Human/Mouse/Rat SOX2 Antibody Summary
Gly135-Met317
Accession # P48431
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
Detection of SOX2 in Human Glioblastoma via seqIF™ staining on COMET™ SOX2 Antibody was detected in immersion fixed paraffin-embedded sections of human Glioblastoma using Mouse Anti-Human SOX2, Monoclonal Antibody (Catalog # MAB2018) at 5ug/mL at 37 ° Celsius for 4 minutes. Before incubation with the primary antibody, tissue underwent an all-in-one dewaxing and antigen retrieval preprocessing using PreTreatment Module (PT Module) and Dewax and HIER Buffer H (pH 9; Epredia Catalog # TA-999-DHBH). Tissue was stained using the Alexa Fluor™ 647 Goat anti-Mouse IgG Secondary Antibody at 1:200 at 37 ° Celsius for 2 minutes. (Yellow; Lunaphore Catalog # DR647MS) and counterstained with DAPI (blue; Lunaphore Catalog # DR100). Specific staining was localized to the nucleus. Protocol available in COMET™ Panel Builder.
E‑Cadherin and SOX2 in BG01V Human Stem Cells. E-Cadherin and SOX2 were detected in BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human E-Cadherin Antigen Affinity-purified Polyclonal Antibody (AF648) and 10 µg/mL Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for E-Cadherin using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and for SOX2 using the NorthernLights 493-conjugated Anti-Mouse Secondary Antibody (green; NL009). Cells were counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Detection of Human, Mouse, and Rat SOX2 by Western Blot. Western blot shows lysates of NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, D3 mouse embryonic stem cell line, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (HAF018). A specific band was detected for SOX2 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.
SOX2 in BG01V Human Embryonic Stem Cells. SOX2 was detected in immersion fixed BG01V human embryonic stem cells using Mouse Anti-Human/ Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (yellow; NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Detection of SOX2 in NTera‑2 Human Cell Line by Flow Cytometry. NTera-2 human testicular embryonic carcinoma cell line was stained with Mouse Anti-Human/ Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018, filled histogram) or isotype control antibody (MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (F0102B). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (FC005). View our protocol for Staining Intracellular Molecules.
Detection of Human SOX2 by Simple WesternTM. Simple Western lane view shows lysates of BG01V human embryonic stem cells, loaded at 0.2 mg/mL. A specific band was detected for SOX2 at approximately 50 kDa (as indicated) using 4 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.
Detection of SOX2 in glioblastoma. SOX2 was detected in immersion fixed paraffin-embedded sections of glioblastoma using Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC001). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to nuclei in cancer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.
Detection of Human SOX2 by Western Blot Western blotting analysis of the different antigens studied in cell lines (NS and AC) and in primary tumors. (a) Stemness antigens and differentiation antigens prevail in NS and AC, respectively. (b) Densitometric quantification of bands in NS and in the corresponding primary tumors. (c) Densitometric quantification of bands in AC and in the corresponding primary tumors. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/21869887), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Double immunofluorescence staining of core and periphery in orthotopic model with five different patient derived GBM spheroid cultures.Tissues were stained with Dapi (blue), Vimentin (green) and Sox-2 (red), Bmi-1 (red) and Glut-3 (red). The software-based classifier is shown in the right column. The classifier illustrates tumor cells co-expressing markers of interest in yellow and tumor cells not co-expressing markers of interest in green. The fluorescence stainings were quantified in both central part and periphery for Sox-2 (G), Bmi-1 (H) and Glut-3 (I). Statistical comparison was performed using student’s t-test. Scalebar: 200μm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0155106), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Rat SOX2 by Immunocytochemistry/Immunofluorescence Soluble factors increase the numbers of Hes3+ cells in the adult rat hippocampus.(a) Treatment with the soluble factors induced a powerful increase in the number of Sox2+ cells in the hilus [Quantifications are from images taken from the tip of the hilus to approximately 1,300 micrometers towards the CA3 region – representative images are shown. Staining for the young neuron marker doublecortin (DCX) helps to visualize the subgranular zone]. (b) The same treatment also induced an increase in the numbers of Hes3+ cells in the hilus. (c) Sox2+ cells inside the hilus co-expressed Hes3; in contrast, Sox2+ cells in the subgranular zone did not co-express Hes3. (d,e) Quantification graphs of the increases in Sox2+ and Hes3+ cell numbers in the hilus (p<0.05). For the graph, the number of cells in the sham operated control animals was set to 100%. [Width of images: a, 650 micrometers; b, 650 micrometers]. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0051630), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Rat SOX2 by Immunocytochemistry/Immunofluorescence Soluble factors increase the numbers of Hes3+ cells in the adult rat hippocampus.(a) Treatment with the soluble factors induced a powerful increase in the number of Sox2+ cells in the hilus [Quantifications are from images taken from the tip of the hilus to approximately 1,300 micrometers towards the CA3 region – representative images are shown. Staining for the young neuron marker doublecortin (DCX) helps to visualize the subgranular zone]. (b) The same treatment also induced an increase in the numbers of Hes3+ cells in the hilus. (c) Sox2+ cells inside the hilus co-expressed Hes3; in contrast, Sox2+ cells in the subgranular zone did not co-express Hes3. (d,e) Quantification graphs of the increases in Sox2+ and Hes3+ cell numbers in the hilus (p<0.05). For the graph, the number of cells in the sham operated control animals was set to 100%. [Width of images: a, 650 micrometers; b, 650 micrometers]. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0051630), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Double immunofluorescence staining of core and periphery of patient glioblastomas.Histological sections were stained with Dapi (blue), IDH1 (green) and Sox-2 (red) (AA-BE), Bmi-1 (red) (CA-DE) and Glut-3 (red) (EA to FE). The software-based classifier is shown in the right column. The classifier illustrates tumor cells co-expressing markers of interest in yellow and tumor cells not co-expressing markers of interest in green. The fluorescence stainings were quantified in both core and periphery for Sox-2 (G,J), Bmi-1 (H,K) and Glut-3 (I,L). Statistical comparison was performed using student’s t-test and ANOVA, ** p< 0.01. Scalebar: 200μm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0155106), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Western Blot CEP-1347 induces the differentiation of cancer stem cells into non-cancer stem cells(A) Glioma stem cells (GS-Y01, GS-Y03, and GS-NCC01), pancreatic cancer stem cells (PANC-1 CSLC), and ovarian cancer stem cells (A2780 CSLC, and TOV21G CSLC) treated without (Control) or with CEP-1347 (300 nM for PANC-1 CSLC, 200 nM for the others) for 6 days were subjected to flow cytometric analysis of the cell-surface expression of CD133. Representative flow cytometric plots together with the percentages of CD133-positive cells are shown. (B) Cells treated as described in (A) were subjected to immunoblot analysis of the indicated proteins. (C) PANC-1 CSLC cells treated without (Control: lane 1) or with CEP-1347 (lane 2) for 6 days and those cultured in the presence of CEP-1347 for 6 days and then in its absence for the indicated days (lanes 3-5) were subjected to immunoblot analysis of the indicated proteins. Image collected and cropped by CiteAb from the following publication (https://www.oncotarget.com/lookup/doi/10.18632/oncotarget.22033), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Rat SOX2 by Immunocytochemistry/Immunofluorescence Fluoxetine inhibits the differentiation of hypothalamic neuroprogenitor cells.Hypothalamic neuroprogenitor cells were differentiated for 18 days, in the presence or absence of fluoxetine (1 µM). Representative confocal photomicrographs for mature neurons marker Neu-N (green) (A). Fluoxetine decreases the percentage of Neu-N positive cells and the incubation with Trk receptors inhibitor K252a (24 h) partially reverses this effect (B). Representative confocal photomicrographs for the progenitor cells marker SOX-2 (green) (C). Fluoxetine increases the percentage of SOX-2 positive cells and the incubation with K252a (24 h) does not change this effect (D). Fluoxetine does not up regulate the levels of neurotrophic factor BDNF but incubation with K252a (24 h) results in a compensatory increase of BDNF mRNA levels (E). DAPI (blue), nuclear staining. Mean ± SEM; n = 4/5; One-Way ANOVA; ns, p>0.05; *, p<0.05; ***, p<0.001 compared to control; NS, p>0.05, #, p<0.05 compared to fluoxetine. Scale bar: 50 µm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24598761), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Hes3 is a marker of normal and cancer human stem cells.(A–C) Hes3+ cell in the striatum of non-cancerous adult human brain tissue (blood vessels identified by RECA-1 expression), human hemangioblastoma (HBM) biopsy (HBM Hes3+ megakaryocytes shown), human glioblastoma multiforme (GBM) biopsy (Hes3 co-expressed with prominin). (D) Fetal cortical cells sorted for prominin express Sox2 and Hes3. (E) Enrichment for Sox2+ and Hes3+ cells by magnetic sorting using an anti-prominin antibody. (Size bar, 50 µm). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/20195471), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Double immunofluorescence staining of core and periphery of patient glioblastomas.Histological sections were stained with Dapi (blue), IDH1 (green) and Sox-2 (red) (AA-BE), Bmi-1 (red) (CA-DE) and Glut-3 (red) (EA to FE). The software-based classifier is shown in the right column. The classifier illustrates tumor cells co-expressing markers of interest in yellow and tumor cells not co-expressing markers of interest in green. The fluorescence stainings were quantified in both core and periphery for Sox-2 (G,J), Bmi-1 (H,K) and Glut-3 (I,L). Statistical comparison was performed using student’s t-test and ANOVA, ** p< 0.01. Scalebar: 200μm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0155106), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Immunohistochemistry of a parallel section of Figure 1. (a) Poor GFAP expression. (b) High Nestin expression. (c) SOX2 is highly expressed in nuclei of the external slope of circumscribed necrosis. (d) REST expression, all DAB. (e) CD133-positive area, frozen section. (f) Musashi-1-positive area. Scale bar 50 μm. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/21869887), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Neural induction of hPSCs. (a) Both hPSC culture and neural differentiation were performed on LN521 substrate. Cortical neurons were induced with dual SMAD inhibition, expanded in the presence of FGF2, and matured with support by a selection of neurotrophic factors. Neural progenitor cells (NPCs) could be cryopreserved at day 21 and plated at day 32 for final experiments, including microelectrode array (MEA) measurements. (b) Three different hPSC lines (one hESC line, 08/023 and two hiPSC lines, 10212.EURCCs and IMR90-4) were characterized for their efficiency in producing neuroectodermal cells in response to 12-day neural induction by dual SMAD inhibition. Cells were stained for pluripotency marker Oct4 at the pluripotent stage and after 12 days of neural induction. The presence of early neuroectodermal markers was evaluated with Sox2, FoxG1 and Pax6 staining. (c) After 21 days of differentiation, the culture contained vimentin- and Pax6-positive NPCs that could be cryopreserved. Additionally, the first Tbr2- and MAP2-positive neurons were detected at this time point. (d) The percentages of Pax6-positive cells were quantified at four time points of differentiation (mean ± s.e.m., n = 5–14, data derived from 1–3 independent differentiations). Statistical analysis was performed with the Mann-Whitney U test to compare differences between day 12 and day 46 within each hPSC line, and significant p-values are presented in the image. The scale bar is 50 µm in all images. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31748598), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human SOX2 by Immunocytochemistry/Immunofluorescence Double immunofluorescence staining of core and periphery in orthotopic model with five different patient derived GBM spheroid cultures.Tissues were stained with Dapi (blue), Vimentin (green) and Sox-2 (red), Bmi-1 (red) and Glut-3 (red). The software-based classifier is shown in the right column. The classifier illustrates tumor cells co-expressing markers of interest in yellow and tumor cells not co-expressing markers of interest in green. The fluorescence stainings were quantified in both central part and periphery for Sox-2 (G), Bmi-1 (H) and Glut-3 (I). Statistical comparison was performed using student’s t-test. Scalebar: 200μm. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0155106), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence Characterization of TRNDi009-C iPSC line. A) Left: phase contrast imaging of TRNDi009-C colonies grown on Geltrex at passage 6. Right: Representative immunofluorescent images of iPSCs positive for stem cell markers: SOX2, OCT4, NANOG, and SSEA4. Nucleus is labelled with Hoechst 33342 (blue). B) Cytogenetic analysis showing a normal karyotype (46, XX). C) Detection of heterozygous mutation of a p.L302P (c.905 T > C) in exon 2 of the SMPD1 gene. D) Flow cytometry analysis of pluripotency protein markers: NANOG and TRA-1–60. E) RT-PCR verification for the clearance of the Sendai virus from reprogrammed cells. Sendai virus vector transduced fibroblasts were used as a positive control. F) Pathological analysis of teratoma from TRNDi009-C iPSC, showing a normal ectodermal, mesodermal, and endodermal differentiation. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31132580), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Human/Mouse/Rat SOX2 Antibody by Immunocytochemistry/ Immunofluorescence Characterization of TRNDi007-B iPSC line.A) Left: Phase contrast imaging of TRNDi007-B colonies. Right: Representative immunofluorescent images of iPSCs showing expression of stem cell markers: SOX2, OCT4, SSEA-4, and NANOG. Nucleus is stained with Hoechst dye (in blue). B) Flow cytometry analysis of pluripotency protein markers: TRA-1-60, NANOG and SSEA-4. C) Cytogenetic analysis showing a normal karyotype (46, XY). D) Detection of homozygous mutation of c.2560 C > T in exon 18 of the GAA gene. E) RT-PCR verification of the clearance of Sendai virus from the reprogrammed cells. Sendai virus vector transduced fibroblasts was used as positive control. F) Histological analysis of teratomas produced by TRNDi007-B iPSCs. Representative images showing the presence of ectodermal, endodermal and mesodermal derivatives. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/31026687), licensed under a CC-BY license. Not internally tested by R&D Systems.
