
    Sample Types: N/A
  492. Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.
    Authors: Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K
    J Immunol, 2014-07-30;193(5):2297-305.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  493. Plasticity-related gene 5 promotes spine formation in murine hippocampal neurons.
    Authors: Coiro P, Stoenica L, Strauss U, Brauer A
    J Biol Chem, 2014-07-29;289(36):24956-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  494. p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-kappaB subunit.
    Authors: O'Hara A, Simpson J, Morin P, Loveridge C, Williams A, Novo S, Stark L
    J Cell Sci, 2014-07-29;127(0):3659-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  495. Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.
    Authors: Ji, Weidong, Yang, Mei, Praggastis, Alexandr, Li, Yonghao, Zhou, Huanjiao, He, Yun, Ghazvinian, Roxanne, Cincotta, Dylan J, Rice, Kevin P, Min, Wang
    PLoS ONE, 2014-07-28;9(7):e103224.
    Species: Bovine, Human
    Sample Types: Whole Cells
    Applications: Bioassay
  496. Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.
    Authors: Chattopadhyay A, Hood B, Conrads T, Redner R
    Mol Cancer Res, 2014-07-17;12(9):1283-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  497. A20 deficiency causes spontaneous neuroinflammation in mice.
    Authors: Guedes R, Csizmadia E, Moll H, Ma A, Ferran C, da Silva C
    J Neuroinflammation, 2014-07-16;11(0):122.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  498. The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.
    Authors: Wu L, Wang C, Boisson B, Misra S, Rayman P, Finke J, Puel A, Casanova J, Li X
    J Immunol, 2014-07-14;193(4):1590-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  499. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
    Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
    PLoS ONE, 2014-07-10;9(7):e101937.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  500. Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB231 partly through suppression of the Akt pathway.
    Authors: Jin H, Lee W, Eun S, Jung J, Park H, Kim G, Choi Y, Ryu C, Jung J, Hong S, Shin S, Kim H
    Int J Oncol, 2014-07-04;45(4):1629-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  501. A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.
    Authors: Lewis, Nuruddee, Patnaude, Lori A, Pelletier, Josephin, Souza, Donald J, Lukas, Susan M, King, F James, Hill, Jonathan, Stefanopoulos, Dimitria, Ryan, Kelli, Desai, Sudha, Skow, Donna, Kauschke, Stefan G, Broermann, Andre, Kuzmich, Daniel, Harcken, Christia, Hickey, Eugene R, Modis, Louise K
    PLoS ONE, 2014-06-26;9(6):e100883.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  502. Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
    Authors: Chiang, En-Pei I, Tsai, Shu-Yao, Kuo, Yueh-Hsi, Pai, Man-Hui, Chiu, Hsi-Lin, Rodriguez, Raymond, Tang, Feng-Yao
    PLoS ONE, 2014-06-24;9(6):e99631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  503. PHLDA1 expression is controlled by an estrogen receptor-NFkappaB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres.
    Authors: Kastrati I, Canestrari E, Frasor J
    Oncogene, 2014-06-23;34(18):2309-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  504. Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer.
    Authors: Shindo Y, Hazama S, Maeda Y, Matsui H, Iida M, Suzuki N, Yoshimura K, Ueno T, Yoshino S, Sakai K, Suehiro Y, Yamasaki T, Hinoda Y, Oka M
    J Transl Med, 2014-06-19;12(0):175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  505. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
    Authors: Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai Y, Richardson P, Utsugi T, Iwama A, Anderson K
    Cancer Res, 2014-06-16;74(16):4458-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  506. Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1.
    Authors: Zhao C, Pavicic P, Datta S, Sun D, Novotny M, Hamilton T
    J Immunol, 2014-06-11;193(2):879-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  507. A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS).
    Authors: Negm O, Mannsperger H, McDermott E, Drewe E, Powell R, Todd I, Fairclough L, Tighe P
    Eur J Immunol, 2014-06-10;44(7):2096-110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  508. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis.
    Authors: Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M, Bogiatzi S, Fernandez M, Touzot M, Bichet J, Reyal F, Paronetto M, Chiricozzi A, Chimenti S, Nasorri F, Cavani A, Kislat A, Homey B, Soumelis V
    J Allergy Clin Immunol, 2014-06-06;134(2):373-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  509. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta.
    Authors: Zhao Y, Xiao X, Frank S, Lin H, Xia Y
    Am J Physiol Endocrinol Metab, 2014-06-03;307(2):E186-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  510. Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells.
    Authors: Tengroth L, Millrud C, Kvarnhammar A, Kumlien Georen S, Latif L, Cardell L
    PLoS ONE, 2014-06-02;9(6):e98239.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  511. Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.
    Authors: Ohlsson S, Ohlsson S, Soderberg D, Gunnarsson L, Pettersson A, Segelmark M, Hellmark T
    Clin Exp Immunol, 2014-06-01;176(3):363-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  512. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.
    Authors: Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, Man H, Muller G, Stirling D, Chopra R
    Cell Signal, 2014-05-29;26(9):2016-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  513. Glucocorticoid-induced reversal of interleukin-1beta-stimulated inflammatory gene expression in human oviductal cells.
    Authors: Backman S, Kollara A, Haw R, Stein L, Brown T
    PLoS ONE, 2014-05-21;9(5):e97997.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  514. Plasma cells in the mucosa of patients with inflammatory bowel disease produce granzyme B and possess cytotoxic activities.
    Authors: Cupi M, Sarra M, Marafini I, Monteleone I, Franze E, Ortenzi A, Colantoni A, Sica G, Sileri P, Rosado M, Carsetti R, MacDonald T, Pallone F, Monteleone G
    J Immunol, 2014-05-16;192(12):6083-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  515. IL-2 phosphorylates STAT5 to drive IFN-gamma production and activation of human dendritic cells.
    Authors: Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, Velge-Roussel F, Baron C, Lebranchu Y
    J Immunol, 2014-05-14;192(12):5660-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  516. TL1A increased the differentiation of peripheral Th17 in rheumatoid arthritis.
    Authors: Zhou M, Liu R, Su D, Feng X, Li X
    Cytokine, 2014-05-13;69(1):125-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  517. A splicing variant of NME1 negatively regulates NF-kappaB signaling and inhibits cancer metastasis by interacting with IKKbeta.
    Authors: You D, Park C, Lee H, Moon M, Kang J, Lee C, Oh S, Ahn C, Seong J, Hwang J
    J Biol Chem, 2014-05-08;289(25):17709-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  518. Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells.
    Authors: Kim, Dae Won, Zloza, Andrew, Broucek, Joseph, Schenkel, Jason M, Ruby, Carl, Samaha, Georges, Kaufman, Howard L
    J Transl Med, 2014-05-06;12(0):113.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  519. Osteodifferentiated mesenchymal stem cells from bone marrow and adipose tissue express HLA-G and display immunomodulatory properties in HLA-mismatched settings: implications in bone repair therapy.
    Authors: Montespan F, Deschaseaux F, Sensebe L, Carosella E, Rouas-Freiss N
    J Immunol Res, 2014-04-30;2014(0):230346.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  520. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.
    Authors: Catanzaro J, Sheshadri N, Pan J, Sun Y, Shi C, Li J, Powers R, Crawford H, Zong W
    Nat Commun, 2014-04-23;5(0):3729.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  521. Tumor necrosis factor (TNF)-alpha induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-kappaB p65 methylation.
    Authors: Harris D, Bandyopadhyay S, Maxwell T, Willard B, DiCorleto P
    J Biol Chem, 2014-04-21;289(22):15328-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  522. Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.
    Authors: Singer B, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza L, Heyl K, Muller M, Weimann A, Zweigner J, Slevogt H
    PLoS ONE, 2014-04-17;9(4):e94106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  523. A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells.
    Authors: Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, Albar J, Garcia-Marco J, Garcia-Pardo A
    J Biol Chem, 2014-04-16;289(22):15340-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  524. Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation.
    Authors: Mambetsariev I, Tian Y, Wu T, Lavoie T, Solway J, Birukov K, Birukova A
    PLoS ONE, 2014-04-16;9(4):e92670.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  525. Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation.
    Authors: Singh, Meera V, Davidson, Donna C, Jackson, Joseph W, Singh, Vir B, Silva, Jharon, Ramirez, Servio H, Maggirwar, Sanjay B
    J Immunol, 2014-04-11;192(10):4674-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  526. Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice.
    Authors: Liu J, Ren Y, Kang L, Zhang L
    PLoS ONE, 2014-04-10;9(4):e94912.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  527. Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members.
    Authors: Beigel F, Friedrich M, Probst C, Sotlar K, Goke B, Diegelmann J, Brand S
    PLoS ONE, 2014-04-07;9(4):e93498.
    Applications: Western Blot
  528. Cell density impacts epigenetic regulation of cytokine-induced E-selectin gene expression in vascular endothelium.
    Authors: Hamada K, Osaka M, Yoshida M
    PLoS ONE, 2014-04-01;9(4):e90502.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  529. Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids.
    Authors: Rahman M, Alkhouri H, Tang F, Che W, Ge Q, Ammit A
    PLoS ONE, 2014-03-19;9(3):e92466.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  530. Toxoplasma gondii virulence factor ROP18 inhibits the host NF-kappaB pathway by promoting p65 degradation.
    Authors: Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J
    J Biol Chem, 2014-03-19;289(18):12578-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  531. Rad GTPase inhibits the NFkappaB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation.
    Authors: Hsiao B, Chang T, Wu I, Chen M
    Cell Signal, 2014-03-13;26(7):1437-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  532. Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels.
    Authors: You B, Park W
    Int J Oncol, 2014-03-12;44(5):1745-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  533. MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
    Authors: Lopez-Ramirez M, Wu D, Pryce G, Simpson J, Reijerkerk A, King-Robson J, Kay O, de Vries H, Hirst M, Sharrack B, Baker D, Male D, Michael G, Romero I
    FASEB J, 2014-03-06;28(6):2551-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  534. Luteolin inhibits human keratinocyte activation and decreases NF-kappaB induction that is increased in psoriatic skin.
    Authors: Weng Z, Patel A, Vasiadi M, Therianou A, Theoharides T
    PLoS ONE, 2014-02-28;9(2):e90739.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  535. Tumour necrosis factor-alpha regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappaB and AP-1.
    Authors: Kankaanranta H, Ilmarinen P, Zhang X, Adcock I, Lahti A, Barnes P, Giembycz M, Lindsay M, Moilanen E
    PLoS ONE, 2014-02-28;9(2):e90298.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  536. The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
    Authors: Lessey-Morillon E, Osborne L, Monaghan-Benson E, Guilluy C, O'Brien E, Superfine R, Burridge K
    J Immunol, 2014-02-28;192(7):3390-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  537. MicroRNA-26b suppresses the NF-kappaB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.
    Authors: Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang S
    Mol Cancer, 2014-02-24;13(0):35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  538. The multifunctional growth factor midkine promotes proliferation and migration in pancreatic cancer.
    Authors: Rawnaq T, Dietrich L, Wolters-Eisfeld G, Uzunoglu F, Vashist Y, Bachmann K, Simon R, Izbicki J, Bockhorn M, Gungor C
    Mol Cancer Res, 2014-02-24;12(5):670-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  539. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.
    Authors: Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, Barra C, Comerma L, Chudnovskiy A, Gentile M, Llige D, Cols M, Serrano S, Arostegui J, Juan M, Yague J, Merad M, Fagarasan S, Cerutti A
    Nat Immunol, 2014-02-23;15(4):354-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  540. A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
    Authors: Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M
    PLoS ONE, 2014-02-14;9(2):e88714.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  541. Endothelial activation by platelets from sickle cell anemia patients.
    Authors: Proenca-Ferreira R, Brugnerotto A, Garrido V, Dominical V, Vital D, Ribeiro M, dos Santos M, Traina F, Olalla-Saad S, Costa F, Conran N
