E-Selectin/CD62E: Products
E-Selectin, also known as CD62E, is expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. It is a lectin that binds to sialylated or fucosylated molecules on neutrophils, monocytes, and a subset of memory T cells. E-Selectin mediates the initial attachment of circulating leukocytes to the blood vessel wall during inflammation. This interaction permits leukocytes to roll along the vascular endothelium. Subsequent ICAM-1 and VCAM-1 mediated adhesion leads to extravasation of the leukocyte through the blood vessel wall into the extracellular matrix tissue.
Products:
- Primary Antibodies
- Proteins & Enzymes
- ELISAs
- cDNA Clones
- Proteome Profiler Antibody Arrays
- Simple Plex Assays
- Luminex Assays
- Small Molecules
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