Detection of Human Human/Mouse/Rat SOX2 Antibody by Western Blot CEP-1347 induces the differentiation of cancer stem cells into non-cancer stem cells(A) Glioma stem cells (GS-Y01, GS-Y03, and GS-NCC01), pancreatic cancer stem cells (PANC-1 CSLC), and ovarian cancer stem cells (A2780 CSLC, and TOV21G CSLC) treated without (Control) or with CEP-1347 (300 nM for PANC-1 CSLC, 200 nM for the others) for 6 days were subjected to flow cytometric analysis of the cell-surface expression of CD133. Representative flow cytometric plots together with the percentages of CD133-positive cells are shown. (B) Cells treated as described in (A) were subjected to immunoblot analysis of the indicated proteins. (C) PANC-1 CSLC cells treated without (Control: lane 1) or with CEP-1347 (lane 2) for 6 days and those cultured in the presence of CEP-1347 for 6 days and then in its absence for the indicated days (lanes 3-5) were subjected to immunoblot analysis of the indicated proteins. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/29212273), licensed under a CC-BY license. Not internally tested by R&D Systems.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SOX2
SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-6).
- Graham, V. et al. (2003) Neuron 39:749.
- Avilion, A.A. et al. (2003) Genes Dev. 17:126.
- Kishi, M. et al. (2000) Development 127:791.
- Yuan, H. et al. (1995) Genes Dev. 9:2635.
- Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
- Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Product Datasheets
Citations for Human/Mouse/Rat SOX2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
284
Citations: Showing 1 - 10
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PDGF-AA and BDNF Promote Neural Stem Cell Differentiation.
Authors: Soltys J, Perrone C, Knight J, Mao-Draayer Y.
Lab Chip
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Visualization of individual cell division history in complex tissues using iCOUNT
Authors: A Denoth-Lip, BN Jaeger, T Liang, LN Royall, SE Chie, K Buthey, D Machado, VI Korobeynyk, M Kruse, CM Munz, A Gerbaulet, BD Simons, S Jessberger
Cell Stem Cell, 2021-09-14;0(0):.
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Immunohistochemistry in Investigative and Toxicologic Pathology
Authors: Janardhan KS, Jensen H, Clayton NP, Herbert RA
Toxicol Pathol.
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Dopaminergic neurons derived from human induced pluripotent stem cells survive and integrate into 6-OHDA-lesioned rats.
Authors: Cai J, Yang M, Poremsky E et al.
Stem Cells Dev
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Adipose-Derived Neural Stem Cells Combined with Acellular Dermal Matrix as a Neural Conduit Enhances Peripheral Nerve Repair
Authors: WZ Syu, DY Hueng, WL Chen, JY Chan, SG Chen, SM Huang
Cell Transplant, 2019-05-31;0(0):9636897198535.
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Molecular signatures to define spermatogenic cells in common marmoset (Callithrix jacchus).
Authors: Lin ZY, Imamura M, Sano C et al.
Reproduction;143(5):597-609.
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ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
Authors: DM Baron, AR Fenton, S Saez-Atien, A Giampetruz, A Sreeram, Shankarach, PJ Keagle, VR Doocy, NJ Smith, EW Danielson, M Andresano, MC McCormack, J Garcia, V Bercier, L Van Den Bo, JR Brent, C Fallini, BJ Traynor, ELF Holzbaur, JE Landers
Cell Reports, 2022-04-05;39(1):110598.
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Proliferation and Differentiation in the Adult Subventricular Zone Are Not Affected by CSF1R Inhibition
Authors: Kyle, J;Wu, M;Gourzi, S;Tsirka, SE;
Front Cell Neurosci
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Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States
Authors: AJ Collier, SP Panula, JP Schell, P Chovanec, A Plaza Reye, S Petropoulo, AE Corcoran, R Walker, I Douagi, F Lanner, PJ Rugg-Gunn
Cell Stem Cell, 2017-03-23;0(0):.
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Generation of four human induced pluripotent stem cell lines derived from patients with MPAN, subtype of NBIA, carrying the c.204_214del11 mutation in the C19orf12 gene
Authors: Krogulec, E;Dobosz, AM;Liszewska, E;Majchrowicz, L;Dobrzy?, A;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of a human induced pluripotent stem cell line (FDIBSi001-A) from a patient with ADNP syndrome carrying ADNP mutation (c. 2059 T>C)
Authors: Mengnan, W;Yan, C;Qiong, X;Man, X;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Immunocytochemistry -
Generation of SOX2ZsGreen reporter authentic porcine induced pluripotent stem cells
Authors: Reddy Yeddula, SG;Green, E;Sandmaeir, S;Jeoung, YH;Subramanyam, PN;Park, CH;Telugu, BP;
Stem cell research
Species: Porcine
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of human induced pluripotent stem cells carrying albumin-sfGFP reporter
Authors: Wang, J;Ye, D;Li, S;Lu, X;Chi, Y;Tang, C;Zhou, X;Chen, M;Zheng, Y;Ge, J;Zou, Q;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Immunocytochemistry -
Characterization of a human induced pluripotent stem cell line (FDCHi015-A) derived from PBMCs of a patient harbouring ALDOB mutation
Authors: Yin, T;Liao, Y;Li, X;Wang, H;Wu, B;Dong, X;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of a human induced pluripotent stem cell line from a patient with GM3 synthase deficiency using self-replicating RNA vector
Authors: Tonin, R;Feo, F;Falliano, S;Giunti, L;Calamai, M;Procopio, E;Mari, F;Sciruicchio, V;Conti, V;Fanelli, I;Bambi, F;Guerrini, R;Morrone, A;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
The MDM2-p53 Axis Represents a Therapeutic Vulnerability Unique to Glioma Stem Cells
Authors: Nakagawa-Saito, Y;Mitobe, Y;Togashi, K;Suzuki, S;Sugai, A;Takenouchi, S;Nakamura, K;Sonoda, Y;Kitanaka, C;Okada, M;
International journal of molecular sciences
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons
Authors: Chen, Y;Kuang, J;Niu, Y;Zhu, H;Chen, X;So, KF;Xu, A;Shi, L;
Neural regeneration research
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Dmd mdx mice have defective oligodendrogenesis, delayed myelin compaction and persistent hypomyelination
Authors: Arreguin, AJ;Shao, Z;Colognato, H;
Disease models & mechanisms
Species: Mouse
Sample Types: Whole Tissue
Applications: Immunohistochemistry -
Generation of a human induced pluripotent stem cell line (FDCHi012-A) from a patient with DYRK1A-related intellectual disability syndrome carrying DYRK1A mutation (c.1024G > T)
Authors: Ge, Y;Cheng, Y;Yin, T;Peng, X;Xiong, Z;Wu, B;Wang, H;Xiong, M;Zhou, W;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of the human induced pluripotent stem cell line (IBKMOLi003-A) from PBMCs of a vascular Ehlers-Danlos syndrome (vEDS) patient carrying the heterozygous nonsense mutation c.430C > T (p.Q105*) in the COL3A1 gene
Authors: Höpperger, S;Spathopoulou, A;Mayer-Suess, L;Suarez-Cubero, M;Sillaber, K;Spreiz, A;Kiechl, S;Edenhofer, F;Fellner, L;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, Immunocytochemistry -
Generation of induced pluripotent stem cell lines from two unrelated individuals with familial hypertrophic cardiomyopathy carrying the MYBPC3 missense c.1484G>A mutation
Authors: Ribeiro, M;Martins, S;Carvalho, T;Furtado, M;Sampaio Cabral, J;Brito, D;Carmo-Fonseca, M;da Rocha, ST;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC, Flow Cytometry -
Generation of an Alagille syndrome (ALGS) patient-derived induced pluripotent stem cell line (TRNDi032-A) carrying a heterozygous mutation (p.Cys682Leufs*7) in the JAG1 gene
Authors: Hatim, O;Pavlinov, I;Xu, M;Linask, K;Beers, J;Liu, C;Baumgärtel, K;Gilbert, M;Spinner, N;Chen, C;Zou, J;Zheng, W;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Truncated vitronectin with E-cadherin enables the xeno-free derivation of human embryonic stem cells
Authors: Souralova, T;Hulinova, D;Jeseta, M;Ventruba, P;Hampl, A;Koutna, I;
Scientific reports
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import
Authors: Mann, JR;McKenna, ED;Mawrie, D;Papakis, V;Alessandrini, F;Anderson, EN;Mayers, R;Ball, HE;Kaspi, E;Lubinski, K;Baron, DM;Tellez, L;Landers, JE;Pandey, UB;Kiskinis, E;
Science advances
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Propensity of Patient-Derived iPSCs for Retinal Differentiation: Implications for Autologous Cell Replacement
Authors: Jessica A Cooke, Andrew P Voigt, Michael A Collingwood, Nicholas E Stone, S Scott Whitmore, Adam P DeLuca et al.
Stem Cells Translational Medicine
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Mesenchymal properties of iPSC-derived neural progenitors that generate undesired grafts after transplantation
Authors: Miho Isoda, Tsukasa Sanosaka, Ryo Tomooka, Yo Mabuchi, Munehisa Shinozaki, Tomoko Andoh-Noda et al.
