VAL609 |
Number |
Title |
Journal |
Species |
Sample Types |
1 |
Sea buckthorn extract mitigates chronic obstructive pulmonary disease by suppression of ferroptosis via scavenging ROS and blocking p53/MAPK pathways |
J Ethnopharmacol. 2025 Jan 10:336:118726. |
Mouse |
serum |
2 |
Compact bone mesenchymal stem cells-derived paracrine mediators for cell-free therapy in sepsis |
Biochem Biophys Res Commun. 2024 Oct 1:727:150313 |
Mouse |
cell culture supernatants, tissue homogenates, serum |
3 |
Unveiling the potent effect of vitamin D: harnessing Nrf2/HO-1 signaling pathways as molecular targets to alleviate urban particulate matter-induced asthma inflammation |
BMC Pulm Med. 2024 Jan 25;24(1):55 |
Mouse |
BALF,serum |
4 |
Cannabidiol alleviates carbon tetrachloride-induced liver fibrosis in mice by regulating NF-κB and PPAR-α pathways. |
Exp Biol Med (Maywood). 2024 Apr 22:249:10141 |
Mouse |
serum |
5 |
MicroRNA-378 inhibits hepatocyte apoptosis during acute liver failure by targeting caspase-9 in mice |
Gastroenterol Hepatol. 2023 Feb;46(2):124-134 |
Mouse |
Serum |
6 |
Macrophage ferroportin serves as a therapeutic target against bacteria-induced acute lung injury by promoting barrier restoration |
iScience. 2022 Dec 1;25(12):105698 |
Mouse |
BALF |
7 |
Open-Ring Butenolides from a Marine-Derived Anti-Neuroinflammatory Fungus Aspergillus terreus Y10 |
Mar Drugs. 2018 Nov 2;16(11):428 |
Mouse |
Cell culture supernatant |
8 |
Fragments of bombinakinin M exist in lipopolysaccharide-stimulated skin secretions of Bombina maxima and show lipopolysaccharide-neutralizing activity |
J Immunol Methods. 2022 Oct:509:113343 |
Mouse |
Cell culture supernatant |
9 |
Anti-Inflammatory Effect of Acetone Extracts from Microalgae Chlorella sp. WZ13 on RAW264.7 Cells and TPA-induced Ear Edema in Mice |
Front. Mar. Sci., 05 July 2022 |
Mouse |
cells supernatant |
10 |
Programmed surface on poly(aryl-ether-ether-ketone) initiating immune mediation and fulfilling bone regeneration sequentially |
Innovation (Camb). 2021 Aug 5;2(3):100148 |
Mouse |
Cell culture supernatant |
11 |
Parthenolide targets NLRP3 to treat inflammasome-related diseases |
Int Immunopharmacol.2023 Jun:119:110229. |
Mouse |
serum, cell culture supernatants |
12 |
Phosphatidylglucose alleviates atherosclerosis by increasing cholesterol alienation to bile acids and cholesterol efflux in ApoE−/− mice |
J Sci Food Agric.2023 Aug 30;103(11):5529-5538. |
Mouse |
serum |
13 |
Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease |
Int J Mol Sci.2023 Mar 14;24(6):5549. |
Mouse |
serum |
14 |
Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair |
Reprod Sci.2023 Jun;30(6):1979-1993. |
Mouse |
plasma |
15 |
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages |
Int Immunopharmacol.2022 Dec;113(Pt A):109404. |
Mouse |
serum |
16 |
Mesenchymal stem cell-derived extracellular vesicles attenuate tPA-induced blood–brain barrier disruption in murine ischemic stroke models |
Acta Biomater.2022 Dec:154:424-442. |
Mouse |
cell culture supernatants |
17 |
Combined delivery of small molecule and protein drugs as synergistic therapeutics for treating corneal neovascularization by a one-pot coassembly strategy |
Mater Today Bio.2022 Oct 8:17:100456. |
Mouse |
Cell culture supernatants |
18 |
Taurine Alleviates Trimethylamine N-Oxide-Induced Atherosclerosis by Regulating Bile Acid Metabolism in ApoE-/- Mice |
J Agric Food Chem. 2022 May 11;70(18):5738-5747 |
Mouse |
serum |
19 |
Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation |
Acta Pharm Sin B. 2022 Feb;12(2):907-923 |
Mouse |
plasma |
20 |
Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model |
Front Immunol. 2022 Apr 13;13:878832 |
Mouse |
cell culture supernatants |
21 |
FGL2-MCOLN3-Autophagy Axis-Triggered Neutrophil Extracellular Traps Exacerbate Liver Injury in Fulminant Viral Hepatitis |
Cell Mol Gastroenterol Hepatol. 2022;14(5):1077-1101 |
Mouse |
serum |
22 |
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein |
Int Immunopharmacol. 2022 Oct;111:109148 |
Mouse |
serum |
23 |
Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation |
J. Med. Chem. 2022, 65, 1, 103–119 |
Mouse |
serum |
24 |
Carfilzomib modulates tumor microenvironment to potentiate immune checkpoint therapy for cancer |
EMBO Mol Med. 2022 Jan 11;14(1):e14502 |
Mouse |
cell culture supernatants |
25 |
Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β |
Front Pharmacol. 2022 Jun 14;13:911157 |
Mouse |
serum |
26 |
Anti-atherosclerotic effects of geraniin through the gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway in mice |
Phytomedicine. 2022 Jul;101:154104 |
Mouse |
plasma |
27 |
Activation of GIPR Exerts Analgesic and Anxiolytic-Like Effects in the Anterior Cingulate Cortex of Mice |