    PLoS ONE, 2014-02-13;9(2):e89012.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  542. Vaspin inhibits cytokine-induced nuclear factor-kappa B activation and adhesion molecule expression via AMP-activated protein kinase activation in vascular endothelial cells.
    Authors: Jung C, Lee M, Kang Y, Lee Y, Yoon H, Kang S, Lee W, Park J
    Cardiovasc Diabetol, 2014-02-12;13(0):41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  543. The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting beta2-adrenoceptor agonist.
    Authors: Tannheimer S, Sorensen E, Cui Z, Kim M, Patel L, Baker W, Phillips G, Wright C, Salmon M
    J Pharmacol Exp Ther, 2014-02-10;349(1):85-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  544. CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
    Authors: Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J
    J Immunol, 2014-02-05;192(5):2449-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  545. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.
    Authors: Milwid, Jack M, Elman, Jessica, Li, Matthew, Shen, Keyue, Manrai, Arjun, Gabow, Aaron, Yarmush, Joshua, Jiao, Yunxin, Fletcher, Anne, Lee, Jungwoo, Cima, Michael, Yarmush, Martin L, Parekkadan, Biju
    Mol Ther, 2014-02-05;22(5):999-1007.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  546. TNF-alpha induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-kappaB activation in osteoblast-like MC3T3-E1 cells.
    Authors: Tsai C, Chen W, Hsieh H, Chi P, Hsiao L, Yang C
    J Biomed Sci, 2014-02-05;21(0):12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  547. Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity.
    Authors: Morlino G, Barreiro O, Baixauli F, Robles-Valero J, Gonzalez-Granado J, Villa-Bellosta R, Cuenca J, Sanchez-Sorzano C, Veiga E, Martin-Cofreces N, Sanchez-Madrid F
    Mol Cell Biol, 2014-02-03;34(8):1412-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  548. TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways.
    Authors: Lo H, Lai T, Li C, Wu W
    Acta Pharmacol Sin, 2014-02-03;35(3):339-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  549. Absence of a role for interleukin-13 in inflammatory bowel disease.
    Authors: Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, Hoque S, Ghanbari A, Joe-Njoku I, Giuffrida P, Rovedatti L, Geginat J, Corazza G, MacDonald T
    Eur J Immunol, 2014-02-01;44(2):370-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  550. Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA.
    Authors: Chiliveru S, Rahbek S, Jensen S, Jorgensen S, Nissen S, Christiansen S, Mogensen T, Jakobsen M, Iversen L, Johansen C, Paludan S
    J Immunol, 2014-01-31;192(5):2395-404.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  551. Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes.
    Authors: Haseeb A, Makki M, Haqqi T
    J Biol Chem, 2014-01-27;289(10):6877-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  552. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014-01-23;23(6):605-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  553. TRAIL/DR5 signaling promotes macrophage foam cell formation by modulating scavenger receptor expression.
    Authors: Liu F, Wu X, Zhang Y, Wang Y, Jiang F
    PLoS ONE, 2014-01-22;9(1):e87059.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  554. Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells.
    Authors: Liu C, Chen X, Yang L, Kisseleva T, Brenner D, Seki E
    J Biol Chem, 2014-01-21;289(10):7082-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  555. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
    Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
    J Exp Med, 2014-01-20;211(2):263-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  556. Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy.
    Authors: Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari B, Jha K, Barhanpurkar A, Wani M, Roy S, Mabalirajan U, Ghosh B, Agrawal A
    EMBO J, 2014-01-15;33(9):994-1010.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  557. Durable remission of renal cell carcinoma in conjuncture with graft versus host disease following allogeneic stem cell transplantation and donor lymphocyte infusion: rule or exception?
    Authors: van Bergen, Cornelis, Verdegaal, Elisabet, Honders, M Wilhel, Hoogstraten, Conny, Steijn-van Tol, A Q M Je, de Quartel, Linda, de Jong, Joan, Meyering, Maaike, Falkenburg, J H Fred, Griffioen, Marieke, Osanto, Susanne
    PLoS ONE, 2014-01-15;9(1):e85198.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  558. TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.
    Authors: Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H
    Proc Natl Acad Sci U S A, 2014-01-13;111(4):1509-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  559. Pharmacologic IKK/NF-kappaB inhibition causes antigen presenting cells to undergo TNFalpha dependent ROS-mediated programmed cell death.
    Authors: Tilstra J, Gaddy D, Zhao J, Dave S, Niedernhofer L, Plevy S, Robbins P
    Sci Rep, 2014-01-10;4(0):3631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  560. IDO-independent suppression of T cell effector function by IFN-gamma-licensed human mesenchymal stromal cells.
    Authors: Chinnadurai R, Copland I, Patel S, Galipeau J
    J Immunol, 2014-01-08;192(4):1491-501.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  561. Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.
    Authors: Suzuki, Hitoshi, Raska, Milan, Yamada, Koshi, Moldoveanu, Zina, Julian, Bruce A, Wyatt, Robert J, Tomino, Yasuhiko, Gharavi, Ali G, Novak, Jan
    J Biol Chem, 2014-01-07;289(8):5330-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  562. High activities of BACE1 in brains with mild cognitive impairment.
    Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y
    Am J Pathol, 2014-01-01;184(1):141-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay, Cell Culture
  563. TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
    Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
    Nat Commun, 2014-01-01;5(0):3199.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  564. Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation.
    Authors: Narayanan R, Yepuru M, Coss C, Wu Z, Bauler M, Barrett C, Mohler M, Wang Y, Kim J, Snyder L, He Y, Levy N, Miller D, Dalton J
    PLoS ONE, 2013-12-26;8(12):e83380.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  565. The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
    Authors: Fiorcari S, Brown W, McIntyre B, Estrov Z, Maffei R, O'Brien S, Sivina M, Hoellenriegel J, Wierda W, Keating M, Ding W, Kay N, Lannutti B, Marasca R, Burger J
    PLoS ONE, 2013-12-23;8(12):e83830.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  566. Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.
    Authors: Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H
    PLoS ONE, 2013-12-20;8(12):e82586.
    Species: Human
    Sample Types: N/A
  567. Tumor necrosis factor stimulates osteoclastogenesis from human bone marrow cells under hypoxic conditions.
    Authors: Nomura T, Aoyama M, Waguri-Nagaya Y, Goto Y, Suzuki M, Miyazawa K, Asai K, Goto S
    Exp Cell Res, 2013-12-17;321(2):167-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  568. Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.
    Authors: Dalli, Jesmond, Norling, Lucy V, Montero-Melendez, Trinidad, Federici Canova, Donata, Lashin, Hazem, Pavlov, Anton M, Sukhorukov, Gleb B, Hinds, Charles, Perretti, Mauro
    EMBO Mol Med, 2013-12-15;6(1):27-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  569. Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Jones K, Johansen B
    PLoS ONE, 2013-12-12;8(12):e83555.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  570. A composite model of the human postcapillary venule for investigation of microvascular leukocyte recruitment.
    Authors: Lauridsen H, Pober J, Gonzalez A
    FASEB J, 2013-12-02;28(3):1166-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  571. p38-Mediated phosphorylation of Eps15 endocytic adaptor protein.
    Authors: Zhou Y, Tanaka T, Sugiyama N, Yokoyama S, Kawasaki Y, Sakuma T, Ishihama Y, Saiki I, Sakurai H
    FEBS Lett, 2013-11-21;588(1):131-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  572. Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.
    Authors: Cucchiarini M, Madry H, Terwilliger E
    J Cell Mol Med, 2013-11-17;18(1):115-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  573. NF-kappaB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma.
    Authors: McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, Benveniste E, Nozell S
    PLoS ONE, 2013-11-11;8(11):e78728.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  574. Influence of proinflammatory stimuli on the expression of vascular ribonuclease 1 in endothelial cells.
    Authors: Gansler J, Preissner K, Fischer S
    FASEB J, 2013-10-30;28(2):752-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  575. Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation.
    Authors: Duverger, Alexandr, Wolschendorf, Frank, Anderson, Joshua C, Wagner, Frederic, Bosque, Alberto, Shishido, Takao, Jones, Jennifer, Planelles, Vicente, Willey, Christop, Cron, Randall, Kutsch, Olaf
    J Virol, 2013-10-23;88(1):364-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  576. The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes.
    Authors: Mercier S, Donaghy H, Botting R, Turville S, Harman A, Nasr N, Ji H, Kusebauch U, Mendoza L, Shteynberg D, Sandgren K, Simpson R, Moritz R, Cunningham A
    PLoS Pathog, 2013-10-17;9(10):e1003700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  577. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays.
    Authors: Todd J, Simpson P, Estis J, Torres V, Wub A
    Cytokine, 2013-10-12;64(3):660-5.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA (Standard)
  578. Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection.
    Authors: Fraietta J, Mueller Y, Yang G, Boesteanu A, Gracias D, Do D, Hope J, Kathuria N, McGettigan S, Lewis M, Giavedoni L, Jacobson J, Katsikis P
    PLoS Pathog, 2013-10-10;9(10):e1003658.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  579. Long-term incubation with proteasome inhibitors (PIs) induces IkappaBalpha degradation via the lysosomal pathway in an IkappaB kinase (IKK)-dependent and IKK-independent manner.
    Authors: Lee K, Jeong J, Yoo C
    J Biol Chem, 2013-10-01;288(45):32777-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  580. Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis.
    Authors: Han B, You B, Park W
    Oncol Rep, 2013-09-20;30(6):2999-3005.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  581. Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma.
    Authors: Zheng Y, McFarland B, Drygin D, Yu H, Bellis S, Kim H, Bredel M, Benveniste E
    Clin Cancer Res, 2013-09-13;19(23):6484-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  582. Novel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function.
    Authors: Tsubota Y, Frey J, Raines E
    J Leukoc Biol, 2013-09-04;95(1):191-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  583. Magnolol inhibits migration of vascular smooth muscle cells via cytoskeletal remodeling pathway to attenuate neointima formation.
    Authors: Karki R, Kim S, Kim D
    Exp Cell Res, 2013-07-29;319(20):3238-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  584. Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.
    Authors: Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Muller I
    Eur J Immunol, 2013-07-23;43(10):2741-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  585. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics.
    Authors: Rapicavoli N, Qu K, Zhang J, Mikhail M, Laberge R, Chang H
    Elife, 2013-07-23;2(0):e00762.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  586. Tumor cell-macrophage interactions increase angiogenesis through secretion of EMMPRIN.
    Authors: Amit-Cohen B, Rahat M, Rahat M
    Front Physiol, 2013-07-12;4(0):178.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  587. A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells.
    Authors: Cai, Minchao, Wu, Jing, Mao, Chaoming, Ren, Jianmin, Li, Pu, Li, Xiao, Zhong, Jiuchang, Xu, Chundi, Zhou, Tong
    J Transl Med, 2013-04-29;11(0):103.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  588. Interferon-beta induces distinct gene expression response patterns in human monocytes versus T cells.
    Authors: Henig N, Avidan N, Mandel I, Staun-Ram E, Ginzburg E, Paperna T, Pinter R, Miller A
    PLoS ONE, 2013-04-23;8(4):e62366.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  589. Comparison of drug and cell-based delivery: engineered adult mesenchymal stem cells expressing soluble tumor necrosis factor receptor II prevent arthritis in mouse and rat animal models.
    Authors: Liu L, Wang G, Hendricks K, Lee K, Bohnlein E, Junker U, Mosca J
    Stem Cells Transl Med, 2013-04-16;2(5):362-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  590. Attenuated TGF-beta1 responsiveness of dendritic cells and their precursors in atopic dermatitis.
    Authors: Peng W, Maintz L, Allam J, Novak N
    Eur J Immunol, 2013-04-09;43(5):1374-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  591. Tumor necrosis factor alpha-induced microRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-kappaB signaling.
    Authors: Trenkmann M, Brock M, Gay R, Michel B, Gay S, Huber L
    Arthritis Rheum, 2013-04-01;65(4):916-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  592. The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography.
    Authors: Melo, Rossana, Paganoti, Guillher, Dvorak, Ann M, Weller, Peter F