Communications Biology
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Expression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia
Authors: Funes, S;Gadd, DH;Mosqueda, M;Zhong, J;Jung, J;Shankaracharya, ;Unger, M;Cameron, D;Dawes, P;Keagle, PJ;McDonough, JA;Boopathy, S;Sena-Esteves, M;Lutz, C;Skarnes, WC;Lim, ET;Schafer, DP;Massi, F;Landers, JE;Bosco, DA;
bioRxiv : the preprint server for biology
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line (FDCHi010-A) from a patient with Xia-Gibbs syndrome carrying AHDC1 mutation (c.2062C�>�T)
Authors: Yin, T;Wu, B;Peng, T;Liao, Y;Jiao, S;Wang, H;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC, Flow Cytometry -
Elevated FOXG1 in glioblastoma stem cells cooperates with Wnt/?-catenin to induce exit from quiescence
Authors: Robertson, FL;O'Duibhir, E;Gangoso, E;Bressan, RB;Bulstrode, H;Marqu�s-Torrej�n, M�;Ferguson, KM;Blin, C;Grant, V;Alfazema, N;Morrison, GM;Pollard, SM;
Cell reports
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
IPSC-Derived Sensory Neurons Directing Fate Commitment of Human BMSC-Derived Schwann Cells: Applications in Traumatic Neural Injuries
Authors: Tam, KW;Wong, CY;Wu, KL;Lam, G;Liang, X;Wong, WT;Li, MT;Liu, WY;Cai, S;Shea, GK;Shum, DK;Chan, YS;
Cells
Species: Human
Sample Types: Whole Cells
Applications: Immunocytochemistry -
Generation of a homozygous GRIN2A gene knockout human embryonic stem cell line using CRISPR/Cas9 system
Authors: Luo, X;Yang, K;Jiang, M;Chen, T;Chi, Y;Ma, B;Lai, L;Zou, Q;
Stem cell research
Species: Human
Sample Types: Whole Cells
Applications: ICC, Flow Cytometry -
Loss of function of FIP200 in human pluripotent stem cell-derived neurons leads to axonal pathology and hyperactivity.
Authors: Jianbin W, Andreas Z, Nils B et al.
Transl Psychiatry.
-
Generation of induced pluripotent stem cell line (UKWNLi008) derived from a patient carrying a c.1678C>G variant in the transient receptor potential cation channel subfamily A member (TRPA1) gene potentially associated with small fiber neuropathy
Authors: NM Schottmann, K Klug, E Klopocki, N Üçeyler
Stem Cell Research, 2023-04-12;69(0):103094.
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICC -
Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine
Authors: Alain Aguirre-Vázquez, Fabiola Castorena-Torres, Beatriz Silva-Ramírez, Katia Peñuelas-Urquides, María Elena Camacho-Moll, Luis A. Salazar-Olivo et al.
Stem Cell Research & Therapy
-
YAP1 and WWTR1 expression inversely correlates with neuroendocrine markers in Merkel cell carcinoma
Authors: Thomas C. Frost, Ashley K. Gartin, Mofei Liu, Jingwei Cheng, Harita Dharaneeswaran, Derin B. Keskin et al.
Journal of Clinical Investigation
-
Generation of an induced pluripotent stem cell line from an aortic dissection patient carrying MCTP2/c.2635T�>�G mutation
Authors: W Feng, C Li, Y Li, J Yang, R Fan
Stem Cell Research, 2023-02-26;68(0):103058.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages
Authors: MF Wells, J Nemesh, S Ghosh, JM Mitchell, MR Salick, CJ Mello, D Meyer, O Pietilaine, F Piccioni, EJ Guss, K Raghunatha, M Tegtmeyer, D Hawes, A Neumann, KA Worringer, D Ho, S Kommineni, K Chan, BK Peterson, JJ Raymond, JT Gold, MT Siekmann, E Zuccaro, R Nehme, A Kaykas, K Eggan, SA McCarroll
Cell Stem Cell, 2023-02-15;0(0):.
Species: Human
Sample Types: Organoid, Whole Cells
Applications: ICC, IHC -
Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas
Authors: J Dougherty, K Harvey, A Liou, K Labella, D Moran, S Brosius, T De Raedt
PLoS ONE, 2023-02-02;18(2):e0277305.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Efficient generation of marmoset primordial germ cell-like cells using induced pluripotent stem cells
Authors: Yasunari Seita, Keren Cheng, John R McCarrey, Nomesh Yadu, Ian H Cheeseman, Alec Bagwell et al.
eLife
-
Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation
Authors: KW Govek, S Chen, P Sgourdou, Y Yao, S Woodhouse, T Chen, MV Fuccillo, DJ Epstein, PG Camara
Cell Reports, 2022-12-06;41(10):111768.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
CHRDL1 Regulates Stemness in Glioma Stem-like Cells
Authors: I Berglar, S Hehlgans, A Wehle, C Roth, C Herold-Men, F Rödel, D Kögel, B Linder
Cells, 2022-12-03;11(23):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain
Authors: Marcella Birtele, Petter Storm, Yogita Sharma, Janko Kajtez, Jenny Nelander Wahlestedt, Edoardo Sozzi et al.
Development
-
A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop
Authors: Z Xiao, G Shi, S Xi, AK Singh, J Willette-B, X Li, F Zhu, L Su, X Wu, DS Schrump, Y Hu
Cell Death & Disease, 2022-10-21;13(10):885.
Species: Moose
Sample Types: Cell Lysates
Applications: Western Blot -
The Manufacture of Xeno- and Feeder-Free Clinical-Grade Human Embryonic Stem Cell Lines: First Step for Cell Therapy
Authors: Tereza Souralova, Daniela Rehakova, Michal Jeseta, Lenka Tesarova, Jindrich Beranek, Pavel Ventruba et al.
International Journal of Molecular Sciences
-
Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for beta cell replacement
Authors: R Chimienti, T Baccega, S Torchio, F Manenti, S Pellegrini, A Cospito, A Amabile, MT Lombardo, P Monti, V Sordi, A Lombardo, M Malnati, L Piemonti
Cell Reports, 2022-09-27;40(13):111423.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
SerpinB3 drives cancer stem cell survival in glioblastoma
Authors: A Lauko, J Volovetz, SM Turaga, D Bayik, DJ Silver, K Mitchell, EE Mulkearns-, DC Watson, K Desai, M Midha, J Hao, K McCortney, A Steffens, U Naik, MS Ahluwalia, S Bao, C Horbinski, JS Yu, JD Lathia
Cell Reports, 2022-09-13;40(11):111348.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Spatial profiling of early primate gastrulation in utero
Authors: Sophie Bergmann, Christopher A. Penfold, Erin Slatery, Dylan Siriwardena, Charis Drummer, Stephen Clark et al.
Nature
-
p38 MAPK-dependent phosphorylation of transcription factor SOX2 promotes an adaptive response to BRAF inhibitors in melanoma cells
Authors: S Pietrobono, R De Paolo, D Mangiameli, A Marranci, I Battisti, C Franchin, G Arrigoni, D Melisi, L Poliseno, B Stecca
The Journal of Biological Chemistry, 2022-08-07;298(9):102353.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP, Immunoprecipitation -
Inhibition of the Phospholipase Cepsilon-c-Jun N-Terminal Kinase Axis Suppresses Glioma Stem Cell Properties
Authors: M Okada, Y Nakagawa-S, Y Mitobe, A Sugai, K Togashi, S Suzuki, C Kitanaka
International Journal of Molecular Sciences, 2022-08-07;23(15):.
Species: Mouse
Sample Types: Whole Cells
Applications: Western Blot -
A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development
Authors: V Benedetti, F Banfi, M Zaghi, R Moll-Diaz, L Massimino, L Argelich, E Bellini, S Bido, S Muggeo, G Ordazzo, G Mastrotota, M Moneta, A Sessa, V Broccoli
Science Advances, 2022-08-03;8(31):eabn3986.
Species: Human
Sample Types: Cell Lysate
Applications: Western Blot -
HDAC Class I Inhibitor Domatinostat Preferentially Targets Glioma Stem Cells over Their Differentiated Progeny
Authors: Y Nakagawa-S, S Saitoh, Y Mitobe, A Sugai, K Togashi, S Suzuki, C Kitanaka, M Okada
International Journal of Molecular Sciences, 2022-07-22;23(15):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient
Authors: J Lotila, T Hyvärinen, H Skottman, L Airas, S Narkilahti, S Hagman
Oncogene, 2022-07-11;63(0):102865.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCs
Authors: RR Khadim, RK Vadivelu, T Utami, FG Torizal, M Nishikawa, Y Sakai
International Journal of Molecular Sciences, 2022-06-30;23(13):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Changes in the Expression of Smooth Muscle Cell-Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell-Based Therapy for Male and Female Pattern Hair Loss
Authors: Y Yoshida, M Takahashi, H Yamanishi, Y Nakazawa, J Kishimoto, M Ohyama
International Journal of Molecular Sciences, 2022-06-27;23(13):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The 22q11.2 region regulates presynaptic gene-products linked to schizophrenia
Authors: Ralda Nehme, Olli Pietiläinen, Mykyta Artomov, Matthew Tegtmeyer, Vera Valakh, Leevi Lehtonen et al.
Nature Communications
-
MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels
Authors: Elisa Närvä, Maria E. Taskinen, Sergio Lilla, Aleksi Isomursu, Mika Pietilä, Jere Weltner et al.
iScience
-
Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening
Authors: LJ Flitsch, K Börner, C Stüllein, S Ziegler, V Sonntag-Bu, E Wiedtke, V Semkova, SWC Au Yeung, J Schlee, M Hajo, M Mathews, BS Ludwig, S Kossatz, H Kessler, D Grimm, O Brüstle
Scientific Reports, 2022-05-19;12(1):8356.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene
Authors: M Tisch, M Carmen De, M Suarez-Cub, C Fauth, M Defrancesc, J Zschocke, K Günther, F Edenhofer
Stem Cell Research, 2022-04-09;61(0):102784.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation and characterization of induced pluripotent stem cell line (IBBISTi004-A) from an Angelman syndrome patient carrying a class II deletion of the maternal chromosome 15q11.2-q13
Authors: C Maranga, C Pereira, AC Raposo, A Vieira, S Duarte, EP Bekman, I Milagre, ST da Rocha
Stem Cell Research, 2022-03-21;61(0):102757.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A�>�G of unknown pathogenicity in Fabry disease
Authors: M Breyer, T Klein, K Klug, E Klopocki, N Üçeyler
Stem Cell Research, 2022-03-14;61(0):102747.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Slow-Cycling Cells in Glioblastoma: A Specific Population in the Cellular Mosaic of Cancer Stem Cells
Authors: Changlin Yang, Guimei Tian, Mariana Dajac, Andria Doty, Shu Wang, Ji-Hyun Lee et al.
Cancers (Basel)
-
Differences in stem cell marker and osteopontin expression in primary and recurrent glioblastoma
Authors: B Polat, G Wohlleben, R Kosmala, D Lisowski, F Mantel, V Lewitzki, M Löhr, R Blum, P Herud, M Flentje, CM Monoranu
Cancer Cell International, 2022-02-19;22(1):87.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Smoothened/AMP-Activated Protein Kinase Signaling in Oligodendroglial Cell Maturation
Authors: A Del Giovan, M Russo, L Tirou, H Faure, M Ruat, S Balestri, C Sposato, F Basoli, A Rainer, A Kassoussi, E Traiffort, A Ragnini-Wi
Frontiers in Cellular Neuroscience, 2022-01-10;15(0):801704.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
G-quadruplex DNA structures in human stem cells and differentiation
Authors: KG Zyner, A Simeone, SM Flynn, C Doyle, G Marsico, S Adhikari, G Portella, D Tannahill, S Balasubram
Nature Communications, 2022-01-10;13(1):142.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats
Authors: IC Han, LR Bohrer, KN Gibson-Cor, LA Wiley, A Shrestha, BE Harman, C Jiao, EH Sohn, R Wendland, BN Allen, KS Worthingto, RF Mullins, EM Stone, BA Tucker
Cell Transplantation, 2022-01-01;31(0):9636897221104.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Growth factors with valproic acid restore injury-impaired hearing by promoting neuronal regeneration
Authors: Takahiro Wakizono, Hideyuki Nakashima, Tetsuro Yasui, Teppei Noda, Kei Aoyagi, Kanako Okada et al.
