Recombinant Mouse TNF-alpha (aa 80-235) Protein

MicroRNA-18a regulates the Pyroptosis, Apoptosis, and Necroptosis (PANoptosis) of osteoblasts induced by tumor necrosis factor-? via hypoxia-inducible factor-1?
Authors: Zhang, W;Xia, CL;Qu, YD;Li, JX;Liu, JB;Ou, SJ;Yang, Y;Qi, Y;Xu, CP;
International immunopharmacology
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors
Authors: Nakajima, S;Demers, G;Machuca-Parra, AI;Pour, ZD;Bairamian, D;Bouyakdan, K;Fisette, A;Kabahizi, A;Robb, J;Rodaros, D;Laurent, C;Ferreira, G;Arbour, N;Alquier, T;Fulton, S;
Journal of neuroinflammation
Species: Mouse
Sample Types: Whole Cells, In Vivo
Applications: Bioassay, In vivo assay

P-selectin-dependent leukocyte adhesion is governed by endolysosomal two-pore channel 2
Authors: Goretzko, J;Pauels, I;Heitzig, N;Thomas, K;Kardell, M;Na beta, J;Krogsaeter, EK;Schloer, S;Spix, B;Linard Matos, AL;Leser, C;Wegner, T;Glorius, F;Bracher, F;Gerke, V;Rossaint, J;Grimm, C;Rescher, U;
Cell reports
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
Authors: Adrian, M;Weber, M;Tsai, MC;Glock, C;Kahn, OI;Phu, L;Cheung, TK;Meilandt, WJ;Rose, CM;Hoogenraad, CC;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition
Authors: Shearn, CT;Anderson, AL;Devereaux, MW;El Kasmi, KC;Orlicky, DJ;Sokol, RJ;
PloS one
Species: Mouse
Sample Types: In Vivo
Applications: In vivo assay

Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming
Authors: Palmieri, EM;Holewinski, R;McGinity, CL;Pierri, CL;Maio, N;Weiss, JM;Tragni, V;Miranda, KM;Rouault, TA;Andresson, T;Wink, DA;McVicar, DW;
Nature communications
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
Authors: Wang, Y;Wu, T;Tsai, MC;Rezzonico, MG;Abdel-Haleem, AM;Xie, L;Gandham, VD;Ngu, H;Stark, K;Glock, C;Xu, D;Foreman, O;Friedman, BA;Sheng, M;Hanson, JE;
eLife
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Embryo-derive TNF promotes decidualization via fibroblast activation
Authors: Chen, ST;Shi, WW;Lin, YQ;Yang, ZS;Wang, Y;Li, MY;Li, Y;Liu, AX;Hu, Y;Yang, ZM;
eLife
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety
Authors: Scholz, O;Hu beta, E;Otter, S;Herebian, D;Hamacher, A;Levy, LM;Hristeva, S;Sanz, M;Ajani, H;Puentes, AR;Hoffmann, T;Hogeback, J;Unger, A;Terheyden, S;Reina do Fundo, M;Dewidar, B;Roden, M;Lammert, E;
Molecular metabolism
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Polysialylation controls immune function of myeloid cells in murine model of pneumococcal pneumonia
Authors: Shinde, P;Kiepas, A;Zhang, L;Sudhir, S;Konstantopoulos, K;Stamatos, NM;
Cell reports
Species: Mouse
Sample Types: In Vivo
Applications: In vivo assay

Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome
Authors: Zhai, R;Lenga Ma Bonda, W;Leclaire, C;Saint-Béat, C;Theilliere, C;Belville, C;Coupet, R;Blondonnet, R;Bouvier, D;Blanchon, L;Sapin, V;Jabaudon, M;
Journal of translational medicine
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inflammatory mediators act at renal pericytes to elicit contraction of vasa recta and reduce pericyte density along the kidney medullary vascular network
Authors: Lilley, RJ;Taylor, KD;Wildman, SSP;Peppiatt-Wildman, CM;
Frontiers in physiology
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Tumour extracellular vesicles and particles induce liver metabolic dysfunction
Authors: Wang, G;Li, J;Bojmar, L;Chen, H;Li, Z;Tobias, GC;Hu, M;Homan, EA;Lucotti, S;Zhao, F;Posada, V;Oxley, PR;Cioffi, M;Kim, HS;Wang, H;Lauritzen, P;Boudreau, N;Shi, Z;Burd, CE;Zippin, JH;Lo, JC;Pitt, GS;Hernandez, J;Zambirinis, CP;Hollingsworth, MA;Grandgenett, PM;Jain, M;Batra, SK;DiMaio, DJ;Grem, JL;Klute, KA;Trippett, TM;Egeblad, M;Paul, D;Bromberg, J;Kelsen, D;Rajasekhar, VK;Healey, JH;Matei, IR;Jarnagin, WR;Schwartz, RE;Zhang, H;Lyden, D;
Nature
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mechanoregulation of Osteoclastogenesis-Inducing Potentials of Fibrosarcoma Cell Line by Substrate Stiffness
Authors: Tiskratok, W;Yamada, M;Watanabe, J;Pengyu, Q;Kimura, T;Egusa, H;
International journal of molecular sciences
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

17 ?-estradiol impedes aortic root dilation and rupture in male Marfan mice
Authors: Saddic, L;Escopete, S;Zilberberg, L;Kalsow, S;Gupta, D;Egbhali, M;Parker, S;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche
Authors: Haensel, D;Daniel, B;Gaddam, S;Pan, C;Fabo, T;Bjelajac, J;Jussila, AR;Gonzalez, F;Li, NY;Chen, Y;Hou, J;Patel, T;Aasi, S;Satpathy, AT;Oro, AE;
Nature communications
Species: Mouse
Sample Types: Organoid
Applications: Cell Culture

Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis
Authors: Wayne, CR;Bremner, L;Faust, TE;Dur�n-Laforet, V;Ampatey, N;Ho, SJ;Feinberg, PA;Arvanitis, P;Ciric, B;Ruan, C;Elyaman, W;Delaney, SL;Vargas, WS;Swedo, S;Menon, V;Schafer, DP;Cutforth, T;Agalliu, D;
bioRxiv : the preprint server for biology
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

EDA2R-NIK signalling promotes muscle atrophy linked to cancer cachexia
Authors: Bilgic, SN;Domaniku, A;Toledo, B;Agca, S;Weber, BZC;Arabaci, DH;Ozornek, Z;Lause, P;Thissen, JP;Loumaye, A;Kir, S;
Nature
Species: Mouse
Sample Types: Transduced Whole Cells, Whole Cells
Applications: Bioassay

Cbfbeta Is a Novel Modulator against Osteoarthritis by Maintaining Articular Cartilage Homeostasis through TGF-beta Signaling
Authors: X Che, X Jin, NR Park, HJ Kim, HS Kyung, HJ Kim, JB Lian, JL Stein, GS Stein, JY Choi
Cells, 2023-03-31;12(7):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mycophenolic acid directly protects podocytes by preserving the actin cytoskeleton and increasing cell survival
Authors: SED Abo Zed, A Hackl, K Bohl, L Ebert, E Kieckhöfer, C Müller, K Becker, G Fink, KD Nüsken, E Nüsken, RU Müller, B Schermer, LT Weber
Scientific Reports, 2023-03-15;13(1):4281.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

BNIP3L/NIX-mediated mitophagy alleviates passive stress-coping behaviors induced by tumor necrosis factor-alpha
Authors: JJ Lu, PF Wu, JG He, YK Li, LH Long, XP Yao, JH Yang, HS Chen, XN Zhang, ZL Hu, Z Chen, F Wang, JG Chen
Molecular Psychiatry, 2023-03-13;0(0):.
Species: Mouse, Transgenic Mouse
Sample Types: In Vivo, Transfected Whole Cells
Applications: Bioassay, In vivo assay

BAFF induces CXCR5 expression during B cell differentiation in bone marrow
Authors: H Koizumi, W Fujii, C Sanjoba, Y Goto
Biochemistry and Biophysics Reports, 2023-03-07;34(0):101451.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Disruption to tRNA modification by queuine contributes to inflammatory bowel disease
Authors: J Zhang, Y Zhang, CJ McGrenagha, VP Kelly, Y Xia, J Sun
Cellular and Molecular Gastroenterology and Hepatology, 2023-02-18;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge
Authors: CM Schafer, S Martin-Alm, K Kurylowicz, N Dufton, L Osuna-Alma, ML Wu, CF Johnson, AV Shah, DO Haskard, A Buxton, E Willis, K Wheeler, S Turner, M Chlebicz, RP Scott, S Kovats, A Cleuren, GM Birdsey, AM Randi, CT Griffin
bioRxiv : the preprint server for biology, 2023-02-11;0(0):.
Species: Human, Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay

RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1alpha
Authors: PA Dumesic, SE Wilensky, S Bose, JG Van Vranke, SP Gygi, BM Spiegelman
bioRxiv : the preprint server for biology, 2023-01-07;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Identification of astrocyte regulators by nucleic acid cytometry
Authors: IC Clark, MA Wheeler, HG Lee, Z Li, LM Sanmarco, S Thaploo, CM Polonio, SW Shin, G Scalisi, AR Henry, JM Rone, F Giovannoni, M Charabati, CF Akl, DM Aleman, SEJ Zandee, A Prat, DC Douek, EA Boritz, FJ Quintana, AR Abate
Nature, 2023-01-04;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-38 suppresses abdominal aortic aneurysm formation in mice by regulating macrophages in an IL1RL2-p38 pathway-dependent manner
Authors: S Kurose, Y Matsubara, S Yoshino, K Yoshiya, K Morisaki, T Furuyama, T Hoshino, T Yoshizumi
Physiological Reports, 2023-01-01;11(2):e15581.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Improved beta-cell function leads to improved glucose tolerance in a transgenic mouse expressing lipoprotein lipase in adipocytes
Authors: H Memetimin, B Zhu, S Lee, WS Katz, PA Kern, BS Finlin
Scientific Reports, 2022-12-24;12(1):22291.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance
Authors: S Zia, BP Hammond, M Zirngibl, A Sizov, CS Baaklini, SP Panda, MFS Ho, KV Lee, A Mainali, MK Burr, S Williams, AV Caprariell, C Power, T Simmen, BJ Kerr, JR Plemel
Molecular Neurodegeneration, 2022-12-13;17(1):82.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