    PLoS ONE, 2013-03-26;8(3):e59578.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  593. Role and regulation of PDGFRalpha signaling in liver development and regeneration.
    Authors: Awuah P, Nejak-Bowen K, Monga S
    Am J Pathol, 2013-03-23;182(5):1648-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  594. Outer membrane vesicles derived from Escherichia coli up-regulate expression of endothelial cell adhesion molecules in vitro and in vivo.
    Authors: Kim J, Yoon Y, Lee J, Choi E, Yi N, Park K, Park J, Lotvall J, Kim Y, Gho Y
    PLoS ONE, 2013-03-14;8(3):e59276.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  595. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013-03-13;190(8):4196-204.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  596. Integration and regression of implanted engineered human vascular networks during deep wound healing.
    Authors: Hanjaya-Putra D, Shen Y, Wilson A, Fox-Talbot K, Khetan S, Burdick J, Steenbergen C, Gerecht S
    Stem Cells Transl Med, 2013-03-13;2(4):297-306.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  597. Protein carbamylation predicts mortality in ESRD.
    Authors: Koeth R, Kalantar-Zadeh K, Wang Z, Fu X, Tang W, Hazen S
    2013-02-21;0(0):.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  598. IFN-alpha induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells.
    Authors: Mohanram V, Skold A, Bachle S, Pathak S, Spetz A
    J Immunol, 2013-02-20;190(7):3346-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  599. TCR-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac, and myosin IIA.
    Authors: Manes, Thomas D, Pober, Jordan S
    J Immunol, 2013-02-18;190(7):3079-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  600. Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation.
    Authors: Johnston A, Fritz Y, Dawes S, Diaconu D, Al-Attar P, Guzman A, Chen C, Fu W, Gudjonsson J, McCormick T, Ward N
    J Immunol, 2013-01-28;190(5):2252-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  601. 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.
    Authors: Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem G, Singh S, Dinda A, Biswal S, Agrawal A, Ghosh B
    Sci Rep, 2013-01-01;3(0):1540.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  602. Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
    Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
    J Biol Chem, 2012-11-26;288(3):1953-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  603. MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuli.
    Authors: Sheng Y, Triyana S, Wang R, Das I, Gerloff K, Florin T, Sutton P, McGuckin M
    Mucosal Immunol, 2012-11-14;6(3):557-68.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  604. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
    Authors: Boisson B, Laplantine E, Prando C, Giliani S, Israelsson E, Xu Z, Abhyankar A, Israel L, Trevejo-Nunez G, Bogunovic D, Cepika A, MacDuff D, Chrabieh M, Hubeau M, Bajolle F, Debre M, Mazzolari E, Vairo D, Agou F, Virgin H, Bossuyt X, Rambaud C, Facchetti F, Bonnet D, Quartier P, Fournet J, Pascual V, Chaussabel D, Notarangelo L, Puel A, Israel A, Casanova J, Picard C
    Nat Immunol, 2012-10-28;13(12):1178-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  605. In vivo modulation of the inflammatory response by nonsteroidal antiinflammatory drug-related compounds that trigger L-selectin shedding.
    Authors: Herrera-Garcia A, Dominguez-Luis M, Arce-Franco M, Lopez-Fernandez J, Feria M, Barreiro O, Sanchez-Madrid F, Diaz-Gonzalez F
    Eur J Immunol, 2012-10-26;43(1):55-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  606. Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.
    Authors: Hutter, Caroline, Kauer, Max, Simonitsch-Klupp, Ingrid, Jug, Gunhild, Schwentner, Raphaela, Leitner, Judith, Bock, Peter, Steinberger, Peter, Bauer, Wolfgang, Carlesso, Nadia, Minkov, Milen, Gadner, Helmut, Stingl, Georg, Kovar, Heinrich, Kriehuber, Ernst
    Blood, 2012-10-16;120(26):5199-208.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  607. Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration.
    Authors: Rossi E, Sanz-Rodriguez F, Eleno N, Duwell A, Blanco F, Langa C, Botella L, Cabanas C, Lopez-Novoa J, Bernabeu C
    Blood, 2012-10-16;121(2):403-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  608. Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.
    Authors: Brusic, Ana, Hainz, Ursula, Wadleigh, Martha, Neuberg, Donna, Su, Mei, Canning, Christin, Deangelo, Daniel J, Stone, Richard, Lee, Jeng-Shi, Mulligan, Richard, Ritz, Jerome, Dranoff, Glenn, Sasada, Tetsuro, Wu, Catherin
    Oncoimmunology, 2012-10-01;1(7):1095-1103.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  609. Mycobacterium tuberculosis infection and tissue factor expression in macrophages.
    Authors: Kothari H, Rao L, Vankayalapati R, Pendurthi U
    PLoS ONE, 2012-09-24;7(9):e45700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  610. AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications: Evidence for IL-12 intracrine activity in DC.
    Authors: You C, Shi M, Liu Y, Cao M, Luo R, Hermonat P
    Oncoimmunology, 2012-09-01;1(6):847-855.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  611. Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation.
    Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K
    Infect Immun, 2012-08-13;80(11):3795-803.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  612. Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER).
    Authors: Satomi-Kobayashi S, Kinugasa M, Kobayashi R, Hatakeyama K, Kurogane Y, Ishida T, Emoto N, Asada Y, Takai Y, Hirata K, Rikitake Y
    J Biol Chem, 2012-07-09;287(36):30336-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  613. The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells.
    Authors: Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC
    PLoS ONE, 2012-06-22;7(6):e38721.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  614. Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas.
    J. Invest. Dermatol., 2012-06-21;132(11):2642-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  615. The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase.
    Authors: Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD
    J. Biol. Chem., 2012-06-11;287(31):25964-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  616. Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.
    J. Invest. Dermatol., 2012-06-07;132(11):2593-600.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  617. A20/TNFAIP3 inhibits NF-kappaB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.
    Authors: Sakakibara S, Espigol-Frigole G, Gasperini P, Uldrick T, Yarchoan R, Tosato G
    Oncogene, 2012-04-23;32(10):1223-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  618. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012-04-18;7(4):e34965.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  619. Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
    Authors: Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M
    Eur. J. Immunol., 2012-04-01;42(4):936-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  620. Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells: A three phase experimental procedure.
    Authors: Wilde S, Geiger C, Milosevic S, Mosetter B, Eichenlaub S, Schendel D
    Oncoimmunology, 2012-03-01;1(2):129-140.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  621. Constitutive expression of inter-alpha-inhibitor (IalphaI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.
    Authors: Zhang S, He H, Day AJ, Tseng SC
    J. Biol. Chem., 2012-02-20;287(15):12433-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  622. Daily exposure to dust alters innate immunity.
    Authors: Sahlander K, Larsson K, Palmberg L
    PLoS ONE, 2012-02-15;7(2):e31646.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  623. Kinome-wide functional genomics screen reveals a novel mechanism of TNFα-induced nuclear accumulation of the HIF-1α transcription factor in cancer cells.
    Authors: Schoolmeesters A, Brown DD, Fedorov Y
    PLoS ONE, 2012-02-15;7(2):e31270.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  624. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency.
    Authors: Sancho-Shimizu V, Perez de Diego R, Lorenzo L, Halwani R, Alangari A, Israelsson E, Fabrega S, Cardon A, Maluenda J, Tatematsu M, Mahvelati F, Herman M, Ciancanelli M, Guo Y, AlSum Z, Alkhamis N, Al-Makadma AS, Ghadiri A, Boucherit S, Plancoulaine S, Picard C, Rozenberg F, Tardieu M, Lebon P, Jouanguy E, Rezaei N, Seya T, Matsumoto M, Chaussabel D, Puel A, Zhang SY, Abel L, Al-Muhsen S, Casanova JL
    J. Clin. Invest., 2011-11-21;121(12):4889-902.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  625. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
    Gene Ther, 2011-11-10;19(10):1035-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  626. Expression and regulation of CCL15 by human airway smooth muscle cells.
    Authors: Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q
    Clin. Exp. Allergy, 2011-11-09;42(1):85-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  627. Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1.
    Authors: Wang R, Jaw JJ, Jaw J, Stutzman NC, Stutzman N, Zou Z, Sun PD
    J Leukoc Biol, 2011-11-01;91(2):299-309.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  628. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
    Authors: Ramirez-Carrozzi V, Sambandam A, Luis E
    Nat. Immunol., 2011-10-12;12(12):1159-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  629. Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.
    Authors: Cross SA, Cook DR, Chi AW, Vance PJ, Kolson LL, Wong BJ, Jordan-Sciutto KL, Kolson DL
    J. Immunol., 2011-10-05;187(10):5015-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  630. Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
    Authors: Beck B, Dorfel D, Lichtenegger FS, Geiger C, Lindner L, Merk M, Schendel DJ, Subklewe M
    J Transl Med, 2011-09-13;9(0):151.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  631. BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium.
    Authors: Helbing T, Rothweiler R, Ketterer E, Goetz L, Heinke J, Grundmann S, Duerschmied D, Patterson C, Bode C, Moser M
    Blood, 2011-09-07;118(18):5040-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  632. Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.
    Authors: Carrier Y, Ma HL, Ramon HE, Napierata L, Small C, O'Toole M, Young DA, Fouser LA, Nickerson-Nutter C, Collins M, Dunussi-Joannopoulos K, Medley QG
    J. Invest. Dermatol., 2011-09-01;131(12):2428-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  633. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes.
    Authors: Liu F, Chen HY, Huang XR, Chung AC, Zhou L, Fu P, Szalai AJ, Lan HY
    Diabetologia, 2011-07-09;54(10):2713-23.
    Applications: ELISA (Standard)
  634. Monocytic microparticles activate endothelial cells in an IL-1{beta}-dependent manner.
    Authors: Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N
    Blood, 2011-06-23;118(8):2366-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  635. Cadherin-11 regulates fibroblast inflammation.
    Authors: Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB
    Proc. Natl. Acad. Sci. U.S.A., 2011-05-02;108(20):8402-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  636. IL-17A and TNF-alpha Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro.
    Authors: Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS
    J. Immunol., 2011-01-31;186(5):3197-205.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  637. IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression.
    Authors: Johnston A, Xing X, Guzman AM, Riblett M, Loyd CM, Ward NL, Wohn C, Prens EP, Wang F, Maier LE, Kang S, Voorhees JJ, Elder JT, Gudjonsson JE
    J. Immunol., 2011-01-17;186(4):2613-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  638. T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma.
    Authors: Corrigan CJ, Wang W, Meng Q, Fang C, Wu H, Reay V, Lv Z, Fan Y, An Y, Wang YH, Liu YJ, Lee TH, Ying S
    Proc. Natl. Acad. Sci. U.S.A., 2011-01-04;108(4):1579-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  639. Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil Activation.
    Authors: Jerke U, Rolle S, Dittmar G, Bayat B, Santoso S, Sporbert A, Luft F, Kettritz R
    J. Biol. Chem., 2010-12-30;286(9):7070-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  640. Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction.
    Authors: Estrada-Gutierrez G, Cappello RE, Mishra N, Romero R, Strauss JF, Walsh SW
    Am. J. Pathol., 2010-12-23;178(1):451-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  641. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.
    Authors: Shin HS, Xu F, Bagchi A, Herrup E, Wilhelmsen K
    J. Immunol., 2010-12-17;186(2):1119-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  642. Focal increases of fetal macrophages in placentas from pregnancies with histological chorioamnionitis: potential role of fibroblast monocyte chemotactic protein-1.
    Authors: Toti P, Arcuri F, Tang Z, Schatz F, Zambrano E, Mor G, Niven-Fairchild T, Abrahams VM, Krikun G, Lockwood CJ, Guller S
    Am. J. Reprod. Immunol., 2010-11-19;65(5):470-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  643. HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies.
    Authors: Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C
    J. Virol., 2010-11-17;85(2):1077-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  644. Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.
    Authors: Xu H, Wang X, Pahar B