JCI Insight
-
Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids
Authors: M Notaras, A Lodhi, F Dündar, P Collier, NM Sayles, H Tilgner, D Greening, D Colak
Molecular Psychiatry, 2021-11-17;0(0):.
Species: Human
Sample Types: Organoid
Applications: IHC -
Targeting Folate Metabolism Is Selectively Cytotoxic to Glioma Stem Cells and Effectively Cooperates with Differentiation Therapy to Eliminate Tumor-Initiating Cells in Glioma Xenografts
Authors: Okada M, Suzuki S, Togashi K et al.
International Journal of Molecular Sciences
-
Induction of inverted morphology in brain organoids by vertical-mixing bioreactors
Authors: Dang Ngoc Anh Suong, Keiko Imamura, Ikuyo Inoue, Ryotaro Kabai, Satoko Sakamoto, Tatsuya Okumura et al.
Communications Biology
-
The Structure of the Spinal Cord Ependymal Region in Adult Humans Is a Distinctive Trait among Mammals
Authors: Alejandro Torrillas de la Cal, Beatriz Paniagua-Torija, Angel Arevalo-Martin, Christopher Guy Faulkes, Antonio Jesús Jiménez, Isidre Ferrer et al.
Cells
-
Transplantable human motor networks as a neuron-directed strategy for spinal cord injury
Authors: Zachary T. Olmsted, Cinzia Stigliano, Annalisa Scimemi, Tatiana Wolfe, Jose Cibelli, Philip J. Horner et al.
iScience
-
High Glycolytic Activity Enhances Stem Cell Reprogramming of Fahd1-KO Mouse Embryonic Fibroblasts
Authors: Ahmad Salti, Solmaz Etemad, Marta Suarez Cubero, Eva Albertini, Beata Kovacs-Szalka, Max Holzknecht et al.
Cells
-
Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
Authors: F Pecori, N Kondo, C Ogura, T Miura, M Kume, Y Minamijima, K Yamamoto, S Nishihara
Cell Reports, 2021-07-13;36(2):109361.
Species: Human, Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936�T�>�A) mutation in JAGGED-1
Authors: BM Brooks, M Pradhan, YS Cheng, K Gorshkov, A Farkhondeh, CZ Chen, J Beers, C Liu, K Baumgaerte, S Rodems, W Zheng
Stem Cell Research, 2021-06-24;54(0):102447.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids
Authors: M Notaras, A Lodhi, E Barrio-Alo, C Foord, T Rodrick, D Jones, H Fang, D Greening, D Colak
Molecular Psychiatry, 2021-06-22;0(0):.
Species: Human
Sample Types: Organoids
Applications: IHC -
Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls
Authors: L Ma, M Schmidt, EM Morrow
Stem Cell Research, 2021-06-18;54(0):102435.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability
Authors: F Xiong, R Wang, JH Lee, S Li, SF Chen, Z Liao, LA Hasani, PT Nguyen, X Zhu, J Krakowiak, DF Lee, L Han, KL Tsai, Y Liu, W Li
Cell Research, 2021-06-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G�>�A in the ACVR1 gene
Authors: X Huang, A Roeder, R Li, J Beers, C Liu, J Zou, PB Yu, W Zheng
Stem Cell Research, 2021-06-07;54(0):102424.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway
Authors: YC Lin, MS Kumar, N Ramesh, EN Anderson, AT Nguyen, B Kim, S Cheung, JA McDonough, WC Skarnes, R Lopez-Gonz, JE Landers, NL Fawzi, IRA Mackenzie, EB Lee, JA Nickerson, D Grunwald, UB Pandey, DA Bosco
Nature Neuroscience, 2021-05-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division
Authors: Sergi Junyent, Joshua C Reeves, James LA Szczerkowski, Clare L Garcin, Tung-Jui Trieu, Matthew Wilson et al.
eLife
-
An induced pluripotent stem cell line (NCATS-CL9075) from a patient carrying compound heterozygote mutations, p.R390P and p.L318P, in the NGLY1 gene
Authors: M Pradhan, A Farkhondeh, YS Cheng, M Xu, J Beers, J Zou, C Liu, M Might, S Rodems, K Baumgärtel, W Zheng
Stem Cell Research, 2021-05-20;54(0):102400.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration
Authors: MS Lee, MJ Stebbins, H Jiao, HC Huang, EM Leiferman, BE Walczak, SP Palecek, EV Shusta, WJ Li
Science Advances, 2021-05-19;7(21):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an induced pluripotent stem cell line (TRNDi030-A) from a patient with Farber disease carrying a homozygous p. Y36C (c. 107 A>G) mutation in ASAH1
Authors: BM Brooks, CD Yeh, J Beers, C Liu, YS Cheng, K Gorshkov, J Zou, W Zheng, CZ Chen
Stem Cell Research, 2021-05-12;53(0):102387.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of Alagille syndrome derived induced pluripotent stem cell line carrying heterozygous mutation in the JAGGED-1 gene at splicing site (Chr20: 10,629,709C>A) before exon 11
Authors: W Zhu, YS Cheng, M Xu, A Farkhondeh, J Beers, J Zou, C Liu, K Baumgaerte, S Rodems, W Zheng
Stem Cell Research, 2021-04-27;53(0):102366.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation
Authors: TP Silva, CA Pereira, AC Raposo, AR Oliveira, M Arez, JMS Cabral, I Milagre, M Carmo-Fons, STD Rocha
Stem Cell Research, 2021-04-23;53(0):102364.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis
Authors: MA Khuu, T Nallamothu, CI Castro-Riv, A Arias-Cavi, CC Szujewski, AJ Garcia Iii
Scientific Reports, 2021-03-16;11(1):6005.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
A Micropatterned Human‐Specific Neuroepithelial Tissue for Modeling Gene and Drug‐Induced Neurodevelopmental Defects
Authors: Geetika Sahni, Shu‐Yung Chang, Jeremy Teo Choon Meng, Jerome Zu Yao Tan, Jean Jacques Clement Fatien, Carine Bonnard et al.
Advanced Science
-
Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
Authors: RB Bressan, B Southgate, KM Ferguson, C Blin, V Grant, N Alfazema, JC Wills, MA Marques-To, GM Morrison, J Ashmore, F Robertson, CAC Williams, L Bradley, A von Kriegs, RA Anderson, SR Tomlinson, SM Pollard
Cell Stem Cell, 2021-02-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA
Authors: TP Silva, CA Pereira, AR Oliveira, AC Raposo, M Arez, JMS Cabral, I Milagre, M Carmo-Fons, ST da Rocha
Stem Cell Research, 2021-02-11;52(0):102242.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties
Authors: V Pasquale, G Ducci, G Campioni, A Ventrici, C Assalini, S Busti, M Vanoni, R Vago, E Sacco
Cells, 2020-12-11;9(12):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons
Authors: ST Chen, WJ Lai, WJ Zhang, QP Chen, LB Zhou, KF So, LL Shi
Neural Regen Res, 2020-12-01;15(12):2335-2343.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Investigation of de novo mutations in a schizophrenia case-parent trio by induced pluripotent stem cell-based in vitro disease modeling: convergence of schizophrenia- and autism-related cellular phenotypes
Authors: Edit Hathy, Eszter Szabó, Nóra Varga, Zsuzsa Erdei, Csongor Tordai, Boróka Czehlár et al.
Stem Cell Research & Therapy
-
Functional Comparison of Blood-Derived Human Neural Progenitor Cells
Authors: Eszter Szabó, Flóra Juhász, Edit Hathy, Dóra Reé, László Homolya, Zsuzsa Erdei et al.
International Journal of Molecular Sciences
-
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL
Authors: S Pietrobono, G Anichini, C Sala, F Manetti, LL Almada, S Pepe, RM Carr, BD Paradise, JN Sarkaria, JI Davila, L Tofani, I Battisti, G Arrigoni, L Ying, C Zhang, H Li, A Meves, ME Fernandez-, B Stecca
Nat Commun, 2020-11-17;11(1):5865.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Generation of an induced pluripotent stem cell line from an Alstr�m Syndrome patient with ALMS1 mutation (c.3902C�>�A, c.6436C�>�T) and a gene correction isogenic iPSC line
Authors: X Ji, Q Tang, C Tang, Z Wu, L Ma, X Guo, G Cheng, Y Chen, T Yang, M Xiong, W Zhou
Stem Cell Res, 2020-11-17;49(0):102089.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis
Authors: F Pecori, Y Akimoto, H Hanamatsu, JI Furukawa, Y Shinohara, Y Ikehara, S Nishihara
J. Cell. Sci., 2020-10-23;0(0):.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Four induced pluripotent stem cell lines (TRNDi021-C, TRNDi023-D, TRNDi024-D and TRNDi025-A) generated from fibroblasts of four healthy individuals
Authors: X Xu, M Pradhan, M Xu, YS Cheng, J Beers, KL Linask, Y Lin, W Zheng, J Zou
Stem Cell Res, 2020-10-01;49(0):102011.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons
Authors: Feline W Lindhout, Robbelien Kooistra, Sybren Portegies, Lotte J Herstel, Riccardo Stucchi, Basten L Snoek et al.
eLife
-
Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome
Authors: SR Sripathy, Y Wang, RL Moses, A Fatemi, DA Batista, BJ Maher
Stem Cell Res, 2020-09-17;48(0):102001.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics
Authors: AA Zalenski, S Majumder, K De, M Venere
Sci Rep, 2020-08-18;10(1):13946.
Species: Human
Sample Types: Complex Sample Type, Whole Tissue
Applications: IHC -
Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
Authors: L Muzio, R Sirtori, D Gornati, S Eleuteri, A Fossaghi, D Brancaccio, L Manzoni, L Ottoboni, L Feo, A Quattrini, E Mastrangel, L Sorrentino, E Scalone, G Comi, L Marinelli, N Riva, M Milani, P Seneci, G Martino
Nat Commun, 2020-07-31;11(1):3848.
Species: Mouse
Sample Types: Whole Cells, Whole Tissue
Applications: ICC, IHC -
The self-renewal dental pulp stem cell microtissues challenged by a toxic dental monomer
Authors: G Kaufman, NM Kiburi, D Skrtic
Biosci. Rep., 2020-06-26;40(6):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
Authors: M Mehdipour, C Skinner, N Wong, M Lieb, C Liu, J Etienne, C Kato, D Kiprov, MJ Conboy, IM Conboy
Aging (Albany NY), 2020-05-30;12(10):8790-8819.
-
Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer
Authors: I Gomes, BP de Almeida, S Dâmaso, A Mansinho, I Correia, S Henriques, R Cruz-Duart, G Vilhais, P Félix, P Alves, P Corredeira, NL Barbosa-Mo, L Costa, S Casimiro
Oncotarget, 2020-05-12;11(19):1714-1728.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
Cell Rep, 2020-05-05;31(5):107599.
