332 results for "VEGFR3/Flt-4" in Products

VEGFR3/Flt-4 Products

VEGFR1 (Flt-1), VEGFR2 (KDR/Flk-1), and VEGFR3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGFR2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGFR3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Reactivity: Human
Applications:
Human Luminex Discovery Assay

Build your own Luminex Assay with our Luminex Assay Customization Tool

Reactivity: Mouse
Details: Goat IgG Polyclonal
Applications: WB, Flow, CyTOF-ready
Detection of VEGFR3/Flt-4 antibody in bEnd.3 Mouse Cell Line antibody by Flow Cytometry.
(17)
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Reactivity: Human
Details: Goat IgG Polyclonal
Applications: IHC, WB
VEGFR3/Flt-4 antibody in Human Cervical Squamous Metaplasia by Immunohistochemistry (IHC-P).
(5)
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Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Reactivity: Human
Applications:
Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)
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Reactivity: Human
Source: NS0
Accession #: P35916
Applications: Binding Activity
R&D Systems Recombinant Proteins and Enzymes
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Reactivity: Human
Assay Range: 93.8-6000 pg/mL
Applications: ELISA
Human VEGF R3 / Flt-4 ELISA Standard Curve
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VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Alternate Names: Semaxinib
Chemical Name: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Purity: ≥98%
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
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Reactivity: Mouse
Source: Sf 21 (baculovirus)
Accession #: P35917
Applications: Binding Activity
R&D Systems Recombinant Proteins and Enzymes
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Reactivity: Human
Applications: ELISA
(2)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #54733
Applications: Flow
Detection of VEGF R3/Flt-4 antibody in HUVEC Human Cells antibody by Flow Cytometry.
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #9D9
Applications: IHC, WB, ELISA, Flow, CyTOF-ready
Immunohistochemistry: VEGFR3/Flt-4 Antibody (9D9) - Azide and BSA Free [NBP1-18651]
(6)
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Reactivity: Human
Details: Rat IgG2A Monoclonal Clone #1091512
Applications: mIF, IHC
(4)
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Reactivity: Mouse
Details: Rat IgG2a Kappa Monoclonal Clone #AFL4
Applications: IHC, WB, Flow, Dual ISH-IHC, IP
Immunohistochemistry-Frozen: VEGFR3/Flt-4 Antibody (AFL4) - BSA Free [NBP1-43259]
(2)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #54733
Applications: Flow
Detection of VEGF R3/Flt-4 antibody in HUVEC Human Cells antibody by Flow Cytometry.
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Reactivity: Mouse
Details: Goat IgG Polyclonal
Applications: WB, ELISA(Det), Flow
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #54716
Applications: ELISA(Cap)
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Reactivity: Mouse
Details: Rat IgG1 Monoclonal Clone #102806
Applications: WB
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #54733
Applications: ELISA(Det), Flow
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Reactivity: Mouse
Details: Rat IgG2A Monoclonal Clone #102804
Applications: ELISA(Cap)
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Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT

Chemical Name: 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
Purity: ≥98%
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
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Reactivity: Mouse
Details: Rat IgG2 Monoclonal Clone #RM0003-5F63
Applications: IHC, WB, ICC/IF
Immunohistochemistry-Paraffin: VEGFR3/Flt-4 Antibody (RM0003-5F63) - Azide and BSA Free [NB110-61018]
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Potent VEGFR, PDGFRβ and KIT inhibitor

Alternate Names: SU 11248
Chemical Name: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt
Purity: ≥98%
Potent VEGFR, PDGFRβ and KIT inhibitor
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Potent VEGFR-1, -2 and -3 inhibitor

Chemical Name: N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide
Purity: ≥98%
Potent VEGFR-1, -2 and -3 inhibitor
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Potent inhibitor of VEGFR, PDGFR and FGFR

Chemical Name: 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline
Purity: ≥98%
Potent inhibitor of VEGFR, PDGFR and FGFR
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