RAGE activation in macrophages and development of experimental diabetic polyneuropathy
Authors: S Osonoi, H Mizukami, Y Takeuchi, H Sugawa, S Ogasawara, S Takaku, T Sasaki, K Kudoh, K Ito, K Sango, R Nagai, Y Yamamoto, M Daimon, H Yamamoto, S Yagihashi
JCI Insight, 2022-12-08;7(23):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Double knockin mice show NF-kappaB trajectories in immune signaling and aging
Authors: SMT Rahman, M Aqdas, EW Martin, F Tomassoni, P Songkiatis, KS Oh, S Uderhardt, S Yun, QC Claybourne, RA McDevitt, V Greco, RN Germain, L Tessarollo, MH Sung
Cell Reports, 2022-11-22;41(8):111682.
Species: Transgenic Mouse
Sample Types: Whole Cells
Applications: Bioassay

Zinc Transporter 8 Haploinsufficiency Protects Against Beta Cell Dysfunction in Type 1 Diabetes by Increasing Mitochondrial Respiration
Authors: YK Kim, JA Walters, ND Moss, KL Wells, R Sheridan, JG Miranda, RKP Benninger, LL Pyle, RM O'Brien, L Sussel, HW Davidson
Molecular Metabolism, 2022-11-05;66(0):101632.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis
Authors: J Tong, XT Lan, Z Zhang, Y Liu, DY Sun, XJ Wang, SX Ou-Yang, CL Zhuang, FM Shen, P Wang, DJ Li
Acta pharmacologica Sinica, 2022-11-02;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Desmoglein-2 is important for islet function and beta-cell survival
Authors: KK Myo Min, D Rojas-Cana, D Penko, M DeNichilo, MP Cockshell, CB Ffrench, EJ Thompson, O Asplund, CJ Drogemulle, RB Prasad, L Groop, ST Grey, HE Thomas, T Loudovaris, TW Kay, MG Mahoney, CF Jessup, PT Coates, CS Bonder
Cell Death & Disease, 2022-10-29;13(10):911.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
Authors: A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandr, S Bhattachar, S Affo, N Fujiwara, H Su, Q Sun, TM Savage, JR Wilson-Kan, JM Caviglia, L Chin, D Chen, X Wang, S Caruso, JK Kang, AD Amin, S Wallace, R Dobie, D Yin, OM Rodriguez-, C Yin, A Mehal, B Izar, RA Friedman, RG Wells, UB Pajvani, Y Hoshida, HE Remotti, N Arpaia, J Zucman-Ros, M Karin, NC Henderson, I Tabas, RF Schwabe
Nature, 2022-10-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms
Authors: T Huu Hoang, M Sato-Matsu, H Yuasa, T Matsubara, LTT Thuy, H Ikenaga, DM Phuong, NV Hanh, VN Hieu, DV Hoang, H Hai, Y Okina, M Enomoto, A Tamori, A Daikoku, H Urushima, K Ikeda, NQ Dat, Y Yasui, H Shinkawa, S Kubo, R Yamagishi, N Ohtani, K Yoshizato, J Gracia-San, N Kawada
Science Advances, 2022-09-28;8(39):eabo5525.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria
Authors: SM Bader, SP Preston, K Saliba, A Lipszyc, ZL Grant, L Mackiewicz, A Baldi, A Hempel, MP Clark, T Peiris, W Clow, J Bjelic, MD Stutz, P Arandjelov, J Teale, F Du, L Coultas, JM Murphy, CC Allison, M Pellegrini, AL Samson
Oncogene, 2022-07-23;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Semaphorin 3A regulates alveolar bone remodeling on orthodontic tooth movement
Authors: H Kamei, T Ishii, Y Nishii
Oncogene, 2022-06-02;12(1):9243.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Humanized beta2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation
Authors: T Bromberger, S Klapproth, M Sperandio, M Moser
Cells, 2022-05-03;11(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The myokine Fibcd1 is an endogenous determinant of myofiber size and mitigates cancer-induced myofiber atrophy
Authors: FA Graca, M Rai, LC Hunt, A Stephan, YD Wang, B Gordon, R Wang, G Quarato, B Xu, Y Fan, M Labelle, F Demontis
Nature Communications, 2022-05-02;13(1):2370.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis
Authors: H Fujita, T Fujita, H Fujii
Cells, 2022-04-25;11(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
Authors: W Piao, L Li, V Saxena, J Iyyathurai, R Lakhan, Y Zhang, IT Lape, C Paluskievi, KL Hippen, Y Lee, E Silverman, MW Shirkey, LV Riella, BR Blazar, JS Bromberg
Nature Communications, 2022-04-21;13(1):2176.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
Authors: B Czaya, K Heitman, I Campos, C Yanucil, D Kentrup, D Westbrook, O Gutierrez, JL Babitt, G Jung, IB Salusky, M Hanudel, C Faul
Elife, 2022-03-18;11(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Ferroptosis as a Novel Determinant of beta-Cell Death in Diabetic Conditions
Authors: A Stancic, T Saksida, M Markelic, M Vucetic, I Grigorov, V Martinovic, D Gajic, A Ivanovic, K Velickovic, N Savic, V Otasevic
Oxidative Medicine and Cellular Longevity, 2022-03-14;2022(0):3873420.
Species: Rat
Sample Types: Whole Cells
Applications: Cell Culture

Paeoniflorin Ameliorates Skeletal Muscle Atrophy in Chronic Kidney Disease via AMPK/SIRT1/PGC-1alpha-Mediated Oxidative Stress and Mitochondrial Dysfunction
Authors: Q Li, J Wu, J Huang, R Hu, H You, L Liu, D Wang, L Wei
Frontiers in Pharmacology, 2022-03-08;13(0):859723.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

ADAM8 signaling drives neutrophil migration and ARDS severity
Authors: C Conrad, D Yildiz, SJ Cleary, A Margraf, L Cook, U Schlomann, B Panaretou, JL Bowser, H Karmouty-Q, J Li, NK Berg, SC Martin, A Aljohmani, SF Moussavi-H, KM Wang, JJ Tian, M Magnen, C Valet, L Qiu, JP Singer, HK Eltzschig, CAPSys Stu, W Bertrams, S Herold, N Suttorp, B Schmeck, ZT Ball, A Zarbock, MR Looney, JW Bartsch
JCI Insight, 2022-02-08;7(3):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Spinal microglia-derived TNF promotes the astrocytic JNK/CXCL1 pathway activation in a mouse model of burn pain
Authors: R Zhang, B Xu, N Zhang, J Niu, M Zhang, Q Zhang, D Chen, Y Shi, D Chen, K Liu, X Zhang, N Li, Q Fang
Brain, Behavior, and Immunity, 2022-02-07;102(0):23-39.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interferon-gamma Preferentially Promotes Necroptosis of Lung Epithelial Cells by Upregulating MLKL
Authors: Q Hao, S Shetty, TA Tucker, S Idell, H Tang
Cells, 2022-02-06;11(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TREM-1 is required for enhanced OpZ-induced superoxide generation following priming
Authors: S Murthy, S Baruah, JL Bowen, K Keck, BA Wagner, GR Buettner, DB Sykes, J Klesney-Ta
Journal of leukocyte biology, 2022-01-24;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Comparative Phosphoproteomics of Neuro-2a Cells under Insulin Resistance Reveals New Molecular Signatures of Alzheimer's Disease
Authors: D Kim, YS Jo, HS Jo, S Bae, YW Kwon, YS Oh, JH Yoon
International Journal of Molecular Sciences, 2022-01-17;23(2):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Behavioural immune landscapes of inflammation
Authors: G Crainiciuc, M Palomino-S, M Molina-Mor, J Sicilia, DG Aragones, JLY Li, R Madurga, JM Adrover, A Aroca-Crev, S Martin-Sal, AS Del Valle, SD Castillo, HCE Welch, O Soehnlein, M Graupera, F Sánchez-Ca, A Zarbock, TE Smithgall, M Di Pilato, TR Mempel, PL Tharaux, SF González, A Ayuso-Saci, LG Ng, GF Calvo, I González-D, F Díaz-de-Ma, A Hidalgo
Nature, 2022-01-05;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-kappaB
Authors: M Won, KA Park, S Kim, E Ju, Y Ko, H Yoo, H Ro, J Lee, J Oh, EG Lee, SY Kim, SW Nam, HM Shen, MK Yeo, JM Kim, GM Hur
Cell Death and Differentiation, 2021-11-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
Cell Reports, 2021-11-23;37(8):110037.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Dose and Dose Rate-Dependent Effects of Low-Dose Irradiation on Inflammatory Parameters in ApoE-Deficient and Wild Type Mice
Authors: A Glasow, I Patties, ND Priest, REJ Mitchel, G Hildebrand, K Manda
Cells, 2021-11-20;10(11):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TGF-beta-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma
Authors: N Miyashita, T Enokido, M Horie, K Fukuda, H Urushiyama, C Strell, H Brunnström, P Micke, A Saito, T Nagase
Scientific Reports, 2021-11-17;11(1):22380.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gasdermin D deficiency attenuates arthritis induced by traumatic injury but not autoantibody-assembled immune complexes
Authors: T Yang, K Sun, C Wang, G Swarnkar, S Quan, D Kress, J Xiao, Y Alippe, H Zheng, RH Brophy, D Hao, A McAlinden, Y Abu-Amer, J Shen, G Mbalaviele
Arthritis Research & Therapy, 2021-11-16;23(1):286.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differential Cytokine-Induced Responses of Polarized Microglia
Authors: P Chauhan, WS Sheng, S Hu, S Prasad, JR Lokensgard
Brain sciences, 2021-11-10;11(11):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The effect of macrophage polarization on the expression of the oxytocin signalling system in enteric neurons
Authors: Y Shi, S Li, H Zhang, J Zhu, T Che, B Yan, J Li, C Liu
Journal of Neuroinflammation, 2021-11-08;18(1):261.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling
Authors: C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen
The Journal of Biological Chemistry, 2021-11-03;0(0):101380.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