Species: Human
Sample Types:
Applications: IF -
Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells
Authors: R Kitajima, R Nakai, T Imamura, T Kameda, D Kozuka, H Hirai, H Ito, H Imai, M Imamura
Stem Cell Res, 2020-02-28;44(0):101749.
Species: Pan troglodytes (Chimpanzee)
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (TRNDi001-D) from a Niemann-Pick disease type C1 (NPC1) patient carrying a homozygous p. I1061T (c. 3182T>C) mutation in the NPC1 gene
Authors: R Li, M Pradhan, M Xu, A Roeder, J Beers, J Zou, C Liu, FD Porter, W Zheng
Stem Cell Res, 2020-02-19;44(0):101737.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain
Authors: L Su, X Lei, H Ma, C Feng, J Jiang, J Jiao
Cell Death Differ., 2020-02-03;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy
Authors: H Hengel, C Bosso-Lefè, G Grady, E Szenker-Ra, H Li, S Pierce, É Lebigot, TT Tan, MY Eio, G Narayanan, KH Utami, M Yau, N Handal, W Deigendesc, R Keimer, HM Marzouqa, M Gunay-Aygu, MJ Muriello, H Verhelst, S Weckhuysen, S Mahida, S Naidu, TG Thomas, JY Lim, ES Tan, D Haye, MAAP Willemsen, R Oegema, WG Mitchell, TM Pierson, MV Andrews, MC Willing, LH Rodan, TS Barakat, M van Slegte, RH Gavrilova, D Martinelli, T Gilboa, AM Tamim, MO Hashem, MD AlSayed, MM Abdulrahim, M Al-Owain, A Awaji, AAH Mahmoud, EA Faqeih, AA Asmari, SM Algain, LA Jad, HM Aldhalaan, I Helbig, DA Koolen, A Riess, I Kraegeloh-, P Bauer, S Gulsuner, H Stamberger, AYJ Ng, S Tang, S Tohari, B Keren, LE Schultz-Ro, EW Klee, S Barresi, M Tartaglia, H Mor-Shaked, S Maddirevul, A Begtrup, A Telegrafi, R Pfundt, R Schüle, B Ciruna, C Bonnard, MA Pouladi, JC Stewart, A Claridge-C, DJ Lefeber, FS Alkuraya, AS Mathuru, B Venkatesh, JJ Barycki, MA Simpson, SS Jamuar, L Schöls, B Reversade
Nat Commun, 2020-01-30;11(1):595.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Characterization of Influenza A Virus Infection in Mouse Pulmonary Stem/Progenitor Cells
Authors: Tai-Ling Chao, Sing-Yi Gu, Pi-Han Lin, Yu-Tien Chou, Thai-Yen Ling, Sui-Yuan Chang
Frontiers in Microbiology
-
A dorsal-ventral gradient of Wnt3a/ beta -catenin signals controls mouse hindgut extension and colon formation
Authors: Robert J. Garriock, Ravindra B. Chalamalasetty, JianJian Zhu, Mark W. Kennedy, Amit Kumar, Susan Mackem et al.
Development
-
Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures
Authors: T Hyvärinen, A Hyysalo, FE Kapucu, L Aarnos, A Vinogradov, SJ Eglen, L Ylä-Outine, S Narkilahti
Sci Rep, 2019-11-20;9(1):17125.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of long QT syndrome type 1
Authors: M Mura, F Bastaroli, M Corli, M Ginevrino, F Calabrò, M Boni, L Crotti, EM Valente, PJ Schwartz, M Gnecchi
Stem Cell Res, 2019-11-20;42(0):101658.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs
Authors: E Grall, V Gourain, A Naïr, E Martin, MC Birling, JN Freund, I Duluc
Cell Death Dis, 2019-10-24;10(11):812.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Regulation of Cyclin E by transcription factors of the naïve pluripotency network in mouse embryonic stem cells
Authors: Fabrice Gonnot, Diana Langer, Pierre-Yves Bourillot, Nathalie Doerflinger, Pierre Savatier
Cell Cycle
-
Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
Authors: A Stubb, C Guzmán, E Närvä, J Aaron, TL Chew, M Saari, M Miihkinen, G Jacquemet, J Ivaska
Nat Commun, 2019-10-18;10(1):4756.
Species: Human
Sample Types: Whole Cells
Applications: Western Blot -
ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation
Authors: NM Peñaranda-, C Meijer, Y Liang, BM Dijkstra, R Aguirre-Ga, WFA den Dunnen, FAE Kruyt
Cell Death Dis, 2019-09-18;10(10):690.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Expanded potential stem cell media as a tool to study human developmental hematopoiesis in vitro
Authors: Adam C. Wilkinson, David J. Ryan, Iwo Kucinski, Wei Wang, Jian Yang, Sonia Nestorowa et al.
Experimental Hematology
-
An induced pluripotent stem cell line (TRNDi010-C) from a patient carrying a homozygous p.R401X mutation in the NGLY1 gene
Authors: S Yang, YS Cheng, R Li, M Pradhan, J Hong, J Beers, J Zou, C Liu, M Might, S Rodems, W Zheng
Stem Cell Res, 2019-07-09;39(0):101496.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations
Authors: J Yao, X Wu, D Zhang, L Wang, L Zhang, EX Reynolds, C Hernandez, KI Boström, Y Yao
J. Clin. Invest., 2019-06-24;130(0):.
Species: Human, Mouse
Sample Types: Tissue Homogenates, Whole Cells
Applications: ChIP, ChIP-Seq, Flow Cytometry, ICC, Western Blot -
A six-inhibitor culture medium for improving naïve-type pluripotency of porcine pluripotent stem cells
Authors: Ye Yuan, Jinkyu Park, Yuchen Tian, Jungmin Choi, Rolando Pasquariello, Andrei P. Alexenko et al.
Cell Death Discovery
-
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
Authors: M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, T Zheng, EK Nash, LK McHenry, Z An, F Ye, Y Takashima, J Clarke, H Ayetey, FMG Cavalli, B Luu, BS Moriarity, S Ilkhanizad, L Chavez, C Yu, KM Kurian, T Magnaldo, N Sevenet, P Koch, SM Pollard, P Dirks, MP Snyder, DA Largaespad, YJ Cho, JJ Phillips, FJ Swartling, AS Morrissy, M Kool, SM Pfister, MD Taylor, A Smith, WA Weiss
Cell Stem Cell, 2019-06-13;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming
Authors: Zhiwei Luo, Xiaobing Qing, Christina Benda, Zhijian Huang, Meng Zhang, Yinghua Huang et al.
Cell Regeneration
-
Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner
Authors: L Zurkirchen, S Varum, S Giger, A Klug, J Häusel, R Bossart, M Zemke, C Cantù, ZK Atak, N Zamboni, K Basler, L Sommer
Nat Commun, 2019-05-16;10(1):2192.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
An induced pluripotent stem cell line (TRNDi009-C) from a Niemann-Pick disease type A patient carrying a heterozygous p.L302P (c.905 T>C) mutation in the SMPD1 gene
Authors: A Baskfield, R Li, J Beers, J Zou, C Liu, W Zheng
Stem Cell Res, 2019-05-15;38(0):101461.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line
Authors: S Howden, H Hosseini F, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman
Stem Cell Res, 2019-05-04;38(0):101453.
Species: Human
Sample Types: Whole Cells
-
CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons
Authors: C Calatayud, G Carola, I Fernández-, M Valtorta, S Jiménez-De, M Díaz, J Soriano-Fr, G Cappellett, J García-San, Á Raya, A Consiglio
Sci Rep, 2019-05-02;9(1):6811.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene
Authors: J Hong, M Xu, R Li, YS Cheng, J Kouznetsov, J Beers, C Liu, J Zou, W Zheng
Stem Cell Res, 2019-04-25;37(0):101451.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
User-defined morphogen patterning for directing human cell fate stratification
Authors: MC Regier, JJ Tokar, JW Warrick, L Pabon, E Berthier, DJ Beebe, KR Stevens
Sci Rep, 2019-04-23;9(1):6433.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of the human induced pluripotent stem cell (hiPSC) line PSMi005-A from a patient carrying the KCNQ1-R190W mutation
Authors: M Mura, YK Lee, F Pisano, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
Stem Cell Res, 2019-04-13;37(0):101437.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene
Authors: A Baskfield, R Li, J Beers, J Zou, C Liu, W Zheng
Stem Cell Res, 2019-04-12;37(0):101436.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A human induced pluripotent stem cell line (TRNDi007-B) from an infantile onset Pompe patient carrying p.R854X mutation in the GAA gene
Authors: YS Cheng, R Li, A Baskfield, J Beers, J Zou, C Liu, W Zheng
Stem Cell Res, 2019-04-11;37(0):101435.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness
Authors: SFB Fadhlullah, NBA Halim, JYT Yeo, RLY Ho, P Um, BT Ang, C Tang, WH Ng, DM Virshup, IAW Ho
Oncogene, 2019-04-09;38(27):5367-5380.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Generation of the human induced pluripotent stem cell (hiPSC) line PSMi004-A from a carrier of the KCNQ1-R594Q mutation
Authors: M Mura, YK Lee, F Pisano, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
Stem Cell Res, 2019-03-27;37(0):101431.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene
Authors: W Huang, M Xu, R Li, A Baskfield, J Kouznetsov, J Beers, J Zou, C Liu, W Zheng
Stem Cell Res, 2019-03-23;37(0):101427.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma
Authors: M Sherman-Sa, H Onallah, A Holth, R Reich, B Davidson
Gynecol. Oncol., 2019-03-21;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma
Authors: BW Stringer, BW Day, RCJ D'Souza, PR Jamieson, KS Ensbey, ZC Bruce, YC Lim, K Goasdoué, C Offenhäuse, S Akgül, S Allan, T Robertson, P Lucas, G Tollesson, S Campbell, C Winter, H Do, A Dobrovic, PL Inglis, RL Jeffree, TG Johns, AW Boyd
Sci Rep, 2019-03-20;9(1):4902.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death
Authors: MA Ajmone-Cat, A Onori, C Toselli, E Stronati, M Morlando, I Bozzoni, E Monni, Z Kokaia, G Lupo, L Minghetti, S Biagioni, E Cacci
Sci Rep, 2019-03-14;9(1):4572.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Uncovering the Functional Link Between SHANK3 Deletions and Deficiency in Neurodevelopment Using iPSC-Derived Human Neurons
Authors: Guanqun Huang, Shuting Chen, Xiaoxia Chen, Jiajun Zheng, Zhuoran Xu, Abolfazl Doostparast Torshizi et al.