    J. Immunol., 2010-11-08;185(12):7340-8.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  645. Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.
    Authors: Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D
    J. Immunol., 2010-10-13;185(10):6306-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  646. Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration.
    Authors: Johnson LA, Jackson DG
    Int. Immunol., 2010-08-25;22(10):839-49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  647. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010-08-09;185(6):3677-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  648. LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism.
    Authors: Tiller G, Laumen H, Fischer-Posovszky P, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H
    Int J Obes (Lond), 2010-06-15;35(2):208-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  649. IFN-gamma generates maturation-arrested dendritic cells that induce T cell hyporesponsiveness independent of Foxp3+ T-regulatory cell generation.
    Authors: Rojas D, Krishnan R
    Immunol. Lett., 2010-05-24;132(1):31-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  650. Evidence for altered Wnt signaling in psoriatic skin.
    Authors: Gudjonsson JE, Johnston A, Stoll SW
    J. Invest. Dermatol., 2010-04-08;130(7):1849-59.
    Species: Human
    Sample Types: Whole Cells
  651. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
    Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Immunol., 2010-03-31;184(9):4880-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  652. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
    Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
    J. Immunol., 2010-03-24;184(0):5263-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  653. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
    Authors: Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R
    Eur. J. Immunol., 2009-12-01;39(12):3570-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  654. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients.
    Authors: Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK
    Immunol. Lett., 2009-11-04;127(2):150-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  655. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2009-10-07;3(1):40-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  656. TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses.
    Authors: Duraisingham SS, Hornig J, Gotch F, Patterson S
    J. Immunol., 2009-07-22;183(4):2242-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  657. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 2009-07-15;284(36):24035-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  658. Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases.
    Authors: Margulis A, Nocka KH, Brennan AM, Deng B, Fleming M, Goldman SJ, Kasaian MT
    J. Immunol., 2009-07-10;183(3):1739-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  659. Soluble decoy receptor 3 modulates the survival and formation of osteoclasts from multiple myeloma bone disease patients.
    Authors: Colucci S, Brunetti G, Mori G, Oranger A, Centonze M, Mori C, Cantatore FP, Tamma R, Rizzi R, Liso V, Zallone A, Grano M
    Leukemia, 2009-07-09;23(11):2139-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  660. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.
    Authors: Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F
    Nat. Immunol., 2009-07-05;10(8):857-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  661. Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
    Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
    Clin. Immunol., 2009-06-25;133(1):27-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  662. Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
    Authors: Dave SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE
    J. Leukoc. Biol., 2009-05-19;86(3):633-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  663. The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
    Authors: Kato N, Yuzawa Y, Kosugi T
    J. Am. Soc. Nephrol., 2009-05-14;20(7):1565-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  664. Inhibition of double-stranded RNA-induced TSLP in human keratinocytes by glucocorticoids.
    Authors: Le TA, Takai T, Kinoshita H, Suto H, Ikeda S, Okumura K, Ogawa H
    Allergy, 2009-03-27;64(8):1231-2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  665. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.
    Authors: Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C
    Bone, 2009-03-02;44(6):1143-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  666. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  667. Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines.
    Authors: Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ
    Invest. Ophthalmol. Vis. Sci., 2009-01-17;50(6):2702-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  668. Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.
    Authors: Mabilleau G, Sabokbar A
    PLoS ONE, 2009-01-12;4(1):e4173.
    Species: Human
    Sample Types:
  669. Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease.
    Authors: Miller M, Cho JY, Pham A, Ramsdell J, Broide DH
    J. Immunol., 2009-01-01;182(1):684-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  670. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
    Authors: Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S
    J. Exp. Med., 2008-12-29;206(1):249-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  671. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
    Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
    J. Allergy Clin. Immunol., 2008-12-03;123(1):179-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  672. Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation.
    Authors: Hama S, Takeichi O, Fujisaki K, Tanabe N, Maeno M, Ochiai K
    Clin. Exp. Immunol., 2008-12-01;154(3):384-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  673. Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.
    Authors: Kwan Tat S, Pelletier JP, Amiable N, Boileau C, Lajeunesse D, Duval N, Martel-Pelletier J
    Arthritis Rheum., 2008-12-01;58(12):3820-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  674. Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
    Authors: Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H
    Clin. Exp. Immunol., 2008-11-26;155(2):266-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  675. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
    Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
    Circ. Res., 2008-11-20;104(1):60-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  676. Ectopic expression of interleukin-1 receptor type II enhances cell migration through activation of the pre-interleukin 1alpha pathway.
    Authors: Chang SY, Su PF, Lee TC
    Cytokine, 2008-11-20;45(1):32-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  677. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis.
    Authors: Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M
    J. Invest. Dermatol., 2008-10-02;129(3):650-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  678. Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells.
    Authors: Secchiero P, Melloni E, Corallini F, Beltrami AP, Alviano F, Milani D, D'Aurizio F, di Iasio MG, Cesselli D, Bagnara GP, Zauli G
    Stem Cells, 2008-09-04;26(11):2955-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  679. A novel method to establish microglia-free astrocyte cultures: comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia.
    Authors: Crocker SJ, Frausto RF, Whitton JL, Milner R
    Glia, 2008-08-15;56(0):1187-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  680. Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma.
    Authors: Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H
    Int. J. Oncol., 2008-08-01;33(2):297-308.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  681. IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells.
    Authors: Gerber SA, Pober JS
    J. Immunol., 2008-07-15;181(2):1052-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  682. Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation.
    Authors: Barbaroux JB, Beleut M, Brisken C, Mueller CG, Groves RW
    J. Immunol., 2008-07-15;181(2):1103-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  683. Effect of fudosteine on mucin production.
    Authors: Rhee CK, Kang CM, You MB, Yoon HK, Kim YK, Kim KH, Moon HS, Park SH, Song JS
    Eur. Respir. J., 2008-06-25;32(5):1195-202.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  684. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils.
    Authors: Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H
    J. Allergy Clin. Immunol., 2008-06-01;121(6):1484-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  685. IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation.
    Authors: Jasny E, Eisenblatter M, Matz-Rensing K, Tenner-Racz K, Tenbusch M, Schrod A, Stahl-Hennig C, Moos V, Schneider T, Racz P, Uberla K, Kaup FJ, Ignatius R
    J. Immunol., 2008-05-15;180(10):6629-39.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  686. Development and validation of sandwich ELISA microarrays with minimal assay interference.
    Authors: Gonzalez RM, Seurynck-Servoss SL, Crowley SA
    J. Proteome Res., 2008-04-19;7(6):2406-14.
    Applications: ELISA (Standard)
  687. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.
    Authors: Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP
    J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  688. p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications.
    Authors: Ishitsuka K, Hideshima T, Neri P, Vallet S, Shiraishi N, Okawa Y, Shen Z, Raje N, Kiziltepe T, Ocio EM, Chauhan D, Tassone P, Munshi N, Campbell RM, Dios AD, Shih C, Starling JJ, Tamura K, Anderson KC
    Br. J. Haematol., 2008-04-07;141(5):598-606.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  689. Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.
    Authors: Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE, Detmar M, Gay S, Kyburz D
    Arthritis Rheum., 2008-04-01;58(4):1001-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  690. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
    Authors: Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
    AIDS Res. Hum. Retroviruses, 2008-03-01;24(3):453-62.
    Applications: ELISA (Standard)
  691. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
    Authors: Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R
    J. Leukoc. Biol., 2008-02-15;83(5):1181-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  692. Expression and regulation of CCR1 by airway smooth muscle cells in asthma.
    Authors: Joubert P, Lajoie-Kadoch S, Welman M, Dragon S, Letuvee S, Tolloczko B, Halayko AJ, Gounni AS, Maghni K, Hamid Q
    J. Immunol., 2008-01-15;180(2):1268-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  693. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007-12-21;111(8):4096-105.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  694. Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice.
    Authors: Dahm F, Bielawska A, Nocito A, Georgiev P, Szulc ZM, Bielawski J, Jochum W, Dindo D, Hannun YA, Clavien PA
    Br. J. Cancer, 2007-11-20;98(1):98-105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  695. IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response.
    Authors: Rao DA, Tracey KJ, Pober JS
    J. Immunol., 2007-11-15;179(10):6536-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  696. Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells.
    Authors: Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G, Zauli G
    Blood, 2007-11-13;111(3):1287-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  697. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines.
    Authors: Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA
    Clin. Chem., 2007-11-01;53(11):2010-2.
    Applications: ELISA (Standard)
  698. Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells.
    Authors: Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK, Kim EC
    Clin. Exp. Immunol., 2007-10-09;150(3):567-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  699. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007-09-21;53(11):1990-5.
    Applications: ELISA (Standard)
  700. Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood.
    Authors: Hall JP, Kurdi Y, Hsu S, Cuozzo J, Liu J, Telliez JB, Seidl KJ, Winkler A, Hu Y, Green N, Askew GR, Tam S, Clark JD, Lin LL
    J. Biol. Chem., 2007-09-11;282(46):33295-304.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  701. Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
    Authors: Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS
    J. Biol. Chem., 2007-08-24;282(43):31643-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  702. Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis.
    Authors: Wosik K, Cayrol R, Dodelet-Devillers A, Berthelet F, Bernard M, Moumdjian R, Bouthillier A, Reudelhuber TL, Prat A
    J. Neurosci., 2007-08-22;27(34):9032-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  703. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.
    Authors: Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE
    J. Immunol., 2007-08-01;179(3):1872-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  704. Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques.
    Authors: Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW
    Transplantation, 2007-07-27;84(2):196-206.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  705. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells.
