TSLPR: Products
TSLPR, also known as Delta and CRLM-2, is expressed on regulatory T cells (Treg), some subsets of helper T cells, innate lymphoid cells (ILC), monocytes, and dendritic cells. It associates with IL-7R alpha to form a high-affinity receptor complex for epithelium-derived TSLP (thymic stromal lymphopoeitin). TSLP is a homeostatic cytokine that induces the release of T cell-attracting chemokines and enhances the maturation of CD1c+ dendritic cells.
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