Frontiers in Neuroanatomy
-
Generation of the human induced pluripotent stem cell (hiPSC) line PSMi007-A from a Long QT Syndrome type 1 patient carrier of two common variants in the NOS1AP gene
Authors: M Mura, F Pisano, M Stefanello, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, PA Brink, M Gnecchi
Stem Cell Res, 2019-03-06;36(0):101416.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids
Authors: H Kim, HJ Park, H Choi, Y Chang, H Park, J Shin, J Kim, CJ Lengner, YK Lee, J Kim
Stem Cell Reports, 2019-02-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (TRNDi005-A) from a Mucopolysaccharidosis Type IVA (MPS IVA) patient carrying compound heterozygous p.R61W and p.WT405del mutations in the GALNS gene
Authors: R Li, A Baskfield, J Beers, J Zou, C Liu, CJ Alméciga-D, W Zheng
Stem Cell Res, 2019-02-15;36(0):101408.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy
Authors: T Klein, K Klug, L Henkel, CK Kwok, F Edenhofer, E Klopocki, I Kurth, N Üçeyler
Stem Cell Res, 2019-02-02;35(0):101396.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation
Authors: Joana D. Amaral, Dário Silva, Cecília M. P. Rodrigues, Susana Solá, Maria M. M. Santos
Frontiers in Chemistry
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The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer
Authors: S Melissarid, E Wiechec, M Magan, MV Jain, MK Chung, L Farnebo, K Roberg
Cancer Cell Int., 2019-01-14;19(0):16.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Single-cell transcriptomic analysis of mouse neocortical development
Authors: L Loo, JM Simon, L Xing, ES McCoy, JK Niehaus, J Guo, ES Anton, MJ Zylka
Nat Commun, 2019-01-11;10(1):134.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene
Authors: R Li, A Baskfield, Y Lin, J Beers, J Zou, C Liu, F Jaffré, AE Roberts, EA Ottinger, MI Kontaridis, W Zheng
Stem Cell Res, 2018-12-26;34(0):101374.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene
Authors: R Li, M Pradhan, M Xu, A Baskfield, A Farkhondeh, YS Cheng, J Beers, J Zou, C Liu, M Might, S Rodems, W Zheng
Stem Cell Res, 2018-12-05;34(0):101362.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SOX2 as a novel contributor of oxidative metabolism in melanoma cells
Authors: Elena Andreucci, Silvia Pietrobono, Silvia Peppicelli, Jessica Ruzzolini, Francesca Bianchini, Alessio Biagioni et al.
Cell Communication and Signaling
-
Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation
Authors: CP Cui, Y Zhang, C Wang, F Yuan, H Li, Y Yao, Y Chen, C Li, W Wei, CH Liu, F He, Y Liu, L Zhang
Nat Commun, 2018-11-07;9(1):4648.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient
Authors: S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, D Bachiller
Stem Cell Res, 2018-11-01;33(0):180-184.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
Authors: M Jeong, M O'Reilly, NK Kirkwood, J Al-Aama, M Lako, CJ Kros, L Armstrong
Cell Death Dis, 2018-09-11;9(9):922.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata)
Authors: R Nakai, M Ohnuki, K Kuroki, H Ito, H Hirai, R Kitajima, T Fujimoto, M Nakagawa, W Enard, M Imamura
Sci Rep, 2018-08-15;8(1):12187.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: ICC -
The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo
Authors: SU Vay, LJ Flitsch, M Rabenstein, R Rogall, S Blaschke, J Kleinhaus, N Reinert, A Bach, GR Fink, M Schroeter, MA Rueger
J Neuroinflammation, 2018-08-13;15(1):226.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708?G?>?C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene
Authors: T Klein, K Günther, CK Kwok, F Edenhofer, N Üçeyler
Stem Cell Res, 2018-08-10;31(0):222-226.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel
Authors: X Gao, JJ Yourick, RL Sprando
Stem Cell Res, 2018-07-27;31(0):193-196.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation
Authors: S Kwak, TW Kim, BH Kang, JH Kim, JS Lee, HT Lee, IY Hwang, J Shin, JH Lee, EJ Cho, HD Youn
Nucleic Acids Res., 2018-07-27;0(0):.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Lateral line placodes of aquatic vertebrates are evolutionarily conserved in mammals
Authors: Stefan Washausen, Wolfgang Knabe
Biology Open
-
Differential response in novel stem cell niches of the brain following cervical spinal cord injury and traumatic brain injury
Authors: A Falnikar, J Stratton, R Lin, CE Andrews, A Tyburski, VA Trovillion, C Gottschalk, B Ghosh, L Iacovitti, MB Elliott, AC Lepore
J. Neurotrauma, 2018-06-07;0(0):.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC-Fr -
Generation of dopamine neuronal-like cells from induced neural precursors derived from adult human cells by non-viral expression of lineage factors
Journal of Stem Cells and Regenerative Medicine
-
The non-canonical Wnt-PCP pathway shapes the caudal neural plate
Authors: B López-Esco, JM Caro-Vega, DS Vijayragha, TF Plageman, JA Sanchez-Al, RC Moreno, D Savery, J Márquez-Ri, LA Davidson, P Ybot-Gonzá
Development, 2018-05-08;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Oct4 suppresses IR‑induced premature senescence in breast cancer cells through STAT3- and NF‑ kappa B-mediated IL‑24 production
Authors: Jeong-Yub Kim, Jeong-Chul Kim, Ji-Yun Lee, Myung-Jin Park
International Journal of Oncology
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INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice
Authors: O Le, L Palacio, G Bernier, I Batinic-Ha, G Hickson, C Beauséjour
Stem Cell Reports, 2018-04-26;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
TFAP2C regulates transcription in human naive pluripotency by opening enhancers
Authors: WA Pastor, W Liu, D Chen, J Ho, R Kim, TJ Hunt, A Lukianchik, X Liu, JM Polo, SE Jacobsen, AT Clark
Nat. Cell Biol., 2018-04-25;20(5):553-564.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease
Authors: JY Lee, SH Han, MH Park, B Baek, IS Song, MK Choi, Y Takuwa, H Ryu, SH Kim, X He, EH Schuchman, JS Bae, HK Jin
Nat Commun, 2018-04-16;9(1):1479.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Generation of the human induced pluripotent stem cell (hiPSC) line PSMi002-A from a patient affected by the Jervell and Lange-Nielsen syndrome and carrier of two compound heterozygous mutations on the KCNQ1 gene
Authors: M Mura, YK Lee, M Ginevrino, R Zappatore, F Pisano, M Boni, F Dagradi, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
Stem Cell Res, 2018-04-07;29(0):157-161.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of the human induced pluripotent stem cell (hiPSC) line PSMi003-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1
Authors: M Mura, M Ginevrino, R Zappatore, F Pisano, M Boni, S Castellett, L Crotti, EM Valente, PJ Schwartz, M Gnecchi
Stem Cell Res, 2018-04-06;29(0):170-173.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation
Authors: NS Corsini, AM Peer, P Moeseneder, M Roiuk, TR Burkard, HC Theussl, I Moll, JA Knoblich
Cell Stem Cell, 2018-04-05;22(4):543-558.e12.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity
Authors: D Poppe, J Doerr, M Schneider, R Wilkens, JA Steinbeck, J Ladewig, A Tam, DE Paschon, PD Gregory, A Reik, CE Müller, P Koch, O Brüstle
Stem Cells Transl Med, 2018-03-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas
Authors: C Aaberg-Jes, MD Sørensen, ALSA Matos, JM Moreira, N Brünner, A Knudsen, BW Kristensen
BMC Cancer, 2018-03-09;18(1):270.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein
Authors: G V?fély, T Berecz, E Szabó, K Szebényi, E Hathy, TI Orbán, B Sarkadi, L Homolya, MC Marchetto, JM Réthelyi, Á Apáti
Mol. Cell. Neurosci., 2018-02-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs
Authors: M Chen, SH Laursen, M Habekost, CH Knudsen, SH Buchholdt, J Huang, F Xu, X Liu, L Bolund, Y Luo, P Nissen, F Febbraro, M Denham
Front Cell Dev Biol, 2018-02-06;6(0):5.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
Mol. Syst. Biol., 2018-01-29;14(1):e7952.
Species: Mouse
Sample Types: Whole Cells, Whole Tissue
Applications: ICC, IHC -
Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
Authors: M Naumann, A Pal, A Goswami, X Lojewski, J Japtok, A Vehlow, M Naujock, R Günther, M Jin, N Stanslowsk, P Reinhardt, J Sternecker, M Frickenhau, F Pan-Montoj, E Storkebaum, I Poser, A Freischmid, JH Weishaupt, K Holzmann, D Troost, AC Ludolph, TM Boeckers, S Liebau, S Petri, N Cordes, AA Hyman, F Wegner, SW Grill, J Weis, A Storch, A Hermann
Nat Commun, 2018-01-23;9(1):335.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury
Authors: A Alastrue-A, FJ Rodriguez-, EL Mocholi, F De Giorgio, S Erceg, V Moreno-Man
Int J Mol Sci, 2018-01-09;19(1):.
Species: Rat
Sample Types: Cell Lysates
Applications: Western Blot -
ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development
Authors: Alex M. Rohacek, Thomas W. Bebee, Richard K. Tilton, Caleb M. Radens, Chris McDermott-Roe, Natoya Peart et al.
Developmental Cell
-
Comparison among conventional and advanced MRI, 18F-FDG PET/CT, phenotype and genotype in glioblastoma
Authors: Maria Consuelo Valentini, Marta Mellai, Laura Annovazzi, Antonio Melcarne, Tetyana Denysenko, Paola Cassoni et al.
Oncotarget
-
Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug
Authors: M Okada, H Takeda, H Sakaki, K Kuramoto, S Suzuki, T Sanomachi, K Togashi, S Seino, C Kitanaka
Oncotarget, 2017-10-24;8(55):94872-94882.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1
Authors: K Hirano, M Namihira
FEBS Open Bio, 2017-10-17;7(12):1932-1942.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Extensive characterization of feline intra-abdominal adipose-derived mesenchymal stem cells
Authors: Hee-Ryang Kim, Jienny Lee, Jeong Su Byeon, Na-Yeon Gu, Jiyun Lee, In-Soo Cho et al.
Journal of Veterinary Science
-
Laminin ?5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro
Authors: A Hyysalo, M Ristola, ME Mäkinen, S Häyrynen, M Nykter, S Narkilahti
Stem Cell Res, 2017-09-12;24(0):118-127.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
Authors: Yalin Zhang, Min Soo Kim, Baosen Jia, Jingqi Yan, Juan Pablo Zuniga-Hertz, Cheng Han et al.
Nature
-
Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists☆
Authors: Sergey A. Shiryaev, Chen Farhy, Antonella Pinto, Chun-Teng Huang, Nicole Simonetti, Annie Elong Elong Ngono et al.
Antiviral Research
-
SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer
Authors: Lúcia L. Correia, Jo-Anne Johnson, Peter McErlean, Julien Bauer, Hassan Farah, Doris M. Rassl et al.
American Journal of Respiratory and Critical Care Medicine
-
Generation of an ASGR1 homozygous mutant human embryonic stem cell line WAe001-A-6 using CRISPR/Cas9
Authors: Y Xu, Y Wu, D Guo, G Gao, K Lai, F Yang, K Wang, H Wu, L Lai, J Li, K Xu, YX Li
Stem Cell Res, 2017-05-19;22(0):29-32.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Nicotinamide metabolism regulates glioblastoma stem cell maintenance
Authors: J Jung, LJY Kim, X Wang, Q Wu, T Sanvoranar, CG Hubert, BC Prager, LC Wallace, X Jin, SC Mack, JN Rich
JCI Insight, 2017-05-18;2(10):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia
Authors: P Wang, C Lan, S Xiong, X Zhao, Y Shan, R Hu, W Wan, S Yu, B Liao, G Li, J Wang, D Zou, B Chen, H Feng, N Wu
Oncotarget, 2017-04-25;8(17):28074-28092.