    Authors: Kato A, Favoreto S, Avila PC, Schleimer RP
    J. Immunol., 2007-07-15;179(2):1080-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  706. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates.
    Authors: Luty WH, Rodeberg D, Parness J, Vyas YM
    J. Immunol., 2007-07-15;179(2):819-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  707. Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis.
    Authors: Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C
    J. Leukoc. Biol., 2007-07-05;82(4):946-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  708. Calcineurin modulates the catabolic and anabolic activity of chondrocytes and participates in the progression of experimental osteoarthritis.
    Authors: Yoo SA, Park BH, Yoon HJ, Lee JY, Song JH, Kim HA, Cho CS, Kim WU
    Arthritis Rheum., 2007-07-01;56(7):2299-311.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  709. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
    Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
    J. Clin. Invest., 2007-07-01;117(7):1951-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  710. Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.
    Authors: Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A
    J. Immunol., 2007-06-15;178(12):8064-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  711. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork.
    Authors: Kelley MJ, Rose AY, Song K, Chen Y, Bradley JM, Rookhuizen D, Acott TS
    Invest. Ophthalmol. Vis. Sci., 2007-06-01;48(6):2634-43.
    Species: Human, Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  712. The role of vascular cell adhesion molecule 1/ very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium.
    Authors: Silverman MD, Haas CS, Rad AM, Arbab AS, Koch AE
    Arthritis Rheum., 2007-06-01;56(6):1817-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  713. Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease.
    Authors: Zhang K, Shan L, Rahman MS, Unruh H, Halayko AJ, Gounni AS
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007-05-18;293(2):L375-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  714. IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.
    Authors: Wolk K, Witte E, Hoffmann U, Doecke WD, Endesfelder S, Asadullah K, Sterry W, Volk HD, Wittig BM, Sabat R
    J. Immunol., 2007-05-01;178(9):5973-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  715. IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis.
    Authors: Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G
    J. Immunol., 2007-05-01;178(9):5957-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  716. Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
    Authors: Dambacher J, Beigel F, Seiderer J, Haller D, Goke B, Auernhammer CJ, Brand S
    Gut, 2007-04-20;56(9):1257-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  717. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells.
    Authors: Tacke F, Gabele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Scholmerich J, Schnabl B
    Dig. Dis. Sci., 2007-04-06;52(12):3404-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  718. LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes.
    Authors: Kang YM, Kim SY, Kang JH
    Arthritis Rheum., 2007-04-01;56(4):1106-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  719. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression.
    Authors: Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H
    Int. J. Oncol., 2007-04-01;30(4):977-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  720. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers.
    Authors: van Grevenstein WM, Hofland LJ, van Rossen ME, van Koetsveld PM, Jeekel J, van Eijck CH
    Dig. Dis. Sci., 2007-03-30;52(10):2775-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  721. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.
    Authors: Ponte AL, Marais E, Gallay N, Langonne A, Delorme B, Herault O, Charbord P, Domenech J
    Stem Cells, 2007-03-29;25(7):1737-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  722. Regulation of neuronal pituitary adenylate cyclase-activating polypeptide expression during culture of guinea-pig cardiac ganglia.
    Authors: Girard BM, Young BA, Buttolph TR, White SL, Parsons RL
    Neuroscience, 2007-03-23;146(2):584-93.
    Species: Guinea Pig
    Sample Types: Whole Cells
    Applications: Bioassay
  723. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression.
    Authors: Brechter AB, Lerner UH
    Arthritis Rheum., 2007-03-01;56(3):910-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  724. CD28-mediated regulation of multiple myeloma cell proliferation and survival.
    Authors: Bahlis NJ, King AM, Kolonias D, Carlson LM, Liu HY, Hussein MA, Terebelo HR, Byrne GE, Levine BL, Boise LH, Lee KP
    Blood, 2007-02-20;109(11):5002-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  725. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
    Authors: Sa SM, Valdez PA, Wu J
    J. Immunol., 2007-02-15;178(4):2229-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  726. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
    Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
    Blood, 2007-02-08;109(10):4272-9.
    Applications: ELISA (Standard)
  727. Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact cultures.
    Authors: Sawant KV, McMurray DN
    Infect. Immun., 2007-02-05;75(4):1870-7.
    Applications: ELISA (Standard)
  728. The F11 receptor (F11R/JAM-A) in atherothrombosis: overexpression of F11R in atherosclerotic plaques.
    Authors: Babinska A, Azari BM, Salifu MO, Liu R, Jiang XC, Sobocka MB, Boo D, Al Khoury G, Deitch JS, Marmur JD, Ehrlich YH, Kornecki E
    Thromb. Haemost., 2007-02-01;97(2):272-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  729. Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum.
    Authors: Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A
    Kidney Int., 2007-01-17;71(6):514-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  730. IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.
    Authors: Dame TM, Orenzoff BL, Palmer LE, Furie MB
    J. Immunol., 2007-01-15;178(2):1172-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  731. Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells.
    Authors: Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE, Baird AW
    Vet. Immunol. Immunopathol., 2007-01-09;116(1):59-68.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  732. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators.
    Authors: Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C
    Crit. Care Med., 2007-01-01;35(1):199-206.
    Species: Bovine, Human
    Sample Types: Whole Cells
    Applications: Bioassay
  733. Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.
    Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2007-01-01;210(1):192-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  734. Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells.
    Authors: Pietila TE, Veckman V, Lehtonen A, Lin R, Hiscott J, Julkunen I
    J. Immunol., 2007-01-01;178(1):253-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  735. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
    Authors: Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
    AIDS, 2007;21(10):1263-72.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  736. Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1.
    Authors: Lee SY, Cherla RP, Tesh VL
    Infect. Immun., 2006-12-28;75(3):1291-302.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  737. SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration.
    Authors: Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R
    J. Leukoc. Biol., 2006-12-18;81(3):748-56.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  738. Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis.
    Authors: Wan B, Nie H, Liu A, Feng G, He D, Xu R, Zhang Q, Dong C, Zhang JZ
    J. Immunol., 2006-12-15;177(12):8844-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  739. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006-12-01;177(11):7665-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  740. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006-11-20;203(12):2763-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  741. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
    Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
    Glia, 2006-11-01;54(6):619-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  742. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.
    Authors: Schreiber TH, Shinder V, Cain DW, Alon R, Sackstein R
    Blood, 2006-10-12;109(4):1381-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  743. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
    Authors: Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA
    Exp. Hematol., 2006-10-01;34(10):1312-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  744. Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.
    Authors: Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L
    J. Endocrinol., 2006-10-01;191(1):65-81.
    Species: Hamster
    Sample Types: Whole Cells
    Applications: Bioassay
  745. Spatial compartmentalization of tumor necrosis factor (TNF) receptor 1-dependent signaling pathways in human airway smooth muscle cells. Lipid rafts are essential for TNF-alpha-mediated activation of RhoA but dispensable for the activation of the NF-kappaB and MAPK pathways.
    Authors: Hunter I, Nixon GF
    J. Biol. Chem., 2006-09-18;281(45):34705-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  746. The ascochlorin derivative, AS-6, inhibits TNF-alpha-induced adhesion molecule and chemokine expression in rat vascular smooth muscle cells.
    Authors: Park KG, Lee KM, Magae J, Kim YN, Lee KU, Lee IK
    Life Sci., 2006-09-01;80(2):120-6.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  747. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
    Authors: Ebert EC, Mehta V
    Cell. Immunol., 2006-08-17;241(1):7-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  748. Sepsis and pathophysiology of anthrax in a nonhuman primate model.
    Authors: Stearns-Kurosawa DJ, Lupu F, Taylor FB, Kinasewitz G, Kurosawa S
    Am. J. Pathol., 2006-08-01;169(2):433-44.
    Applications: ELISA (Standard)
  749. Modeling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function.
    Authors: Rebelo SL, Bainbridge SE, Amel-Kashipaz MR, Radford PM, Powell RJ, Todd I, Tighe PJ
    Arthritis Rheum., 2006-08-01;54(8):2674-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  750. Dendritic cells can turn CD4+ T lymphocytes into vascular endothelial growth factor-carrying cells by intercellular neuropilin-1 transfer.
    Authors: Bourbie-Vaudaine S, Blanchard N, Hivroz C, Romeo PH
    J. Immunol., 2006-08-01;177(3):1460-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  751. Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha.
    Authors: Daryadel A, Grifone RF, Simon HU, Yousefi S
    J. Biol. Chem., 2006-07-21;281(37):27653-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  752. Differential survival of leukocyte subsets mediated by synovial, bone marrow, and skin fibroblasts: site-specific versus activation-dependent survival of T cells and neutrophils.
    Authors: Filer A, Parsonage G, Smith E, Osborne C, Thomas AM, Curnow SJ, Rainger GE, Raza K, Nash GB, Lord J, Salmon M, Buckley CD
    Arthritis Rheum., 2006-07-01;54(7):2096-108.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  753. Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21.
    Authors: Monteleone G, Caruso R, Fina D, Peluso I, Gioia V, Stolfi C, Fantini MC, Caprioli F, Tersigni R, Alessandroni L, MacDonald TT, Pallone F
    Gut, 2006-05-08;55(12):1774-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  754. LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis.
    Authors: Edwards JR, Sun SG, Locklin R, Shipman CM, Adamopoulos IE, Athanasou NA, Sabokbar A
    Arthritis Rheum., 2006-05-01;54(5):1451-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  755. Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis.
    Authors: Makrygiannakis D, af Klint E, Catrina SB, Botusan IR, Klareskog E, Klareskog L, Ulfgren AK, Catrina AI
    Arthritis Rheum., 2006-05-01;54(5):1463-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  756. Selective regulation of IL-10 signaling and function by zymosan.
    Authors: Du Z, Kelly E, Mecklenbrauker I, Agle L, Herrero C, Paik P, Ivashkiv LB
    J. Immunol., 2006-04-15;176(8):4785-92.
    Applications: ELISA (Standard)
  757. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
    Authors: Nguyen AN, Stebbins EG, Henson M, O&amp;apos;Young G, Choi SJ, Quon D, Damm D, Reddy M, Ma JY, Haghnazari E, Kapoun AM, Medicherla S, Protter A, Schreiner GF, Kurihara N, Anderson J, Roodman GD, Navas TA, Higgins LS
    Exp. Cell Res., 2006-04-04;312(10):1909-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  758. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis.
    Authors: Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S
    J. Clin. Invest., 2006-04-01;116(4):984-95.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  759. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.
    Authors: Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH
    Mol. Cell. Biol., 2006-04-01;26(8):3071-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  760. Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells.
    Authors: Gutierrez G, Mendoza C, Zapata E, Montiel A, Reyes E, Montano LF, Lopez-Marure R