Front Endocrinol (Lausanne). 2022 May 30;13:887238 |
Mouse |
serum |
28 |
Ablation of GSDMD Attenuates Neurological Deficits and Neuropathological Alterations After Traumatic Brain Injury |
Front Cell Neurosci. 2022 May 20;16:915969 |
Mouse |
Tissue Lysates |
29 |
4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway |
J Cell Mol Med. 2022 Mar;26(5):1515-1529 |
Mouse |
cell culture supernatants |
30 |
The protective effect of cannabinoid type II receptor agonist AM1241 on ConA-induced liver injury in mice via mitogen-activated protein kinase signalling pathway |
Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211035251 |
Mouse |
Tissue Homogenates |
31 |
Shufeng Jiedu, a promising herbal therapy for moderate COVID-19:Antiviral and anti-inflammatory properties, pathways of bioactive compounds, and a clinical real-world pragmatic study |
Phytomedicine. 2021 May;85:153390 |
Mouse |
Tissue Homogenates |
32 |
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target |
Cell Res. 2021 Aug;31(8):847-860 |
Mouse |
serum,cell culture supernatants |
33 |
Multiscale Co-reconstruction of Lung Architectures and Inhalable Materials Spatial Distribution |
Adv Sci (Weinh). 2021 Feb 8;8(8):2003941 |
Mouse |
cell culture supernatants |
34 |
Anti-atopic effect of Viola yedoensis ethanol extract against 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction |
J Ethnopharmacol. 2021 Nov 15;280:114474 |
Mouse |
serum |
35 |
A two-adjuvant multiantigen candidate vaccine induces superior protective immune responses against SARS-CoV-2 challenge |
Cell Rep. 2021 Dec 14;37(11):110112 |
Mouse |
cell culture supernatants |
36 |
A more defective substrate leads to a less defective passive layer: Enhancing the mechanical strength, corrosion resistance and anti-inflammatory response of the low-modulus Ti-45Nb alloy by grain refinement |
Acta Biomater. 2021 May;126:524-536 |
Mouse |
cell culture supernatants |
37 |
Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes |
J Neuroinflammation. 2020 Feb 5;17(1):50 |
Mouse |
cell culture medium |
38 |
Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation |
Front Pharmacol. 2020 Oct 2;11:577319 |
Mouse |
cell culture supernatants |
39 |
Evaluation of His6-Metal Assemblies as a Drug Delivery Vehicle in the Treatment of Anterior Segment Disease Using a Corneal Inflammation Model |
ACS Biomater Sci Eng. 2020 Jul 13;6(7):4012-4023 |
Mouse |
cell culture supernatants |
40 |
Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1 |
Pathog Dis. 2020 Mar 1;78(2):ftaa016 |
Mouse |
serum |
41 |
Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury |
J Neurotrauma. 2019 Mar 19;36(6):903-918 |
Mouse |
cell culture supernatants |
42 |
MicroRNA‑93 inhibits chondrocyte apoptosis and inflammation in osteoarthritis by targeting the TLR4/NF‑κB signaling pathway |
Int J Mol Med. 2019 Feb;43(2):779-790 |
Mouse |
cell culture supernatants |
43 |
ALS-Associated E478G Mutation in Human OPTN (Optineurin) Promotes Inflammation and Induces Neuronal Cell Death |
Front Immunol. 2018 Nov 14;9:2647 |
Mouse |
cell culture supernatants,Tissue |
44 |
Resolvin D1 attenuates imiquimod-induced mice psoriasiform dermatitis through MAPKs and NF-κB pathways |
J Dermatol Sci. 2018 Feb;89(2):127-135 |
Mouse |
serum |
45 |
miR-155 Aggravates Liver Ischemia/reperfusion Injury by Suppressing SOCS1 in Mice |
Transplant Proc. 2018 Dec;50(10):3831-3839 |
Mouse |
serum, cell culture supernatants |
46 |
PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury |
Mediators Inflamm. 2018 Oct 3;2018:6757368 |
Mouse |
BALF |
47 |
microRNA-182-5p alleviates spinal cord injury by inhibiting inflammation and apoptosis through modulating the TLR4/NF-κB pathway |
Int J Clin Exp Pathol. 2018 Jun 1;11(6):2948-2958 |
Mouse |
cell culture supernatants |
48 |
Poly(dopamine)-modified carbon nanotube multilayered film and its effects on macrophages |
Carbon.Volume 113, March 2017, Pages 176-191 |
Mouse |
cell culture supernatants |
49 |
Mir-24 regulates hepatocyte apoptosis via BIM during acute liver failure |
Am J Transl Res. 2017 Nov 15;9(11):4925-4935 |
Mouse |
serum |
50 |
MicroRNA-182-5p Ameliorates Liver Ischemia-Reperfusion Injury by Suppressing Toll-Like Receptor 4 |
Transplant Proc. 2016 Oct;48(8):2809-2814 |
Mouse |
serum, cell culture supernatants |
51 |
CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment |
Sci Rep. 2015 Nov 3;5:15948 |
Mouse |
Serum |
52 |
miR-146a ameliorates liver ischemia/reperfusion injury by suppressing IRAK1 and TRAF6 |
PLoS One. 2014 Jul 2;9(7):e101530 |
Mouse |
cell culture supernatants |
53 |
Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells |
J Ethnopharmacol. 2013 Jun 21;148(1):271-6 |
Mouse |
cell culture supernatants |