Species: Human
Sample Types: Cell Lysates, Whole Cells
Applications: ICC, Western Blot -
Spatial development of gingival fibroblasts and dental pulp cells: Effect of extracellular matrix
Authors: G Kaufman, D Skrtic
Tissue Cell, 2017-04-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
Authors: X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJ Kim, BC Prager, WA Flavahan, X Liu, M Singer, CG Hubert, TE Miller, W Zhou, Z Huang, X Fang, A Regev, ML Suvà, TH Hwang, JW Locasale, S Bao, JN Rich
Nat. Neurosci, 2017-03-27;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa
Authors: TP Sharma, LA Wiley, SS Whitmore, KR Anfinson, CM Cranston, DJ Oppedal, HT Daggett, RF Mullins, BA Tucker, EM Stone
Stem Cell Res, 2017-03-18;21(0):58-70.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice
Authors: Enheng Dong, Amelia Bachleda, Yubin Xiong, Shoji Osawa, Ellen R. Weiss
Mol. Vis
-
Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo
Authors: SS Jensen, SA Petterson, B Halle, C Aaberg-Jes, BW Kristensen
BMC Cancer, 2017-03-07;17(1):178.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
Authors: G Riddick, S Kotliarova, V Rodriguez, HS Kim, A Linkous, AJ Storaska, S Ahn, J Walling, G Belova, HA Fine
Sci Rep, 2017-03-03;7(0):43605.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment
Authors: Andrew J. Price, Eva Y. Huang, Vittorio Sebastiano, Alexander R. Dunn
Biomaterials
-
A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases
Authors: I Karakikes, V Termglinch, DA Cepeda, J Lee, S Diecke, A Hendel, I Itzhaki, M Ameen, R Shrestha, H Wu, N Ma, NY Shao, T Seeger, NA Woo, KD Wilson, E Matsa, MH Porteus, V Sebastiano, JC Wu
Circ. Res, 2017-02-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma
Authors: R Bayat Mokh, N Baluch, M Ka Hon Tsu, S Kumar, T S Homayoun, K Aitken, B Das, S Baruchel, H Yeger
BMC Cancer, 2017-02-24;17(1):156.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding
Authors: S Falk, S Bugeon, J Ninkovic, GA Pilz, MP Postiglion, H Cremer, JA Knoblich, M Götz
Neuron, 2017-02-22;93(4):777-791.e3.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells
Authors: Raul Bardini Bressan, Pooran Singh Dewari, Maria Kalantzaki, Ester Gangoso, Mantas Matjusaitis, Claudia Garcia-Diaz et al.
Development
-
Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells
Authors: T Yamashita, Y Miyamoto, Y Bando, T Ono, S Kobayashi, A Doi, T Araki, Y Kato, T Shirakawa, Y Suzuki, J Yamauchi, S Yoshida, N Sato
PLoS ONE, 2017-02-13;12(2):e0171947.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
Authors: AG Alvarado, PS Thiagaraja, EE Mulkearns-, DJ Silver, JS Hale, TJ Alban, SM Turaga, A Jarrar, O Reizes, MS Longworth, MA Vogelbaum, JD Lathia
Cell Stem Cell, 2017-01-12;20(4):450-461.e4.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells
Authors: HO King, T Brend, HL Payne, A Wright, TA Ward, K Patel, T Egnuni, LF Stead, A Patel, H Wurdak, SC Short
Stem Cell Reports, 2017-01-10;8(1):125-139.
Species: Human
Sample Types: Whole Cells, Whole Tissue
Applications: ICC, IHC -
The evolutionally-conserved function of group B1 Sox family members confers the unique role of Sox2 in mouse ES cells
Authors: Hitoshi Niwa, Akira Nakamura, Makoto Urata, Maki Shirae-Kurabayashi, Shigehiro Kuraku, Steven Russell et al.
BMC Evolutionary Biology
-
SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis
PLoS Biol., 2016-11-23;14(11):e1002581.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Derivation of Corneal Keratocyte-Like Cells from Human Induced Pluripotent Stem Cells
Authors: Richard W. Naylor, Charles N. J. McGhee, Chad A. Cowan, Alan J. Davidson, Teresa M. Holm, Trevor Sherwin
PLOS ONE
-
Efficient long-term cryopreservation of pluripotent stem cells at −80 °C
Authors: Ye Yuan, Ying Yang, Yuchen Tian, Jinkyu Park, Aihua Dai, R. Michael Roberts et al.
Scientific Reports
-
ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA
Oncogene, 2016-09-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9
Stem Cell Res, 2016-09-16;17(2):430-432.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9
Stem Cell Res, 2016-09-15;17(2):441-443.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
A new gain-of-function mouse line to study the role of Wnt3a in development and disease
Authors: Ravindra B. Chalamalasetty, Rieko Ajima, Robert J. Garriock, Mark W. Kennedy, Lino Tessarollo, Terry P. Yamaguchi
genesis
-
Enhancing the Three-Dimensional Structure of Adherent Gingival Fibroblasts and Spheroids via a Fibrous Protein-Based Hydrogel Cover
Cells Tissues Organs (Print), 2016-08-30;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A
Stem Cells Transl Med, 2016-08-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr -
cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness
Sci Rep, 2016-07-29;6(0):30742.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells
Authors: Annabelle Congras
Sci Rep, 2016-06-01;6(0):27059.
Species: Porcine
Sample Types: Whole Cells
Applications: IHC -
Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds
Authors: Kristan S. Worthington, Luke A. Wiley, C. Allan Guymon, Aliasger K. Salem, Budd A. Tucker
Journal of Ocular Pharmacology and Therapeutics
-
Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion
Stem Cells, 2016-05-27;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype
PLoS ONE, 2016-05-12;11(5):e0155106.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo
Authors: Masashi Okada, Kenta Kuramoto, Hiroyuki Takeda, Hikaru Watarai, Hirotsugu Sakaki, Shizuka Seino et al.
Oncotarget
-
Angiogenic activity mediates bone repair from human pluripotent stem cell-derived osteogenic cells
Authors: Li Zou, Qingshan Chen, Zachary Quanbeck, Joan E. Bechtold, Dan S. Kaufman
Scientific Reports
-
Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage
Authors: Steven A. Jackson, Zachariah P.G. Olufs, Khoa A. Tran, Nur Zafirah Zaidan, Rupa Sridharan
Stem Cell Reports
-
North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13
Authors: Kent W. Small, Adam P. DeLuca, S. Scott Whitmore, Thomas Rosenberg, Rosemary Silva-Garcia, Nitin Udar et al.
Ophthalmology
-
Age Does Matter: A Pilot Comparison of Placenta-Derived Stromal Cells for in utero Repair of Myelomeningocele Using a Lamb Model
Authors: Erin G. Brown, Benjamin A. Keller, Lee Lankford, Christopher D. Pivetti, Shinjiro Hirose, Diana L. Farmer et al.
Fetal Diagnosis and Therapy
-
Human Induced Pluripotent Stem Cell NEUROG2 Dual Knockin Reporter Lines Generated by the CRISPR/Cas9 System
Authors: Shenglan Li, Haipeng Xue, Jianbo Wu, Mahendra S. Rao, Dong H. Kim, Wenbin Deng et al.
Stem Cells and Development
-
Osteopontin mediates survival, proliferation and migration of neural stem cells through the chemokine receptor CXCR4
Authors: Monika Rabenstein, Joerg Hucklenbroich, Antje Willuweit, Anne Ladwig, Gereon Rudolf Fink, Michael Schroeter et al.
Stem Cell Research & Therapy
-
Rapid generation of secondary fibroblasts through teratoma formation
Authors: Sang Mi Cho, Jung Sun Park, Byungkuk Min, Sujin Kwon, Yong-Kook Kang
BioTechniques
-
Mef2c-F10N enhancer driven beta -galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells
Authors: Kazushi Aoto, Lisa L. Sandell, Naomi E. Butler Tjaden, Kobe C. Yuen, Kristin E. Noack Noack Watt, Brian L. Black et al.
Developmental Biology
-
Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation.
Authors: Garriock R, Chalamalasetty R, Kennedy M, Canizales L, Lewandoski M, Yamaguchi T
Development, 2015-05-01;142(9):1628-38.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
Authors: Kim, Dohoon, Fiske, Brian P, Birsoy, Kivanc, Freinkman, Elizavet, Kami, Kenjiro, Possemato, Richard, Chudnovsky, Yakov, Pacold, Michael, Chen, Walter W, Cantor, Jason R, Shelton, Laura M, Gui, Dan Y, Kwon, Manjae, Ramkissoon, Shakti H, Ligon, Keith L, Kang, Seong Wo, Snuderl, Matija, Vander Heiden, Matthew, Sabatini, David M
Nature, 2015-04-08;520(7547):363-7.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Autologous anti-SOX2 antibody responses reflect intensity but not frequency of antigen expression in small cell lung cancer
Authors: Sukru Atakan, Hulya Bayiz, Serpil Sak, Alper Poyraz, Burcak Vural, Azmi Serhat Yildirim et al.
BMC Clinical Pathology
-
Isolation of cancer stem cells from three human glioblastoma cell lines: characterization of two selected clones.
Authors: Iacopino F, Angelucci C, Piacentini R, Biamonte F, Mangiola A, Maira G, Grassi C, Sica G
PLoS ONE, 2014-08-14;9(8):e105166.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
CD133-positive cancer stem cells from colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile
Authors: Zangiacomi Vincent, Kenichi Urakami, Koji Maruyama, Ken Yamaguchi, Masatoshi Kusuhara
Genes & Cancer
-
Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency.
Authors: Onishi K, Tonge P, Nagy A, Zandstra P
Stem Cell Reports, 2014-06-06;3(1):156-68.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.
Authors: Yan K, Wu Q, Yan D, Lee C, Rahim N, Tritschler I, DeVecchio J, Kalady M, Hjelmeland A, Rich J
Genes Dev, 2014-05-01;28(10):1085-100.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Fluoxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro.
Authors: Sousa-Ferreira L, Aveleira C, Botelho M, Alvaro A, Pereira de Almeida L, Cavadas C
PLoS ONE, 2014-03-05;9(3):e88917.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
A single-cell and feeder-free culture system for monkey embryonic stem cells.
Authors: Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, Kato H, Torii R, Sato N
PLoS ONE, 2014-02-05;9(2):e88346.
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: ICC -
EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.
Authors: Miao, H, Gale, N W, Guo, H, Qian, J, Petty, A, Kaspar, J, Murphy, A J, Valenzuela, D M, Yancopoulos, G, Hambardzumyan, D, Lathia, J D, Rich, J N, Lee, J, Wang, B
Oncogene, 2014-02-03;34(5):558-67.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
Authors: Sherwood, Richard, Hashimoto, Tatsunor, O'Donnell, Charles, Lewis, Sophia, Barkal, Amira A, van Hoff, John Pet, Karun, Vivek, Jaakkola, Tommi, Gifford, David K
Nat Biotechnol, 2014-01-19;32(2):171-8.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Chondroitin sulfate is indispensable for pluripotency and differentiation of mouse embryonic stem cells.
Authors: Izumikawa, Tomomi, Sato, Ban, Kitagawa, Hiroshi
Sci Rep, 2014-01-15;4(0):3701.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC, Western Blot -
Zrf1 is required to establish and maintain neural progenitor identity.
Authors: Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah S, Graf T, Broccoli V, Di Croce L
Genes Dev, 2014-01-15;28(2):182-97.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex.
Authors: Minamide, Ryohei, Fujiwara, Kazushir, Hasegawa, Koichi, Yoshikawa, Kazuaki
PLoS ONE, 2014-01-02;9(1):e84460.
Species: Mouse
Sample Types: Tissue Homogenates, Whole Cells, Whole Tissue
Applications: ICC, IHC-P, Western Blot -
The subventricular zone is able to respond to a demyelinating lesion after localized radiation.
