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Yoda 2

Catalog #: 8051 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8051/5
Yoda 2 | PIEZO1
1 Image
Description: Piezo1 channel activator

Chemical Name: Potassium 4-(5-((2,6-dichlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)benzoate

Purity: ≥97%

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Biological Activity

Yoda 2 is a selective Piezo1 channel activator (EC50 values are 150 nM and 1.14 μM in mPiezo1 and HUVEC cells respectively). Increases Ca2+ signaling 2.8 fold in hPIEZO-TREx and 1.2 fold in mPIEZO1-TREx, compared to Yoda 1 (Cat. No. 5586). Induces concentration-dependent relaxation of mouse portal vein (EC50 = 1.2 μM). Suitable for use in vivo and in vitro.

Technical Data

M.Wt:
435.38
Formula:
C16H9Cl2N2O2S2K
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥97%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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