In situ-formed adhesive hyaluronic acid hydrogel with prolonged amnion-derived conditioned medium release for diabetic wound repair
Authors: Y Zhang, Y Zheng, F Shu, R Zhou, B Bao, S Xiao, K Li, Q Lin, L Zhu, Z Xia
Carbohydrate polymers, 2021-10-16;276(0):118752.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan
Authors: E Håland, IN Moen, E Veidal, H Hella, K Misund, TS Slørdahl, KK Starheim
Oncotarget, 2021-10-12;12(21):2158-2168.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKbeta promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice
Authors: I Papazian, E Tsoukala, A Boutou, M Karamita, K Kambas, L Iliopoulou, R Fischer, RE Kontermann, MC Denis, G Kollias, H Lassmann, L Probert
Journal of Neuroinflammation, 2021-09-26;18(1):222.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tumor Necrosis Factor-alpha utilizes MAPK/NFkappaB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway
Authors: SM Pokharel, K Chiok, NK Shil, I Mohanty, S Bose
PLoS ONE, 2021-09-22;16(9):e0257576.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis
Authors: T Zhou, E DeRoo, H Yang, A Stranz, Q Wang, R Ginnan, HA Singer, B Liu
Cells, 2021-09-12;10(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Macrophages target Listeria monocytogenes by two discrete non-canonical autophagy pathways
Authors: A Gluschko, A Farid, M Herb, D Grumme, M Krönke, M Schramm
Autophagy, 2021-09-05;0(0):1-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PI3K/ NF-kappaB-dependent TNF-alpha and HDAC activities facilitate LPS-induced RGS10 suppression in pulmonary macrophages
Authors: F Almutairi, SL Tucker, D Sarr, B Rada
Cellular Signalling, 2021-07-31;86(0):110099.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis
Authors: X Guo, J Bai, G Ge, Z Wang, Q Wang, K Zheng, H Tao, L Zhang, H Zhang, D Wang, X Zhang, H Li, G Pan, D Geng
Journal of colloid and interface science, 2021-07-24;605(0):410-424.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

alpha-Hydroxyisocaproic Acid Decreases Protein Synthesis but Attenuates TNFalpha/IFNgamma Co-Exposure-Induced Protein Degradation and Myotube Atrophy via Suppression of iNOS and IL-6 in Murine C2C12 Myotube
Authors: K Sumi, M Sakuda, K Munakata, K Nakamura, K Ashida
Nutrients, 2021-07-13;13(7):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects
Authors: J Sadek, DT Hall, B Colalillo, A Omer, AK Tremblay, V Sanguin-Ge, W Muller, S Di Marco, ME Bianchi, IE Gallouzi
Embo Molecular Medicine, 2021-06-07;0(0):e13591.
Species: Mouse
Sample Types: Organoid
Applications: Bioassay

Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice
Authors: MB Preda, CA Neculachi, IM Fenyo, AM Vacaru, MA Publik, M Simionescu, A Burlacu
Cell Death & Disease, 2021-06-02;12(6):566.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
Authors: V Farré-Alin, A Palomino-A, P Narros-Fer, AB Lopez-Rodr, C Decouty-Pe, A Muñoz-Mont, J Zamorano-F, B Mansilla-F, J Giner-Garc, P García-Fei, M Sáez-Alegr, AJ Palpán-Flo, JM Roda-Frade, CS Carabias, JM Rosa, B Civantos-M, S Yus-Teruel, L Gandía, A Lagares, BJ Hernández-, J Egea
Biomedicines, 2021-05-25;9(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TRIM26 positively regulates the inflammatory immune response through K11-linked ubiquitination of TAB1
Authors: J Zhao, B Cai, Z Shao, L Zhang, Y Zheng, C Ma, F Yi, B Liu, C Gao
Cell Death and Differentiation, 2021-05-20;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effect of NIR Laser Therapy by MLS-MiS Source on Fibroblast Activation by Inflammatory Cytokines in Relation to Wound Healing
Authors: S Genah, F Cialdai, V Ciccone, E Sereni, L Morbidelli, M Monici
Biomedicines, 2021-03-16;9(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor necrosis factor &alpha negatively regulates the retrieval and reconsolidation of hippocampus-dependent memory
Authors: S Takahashi, H Fukushima, Z Yu, H Tomita, S Kida
Brain, Behavior, and Immunity, 2021-03-05;94(0):79-88.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation
Authors: M Jafari, AM Schumacher, N Snaidero, EM Ullrich Ga, T Neziraj, V Kocsis-Jut, D Engels, T Jürgens, I Wagner, JDF Weidinger, SS Schmidt, E Beltrán, N Hagan, L Woodworth, D Ofengeim, J Gans, F Wolf, M Kreutzfeld, R Portugues, D Merkler, T Misgeld, M Kerschenst
Nature Neuroscience, 2021-01-25;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Gut-licensed IFN&gamma+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes
Authors: LM Sanmarco, MA Wheeler, C Gutiérrez-, CM Polonio, M Linnerbaue, FA Pinho-Ribe, Z Li, F Giovannoni, KV Batterman, G Scalisi, SEJ Zandee, ES Heck, M Alsuwailm, DL Rosene, B Becher, IM Chiu, A Prat, FJ Quintana
Nature, 2021-01-06;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Bergenin protects pancreatic beta cells against cytokine-induced apoptosis in INS-1E cells
Authors: SA Rajput, MR Mirza, MI Choudhary
PLoS ONE, 2020-12-21;15(12):e0241349.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Microglia Suppress Ascl1-Induced Retinal Regeneration in Mice
Authors: L Todd, C Finkbeiner, CK Wong, MJ Hooper, TA Reh
Cell Reports, 2020-12-15;33(11):108507.
Species: Transgenic Mouse
Sample Types: In Vivo
Applications: In Vivo

Inhibition of protein glycosylation is a novel pro-angiogenic strategy that acts via activation of stress pathways
Authors: C Zhong, P Li, S Argade, L Liu, A Chilla', W Liang, H Xin, B Eliceiri, B Choudhury, N Ferrara
Nature Communications, 2020-12-10;11(1):6330.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
Authors: S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim
J Neuroinflammation, 2020-10-14;17(1):299.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages
Authors: L Boytard, T Hadi, M Silvestro, H Qu, A Kumpfbeck, R Sleiman, KH Fils, D Alebrahim, F Boccalatte, M Kugler, A Corsica, BE Gelb, G Jacobowitz, G Miller, C Bellini, J Oakes, JS Silvestre, L Zangi, B Ramkhelawo
Nat Commun, 2020-08-27;11(1):4311.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

Collagen VIalpha2 chain deficiency causes trabecular bone loss by potentially promoting osteoclast differentiation through enhanced TNFalpha signaling
Authors: HT Pham, V Kram, QA Dar, T Komori, Y Ji, P Mohassel, J Rooney, L Li, TM Kilts, C Bonnemann, S Lamande, MF Young
Sci Rep, 2020-08-13;10(1):13749.
Species: Mouse
Sample Types: Recombinant Proteins
Applications: Bioassay

Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
Authors: M Liu, M Yan, H Lv, B Wang, X Lv, H Zhang, S Xiang, J Du, T Liu, Y Tian, X Zhang, F Zhou, T Cheng, Y Zhu, H Jiang, Y Cao, D Ai
Cell Rep, 2020-08-04;32(5):107990.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Serum-borne lipids amplify TLR-activated inflammatory responses
Authors: N Sharma, AS Akhade, S Ismaeel, A Qadri
J. Leukoc. Biol., 2020-07-27;0(0):.
Species: Mouse
Sample Types: Primary Cells
Applications: Cell Culture

Isoform- and Cell Type-Specific Roles of Glycogen Synthase Kinase 3 N-Terminal Serine Phosphorylation in Liver Ischemia Reperfusion Injury
Authors: M Ni, H Zhou, J Zhang, D Jin, T Lu, RW Busuttil, JW Kupiec-Weg, X Wang, Y Zhai
J. Immunol., 2020-07-17;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Paracrine regulation and improvement of &beta-cell function by thioredoxin
Authors: EM Hanschmann, SF Petry, S Eitner, CC Maresch, N Lingwal, CH Lillig, T Linn
Redox Biol, 2020-05-16;34(0):101570.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Passenger Mutations Confound Phenotypes of SARM1-Deficient Mice
Authors: MB Uccellini, SV Bardina, MT Sánchez-Ap, KM White, YJ Hou, JK Lim, A García-Sas
Cell Rep, 2020-04-07;31(1):107498.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dissecting the Regulatory Strategies of NF-&kappaB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics
Authors: KA Ngo, K Kishimoto, J Davis-Tura, A Pimplaskar, Z Cheng, R Spreafico, EY Chen, A Tam, G Ghosh, S Mitchell, A Hoffmann
Cell Rep, 2020-02-25;30(8):2758-2775.e6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Tristetraprolin regulates necroptosis during tonic Toll-like receptor 4 (TLR4) signaling in murine macrophages
Authors: A Ariana, NA Alturki, S Hajjar, DJ Stumpo, C Tiedje, ES Alnemri, M Gaestel, PJ Blackshear, S Sad
J. Biol. Chem., 2020-02-24;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MAFG-driven astrocytes promote CNS inflammation
Authors: MA Wheeler, IC Clark, EC Tjon, Z Li, SEJ Zandee, CP Couturier, BR Watson, G Scalisi, S Alkwai, V Rothhammer, A Rotem, JA Heyman, S Thaploo, LM Sanmarco, J Ragoussis, DA Weitz, K Petrecca, JR Moffitt, B Becher, JP Antel, A Prat, FJ Quintana
Nature, 2020-02-12;0(0):.
Species: Transgenic Mouse
Sample Types: Whole Cells, In Vivo, Transfected Whole Cells
Applications: Bioassay, In vivo assay

Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
Authors: FC Simões, TJ Cahill, A Kenyon, D Gavriouchk, JM Vieira, X Sun, D Pezzolla, C Ravaud, E Masmanian, M Weinberger, S Mayes, ME Lemieux, DN Barnette, M Gunadasa-R, RM Williams, DR Greaves, LA Trinh, SE Fraser, SL Dallas, RP Choudhury, T Sauka-Spen, PR Riley
Nat Commun, 2020-01-30;11(1):600.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria
Authors: TK Darling, PN Mimche, C Bray, B Umaru, LM Brady, C Stone, CE Eboumbou M, TE Lane, LS Ayong, TJ Lamb
PLoS Pathog., 2020-01-30;16(1):e1008261.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
Authors: HQ Tran, RE Ley, AT Gewirtz, B Chassaing
Nat Commun, 2019-12-11;10(1):5650.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice
Authors: J Pennig, P Scherrer, MC Gissler, N Anto-Miche, N Hoppe, L Füner, C Härdtner, P Stachon, D Wolf, I Hilgendorf, A Mullick, C Bode, A Zirlik, IJ Goldberg, F Willecke
Sci Rep, 2019-11-29;9(1):17937.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy
Authors: L Shi, J Wang, N Ding, Y Zhang, Y Zhu, S Dong, X Wang, C Peng, C Zhou, L Zhou, X Li, H Shi, W Wu, X Long, C Wu, W Liao
Nat Commun, 2019-11-28;10(1):5421.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

O-GlcNAc transferase suppresses necroptosis and liver fibrosis
Authors: B Zhang, MD Li, R Yin, Y Liu, Y Yang, KA Mitchell-R, JH Nam, R Li, L Wang, Y Iwakiri, D Chung, ME Robert, BE Ehrlich, AM Bennett, J Yu, MH Nathanson, X Yang
JCI Insight, 2019-11-01;4(21):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
Authors: S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, R Srinivasan, X Li, K Devarajan, L Prélot, CE Ang, Y Shibuya, BA Benayoun, ALS Chang, M Wernig, J Wysocka, MT Longaker, MP Snyder, A Brunet
Nature, 2019-10-23;574(7779):553-558.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Proteomic Analysis of 3T3-L1 Adipocytes Treated with Insulin and TNF-alpha
Authors: H Chan, KP Bhide, A Vaidyam, V Hedrick, TJP Sobreira, TG Sors, RW Grant, UK Aryal
Proteomes, 2019-10-20;7(4):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Serum amyloid A-mediated inflammasome activation of microglial cells in cerebral ischemia
Authors: J Yu, H Zhu, S Taheri, W Mondy, L Bonilha, GS Magwood, D Lackland, RJ Adams, MS Kindy
J. Neurosci., 2019-10-14;0(0):.
Species: Mouse
Sample Types: Cell Culture Supernates
Applications: ELISA Standard

RIPK1 mediates TNF-induced intestinal crypt apoptosis during chronic NF-kappaB activation
Authors: J Wong, R Garcia-Car, M Zelic, SB Ho, BS Boland, SJ Yao, SA Desai, S Das, N Planell, PA Harris, J Font-Burga, K Taniguchi, J Bertin, A Salas, M Pasparakis, PJ Gough, M Kelliher, M Karin, M Guma
Cell Mol Gastroenterol Hepatol, 2019-10-10;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

The serum amyloid A3 promoter-driven luciferase reporter mice is a valuable tool to image early renal fibrosis development and shows the therapeutic effect of glucosyl-hesperidin treatment
Authors: T Kumrungsee, T Kariya, K Hashimoto, T Koyano, N Yazawa, T Hashimoto, Y Sanada, M Matsuyama, Y Sotomaru, H Sakurai, FAJ van de Loo, N Yanaka
Sci Rep, 2019-10-01;9(1):14101.
Species: Human
Sample Types: Whole Cells
Applications: Stimulation

Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice
Authors: T Ondee, J Gillen, P Visitchana, P Somparn, J Issara-Amp, C Dang Phi, W Chancharoe, D Gurusamy, A Nita-Lazar, A Leelahavan
Cells, 2019-09-11;8(9):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Phlda3 regulates beta cell survival during stress
Authors: M Bensellam, JY Chan, K Lee, MV Joglekar, AA Hardikar, T Loudovaris, HE Thomas, JC Jonas, DR Laybutt
Sci Rep, 2019-09-06;9(1):12827.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MFG-E8 mediates arterial aging by promoting the proinflammatory phenotype of vascular smooth muscle cells
Authors: HY Chiang, PH Chu, TH Lee
J. Biomed. Sci., 2019-08-30;26(1):61.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
Authors: S Darkwah, N Nago, MG Appiah, PK Myint, E Kawamoto, M Shimaoka, EJ Park
Biomedicines, 2019-07-18;7(3):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TGFbeta-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis
Authors: J Li, A Ayoub, Y Xiu, X Yin, JO Sanders, A Mesfin, L Xing, Z Yao, BF Boyce
Nat Commun, 2019-06-26;10(1):2795.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Effect of TNF-α-Induced Sclerostin on Osteocytes during Orthodontic Tooth Movement
Authors: F Ohori, H Kitaura, A Marahleh, A Kishikawa, S Ogawa, J Qi, WR Shen, T Noguchi, Y Nara, I Mizoguchi
J Immunol Res, 2019-06-24;2019(0):9716758.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models
Authors: N Zhang, DP Heruth, W Wu, LQ Zhang, MN Nsumu, K Shortt, K Li, X Jiang, B Wang, C Friesen, DY Li, SQ Ye
Cell Biosci, 2019-05-14;9(0):40.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Transcriptional suppression of CPI-17 gene expression in vascular smooth muscle cells by TNF, KLF4, and Sp1 is associated with LPS-induced vascular hypocontractility, hypotension, and mortality
Authors: G Zhao, Y Zhong, W Su, S Liu, X Song, T Hou, X Mu, MC Gong, Z Guo
Mol. Cell. Biol., 2019-05-14;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment
Authors: P Zizza, R Dinami, M Porru, C Cingolani, E Salvati, A Rizzo, C D'Angelo, E Petti, CA Amoreo, M Mottolese, I Sperduti, A Chambery, R Russo, P Ostano, G Chiorino, G Blandino, A Sacconi, J Cherfils-V, C Leonetti, E Gilson, A Biroccio
Nucleic Acids Res., 2019-04-23;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
Authors: A Arredouani, A Diane, N Khattab, I Bensmail, I Aoude, M Chikri, R Mohammad, AB Abou-Samra, M Dehbi
Sci Rep, 2019-03-18;9(1):4772.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis
Authors: M Qiu, K Huang, Y Liu, Y Yang, H Tang, X Liu, C Wang, H Chen, Y Xiong, J Zhang, J Yang
Mucosal Immunol, 2019-02-12;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1
Authors: K Paduch, A Debus, B Rai, U Schleicher, C Bogdan
J. Immunol., 2019-01-21;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
Mol Brain, 2018-12-18;11(1):75.
Species: Mouse
Sample Types: Recombinant Protein
Applications: ELISA (Standard)

NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis
Authors: AE Vendrov, A Sumida, C Canugovi, A Lozhkin, T Hayami, NR Madamanchi, MS Runge
Redox Biol, 2018-11-29;21(0):101063.
Species: Mouse
Sample Types:
Applications: Bioassay

The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting
Authors: DT Hall, T Griss, JF Ma, BJ Sanchez, J Sadek, AMK Tremblay, S Mubaid, A Omer, RJ Ford, N Bedard, A Pause, SS Wing, S Di Marco, GR Steinberg, RG Jones, IE Gallouzi
EMBO Mol Med, 2018-07-01;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E
Authors: A Aguilar-Va, N Haji, D De Gregori, E Matta-Cama, MJ Eslamizade, J Popic, V Sharma, R Cao, C Rummel, A Tanti, S Wiebe, N Nuñez, S Comai, R Nadon, G Luheshi, N Mechawar, G Turecki, JC Lacaille, G Gobbi, N Sonenberg
Nat Commun, 2018-06-25;9(1):2459.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death
Authors: I Martins, SQ Raza, L Voisin, H Dakhli, A Allouch, F Law, D Sabino, D De Jong, M Thoreau, E Mintet, D Dugué, M Piacentini, ML Gougeon, F Jaulin, P Bertrand, C Brenner, DM Ojcius, G Kroemer, N Modjtahedi, E Deutsch, JL Perfettini
Cell Death Dis, 2018-06-18;9(7):716.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1
Authors: D Rijal, A Ariana, A Wight, K Kim, NA Alturki, Z Aamir, E Ametepe, RG Korneluk, C Tiedje, MB Menon, M Gaestel, S McComb, S Sad
J. Biol. Chem., 2018-06-13;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Physiological culture conditions alter myotube morphology and responses to atrophy treatments: implications for in�vitro research on muscle wasting
Authors: E Archer-Lah, C Lan, RT Jagoe
Physiol Rep, 2018-06-01;6(12):e13726.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Authors: Z Cramer, J Sadek, GG Vazquez, S Di Marco, A Pause, J Pelletier, IE Gallouzi
Sci Rep, 2018-05-30;8(1):8414.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Chemokines cooperate with TNF to provide protective anti-viral immunity and to enhance inflammation
Authors: A Alejo, MB Ruiz-Argüe, SM Pontejo, MDM Fernández, M Saraiva, B Hernáez, A Alcamí
Nat Commun, 2018-05-03;9(1):1790.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice
Authors: M Yassin, H Kissow, B Vainer, PD Joseph, A Hay-Schmid, J Olsen, AE Pedersen
Sci Rep, 2018-05-02;8(1):6905.
Species: Mouse
Sample Types: Organoids
Applications: Bioassay

Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
Authors: R Drolia, S Tenguria, AC Durkes, JR Turner, AK Bhunia
Cell Host Microbe, 2018-04-05;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ATF3 mediates the inhibitory action of TNF-α on osteoblast differentiation through the JNK signaling pathway
Authors: BC Jeong
Biochem. Biophys. Res. Commun., 2018-04-03;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
Authors: G Meyer Zu H, D Przybylski, MA Schramm, C Wang, A Schnell, Y Lee, R Sobel, A Regev, VK Kuchroo
Immunity, 2018-03-20;48(3):556-569.e7.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis
Authors: T Kobori, S Hamasaki, A Kitaura, Y Yamazaki, T Nishinaka, A Niwa, S Nakao, H Wake, S Mori, T Yoshino, M Nishibori, H Takahashi
Front Immunol, 2018-03-06;9(0):334.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome
Authors: JE Kanter, F Kramer, S Barnhart, JM Duggan, M Shimizu-Al, V Kothari, A Chait, SD Bouman, JA Hamerman, BF Hansen, GS Olsen, KE Bornfeldt
Diabetes, 2018-02-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function
Authors: HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov
Mol Metab, 2018-02-23;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
Elife, 2018-02-22;7(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

A real-time monitoring platform of myogenesis regulators using double fluorescent labeling
Authors: E Sapoznik, G Niu, Y Zhou, PM Prim, TL Criswell, S Soker
PLoS ONE, 2018-02-14;13(2):e0192654.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

An insight into the role of magnesium in the immunomodulatory properties of mesenchymal stem cells
Authors: F da Silva L, AB da Rocha R, A Hastreiter, A Nogueira-P, E Makiyama, C Colli, RA Fock
J. Nutr. Biochem., 2018-02-13;55(0):200-208.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
Neurobiol. Dis., 2018-02-09;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Corticosterone Preexposure Increases NF-?B Translocation and Sensitizes IL-1? Responses in BV2 Microglia-Like Cells
Authors: J Liu, S Mustafa, DT Barratt, MR Hutchinson
Front Immunol, 2018-01-22;9(0):3.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis
Authors: A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo
Neurobiol. Dis., 2018-01-09;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Pharmacological Effect ofCaulophyllum robustumon Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-?B, and Proinflammatory Cytokines In Vivo and In Vitro
Authors: QH Wang, SW Lv, YY Guo, JX Duan, SY Dong, QS Wang, FM Yu, H Su, HX Kuang
Evid Based Complement Alternat Med, 2017-12-31;2017(0):8134321.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis
Authors: EM Grössinger, M Kang, L Bouchareyc, R Sarin, DR Haudenschi, LN Borodinsky, IE Adamopoulo
J. Immunol., 2017-12-15;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Possible involvement of NETosis in inflammatory processes in the eye: Evidence from a small cohort of patients
Authors: T Barliya, R Dardik, Y Nisgav, M Dachbash, D Gaton, G Kenet, R Ehrlich, D Weinberger, T Livnat
Mol. Vis., 2017-12-13;23(0):922-932.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis
Authors: H Lin, R Muramatsu, N Maedera, H Tsunematsu, M Hamaguchi, Y Koyama, M Kuroda, K Ono, M Sawada, T Yamashita
EBioMedicine, 2017-12-07;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition
Authors: P Nancy, J Siewiera, G Rizzuto, E Tagliani, I Osokine, P Manandhar, I Dolgalev, C Clementi, A Tsirigos, A Erlebacher
J. Clin. Invest., 2017-11-27;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question
Authors: M Winther, A Holdfeldt, M Sundqvist, Z Rajabkhani, M Gabl, J Bylund, C Dahlgren, H Forsman
PLoS ONE, 2017-09-21;12(9):e0185132.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
JCI Insight, 2017-09-07;2(17):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TNF? drives mitochondrial stress in POMC neurons in obesity
Authors: CX Yi, M Walter, Y Gao, S Pitra, B Legutko, S Kälin, C Layritz, C García-Các, M Bielohuby, M Bidlingmai, SC Woods, A Ghanem, KK Conzelmann, JE Stern, M Jastroch, MH Tschöp
Nat Commun, 2017-05-10;8(0):15143.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
Mol Metab, 2017-05-06;6(7):725-736.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Fibroblast reticular cells engineer a blastema extracellular network during digit tip regeneration in mice
Authors: L Marrero, J Simkin, M Sammarco, K Muneoka
Regeneration (Oxf), 2017-05-03;4(2):69-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia
Authors: M Karamita, C Barnum, W Möbius, MG Tansey, DE Szymkowski, H Lassmann, L Probert
JCI Insight, 2017-04-20;2(8):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
Nat. Immunol., 2017-04-17;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endogenous TNF? orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation
Authors: S Arokiasamy, C Zakian, J Dilliway, W Wang, S Nourshargh, MB Voisin
Sci Rep, 2017-03-13;7(0):44189.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade
Authors: D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar
J. Nutr. Biochem, 2017-03-06;44(0):11-21.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4
Authors: L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders
J. Allergy Clin. Immunol, 2017-03-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway
Authors: W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao
Cell Death Discov, 2017-02-27;3(0):16097.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Extracellular Vesicles from Bone Marrow-Derived Mesenchymal Stem Cells Improve Survival from Lethal Hepatic Failure in Mice
Authors: H Haga, IK Yan, K Takahashi, A Matsuda, T Patel
Stem Cells Transl Med, 2017-02-18;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Increased mitochondrial ROS generation mediates the loss of PVAT anticontractile effect in HFD-treated obese mice
Authors: Rafael Menezes da Costa
Br. J. Pharmacol, 2017-01-12;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia
Authors: T Tsunekawa, R Banno, A Mizoguchi, M Sugiyama, T Tominaga, T Onoue, D Hagiwara, Y Ito, S Iwama, M Goto, H Suga, Y Sugimura, H Arima
EBioMedicine, 2017-01-09;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Disruption of Lipid Raft Function Increases Expression and Secretion of Monocyte Chemoattractant Protein-1 in 3T3-L1 Adipocytes
PLoS ONE, 2016-12-28;11(12):e0169005.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice
J Immunol, 2016-08-26;0(0):.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, Neutralization

RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury
Cell Death Differ, 2016-05-13;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
Authors: P Shou, Q Chen, J Jiang, C Xu, J Zhang, C Zheng, M Jiang, T Velletri, W Cao, Y Huang, Q Yang, X Han, L Zhang, L Wei, AB Rabson, YE Chin, Y Wang, Y Shi
Oncogene, 2016-04-25;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response
Authors: Shweta Pasi
J Biol Chem, 2016-03-28;291(23):12358-69.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Replacing the Promoter of the Murine Gene Encoding P-selectin with the Human Promoter Confers Human-like Basal and Inducible Expression in Mice.
Authors: Liu Z, Zhang N, Shao B, Panicker S, Fu J, McEver R
J Biol Chem, 2015-12-02;291(3):1441-7.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms.
Authors: Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H
J Immunol, 2015-09-21;195(9):4415-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension.
Authors: Goodall L, Ovecka M, Rycroft D, Friel S, Sanderson A, Mistry P, Davies M, Stoop A
PLoS ONE, 2015-09-09;10(9):e0137065.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
Authors: Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G
J Immunol, 2015-09-09;195(8):3531-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The role of the prostaglandin E2 receptors in vulnerability of oligodendrocyte precursor cells to death.
Authors: Carlson N, Bellamkonda S, Schmidt L, Redd J, Huecksteadt T, Weber L, Davis E, Wood B, Maruyama T, Rose J
J Neuroinflammation, 2015-05-23;12(0):101.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion.
Authors: Fu X, Xiao J, Wei Y, Li S, Liu Y, Yin J, Sun K, Sun H, Wang H, Zhang Z, Zhang B, Sheng C, Wang H, Hu P
Cell Res, 2015-05-15;25(6):655-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells.
Authors: Guay C, Menoud V, Rome S, Regazzi R
Cell Commun Signal, 2015-03-19;13(0):17.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
Authors: Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E
Nat Med, 2015-03-16;21(4):363-72.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression.
Authors: Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell R, Spilianakis C
Proc Natl Acad Sci U S A, 2015-03-13;112(13):E1577-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Mitochondria and NADPH oxidases are the major sources of TNF-alpha/cycloheximide-induced oxidative stress in murine intestinal epithelial MODE-K cells.
Authors: Babu D, Leclercq G, Goossens V, Vanden Berghe T, Van Hamme E, Vandenabeele P, Lefebvre R
Cell Signal, 2015-02-26;27(6):1141-58.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination.
Authors: Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, Fung H, Albrecht S, Alexandropoulos K, McCauley D, Chook Y, Kuhlmann T, Kidd G, Shacham S, Casaccia P
Nat Neurosci, 2015-02-23;18(4):511-20.
Species: Mouse
Sample Types: Whole Organism
Applications: In Vivo

ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.
Authors: Hennigar S, Seo Y, Sharma S, Soybel D, Kelleher S
Sci Rep, 2015-01-26;5(0):8033.
Species: Mouse
Sample Types: Whole Organism
Applications: In Vivo

Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
Authors: Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, West J, Hansen K, Horan K, Jakobsen M, O'Hare P, Adler H, Sun R, Ploegh H, Damania B, Upton J, Fitzgerald K, Paludan S
J Immunol, 2015-01-16;194(4):1819-31.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

The generation of neutrophils in the bone marrow is controlled by autophagy.
Authors: Rozman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H
Cell Death Differ, 2014-10-17;22(3):445-56.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Transforming growth factor beta-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling.
Authors: Li L, Chen Y, Doan J, Murray J, Molkentin J, Liu Q
Circulation, 2014-10-02;130(24):2162-72.
Species: Mouse, Rat
Sample Types: Whole Cells
Applications: Bioassay

Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway.
Authors: Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D
Elife, 2014-09-16;3(0):e02809.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of Ca2+-independent phospholipase A2beta (iPLA2beta) ameliorates islet infiltration and incidence of diabetes in NOD mice.
Authors: Bone R, Gai Y, Magrioti V, Kokotou M, Ali T, Lei X, Tse H, Kokotos G, Ramanadham S
Diabetes, 2014-09-11;64(2):541-54.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
Authors: Kowalewska P, Patrick A, Fox-Robichaud A
PLoS ONE, 2014-09-03;9(9):e104537.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

HDAC inhibitor-mediated beta-cell protection against cytokine-induced toxicity is STAT1 Tyr701 phosphorylation independent.
Authors: Dahllof M, Christensen D, Harving M, Wagner B, Mandrup-Poulsen T, Lundh M
J Interferon Cytokine Res, 2014-07-25;35(1):63-70.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.
Authors: McComb S, Cessford E, Alturki N, Joseph J, Shutinoski B, Startek J, Gamero A, Mossman K, Sad S
Proc Natl Acad Sci U S A, 2014-07-21;111(31):E3206-13.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Free fatty acids and IL-6 induce adipocyte galectin-3 which is increased in white and brown adipose tissues of obese mice.
Authors: Krautbauer S, Eisinger K, Hader Y, Buechler C
Cytokine, 2014-07-17;69(2):263-71.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
Nat Commun, 2014-07-14;5(0):4436.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

beta-Arrestin 2 negatively regulates Toll-like receptor 4 (TLR4)-triggered inflammatory signaling via targeting p38 MAPK and interleukin 10.
Authors: Li H, Hu D, Fan H, Zhang Y, LeSage G, Caudle Y, Stuart C, Liu Z, Yin D
J Biol Chem, 2014-07-10;289(33):23075-85.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
PLoS ONE, 2014-07-10;9(7):e101937.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2alpha.
Authors: Grabiner M, Fu Z, Wu T, Barry K, Schwarzer C, Machen T
J Immunol, 2014-07-02;193(3):1459-67.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Authors: Dang, Shipeng, Xu, Huanbai, Xu, Congfeng, Cai, Wei, Li, Qian, Cheng, Yiji, Jin, Min, Wang, Ru-Xing, Peng, Yongde, Zhang, Yi, Wu, Changpin, He, Xiaozhou, Wan, Bing, Zhang, Yanyun
Autophagy, 2014-05-14;10(7):1301-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts.
Authors: Le Goff B, Singbrant S, Tonkin B, Martin T, Romas E, Sims N, Walsh N
Cytokine, 2014-04-22;68(2):101-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-alpha and interleukin-1beta but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gingipain.
Authors: Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, Hoshino M, Imamura T, Akiyama C, Yasuhara R, Mishima K, Maruyama T, Kohda C, Tanaka K, Potempa J, Yasuda H, Baba K, Kamijo R
J Biol Chem, 2014-04-22;289(22):15621-30.
Species: Bacteria - Porphyromonas gingivalis, Mouse
Sample Types: Protein, Whole Cells
Applications: Bioassay, Degradation

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
Nature, 2014-04-13;509(7499):235-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Matrix metalloproteinase-9 deficiency attenuates diabetic nephropathy by modulation of podocyte functions and dedifferentiation.
Authors: Li S, Huang P, Yang A, Tarng D, Yang W, Lin C, Chen J, Schmid-Schonbein G, Lin S
Kidney Int, 2014-03-26;86(2):358-69.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Polymicrobial sepsis alters antigen-dependent and -independent memory CD8 T cell functions.
Authors: Duong S, Condotta S, Rai D, Martin M, Griffith T, Badovinac V
J Immunol, 2014-03-19;192(8):3618-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Toxoplasma gondii virulence factor ROP18 inhibits the host NF-kappaB pathway by promoting p65 degradation.
Authors: Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J
J Biol Chem, 2014-03-19;289(18):12578-92.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IFN-gamma or IFN-alpha ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex.
Authors: Tamiya H, Terao M, Takiuchi T, Nakahara M, Sasaki Y, Katayama I, Yoshikawa H, Iwai K
J Immunol, 2014-03-14;192(8):3793-804.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
Nat Med, 2014-03-02;20(4):377-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Is SIRT2 required for necroptosis?
Authors: Newton K, Hildebrand J, Shen Z, Rodriguez D, Alvarez-Diaz S, Petersen S, Shah S, Dugger D, Huang C, Auwerx J, Vandenabeele P, Green D, Ashkenazi A, Dixit V, Kaiser W, Strasser A, Degterev A, Silke J
Nature, 2014-02-27;506(7489):E4-6.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
BMC Cancer, 2014-02-20;14(0):113.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-alpha secretion.
Authors: Berta T, Park C, Xu Z, Xie R, Liu T, Lu N, Liu Y, Ji R
J Clin Invest, 2014-02-17;124(3):1173-86.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lack of host gut microbiota alters immune responses and intestinal granuloma formation during schistosomiasis.
Authors: Holzscheiter M, Layland L, Loffredo-Verde E, Mair K, Vogelmann R, Langer R, Wagner H, Prazeres da Costa C
Clin Exp Immunol, 2014-02-01;175(2):246-57.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endothelial cell-derived chemerin promotes dendritic cell transmigration.
Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
J Immunol, 2014-01-27;192(5):2366-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.
Authors: McMichael B, Scherer K, Franklin N, Lee B
PLoS ONE, 2014-01-23;9(1):e87402.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via beta2 integrins (CD11/CD18).
Authors: Weckbach L, Gola A, Winkelmann M, Jakob S, Groesser L, Borgolte J, Pogoda F, Pick R, Pruenster M, Muller-Hocker J, Deindl E, Sperandio M, Walzog B
Blood, 2014-01-23;123(12):1887-96.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Unbiased expression mapping identifies a link between the complement and cholinergic systems in the rat central nervous system.
Authors: Lindblom R, Strom M, Heinig M, Al Nimer F, Aeinehband S, Berg A, Dominguez C, Vijayaraghavan S, Zhang X, Harnesk K, Zelano J, Hubner N, Cullheim S, Darreh-Shori T, Diez M, Piehl F
J Immunol, 2013-12-18;192(3):1138-53.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
PLoS ONE, 2013-12-16;8(12):e84107.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Technical advance: monitoring the trafficking of neutrophil granulocytes and monocytes during the course of tissue inflammation by noninvasive 19F MRI.
Authors: Temme S, Jacoby C, Ding Z, Bonner F, Borg N, Schrader J, Flogel U
J Leukoc Biol, 2013-12-06;95(4):689-97.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TGF-beta promotes immune responses in the presence of mesenchymal stem cells.
Authors: Xu C, Yu P, Han X, DU L, Gan J, Wang Y, Shi Y
J Immunol, 2013-11-29;192(1):103-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Optineurin insufficiency impairs IRF3 but not NF-kappaB activation in immune cells.
Authors: Munitic I, Giardino Torchia M, Meena N, Zhu G, Li C, Ashwell J
J Immunol, 2013-11-15;191(12):6231-40.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis.
Authors: Moon C, VanDussen K, Miyoshi H, Stappenbeck T
Mucosal Immunol, 2013-11-13;7(4):818-28.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-kappaB (NF-kappaB): a feed-forward loop for systemic and vascular inflammation.
Authors: Leslie K, Song G, Barrick S, Wehbi V, Vilardaga J, Bauer P, Bisello A
J Biol Chem, 2013-11-06;288(51):36426-36.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
Authors: Kook, S, Zhan, X, Cleghorn, W M, Benovic, J L, Gurevich, V V, Gurevich, E V
Cell Death Differ, 2013-10-18;21(1):172-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis.
Authors: Xu C, Chang A, Hack B, Eadon M, Alper S, Cunningham P
Kidney Int, 2013-07-31;85(1):72-81.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
Authors: Steelman A, Smith R, Welsh C, Li J
J Biol Chem, 2013-07-08;288(33):23776-87.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Enhancement of inflammatory protein expression and nuclear factor Kappab (NF-Kappab) activity by trichostatin A (TSA) in OP9 preadipocytes.
Authors: Sato T, Kotake D, Hiratsuka M, Hirasawa N
PLoS ONE, 2013-03-26;8(3):e59702.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-delta.
Authors: Do-Umehara H, Chen C, Urich D, Zhou L, Qiu J, Jang S, Zander A, Baker M, Eilers M, Sporn P, Ridge K, Sznajder J, Budinger G, Mutlu G, Lin A, Liu J
Nat Immunol, 2013-03-24;14(5):461-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells.
Authors: Yoshimura T, Howard O, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim J, Wang J
PLoS ONE, 2013-03-18;8(3):e58791.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
J Immunol, 2013-03-13;190(8):4196-204.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response.
Authors: Dearth C, Goh Q, Marino J, Cicinelli P, Torres-Palsa M, Pierre P, Worth R, Pizza F
PLoS ONE, 2013-03-11;8(3):e58486.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.
Authors: Sandig H, Jobbings C, Roldan N, Whittingham-Dowd J, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S
Eur J Immunol, 2013-03-06;43(4):979-88.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
J Biol Chem, 2013-03-04;288(18):12699-711.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuli.
Authors: Sheng Y, Triyana S, Wang R, Das I, Gerloff K, Florin T, Sutton P, McGuckin M
Mucosal Immunol, 2012-11-14;6(3):557-68.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion.
Authors: Shrestha N, Bahnan W, Wiley D, Barber G, Fields K, Schesser K
J Biol Chem, 2012-07-02;287(34):28738-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Regulation of innate CD8+ T-cell activation mediated by cytokines.
Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
Authors: Proebstl D, Voisin MB, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S
J. Exp. Med., 2012-05-21;209(6):1219-34.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Matrix metalloprotease 9 mediates neutrophil migration into the airways in response to influenza virus-induced toll-like receptor signaling.
Authors: Bradley LM, Douglass MF, Chatterjee D, Akira S, Baaten BJ
PLoS Pathog., 2012-04-05;8(4):e1002641.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice.
Authors: Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Hilliard KL, Zhang X, Sabharwal V, Algul H, Akira S, Schmid RM, Pelton SI, Spira A, Mizgerd JP
J. Clin. Invest., 2012-04-02;122(5):1758-63.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression.
Authors: Liu N, Meng Z, Lou G, Zhou W, Wang X, Zhang Y, Zhang L, Liu X, Yen Y, Lai L, Forman BM, Xu Z, Xu R, Huang W
Mol. Endocrinol., 2012-04-02;26(5):775-85.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
PLoS ONE, 2012-02-29;7(2):e32125.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
Am. J. Pathol., 2011-10-26;180(1):365-74.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