    Atherosclerosis, 2006-03-30;190(1):90-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  761. Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli.
    Authors: Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC
    Am. J. Respir. Cell Mol. Biol., 2006-03-16;35(2):165-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  762. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006-03-15;176(6):3742-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  763. Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection.
    Authors: Das S, Suarez G, Beswick EJ, Sierra JC, Graham DY, Reyes VE
    J. Immunol., 2006-03-01;176(5):3000-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  764. IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts.
    Authors: Létuvé S, Lajoie-Kadoch S, Audusseau S, Rothenberg ME, Fiset PO, Ludwig MS, Hamid Q
    J. Allergy Clin. Immunol., 2006-02-08;117(3):590-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  765. Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
    Authors: Hanabuchi S, Watanabe N, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ
    Blood, 2006-01-05;107(9):3617-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  766. Increased ENA-78 in the follicular fluid of patients with endometriosis.
    Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
    Acta Obstet Gynecol Scand, 2006-01-01;85(3):336-42.
    Applications: ELISA (Standard)
  767. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
    Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS
    Bone, 2005-12-05;38(4):497-508.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  768. Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes.
    Authors: Mortara L, Ploquin MJ, Faye A, Scott-Algara D, Vaslin B, Butor C, Hosmalin A, Barre-Sinoussi F, Diop OM, Muller-Trutwin MC
    J. Immunol. Methods, 2005-11-21;308(1):138-55.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Whole Cells
    Applications: Bioassay
  769. Phagocytosis of codeveloping megakaryocytic progenitors by dendritic cells in culture with thrombopoietin and tumor necrosis factor-alpha and its possible role in hemophagocytic syndrome.
    Authors: Saito K, Hirokawa M, Inaba K, Fukaya H, Kawabata Y, Komatsuda A, Yamashita J, Sawada K
    Blood, 2005-10-18;107(4):1366-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  770. Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis.
    Authors: Iversen PO, Wiig H
    Clin. Cancer Res., 2005-10-01;11(19):6793-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  771. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
    Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
    J. Virol., 2005-10-01;79(20):12828-39.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Whole Cells
    Applications: Bioassay
  772. Generation of feline dendritic cells derived from peripheral blood monocytes for in vivo use.
    Authors: Freer G, Matteucci D, Mazzetti P, Bozzacco L, Bendinelli M
    Clin. Diagn. Lab. Immunol., 2005-10-01;12(10):1202-8.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  773. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
    Authors: Vergne-Salle</LastName><F P</Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
    Cytokine, 2005-09-07;31(5):335-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  774. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
    Authors: Ameredes BT, Calhoun WJ
    J. Allergy Clin. Immunol., 2005-07-01;116(1):65-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  775. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K.
    Authors: Mandelin J, Li TF, Hukkanen M, Liljestrom M, Salo J, Santavirta S, Konttinen YT
    J. Rheumatol., 2005-04-01;32(4):713-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  776. Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism.
    Authors: Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D
    J. Immunol., 2005-02-15;174(4):2376-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  777. CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1.
    Authors: Yamamoto H, Nagata M, Sakamoto Y
    Ann. Allergy Asthma Immunol., 2005-02-01;94(2):292-300.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  778. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt.
    Authors: Morel J, Audo R, Hahne M, Combe B
    J. Biol. Chem., 2005-01-31;280(16):15709-18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  779. TNFalpha increases the inflammatory response to vascular balloon injury without accelerating neointimal formation.
    Authors: Miller AM, McPhaden AR, Preston A, Wadsworth RM, Wainwright CL
    Atherosclerosis, 2004-12-23;179(1):51-9.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  780. trans fatty acids and systemic inflammation in heart failure.
    Authors: Mozaffarian D, Rimm EB, King IB, Lawler RL, McDonald GB, Levy WC
    Am. J. Clin. Nutr., 2004-12-01;80(6):1521-5.
    Applications: ELISA (Standard)
  781. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004-11-22;200(11):1419-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  782. Human bronchial epithelial cells express and secrete MMP-12.
    Authors: Lavigne MC, Thakker P, Gunn J, Miyashiro JS, Wasserman AM, Wei SQ, Pelker JW
    Biochem. Biophys. Res. Commun., 2004-11-12;324(2):534-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  783. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs.
    Authors: Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, Bougras G, Muller WA, Moretta L, Munz C
    Proc. Natl. Acad. Sci. U.S.A., 2004-11-09;101(47):16606-11.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  784. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure.
    Authors: Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A
    J. Immunol., 2004-11-01;173(9):5810-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  785. TARC augments TNF-alpha-induced CTACK production in keratinocytes.
    Authors: Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M
    Exp. Dermatol., 2004-09-01;13(9):551-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  786. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
    Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
    J. Immunol., 2004-09-01;173(5):3482-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  787. Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1).
    Authors: Chopin V, Slomianny C, Hondermarck H, Le Bourhis X
    Exp. Cell Res., 2004-08-15;298(2):560-73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  788. Impact of fibronectin fragments on the transendothelial migration of HIV-infected leukocytes and the development of subendothelial foci of infectious leukocytes.
    Authors: Birdsall HH, Porter WJ, Green DM, Rubio J, Trial J, Rossen RD
    J. Immunol., 2004-08-15;173(4):2746-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  789. The effect of inflammatory cytokines on secretion of macrophage colony-stimulating factor and monocyte chemoattractant protein-1 in human granulosa cells.
    Authors: Kawano Y, Fukuda J, Itoh H, Takai N, Nasu K, Miyakawa I
    Am. J. Reprod. Immunol., 2004-08-01;52(2):124-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  790. Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes.
    Authors: Johansson MW, Lye MH, Barthel SR, Duffy AK, Annis DS, Mosher DF
    Am. J. Respir. Cell Mol. Biol., 2004-06-25;31(4):413-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  791. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
    Authors: Phillips TM
    Electrophoresis, 2004-06-01;25(10):1652-9.
  792. Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
    Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
    Biochem. J., 2004-06-01;380(0):425-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  793. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
    Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
    Immunology, 2004-06-01;112(2):274-89.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  794. KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation.
    Authors: SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, Kumar A, Feinberg MW, Chen Z, Simon DI, Luscinskas FW, Michel TM, Gimbrone MA, Garcia-Cardena G, Jain MK
    J. Exp. Med., 2004-05-10;199(10):1305-15.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  795. Activation of primary porcine endothelial cells induces release of porcine endogenous retroviruses.
    Authors: Cunningham DA, Dos Santos Cruz GJ, Fernandez-Suarez XM, Whittam AJ, Herring C, Copeman L, Richards A, Langford GA
    Transplantation, 2004-04-15;77(7):1071-9.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  796. CD14 is an acute-phase protein.
    Authors: Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C
    J. Immunol., 2004-04-01;172(7):4470-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  797. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004-03-25;104(2):314-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  798. TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
    Authors: Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J
    J. Neuroimmunol., 2004-03-01;148(1):127-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  799. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties.
    Authors: Satchell SC, Anderson KL, Mathieson PW
    J. Am. Soc. Nephrol., 2004-03-01;15(3):566-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  800. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
    Authors: Copeland S, Siddiqui J, Remick D
    J. Immunol. Methods, 2004-01-01;284(1):99-106.
    Applications: ELISA (Standard)
  801. The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells.
    Authors: Sade H, Krishna S, Sarin A
    J. Biol. Chem., 2003-10-28;279(4):2937-44.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  802. CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin.
    Authors: Cardones AR, Murakami T, Hwang ST
    Cancer Res., 2003-10-15;63(20):6751-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  803. High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis.
    Authors: Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N
    Blood, 2003-09-25;103(3):1089-98.
    Species: Human
    Sample Types: Serum
    Applications: SDS-Page
  804. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
    Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
    J. Clin. Invest., 2003-08-01;112(4):598-607.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  805. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis.
    Authors: Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T
    Proc. Natl. Acad. Sci. U.S.A., 2003-07-23;100(16):9452-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  806. Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta.
    Authors: Park JS, 107290, Kim YS, Jee YK, Myong NH, Lee KY
    Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models, 2003-05-01;57(5):463-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  807. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.
    Authors: Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D, Marme F, Cherel Y, Salvetti A, Hurtrel B, Heard JM, Riviere Y, Moullier P
    J. Virol., 2002-11-01;76(22):11605-11.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  808. LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis.
    Authors: Hikichi Y, Tsuji I, Shintani Y
    J. Biol. Chem., 2002-10-18;277(51):50054-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  809. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.
    Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M
    J. Immunol., 2002-10-15;169(8):4172-82.
    Species: Human, Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  810. Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons.
    Authors: Zhang JM, Li H, Liu B, Brull SJ
    J. Neurophysiol., 2002-09-01;88(3):1387-92.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  811. Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications.
    Authors: Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG, Anderson KC
    Oncogene, 2002-08-22;21(37):5673-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  812. The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
    Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
    Hum. Reprod., 2002-04-01;17(4):1039-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  813. IL-1, IL-6 and TNF-alpha concentrations in the peritoneal fluid of women with pelvic adhesions.
    Authors: Cheong YC, Shelton JB, Laird SM, Richmond M, Kudesia G, Li TC, Ledger WL
    Hum. Reprod., 2002-01-01;17(1):69-75.
    Species: Human
    Sample Types: Buffer
    Applications: Bioassay
  814. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases.
    Authors: Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G
    J. Leukoc. Biol., 2001-10-01;70(4):617-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  815. Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation.
    Authors: Dorge H, Neumann T, Behrends M, Skyschally A, Schulz R, Kasper C, Erbel R, Heusch G
    Am. J. Physiol. Heart Circ. Physiol., 2000-12-01;279(6):H2587-92.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  816. Tumour necrosis factor-alpha- and interleukin-1beta-stimulated cell proliferation through activation of mitogen-activated protein kinase in canine tracheal smooth muscle cells.
    Authors: Yang CM, Luo SF, Wang CC, Chiu CT, Chien CS, Lin CC, Hsiao LD
    Br. J. Pharmacol., 2000-06-01;130(4):891-9.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  817. Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
    Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
    Blood, 1996-09-15;88(6):2013-25.
    Species: Human
    Sample Types:
    Applications: Bioassay

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Reviews for Recombinant Human TNF-alpha Protein

Average Rating: 4.8 (Based on 35 Reviews)

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Recombinant Human TNF-alpha Protein
By Lana Jagannathan on 11/01/2023
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: We use this product to activate immature dendritic cells and have consistently seen activation and maturation.
Stem/Immune cell maintenance or differentiation Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Andres Ocampo Carrillo on 02/24/2023
Application: In vivo study
Reason for Rating: TNF-a dilution and using was very easy, results were very replicable and induce a very strong pro-inflammatory response.

Human TNF-a was used to induce pro-inflammatory responses in an in vivo model of arthritis using male C57BL/6J mice. rhTNF-a was able to increase accumulation of immune cells in the pannus area, and increased bone loss in the model

In vivo study Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Martin Torres on 10/01/2021
Application: In vitro bioactivity in cell culture
Reason for Rating: The protein provided reliable results in stimulating inflammation in PBMC cells treated with the protein. We obtained high IL-6 levels as a response to the TNF-a treatment (in a time-dependent manner)
In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Anonymous on 02/09/2021
Application: Assay validation
Recombinant Human TNF-alpha Protein
By Anonymous on 01/15/2021
Application: In vitro bioactivity in cell culture
Recombinant Human TNF-alpha Protein
By Anonymous on 11/30/2020
Application: Immunoassay Standard
Recombinant Human TNF-alpha Protein
By Anonymous on 11/20/2020
Application: Enzymatic activity in vitro
Reason for Rating: Worked great
Recombinant Human TNF-alpha Protein
By raghavendra vadla on 07/03/2020
Application: SDS-PAGE Control
Reason for Rating: Analysed the expression levels of control protein on treating with TNF-a for 1 hour and western blotting of whole cell lysates with control specific antibody. Observed an increased control protein levels in the TNF-a treated sample compared to untreated
SDS-PAGE Control Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Anonymous on 05/22/2020
Application: Slice electrophysiology
Reason for Rating: Works as expected.

