(RS)-3,4-DCPG
Chemical Name: (RS)-3,4-Dicarboxyphenylglycine
Purity: ≥99%
Biological Activity
(RS)-3,4-DCPG is a systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG or (R)-3,4,-DCPG.S-enantiomer and R-enantiomer also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice.
Moldrich et al.
Neuropharmacology, 2001;40:732 -
Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones.
Thomas et al.
Eur.J.Pharmacol., 1997;338:111 -
Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots.
Thomas et al.
Neuropharmacology, 1998;37:1223
Product Datasheets
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Citation for (RS)-3,4-DCPG
The citations listed below are publications that use Tocris products. Selected citations for (RS)-3,4-DCPG include:
1 Citation: Showing 1 - 1
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mGluR8 modulates excitatory transmission in the bed nucleus of the stria terminalis in a stress-dependent manner.
Authors: Gosnell Et al.
Neuropsychopharmacology 2011;36:1599
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