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IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.
To assist researchers with their IL-6-dependent studies and further our understanding of IL-6 functions, R&D Systems, a Bio-Techne brand, offers a comprehensive range of IL-6 Antibody products, IL-6 Proteins and Enzymes, IL-6 ELISAs, IL-6 Luminex Assays and more. Use the filter on the left to drill down to the IL-6 product that best fits your needs.
Simple Plex 32x6 panel containing IL-10, IL-2, IFN-gamma 3rd Gen, TNF-alpha 2nd Gen, IL-8/CXCL8, and IL-6 2nd Gen with sample diluent SD13, and wash buffer. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex 32x4 mouse panel containing IL-2, IL-6, IFN-gamma, and TNF-alpha with sample diluent SD09. Part # starting with ST01 ships in 2-3 days. Sample type indicated with MP (Plasma/Serum).
Simple Plex 16x4 panel containing IL-1 beta / IL-1F2, IL-6 3rd Gen, IL-8/CXCL8, and TNF-alpha 2nd Gen with sample diluent SD13. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex Human IL-6 3rd Gen assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex 32x6 panel containing IL-10 2nd Gen, IL-2, IFN-gamma 3rd Gen, TNF-alpha 2nd Gen, IL-8/CXCL8, and IL-6 3rd Gen with sample diluent SD13, and wash buffer. Part # starting with ST01 ships in 3-5 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex 32x4 panel containing IL-1b,IL-6 3rd gen,IL-8,TNF-a 2nd gen with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).
Simple Plex 32x4 panel containing IL-6 3rd gen, Procalcitonin, TREM-1, uPAR with sample diluent SD13. Part # starting with ST01 ships in 2-3 days. Sample type indicated with PS (Plasma/Serum).
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
