Stavudine
Chemical Name: 1-[(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
Purity: ≥99%
Biological Activity
Stavudine is a nucleoside analog; antiviral that inhibits HIV replication in vitro. Orally bioavailable.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro.
Baba et al.
Biochem.Biophys.Res.Commun., 1987;142:128 -
Antiretroviral activity of stav. (2',3'-didehydro-3'-deoxythymidine, D4T).
Riddler et al.
Antiviral Res., 1995;27:189
Product Datasheets
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