IL-22 Is Produced by Innate Lymphoid Cells and Limits Inflammation in Allergic Airway Disease.
Authors: Taube C, Tertilt C, Gyulveszi G, Dehzad N, Kreymborg K, Schneeweiss K, Michel E, Reuter S, Renauld JC, Arnold-Schild D, Schild H, Buhl R, Becher B
PLoS ONE, 2011-07-18;6(7):e21799.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
Authors: El-Behi M, Ciric B, Dai H
Nat. Immunol., 2011-04-24;12(6):568-75.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-17A and TNF-alpha Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro.
Authors: Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS
J. Immunol., 2011-01-31;186(5):3197-205.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TNFR2 interposes the proliferative and NF-kappaB-mediated inflammatory response by podocytes to TNF-alpha.
Authors: Bruggeman LA, Drawz PE, Kahoud N, Lin K, Barisoni L, Nelson PJ
Lab. Invest., 2011-01-10;91(3):413-25.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo.
Authors: Petri B, Kaur J, Long EM, Li H, Parsons SA, Butz S, Phillipson M, Vestweber D, Patel KD, Robbins SM, Kubes P
Blood, 2010-10-28;117(3):942-52.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.
Authors: Le Gall SM, Maretzky T, Issuree PD, Niu XD, Reiss K, Saftig P, Khokha R, Lundell D, Blobel CP
J. Cell. Sci., 2010-10-27;123(0):3913-22.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay, ELISA (Standard)

Tumor necrosis factor-alpha regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells.
Authors: Bhatnagar S, Panguluri SK, Gupta SK, Dahiya S, Lundy RF, Kumar A
PLoS ONE, 2010-10-12;5(10):e13262.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
Authors: Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE
J. Immunol., 2010-09-10;185(7):4354-62.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Vitamin D3 upregulated protein 1 suppresses TNF-alpha-induced NF-kappaB activation in hepatocarcinogenesis.
Authors: Kwon HJ, Won YS, Suh HW, Jeon JH, Shao Y, Yoon SR, Chung JW, Kim TD, Kim HM, Nam KH, Yoon WK, Kim DG, Kim JH, Kim YS, Kim DY, Kim HC, Choi I
J. Immunol., 2010-09-08;185(7):3980-9.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis.
Authors: Chou RC, Kim ND, Sadik CD
Immunity, 2010-08-27;33(2):266-78.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
Authors: Suzuki K, Maruya M, Kawamoto S
Immunity, 2010-07-23;33(1):71-83.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice.
Authors: Murthy A, Defamie V, Smookler DS
J. Clin. Invest., 2010-07-12;120(8):2731-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism.
Authors: Tiller G, Laumen H, Fischer-Posovszky P, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H
Int J Obes (Lond), 2010-06-15;35(2):208-16.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis.
Authors: Bixel MG, Li H, Petri B, Khandoga AG, Khandoga A, Zarbock A, Wolburg-Buchholz K, Wolburg H, Sorokin L, Zeuschner D, Maerz S, Butz S, Krombach F, Vestweber D
Blood, 2010-05-17;116(7):1172-84.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo.
Authors: Frommhold D, Kamphues A, Hepper I, Pruenster M, Lukic IK, Socher I, Zablotskaya V, Buschmann K, Lange-Sperandio B, Schymeinsky J, Ryschich E, Poeschl J, Kupatt C, Nawroth PP, Moser M, Walzog B, Bierhaus A, Sperandio M
Blood, 2010-04-20;116(5):841-9.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
J. Immunol., 2010-03-24;184(0):5263-70.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.
Authors: Mueller H, Stadtmann A, Van Aken H, Hirsch E, Wang D, Ley K, Zarbock A
Blood, 2010-02-18;115(15):3118-27.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway.
Authors: Lebrun-Julien F, Bertrand MJ, De Backer O, Stellwagen D, Morales CR, Di Polo A, Barker PA
Proc. Natl. Acad. Sci. U.S.A., 2010-02-03;107(8):3817-22.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability.
Authors: Blanchet MR, Gold M, Maltby S, Bennett J, Petri B, Kubes P, Lee DM, McNagny KM
J. Immunol., 2009-12-28;184(3):1292-9.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Epifluorescence intravital microscopy of murine corneal dendritic cells.
Authors: Lee EJ, Rosenbaum JT, Planck SR
Invest. Ophthalmol. Vis. Sci., 2009-12-10;51(4):2101-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing.
Authors: Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, Matsuo K
J. Bone Miner. Res., 2009-12-01;24(12):2056-65.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
J. Immunol., 2009-10-19;183(10):6135-44.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
Mucosal Immunol, 2009-10-07;3(1):40-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A lymphotoxin-driven pathway to hepatocellular carcinoma.
Authors: Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M
Cancer Cell, 2009-10-06;16(4):295-308.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
Nat. Med., 2009-09-20;15(10):1170-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Direct bone formation during distraction osteogenesis does not require TNFalpha receptors and elevated serum TNFalpha fails to inhibit bone formation in TNFR1 deficient mice.
Authors: Wahl EC, Aronson J, Liu L, Skinner RA, Miller MJ, Cockrell GE, Fowlkes JL, Thrailkill KM, Bunn RC, Ronis MJ, Lumpkin CK
Bone, 2009-09-17;46(2):410-7.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice.
Authors: Page K, Ledford JR, Zhou P, Wills-Karp M
J. Immunol., 2009-08-10;183(5):3400-8.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Primed CD8(+) T-cell responses to allogeneic endothelial cells are controlled by local complement activation.
Authors: Raedler H, Yang M, Lalli PN
Am. J. Transplant., 2009-06-26;9(8):1784-95.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant.
Authors: Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, Yoshikawa T, Hiroi T, Itoh N, Kawai Y, Mayumi T, Kamada H, Tsunoda S, Tsutsumi Y
Biochem. Biophys. Res. Commun., 2009-05-04;384(3):296-300.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury.
Authors: Hidalgo A, Chang J, Jang JE, Peired AJ, Chiang EY, Frenette PS
Nat. Med., 2009-03-22;15(4):384-91.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
Microbes Infect., 2009-03-13;11(4):524-30.
Applications: ELISA (Standard)

Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells.
Authors: Moser M, Bauer M, Schmid S, Ruppert R, Schmidt S, Sixt M, Wang HV, Sperandio M, Fassler R
Nat. Med., 2009-02-22;15(3):300-5.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Induction of hepatitis by JNK-mediated expression of TNF-alpha.
Authors: Das M, Sabio G, Jiang F, Rincon M, Flavell RA, Davis RJ
Cell, 2009-01-23;136(2):249-60.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
J. Exp. Med., 2009-01-12;206(1):69-78.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
Arthritis Rheum., 2008-11-01;58(11):3510-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2.
Authors: Audoy-Remus J, Richard JF, Soulet D, Zhou H, Kubes P, Vallieres L
J. Neurosci., 2008-10-08;28(41):10187-99.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis.
Authors: Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M
J. Invest. Dermatol., 2008-10-02;129(3):650-6.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation.
Authors: Shigeta A, Matsumoto M, Tedder TF, Lowe JB, Miyasaka M, Hirata T
Blood, 2008-09-25;112(13):4915-23.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.
Authors: Zarbock A, Abram CL, Hundt M, Altman A, Lowell CA, Ley K
J. Exp. Med., 2008-09-15;205(10):2339-47.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
Authors: Mahoney DJ, Cheung HH, Mrad RL, Plenchette S, Simard C, Enwere E, Arora V, Mak TW, LaCasse EC, Waring J, Korneluk RG
Proc. Natl. Acad. Sci. U.S.A., 2008-08-12;105(33):11778-83.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

XIAP regulates intracellular ROS by enhancing antioxidant gene expression.
Authors: Resch U, Schichl YM, Sattler S, de Martin R
Biochem. Biophys. Res. Commun., 2008-08-08;375(1):156-61.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc.
Authors: Yakubenia S, Frommhold D, Scholch D, Hellbusch CC, Korner C, Petri B, Jones C, Ipe U, Bixel MG, Krempien R, Sperandio M, Wild MK
Blood, 2008-06-09;112(4):1472-81.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
Authors: Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
Exp. Hematol., 2008-05-01;36(5):545-558.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism.
Authors: Norman MU, Zbytnuik L, Kubes P
Eur. J. Immunol., 2008-05-01;38(5):1368-80.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance.
Authors: Ashare A, Nymon AB, Doerschug KC, Morrison JM, Monick MM, Hunninghake GW
Am. J. Respir. Crit. Care Med., 2008-04-24;178(2):149-57.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo.
Authors: Kerfoot SM, Andonegui G, Bonder CS, Liu L
Am. J. Physiol. Heart Circ. Physiol., 2008-04-18;294(6):H2524-34.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TNF receptor independent activation of the cytomegalovirus major immediate early enhancer in response to transplantation.
Authors: Zhang Z, Kim SJ, Varghese T, Thomas G, Hummel M, Abecassis M
Transplantation, 2008-04-15;85(7):1039-45.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
Immunology, 2008-04-03;125(2):272-9.
Applications: ELISA (Standard)