300 micron thick slices were preincubated in TNF-alpha (100 ng/ml) for 1 h before whole-cell recordings were performed from female mice. TNF alpha reduced excitability of neurons compared to control.

Other Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Anonymous on 05/01/2020
Application: CellProlif
Reason for Rating: We always get great maturation of our dendritic cells using R&amp;Ds TNF-alpha cytokine
Cell Proliferation Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Youwen Zhang on 04/17/2020
Application: Enzymatic activity in vitro
Recombinant Human TNF-alpha Protein
By Anonymous on 01/14/2020
Application: In vitro bioactivity in cell culture
Recombinant Human TNF-alpha Protein
By Anonymous on 01/10/2020
Application: CellProlif
Recombinant Human TNF-alpha Protein
By Anonymous on 05/15/2019
Application: Cytotoxicity Assay
Reason for Rating: Nice standard curve generated for cytotoxicity analysis on L929 cells.
Other Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Anonymous on 04/30/2019
Application: Stem/Immune cell maintenance or differentiation
Recombinant Human TNF-alpha Protein
By Anonymous on 09/10/2018
Application: In vitro bioactivity in cell culture
Reason for Rating: Was used to stimulate human aortic endothelial cells.
Recombinant Human TNF-alpha Protein
By Anonymous on 08/06/2018
Application: Immunoassay Standard
Recombinant Human TNF-alpha Protein
By Balaji Mahender on 01/29/2018
Application: Immunoassay Standard
Recombinant Human TNF-alpha Protein
By Anonymous on 01/08/2018
Application: CellProlif
Reason for Rating: Works very well to induce NF-KB. Used it in our publications

We tried it for induction of NF-KB detected with luciferase and immunoblot

Cell Proliferation Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Anonymous on 10/30/2017
Application: In vivo study
Recombinant Human TNF-alpha Protein
By Billie Caison on 07/17/2017
Application: In vitro bioactivity in cell culture
In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Boubacar Barry on 06/01/2017
Application: In vitro bioactivity in cell culture
Recombinant Human TNF-alpha Protein
By Anonymous on 05/23/2017
Application: Cell migration/motility
Recombinant Human TNF-alpha Protein
By Anonymous on 05/16/2017
Application: In vitro bioactivity in cell culture
Reason for Rating: Consistent and expect bioactive in our cell culture assays

We used TNF-a to stimulation macrophages and myofibroblast

Recombinant Human TNF-alpha Protein
By Sitara Sankar on 05/15/2017
Recombinant Human TNF-alpha Protein
By Anonymous on 12/19/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: Functioned well and reproducible data with TNF from another company.
Recombinant Human TNF-alpha Protein
By Veronica Fregoso on 08/01/2016
Application: In vitro bioactivity in cell culture

Rat primary embryonic cortical culture stimulated with TNFa (10, 50, 100 ng/ml), PBS+BSA (negative stimulation control), or Okadaic Acid (OA; positive phosphorylation control) for 30 minutes. Protein isolated for western blot analysis of phospho-Akt.

In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Anonymous on 07/29/2016
Application: In vitro bioactivity in cell culture

Cultured endothelial cells were pre-treated (or not) with 1mg/mL HDL, then treated for 6 hours with 10ng/mL TNFa. TNFa treatment caused a massive upregulation of ICAM1 and E-Selectin versus control cells (untreated); HDL pre-treatment partially reversed this response.

In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Anonymous on 07/21/2016
Application: In vitro bioactivity in cell culture
Recombinant Human TNF-alpha Protein
By Anonymous on 07/21/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: At equal concentrations this protein supplied by R and D systems showed biological activity in our assay system (induction of known downstream genes) when the same protein from two other suppliers failed in all but the positive control condition.
Recombinant Human TNF-alpha Protein
By deborah webb on 05/16/2016
Application: Immunoassay Standard
Recombinant Human TNF-alpha Protein
By jinyan yu on 05/12/2016
Application: SDS-PAGE Control
SDS-PAGE Control Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By WENJIE ZHOU on 02/12/2016
Application: Cell Adhesion
Reason for Rating: This has worked well in WB
Cell Adhesion Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Yang Luo on 01/29/2016
Application: Cell Adhesion
Reason for Rating: the band is strong and clear.
Cell Adhesion Recombinant Human TNF-alpha Protein 210-TA
Recombinant Human TNF-alpha Protein
By Mengshi Ma on 01/13/2016
Application: Stimulation of human epithelial cells
Reason for Rating: stable cheap and convenience