Authors: Capilla-Gonzalez V, Guerrero-Cazares H, Bonsu J, Gonzalez-Perez O, Achanta P, Wong J, Garcia-Verdugo J, Quinones-Hinojosa A
Stem Cells, 2014-01-01;32(1):59-69.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.
Authors: Volonte A, Di Tomaso T, Spinelli M, Todaro M, Sanvito F, Albarello L, Bissolati M, Ghirardelli L, Orsenigo E, Ferrone S, Doglioni C, Stassi G, Dellabona P, Staudacher C, Parmiani G, Maccalli C
J Immunol, 2013-11-25;192(1):523-32.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Oct4 is required ~E7.5 for proliferation in the primitive streak.
Authors: DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra P, Nagy A, van der Kooy D
PLoS Genet, 2013-11-14;9(11):e1003957.
Species: Mouse
Sample Types: Embryo
Applications: IHC-P -
Evidence for NG2-glia Derived, Adult-Born Functional Neurons in the Hypothalamus
Authors: Sarah C. Robins, Eric Trudel, Olivia Rotondi, Xiaohong Liu, Tina Djogo, Darya Kryzskaya et al.
PLoS ONE
-
Assessment of Adult Neurogenesis in Mice
Authors: Yung‐Wei Pan, Wenbin Wang, Zhengui Xia
Current Protocols in Toxicology
-
Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb.
Authors: Li, Tan, Pan, Yung-Wei, Wang, Wenbin, Abel, Glen, Zou, Junhui, Xu, Lihong, Storm, Daniel R, Xia, Zhengui
PLoS ONE, 2013-04-22;8(4):e61948.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.
Authors: Najm, Fadi J, Lager, Angela M, Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V, Factor, Daniel C, Karl, Robert T, Maeda, Tadao, Miller, Robert H, Tesar, Paul J
Nat Biotechnol, 2013-04-14;31(5):426-33.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus.
Authors: Haan, Niels, Goodman, Timothy, Najdi-Samiei, Alaleh, Stratford, Christin, Rice, Ritva, El Agha, Elie, Bellusci, Saverio, Hajihosseini, Mohammad
J Neurosci, 2013-04-03;33(14):6170-80.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Embryonic stem cell-based modeling of tau pathology in human neurons.
Authors: Mertens J, Stuber K, Poppe D, Doerr J, Ladewig J, Brustle O, Koch P
Am J Pathol, 2013-03-13;182(5):1769-79.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Fast, Potent Pharmacological Expansion of Endogenous Hes3+/Sox2+ Cells in the Adult Mouse and Rat Hippocampus
Authors: Simone Pacioni, Maria Adele Rueger, Giuseppe Nisticò, Stefan R. Bornstein, Deric M. Park, Ron D. McKay et al.
PLoS ONE
-
IKK beta /NF-kappa B disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes
Authors: Juxue Li, Yizhe Tang, Dongsheng Cai
Nature Cell Biology
-
Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium.
Authors: Hayashi, Ryuhei, Ishikawa, Yuki, Ito, Miyuki, Kageyama, Tomofumi, Takashiba, Kuniko, Fujioka, Tsuyoshi, Tsujikawa, Motokazu, Miyoshi, Hiroyuki, Yamato, Masayuki, Nakamura, Yukio, Nishida, Kohji
PLoS ONE, 2012-09-24;7(9):e45435.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Sex-determining region Y-box 2 (SOX2) expression predicts poor prognosis in human ovarian carcinoma
Authors: Jing Zhang, Doo Young Chang, Imelda Mercado-Uribe, Jinsong Liu
Human Pathology
-
Recombinant Rabbit Leukemia Inhibitory Factor and Rabbit Embryonic Fibroblasts Support the Derivation and Maintenance of Rabbit Embryonic Stem Cells
Authors: Fei Xue, Yinghong Ma, Y. Eugene Chen, Jifeng Zhang, Tzu-An Lin, Chien-Hong Chen et al.
Cellular Reprogramming
-
Analysis of SOX2 expression in developing human testis and germ cell neoplasia
Authors: Si B. Sonne, Rebecca M. Perrett, John E. Nielsen, Melissa A. Baxter, David M. Kristensen, Henrik Leffers et al.
The International Journal of Developmental Biology
-
AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells
Authors: Dawei Zhang, Tianyun Zhao, Haw Siang Ang, Peini Chong, Ryotaro Saiki, Kazuei Igarashi et al.
Genes & Development
-
REST regulates oncogenic properties of glioblastoma stem cells.
Authors: Kamal MM, Sathyan P, Singh SK, Zinn PO, Marisetty AL, Liang S, Gumin J, El-Mesallamy HO, Suki D, Colman H, Fuller GN, Lang FF, Majumder S
Stem Cells, 2012-03-01;30(3):405-14.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members
Authors: David T. Madden, Diana Davila-Kruger, Simon Melov, Dale E. Bredesen
PLoS ONE
-
Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.
Authors: Mahar I, Tan S, Davoli MA, Dominguez-Lopez S, Qiang C, Rachalski A, Turecki G, Mechawar N
PLoS ONE, 2011-10-19;6(10):e26610.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells.
Authors: Lathia JD, Gallagher J, Myers JT
PLoS ONE, 2011-09-22;6(9):e24807.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres
Authors: Valentina Caldera, Marta Mellai, Laura Annovazzi, Angela Piazzi, Michele Lanotte, Paola Cassoni et al.
Journal of Oncology
-
Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel.
Authors: Hibino N, Villalona G, Pietris N
FASEB J., 2011-05-12;25(8):2731-9.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Human haploid cells differentiated from meiotic competent clonal germ cell lines that originated from embryonic stem cells.
Authors: West FD, Mumaw JL, Gallegos-Cardenas A, Young A, Stice SL
Stem Cells Dev., 2010-12-02;20(6):1079-88.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells.
Authors: Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, Nacey C, McGee J, Lindsey M, Fury B, Bauer G, Nolta JA, Anderson JS
Mol. Ther., 2010-11-30;19(3):584-93.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination
Authors: Helena Johansson, Stina Simonsson
ImpactJ
-
Directed Differentiation of Neural-stem cells and Subtype-Specific Neurons from hESCs
Authors: Bao-Yang Hu, Su-Chun Zhang
Cellular Programming and Reprogramming
-
Paternal recognition of adult offspring mediated by newly generated CNS neurons.
Authors: Mak GK, Weiss S
Nat. Neurosci., 2010-05-09;13(6):753-8.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography.
Authors: Rueger MA, Backes H, Walberer M, Neumaier B, Ullrich R, Simard ML, Emig B, Fink GR, Hoehn M, Graf R, Schroeter M
J. Neurosci., 2010-05-05;30(18):6454-60.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1, and TCL1 in primary mediastinal germ cell tumors.
Authors: Liu A, Cheng L, Du J, Peng Y, Allan RW, Wei L, Li J, Cao D
Am. J. Surg. Pathol., 2010-05-01;34(5):697-706.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Epigenetic changes to human umbilical cord blood cells cultured with three proteins indicate partial reprogramming to a pluripotent state.
Authors: Wong CJ, Casper RF, Rogers IM
Exp. Cell Res., 2010-01-22;316(6):927-39.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The intracellular distribution of the ES cell totipotent markers OCT4 and Sox2 in adult stem cells differs dramatically according to commercial antibody used.
J. Cell. Biochem., 2009-04-01;106(5):867-77.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Efficient Serum-Free Derivation of Oligodendrocyte Precursors from Neural Stem Cell-Enriched Cultures.
Authors: Rao RC, Boyd J, Padmanabhan R, Chenoweth JG, McKay RD
Stem Cells, 2009-01-01;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
Authors: Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, Ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP
J. Neurosci., 2008-12-17;28(51):13978-84.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells.
Authors: Neganova I, Zhang X, Atkinson S, Lako M
Oncogene, 2008-09-22;28(1):20-30.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
Authors: Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL
Nat. Cell Biol., 2008-06-22;10(7):837-48.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria.
Authors: Gunther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K
Oncogene, 2007-11-26;27(20):2897-909.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry, ICC -
Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1.
Authors: Hattori Y, Ohta S, Hamada K, Yamada-Okabe H, Kanemura Y, Matsuzaki Y, Okano H, Kawakami Y, Toda M
Biochem. Biophys. Res. Commun., 2007-10-15;364(4):737-42.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy.
Authors: Schmitz M, Temme A, Senner V, Ebner R, Schwind S, Stevanovic S, Wehner R, Schackert G, Schackert HK, Fussel M, Bachmann M, Rieber EP, Weigle B
Br. J. Cancer, 2007-03-20;96(8):1293-301.
Species: Human
Sample Types: Cell Lysates, Whole Cells, Whole Tissue
Applications: ICC, IHC-P, Western Blot -
Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage.
Authors: Pankratz MT, Li XJ, Lavaute TM, Lyons EA, Chen X, Zhang SC
Stem Cells, 2007-03-01;25(6):1511-20.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue.
Authors: Shin S, Sun Y, Liu Y, Khaner H, Svant S, Cai J, Xu QX, Davidson BP, Stice SL, Smith AK, Goldman SA, Reubinoff BE, Zhan M, Rao MS, Chesnut JD
Stem Cells, 2007-02-01;25(5):1298-306.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats.
Authors: Kobayashi T, Ahlenius H, Thored P, Kobayashi R, Kokaia Z, Lindvall O
Stroke, 2006-07-27;37(9):2361-7.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Brain is an endocrine organ through secretion and nuclear transfer of parathymosin.
Authors: Yu, B, Tang, Y Et al.
Life Sci Alliance
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The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia
Authors: Yan J, Goerne T, Zelmer A, et al.
Front Cell Dev Biol
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An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
Authors: P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, M Nordenskjö, P Micke, D Maltseva, AG Tonevitsky, V Millischer, J Carlos Vil, S Kadekar, M Gaetani, K Altynbekov, A Kel, PO Berggren, O Simonson, KH Grinnemo, R Holmdahl, S Rodin, RA Zubarev
Nature Communications, 2021-11-12;12(1):6558.
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Regulation of prefrontal patterning and connectivity by retinoic acid
Authors: M Shibata, K Pattabiram, B Lorente-Ga, D Andrijevic, SK Kim, N Kaur, SK Muchnik, X Xing, G Santpere, AMM Sousa, N Sestan
Nature, 2021-10-01;0(0):.
FAQs
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What is the light chain of Human/Mouse/Rat SOX2 Antibody, Catalog #s MAB2018, MAB2018R and IC2018?
Catalog #s MAB2018, MAB2018R and IC2018 all have a kappa light chain.
Reviews for Human/Mouse/Rat SOX2 Antibody
Average Rating: 4.6 (Based on 11 Reviews)
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SOX2 expression was examined by WB on two colorectal cancer cell lines. A clear band at 35KD was observed.
On the photo SOX2 is red, nuclear DAPI is blue.
Cells: human induced pluripotent stem cells
Primary antibody: anti-human SOX2 (1:200), O/N incubation at 4 degrees
Secondary antibody: anti-mouse AF488
Red: sox2. Green: ki67. Blue: DAPI. Postnatal day 7 sub-ventricular zone. 2% PFA fixed. Heat-mediated antigen retrieval. Blocked with 10% donkey serum, 0.5% Triton in PBS for 1h. Dilution 1:100.
I used this antibody to test Sox2 expression in iPS cells derived from fibroblasts of Sanfilippo syndrome C patients.
Specificity: Specific
Sensitivity: Sensitive
Buffer: 5% BSA in TBST
Dilution: 1/1000
Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: 1% BSA + 0.3% Triton X-100 in PBS
Dilution: 1/100