A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI.
Authors: von Zur Muhlen C, Sibson NR, Peter K, Campbell SJ, Wilainam P, Grau GE, Bode C, Choudhury RP, Anthony DC
J. Clin. Invest., 2008-03-01;118(3):1198-207.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages.
Authors: Zhang J, Wu Y, Zhang Y, LeRoith D, Bernlohr DA, Chen X
Mol. Endocrinol., 2008-02-21;22(6):1416-26.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
Blood, 2007-12-21;111(8):4096-105.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
Nature, 2007-12-06;450(7171):825-31.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells.
Authors: Kaminski A, Ma N, Donndorf P, Lindenblatt N, Feldmeier G, Ong LL, Furlani D, Skrabal CA, Liebold A, Vollmar B, Steinhoff G
Lab. Invest., 2007-11-26;88(1):58-69.
Species: Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Role of interleukin-1beta and tumor necrosis factor-alpha-dependent expression of cyclooxygenase-2 mRNA in thermal hyperalgesia induced by chronic inflammation in mice.
Authors: Narita M, Shimamura M, Imai S, Kubota C, Yajima Y, Takagi T, Shiokawa M, Inoue T, Suzuki M, Suzuki T
Neuroscience, 2007-11-12;152(2):477-86.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis.
Authors: Antonopoulos C, Cumberbatch M, Mee JB, Dearman RJ, Wei XQ, Liew FY, Kimber I, Groves RW
J. Leukoc. Biol., 2007-11-05;83(2):361-7.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate.
Authors: Zetterstrom CK, Jiang W, Wahamaa H, Ostberg T, Aveberger AC, Schierbeck H, Lotze MT, Andersson U, Pisetsky DS, Erlandsson Harris H
J. Leukoc. Biol., 2007-10-03;83(1):31-8.
Applications: ELISA (Standard)

Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.
Authors: Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE
J. Immunol., 2007-08-01;179(3):1872-83.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo.
Authors: Liu L, Puri KD, Penninger JM, Kubes P
Blood, 2007-05-08;110(4):1191-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Interferon-gamma synergises with tumour necrosis factor and lymphotoxin-alpha to enhance the mRNA and protein expression of adhesion molecules in mouse brain endothelial cells.
Authors: Weiser S, Miu J, Ball HJ, Hunt NH
Cytokine, 2007-04-06;37(1):84-91.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine.
Authors: Dogra C, Changotra H, Wedhas N, Qin X, Wergedal JE, Kumar A
FASEB J., 2007-02-21;21(8):1857-69.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Dickkopf-1 is a master regulator of joint remodeling.
Authors: Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G
Nat. Med., 2007-01-21;13(2):156-63.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice.
Authors: Robertson SA, Care AS, Skinner RJ
Biol. Reprod., 2007-01-10;76(5):738-48.
Applications: ELISA (Standard)

Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
J. Immunol., 2006-12-15;177(12):8650-7.
Applications: ELISA (Standard)

Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
J. Immunol., 2006-12-01;177(11):7665-72.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
J. Immunol., 2006-12-01;177(11):7980-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
J. Exp. Med., 2006-11-20;203(12):2763-77.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice.
Authors: Penido C, Conte FP, Chagas MS, Rodrigues CA, Pereira JF, Henriques MG
Inflamm. Res., 2006-11-01;55(11):457-64.
Applications: ELISA (Standard)

Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.
Authors: Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R
Circulation, 2006-09-25;114(14):1504-11.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors.
Authors: Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, Edebro H, Forsman M, Bystrom M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK
Infect. Immun., 2006-09-18;74(12):6730-8.
Applications: ELISA (Standard)

Suppressive effect of simvastatin on interferon-beta-induced expression of CC chemokine ligand 5 in microglia.
Authors: Nakamichi K, Saiki M, Kitani H, Kuboyama Y, Morimoto K, Takayama-Ito M, Kurane I
Neurosci. Lett., 2006-09-15;407(3):205-10.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-04;291(6):L1246-55.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
Authors: Osuchowski MF, Welch K, Siddiqui J, Remick DG
J. Immunol., 2006-08-01;177(3):1967-74.
Applications: ELISA (Standard)

Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1alpha, TNF-alpha and LTB(4).
Authors: Ramos CD, Fernandes KS, Canetti C, Teixeira MM, Silva JS, Cunha FQ
Eur. J. Immunol., 2006-08-01;36(8):2025-34.
Applications: ELISA (Standard)

Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1.
Authors: Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, Schwartz M
Proc. Natl. Acad. Sci. U.S.A., 2006-07-24;103(31):11784-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Adenoviral-mediated overexpression of SOCS3 enhances IgG immune complex-induced acute lung injury.
Authors: Gao H, Hoesel LM, Guo RF, Rancilio NJ, Sarma JV, Ward PA
J. Immunol., 2006-07-01;177(1):612-20.
Applications: ELISA (Standard)

Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
J Ethnopharmacol, 2006-03-10;106(3):418-24.
Applications: ELISA (Standard)

TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
Authors: Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A
Arthritis Res. Ther., 2006-01-01;8(5):R146.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury.
Authors: Mendez MP, Morris SB, Wilcoxen S, Greeson E, Moore B, Paine R
Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L962-70.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
Mol. Cell. Neurosci., 2005-11-16;31(1):149-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
Authors: Costa SK, Yshii LM, Poston RN, Muscara MN, Brain SD
J. Neuroimmunol., 2005-11-02;171(1):99-109.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.
Authors: Niederkofler V, Salie R, Arber S
J. Clin. Invest., 2005-08-01;115(8):2180-6.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Sequential ELISA to profile multiple cytokines from small volumes.
Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
J. Immunol. Methods, 2005-07-01;302(1):172-81.
Applications: ELISA (Standard)

Antibody-bound beta-amyloid precursor protein stimulates the production of tumor necrosis factor-alpha and monocyte chemoattractant protein-1 by cortical neurons.
Authors: Gonzalez de Aguilar JL, Dupuis L, Larmet Y
Neurobiol. Dis., 2005-06-01;19(1):129-41.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system.
Authors: Ching S, He L, Lai W, Quan N
Brain Behav. Immun., 2005-03-01;19(2):127-37.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Selective macrophage suppression during sepsis.
Authors: Ellaban E, Bolgos G, Remick D
Cell. Immunol., 2005-02-26;231(1):103-11.
Applications: ELISA (Standard)

IL-1 mediates TNF-induced osteoclastogenesis.
Authors: Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL
J. Clin. Invest., 2005-02-01;115(2):282-90.
Species: Human, Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

MyD88-dependent induction of allergic Th2 responses to intranasal antigen.
Authors: Piggott DA, Eisenbarth SC, Xu L, Constant SL, Huleatt JW, Herrick CA, Bottomly K
J. Clin. Invest., 2005-02-01;115(2):459-67.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Role for tumor necrosis factor alpha in murine cytomegalovirus transcriptional reactivation in latently infected lungs.
Authors: Simon CO, Seckert CK, Dreis D, Reddehase MJ, Grzimek NK
J. Virol., 2005-01-01;79(1):326-40.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Transcriptional profiling of lipopolysaccharide-induced acute lung injury.
Authors: Jeyaseelan S, Chu HW, Young SK, Worthen GS
Infect. Immun., 2004-12-01;72(12):7247-56.
Applications: ELISA (Standard)

HIV-1 Tat increases the adhesion of monocytes and T-cells to the endothelium in vitro and in vivo: implications for AIDS-associated vasculopathy.
Authors: Matzen K, Dirkx AE, oude Egbrink MG, Speth C, Gotte M, Ascherl G, Grimm T, Griffioen AW, Sturzl M
Virus Res., 2004-09-01;104(2):145-55.
Species: Mouse
Sample Types: Interstitial Fluid
Applications: Bioassay

Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
J. Immunol., 2004-06-15;172(12):7408-16.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Thyrocytes isolated from autoimmune-diseased thyroids secrete soluble tumor necrosis factor-R1 that is related to their elevated protein kinase C activity.
Authors: LaBue M, Colburn KK, Green LM
Thyroid, 2004-04-01;14(4):249-62.
Applications: Western Blot

T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node.
Authors: Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I
Proc. Natl. Acad. Sci. U.S.A., 2004-01-13;101(4):998-1003.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation.
Authors: Dunne JL, Collins RG, Beaudet AL, Ballantyne CM, Ley K
J. Immunol., 2003-12-01;171(11):6105-11.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation.
Authors: Hong S, Gronert K, Devchand PR, Moussignac RL, Serhan CN
J. Biol. Chem., 2003-02-17;278(17):14677-87.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Elevated levels of tumor necrosis factor alpha (TNF-alpha) in human immunodeficiency virus type 1-transgenic mice: prevention of death by antibody to TNF-alpha.
Authors: De SK, Devadas K, Notkins AL
J. Virol., 2002-11-01;76(22):11710-4.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

CD40 regulates the processing of NF-kappaB2 p100 to p52.
Authors: Coope HJ, Atkinson PG, Huhse B, Belich M, Janzen J, Holman MJ, Klaus GG, Johnston LH, Ley SC
EMBO J., 2002-10-15;21(20):5375-85.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function.
Authors: Miller G, 107331, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1alpha and the NAMPT-NAD+ pathway, 2002-09-15;169(6):2875-85.
Species: Mouse
Sample Types: Cell Culture Supernates

Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy.
Authors: Chaisson ML, Brooling JT, Ladiges W, Tsai S, Fausto N
J. Clin. Invest., 2002-07-01;110(2):193-202.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Modulation of marrow proliferation and chemosensitivity by tumor-produced cytokines from syngeneic pancreatic tumor lines.
Authors: Blumenthal RD, Reising A, Leon E
Clin. Cancer Res., 2002-05-01;8(5):1301-9.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
Authors: Medvedev AE, Kopydlowski KM, Vogel SN
J. Immunol., 2000-06-01;164(11):5564-74.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay